LOCUS       KCWK01000001             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:18077:14104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000001
VERSION     KCWK01000001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18077:14104"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65739.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       407..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           91 a          160 c          124 g          105 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tcgtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacacagc cgccctcagt gtctggggcc ccagggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg aggttattat atatcctggt accagcagct cccaggaacg
      241 gcccccaaac tcctcgtcta tgacaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggttc ctcagccacc ctgaccatca ctgggctcca gactgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagtctga gtgctcgggt attcggcgga
      421 gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000002             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:8465:10667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000002
VERSION     KCWK01000002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8465:10667"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65740.1"
                     /translation="YYYCSSYAGSHTYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           78 a          165 c          121 g          111 t
ORIGIN      
        1 acatgggggc tggggtctca gggggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacagggtcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggttc cagcagcacc ccggcaaagc
      241 ccccaaactc atgatttatg atgtcactca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctggctaca cggcctccct gaccatctct gggctccagg ctgcggatga
      361 ggcttattat tactgcagct catatgcggg cagccacact tacatcttcg gtactgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000003             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:7372:14507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000003
VERSION     KCWK01000003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7372:14507"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65741.1"
                     /translation="DYYCQVWDSSSDHWVF"
     J_segment       393..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          148 c          136 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctc gctcactgca cagcctctgc ggtctcctat gaactgactc
      121 agccaccctc ggtgtcagtg tccccaggac agatggccag tatcacctgt gggggagacg
      181 accttggaag taaatatgtg cactggtacc agcagaggcc agcacagtcc cctgtactgg
      241 tcatctatga tgataccaaa cggccctcag ggatccctga gcgattctct ggctccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cgggattgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgggtttt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000004             336 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:6798:8173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000004
VERSION     KCWK01000004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 336)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:6798:8173"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..298
                     /note="immunoglobulin light chain variable region"
     V_region        7..298
     V_segment       7..261
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <223..>270
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65742.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       262..298
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        299..>336
                     /gene="IGLC"
BASE COUNT           67 a          107 c           86 g           76 t
ORIGIN      
        1 acatgggcca ggaagagtgt ctccatctcc tgttcgggaa gcagctccaa catcggaagt
       61 catagtgtct cctggtacca gcaactccca ggaacagctc ccaaactcct catctattat
      121 agtgatcaac gagcctcagg tgtctctgac cgattctctg gctcccagtc tggcacgtca
      181 gcctccctgg ccatcagtgg gctccagacc gaggatgagg ctgattatta ctgcgcggca
      241 tgggatgata gcctgagcgg ttacatcttc ggtgctggga cccggctcac cgtcctaggt
      301 cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000005             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:2445:11142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000005
VERSION     KCWK01000005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:2445:11142"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..429
                     /note="immunoglobulin light chain variable region"
     V_region        84..429
     V_segment       84..392
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65743.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       393..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          160 c          105 g          112 t
ORIGIN      
        1 acatggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc ctgctcctct
       61 ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc ctctcagcat
      121 ctccgggaac atcagccaga ctcagctgca ccttgagcag tggcaatgtt ggtagttaca
      181 gcattttctg gtaccagcag aagccaggga gtcctccccg gtaccttctt tactactact
      241 cagactcaag taaccaccag gactctggag tccccagccg cttctctggt tcgaaagatg
      301 cttcagccaa tgcagggctt ttactgatct ctgggctcca gtctgaagat gaggctgact
      361 attactgtgc cacatggcac agcagcgctt cttacatctt cggtcctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01000006             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:5677:10938
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000006
VERSION     KCWK01000006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5677:10938"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65744.1"
                     /translation="DYYCQSADTSGNHPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          108 a          136 c          120 g           99 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgaac tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatgctcagt ggttccagca gaagccaggc caggccccta tactggtaat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacagtt tccttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagca gacaccagtg gtaatcatcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000007             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:16163:19038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000007
VERSION     KCWK01000007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16163:19038"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65745.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          146 c          131 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg tcccctcggt cactctcttc ccg
//
LOCUS       KCWK01000008             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:27671:11331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000008
VERSION     KCWK01000008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:27671:11331"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65746.1"
                     /translation="HYYCQVWDINTDHVLF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          141 c          132 g          102 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga tgttgtgaat tggtaccacc agaagccacc gcaggcccct gtactggtca
      241 tctatgctaa tagcgatcgg ccctcaggga tccctgagcg attctctggc tccatatcag
      301 ggaacacggc caccctgacc atcaacgggg tcgaggccgg ggatgaggct cactattact
      361 gtcaggtgtg ggacattaat actgatcatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000009             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:24220:20670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000009
VERSION     KCWK01000009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:24220:20670"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65747.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>476
                     /gene="IGLC"
BASE COUNT           93 a          157 c          118 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca aacctttgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca tatacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatacaaatc agactcagat cagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtga ttacatattc ggtgccggga
      421 cccggctcac cgtcccaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000010             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15991:13260
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000010
VERSION     KCWK01000010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15991:13260"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..343
                     /note="immunoglobulin light chain variable region"
     V_region        13..343
     V_segment       13..306
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <268..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65748.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       309..343
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>381
                     /gene="IGLC"
BASE COUNT           70 a          121 c          103 g           87 t
ORIGIN      
        1 acatgggggg cccagtctgt gctgactcag ccaccctcag cgtctggggc tcccgggcag
       61 agtgtcacca tctcttgttc tggaagcatc tccagcattg gaagtagtga tgtatgttgg
      121 taccagcaac tcccaggaac ggcccccaaa ctcctcatca attatagtga tcagcgactc
      181 tcaggggtcc ctgaccgatt ctctggctct aagtctggca cctcagcctc cctggccatc
      241 actggtctcc gatctgagga tgaggctgat tattactgtg cagcctggga tagcagcctg
      301 agcagtccgg tattcggcgg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      361 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000011             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:12986:14979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000011
VERSION     KCWK01000011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12986:14979"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65749.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       398..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          158 c          122 g          102 t
ORIGIN      
        1 acatggggga gcagagccct gaggagtctg caccatggcc tggaccccaa tcctcctcct
       61 cctcctcact ctcctccttc actgcacagg gtctctctcc cagcctgtgc tgactcagtc
      121 gccctctgtc tctgcctccc tgggagcctc ggtcaaactc acctgtactt tgaacagtgg
      181 gcacagcagc tacaccatcg catggcatca gcagcagcaa gggaaggccc cccggtactt
      241 gatgtggctt aaaagtgaag gcagccatag caagggggac gggatccctg atcgcttctc
      301 aggctccagc tccggggctg agcgctacct caccatctcc aacctccagt ctgaggatga
      361 ggctgattat tactgtcaga cctgggatac tgacattgtg ttattcggag gagggactcg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000012             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:19135:17737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000012
VERSION     KCWK01000012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19135:17737"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65750.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       408..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          155 c          119 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatatac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc aggggtctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt gccatcggac acagcagcgg tgattatatc ttcggtgctg
      421 ggacccggct catcgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000013             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:5318:10121
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000013
VERSION     KCWK01000013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5318:10121"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65751.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       393..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>465
                     /gene="IGLC"
BASE COUNT           90 a          145 c          134 g           96 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gactctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtcctggtc
      241 atctatgcta ataacgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt ggggcgttac tagtgatcat cccttattcg gaggagggac ccggctgacc
      421 gtccaaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000014             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:5201:13212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000014
VERSION     KCWK01000014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:5201:13212"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65752.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          156 c          127 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattac tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc ctcctcggtc actctcttcc cg
//
LOCUS       KCWK01000015             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:12599:7374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000015
VERSION     KCWK01000015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12599:7374"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65753.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          157 c          119 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagtcagg gagtcctccc cggtatcttc
      241 taagatacaa atcagactca gatcagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacgggga ttttacacgt ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000016             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:28450:12620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000016
VERSION     KCWK01000016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:28450:12620"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..431
                     /note="immunoglobulin light chain variable region"
     V_region        110..431
     V_segment       110..391
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65754.1"
                     /translation="VYYCQVWDSSSEWLF"
     J_segment       401..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          149 c          136 g           94 t
ORIGIN      
        1 acatgggggc cctgtctggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggcc tcctcgctta ctgcacaggg tctgcgacct cctatgagct
      121 gactcagcca ccctcagtgt cagcggcctc aggacagacg gccaggatca cctgtggggg
      181 agacaacatt ggaactaaaa ctgtgcactg gtaccaacag aaggcagcac aggcccctat
      241 gctggtcatc tttgctgata gcaaacggcc ctcagggatc cctgaccgat tctctggctc
      301 caactcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctgt
      361 ctattactgt caggtgtggg acagtagtag tgagtggctt ttcggcggag ggacccggct
      421 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000017             360 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:13560:10927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000017
VERSION     KCWK01000017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 360)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 360)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..360
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13560:10927"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..322
                     /note="immunoglobulin light chain variable region"
     V_region        7..322
     V_segment       7..285
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <250..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65755.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       288..322
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>360
                     /gene="IGLC"
BASE COUNT           78 a          109 c           95 g           78 t
ORIGIN      
        1 acatgggcat ccccgggagc atcggccaga ctcccctgca ccctgagcag tgacctcagt
       61 gttggtagta aaaacatgta ctggtaccaa cagaagccag ggagcgctcc caggttattc
      121 ctgtactact actccgactc agacaagcag ctgggacctg gggtccccaa tcgagtctct
      181 ggctccaagg agacctcaag taacacagcg tttttgctca tctctgggct ccagcctgag
      241 gacgaggccg attattactg tcaggtgtat gacagtagtg ctaatgtctt attcggagga
      301 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000018             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:24365:9186
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000018
VERSION     KCWK01000018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24365:9186"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65756.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          162 c          112 g          108 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagttacaa atcagactca gataagggcc agggcgctgg agtccccagc cgcttctctg
      301 gatccaaaaa tgcttcaaca aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000019             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:21232:13526
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000019
VERSION     KCWK01000019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21232:13526"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65757.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       390..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           86 a          139 c          135 g          102 t
ORIGIN      
        1 acatggggga ctttgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctttacaggc tctgtggcct cctatgagtt gcctcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctttggggg agacaacatt
      181 ggaagtaata gtgtgcattg gtaccagcag aagccaccgc gggcccctgt attggtcatc
      241 tctgttgata gcgaacggcc ctcagggatc cctgagcgat tctctggttc cagatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg ataatattta taaatacgcg gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000020             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11846:15705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000020
VERSION     KCWK01000020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11846:15705"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65758.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          156 c          126 g          106 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agactccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagaaat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagcgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000021             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:15601:13728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000021
VERSION     KCWK01000021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15601:13728"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65759.1"
                     /translation="DYYCQVWDSTSDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          153 c          130 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccaggg tcacctgtgg gggagacaac
      181 attggaacta cgtttgtcca ctggtaccag cagaatccac cgcaggcccc tgtgcaggtc
      241 atctttgcgg ataacaaacg gccctcaggg atccctgaac gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtac tagtgatcat tacatcttcg gtggtgggac ccgcctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000022             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:16594:3596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000022
VERSION     KCWK01000022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16594:3596"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65760.1"
                     /translation="DYYCQSYDRSLSAVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          154 c          131 g          109 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggcc accatctcct
      181 gcactgggag cagctccaac attggagatt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc cagactcctc atctatgaaa ataataaacg acgctcaggg gcttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctcgctgac cataagtgga ctccagtctg
      361 aggatgaggc tgactattac tgccagtctt atgacagaag cttgagtgct gtgttattcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000023             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:5703:17941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000023
VERSION     KCWK01000023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5703:17941"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65761.1"
                     /translation="DYSCQVWDSESDYYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          144 c          135 g           96 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gggtctgcga cctcctttga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaatta aatttgtcca ctggtaccag cagaagccag cgcaggcccc tgtgaaggtc
      241 atctatgctg atgacaaacg gccctcaggg atccctgaga gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattcc
      361 tgtcaggtgt gggacagtga gagtgattat tacatcttcg gtggtgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000024             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:23202:17420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000024
VERSION     KCWK01000024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23202:17420"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..433
                     /note="immunoglobulin light chain variable region"
     V_region        85..433
     V_segment       85..394
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65762.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       396..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           96 a          150 c          109 g          116 t
ORIGIN      
        1 acatggggaa aagaggctgt gtccaccatg gcctggactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctcgcagcct gtgctgactc agccaacctc cctctcagca
      121 tctcctggag catcagccag actcacctgc accttgaaca gtggcatcag tgttggtaat
      181 tacaggatat tctggtacca ccagaagcca gggagtcctc cccggtatct tctgaactac
      241 cacacagact cagatattca tcaggggtct ggagtcccca gccgcttctc tggatccaaa
      301 gatgcttcgg ccaatgcagg gattttactc atctctggac tccagtctga ggatgaggct
      361 gactattact gtatgatttg gcacaacaat gcttattggg ttttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000025             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:24525:6939
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000025
VERSION     KCWK01000025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24525:6939"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..398
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65763.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       400..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           96 a          151 c          112 g          116 t
ORIGIN      
        1 acatggggca gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctcgca gcctgtgctg actcagccaa cctccctctc
      121 agcatctcct ggagcatcag ccagactcac ctgcaccttg aacagtggca tcagtgttgg
      181 taattacagg atattctggt accaccagaa gccagggagt cctccccggt atcttctgaa
      241 ctaccacaca gactcagata ttcatcaggg gtctggagtc cccagccgct tctctggatc
      301 caaagatgct tcggccaatg cagggatttt actcatctct ggactccagt ctgaggatga
      361 ggctgactat tactgtatga tttggcacaa caatgcttat tgggttttcg gcggagggac
      421 ccggctaacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000026             346 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:3126:15763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000026
VERSION     KCWK01000026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 346)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 346)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:3126:15763"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..308
                     /note="immunoglobulin light chain variable region"
     V_region        7..308
     V_segment       7..271
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <236..>280
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65764.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       274..308
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        309..>346
                     /gene="IGLC"
BASE COUNT           71 a          111 c           92 g           72 t
ORIGIN      
        1 acatgggggg tctccggggc agacggtcac catctcctgt acccgcagca gaggcaacat
       61 tgacaatagt tatgtgcagt ggtaccagca gcgcccgggc agtgccccga ccacagtgat
      121 ttacagagat aaccaaagag cctctggggt ccctgatcgg ttctctggct ccatcgacag
      181 ctcctccaac tctgcctccc tcaccatctc tgggctgaag tctgaggacg aggctgacta
      241 ctactgtcag tctactgatg gcaactacaa tcggttattc ggaggaggga cccggctgac
      301 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000027             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:12082:8048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000027
VERSION     KCWK01000027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:12082:8048"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65765.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          163 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcggg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000028             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:23451:8867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000028
VERSION     KCWK01000028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23451:8867"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65766.1"
                     /translation="DYFCQVWDSGSDHYIF"
     J_segment       388..421
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>463
                     /gene="IGLC"
BASE COUNT           86 a          148 c          132 g           97 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctatgagt tgactcagcc
      121 accctcggtg tcagcggcct ctggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaca tatgtgcact ggtaccagca gaagccacca caggcccctg tgcaggtcat
      241 ctttgctgat agcaaacggc cctcaggggt ccctgaccga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actatttctg
      361 tcaggtgtgg gacagtggta gtgatcatta catcttcggt gttgggaccc ggctcaccgt
      421 cttaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000029             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:13996:16545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000029
VERSION     KCWK01000029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13996:16545"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65767.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          122 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacga tagtgctgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000030             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:5518:5493
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000030
VERSION     KCWK01000030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5518:5493"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..426
                     /note="immunoglobulin light chain variable region"
     V_region        97..426
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65768.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       395..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>465
                     /gene="IGLC"
BASE COUNT           93 a          154 c          114 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctcgt gctctggaag cagctccaac
      181 attggaacta attatgtata ctggtaccaa cacctcccag gaacggcccc caaactcctc
      241 atctattata gtaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattat
      361 tgtgcagcat gggataacag cctgaccagt ccggtattcg gaggagggac ccggctgacc
      421 gtcctaagtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000031             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:11816:13153
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000031
VERSION     KCWK01000031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:11816:13153"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..238
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <202..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65769.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       243..277
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>315
                     /gene="IGLC"
BASE COUNT           79 a           87 c           83 g           66 t
ORIGIN      
        1 acatggggga tcacctgctc tggagaaata ctggcaaaaa aatatactca gtggttccag
       61 cagcagccag gccaggcccc tttcctggtg atatataaag acagtgagag gccctcaggg
      121 atccctgagc gattctctag ctccagttca gggacaacaa ttaccttgac catcagtggg
      181 gcccaggcag aagatgaggc tgactattac tgtcaatcag tagacagcag tggaaatctt
      241 ccgttattcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      301 gtcactctct tcccg
//
LOCUS       KCWK01000032             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:25460:14209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000032
VERSION     KCWK01000032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:25460:14209"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    36..366
                     /note="immunoglobulin light chain variable region"
     V_region        36..366
     V_segment       36..327
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <291..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65770.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       329..366
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>404
                     /gene="IGLC"
BASE COUNT           76 a          125 c          108 g           95 t
ORIGIN      
        1 acatgggtct cattcactgc acagggtcct gggcccagtc tgtgctgacg cagccgccct
       61 cagtgtctgg ggcgcccggg cagagggtca ccatctcctg cactgggagc agctccaaca
      121 ttggaggtta ttatgtgcag tggtaccagc agcttccagg agcggccccc aaactcctca
      181 tctatgaaaa tgataaacga ccctcagggg tttctgatcg attctctggc tcccagtctg
      241 attcctcagc ctccctgacc atcactggac tccagtctga ggatgaggct gattattact
      301 gccagtccta tgacagcagc ttgagtgttg tgttattcgg aggagggacc cggctgaccg
      361 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000033             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:17346:14212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000033
VERSION     KCWK01000033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17346:14212"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..419
                     /note="immunoglobulin light chain variable region"
     V_region        89..419
     V_segment       89..375
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65771.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       389..419
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           86 a          149 c          114 g          108 t
ORIGIN      
        1 acatggggag cgctctcagg acttctccac catggtctgg gctctgctcc tcctcaccct
       61 cctcactcag ggcacaggat cctgggctca ggctgccccg actcagactc cctctgtgtc
      121 cgggtctcct ggacagtcgg tcaccatctc ctgcactgga accagcagtg atattgggta
      181 ttatcatgct gtgtcttggt accagcatca tccaggcaaa gcccccaaac tcatgattta
      241 tgaggtcaat aaacggcccg caggggtctc tgatcgcttc tctggctcca agtctggcaa
      301 cacggcctcc ctgaccatct ctgggctcca gactgaggat gaggctgatt attactgtag
      361 ctcatatgca ggcagcaaca gtttattctt cggaggaggg acccggctga ccgtcctagg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000034             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:17751:13266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000034
VERSION     KCWK01000034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17751:13266"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65772.1"
                     /translation="DYYCQVWDSSTRYAVF"
     J_segment       397..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          147 c          136 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcat tgccagcggc ctcaggacag acggccagga tcgcctgtgg gggagacagc
      181 attggaagtg aaaatgtgtt ctggtaccag cagaagccac ggcaggcccc tgtcctggtc
      241 atctatggtg atacgaaacg gccctcaggg atccctgagc gattctctgg ctccatctct
      301 gggaacaccg ccaccctgac catcaacagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tactagatac gcggttttcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000035             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:13149:3286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000035
VERSION     KCWK01000035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13149:3286"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..408
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65773.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       411..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          164 c          117 g          108 t
ORIGIN      
        1 acatgggggc ccactgcagg gaaagaggct gtgtccacca tggcctggac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac ccagccaacc
      121 tccctctcag catctccggg agcatcagcc agactcagct gcaccttgag cagtggcgtc
      181 aatgtgggta gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac
      241 cttctgtact accagtcaga ctcaaggaaa caccagggct ctggagtccc cagccacttc
      301 tctggatcca aagatgcttc agccaatgca ggactattac tgatctctgg gctccagtct
      361 gaagatgagg ctgactatta ctgtgcccta tggcacagca gcgcttcttg catcttcggt
      421 ggtgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000036             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:10393:17532
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000036
VERSION     KCWK01000036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10393:17532"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65774.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          154 c          121 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccgg gaagagggtc tccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctctcagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagcggt tacatcttcg gtgctgggac ccggctcgcc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000037             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:7580:14889
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000037
VERSION     KCWK01000037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:7580:14889"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65775.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          164 c          124 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagcctc
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagcgggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000038             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:24727:19164
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000038
VERSION     KCWK01000038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24727:19164"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..418
                     /note="immunoglobulin light chain variable region"
     V_region        94..418
     V_segment       94..381
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <343..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65776.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       382..418
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>456
                     /gene="IGLC"
BASE COUNT           93 a          145 c          115 g          103 t
ORIGIN      
        1 acatggggag aagcagaact ctgggtcctc tccaccatgg cctgtacccc tcccctgctc
       61 atcctcctca ctctctgcac aggttccgtg gtttcctctg agctgactca ggagcctgca
      121 ttgtctgtgg ccttgggaca aacagtcagg atgacctgcc aaggagacag cctcaaaacc
      181 tattatgcaa gctggtacca gcagaagcca ggccaggtcc ctgtgctggt catctatggt
      241 aacaactacc ggccctcagg gatcccaggc cgattctctg tctcctggtc aggaaacaca
      301 ggttccttga ccatcactgc ggctcaggtg gaagatgagg ctgactatta ctgtaagtcc
      361 tgggacagca gtggtaccca ttacatcttc ggtgctggga cccggctcac cgtcctaggt
      421 cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000039             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:23491:17063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000039
VERSION     KCWK01000039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23491:17063"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..389
                     /note="immunoglobulin light chain variable region"
     V_region        44..389
     V_segment       44..352
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <317..>361
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65777.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       353..389
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        390..>427
                     /gene="IGLC"
BASE COUNT           84 a          144 c           98 g          101 t
ORIGIN      
        1 acatgggctc ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca
       61 gccaacctcc ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag
      121 tggcaatgtt ggtagttaca gcatattctg gtaccagcag aagccaggga gtcctccccg
      181 gtaccttctt tactactact cagactcaag taaccaccag gactctggag tccccagccg
      241 cttctctgga tcgaaagatg cttcagccaa tgcagggctt ttactgatct ctgggctcca
      301 gtctgaagat gaggctgact attactgtgc cacatggcac agcagcgctt cttacatctt
      361 cggtggtggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      421 gttcccg
//
LOCUS       KCWK01000040             321 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:17468:15205
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000040
VERSION     KCWK01000040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 321)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17468:15205"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..283
                     /note="immunoglobulin light chain variable region"
     V_region        8..283
     V_segment       8..248
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <211..>255
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65778.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       250..283
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>321
                     /gene="IGLC"
BASE COUNT           69 a           94 c           79 g           79 t
ORIGIN      
        1 acatgggcca tctcctgcac tggaaccagc agtgatgttg ggtattataa cgctgtgtct
       61 tggtaccaac agcatccagg caaagccccc aaactcatga tttatgacgt cattaaacgg
      121 ccctcagggg tttctgatcg cttctctggc tccaagtctg gcaacacggc ctccctgacc
      181 atctctgggc tccaggctga ggatgaggct gattattact gcagctcata tgcaggcaga
      241 aataattttt tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      301 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000041             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:18628:10609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000041
VERSION     KCWK01000041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18628:10609"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..391
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65779.1"
                     /translation="DYYCAVWDNSLTSPLF"
     J_segment       398..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           92 a          153 c          115 g          106 t
ORIGIN      
        1 acatggggga cagaaggcag gactcaggat aatctccagc atggcctggt tccctctcgt
       61 cctcaccctc ctcactcact gtgcagggtc ctgggcccag tctgtgctga ctcagccacc
      121 ctcagcgtct gggactcccg ggcagagtgt caccatctct tgctctggaa gcaactccaa
      181 cattggaaat aattatgtat actggtacca gcacctccca ggaacggccc ccaagctcct
      241 catctattat agttatcagc gaccctcagg ggtccctgac cgattctctg gctctaagtc
      301 tggcacctca gcctccctgg ccatcactgg tctccgaact gaggatgagg ctgattatta
      361 ctgtgcagta tgggataaca gcctgaccag tccgttgttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000042             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:10244:4364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000042
VERSION     KCWK01000042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10244:4364"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65780.1"
                     /translation="DYYCSSYAGSNILFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          148 c          121 g          114 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg gtttatgagg tcaataaacg gcccgcaggg gtctctgatt ggttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag taatatttta tttttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000043             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:5057:16140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000043
VERSION     KCWK01000043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5057:16140"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65781.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       414..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          156 c          124 g          109 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccggaca gagggtcacc atctcctgca
      181 ttagcagcag ctccaacatc ggggcggctt attatgtatc ctggtaccaa cagttcccag
      241 gaacagcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctgtgg ctccaagtct ggtccctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattac tgtttagcat gggataccag cctgaattgg atcttcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000044             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:13115:4654
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000044
VERSION     KCWK01000044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13115:4654"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..389
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65782.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       391..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           84 a          149 c          128 g          105 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctctcct
       61 tctcactctg ctggttcact gcacagggtc ctgggcccag tctgtgctga cgcagccgcc
      121 ctcagcatct ggggcccccg ggcagagggt taccatctcc tgcactggga gcagctccaa
      181 catcggggcg ggtttttatg tgtcctggta ccagcagttc cctgggacag cccccaaact
      241 cctcatcttt gaaaataata agcgaccctc aggggtttct gaccgattct ctggctccaa
      301 gtctggttcc tcagcctccc tgaccatcac tggactccag tctgaggatg aggctgatta
      361 ttactgctca tcatgggaaa gcagcctgaa ttgggtattc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000045             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:16270:16530
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000045
VERSION     KCWK01000045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16270:16530"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65783.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          152 c          114 g          116 t
ORIGIN      
        1 acagggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttggtaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcatc aggggtctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000046             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11897:17307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000046
VERSION     KCWK01000046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11897:17307"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..401
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <357..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65784.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       402..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          153 c          133 g           97 t
ORIGIN      
        1 acatgggggc ccatcctggc ttcagaagca gcatctggga catgtcagcc atggcctgga
       61 cgcctctcct cctcagcctc ctcgctcact gcacaggctc tgtggcctcc tatgagctga
      121 ctcagccacc ctcagtgtcg gtgtccccag gacagacagc cagcatcacc tgctctggaa
      181 ataaattggg gaatgtatat gcttactggt tccagcagaa gccaggccag gcccctgtag
      241 tggtcatcta caaagatacc aaccggccct cagggatccc tgagcgattc tctggctccg
      301 actcagggaa cacggccacc ctgaccatca gcagggtcga ggctggggat gaggccgact
      361 atttttgtgc tgcagcctat ggcagtggca gcagctggca gtgggtattc ggcggaggga
      421 cccggctaat cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000047             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:25034:19491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000047
VERSION     KCWK01000047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25034:19491"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..446
                     /note="immunoglobulin light chain variable region"
     V_region        99..446
     V_segment       99..406
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65785.1"
                     /translation="DYFCAIGHSSGDYIF"
     J_segment       413..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          159 c          122 g          114 t
ORIGIN      
        1 acatgggggg cccactgtgg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctatgctga ctcagccggc
      121 ctccttctca gcatctcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat
      181 caatgttgct ggctaccaca tacactggta ccagcagatg ccagggagtc ctccccggtt
      241 tcttctgaga tacaagtcag actcagataa gggccagggc tctggagtcc ccagccgctt
      301 ctctggatcc aaggatgctt cagcgaacac aggaatttta cgcatctctg ggctccagtc
      361 tgaggatgag gctgactatt tctgtgccat tgggcacagc agcggtgatt atatcttcgg
      421 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01000048             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:10478:15602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000048
VERSION     KCWK01000048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10478:15602"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65786.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          138 c          135 g          104 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggaaaga cggccaggat cacctgtggg ggagacaata
      181 ttggaagtga agttgtcaac tggtaccagc agaagccacc gcaggcccct gtggtggtca
      241 tctatgctga ttatgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcggag tcgaggccgg ggatgaggct gactattact
      361 gtcaggtttg ggacatttat attgatcatc cggtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000049             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:19660:11323
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000049
VERSION     KCWK01000049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19660:11323"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..450
                     /note="immunoglobulin light chain variable region"
     V_region        105..450
     V_segment       105..413
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65787.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       414..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           90 a          163 c          124 g          111 t
ORIGIN      
        1 acatggggaa ccctgggtct gtggcctcag aggtagccgt gtccaccatg gccctgactc
       61 ctctcctcct cctgctcctc tctcactgca caggttccct ctcccagcct gtgctgactc
      121 agccaccctc cctgtctgca tccccgggag catcggccag actcccctgc accctgagca
      181 gtgacctcag tgttggtagt aaaaacatgt actggtacca gcagaggcca gggagcgctc
      241 ccaggttatt cctgtattac tactccgact cagacaagca gctgggacct ggggtcccca
      301 atcgagtctc tggctccaag gagacctcag gtaacacagc gtttttgctc atctctggac
      361 tccagcctga ggacgaggcc gattattact gtcaggtgta tgacagtagt gctgtgttat
      421 tcggaggagg gacccgactg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01000050             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20384:10418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000050
VERSION     KCWK01000050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20384:10418"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65788.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          154 c          114 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttggtaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcacc agggctctgg agtccccagc cgcttctctg
      301 ggtccaagga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggta ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000051             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:14563:23292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000051
VERSION     KCWK01000051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14563:23292"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..408
                     /note="immunoglobulin light chain variable region"
     V_region        63..408
     V_segment       63..369
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65789.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       371..408
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           81 a          152 c          110 g          103 t
ORIGIN      
        1 acatgggggc cctgactcct ctcctcctcc tgctcctctc tcactgcaca ggttccctct
       61 cccagcctgt gctgactcag ccaccctccc tgtctgcatc cccgggagca tcggccagac
      121 tcccctgcac cctgagcagt gacctcagtg ttggtagtaa aaacatgtac tggtaccagc
      181 agaagccagg gagcgctccc aggttattcc tgtactacta ctccgactca gacaagcagc
      241 tgggacctgg ggtccccaat cgagtctctg gctccaagga gacctcaagt aacacagcgt
      301 ttttgctcat ctctgggctc cagcctgagg acgaggccga ttatttctgc caggtgtttg
      361 acagtagtgt tgtgttcttc ggaggaggga cccgactgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000052             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:6495:15314
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000052
VERSION     KCWK01000052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6495:15314"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65790.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          158 c          128 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagggtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000053             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:9573:16770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000053
VERSION     KCWK01000053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9573:16770"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65791.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       394..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          141 c          139 g           98 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg tcgggaccct
       61 tctcctcctc ggcctccttg ctcactttac aggctctgcg gcctcctatg cggtgactca
      121 gccacgctca gtgtccgtgt ccccaggaca ggcggccagg atcacctgtg ggggagacaa
      181 cattggaagt aaaagtgtcc agtggtacca gcagacgcca ccgcaggccc ctgtactggt
      241 catttatggt gatagggaac ggccctcagg gatccctgaa cgattctctg gctccaactc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggatagta gtagtaaata tgtcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000054             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:13081:5459
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000054
VERSION     KCWK01000054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13081:5459"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65792.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          152 c          119 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgttgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag caagtcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctctcagtct
      301 ggcacgtcag cctccctggc catcagtggc ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgaggggt tacatcttcg gtgctgggac ccggctcgcc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000055             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:9335:7632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000055
VERSION     KCWK01000055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9335:7632"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65793.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          146 c          132 g           97 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctttga gctgactcag
      121 ccaccctcgg tgtcagtggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaatta aatttgtcca ctggtaccag cagaagccag cgcaggcccc tgtgaaggtc
      241 atctatgctg atgacaaacg gccctcaggg atccctgaga gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattcc
      361 tgtcaggtgt gggacagtga gactgatcat tacatcttcg gtgttgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000056             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:9076:5274
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000056
VERSION     KCWK01000056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:9076:5274"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    33..378
                     /note="immunoglobulin light chain variable region"
     V_region        33..378
     V_segment       33..341
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <309..>350
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65794.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       342..378
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        379..>416
                     /gene="IGLC"
BASE COUNT           83 a          133 c          108 g           92 t
ORIGIN      
        1 acatggggac tcactgcaca ggttccctct cccagcctgt gctgactcag ccaccctccc
       61 tgtctgcatc cccgggagca tcggccagac tcccctgcac cctgagcagt gacctcagtg
      121 ttggtagtaa aaacatgtac tggtaccagc agaggccagg gagcgctccc aggttattcc
      181 tgtattacta ctccgactca gacaagcagc tgggacctgg ggtccccaat cgagtctctg
      241 gctccaagga gacctcaggt aacacagcgt ttttgctcat ctctggactc cagcctgagg
      301 acgaggccga ttattactgt caggtgtatg acagtagtgc tgtgttattc ggaggaggga
      361 cccgactgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000057             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:9216:20005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000057
VERSION     KCWK01000057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9216:20005"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65795.1"
                     /translation="DYYCAMWHSSVYGLF"
     J_segment       404..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          155 c          115 g          115 t
ORIGIN      
        1 acatgggggc tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cgattccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tacttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagtagtgt ttatggctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000058             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11878:13365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000058
VERSION     KCWK01000058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11878:13365"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65796.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          141 c          132 g           96 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgtga cctcctatga attgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000059             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:5507:8919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000059
VERSION     KCWK01000059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5507:8919"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65797.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          156 c          118 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacgtacac tggtatcagc agaagccagg gggtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc tgggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aatacaggga ttttacacat ctctggtttc cagtctgagg
      361 atgaggctga ctattactgt gccattggcc acggcagcgg tgattacatc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000060             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:19481:21388
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000060
VERSION     KCWK01000060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19481:21388"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65798.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          161 c          124 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acgtggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000061             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:23334:15601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000061
VERSION     KCWK01000061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:23334:15601"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65799.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       402..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          160 c          118 g          109 t
ORIGIN      
        1 acatgggggt ggcctcagag gtagccgtgt ccaccatggc cctgactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgattcag ccaccctccc
      121 tgtctgcatc cccgggagca tcggccagac tcccctgcac cctgagcagt gacctcagtg
      181 ttggtaataa aaacatgtac tggtaccaac agaagccagg gagcgctccc aggttattcc
      241 tgtactacta ctccgactca gacaagcagc tgggacctgg ggtccccaat cgagtctctg
      301 gctccaagga gacctcaact aacacagcgt ttttgctcat ctctgggctc cagcctgagg
      361 acgaggccga ttattactgt caggtgtttg acagtagtgc tgtgttgttc ggaggaggga
      421 cccgactgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000062             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:18381:13642
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000062
VERSION     KCWK01000062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18381:13642"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65800.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          157 c          122 g          108 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata atgtgtcctg gtaccagcac ctcccaggaa
      241 cagctcccaa actcctcatc tattataatg atcaacgagg ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcgtggg atgatagcct gagcagttac atcttcgctg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01000063             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:7273:18449
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000063
VERSION     KCWK01000063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7273:18449"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65801.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          162 c          122 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagtcac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000064             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:21076:14046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000064
VERSION     KCWK01000064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:21076:14046"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65802.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          152 c          113 g          116 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcatctcc tggagcatca gccagactca cctgcacctt gagcagtggc ttcagtgttg
      181 gtacttacag gatattctgg taccagcaga agccagggag tcctccccgg tatcttctta
      241 actaccacac agactcagat aagcaccagg actctggagt ccccagccgc ttctttggat
      301 ccaaagatgc ttcggccaat gcagggattt tactcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtatg atttggcaca acaatgctta tgtcttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000065             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:13435:20606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000065
VERSION     KCWK01000065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13435:20606"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65803.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          155 c          126 g          115 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtggtca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggagat ttttatgtgc agtggtacca gcaccttcca
      241 ggaacggccc ccagactcct catctatgaa aataataagc gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tggaacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtttgattgc tgtgttattc
      421 ggaggaggga cccggttgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01000066             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:25077:11180
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000066
VERSION     KCWK01000066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25077:11180"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65804.1"
                     /translation="YYYCSSYAGSHTYIF"
     J_segment       399..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           80 a          163 c          119 g          110 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcaggacgtc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac agggtcctgg gctcaggctg ccctgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggttccag cagcacccag gcaaagcccc
      241 caaactcatg atttatgatg tcactcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaaatct ggctacacgg cctccctgac cgtctctggg ctccaggctg aggatgaggc
      361 ttattattac tgcagctcat atgcaggcag ccacacttac atcttcggtc ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01000067             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:24906:12991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000067
VERSION     KCWK01000067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:24906:12991"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65805.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           89 a          143 c          125 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggcttccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000068             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:23764:14768
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000068
VERSION     KCWK01000068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23764:14768"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65806.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       399..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           95 a          150 c          114 g          115 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcgcag cctgtgctga ctcagccaac ctccctctca
      121 gcatctcctg gagcatcagc cagactcacc tgcaccttga acagtggcat cagtgttggt
      181 aattacagga tattctggta ccaccagaag ccagggagtc ctccccggta tcttctgaat
      241 taccacagag actcagatat tcaccagggc tctggagtcc ccagccgctt ctctgggtcc
      301 aaggatgctt cggccaatgc agggatttta ctcatctctg gactccagtc tgaggatgag
      361 gctgactatt actgtatgat ttggcacaac aatgcttatt gggtattcgg cggagggacc
      421 cggctaaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000069             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:16413:19191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000069
VERSION     KCWK01000069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16413:19191"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65807.1"
                     /translation="DYYCAMWHSSTYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          159 c          112 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcactta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000070             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:14340:6257
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000070
VERSION     KCWK01000070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:14340:6257"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65808.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           93 a          160 c          124 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg acgcagccac
      121 cctccctgtc tgcatccccg ggagcaccgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatgttgg cagtaaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tgtttctgta ctacaactcc gactcagaca agcagcgggg acctggggtc cccaatcgag
      301 tctctggttc caaggagacc tcaagtaaca cagcgttttt gatcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tttatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000071             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:24934:22223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000071
VERSION     KCWK01000071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24934:22223"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65809.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       390..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          138 c          140 g           98 t
ORIGIN      
        1 acatggggcc tgactttggg aagcagcctt ggcggtgcct cagccatggc cgggaccctt
       61 ctcctcctcg gcctccttgc tcactttaca ggctctgcgg cctcctatga ggtgactcag
      121 ccacgctcag tgtccgtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta aaagtgtgca gtggtaccag cagacgccac cgcaggcccc tgtactggtc
      241 atttatggtg atagggaacg gccctcaggg atccctgagc gattctctgg ttccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggatagtag tagtaaatat gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000072             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:22735:14385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000072
VERSION     KCWK01000072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22735:14385"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65810.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          151 c          128 g          116 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc agtatttctt
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctatgaaa atgataaacg accctcaggg atttctgatc
      301 gattctctgg ctcccagtct gattcctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cttgagtgtt gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000073             295 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:5611:13347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000073
VERSION     KCWK01000073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 295)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5611:13347"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..257
                     /note="immunoglobulin light chain variable region"
     V_region        8..257
     V_segment       8..221
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <185..>229
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65811.1"
                     /translation="DYYCCYHTTSGSYIF"
     J_segment       222..257
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>295
                     /gene="IGLC"
BASE COUNT           55 a           98 c           72 g           70 t
ORIGIN      
        1 acatggggac gctgctggtt atacctctgt ctcctggtac caacagcccc caggcaaagc
       61 ccccaaactc atgatttatg gtgtcagtca tcggccctca ggggtctctg atcgcttctc
      121 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      181 ggctgattat tactgttgtt accacacaac cagtggcagt tacatcttcg atggtgggac
      241 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000074             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:28022:11939
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000074
VERSION     KCWK01000074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:28022:11939"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65812.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          149 c          131 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccgatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta agagtgtgca ctggtaccag cacaagccac cgcaggcccc tatcctggtc
      241 atctattatt ataccgaacg gccctcggcg atccctgcgc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacactac tattgatcat ggctttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000075             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:21431:4352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000075
VERSION     KCWK01000075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21431:4352"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..296
                     /note="immunoglobulin light chain variable region"
     V_region        8..296
     V_segment       8..259
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65813.1"
                     /translation="DYYCAIWHSSASYIF"
     J_segment       260..296
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>334
                     /gene="IGLC"
BASE COUNT           67 a          101 c           82 g           84 t
ORIGIN      
        1 acatgggagc tgcaccttga gcagtggcat caatgttggt agttacagct ttttctggta
       61 ccagcagaag ccagggagtc ctccccggta ccttctttac tactactcag agtcaagtaa
      121 ccaccagggc tctggagtcc ccagccgctt ctctggatcc aaagatgctt cagccaatgc
      181 agggctttta ctgatctctg ggctccagtc tgaagatgag gctgactatt actgtgccat
      241 atggcacagc agcgcttctt acatcttcgg tgctgggacc cggctcaccg tcctaggtca
      301 gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000076             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:6893:11901
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000076
VERSION     KCWK01000076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6893:11901"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    77..425
                     /note="immunoglobulin light chain variable region"
     V_region        77..425
     V_segment       77..386
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65814.1"
                     /translation="DYYCAMWHSSVYGLF"
     J_segment       388..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          153 c          107 g          114 t
ORIGIN      
        1 acatggggct gtgtccacca tggcctggac tcctctcctc ctcctgctcc tctctcactg
       61 cacaggttcc ctctcccagc ctgtgctgac ccagccaacc tccctctcag catctccggg
      121 agcatcagcc agactcagct gcaccttgag cagtggcatc aatgttggta gttacagcat
      181 attctggtac cagcagaagc cagggagtcc tccccgattc cttctgtact actactcaga
      241 ctcaaataat caccagggct ctggagtccc cagccgcttc tctggatcca aagatacttc
      301 agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg ctgactatta
      361 ctgtgccatg tggcacagta gtgtttatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000077             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:14931:15960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000077
VERSION     KCWK01000077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14931:15960"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65815.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          148 c          129 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttcttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000078             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:8625:12524
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000078
VERSION     KCWK01000078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8625:12524"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..239
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65816.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       245..277
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>315
                     /gene="IGLC"
BASE COUNT           66 a           91 c           99 g           59 t
ORIGIN      
        1 acatggggga tcacctgcgg gggagacaag attggaagtg aagttgtgaa ctggtaccag
       61 cagaagccag cgcacgcccc tgtgctggtc atctatgcta atagcgaacg gccctcaggg
      121 atccctgagc gattctctgg ctccaaatca gggaacacgg ccaccctgac catcagcggg
      181 gtcgaggccg ggggtgaggc tgactattac tgtcaggtgt gggacatgcg tagtgatcaa
      241 ccgctattcg gcggagggac ccggctaacc gtcctaggtc agcccaaggc tgccccctcg
      301 gtcactctct tcccg
//
LOCUS       KCWK01000079             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:10663:24118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000079
VERSION     KCWK01000079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:10663:24118"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65817.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          146 c          130 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagtc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000080             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:21203:2753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000080
VERSION     KCWK01000080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21203:2753"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65818.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       410..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           89 a          161 c          124 g          107 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cccccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga cgatagcctg cgcggctata tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01000081             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:5528:16443
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000081
VERSION     KCWK01000081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5528:16443"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65819.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          161 c          113 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcacc ctcttcccg
//
LOCUS       KCWK01000082             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:24924:10006
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000082
VERSION     KCWK01000082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24924:10006"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65820.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       385..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           98 a          143 c          120 g           97 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gaagaattgc
      181 caaaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtc cagatcatct
      241 atgaggacag taaacggccc tctgggatcc ctgagagaat ctctggctcc agctcaggga
      301 cagtggccac cttgactatc actggggccc aggtggagga tgaagctgac tactactgtt
      361 tctcaacaga caccagtggt aatcgggtat tcggcggagg gacccgtcta accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000083             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:17056:8466
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000083
VERSION     KCWK01000083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17056:8466"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65821.1"
                     /translation="YYYCSSYAGSHTYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           80 a          164 c          120 g          111 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacagggtcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggttc cagcagcacc caggcaaagc
      241 ccccaaactc atgatttatg atgtcactca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctggctaca cggcctccct gaccgtctct gggctccagg ctgaggatga
      361 ggcttattat tactgcagct catatgcagg cagccacact tacatcttcg gtcctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000084             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:20035:17289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000084
VERSION     KCWK01000084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20035:17289"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65822.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcggctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000085             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:11641:12146
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000085
VERSION     KCWK01000085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:11641:12146"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65823.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          142 c          133 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ttctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaggccaccg caggcccctg tgctgctcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgaccga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000086             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:19918:10269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000086
VERSION     KCWK01000086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19918:10269"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65824.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          156 c          118 g          108 t
ORIGIN      
        1 acatgggggg gatctcacga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct atgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtcc ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcgggg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000087             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:15977:3454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000087
VERSION     KCWK01000087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15977:3454"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..396
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65825.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           94 a          160 c          113 g          107 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctct
      121 gcatctcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 gcctaccaca tacactggta ccagcagaag ccagggagtc ctccccggta tcttctgaga
      241 tacaaatcag actcagataa ggaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgcct cagcgaacac aggaatttta cgcatctctg ggctccagtc tgaggatgag
      361 gctgactact actgtgccat tgggcacagc agcggtgatt acattttcgc tgctgggacc
      421 cgcctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000088             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:25259:10241
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000088
VERSION     KCWK01000088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:25259:10241"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65826.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          142 c          137 g          100 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggttctgcgg cctcctatga tctgactcag
      121 ccaccctcga tttcagcgtc cccaggacag acggccaggg tcacctgtgg gggagacaac
      181 atcggaggtg aagttgtgaa ttggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atctatggtg atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacgcgg ccaccctgac catcagcggg gtcgaggccg gagatgaggc tgactattac
      361 tgtcaggtgt gggaccttaa tagtcatcat ctcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000089             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:16862:15963
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000089
VERSION     KCWK01000089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16862:15963"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65827.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          144 c          142 g           93 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag cggaagccag cgcaggcccc tgtgctggtc
      241 atctatgctg atagcgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg ggggtgaggc tgactattac
      361 tgtcaggtgt gggacatgcg tagtgatcaa ccgctattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000090             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:8253:18425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000090
VERSION     KCWK01000090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8253:18425"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..227
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65828.1"
                     /translation="DYYCQVWDSDSKWIF"
     J_segment       231..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           68 a           85 c           90 g           58 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaactaa aaatgtgcac tggtaccagc agaagccagc
       61 gcagggccct gtattggtca tgtttgctga taccagacgg ccctcaggga tccctgaccg
      121 attctctggc tccaactcag ggaacaccgc caccctgacc atcagcaggg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggacagtgat agtaaatgga tattcggcgg
      241 agggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01000091             323 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:23062:9621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000091
VERSION     KCWK01000091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 323)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23062:9621"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..285
                     /note="immunoglobulin light chain variable region"
     V_region        8..285
     V_segment       8..248
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <204..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65829.1"
                     /translation="DYFCAAAYGSGSTWQWVF"
     J_segment       249..285
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>323
                     /gene="IGLC"
BASE COUNT           65 a           96 c           95 g           67 t
ORIGIN      
        1 acatgggcag catcacctgc tctggaaata aattggggag tgtctatgct tactggttcc
       61 agcagaagcc aggccaggcc cctgtagtgg tcatctacaa agataccaac cggccctcag
      121 ggatccctga gcgattctct ggctccgact cagggaacac ggccaccctg accatcagca
      181 gggtcgaggc tggggatgag gccgactatt tttgtgctgc agcctatggc agtggcagca
      241 cttggcagtg ggtattcggc ggagggaccc ggctaatcgt cctaggtcag cccaaggctg
      301 ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000092             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:16340:18666
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000092
VERSION     KCWK01000092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:16340:18666"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65830.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       410..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          162 c          118 g          110 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 caatattggc aataaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaagtt
      241 attcctgtac tactactccg actcagacat gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtcatac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtatgacagt agtgctgtat tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01000093             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:11251:4412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000093
VERSION     KCWK01000093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11251:4412"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..449
                     /note="immunoglobulin light chain variable region"
     V_region        113..449
     V_segment       113..406
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65831.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       412..449
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           95 a          158 c          122 g          112 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct ctccttctca ctctgctggt tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag catctggggc ccccgggcag agggtcacca tctcctgcac
      181 tgggagcagc tccaacatcg gggcgggtta ttatgtatcc tggtaccagc agttcccagg
      241 aacagccccc aaactcctca tctatgaaaa taataaacga ccctcagggg tttctgaccg
      301 attctctggc tccaagtctg gtacctcagc ctccctgacc atcactggac tccaatctga
      361 ggatgaggct gattattact gctcagcatg ggatagcagc ctgagtatca attacatctt
      421 cggttctggg acccgtctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      481 gttcccg
//
LOCUS       KCWK01000094             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:13331:15863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000094
VERSION     KCWK01000094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13331:15863"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65832.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           96 a          160 c          111 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcaactcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ttgcctacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 gttacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaaaatgc ttcaacaaac acaggcattt tacacatctc tgggctccag tctgaggatg
      361 aggctgacta tttctgtgcc attggacaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000095             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13886:6978
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000095
VERSION     KCWK01000095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13886:6978"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65833.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           90 a          160 c          120 g          110 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggaa ataaaaacat atactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtcataca gcgtttttgc tcatttctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcaggtg tatgacgata gtgctgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000096             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:22030:8127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000096
VERSION     KCWK01000096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22030:8127"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..254
                     /note="immunoglobulin light chain variable region"
     V_region        8..254
     V_segment       8..221
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <177..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65834.1"
                     /translation="DYHCSAGFGSGYSWQWVF"
     J_segment       222..254
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>296
                     /gene="IGLC"
BASE COUNT           59 a           88 c           89 g           60 t
ORIGIN      
        1 acatgggggg gaatgtttat gcttattggt accagcagaa gccaggccag gcccctatac
       61 tggtcatcta caaagatagc aaccggccct cagggatccc tgaccgattc tctggctcca
      121 actcagggaa cacggccacc ctgaccatca gcagggtcga ggctggggat gaggccgact
      181 atcactgttc tgcaggcttt ggcagtgggt acagctggca gtgggttttc ggcggaggga
      241 cccggctaac cgtcgtaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000097             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:25532:12886
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000097
VERSION     KCWK01000097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:25532:12886"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..425
                     /note="immunoglobulin light chain variable region"
     V_region        95..425
     V_segment       95..388
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65835.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       389..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          155 c          119 g          101 t
ORIGIN      
        1 atggggacag aaggcaggac tcaggacaat ctccagcatg gcctggtccc ctctcgtcct
       61 caccctcctc actcactgtg cagggtcctg ggcccagtct gtgctgactc agcctccctc
      121 agcgtctgag gccgccagga agagtgtcac catctcctgt tctggaggca cctccaacat
      181 cggaagtaat agtgtatcct ggtaccagca gctcccagga acagctccca aactcctcat
      241 ctattatagt gatcaacgag cctcaggtgt ctctggccga ttctctggct ccaagtctgg
      301 cacgtcagcc tccctggcca tcagcgggct ccagaccgag gatgaggctg attattactg
      361 cgcagcctgg gatgatagcc tgagcggtta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000098             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:11029:7444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000098
VERSION     KCWK01000098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11029:7444"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..428
                     /note="immunoglobulin light chain variable region"
     V_region        103..428
     V_segment       103..393
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65836.1"
                     /translation="DYYCQSADGNYRVF"
     J_segment       394..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>467
                     /gene="IGLC"
BASE COUNT           85 a          162 c          120 g          100 t
ORIGIN      
        1 acatgggggt ctcagaaagc agagcctggg gcgtctccac catggcctgg gctccactcc
       61 tcctcaccct cctcgctcac tgcacagggt cttgggctga acttgtgttc actcagcccc
      121 attctgtgtc ggggtctccg gggcagacgg tcaccatctc ctgcacccgc agcattggca
      181 acattgacag tgaatatgtg cagtggtacc agcagcgccc gggcagtgcc cccaccacac
      241 tgatttacaa agatagtcaa agaccctctg gggtccctga ccggttctct ggctccatcg
      301 acagctcctc caactctgcc tccctcgcca tctctgggct acagtctgag gacgaggctg
      361 actactactg tcagtctgct gatggcaact acagggtctt cggcggaggg acccggctaa
      421 ccgtcctaag tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000099             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:22431:12471
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000099
VERSION     KCWK01000099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22431:12471"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65837.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          140 c          134 g          101 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggagga gacaacattg
      181 gaagtgaagt tgtcaactgg taccagcaga ggccaccgca ggcccctgtg gtggtcatct
      241 atgctgatta tgaacggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acacggccac cctgaccatc agcggagtcg aggccgggga tgaggctgac tattattgtc
      361 aggtgtggga catttatatt gaccatccgg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000100             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:12825:23000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000100
VERSION     KCWK01000100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12825:23000"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..388
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65838.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       395..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           84 a          156 c          115 g          115 t
ORIGIN      
        1 acatggggga tctcaggagg cagcgctctc aggacttctc caccatggtc tgggctctgc
       61 tcctcctcac cctcctcact cagggcacag gatcctgggc tcaagctgcc ccgactcagc
      121 ctccctctgt gtccgggtct cctggacagt cggtcacctt ctcctgcact ggaaccggca
      181 gtgattttgg gtcttataat gctgtgtctt ggtaccaaca gcatccaggc aaagcccccc
      241 aactcataat ttttgaggtc aataagcggc cctcaggggt ctctgatcgc ttctctggct
      301 ccaagtctgg caacacggcc tccctgacca tctctgggct ccaggctgag gatgaggctg
      361 attattactg ctgctcatat gtaggcagca acacttacat cttcgatgtt gggacccggc
      421 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000101             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:9388:7559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000101
VERSION     KCWK01000101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9388:7559"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..295
                     /note="immunoglobulin light chain variable region"
     V_region        8..295
     V_segment       8..254
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <220..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65839.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       258..295
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        296..>333
                     /gene="IGLC"
BASE COUNT           71 a          102 c           83 g           77 t
ORIGIN      
        1 acatggggga agagtgtcac catctcctgt tctggaagca gctccaacat cggaagtaat
       61 aatgtgtcct ggtaccagca cctcccagga acagctccca aactcctcat ctattataat
      121 gatcaacgag gctcaggtgt ctctgaccga ttctctggct ccaagtctgg cacgtcagcc
      181 tccctggcca tcagtgggct ccagaccgag gatgaggctg attattactg cgcagcgtgg
      241 gatgatagcc tgagtagtta catcttcgct gctgggaccc ggctcaccgt cctaggtcag
      301 cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000102             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:10208:16807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000102
VERSION     KCWK01000102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10208:16807"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65840.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          157 c          117 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacatacac tggtaccagc agaagccagg gagtcctccc cgatatcttc
      241 tgagatacaa atcggactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000103             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:6562:14282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000103
VERSION     KCWK01000103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:6562:14282"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65841.1"
                     /translation="DYYCHVYDNSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          163 c          119 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctatgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atttactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgcg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacaa tagtactaat gtgttattcg
      421 gaggagggac ccgtgtgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000104             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:16551:14088
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000104
VERSION     KCWK01000104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16551:14088"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65842.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       399..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           94 a          152 c          115 g          111 t
ORIGIN      
        1 acatggggct ctggagccag ggatcccttc caatatcagc accatggcct ggactctgct
       61 cctcctccag ttcctcctca cttgctgccc agggtccaat tctcaggctg tagtgactca
      121 ggagccctca atgactgttt ccccaggagg gacagtcact ctcacctgtg cttccagcac
      181 tggagcagtc accagtggtc actctccaca ctggttccag cagaaacctg gacaagcccc
      241 caagacactg atttataata caaactacag acactcctgg actcctgccc ggttctcagg
      301 ctccctcctt gggggtaaag ctgccctgac actgtcaggt gcgcagcctg aggatgaggc
      361 tgagtattat tgtttactgt actatagtgg tgctcagctg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000105             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:5239:15331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000105
VERSION     KCWK01000105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:5239:15331"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65843.1"
                     /translation="DYYYYSADSSGNWVF"
     J_segment       386..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           95 a          136 c          122 g          107 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatagcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctcttcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 accaaaaaaa tatgcttctt ggttccagct gaagccaggc cagtcccctg tgatggtcat
      241 ctttgaggac agcaaacggc cctctgggat ccctgagaga ttctttggct ccagtttagg
      301 gacagtggcc accttgacta taattggggc ccaggtggag gatgaagatg actactacta
      361 ttactcagca gacagtagtg gtaattgggt attcgccgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000106             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:18484:19748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000106
VERSION     KCWK01000106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18484:19748"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65844.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          164 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg acctggggtc cccactcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000107             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:13291:7601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000107
VERSION     KCWK01000107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13291:7601"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65845.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          143 c          134 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggtcagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtcaa ctggtaccaa cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgacc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgcggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tactgatcat ccggtgttgt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000108             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16100:8080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000108
VERSION     KCWK01000108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16100:8080"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..278
                     /note="immunoglobulin light chain variable region"
     V_region        5..278
     V_segment       5..241
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <206..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65846.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       242..278
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>316
                     /gene="IGLC"
BASE COUNT           69 a           99 c           77 g           71 t
ORIGIN      
        1 acatgggggc atcaatgttg ctgcctacca catacactgg taccagcaga agccagggag
       61 tcccccccgg tatcttctga gttacaaatc agactcagat aagggccagg gctctggagt
      121 ccccagccgc ttctctggat ccaaaaatgc ttcaacgaac acaggcattt tacacatctc
      181 tgggctccag tctgaggatg aggctgacta tttctgtgcc attggacaca gcagcggtcc
      241 ttacatcttc ggtgctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac
      301 ggtcactctg ttcccg
//
LOCUS       KCWK01000109             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:24430:13904
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000109
VERSION     KCWK01000109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:24430:13904"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65847.1"
                     /translation="DYHCQVFDSSDVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          161 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tgataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctacttctcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtttgacag tagtgatgtt ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000110             281 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:6486:17095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000110
VERSION     KCWK01000110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 281)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6486:17095"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..243
                     /note="immunoglobulin light chain variable region"
     V_region        8..243
     V_segment       8..206
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <171..>215
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65848.1"
                     /translation="DYYCAMWHSSASYFF"
     J_segment       207..243
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        244..>281
                     /gene="IGLC"
BASE COUNT           56 a           92 c           67 g           66 t
ORIGIN      
        1 acatgggcca gcagaagcca gggagtcctc cccgatacct tctgtactac tactcagact
       61 caagtaaaca ccagggctct ggagtcccca gccgcttctc tggatccaaa gatgcttcgg
      121 ccaatgcagg ccttttactg atctctgggc tccagtctga agatgaggct gactattact
      181 gtgccatgtg gcacagcagc gcttcttact tcttcggtac tgggacccgg ctcaccgtcc
      241 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01000111             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:11353:18028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000111
VERSION     KCWK01000111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11353:18028"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65849.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       403..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          157 c          121 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca cgaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtggccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tccggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttgttcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000112             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:20057:11472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000112
VERSION     KCWK01000112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20057:11472"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65850.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          163 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcggaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000113             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:19248:14020
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000113
VERSION     KCWK01000113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19248:14020"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65851.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          148 c          130 g           95 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgcccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000114             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:17054:18186
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000114
VERSION     KCWK01000114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17054:18186"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65852.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          162 c          114 g          110 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc atcagtgttg
      181 gtacttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctgt
      241 actaccactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcaggtctgt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttgcatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000115             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:12824:10213
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000115
VERSION     KCWK01000115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12824:10213"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65853.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          160 c          111 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gttgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000116             518 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12298:8310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000116
VERSION     KCWK01000116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 518)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 518)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..518
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12298:8310"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    150..480
                     /note="immunoglobulin light chain variable region"
     V_region        150..480
     V_segment       150..443
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <405..>452
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65854.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       444..480
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        481..>518
                     /gene="IGLC"
BASE COUNT          100 a          158 c          143 g          117 t
ORIGIN      
        1 acatggggga gagtatgaag agagggagag atttgggtga agcgcagctt cagctgtggg
       61 tacagaaggc aggactcagg acaatctcca gcatggcctg gttccctctc gtcctcaccc
      121 tcctcactca ctgtgcaggg tcctgggccc agtctgtgct gactcagcct ccctcagcgt
      181 ctgaggccgc caggaagagt gtctccatct cctgttctgg aagcagctcc aacatcggaa
      241 gtcatagtgt ctcctggtac cagcagctcc caggaacagc tcccaaactc ctcatctatt
      301 atagtgatca acgagcctca ggtgtctctg accgattctc tggctctcag tctggcacgt
      361 cagcctccct ggccatcagt gggctccagg ccgaggatga ggctgattat tactgcgcag
      421 catgggatga tagtctgagc ggttacatct tcggtgctgg gacccggctc gccgtcctag
      481 gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01000117             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10700:16287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000117
VERSION     KCWK01000117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10700:16287"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..387
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65855.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       392..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT          106 a          136 c          122 g          100 t
ORIGIN      
        1 acatgggggg tggttctagg aggaagagct ctgggtgtct caccatgacc tggaccactg
       61 ttctgctccc ctttctcact ctctgcacag gctctgaggc ctcctatgag ctgacacagc
      121 caccctcagt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagaaatac
      181 tggcaaaaaa atatactcag tggttccagc agcagccagg ccaggcccct ttcctggtga
      241 tatataaaga cagtgagagg ccctcaggga tccctgagcg attctctagc tccagttcag
      301 ggacaacaat taccttgacc atcagtgggg cccaggcaga agatgaggct gactattact
      361 gtcaatcagt agacagcagt ggaaatcttc cgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000118             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:23619:9884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000118
VERSION     KCWK01000118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:23619:9884"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..432
                     /note="immunoglobulin light chain variable region"
     V_region        87..432
     V_segment       87..395
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65856.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       396..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           92 a          158 c          110 g          110 t
ORIGIN      
        1 acatgggagg gaaagaggct gtgtccacca tggcctggac tcctctcctc ctcctgctcc
       61 tctctcactg cacaggttcc ctctcccagc ctgtgctgac ccagccaacc tccctctcag
      121 catctccggg agcatcagcc agactcagct gcaccttgag cagtggcaat gttggtagtt
      181 acagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt ctttactact
      241 actcagactc aagtaaccac caggactctg gagtccccag ccgcttctct ggatcgaaag
      301 atgcttcagc caatgcaggg cttttactga tctctgggct ccagtctgaa gatgaggctg
      361 actattactg tgccacatgg cacagcagcg cttcttacat cttcggtggt gggacccggc
      421 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000119             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15966:14153
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000119
VERSION     KCWK01000119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15966:14153"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65857.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       404..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          153 c          117 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcttc tcctggagca tcagccagac tcacctgcac cttgagcagt ggcatcagtg
      181 ttggtactta caggatattc tggtaccagc agaggccagg gagtcctccc cggtatcttc
      241 tgaaccacca cacagactca gataaacatc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttgctcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttatgtgtta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000120             517 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:27395:15793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000120
VERSION     KCWK01000120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 517)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:27395:15793"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    149..479
                     /note="immunoglobulin light chain variable region"
     V_region        149..479
     V_segment       149..442
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <404..>451
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65858.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       443..479
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        480..>517
                     /gene="IGLC"
BASE COUNT          101 a          158 c          141 g          117 t
ORIGIN      
        1 acatggggag agtatgaaga gagggagaga tttgggtgaa gcgcagcttc agctgtgggt
       61 acagaaggca ggactcagga caatctccag catggcctgg ttccctctcg tcctcaccct
      121 cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagcctc cctcagcgtc
      181 tgaggccgcc aggaagagtg tctccatctc ctgttctgga agcagctcca acatcggaag
      241 tcatagtgtc tcctggtacc agcagctccc aggaacaact cccaaactcc tcatctatta
      301 tagtgatcaa cgggcctcag gtgtctctga ccgattctct ggctctcagt ctggcacgtc
      361 agcctccctg gccatcagtg gactccaggc cgaggatgag gctgattatt actgcgcagc
      421 atgggatgat agtctgagcg gttacatctt cggtgctggg acccggctcg ccgtcctagg
      481 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01000121             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:8615:14055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000121
VERSION     KCWK01000121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:8615:14055"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..436
                     /note="immunoglobulin light chain variable region"
     V_region        91..436
     V_segment       91..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65859.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           93 a          161 c          110 g          110 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgacccagcc aacctccctc
      121 tcagcatctc cgggaacatc agccagactc agctgcacct tgagcagtgg caatgttggt
      181 agttacagca tattctggta ccagcagaag ccagggagtc ctccccggta ccttctttac
      241 tactactcag actcaagtaa ccaccaggac tctggagtcc ccagccgctt ctctggatcg
      301 aaagatgctt cagccaatgc agggctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccac atggcacagc agcgcttctt acatcttcgg tcctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000122             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:13469:4813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000122
VERSION     KCWK01000122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13469:4813"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..443
                     /note="immunoglobulin light chain variable region"
     V_region        115..443
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65860.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>483
                     /gene="IGLC"
BASE COUNT           87 a          161 c          125 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagcc gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 tcagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccacgtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 cctgggaccc ggctcaccgt cctgggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000123             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:21732:10303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000123
VERSION     KCWK01000123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21732:10303"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65861.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          155 c          128 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctatgaaa atgataaacg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct gattcctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cttgagtgtt gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000124             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:18910:8903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000124
VERSION     KCWK01000124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18910:8903"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..449
                     /note="immunoglobulin light chain variable region"
     V_region        101..449
     V_segment       101..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65862.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       415..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           91 a          164 c          125 g          107 t
ORIGIN      
        1 acatgggggg gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagcactga
      181 cctcagtgtt ggtggtaaaa acatgtactg gtaccagcag aagccaggaa gcgctcccag
      241 gttattgctg tattaccact ccgactcaga caagcagctg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt attactgtca ggtgtatgac agtagtgcca acacgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01000125             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10374:17352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000125
VERSION     KCWK01000125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10374:17352"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65863.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       397..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           86 a          162 c          121 g          102 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgtct ctgcctccct gggagcctcg gtcaaactca cctgcactct gaacagtggg
      181 cacagcagct acaccatcgc atggcatcag catcagcaag ggaaggcccc ccggtacttg
      241 atgtggctta aaagtgatgg cagccatagc ccgggggacg ggatccctga tcgcttttca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatact gacattgtgt tgttcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000126             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:17940:7028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000126
VERSION     KCWK01000126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17940:7028"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..425
                     /note="immunoglobulin light chain variable region"
     V_region        80..425
     V_segment       80..388
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65864.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       389..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          158 c          104 g          112 t
ORIGIN      
        1 acatggggag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc tcctctctca
       61 ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct cagcatctcc
      121 gggaacatca gccagactca gctgcacctt gagcagtggc aatgttggta gttacagcat
      181 attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact actattcaga
      241 ctcaagtaat caccaggact ctggagtccc cagccgcttc tctggatcga aagatgcttc
      301 agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg ctgactatta
      361 ctgtgccaca tggcacagca gcgcttctta catcttcggt cctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000127             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:4159:11633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000127
VERSION     KCWK01000127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4159:11633"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65865.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          162 c          119 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg accttgggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000128             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:15007:4010
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000128
VERSION     KCWK01000128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15007:4010"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65866.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           97 a          162 c          112 g          109 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcaa ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctgcct accacataca ctggtaccag cagaagccag ggagtccccc ccggtatctt
      241 ctgagttaca aatcagactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaaa atgcttcaac aaacacaggc attttacaca tctctgggct ccagtctgag
      361 gatgaggctg actatttctg tgccattgga cacagcagcg gtccttacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000129             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:29651:11950
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000129
VERSION     KCWK01000129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:29651:11950"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65867.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          137 c          133 g          104 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggaaagacgg ccaggatcac ctgtggggga gacaatattg
      181 gaagtgaagt tgtcaactgg taccagcaga agccaccgca ggcccctgtg gtggtcatct
      241 atgctgatta tgaacggtcc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acacggccac cctgaccatc agcggagtcg aggccgggga tgaggctgac tattactgtc
      361 aggtttggga catttatatt gatcatccgg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000130             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:21718:5273
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000130
VERSION     KCWK01000130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21718:5273"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65868.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           91 a          143 c          134 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca gactctgcga cctcctatga attgactcag
      121 tcgccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacgac
      181 attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tctattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgggc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaagcgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000131             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:6999:16148
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000131
VERSION     KCWK01000131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6999:16148"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65869.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           87 a          143 c          135 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctttga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaggccac cgcaggcccc tgtgctggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgacc gattctctgg ctccaagtca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000132             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:9219:5819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000132
VERSION     KCWK01000132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9219:5819"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65870.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          156 c          128 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacggg cctcgggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000133             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:9648:2196
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000133
VERSION     KCWK01000133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9648:2196"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65871.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       411..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          156 c          128 g          113 t
ORIGIN      
        1 acatgggggg ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcacctccaa cattggaggt tattatgtgc agtggtacca gcagcttcca
      241 ggaacggccc ccaaactcct catctatgaa aatgataaac gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tgattcctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gcttgagtgt tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01000134             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:11244:10526
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000134
VERSION     KCWK01000134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11244:10526"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    131..394
                     /note="immunoglobulin light chain variable region"
     V_region        131..394
     V_segment       131..358
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <322..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65872.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       362..394
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>432
                     /gene="IGLC"
BASE COUNT           88 a          133 c          121 g           90 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga actgactcag
      121 tcaccctcag tcacctgtgg gggagacaac attggaatta aaactgtaca ctggtaccag
      181 cagaagccac cgcagggccc tgtattggtc atctttgctg atagtaagcg gcccacaggg
      241 atccctgagc gattctctgg ctccaactca gggaacaccg ccaccctgac catcagcagg
      301 gtcgaggccg gggatgaggc tgactattac tgtcaggtgt gggacagtag tagtaaatgg
      361 atattcggcg gggggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      421 actctcttcc cg
//
LOCUS       KCWK01000135             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:2359:17068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000135
VERSION     KCWK01000135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:2359:17068"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..423
                     /note="immunoglobulin light chain variable region"
     V_region        105..423
     V_segment       105..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65873.1"
                     /translation="DYYCQVWDSDSKWVF"
     J_segment       390..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>464
                     /gene="IGLC"
BASE COUNT           91 a          147 c          136 g           90 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc agtgtcagcg gcctcaggac agacggccag gatcacctgt ggcggggaca
      181 gccttggaac aaaatatgtg cactggtacc agcagaagcc aacgcaggcc cctgtggtgg
      241 tcatctatgc tgataataaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt gatagtaagt gggtcttcgg cggagggacc cggctaaccg
      421 tcccaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000136             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:8713:3780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000136
VERSION     KCWK01000136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8713:3780"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65874.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          158 c          116 g          112 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataaggacc agggctctgg agtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tctttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000137             348 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:10339:16644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000137
VERSION     KCWK01000137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 348)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10339:16644"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..310
                     /note="immunoglobulin light chain variable region"
     V_region        8..310
     V_segment       8..274
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <238..>282
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65875.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       275..310
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        311..>348
                     /gene="IGLC"
BASE COUNT           82 a          101 c          100 g           65 t
ORIGIN      
        1 acatgggcac cctcagtgtc agcggcctca ggacagacgg ccaggatcac ctgtggcgga
       61 gacaacattg gaattaaaaa tgtccactgg taccagcaga agccagcaca ggcccctgtg
      121 gtagtcatct atgctgataa caaacggccc tcagggatcc ctgagcgact ctctggctcc
      181 aactcaggga atattgccac cctgaccatc agcagggtcg aggccgggga tgaggcagac
      241 tattactgtc aggtgtggga cagtagtagt aaatgggtat tcggcggagg gacccggcta
      301 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000138             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:15401:16853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000138
VERSION     KCWK01000138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15401:16853"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65876.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          143 c          132 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaatta aaactgtaca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtaagcg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000139             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:5673:19753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000139
VERSION     KCWK01000139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:5673:19753"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65877.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          162 c          122 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaatgctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000140             314 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:6955:10543
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000140
VERSION     KCWK01000140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 314)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6955:10543"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..276
                     /note="immunoglobulin light chain variable region"
     V_region        6..276
     V_segment       6..236
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <204..>248
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65878.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       239..276
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        277..>314
                     /gene="IGLC"
BASE COUNT           67 a           97 c           80 g           70 t
ORIGIN      
        1 acatgggcat caatgttgct gcctaccaca tacattggta ccagcagaag ccagggagtc
       61 ctccccggta tcttctgaga tataaatcag actcagataa ggaccagggc tctggagtcc
      121 ccagccgctt ctctggatcc aaagatgcct cagcgaacac ggggcttttg cacatctctg
      181 ggctccagtc tgaggatgag gctgactact actgtgccat tgggcacagc agcggtgatt
      241 acatcttcgg tgctgggacc cgcctcaccg tcctaggtca gcccaaggct tcccccacgg
      301 tcactctgtt cccg
//
LOCUS       KCWK01000141             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:12292:18838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000141
VERSION     KCWK01000141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12292:18838"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..440
                     /note="immunoglobulin light chain variable region"
     V_region        110..440
     V_segment       110..401
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65879.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       410..440
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           93 a          155 c          122 g          108 t
ORIGIN      
        1 acatgggggg cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctctc cttctcactc tgctggttca ctgcacaggg tcctgggccc agtctgtgct
      121 gacgcagccg ccctcagcat ctggggcccc cggacagagg gtcaccatct cctgcattag
      181 cagcagctcc aacatcgggg cggcttatta tgtatcctgg taccaacaat tcccaggaac
      241 agcccccaaa ctcctcatct ttgaaaataa taagcgaccc tcaggggttt ctgaccgatt
      301 ctctggctcc aagtctggtc cctcagcctc cctgaccatc actggactcc aatctgagga
      361 tgaggctgat tattactgtt tagcatggga taccagcctg aattggatct tcggcggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000142             329 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:19805:14627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000142
VERSION     KCWK01000142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 329)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19805:14627"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..291
                     /note="immunoglobulin light chain variable region"
     V_region        8..291
     V_segment       8..254
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65880.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       255..291
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>329
                     /gene="IGLC"
BASE COUNT           69 a           99 c           82 g           79 t
ORIGIN      
        1 acatggggag ggtcaccatc tcctgcactg ggagcagctc caacattgga gattattatg
       61 tgcagtggta ccagcacctt ccaggaacgg cccccagact cctcatctat gaaaataata
      121 agcgaccctc aggggtttct gatcgattct ctggctccca gtctggaacc tcagcctccc
      181 tgaccatcac tggactccag tctgaggatg aggctgatta ttactgccag tcctatgaca
      241 gcagtttgat tgctgtgtta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      301 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000143             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:4536:13346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000143
VERSION     KCWK01000143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4536:13346"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65881.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       417..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           95 a          157 c          124 g          109 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg acagagggtc accatctcct
      181 gcattagcag cagctccaac atcggggcgg cttattatgt atcctggtac caacagttcc
      241 caggaacagc ccccaaactc ctcatctatg aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtccct cagcctccct gaccatcact ggactccaat
      361 ctgaggatga ggctgattat tactgtttag catgggatac cagcctgaat tggatcttcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000144             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:20820:19199
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000144
VERSION     KCWK01000144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20820:19199"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..407
                     /note="immunoglobulin light chain variable region"
     V_region        87..407
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65882.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       372..407
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>446
                     /gene="IGLC"
BASE COUNT           91 a          141 c          117 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcgctttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aagatcacct gctctggaga tgcactgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcgat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gcagtggtta tggcttattc ggaggaggga cccggctgac cgtcctacgt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000145             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:5460:17944
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000145
VERSION     KCWK01000145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:5460:17944"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65883.1"
                     /translation="DYFCAAWDDSLTGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          158 c          122 g          109 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcctcctc accctcctca ctcactgtgc agggtccagg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaaccag ctccaacatc ggaagtaata gtgtgtcctg gtaccagcag ctcccagaaa
      241 cggctcccaa actcctcatc tattataatc atcggcgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttatttctgc gcagcatggg atgatagcct gaccggttac attttcggta
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01000146             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10796:6996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000146
VERSION     KCWK01000146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10796:6996"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65884.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          161 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatagag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000147             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:3983:6509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000147
VERSION     KCWK01000147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:3983:6509"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65885.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          162 c          122 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agtagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000148             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:7075:2668
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000148
VERSION     KCWK01000148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7075:2668"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65886.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           93 a          159 c          111 g          110 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatacttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt ggtgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000149             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:3109:12049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000149
VERSION     KCWK01000149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:3109:12049"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..275
                     /note="immunoglobulin light chain variable region"
     V_region        8..275
     V_segment       8..237
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <200..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65887.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       239..275
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>313
                     /gene="IGLC"
BASE COUNT           69 a           94 c           87 g           63 t
ORIGIN      
        1 acatgggatc acctgtgggg gagacaacat tggaagtcaa agtgtgcact ggtaccagca
       61 caagccaccg caggcccctg tactggtcat cttttattat accgaacggc cctcaggaat
      121 ccctgagcga ttctctggct ccaaatcagg gaacaccgcc accctgacca tcagcggggt
      181 cgaggccggg gatgaggctg actattactg tcaggtgtgg gacacaacta ttgatcacgg
      241 cttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      301 cactctcttc ccg
//
LOCUS       KCWK01000150             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:9727:8784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000150
VERSION     KCWK01000150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:9727:8784"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65888.1"
                     /translation="DYYCSAWDSSLTGGLF"
     J_segment       407..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           99 a          155 c          122 g          106 t
ORIGIN      
        1 acatggggga gcttcagctg tggctagaga agacaggact caggacaatc tccagcatgg
       61 cctgcttccc tctcatcctc accgtcctca ctcactgtgc aggatcctgg gcccagtctg
      121 tgctgactca accaccctca gcgtctgggg cccccgggca gagtgtcacc atctcatgtt
      181 ctggaagcag ctccaacatc ggaagtaatt atgtatactg gtaccagcag ttctcaggga
      241 aggcccccaa actcctcatc cataataata atcagcgacc ctcaggggtc cctgatcgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagtccgaac
      361 atgaggctga ttattactgc tcagcatggg atagcagtct gaccggtggc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000151             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:18229:13918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000151
VERSION     KCWK01000151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18229:13918"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65889.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       412..448
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           96 a          158 c          124 g          108 t
ORIGIN      
        1 acatggggag cgcagcttca gctgtgggta cagaaggcag gactcaggac aatctccagc
       61 atggcctggt tccctctcgt cctcaccctc ctcactcact gtgcagggtc ctgggcccag
      121 tctgtgctga ctcagcctcc ctcagcgtct gaggccgcca ggaagagtgt caccatctcc
      181 tgttctggaa gcagctccaa catcggaagt aataatgtgt cctggtacca gcacctccca
      241 ggaacagctc ccaaactcct catctattat aatgatcaac gaggctcagg tgtctctgac
      301 cgattctctg gctccaagtc tggcacgtca gcctccctgg ccatcagtgg gctccagacc
      361 gaggatgagg ctgattatta ctgcgcagcg tgggatgata gcctgagcag ttacatcttc
      421 gctgctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      481 ttcccg
//
LOCUS       KCWK01000152             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:15944:7292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000152
VERSION     KCWK01000152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15944:7292"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..296
                     /note="immunoglobulin light chain variable region"
     V_region        8..296
     V_segment       8..259
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <215..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65890.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       260..296
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>334
                     /gene="IGLC"
BASE COUNT           71 a           98 c           99 g           66 t
ORIGIN      
        1 acatggggga cagacagcca gcatcacctg ctctggaaat aaattgggga atgtatatgc
       61 ttactggttc cagcagaagc caggccaggc ccctgtagtg gtcatctaca aagataccaa
      121 ccggccctca gggatccctg agcgattctc tggctccgac tcagggaaca cggccaccct
      181 gaccatcagc agggtcgagg ctggggatga ggccgactat ttttgtgctg cagcctatgg
      241 cagtggcagc agctggcagt gggtattcgg cggagggacc cggctaatcg tcctaggtca
      301 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000153             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:9019:17712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000153
VERSION     KCWK01000153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9019:17712"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65891.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       397..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           82 a          156 c          125 g          106 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcatctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagcattggc aacagctatg tgtactggtt ccagcagcgg ccgggcagcg tccccactat
      241 tgcgatttac aaagatgacc aaagaccctc tggggtccct gatcgattct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctgga ctgaagtctg gggacgaggc
      361 tgactattac tgtcagtctt ttgacagcag cagtgtctta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000154             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:16350:9607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000154
VERSION     KCWK01000154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16350:9607"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65892.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       373..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           95 a          141 c          113 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga agaattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtcca gatcatctat gaggacagta
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aagctgacta ctactgtttc tcaacagaca
      361 ccagtggtaa tcgggtattc ggcggaggga cccgtctaac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000155             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:19389:5832
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000155
VERSION     KCWK01000155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19389:5832"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65893.1"
                     /translation="DYYCQVWGMTSDHPVF"
     J_segment       397..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          141 c          137 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gattctgcgg cctccaatga tctgactcag
      121 ccacccccgg tgtcagcgtc cccaggacag acggccagga tcacctgtgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atttatgctg atagcgaacg gccctcaggg atccctgacc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac cattagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaagtgt ggggtatgac tagtgatcat ccggttttcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000156             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:5810:4614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000156
VERSION     KCWK01000156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5810:4614"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65894.1"
                     /translation="HYYCQVWDINTDHVLF"
     J_segment       388..424
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           89 a          141 c          131 g          101 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtgatg ttgtgaattg gtaccaccag aagccaccgc aggcccctgt actggtcatc
      241 tatgctaata gcgatcggcc ctcagggatc cctgagcgat tctctggctc catatcaggg
      301 aacacggcca ccctgaccat caacggggtc gaggccgggg atgaggctca ctattactgt
      361 caggtgtggg acattaatac tgatcatgtg ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000157             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:25436:16376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000157
VERSION     KCWK01000157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:25436:16376"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65895.1"
                     /translation="DYYCAAWDNSLTSPLL"
     J_segment       409..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           93 a          158 c          121 g          109 t
ORIGIN      
        1 acatggggag cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag ccaccctcag cgtctggggc tcccgggcag agtgtcacca tctcttgctc
      181 tggaagcagc tccaacattg gaactaatta tgtatactgg taccagcagc tcccaggaac
      241 ggcccccaaa gtcctcatct attatagtaa tcagcgaccc tcaggggtcc ctgaccgatt
      301 ctctgcctct aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga
      361 tgaggctgat tattactgtg cagcgtggga taacagccta actagtccgt tactcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01000158             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:9657:4064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000158
VERSION     KCWK01000158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9657:4064"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65896.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       393..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT          106 a          137 c          121 g          101 t
ORIGIN      
        1 acatggggct gtggttctag gaggaagagc tctgggtgtc tcaccatgac ctggaccact
       61 gttctgctcc cctttctcac tctctgcaca ggctctgagg cctcctatga gctgacacag
      121 ccaccctcag tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagaaata
      181 ctggcaaaaa aatatactca gtggttccag cagcagccag gccaggcccc tttcctggtg
      241 atatataaag acagtgagag gccctcaggg atccctgagc gattctctag ctccagttca
      301 gggacaacaa ttaccttgac catcagtggg gcccaggcag aagatgaggc tgactattac
      361 tgtcaatcag tagacagcag tggaaatctt ccgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000159             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:17275:12837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000159
VERSION     KCWK01000159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17275:12837"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65897.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       392..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT          101 a          136 c          123 g          104 t
ORIGIN      
        1 acatggggtg tggttctagg aggaagagct ctgggtgtct caccatgacc tggaccactg
       61 ttctgctccc ctttctcact ctctgcacag gctctggggc ctcctatgag gtgacacagt
      121 caccctcagt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagcaatac
      181 tggcaaataa ttatgctcag tggttccagc agaagccaga ccaggcccct gtgttggtga
      241 tatataaaga cactgagagg ccctcaggga tccctgagcg attctctagc tccagttcag
      301 ggacaacaat taccttgacc atcagtgggg cccaggcaga agatgaggct gactattact
      361 gtcaatcagt tgacagcagt gcccatcatc cgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000160             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:24204:15258
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000160
VERSION     KCWK01000160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:24204:15258"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..425
                     /note="immunoglobulin light chain variable region"
     V_region        102..425
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65898.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       390..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>464
                     /gene="IGLC"
BASE COUNT           91 a          146 c          130 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gttctggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg aatctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaagt cttgatcacg gcttatttgg aggagggacc cggctgaccg
      421 tcctaagtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000161             276 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:9747:17304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000161
VERSION     KCWK01000161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 276)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 276)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..276
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9747:17304"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..238
                     /note="immunoglobulin light chain variable region"
     V_region        9..238
     V_segment       9..202
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <166..>210
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65899.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       206..238
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        239..>276
                     /gene="IGLC"
BASE COUNT           55 a           82 c           83 g           56 t
ORIGIN      
        1 acatgggctg tgcactggta ccagcagaag ccaccgcagg gccctgtatt ggtcatcttt
       61 gctgatagta aacggccctc ggggatccct gagcgattct ctggctccaa ctcagggaac
      121 accgccaccc tgaccatcag cagggtcgag gccggggatg aggctgacta ttactgtcag
      181 gtgtgggaca gtagtagtaa atggatattc ggcgggggga cccggctaac cgtcctaggt
      241 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000162             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:8981:20344
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000162
VERSION     KCWK01000162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8981:20344"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65900.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           85 a          153 c          124 g          107 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacgatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccgggaagag tgtctccatc tcctgttctg gaagcagctc
      181 caacatcgga agtcatagtg tctcctggta ccagcagctc ccaggaacag ctcccaaact
      241 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctctca
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcatgggatg atagcctgag cggttacatc ttcggtgttg ggacccggct
      421 cgccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000163             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:14494:17661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000163
VERSION     KCWK01000163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14494:17661"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65901.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          154 c          128 g          112 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaacatt ggaggttatt atgtgcagtg gtaccagcag cttccaggag
      241 cggcccccaa actcctcatc tatgaaaatg ataaacgacc ctcaggggtt tctgatcgat
      301 tctctggctc ccagtctgat tcctcagcct ccctgaccat cactggactc cagtctgagg
      361 atgaggctga ttattactgc cagtcctatg acagcagctt gagtgttgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000164             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:3240:10578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000164
VERSION     KCWK01000164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:3240:10578"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65902.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           87 a          143 c          139 g           92 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgcggggga gacaagattg
      181 gaagtgaagt tgtgaactgg taccagcaga agccagcgca ggcccctgtg ctggtcatct
      241 atgctgatag cgaacggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acacggccac cctgaccatc agcggggtcg aggccggggg tgaggctgac tattactgtc
      361 aggtgtggga catgcgtagt gatcaaccgc tattcggcgg agggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000165             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:4693:19209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000165
VERSION     KCWK01000165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4693:19209"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65903.1"
                     /translation="DYYCAAWDDGLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          156 c          128 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcgggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatggcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000166             501 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:20776:14902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000166
VERSION     KCWK01000166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 501)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20776:14902"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..463
                     /note="immunoglobulin light chain variable region"
     V_region        115..463
     V_segment       115..424
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <391..>435
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65904.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       429..463
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        464..>501
                     /gene="IGLC"
BASE COUNT           98 a          163 c          122 g          118 t
ORIGIN      
        1 acatgggagt ggttcaacgc agagtacatg ggggcaggga aagaggctgt gtccaccatg
       61 gcctggactc ctctcctcct cctgctcctc tctcactgca caggttccct ctcccagcct
      121 gtgctgaccc agccaacctc cctctcagca tctccgggag catcagtcag actcagctgc
      181 accttgagca gtggcatcaa tgttggttct tacaccatat tctggtacca gcagaagcca
      241 gggagtcctc cccggttcct tctgtactac tactcagact caaataatca ccagggctct
      301 ggagtcccca gccgcttctc tggatccaaa gatgcttcag ccaatgcagg gcttttactg
      361 atctctgggc tccagtctga agatgaggct gactattact gtgccatgtg gcacagcagc
      421 gcttatgcct tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      481 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000167             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:22697:13877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000167
VERSION     KCWK01000167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:22697:13877"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..387
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65905.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       392..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT          105 a          136 c          122 g          101 t
ORIGIN      
        1 atgggggctg tggttctagg aggaagagct ctgggtgtct caccatgacc tggaccactg
       61 ttctgctccc ctttctcact ctctgcacag gctctgaggc ctcctatgag ctgacacagc
      121 caccctcagt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagaaatac
      181 tggcaaaaaa atatactcag tggttccagc agcagccagg ccaggcccct ttcctggtga
      241 tatataaaga cagtgagagg ccctcaggga tccctgagcg attctctagc tccagttcag
      301 ggacaacaat taccttgacc atcagtgggg cccaggcaga agatgaggct gactattact
      361 gtcaatcagt agacagcagt ggaaatcttc cgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000168             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:10763:3355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000168
VERSION     KCWK01000168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10763:3355"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..264
                     /note="immunoglobulin light chain variable region"
     V_region        6..264
     V_segment       6..227
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <189..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65906.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       228..264
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>302
                     /gene="IGLC"
BASE COUNT           65 a           91 c           84 g           62 t
ORIGIN      
        1 acatgggggg agacaacatt ggaagtaaga gtgtgcactg gtaccaacac aagccaccgc
       61 aggcccctat cctggtcatc tattattata ccgaacggcc ctcggcgatc cctgagcgat
      121 tctctggctc caaatcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg
      181 atgaggctga ctattactgt caggtgtggg acactactat tgatcatggc tttttcggag
      241 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      301 cg
//
LOCUS       KCWK01000169             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:7755:21223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000169
VERSION     KCWK01000169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7755:21223"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..423
                     /note="immunoglobulin light chain variable region"
     V_region        93..423
     V_segment       93..386
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65907.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       387..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           87 a          154 c          115 g          105 t
ORIGIN      
        1 acatggggga ggcaggactc aggacaatct ccagcatggc ctggttccct ctcgtcctca
       61 ccctcctcac tcactgtgca gggtcctggg cccagtctgt gctgactcag cctccctcag
      121 cgtctgaggc cgccaggaag agtgtctcca tctcctgttc tggaagcagc tccaacatcg
      181 gaagtcatag tgtctcctgg taccggcacc tcccaggaac agctcccaaa ctcctcatct
      241 attatagtga tcaacgagcc tcaggtgtct ctgaccgatt ctctggctcc aagtctggca
      301 cgtcagcctc cctggccatc agtgggctcc agaccgagga tgaggctgat tattactgcg
      361 cagcatggga tgataacctg agcggttaca tcttcggttc tgggacccga ctcaccgtcc
      421 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01000170             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:11100:13513
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000170
VERSION     KCWK01000170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11100:13513"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65908.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           85 a          157 c          128 g          110 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggtacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcagc ctccctcagc gtctgaggcc gccgggaaga gtgtctccat ctcctgttct
      181 ggaagcagct ccaacatcgg aagtcatagt gtctcctggt accagcagct cccaggaaca
      241 gctcccaaac tcctcgtcta ttatagtgat caacgagcct ctggtgtctc tgaccgattc
      301 tctggcgctc agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat
      361 gaggctgatt attactgcgc agcatgggat gatagcctga gcggttacat cttcggtgct
      421 gggacccggc tcgccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000171             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:7261:19037
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000171
VERSION     KCWK01000171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7261:19037"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65909.1"
                     /translation="DYYCQVWGSRSDHPVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          149 c          138 g           93 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag ggtcacctgt gggggaggca
      181 acattggaag taattatgtt cactggtacc agcagaagcc agcgcaggcc cctgttcagg
      241 tcatctatgc tgataacaaa cggccctcag ggatccctga acgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtggggcagt cgtagtgatc atccggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000172             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:15349:10155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000172
VERSION     KCWK01000172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15349:10155"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65910.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          158 c          118 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ttgcctacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gcgctggagt ccccagccgc ttctctggat
      301 ccaataatgc ttcagggaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccgtctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000173             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:13411:10584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000173
VERSION     KCWK01000173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13411:10584"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65911.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       408..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>457
                     /gene="IGLC"
BASE COUNT           95 a          145 c          112 g          105 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatatac tggtaccacc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacacat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tgattatatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagcccc aaggctt
//
LOCUS       KCWK01000174             271 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11792:11375
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000174
VERSION     KCWK01000174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 271)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 271)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..271
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11792:11375"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..233
                     /note="immunoglobulin light chain variable region"
     V_region        9..233
     V_segment       9..193
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <161..>205
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65912.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       196..233
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        234..>271
                     /gene="IGLC"
BASE COUNT           54 a           81 c           75 g           61 t
ORIGIN      
        1 acatggggca gggagtcctc cccggtatct tctgagatac aaatcggact cagataaggg
       61 ccagggctct ggagtcccca gccgcttctc tggatccaaa gatgcttcag cgaacgcagg
      121 gattttacgc atctctggac tccagtctga ggatgaggct gactattact gtgccattgg
      181 gcacagcagc ggtgattaca tcttcggtgc tgggacccgg ctcaccgtcc taggtcagcc
      241 caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01000175             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11147:11183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000175
VERSION     KCWK01000175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11147:11183"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65913.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       394..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          154 c          122 g          106 t
ORIGIN      
        1 acatgggggg tacagaaggc aggactcagg acaatctcca gcatggcctg gttccctctc
       61 gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc agtctgtgct gactcagcct
      121 ccctcagcgt ctgaggccgc cgggaagagt gtctccatct cctgttctgg aagcagctcc
      181 aacatcggaa gtcatagtgt ctcctggtac cagcagctcc caggaacagc tcccaaactc
      241 ctcatctatt atagtgatca acgagcctca ggtgtctctg accgattctc tggctctcag
      301 tctggcacgt cagcctccct ggccatcagt gggctccaga ccgaggatga ggctgattat
      361 tactgcgcag catgggatga tagcctgagc ggttacatct tcggtgctgg gacccggctc
      421 gccgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01000176             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:17343:16916
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000176
VERSION     KCWK01000176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17343:16916"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..388
                     /note="immunoglobulin light chain variable region"
     V_region        88..388
     V_segment       88..351
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <316..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65914.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       352..388
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           83 a          136 c          113 g           94 t
ORIGIN      
        1 acatgggggc agagctctgg gtgtctcacc atggcctgga ttcctctcct actccccatc
       61 ctcactttct gcacaggctc tgcagcctcc tatgagctga cacagccacc ctcggtgtca
      121 gtgtccccag gacagccggc caggatcacc tgctctggag atgtattgcc aaaaaaatat
      181 gcttattggt tccagcagaa gccaggccag tcccctgtat tggtcatctc tgaggacacc
      241 gaacggccct ctggctccag ctcagggaca gtggccacct tgactatcag tggggcccag
      301 gtggaggatg aagctgacta ctactgttac tcagcagaca gtagtggtca tggcttcttc
      361 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      421 ttcccg
//
LOCUS       KCWK01000177             497 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:23069:15679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000177
VERSION     KCWK01000177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 497)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 497)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..497
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:23069:15679"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    129..459
                     /note="immunoglobulin light chain variable region"
     V_region        129..459
     V_segment       129..422
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>431
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65915.1"
                     /translation="DYYCAAWDDSLTGYIF"
     J_segment       423..459
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        460..>497
                     /gene="IGLC"
BASE COUNT           95 a          158 c          128 g          116 t
ORIGIN      
        1 acatggggga tttgggtgaa gcgcagcttc agctgtgggt acagaaggca ggactcagga
       61 caatctccag catggcctgg ttccctctcc tcctcaccct cctcactcac tgtgcagggt
      121 cctgggccca gtctgtgctg actcagcctc cctcagcgtc tgaggccgcc aggaacagtg
      181 tcaccatctc ctgttctgga agcagctcca acatcggaag taatagtgtt tcctggtacc
      241 agcagctccc agaaacggct cccaaactcc tcatctatta taatgatcgg cgagcctcag
      301 gtgtctctga ccgattctct ggctccaagt ctggcacgtc agcctccctg gccatcagtg
      361 ggctccagac cgaggatgag gctgattatt actgcgctgc atgggatgat agcctgaccg
      421 gttacatatt cggttttggg acccggctca ccgtcctagg tcagcccaag gcttccccca
      481 cggtcactct gttcccg
//
LOCUS       KCWK01000178             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:10248:11438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000178
VERSION     KCWK01000178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10248:11438"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65916.1"
                     /translation="DYYCQSHDTSSVFF"
     J_segment       398..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          161 c          125 g          104 t
ORIGIN      
        1 acatgggggc tgtggctcag gaagcagagc ctggagcatc tccaccatgg cctgggctcc
       61 actcctcctc accctcctcg ctcactgcac agggtcttgg gctgaggttg tgttcactca
      121 gccccattct gtgtcggggt ctccggggca gacggtcacc atctcctgca cccgcagcag
      181 tggcagcatt gacaacagtt ttgtgtactg gtaccagcag cggccgggca gcgcccccac
      241 cactgtgatt tacgcagata accaaagacc ctctggggtc cctgatcggt tctctggctc
      301 catcgacagc tcctccaact ctgcctccct caccatctct ggactgaagt ctgaggacga
      361 ggctgactac tactgtcagt ctcatgacac cagcagtgtg tttttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000179             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:19102:20588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000179
VERSION     KCWK01000179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19102:20588"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65917.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          164 c          123 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagcctc
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagcaggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000180             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:13369:13479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000180
VERSION     KCWK01000180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:13369:13479"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65918.1"
                     /translation="DYYCQSGDSSGNHWVF"
     J_segment       392..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          103 a          131 c          132 g          100 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 ggcacccgca gtgtcagtgt ccccaggaca gacggccagg atcacctggt ctggagaaat
      181 actggcaata aaagatagtc agtggttcct gcagaagcca ggccaggccc ctctgatggc
      241 gatatatgaa gactctgaga ggccctcagg gattcctgag agattctcta gttccagttc
      301 agggccaaca gttacctcga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca ggagacagca gtggtaatca ttgggtattc ggcggaggga cccggctaag
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000181             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:15147:8142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000181
VERSION     KCWK01000181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15147:8142"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65919.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          158 c          118 g          112 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacgtacac tggtaccaac agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg ggtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tctttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000182             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15233:9731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000182
VERSION     KCWK01000182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15233:9731"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65920.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          161 c          117 g          108 t
ORIGIN      
        1 acatgggggc tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcgtcaatg
      181 tgggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacca gtcagactca aggaaacacc agggctctgg agtccccagc cacttctctg
      301 gatccaaaga tgcttcagcc aatgcaggac tattactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccctatggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000183             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:24109:13667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000183
VERSION     KCWK01000183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:24109:13667"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65921.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          152 c          115 g          116 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttggtaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaattacca cagagactca gatattcacc agggctctgg agtccccagc cgcttctctg
      301 ggtccaagga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggta ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000184             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14909:7541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000184
VERSION     KCWK01000184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14909:7541"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65922.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       392..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          140 c          141 g           98 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgc ggcctcctat gcggtgactc
      121 agccacgctc agtgtccgtg tccccaggac aggcggccag gatcacctgt gggggagaca
      181 atattggaag taaaagtgtc cagtggtacc agcagacgcc accgcaggcc cctgtactgg
      241 tcatttatgg tgatagggaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggatagt agtagtaaat atgtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000185             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:11834:7712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000185
VERSION     KCWK01000185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11834:7712"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..258
                     /note="immunoglobulin light chain variable region"
     V_region        7..258
     V_segment       7..222
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <186..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65923.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       223..258
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           61 a           92 c           74 g           69 t
ORIGIN      
        1 acatgggtga catcggtggt tataactatg tctcctggta ccaacagcat ccaggcacag
       61 cccccaaagt catgatttat gaggtcagta agcggccctc aggggtctct gatcgcttct
      121 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag gctgaggacg
      181 aggctgatta ttactgcagc tcatatacag gcatcaacag ttacatcttc ggtggtggga
      241 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000186             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:18333:11880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000186
VERSION     KCWK01000186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18333:11880"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65924.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       406..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           87 a          153 c          129 g          112 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct ctccttctca ctctgctggt tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag catctggggc ccccgggcag agggtcacca tctcctgcac
      181 tgggagcagc tccaacatcg gggcgggttt ttatgtttcc tggtaccagc agttcccagg
      241 aacagccccc aaactcctca tctttgaaaa taataagcga ccctcagggg tttctgaccg
      301 attctctggc tccaagtctg gttcctcagc ctccctgacc atcactggac tccaatctga
      361 ggatgaggct gattattatt gttcatcatg ggagagcagc ctgaattggg tattcggcgg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01000187             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:7985:19848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000187
VERSION     KCWK01000187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7985:19848"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65925.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          150 c          117 g          107 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac gcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000188             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:12834:19639
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000188
VERSION     KCWK01000188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12834:19639"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..439
                     /note="immunoglobulin light chain variable region"
     V_region        94..439
     V_segment       94..400
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65926.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       402..439
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           85 a          160 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac aggttccctc tcccagcctg tgctgactca gccaccctcc
      121 ctgtctgcat ccccgggagc atcggccaga ctcccctgca ccctgagcag tgacctcagt
      181 gttggtagta aaaacatgta ctggtaccag cagaagccag ggagcgctcc caggttattc
      241 ctgtactact actccgactc agacaagcag ctgggacctg gggtccccaa tcgagtctct
      301 ggctccaagg agacctcaag taacacagcg tttttgctca tctctgggct ccagcctgag
      361 gacgaggccg attatttctg ccaggtgttt gacagtagtg ttgtgttctt cggaggaggg
      421 acccgactga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000189             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:22348:17271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000189
VERSION     KCWK01000189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:22348:17271"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65927.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          153 c          121 g          112 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggtgtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000190             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:5243:17837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000190
VERSION     KCWK01000190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5243:17837"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65928.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          158 c          129 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacgg aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtc cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaggca gctccaacat cggcagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcgt ctattatgat gatcaacgag cctcaggtgt ctctggccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000191             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:10102:12116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000191
VERSION     KCWK01000191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10102:12116"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65929.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       403..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          152 c          123 g          112 t
ORIGIN      
        1 acatgggggc ttggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatggagg cagcaatagt ttgttcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000192             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:19797:14117
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000192
VERSION     KCWK01000192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19797:14117"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65930.1"
                     /translation="DYYCQVWDIYIDQPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          138 c          136 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcagcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000193             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:11409:5156
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000193
VERSION     KCWK01000193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11409:5156"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65931.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          157 c          117 g          111 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 gtgtctacca catacactgg taccaactga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gttctggagt ccccagccgc ttctctggat
      301 ccagtaatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000194             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:16256:10529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000194
VERSION     KCWK01000194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16256:10529"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65932.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          147 c          131 g           98 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctccgatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa gagtgtgcac tggtaccagc acaagccacc gcaggcccct atcctggtca
      241 tctattatta taccgaacgg ccctcggcga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacactact attgatcatg gctttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000195             394 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:10156:7238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000195
VERSION     KCWK01000195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 394)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10156:7238"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..356
                     /note="immunoglobulin light chain variable region"
     V_region        8..356
     V_segment       8..319
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>328
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65933.1"
                     /translation="DYYCAMWHSSASYFF"
     J_segment       320..356
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        357..>394
                     /gene="IGLC"
BASE COUNT           80 a          128 c           93 g           93 t
ORIGIN      
        1 acatgggcag cctgtgctga cccagccaac ctccctctca gcatctccgg gagcatcagc
       61 cagactcagc tgcaccttga acagtggcat caatgttggt agttacagca ttttctggta
      121 ccagcagaag ccagggagtc ctccccggta ccttctgtac tactactcag actcaagtaa
      181 acaccagggc tctggagtcc ccagccgctt ctctggatcc aaagatgctt cggccaatgc
      241 aggcctttta ctgatctctg ggctccagtc tgaagatgag gctgactatt actgtgccat
      301 gtggcacagc agcgcttctt acttcttcgg tactgggacc cggctcaccg tcctaggtca
      361 gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000196             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:14585:22675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000196
VERSION     KCWK01000196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14585:22675"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65934.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          142 c          132 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagctatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga attgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000197             318 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:5984:7674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000197
VERSION     KCWK01000197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 318)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:5984:7674"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..280
                     /note="immunoglobulin light chain variable region"
     V_region        8..280
     V_segment       8..240
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>252
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65935.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       244..280
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        281..>318
                     /gene="IGLC"
BASE COUNT           67 a           86 c           95 g           70 t
ORIGIN      
        1 acatggggga tcacctgtgg gggagacaat attggaagtg aagttgtcaa ctggtaccag
       61 cagaagccac cgcaggcccc tgtggtggtc atctatgctg attatgaacg gccctcaggg
      121 atccctgagc gattctctgg ctccaaatca gggaacacgg ccaccctgac catcagcgga
      181 gtcgaggccg gggatgaggc tgactattac tgtcaggttt gggacattta tattgatcat
      241 ccggtgttat tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc
      301 tcggtcactc tcttcccg
//
LOCUS       KCWK01000198             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:18589:10035
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000198
VERSION     KCWK01000198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18589:10035"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65936.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           88 a          141 c          117 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagccggcc aggatcacct gctctggaga tgtattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtatt ggtcatctct gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gtagtggtca tggcttcttc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000199             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:10594:3004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000199
VERSION     KCWK01000199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:10594:3004"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65937.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          149 c          116 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctacttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000200             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:23243:15367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000200
VERSION     KCWK01000200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:23243:15367"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65938.1"
                     /translation="DYYCSSWESSLNWIF"
     J_segment       407..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          154 c          129 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggttacc atctcctgca
      181 ctgggagcag ctccaacatc ggggcgggtt tttatgtgtc ctggtaccaa cagttccctg
      241 gaacagcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgctcatcat gggaaagcag cctgaattgg atattcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000201             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:8209:19230
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000201
VERSION     KCWK01000201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8209:19230"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..426
                     /note="immunoglobulin light chain variable region"
     V_region        103..426
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65939.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>465
                     /gene="IGLC"
BASE COUNT           92 a          147 c          128 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacagtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttatttg gaggagggac ccggctgacc
      421 gtcctaagtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000202             501 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:18234:7377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000202
VERSION     KCWK01000202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 501)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18234:7377"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    133..463
                     /note="immunoglobulin light chain variable region"
     V_region        133..463
     V_segment       133..427
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <391..>435
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65940.1"
                     /translation="DYYCCSYTTSSTWVF"
     J_segment       428..463
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        464..>501
                     /gene="IGLC"
BASE COUNT           96 a          161 c          128 g          116 t
ORIGIN      
        1 acatggggaa cacagggctg ggggcaggtc cagtgctggg gtctcagaag gcagcgctct
       61 caggacgtct ccaccatggc ctggactctg ctcctcgtca ccctcctcac tcaaggcaca
      121 ggatcctggg ctcagtctgc cccgactcag cctccctcta tgtctgggtc tcctggacag
      181 tcggtcacca tctcctgcac tggaaccacc agtgacattg gtggttataa ttatgtctcc
      241 tggtaccagc agcacccaga caaagccccc aaactcataa tttatggtgt cagaaatcgg
      301 ccctcagggg tctcttatcg cttctctggc tccaagtctg gtaatacggc ctccctgacc
      361 atctctgggc tccaggctga ggacgaggct gattattact gttgttcata tacaaccagt
      421 agcacttggg tattcggcgg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      481 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000203             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:18206:13845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000203
VERSION     KCWK01000203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18206:13845"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..391
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65941.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       394..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           87 a          150 c          123 g          106 t
ORIGIN      
        1 acatggggga cagaaggcag gactcaggat aatctccagc atggcctggt tccctctcgt
       61 actcaccctc ctcactcact gtgcagggtc ctgggcccag tctgtgctga ctcagccacc
      121 ctcagcgtct ggggctcccg ggcagagtgt caccatctct tgttctggaa gcatctccag
      181 cattggaagt agtgatgtat gttggtacca gcaactccca ggaacggccc ccaaactcct
      241 catcaattat agtgatcagc gactctcagg ggtccctgac cgattctctg gctctaagtc
      301 tggcacctca gcctccctgg ccatcactgg tctccgatct gaggatgagg ctgattatta
      361 ctgtgcagcc tgggatagca gcctgagcag tccggtattc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000204             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:24096:18223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000204
VERSION     KCWK01000204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:24096:18223"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65942.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          156 c          127 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacggg cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000205             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:7669:17125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000205
VERSION     KCWK01000205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7669:17125"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    41..389
                     /note="immunoglobulin light chain variable region"
     V_region        41..389
     V_segment       41..350
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <317..>361
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65943.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       352..389
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        390..>427
                     /gene="IGLC"
BASE COUNT           87 a          137 c           97 g          106 t
ORIGIN      
        1 acatgggctg ctcctctctc actgcacagg ttccctctcg cagcctgtgc tgactcagcc
       61 aacctccctc tcagcttctc ctggagcatc agccagactc acctgcacct tgaacagtgg
      121 catcagtgtt gctaattaca ggatattctg gtaccaccag aagccaggga gtcctccccg
      181 gtatcttctg aactaccaca cagactcaga tattcaccag ggctctggag tccccagccg
      241 cttctctgga tccaaagatg cttcggccaa tgcagggatt ttactcatct ctggactcca
      301 gtctgaggat gaggctgact attactgtat gatttggcac aacaatgctt attgggtttt
      361 cggcggaggg acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct
      421 cttcccg
//
LOCUS       KCWK01000206             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:18212:8146
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000206
VERSION     KCWK01000206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18212:8146"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65944.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          156 c          117 g          114 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaagctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtcttatg atgctgtgtc ttggtaccaa cagcctccag gcaaagcccc
      241 ccaactcata atttttgagg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgctgctcat atgtaggcag caacacttac atcttcgatg ttgggacccg
      421 gctcaccgtc ctaggtcagt ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01000207             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:9406:13915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000207
VERSION     KCWK01000207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9406:13915"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65945.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       396..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           87 a          150 c          124 g          107 t
ORIGIN      
        1 acatgggggg tacagaaggc aggactcagg ataatctcca gcatggcctg gttccctctc
       61 gtactcaccc tcctcactca ctgtgcaggg tcctgggccc agtctgtgct gactcagcca
      121 ccctcagcgt ctggggctcc cgggcagagt gtcaccatct cttgttctgg aagcatctcc
      181 agcattggaa gtagtgatgt atgttggtac cagcaactcc caggaacggc ccccaaactc
      241 ctcatcaatt atagtgatca gcgactctca ggggtccctg accgattctc tggctctaag
      301 tctggcacct cagcctccct ggccatcact ggtctccgat ctgaggatga ggctgattat
      361 tactgtgcag cctgggatag cagcctgagc agtccggtat tcggcggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000208             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:22513:10753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000208
VERSION     KCWK01000208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22513:10753"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..240
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65946.1"
                     /translation="DYYCQVWGSRSDHPVF"
     J_segment       243..277
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>315
                     /gene="IGLC"
BASE COUNT           62 a           92 c           96 g           65 t
ORIGIN      
        1 acatgggggg tcacctgtgg ggcaggtaac attggaagta attttgttca ctggtaccag
       61 cagaagccac cgcaggcccc tgttcaggtc atctatgcag ataacagacg gccctcaggg
      121 atccctgagc gattctctgg ctccaattca gggaacaccg ccaccctgac catcagcggg
      181 gtcgaggccg gggatgaggc tgactattac tgtcaggtgt ggggcagtcg tagtgatcat
      241 ccggtattcg gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      301 gtcactctct tcccg
//
LOCUS       KCWK01000209             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:19927:19661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000209
VERSION     KCWK01000209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19927:19661"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65947.1"
                     /translation="DYYCQVWDSSTRYAVF"
     J_segment       397..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          146 c          136 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcat tgccagcggc ctcaggacag acggccagga ttgcctgtgg gggagacagc
      181 attggaagtg aaaatgtgtt ctggtaccag cagaagccac ggcaggcccc tgtcctggtc
      241 atctatggtg atacgaaacg gccctcaggg atccctgagc gattctctgg ctccatctct
      301 gggaacaccg ccaccctgac catcaacagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tactagatac gcggttttcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000210             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:12807:5368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000210
VERSION     KCWK01000210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:12807:5368"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..398
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65948.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       402..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           86 a          157 c          125 g          105 t
ORIGIN      
        1 acatgggggg ctgtggctca ggaagcagag cctggagcat ctccaccatg gcctgggctc
       61 cactcctcct caccctcctc gctcactgca cagggtcttg ggctgaggtt gtgttcactc
      121 agccccattc tgtgtcgggg tctccggggc agacggtcac catctcctgc acccgcagca
      181 gtggcagcat tgacaacggc tttgtgtact ggtaccagca gcggccgggc agcgctccca
      241 ccactgtgat ttacaaagat aaccaaagac cctctggggt ccctgatcgg ttctctggct
      301 ccatcgacag ctcctccaac tctgcctccc tcaccatctc tggactgaaa tctgaggacg
      361 aggctgacta ttactgtcag tcttatgaca gcagcagtgt attattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000211             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:13768:10295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000211
VERSION     KCWK01000211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13768:10295"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65949.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          156 c          127 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca agtcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgaggggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000212             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:19648:17675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000212
VERSION     KCWK01000212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19648:17675"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65950.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          157 c          117 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagtcagg gagtcctccc cggtatcttc
      241 taaaatacaa atcagactca gatcagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgtttcagcg aacacgggga ttttacacgt ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattggcc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000213             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:6199:22050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000213
VERSION     KCWK01000213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6199:22050"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..303
                     /note="immunoglobulin light chain variable region"
     V_region        5..303
     V_segment       5..266
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <222..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65951.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       267..303
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           72 a          102 c          100 g           67 t
ORIGIN      
        1 acatggggtc cccaggacag acagccagca tcacctgctc tggaaataaa ttggggaatg
       61 tatatgctta ctggttccag cagaagccag gccaggcccc tgtagtggtc atctacaaag
      121 ataccaaccg gccctcaggg atccctgagc gattctctgg ctccgactca gggaacacgg
      181 ccaccctgac catcagcagg gtcgaggctg gggatgaggc cgactatttt tgtgctgcag
      241 cctatggcag tggcagcagc tggcagtggg tattcggcgg agggacccgg ctaatcgtcc
      301 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000214             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:18849:18879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000214
VERSION     KCWK01000214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18849:18879"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..389
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65952.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       396..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           88 a          157 c          114 g          112 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaagctgc cccgactcag
      121 cctccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgatattg ggtcttataa tgctgtgtcc tggtaccaac agcatccagg caaagccccc
      241 caactcataa tttttgaggt caataagcgg ccctcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccaggctga ggatgaggct
      361 gattattact gctgctcata tgtaggcagc aacacttaca tcttcgatat tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01000215             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:27033:12372
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000215
VERSION     KCWK01000215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:27033:12372"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65953.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          151 c          118 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaacagtgtc gccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattatg atgatcaacg agcctcaagt gtctctgacc gattctctgg ctccaggtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattat
      361 tgcgcagcat gggatgatag cctgagaggt tacatcttcg gtgatgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000216             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:24947:15759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000216
VERSION     KCWK01000216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:24947:15759"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    132..398
                     /note="immunoglobulin light chain variable region"
     V_region        132..398
     V_segment       132..361
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <329..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65954.1"
                     /translation="DYYCQTWDTGIVSF"
     J_segment       362..398
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>436
                     /gene="IGLC"
BASE COUNT           82 a          145 c          114 g           95 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctctgagca gtggacacag cagctacacc atcgcatggc atcagcacca
      181 gcaagggaag gcccctcggt atttgatgtg gcttaaaagt gatggcagcc acagcaaggg
      241 ggacgggatc cctgatcgct tctcaggctc cagttccggg gctgagcgct acctcaccat
      301 ctccaatttc cagtctgagg atgaggctga ttattactgt cagacctggg atactggcat
      361 tgtgtcattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      421 ggtcactctc ttcccg
//
LOCUS       KCWK01000217             401 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:20865:20080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000217
VERSION     KCWK01000217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 401)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20865:20080"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..363
                     /note="immunoglobulin light chain variable region"
     V_region        99..363
     V_segment       99..326
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <294..>335
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65955.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       327..363
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        364..>401
                     /gene="IGLC"
BASE COUNT           72 a          136 c           97 g           96 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt actactactc cgactcagac aaggagacct
      241 caactaacac agcgtttttg ctcatctctg ggctccagcc tgaggacgag gccgattatt
      301 actgtcaggt gtttgacagt agtgctgtgt tattcggagg agggacccga ctgaccgtcc
      361 taggtcagcc catggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000218             328 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:4870:4962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000218
VERSION     KCWK01000218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 328)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:4870:4962"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..290
                     /note="immunoglobulin light chain variable region"
     V_region        7..290
     V_segment       7..253
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <209..>262
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65956.1"
                     /translation="DYYCAAGYGSGSDWQWVF"
     J_segment       254..290
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        291..>328
                     /gene="IGLC"
BASE COUNT           70 a           99 c           95 g           64 t
ORIGIN      
        1 acatgggaca gccatcatca cctgctctgg aaatgaattg gggaatgtat atgcttcctg
       61 gtaccaccag aagccaggcc aggcccctgt attggtcatc tacaaagata ccaaccggcc
      121 ctcagggatc cctgagcgat tctctggctc caactcaggg aacacggcca ccctgaccat
      181 cagcagggtc gaggctgggg atgaagccga ctattactgt gctgcaggct atggcagtgg
      241 gagcgactgg cagtgggtat tcggcggggg gacccggcta accgtcctag gtcagcccaa
      301 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000219             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:12802:20512
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000219
VERSION     KCWK01000219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12802:20512"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65957.1"
                     /translation="DYYCATWNDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          156 c          123 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaagtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccggaccgag
      361 gatgagactg attattactg cgcaacatgg aatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000220             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:23031:15851
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000220
VERSION     KCWK01000220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23031:15851"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65958.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          153 c          120 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctctcagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccaggccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag tctgagcggt tacatcttcg gtgctgggac ccggctcgcc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000221             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:11861:6928
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000221
VERSION     KCWK01000221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:11861:6928"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65959.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          152 c          123 g          111 t
ORIGIN      
        1 acatgggggc ttggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatggagg cagcaatagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctagggc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000222             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:25329:10934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000222
VERSION     KCWK01000222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:25329:10934"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65960.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          155 c          120 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatgtt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacgcttta ttcttcggac gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc tccctcggtc actctcttcc cg
//
LOCUS       KCWK01000223             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:23236:11681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000223
VERSION     KCWK01000223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:23236:11681"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65961.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          144 c          141 g           93 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccag cgcaggcccc tgtgctggtc
      241 atctatgctg atagcgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg ggggtgaggc tgactattac
      361 tgtcaggtgt gggacatgcg tagtgatcaa ccgctattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000224             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:7279:6222
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000224
VERSION     KCWK01000224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7279:6222"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65962.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          146 c          131 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg atctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000225             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:12359:12275
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000225
VERSION     KCWK01000225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12359:12275"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65963.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          162 c          116 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctctgcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcactg
      181 ttgctgccta ccacatacac tggtaccaac agaagccagg gagtcctccc cggtatcttc
      241 tgaggttcaa atcagactca gataaggacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcctcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctactactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccgcct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000226             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:14608:8439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000226
VERSION     KCWK01000226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14608:8439"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..434
                     /note="immunoglobulin light chain variable region"
     V_region        105..434
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65964.1"
                     /translation="DYYCSSFAGRNNLFF"
     J_segment       405..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>473
                     /gene="IGLC"
BASE COUNT           87 a          155 c          119 g          112 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtaatct tgggtatttt aatgctgtgt cttggtacca acaacatcca ggcaaagccc
      241 ccaaactcat gatttacgac gtcactaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgcagttca tttgccggca ggaacaattt atttttcgga ggagggaccc
      421 ggctgaccgt cctaagtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000227             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:17619:5825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000227
VERSION     KCWK01000227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17619:5825"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65965.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          149 c          116 g          109 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gactcggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000228             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:18215:5233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000228
VERSION     KCWK01000228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18215:5233"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65966.1"
                     /translation="DYHCQVYDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          163 c          125 g          108 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actacttctc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgttct tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta tcactgtcag gtgtatgaca gtagtgctgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01000229             522 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:18932:19004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000229
VERSION     KCWK01000229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 522)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 522)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..522
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18932:19004"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65967.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>522
                     /gene="IGLC"
BASE COUNT          101 a          171 c          143 g          107 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctagatccc aggcctgagc aaggacctct gccctccctg tcagacactt gcctgcctca
      481 gcaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000230             345 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:22795:10265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000230
VERSION     KCWK01000230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 345)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22795:10265"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..307
                     /note="immunoglobulin light chain variable region"
     V_region        8..307
     V_segment       8..270
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <226..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65968.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       271..307
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>345
                     /gene="IGLC"
BASE COUNT           72 a          104 c          102 g           67 t
ORIGIN      
        1 acatgggcgg tgtccccagg acagacagcc agcatcacct gctctggaaa taaattgggg
       61 aatgtatatg cttactggtt ccagcagaag ccaggccagg cccccgtagt ggtcatctac
      121 aaagatacca accggccctc agggatccct gagcgattct ctggctccga ctcagggaac
      181 acggccaccc tgaccatcag cagggtcgag gctggggatg aggccgacta tttttgtgct
      241 gcagcctatg gcagtggcag cagctggcag tgggtattcg gcggagggac ccggctaatc
      301 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000231             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:9228:15311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000231
VERSION     KCWK01000231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9228:15311"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65969.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          152 c          115 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgttgac tcagcctccc
      121 tcagcgtctg aggccgccgg gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta atagtgtatc ctggtaccaa caactcccag aaacggctcc caaactcctc
      241 atgtattata atcatcggcg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacttcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagtgt gggatgatag cctgaccggt tacatcttcg gtactgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000232             496 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:24916:12172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000232
VERSION     KCWK01000232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 496)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:24916:12172"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..458
                     /note="immunoglobulin light chain variable region"
     V_region        110..458
     V_segment       110..420
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>430
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65970.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       424..458
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        459..>496
                     /gene="IGLC"
BASE COUNT           93 a          170 c          124 g          109 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcct ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      181 gagcactgac ctcagtgttg gtggtaaaaa catgtactgg taccagcaga agccaggaag
      241 cgctcccagg ttattgctgt attaccactc cgactcagac aagcagctgg gacctggggt
      301 ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc
      361 tgggctccag cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgccaa
      421 cacgttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      481 ggtcactctc ttcccg
//
LOCUS       KCWK01000233             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:21048:7109
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000233
VERSION     KCWK01000233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:21048:7109"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65971.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           89 a          141 c          116 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagccggcc aggatcacct gctctggaga tgtattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtatt ggtcatctct gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gtagtggtca tggcttcttc ggaggaggga cccggctgac cgtcctaggt cagcccaaga
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000234             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:22888:10598
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000234
VERSION     KCWK01000234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22888:10598"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..421
                     /note="immunoglobulin light chain variable region"
     V_region        103..421
     V_segment       103..389
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65972.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       390..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           93 a          138 c          128 g          100 t
ORIGIN      
        1 acatgggggg tgggctcaga agcagagctc tggggtgtct ccaccatggc ctggactcct
       61 ctctggctca ccctcctcag tctttgcaca ggttctgtgg tttcttctga gctgactcag
      121 gaccctgcag tgtctgtggc cttgggacag acagtcagga tcacctgcca aggagacagc
      181 ctcagaagtt attatgcaag ttggtaccag cagaagccag gccaggcccc tatactggtc
      241 gtctatggta acaattaccg gccctcaggg atcccagagc gattctctgg ctccagtaca
      301 cgaaacacag cttccttgac catcactggg gctcaggtgg aagatgaggc tgactattac
      361 tgtgactcct gggacagccg cggaacccaa ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000235             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:4869:11834
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000235
VERSION     KCWK01000235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:4869:11834"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65973.1"
                     /translation="AYFCQVWDSETDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          150 c          128 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gactctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaagccac cgcaggcccc tatgcaggtc
      241 atctatgctg ataacaaacg gccctcaggg atccctggga gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctatttc
      361 tgtcaggtgt gggacagtga aactgatcat tacatcttcg gtgctgggac ccggcttacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000236             294 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:19067:8279
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000236
VERSION     KCWK01000236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 294)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19067:8279"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    36..256
                     /note="immunoglobulin light chain variable region"
     V_region        36..256
     V_segment       36..219
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <181..>228
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65974.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       220..256
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        257..>294
                     /gene="IGLC"
BASE COUNT           62 a           94 c           78 g           60 t
ORIGIN      
        1 acatggggac agaaggcagg actcagaaag cagctccagc agctcccagg aacagctccc
       61 aaactcctca tctattatag tgatcaacga gcctcaggtg tctctgaccg attctctggc
      121 tccaagtctg gcacgtcagc ctccctggcc atcagcgggc tccaggccga ggatgaggct
      181 gattattact gcgcagcatg ggatgatagc ctgagcggtt acatcttcgg tgctgggacc
      241 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000237             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:6773:19746
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000237
VERSION     KCWK01000237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:6773:19746"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..285
                     /note="immunoglobulin light chain variable region"
     V_region        8..285
     V_segment       8..242
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <210..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65975.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       250..285
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>322
                     /gene="IGLC"
BASE COUNT           66 a           91 c          102 g           63 t
ORIGIN      
        1 acatggggac ggccagggtc acctgtgggg gagacaacat cggaggtgaa gttgtgaatt
       61 ggtaccagca gaagccaccg caggcccctg tgttggtcat ctatgctgat agcgagcggc
      121 cctcagggat cccggagcga ttctctggct ccaaatcagg gaacacggcc accctgacca
      181 tcagcggggt cgaggccgga gatgaggctg actattactg tcaggtgtgg gaccttaata
      241 gtcatcatct gttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg
      301 ccccctcggt cacctcttcc cg
//
LOCUS       KCWK01000238             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:23332:6494
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000238
VERSION     KCWK01000238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23332:6494"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..242
                     /note="immunoglobulin light chain variable region"
     V_region        8..242
     V_segment       8..204
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <170..>214
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65976.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       208..242
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        243..>280
                     /gene="IGLC"
BASE COUNT           60 a           85 c           76 g           59 t
ORIGIN      
        1 acatgggcag cagaagccag gaagcgctcc caggttattg ctgtattacc actccgactc
       61 agacaagcag ctgggacctg gggtccccaa tcgagtctct ggctccaagg agacctcaag
      121 taacacagcg tttttgctca tctctgggct ccagcctgag gacgaggccg attattactg
      181 tcaggtgtat gacagtagtg ccaacacgtt attcggagga gggacccggc tgaccgtcct
      241 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000239             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:19371:8935
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000239
VERSION     KCWK01000239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19371:8935"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..402
                     /note="immunoglobulin light chain variable region"
     V_region        78..402
     V_segment       78..364
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <327..>374
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65977.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       366..402
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        403..>440
                     /gene="IGLC"
BASE COUNT           85 a          142 c          120 g           93 t
ORIGIN      
        1 acatgggcgg tgcctcagcc atggcctgga cttttctcct cctcggcctc cttgcttact
       61 gcacaggctc tgcggcctcc tatgatctga ctcagccacc ctcggtgtca gtgtccccag
      121 gacagacggc caggatcacc tgtgggggag acaacattgg aagtcaaagt gtgcactggt
      181 accagcacaa gccaccgcag gcccctgttc tggtcatctt ttattatacc gaacggccct
      241 caggaatccc tgagcgaatc tctggctcca aatcagggaa caccgccacc ctgaccatca
      301 gcggggtcga ggccggggat gaggctgact attactgtca ggtgtgggac acaagtcttg
      361 atcacggctt attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      421 cctcggtcac tctcttcccg
//
LOCUS       KCWK01000240             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:11289:11969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000240
VERSION     KCWK01000240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:11289:11969"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65978.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       388..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           98 a          141 c          131 g           91 t
ORIGIN      
        1 acatggggtg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgag ctgactcagg
      121 caccctcagt gtcagcggcc tcaggacaga cggccaggat cacctgtggc ggagacaaca
      181 ttggaattaa aaatgtccac tggtaccagc agaagccagc acaggcccct gtggtagtca
      241 tctatgctga taacaaacgg ccctcaggga tccctgagcg actctctggc tccaactcag
      301 ggaatattgc caccctgacc atcagcaggg tcgaggccgg ggatgaggca gactattact
      361 gtcaggtgtg ggacagtagt agtaaatggg tattcggcgg agggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000241             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:26004:16831
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000241
VERSION     KCWK01000241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:26004:16831"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..394
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65979.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       399..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           89 a          149 c          124 g          109 t
ORIGIN      
        1 acatgggggt gggcacagga ggcagcactc aggacagtct ccagcatggc ctggtctcct
       61 ctcctcctca cccttctcat tcactgcaca gggtcctggg cccagtctgt gctgacgcag
      121 ccgccctcag tgtctggggc gcccgggcag agggtcacga tctcctgcag tgggagcaac
      181 tccaacattg gatattatta tgtgcagtgg taccagcagc ttccaggaac ggcccccaaa
      241 ctcctcatct atgaaaataa taagcgaccc tctggggttt ctgatcgatt ctctggctcc
      301 cagtctggta cctcagcctc cctgaccatc actggactcc agtctgagga tgaggctgat
      361 tattactgcc actcctatga cagcagtttg agtggtgtct tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000242             378 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:3893:15932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000242
VERSION     KCWK01000242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 378)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 378)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:3893:15932"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..340
                     /note="immunoglobulin light chain variable region"
     V_region        13..340
     V_segment       13..300
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>312
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65980.1"
                     /translation="DFYCQVWDIYVDHPVLF"
     J_segment       304..340
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        341..>378
                     /gene="IGLC"
BASE COUNT           76 a          111 c          111 g           80 t
ORIGIN      
        1 acatgggcgg cctcctatga tctgactcag ccaccctcgg tgtcagtgtc cccaggacag
       61 acggccagga tcacctgtgg aggagacaac attggaagtg aagttgtcaa ctggtaccag
      121 cagaggccac cgcaggcccc tgtgctggtc atctatgctg attatgaacg gccctcaggg
      181 atccctgagc gattctctgg ctccaaatca gggaacacgg ccaccctgac catcagcgga
      241 gtcgaggccg gggatgaggc tgacttttat tgtcaggtgt gggacattta tgttgaccat
      301 ccggtgttat tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc
      361 tcggtcactc tcttcccg
//
LOCUS       KCWK01000243             285 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:15203:20318
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000243
VERSION     KCWK01000243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 285)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15203:20318"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..247
                     /note="immunoglobulin light chain variable region"
     V_region        5..247
     V_segment       5..208
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <172..>219
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65981.1"
                     /translation="VYYCGAWDSSLSGYIF"
     J_segment       210..247
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        248..>285
                     /gene="IGLC"
BASE COUNT           56 a           87 c           75 g           67 t
ORIGIN      
        1 acatggggaa attctgtatc ctggtaccag caggtcccag gaacggcccc caaagtcctc
       61 atctatgaca ataataagcg cccctcgggg gtttctgacc gattctctgg ctccaagtct
      121 ggtacctcag cctccctggc catcactgga ctccaggctg gagatgaggc tgtttattac
      181 tgcggagcat gggatagcag tctgagtggt tacatcttcg gtgatgggac ccggctcacc
      241 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000244             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:19775:13290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000244
VERSION     KCWK01000244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19775:13290"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65982.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           89 a          156 c          120 g          108 t
ORIGIN      
        1 acatgggggg ggatctcacg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc cggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt attcttcggg ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000245             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:16589:6506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000245
VERSION     KCWK01000245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16589:6506"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65983.1"
                     /translation="AYYCQVWDSDSDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          149 c          128 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccatga tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaagccag cgcaggcccc tatgcaggtc
      241 atctatgctg ataacaaacg gccctcaggg atccctgaga gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctattac
      361 tgtcaggtgt gggacagtga tagtgatcat tacatcttcg gtactgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000246             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:11113:16366
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000246
VERSION     KCWK01000246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11113:16366"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65984.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          162 c          122 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000247             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:15131:19251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000247
VERSION     KCWK01000247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:15131:19251"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65985.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       399..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          158 c          122 g          105 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa cagcatccag gcacagcccc
      241 caaagtcatg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat atacaggcat caacagttac atcttcggtg gtgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctcttcc cg
//
LOCUS       KCWK01000248             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:22022:2599
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000248
VERSION     KCWK01000248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22022:2599"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65986.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          162 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagagagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000249             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:16927:16474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000249
VERSION     KCWK01000249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16927:16474"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65987.1"
                     /translation="DYYCAAWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          160 c          123 g          107 t
ORIGIN      
        1 acatgggggc agcctcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtatcct ggtaccaaca actcccagaa
      241 acggctccca aattcctcat gtatcatagt catcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacctcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgaccggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000250             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:13102:3917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000250
VERSION     KCWK01000250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13102:3917"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65988.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           88 a          147 c          129 g           97 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc cgatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtaagag tgtgcactgg taccagcaca agccaccgca ggcccctatc ctggtcatct
      241 attattatac cgaacggccc tcggcgatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cactactatt gatcatggct ttttcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000251             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:7354:11653
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000251
VERSION     KCWK01000251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7354:11653"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65989.1"
                     /translation="DYYCCSYRSGPTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           83 a          157 c          126 g          107 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcagcgct ctcgggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcagtct gccctgactc
      121 agcctccctc agtgtccaag tctcttggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat tggtggttat aatggcgtct cctggtacca acaacactca gggacagccc
      241 ccaaactcct gatttatgat gtgaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgctgctca tataggagtg gacccacttg ggttttcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000252             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:6008:12447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000252
VERSION     KCWK01000252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:6008:12447"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65990.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          159 c          117 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ttgcctacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gcgctggagt ccccagccgc ttctctggat
      301 ccaataatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccgtctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000253             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:19942:15262
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000253
VERSION     KCWK01000253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19942:15262"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..265
                     /note="immunoglobulin light chain variable region"
     V_region        1..265
     V_segment       1..228
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65991.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       230..265
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           64 a           81 c           96 g           62 t
ORIGIN      
        1 acatgggggg gagacaacat tggaagtgaa gttgtgaact ggtaccagca gaaggcaccg
       61 caggcccctg tgttggtcat gtatgctgat agcgagcggc cctcagggat ccctgagcga
      121 ttctctggct ccaaatcagg gaacacggcc accctgacca tcagcggggt cgaggccggg
      181 gatgaggctg actattattg tcaggtgtgg gacatgaata gtcatcatct gttattcgga
      241 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      301 ccg
//
LOCUS       KCWK01000254             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:13844:8160
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000254
VERSION     KCWK01000254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13844:8160"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65992.1"
                     /translation="DYYCAAWDDSLRGYLF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          157 c          126 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta cctcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000255             353 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:14329:6121
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000255
VERSION     KCWK01000255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 353)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14329:6121"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..315
                     /note="immunoglobulin light chain variable region"
     V_region        8..315
     V_segment       8..276
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>287
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65993.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       281..315
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        316..>353
                     /gene="IGLC"
BASE COUNT           73 a          106 c           89 g           85 t
ORIGIN      
        1 acatgggggg agcatcagtc agactcagct gcaccttgag cagtggcatc aatgttggtt
       61 cttacaccat attctggtac cagcagaagc cagggagtcc tccccggttc cttctgtact
      121 actactcaga ctcaaataat caccagggct ctggagtccc cagccgcttc tctggatcca
      181 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      241 ctgactatta ctgtgccatg tggcacagca gcgcttatgc cttattcgga ggagggaccc
      301 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000256             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:10877:16782
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000256
VERSION     KCWK01000256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10877:16782"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65994.1"
                     /translation="DYYCQVYDSRANTLF"
     J_segment       413..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>485
                     /gene="IGLC"
BASE COUNT           92 a          166 c          122 g          105 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tctatgacag tagagccaac acgttattcg
      421 gaggagggac ccggctgacc gtcccaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000257             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:18845:8461
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000257
VERSION     KCWK01000257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18845:8461"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65995.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          138 c          140 g           98 t
ORIGIN      
        1 acatgggggg gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 gcaccctcga tttcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atgtatgctg atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacatgaa tagtcatcat ctgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000258             321 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:10105:9731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000258
VERSION     KCWK01000258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 321)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:10105:9731"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..283
                     /note="immunoglobulin light chain variable region"
     V_region        8..283
     V_segment       8..246
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>255
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65996.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       249..283
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>321
                     /gene="IGLC"
BASE COUNT           67 a           89 c           98 g           67 t
ORIGIN      
        1 acatgggcgg ccaggatcac ctgtggggga gacaacattg gaagtaatag tgtgcattgg
       61 taccagcaga agccaccgcg ggcccctgta ttggtcatct ctgttgatag cgaacggccc
      121 tcagggatcc ctgagcgatt ctctggttcc agatcaggga acaccgccac cctgaccatc
      181 agcggggtcg aggccgggga tgaggctgac tattactgtc aggtgtggga taatatttat
      241 aaatacgcgg tattcggcgg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      301 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000259             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:8685:13511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000259
VERSION     KCWK01000259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8685:13511"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..433
                     /note="immunoglobulin light chain variable region"
     V_region        85..433
     V_segment       85..394
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65997.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       396..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           89 a          155 c          116 g          111 t
ORIGIN      
        1 acatggggaa aagaggctgt gtccaccatg gcctggactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctccaagcct atgctgactc agccggcctc cctctcagca
      121 tctcctggag catcagccag tctcacatgc accttcagcg gtggcatcaa tgttgctgtc
      181 taccacgtac actggtacca gcagaagcca gggagtcccc cccggtatct tctgaggtac
      241 aaatcagact cagataaggg ccagggctct ggggtcccca gccgcttctc tggatccagt
      301 aatggttcag tgaacacagg gattttacgc atttctgggc tccagtctga ggatgaggct
      361 gactattact gtgccattgg gcacagcagc ggtctttaca tcttcggtgc tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01000260             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:21429:20731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000260
VERSION     KCWK01000260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21429:20731"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65998.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          153 c          123 g          103 t
ORIGIN      
        1 acatgggggt acagaaggca ggactcagga caatctccag catggcctgg ttccctctcc
       61 tcctcaccct cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagcctc
      121 cctcagcgtc tgaggccgcc aggaagagtg tcaccatctc ctgttctgga agcagctcca
      181 acatcggaag taatagtgtt tcctggtacc agcagctccc agaaacggct cccaaactcc
      241 tcatctttta taatgatcgg cgagcctcag gtgtctctga ccgattctct ggctccaagt
      301 ctggcacgtc agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt
      361 actgcgcagc atgggatgat agcctgagcg gtccggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000261             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:20336:10696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000261
VERSION     KCWK01000261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20336:10696"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV65999.1"
                     /translation="DYYCHVYDSSSNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctcc gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtagtaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000262             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15400:9707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000262
VERSION     KCWK01000262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15400:9707"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66000.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          147 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggccccta tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000263             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:26358:12410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000263
VERSION     KCWK01000263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:26358:12410"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..392
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66001.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       397..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           89 a          149 c          123 g          108 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctcctct
       61 cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc tgacgcagcc
      121 gccctcagtg tctggggcgc ccgggcagag ggtcacgatc tcctgcagtg ggagcaactc
      181 caacattgga tattattatg tgcagtggta ccagcagctt ccaggaacgg cccccaaact
      241 cctcatctat gaaaataata agcgaccctc tggggtttct gatcgattct ctggctccca
      301 gtctggtacc tcagcctccc tgaccatcac tggactccag tctgaggatg aggctgatta
      361 ttactgccac tcctatgaca gcagtttgag tggtgtctta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000264             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:26689:8881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000264
VERSION     KCWK01000264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:26689:8881"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66002.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       215..251
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           59 a           88 c           77 g           65 t
ORIGIN      
        1 acatggggga aggaatagtg tatcctggta ccagcagctc ccaggaacag ctcccaaact
       61 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctccaa
      121 gtctggcatg tcagcctccc tggccatcag cgggctccag accgaggatg agggtgatta
      181 ttactgcgca gcatgggatg atagcctgag cggttacatc ttcggtgctg ggacccggct
      241 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000265             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:27517:17509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000265
VERSION     KCWK01000265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:27517:17509"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66003.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          142 c          136 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag cctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000266             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:19952:15497
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000266
VERSION     KCWK01000266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19952:15497"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66004.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           91 a          142 c          133 g           94 t
ORIGIN      
        1 atggggctgg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacaga ctctgcgacc tcctatgaat tgactcagtc
      121 gccctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacgacat
      181 tggaactaaa actgtgcact ggtaccaaca gaagccaccg cagggccctc tattggtcat
      241 ctttgctgat agtagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taagcgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000267             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:19462:20301
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000267
VERSION     KCWK01000267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:19462:20301"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..266
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <233..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66005.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       268..305
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           66 a          106 c           92 g           79 t
ORIGIN      
        1 acatgggggg gcccccgggc agagggttac catctcctgc actgggagca gctccaacat
       61 cggggcgggt ttttatgtgt cctggtacca gcagttccct ggaacagccc ccaaactcct
      121 catctttgaa aataataagc gaccctcagg ggtttctgac cgattctctg gctccaagtc
      181 tggttcctca gcctccctga ccatcactgg actccagtct gaggatgagg ctgattatta
      241 ctgctcatca tgggaaagca gcctgaattg ggtattcggc ggagggaccc ggctgaccgt
      301 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000268             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:21353:7708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000268
VERSION     KCWK01000268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21353:7708"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66006.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          159 c          126 g          111 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01000269             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:13225:2261
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000269
VERSION     KCWK01000269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:13225:2261"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66007.1"
                     /translation="DYYCTSYAGSNTFVLF"
     J_segment       404..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           85 a          161 c          127 g          105 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagccgcgc tcactgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggcggtt ataactatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaactc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctgacgaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcactt catatgcagg cagcaacact ttcgtgttgt tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000270             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:6259:3911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000270
VERSION     KCWK01000270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6259:3911"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66008.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          165 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagctttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagccc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000271             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:14104:3816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000271
VERSION     KCWK01000271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14104:3816"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66009.1"
                     /translation="DYYCSSYAGINTFIF"
     J_segment       404..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          161 c          123 g          106 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtgatt ataactatgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaattc atgatttatg aggtcagtca gcggccctca ggggtctctg atcgcgtctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccggg ctgaggacga
      361 ggctgactat tactgcagct catatgcagg catcaacact ttcatcttcg gtggtgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000272             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:14525:18151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000272
VERSION     KCWK01000272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14525:18151"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..407
                     /note="immunoglobulin light chain variable region"
     V_region        87..407
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66010.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       372..407
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>446
                     /gene="IGLC"
BASE COUNT           92 a          141 c          116 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aagatcacct gctctggaga tgcactgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcgat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gcagtggtta tggcttattc ggaggaggga cccggctgac cgtcctacgt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000273             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:22180:10231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000273
VERSION     KCWK01000273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22180:10231"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..440
                     /note="immunoglobulin light chain variable region"
     V_region        110..440
     V_segment       110..405
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66011.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       407..440
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           89 a          153 c          121 g          115 t
ORIGIN      
        1 acatggggag tgctgggatc tcaggaggca gcgctctcag gacttctcca ccatggtctg
       61 ggctctgctc ctcctcaccc tcctcactca gggcacagga tcctgggttc aggctgcccc
      121 gactcagcct ccctctgtgt ccgggtctcc tggacagtcg gtcaccatct cctgcactgg
      181 aaccagcagt gatattggat attataacgc tgtgtcttgg taccaacagc atccaggcaa
      241 agcccccaaa ctcataattt ttgacgtcat taagcggccc tcagggctct ctgatcgctt
      301 ctctggctcc aagtctggcg acacggcctc cctgaccatc tctgggctcc gggctgagga
      361 tgaggctgat tattactgca gctcatatgc aggcagaaat aattttttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000274             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:25152:5758
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000274
VERSION     KCWK01000274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25152:5758"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..448
                     /note="immunoglobulin light chain variable region"
     V_region        115..448
     V_segment       115..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66012.1"
                     /translation="DYYCQSYDSNLSAMLF"
     J_segment       413..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          154 c          127 g          115 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac catctcctgc
      181 actgggagta gttccaactt cggggcgggt tattatgtgc actggtacca gcaacttcca
      241 ggaacggccc ccaaactcct catctatgaa aacaatatgc gaccctcagg ggtttctgat
      301 cgattctctg gctccaagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagta atttgagtgc tatgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01000275             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:16547:7403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000275
VERSION     KCWK01000275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16547:7403"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66013.1"
                     /translation="DYFCQVWDMNSHHLLF"
     J_segment       391..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          140 c          139 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagg
      121 caccctcgat ctcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtgaac tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tgtatgctga tagcgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactatttct
      361 gtcaggtgtg ggacatgaac agtcatcatc tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000276             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:4995:20283
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000276
VERSION     KCWK01000276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:4995:20283"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66014.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           95 a          154 c          112 g          116 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcg cagcctgtgc tgactcagcc aacctccctc
      121 tcagcttctc ctggagcatc agccagactc acctgcacct tgaacagtgg catcagtgtt
      181 gctaattaca ggatattctg gtaccaccag aagccaggga gtcctccccg gtatcttctg
      241 aactaccaca cagactcaga tattcaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcggccaa tgcagggatt ttactcatct ctggactcca gtctgaggat
      361 gaggctgact attactgtat gatttggcac aacaatgctt attgggtttt cggcggaggg
      421 acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000277             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:15095:12386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000277
VERSION     KCWK01000277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15095:12386"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66015.1"
                     /translation="DYYCSSYGGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          154 c          121 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatggagg cagcaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000278             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:6817:3313
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000278
VERSION     KCWK01000278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:6817:3313"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66016.1"
                     /translation="EYYCCSYTTSSTYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          155 c          118 g          115 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggatc
      181 cagcagtgac attggtaatt ctaactctgt ctcctggtac cagaagcacc caggcaaagc
      241 ccccaaagtc atgatttatg gtgtcagtaa tcgggcctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaacg cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgaatat tattgttgtt catatacaac cagtagtact tacattttcg gtgctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000279             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:22575:16527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000279
VERSION     KCWK01000279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22575:16527"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66017.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          141 c          136 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcctatgatc tgactcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccagggtc acctgtgggg gagacaacat
      181 cggaggtgaa gttgtgaatt ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat agcgagcggc cctcagggat cccggagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccgga gatgaggctg actattactg
      361 tcaggtgtgg gaccttaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000280             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18812:9243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000280
VERSION     KCWK01000280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18812:9243"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..436
                     /note="immunoglobulin light chain variable region"
     V_region        91..436
     V_segment       91..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66018.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           92 a          160 c          112 g          110 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgacccagcc aacctccctc
      121 tcagcatctc cgggagcatc agccagactc agctgcacct tgagcagtgg caatgttggt
      181 agttacagca tattctggta ccagcagaag ccagggagtc ctccccggta ccttctttac
      241 tactactcag actcaagtaa ccaccaggac tctggagtcc ccagccgctt ctctggatcg
      301 aaagatgctt cagccaatgc agggctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccac atggcacagc agcgcttctt acatcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000281             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:9145:18660
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000281
VERSION     KCWK01000281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9145:18660"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66019.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           92 a          145 c          132 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctcttcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg acagtaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000282             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:18858:19350
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000282
VERSION     KCWK01000282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18858:19350"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..396
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66020.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           92 a          159 c          116 g          107 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctct
      121 gcatctcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 gcctaccaca tacactggta ccagcagaag ccagggagtc ctccccggta tcttctgaga
      241 tataaatcag actcagataa ggaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgcct cagcgaacac gggacttttg cacatctctg ggctccagtc tgaggatgag
      361 gctgactact actgtgccat tgggcacagc agcggtgatt acatcttcgg tgctgggacc
      421 cgcctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000283             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:3107:12941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000283
VERSION     KCWK01000283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:3107:12941"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..431
                     /note="immunoglobulin light chain variable region"
     V_region        104..431
     V_segment       104..395
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66021.1"
                     /translation="LYYCCSYTTSSTYIF"
     J_segment       396..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           87 a          158 c          113 g          111 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cactgacgtt ggtggttata actctgtctc ctggtaccaa caggacccag gcaaagcccc
      241 caaactcatc atttatggtg tcagtaatcg gccaggggtc tctgatcgct tctctggctc
      301 caagtctggc aacacggcct ccctgaccat ctctgggctc caggctgagg acgaggctct
      361 ttattactgt tgttcatata caaccagtag cacttacatc ttcggtactg ggacccggct
      421 aaccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000284             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:11595:8066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000284
VERSION     KCWK01000284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11595:8066"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66022.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           97 a          152 c          125 g          107 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag actccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcaga tccaacatcg gaagaaatag tgtatcctgg taccagaagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agcgggctcc aggccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agcggttaca ttttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01000285             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:18151:13477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000285
VERSION     KCWK01000285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18151:13477"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66023.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          162 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tgttaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 cattcctata ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000286             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10403:9032
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000286
VERSION     KCWK01000286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10403:9032"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66024.1"
                     /translation="DYYCAMWHSSVYGLF"
     J_segment       404..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          155 c          114 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cgattccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tacttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagtagtgt ttatggctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000287             377 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:17504:8072
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000287
VERSION     KCWK01000287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 377)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17504:8072"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..339
                     /note="immunoglobulin light chain variable region"
     V_region        12..339
     V_segment       12..299
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <261..>311
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66025.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       303..339
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        340..>377
                     /gene="IGLC"
BASE COUNT           78 a          109 c          111 g           79 t
ORIGIN      
        1 acatgggggc ctcctatgat ctgactcagc caccctcggt gtcagtgtcc ccaggacaga
       61 cggccaggat cacctgtgga ggagacaaca ttggaagtga agttgtcaac tggtaccagc
      121 agaggccacc gcaggcccct gtggtggtca tctatgctga ttatgaacgg ccctcaggga
      181 tccctgagcg attctctggc tccaaatcag ggaacacggc caccctgacc atcagcggag
      241 tcgaggccgg ggatgaggct gactattatt gtcaggtgtg ggacatttat attgaccatc
      301 cggtgttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct
      361 cggtcactct cttcccg
//
LOCUS       KCWK01000288             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:19196:12071
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000288
VERSION     KCWK01000288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19196:12071"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66026.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          157 c          126 g          109 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtctcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcggcatggg atgatagcct gagcggttac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01000289             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:9620:18412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000289
VERSION     KCWK01000289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9620:18412"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66027.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          160 c          113 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg tgtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000290             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:15028:22390
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000290
VERSION     KCWK01000290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15028:22390"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66028.1"
                     /translation="DYYCAMWHSSAYVLF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          159 c          113 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgtctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000291             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:11834:8105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000291
VERSION     KCWK01000291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11834:8105"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66029.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           88 a          140 c          118 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagccggcc aggatcacct gctctggaga tgtattgcaa aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtatt ggtcatctct gaggacaccg
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gtagtggtca tggcttcttc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000292             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:10068:15777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000292
VERSION     KCWK01000292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10068:15777"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66030.1"
                     /translation="AYYCQVWDSDTDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          151 c          129 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccaggg tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaagccag cgcaggcccc tatgcaggtc
      241 atctatgctg ataccaaacg gccctcaggg atccctgaga gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctattac
      361 tgtcaggtgt gggacagtga tactgatcat tacatcttcg gtactgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000293             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:9823:9955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000293
VERSION     KCWK01000293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9823:9955"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..407
                     /note="immunoglobulin light chain variable region"
     V_region        87..407
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66031.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       372..407
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>446
                     /gene="IGLC"
BASE COUNT           92 a          140 c          117 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aagatcacct gctctggaga tgcactgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcgat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aaggtgacta ctactgttac tcagcagaca
      361 gcagtggtta tggcttattc ggaggaggga cccggctgac cgtcctacgt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000294             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:20342:17801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000294
VERSION     KCWK01000294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20342:17801"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..417
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66032.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       418..454
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           93 a          158 c          124 g          117 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact tcacagttcc agggtcctgg
      121 gcccagtctg tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc
      181 atctcctgca ctgggagcag ctccaacatt ggagattatt ttgtgcagtg gtaccagcac
      241 cttccaggaa cggcccccaa actcctcatt tatgaaaata ataagcgacc ctcaggcatt
      301 tctgatcgat tctctggctc ccagtctgga acctcagcct ccctgaccat cactggactc
      361 cagtctgagg atgaggctga ttattactgc cagtcctatg acagcagttt gattgctgtg
      421 ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCWK01000295             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:27353:10936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000295
VERSION     KCWK01000295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:27353:10936"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66033.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       398..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          156 c          115 g          115 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaagct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggatcca
      181 tcagtgatat tgggtcttat aatgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 cccaactcat aatttttgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tgacaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgctgctca tatgtaggca gcaacactta catcttcgat gttgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000296             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:25788:12714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000296
VERSION     KCWK01000296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:25788:12714"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..230
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <197..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66034.1"
                     /translation="DYYCSSWESSLNWVL"
     J_segment       232..269
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           61 a           94 c           79 g           73 t
ORIGIN      
        1 acatgggggg agcagctcca acatcggggc gggtttttat gtgtcctggt accagcaatt
       61 ccctggaaca gcccccaaac tcctcatctt tgaaaataat aagcgaccct caggggtttc
      121 tgaccgattc tctggctcca agtctggttc ctcagcctcc ctgaccatca ctggactcca
      181 gtctgaggat gaggctgatt attactgctc atcttgggaa agcagcctga attgggtact
      241 cggcggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01000297             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:19024:5340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000297
VERSION     KCWK01000297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19024:5340"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..376
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66035.1"
                     /translation="AYYCQVWDSDTDHYIF"
     J_segment       388..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          153 c          129 g           93 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctatgagc tgactcagcc
      121 cccctcggtg tcagcggcct caggccagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaat tttgtgcact ggtaccagca gaagccagcg caggccccta tgcaggtcat
      241 ctatgctgat gccaaacggc cctcagggat ccctgagaga ttctctggct ccaactccgg
      301 gaacaccgcc accctgacca tcagcggagt cgaggccgga gatgaggctg cctattactg
      361 tcaggtgtgg gacagtgata ctgatcatta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000298             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:14170:18031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000298
VERSION     KCWK01000298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14170:18031"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66036.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           86 a          158 c          129 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcgt ctattatagt gatcaacgag cctctggtgt ctctgaccga
      301 ttctctggcg ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000299             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:21698:18122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000299
VERSION     KCWK01000299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21698:18122"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66037.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          157 c          122 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacgtt cactctgttc
      481 ccg
//
LOCUS       KCWK01000300             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:14672:8878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000300
VERSION     KCWK01000300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14672:8878"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66038.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          147 c          130 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgtgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000301             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:24810:11035
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000301
VERSION     KCWK01000301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24810:11035"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..274
                     /note="immunoglobulin light chain variable region"
     V_region        8..274
     V_segment       8..237
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>246
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66039.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       238..274
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        275..>312
                     /gene="IGLC"
BASE COUNT           64 a           97 c           73 g           78 t
ORIGIN      
        1 acatgggtca atgttggtag ttacagcata ttctggtacc agcagaagcc agggagtcct
       61 ccccggtacc ttctctacta ctactcagac tcaagtaaac accagggctc tggagtcccc
      121 agccgcttct ctggatccaa agatgcttcg gccaatgcag gccttttact gatctctggg
      181 ctccagtctg aagatgaggc tgactattac tgtgccatat ggcacagcag cgcttcttac
      241 ttcttcggta ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      301 actctgttcc cg
//
LOCUS       KCWK01000302             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:17798:4692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000302
VERSION     KCWK01000302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17798:4692"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66040.1"
                     /translation="DYHCQVYDGSAVLF"
     J_segment       409..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           86 a          160 c          122 g          112 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag tagtgacctc
      181 agtgttggta gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgtact acttctccga ctcagacaag cagttgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatca ctgtcaggtg tatgacggta gtgctgtttt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000303             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:13255:14671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000303
VERSION     KCWK01000303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13255:14671"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66041.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          157 c          121 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat gttgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacgct ttattcttcg gacgagggac
      421 ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000304             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:12093:5059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000304
VERSION     KCWK01000304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12093:5059"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66042.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          155 c          126 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgattc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcgggtgt ctctgaccga
      301 ttctctggct ccaggtctga cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000305             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:3849:17646
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000305
VERSION     KCWK01000305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:3849:17646"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66043.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       403..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           91 a          159 c          112 g          113 t
ORIGIN      
        1 acatggggca gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccca gcctgtgctg acccagccaa cctccctctc
      121 agcatctccg ggagcatcag tcagactcag ctgcaccttg agcagtggca tcaatgttgg
      181 ttcttacacc atattctggt accagcagaa gccagggagt cctccccggt tccttctgta
      241 ctactactca gactcaaata atcaccaggg ctctggagtc cccagccgct tctctggatc
      301 caaagatgct tcagccaatg cagggctttt actgatctct gggctccagt ctgaagatga
      361 ggctgactat tactgtgcca tgtggcacag cagcgcttat gccttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000306             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12488:6506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000306
VERSION     KCWK01000306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12488:6506"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66044.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>484
                     /gene="IGLC"
BASE COUNT           90 a          162 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tccg
//
LOCUS       KCWK01000307             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:22272:3994
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000307
VERSION     KCWK01000307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:22272:3994"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..398
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66045.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           88 a          153 c          120 g          110 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 actccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgatattg ggtattatta tgctgtgtct tggtaccagc atcatccagg caaagccccc
      241 aagctcatga tttatgaggt caataaacgg cccgcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 gattattact gcagctcata tgcaggcagc aacactttat tcttcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000308             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:18524:8630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000308
VERSION     KCWK01000308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18524:8630"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..409
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66046.1"
                     /translation="VYYCGAWDSSLSGYIF"
     J_segment       411..448
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           94 a          157 c          125 g          110 t
ORIGIN      
        1 acatggggag ctctgcctca gctgtgagca cagaaggcag gacttgggac aatcttcatc
       61 atgacctggt cccctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct acggccccag ggcagaaggt caccatctcc
      181 tgctctggaa gtagctccaa catcgggaga aattctgtat cctggtacca gcaggtccca
      241 ggaacggccc ccaaagtcct catctatgac aataataagc gcccctcggg ggtttctgac
      301 cgattctctg gctccaagtc tggtacctca gcctccctgg ccatcactgg actccaggct
      361 ggagatgagg ctgtttatta ctgcggagca tgggatagca gtctgagtgg ttacatcttc
      421 ggtgatggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      481 ttcccg
//
LOCUS       KCWK01000309             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:7735:4936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000309
VERSION     KCWK01000309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:7735:4936"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66047.1"
                     /translation="DYYCQVWDSTSDHVFF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          141 c          137 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 gccctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacgacat
      181 tggaagtaaa tatgtgcact ggtaccagca gaagccaccg caggcccctg tgctggtcat
      241 ctattatgat ggcgaacggc cctcagggat ccctgagcga ttctctgact ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtacta gtgatcatgt gtttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000310             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:15456:15918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000310
VERSION     KCWK01000310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15456:15918"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..400
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66048.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       403..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          160 c          119 g          107 t
ORIGIN      
        1 acatggggca gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccca gcctgtgctg acccagccaa cctccctctc
      121 agcatctccg ggagcatcag ccagactcag ctgcaccttg agcagtggcg tcaatgtggg
      181 tagttacagc gtattctggt accagcagaa gccagggagt cctccccggt accttctgta
      241 ctaccagtca gactcaagga aacaccaggg ctctggagtc cccagccgct tctctggatc
      301 caaagatgct tcagccaatg cagggctgtt actgatctct gggctccagt ctgaagatga
      361 ggctgactat tactgtgccc tatggcacag cagcgcttct tgcatcttcg gtggtgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000311             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:9240:17981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000311
VERSION     KCWK01000311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9240:17981"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66049.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       413..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           91 a          155 c          129 g          113 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag gttattatgt gcagtggtac cagcagcttc
      241 caggaacggc ccccaaactc ctcatctatg aaaatgataa acgaccctca ggggtttctg
      301 atcgattctc tggctcccag tctgattcct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagcttgagt gttgtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01000312             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:4981:11479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000312
VERSION     KCWK01000312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:4981:11479"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66050.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag tcgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccaac tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000313             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:3753:14980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000313
VERSION     KCWK01000313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:3753:14980"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66051.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          161 c          120 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg attcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gtgctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttgttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000314             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:16063:19038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000314
VERSION     KCWK01000314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16063:19038"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66052.1"
                     /translation="DYYCAAWDDRLTGYVF"
     J_segment       413..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          157 c          124 g          109 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcctcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg ggagcaatag tgtatcctgg taccagctgc tcccagaaac
      241 ggctcccaaa ctcctcatct attataataa tcggcgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatcgcctg accggttacg tattcggtgt
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01000315             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:16509:11444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000315
VERSION     KCWK01000315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16509:11444"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..264
                     /note="immunoglobulin light chain variable region"
     V_region        7..264
     V_segment       7..227
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66053.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       228..264
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>302
                     /gene="IGLC"
BASE COUNT           62 a           94 c           78 g           68 t
ORIGIN      
        1 acatgggcag ctccaacatc ggaagtcata gtgtatcctg gtaccagcag ctcccaggaa
       61 cagctcccaa actcctcatc tattatgatg atcaacgagc ctcgggtgtc tctgaccgat
      121 tctctggctc caggtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      181 atgaggctga ttattactgc gcagcatggg atgatagcct gagaggttac atcttcggtg
      241 atgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      301 cg
//
LOCUS       KCWK01000316             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:12193:13751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000316
VERSION     KCWK01000316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12193:13751"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66054.1"
                     /translation="DYYCQVWDIYTDHPVIF"
     J_segment       398..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          143 c          135 g          101 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gcctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tactgatcat ccggtgatat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000317             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:11727:13407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000317
VERSION     KCWK01000317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11727:13407"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66055.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          154 c          128 g          114 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctatgaaa atgataaacg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct gattcctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagtag cttgagtgtt gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000318             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:8120:9014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000318
VERSION     KCWK01000318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:8120:9014"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..226
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66056.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       227..263
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           64 a           91 c           87 g           59 t
ORIGIN      
        1 acatgggggg cacagcagct acaccatcgc atggcatcag cagcagcaag ggaaggcccc
       61 ccggtacttg atgtggctta aaagtgaagg cagccatagc aagggggacg ggatccctga
      121 tcgcttctca ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc
      181 tgaggatgag gctgattatt actgtcagac ctgggatact gacattgtgt tattcggagg
      241 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01000319             373 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:12180:15270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000319
VERSION     KCWK01000319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 373)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12180:15270"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..335
                     /note="immunoglobulin light chain variable region"
     V_region        14..335
     V_segment       14..299
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <263..>307
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66057.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       303..335
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        336..>373
                     /gene="IGLC"
BASE COUNT           82 a          108 c          108 g           75 t
ORIGIN      
        1 acatggggcg acctcctatg aattgactca gtcattctca gtgtcagcgg cctcaggaca
       61 gccggccagg atcacctgtg ggggagacaa cattggaact aaaactgtgc actggtacca
      121 acagaagcca ccgcagggcc ctgtattggt catctttgct gatagtagac ggccctcagg
      181 gatccctgag cgattctctg gctccaactc agggaacacc gccaccctga ccatcagcag
      241 ggtcgaggcc ggggatgagg ctgactatta ctgtcaggtg tgggacagta gtagtaaatg
      301 gatattcggc ggggggaccc ggctaaccgt cctaggtcag cccaaggctg ccccctcggt
      361 cactctcttc ccg
//
LOCUS       KCWK01000320             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:20314:8730
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000320
VERSION     KCWK01000320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20314:8730"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66058.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          161 c          123 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gttcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000321             498 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:12186:7638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000321
VERSION     KCWK01000321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 498)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12186:7638"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..460
                     /note="immunoglobulin light chain variable region"
     V_region        112..460
     V_segment       112..420
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <388..>432
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66059.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       423..460
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        461..>498
                     /gene="IGLC"
BASE COUNT          104 a          156 c          119 g          119 t
ORIGIN      
        1 acatggggac cgcagcccga ttgtgactct tctggcaaag atccctgaaa aatttgaccc
       61 tggtttctgc cttagcaccc aataatgtct gtgtttgcag gttccctctc caagcctatg
      121 ctgactcagc cggcctccct ctcagcatct cctggagcat cagccagtct cacatgcacc
      181 ttcagcggtg gcatcaatgt tgctggctac cacatacact ggtaccagca gaagccaggg
      241 agtcctcccc ggtatcttct gagatacaaa tcggactcag ataagggcca ggcctctgga
      301 gtccccagcc gcttctctgg atccaaagat gcttcagcga acacagggat tttacgcatc
      361 tctgggctcc agtctgagga tgaggctgac tattactgtg ccattggaca cagcagcggt
      421 gattacatct tcggtgctgg gtcccgactc accgtcctag gtcagcccaa ggcttccccc
      481 acggtcactc tgttcccg
//
LOCUS       KCWK01000322             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:4765:5555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000322
VERSION     KCWK01000322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:4765:5555"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66060.1"
                     /translation="DYYCAVWDDRLTGYVF"
     J_segment       415..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          158 c          124 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagcaat agtgtttcct ggtaccaaca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ccctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagtatgg gatgatcgcc tgaccggtta cgtattcggt
      421 gttgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000323             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:8899:8310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000323
VERSION     KCWK01000323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8899:8310"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    27..357
                     /note="immunoglobulin light chain variable region"
     V_region        27..357
     V_segment       27..313
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <285..>329
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66061.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       327..357
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        358..>395
                     /gene="IGLC"
BASE COUNT           80 a          123 c          102 g           90 t
ORIGIN      
        1 acatgggggg cacaggatcc tgggctcagg ctgccccgac tcagactccc tctgtgtccg
       61 ggtctcctgg acagtcggtc accatctact gcactggaac cagcagtgat attgggtatt
      121 atcatgctgt gtcttggtac caacatcatc caggcaaagc ccccaaactc atgatttatg
      181 aggtcaataa acggcccgca ggggtctctg atcgcttctc tggctccaag tctggcaaca
      241 cggcctccct gaccatctct gggctccaga ctgaggatga ggctgactat tactgcagct
      301 catatgcagg cagcaacagt ttattcttcg gaggagggac ccggctgacc gtcctaggtc
      361 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000324             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:17598:12478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000324
VERSION     KCWK01000324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17598:12478"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66062.1"
                     /translation="DYYCSIGHSSGLYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          157 c          117 g          115 t
ORIGIN      
        1 acatggggtc tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtttcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgagggtga ctattactgt tccattggac acagcagcgg tctttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000325             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:28626:12308
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000325
VERSION     KCWK01000325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:28626:12308"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66063.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          100 a          136 c          124 g          103 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagg tgacacagtc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagcaatact
      181 ggcaaataat tatgctcagt ggttccagca gaagccagac caggcccctg tgttggtgat
      241 atataaagac actgagaggc cctcagggat ccctgggcga ttctctagct ccagttcagg
      301 gacaacagtt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagtt gacagcagtg cccatcatcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000326             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12996:13578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000326
VERSION     KCWK01000326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12996:13578"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66064.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          153 c          113 g          117 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttggtaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcacc agggctctgg agtccccagc cgcttctctg
      301 ggtccaagga tgcttcggcc aatgcaggta ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattattgt atgatttggc acaacaatgc ttattgggta ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000327             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:8947:6417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000327
VERSION     KCWK01000327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8947:6417"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66065.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          164 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagcctc
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000328             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:26160:16972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000328
VERSION     KCWK01000328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:26160:16972"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..396
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66066.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           92 a          161 c          114 g          107 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctct
      121 gcatctcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 gcctaccaca tacactggta ccagcagaag ccagggagtc ctccccggta tcttctgaga
      241 tataaatcag actcagataa cgaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgcct cagcgaacac gggacttttg cgcatctctg ggctccagtc tgaggatgag
      361 gctgactact actgtgccat tggacacagc agcggtgatt acatcttcgg tgctgggacc
      421 cgcctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000329             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:25028:12474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000329
VERSION     KCWK01000329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:25028:12474"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66067.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           94 a          155 c          124 g          108 t
ORIGIN      
        1 atgggggcag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaataa tgtgtcctgg taccagcacc tcccaggaac
      241 agctcccaaa ctcctcatct attataatga tcaacgaggc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcgtggga tgataggctg agcagttaca tcttcgctgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01000330             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:26516:13415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000330
VERSION     KCWK01000330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:26516:13415"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66068.1"
                     /translation="DYSCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          148 c          129 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattcctg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000331             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:19756:9819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000331
VERSION     KCWK01000331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19756:9819"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..348
                     /note="immunoglobulin light chain variable region"
     V_region        28..348
     V_segment       28..312
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <277..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66069.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       313..348
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        349..>387
                     /gene="IGLC"
BASE COUNT           84 a          118 c          105 g           80 t
ORIGIN      
        1 acatgggtct gcacaggctc tgcagcctcc tatgagctga cacagccacc ctcggtgtca
       61 gtgtccccag gacagacggc caagatcacc tgctctggag atgcactgcc aaaaaaatat
      121 gcttattggt tccagcagaa gccaggccag tcccctgtgt tgatcatcga tgaggacacc
      181 aaacggccct ctgggatccc tgagagattc tctggctcca gctcagggac agtggccacc
      241 ttgactatca gtggggccca ggtggaggat gaagctgact actactgtta ctcagcagac
      301 agcagtggtt atggcttatt cggaggaggg acccggctga ccgtcctacg tcagcccaag
      361 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000332             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12276:17515
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000332
VERSION     KCWK01000332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12276:17515"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..404
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66070.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          156 c          123 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagtagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000333             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:14214:4502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000333
VERSION     KCWK01000333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14214:4502"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66071.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           91 a          142 c          131 g          104 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gtctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtgctggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcatcgga atcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000334             266 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:19730:17181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000334
VERSION     KCWK01000334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 266)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 266)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..266
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19730:17181"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..228
                     /note="immunoglobulin light chain variable region"
     V_region        6..228
     V_segment       6..189
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <156..>200
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66072.1"
                     /translation="DYYCMLWHNNAYWVF"
     J_segment       191..228
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        229..>266
                     /gene="IGLC"
BASE COUNT           50 a           80 c           68 g           68 t
ORIGIN      
        1 atggggggag tcctccccgg tatcttctga actaccacac agactcagat tttcaccagg
       61 gctctggagt ccccagccgc ttctctggat ccaaggatgc ttcggccaat gcagggattt
      121 tactcatctc tggactccag tctgaggatg aggctgacta ttactgtatg ctttggcaca
      181 acaatgctta ttgggttttc ggcggaggga cccggctaac cgtcctaggt cagcccaagg
      241 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000335             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:3382:11214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000335
VERSION     KCWK01000335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:3382:11214"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..444
                     /note="immunoglobulin light chain variable region"
     V_region        96..444
     V_segment       96..407
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66073.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       410..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          164 c          120 g          108 t
ORIGIN      
        1 acatggggcc cactgcaggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcccagcc tgtgctgacc cagccaacct
      121 ccctctcagc atctccggga gcatcagcca gactcagctg caccttgagc agtggcgtca
      181 atgtgggtag ttacagcgta ttctggtacc agcagaagcc agggagtcct ccccggtacc
      241 ttctgtacta ccagtcagac tcaaggaaac accagggctc tggagtcccc agccgcttct
      301 ctggatccaa agatgcttca gccaatgcag ggctgttact gatctctggg ctccagtctg
      361 aagatgaggc tgactattac tgtgccctat ggcacagcag cgcttcttgc atcttcggtg
      421 gtgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01000336             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:25406:20094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000336
VERSION     KCWK01000336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:25406:20094"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66074.1"
                     /translation="AYYCQVWDSETDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          150 c          128 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gactctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta tttttgtgca ctggtaccag cagaagccac cgcaggcccc tatgcaggtc
      241 atctatgctg atagcaaacg gccctcaggg atccctgaga gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctattac
      361 tgtcaggtgt gggacagtga aactgatcat tacatcttcg gtgctgggac ccggcttacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000337             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:18808:13954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000337
VERSION     KCWK01000337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18808:13954"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66075.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          162 c          119 g          111 t
ORIGIN      
        1 acatggggtg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcaatattg gcaataaaaa catgtactgg taccagcaga agccagggag cgctcccaag
      241 ttattcctgt actactactc cgactcagac atgcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtcat acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctgt attattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01000338             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:20988:14972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000338
VERSION     KCWK01000338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20988:14972"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66076.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          152 c          120 g          107 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttctggaag cagttccaac
      181 atcggaagtc atagtgtctc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctctcagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccaggccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag tctgagcggt tacatcttcg gtgctgggac ccggctcgcc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000339             517 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:22715:9689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000339
VERSION     KCWK01000339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 517)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22715:9689"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    149..479
                     /note="immunoglobulin light chain variable region"
     V_region        149..479
     V_segment       149..442
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <404..>451
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66077.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       443..479
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        480..>517
                     /gene="IGLC"
BASE COUNT          104 a          157 c          143 g          113 t
ORIGIN      
        1 acatggggag agtatgaaga gagggagaga tttgggtgaa gcgcagcttc agctgtgggt
       61 acagaaggca ggactcagga caatctccag catggcctgg ttccctctcg tcctcaccct
      121 cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagcctc cctcagcgtc
      181 tgaggccgcc aggaacagtg tcgccatctc ctgttctgga agcagcgcca acatcggaag
      241 tcatagtgta tcctggtacc agcagctccc aggaacagct cccaaactcc tcatctatta
      301 tgatgatcaa cgagcctcgg gtgtctctga ccgattctct ggctccaggt ctggcacgtc
      361 agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt actgcgcagc
      421 atgggatgat agcctgagag gttacatctt cggtgatggg acccggctca ccgtcctagg
      481 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01000340             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:5082:9381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000340
VERSION     KCWK01000340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:5082:9381"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66078.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          164 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctcccc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcgagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000341             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:10059:9564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000341
VERSION     KCWK01000341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10059:9564"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66079.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          160 c          114 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat actgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctaacta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tccttacatc ttcggtcctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000342             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14966:9076
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000342
VERSION     KCWK01000342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14966:9076"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66080.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          161 c          120 g          107 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagatacag atcagactca gataagggcc agggctctgg agtcccccgc cgcttctctg
      301 gatccaaaga tgctgcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctactactgt gccattgggc acagcagcgg tccttacttc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000343             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:13038:3942
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000343
VERSION     KCWK01000343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13038:3942"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66081.1"
                     /translation="DYYCQVWDSDSKWVF"
     J_segment       390..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          146 c          137 g           91 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc agtgtcagcg gcctcaggac agacggccag gatcacctgt ggcggggaca
      181 gccttggaac taaaaatgtg cactggtacc agcagaagcc agcgcaggcc cctgtggtgg
      241 tcatctatgc tgataataaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt gatagtaagt gggtcttcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000344             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:26685:14895
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000344
VERSION     KCWK01000344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:26685:14895"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..386
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66082.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       387..418
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>456
                     /gene="IGLC"
BASE COUNT           90 a          138 c          130 g           98 t
ORIGIN      
        1 acatgggggg gctcagaagc agagctctgg ggtgtctcca ccatggcctg gactcctctc
       61 tggctcaccc tcctcagtct ttgcacaggt tctatggttt cttctgagca gactcaggac
      121 cctgcagtgt ctgtggcctt ggggcagaca gtcaggatta cctgccaagg agacagcctc
      181 agaagctctt atgcaagctg gtaccaacag aggccaggcc aggcccctgt ggtggtcgtc
      241 tatggtaaca agtaccggcc ctcagggatc ccagagcgat tctctggctc ctactcccga
      301 aatacagctt ccttgaccat cactggggct caggtggaag atgaggctga ctattactgt
      361 gactcctggg acagcagggg aacccaattc ggaggaggga cccggctgac cgtcctaggt
      421 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000345             371 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:10870:12777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000345
VERSION     KCWK01000345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 371)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:10870:12777"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..333
                     /note="immunoglobulin light chain variable region"
     V_region        8..333
     V_segment       8..296
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <258..>305
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66083.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       297..333
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        334..>371
                     /gene="IGLC"
BASE COUNT           71 a          119 c           97 g           84 t
ORIGIN      
        1 acatgggtgt gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca
       61 tctcctgttc gggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcaac
      121 tcccaggaac agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct
      181 ctgaccgatt ctctggctcc cagtctggca cgtcagcctc cctggccatc agtgggctcc
      241 agaccgagga tgaggctgat tattactgcg cggcatggga tgatagcctg agcggttaca
      301 tcttcggtgg tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      361 ctctgttccc g
//
LOCUS       KCWK01000346             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:7941:5060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000346
VERSION     KCWK01000346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:7941:5060"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..397
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66084.1"
                     /translation="DYYCSSYAGSNILFF"
     J_segment       402..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           90 a          151 c          117 g          112 t
ORIGIN      
        1 acatggggga tctcaggagg cagcgctctc aggacttctc caccatggtc tgggctctgc
       61 tcctcctcac cctcctcact cagggcacag gatcctgggc tcaggctgcc ccgactcaga
      121 ctccctctgt gtccgggtct cctggacagt cggtcaccat ctcctgcact ggaaccagca
      181 gtgatattgg gtattatcat gctgtgtctt ggtaccaaca tcatccaggc aaagccccca
      241 aactcatgat ttatgaggtc aataaacggc ccgcaggggt ctctgatcgc ttctctggct
      301 ccaagtctgg caacacggcc tccctgacca tctctgggct ccagactgag gatgaggctg
      361 attattactg cagctcatat gcaggcagta atattttatt cttcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000347             348 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:11479:14779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000347
VERSION     KCWK01000347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 348)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11479:14779"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..310
                     /note="immunoglobulin light chain variable region"
     V_region        6..310
     V_segment       6..273
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <241..>282
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66085.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       274..310
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        311..>348
                     /gene="IGLC"
BASE COUNT           75 a          103 c           93 g           77 t
ORIGIN      
        1 atggggggag catcggccag actcccctgc accctgagca gtgacctcag tgttggtaat
       61 aaaaacatgt actggtacca acagaagcca gggagcgctc ccaggttatt cctgtactac
      121 tactccgact cagacaagca gctgggacct ggggtcccca atcgagtctc tggctccaag
      181 gagacctcaa ctaacacagc gtttttgctc atctctgggc tccagcctga ggacgaggcc
      241 gattattact gtcaggtgtt tgacagtagt gctgtgttat tcggaggagg gacccgactg
      301 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000348             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:9687:13887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000348
VERSION     KCWK01000348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:9687:13887"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66086.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           94 a          143 c          133 g           94 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gaactgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaat taaaactgta cactggtacc agcagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgatagtaag cggcccacag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000349             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:26267:10637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000349
VERSION     KCWK01000349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:26267:10637"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..398
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66087.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       399..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           90 a          154 c          123 g          106 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcggcact ctcgggacat ctccaccatg gcctgggatc
       61 tgctcctctt caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctccctc aatgtctggg tctcctggac agtcggtcac catctcctac actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagacc
      241 ccaaattcat gatttatgag gtcagtcaac ggccctcagg ggtctctgat cgtatctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctggttatta ctgcagctca tttgcaggta ccaacactgg cttaatcggt ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000350             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:12940:10152
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000350
VERSION     KCWK01000350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12940:10152"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66088.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       388..424
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT          108 a          135 c          121 g           98 t
ORIGIN      
        1 acatggggtg gttctaggag gaagagctct gggtgtctca ccatgacctg gaccactgtt
       61 ctgctcccct ttctcactct ctgcacaggc tctgaggcct cctatgacct gacacagcca
      121 ccctcagtgt cagtgtcccc agggcagacg gccaggatca cctgctctgg agaaatactg
      181 gcaaaaaaat atactcagtg gttccagcag aagtcaggcc agggccctag actggtgata
      241 tataaagaca gtgagaggcc ctcagggatc cctgagcgat tctctagctc cagttcaggg
      301 acaacagtca ccttgaccat cagcggggcc cagacagaag atgaggctga ctattactgt
      361 caatcagcag acagaagtcc taatcatgtg tttttcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000351             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16445:9929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000351
VERSION     KCWK01000351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16445:9929"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66089.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          155 c          121 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000352             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:20441:6261
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000352
VERSION     KCWK01000352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20441:6261"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..427
                     /note="immunoglobulin light chain variable region"
     V_region        81..427
     V_segment       81..390
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66090.1"
                     /translation="DYYCSIGHSSGLYIF"
     J_segment       392..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>467
                     /gene="IGLC"
BASE COUNT           86 a          158 c          111 g          112 t
ORIGIN      
        1 acatggggga ggctgtgtcc accatggcct ggactcctct cctcctcctg ctcctctctc
       61 actgcacagg ttccctctcc aagcctatgc tgactcagcc ggcctccctc tcagcatctc
      121 ctggagcatc agccagtctc acatgcacct tcaccggtgg catcaatgtt gctgtctacc
      181 acatacactg gtaccagcag aagccaggga gtcccccccg gtttcttctg aggtacaaat
      241 cagactcaga taagggccag ggctctggag tccccagccg cttctctgga tccagtaatg
      301 cttcagcgaa cacagggatt ttacgcattt ctgggctcca gtctgaggat gaggctgact
      361 attactgttc cattggacac agcagcggtc tttacatctt cggtgctggg acccggctca
      421 ccgtcctggg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01000353             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:20511:3488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000353
VERSION     KCWK01000353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20511:3488"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66091.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       409..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           89 a          154 c          128 g          110 t
ORIGIN      
        1 acatggggag cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtactca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag ccaccctcag cgtctggggc tcccgggcag agtgtcacca tctcttgttc
      181 tggaagcatc tccagcattg gaagtagtga tgtatgttgg taccagcaac tcccaggaac
      241 ggcccccaaa ctcctcatca attatagtga tcagcgactc tcaggggtcc ctgaccgatt
      301 ctctggctct aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga
      361 tgaggctgat tattactgtg cagcctggga tagcagcctg agcagtccgg tattcggcgg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01000354             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:21129:3400
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000354
VERSION     KCWK01000354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:21129:3400"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..421
                     /note="immunoglobulin light chain variable region"
     V_region        97..421
     V_segment       97..380
                     /gene="IGLV3-35"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <346..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66092.1"
                     /translation="DYYCGSWDNSDKRYIF"
     J_segment       384..421
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           92 a          139 c          122 g          106 t
ORIGIN      
        1 acatgggggt cagaagcaga actctgggtc gtctccacca tggcctggac ccctcccctg
       61 ctcatcctcc tcactctctg cacaggttcc gtggtttcct ctgggctgac tcaggagcct
      121 gcattgtctg tggccttggg acatacagtc aggatgacct gccaaggaga cagcctcaaa
      181 acctattacg caagctggta tcagcagaag ccaggccagg tccctgtgct ggtcatctat
      241 ggtaacacca ataggccctc agggatccca ggccgattct ctggctcctg gtcaggaaac
      301 tcaggttcct tgaccatcac tggggctcag gtggaagatg aggctgacta ttactgtggc
      361 tcctgggata acagtgataa gcgttacatc ttcggtgatg ggacccggtt caccgtccta
      421 ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000355             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:20850:20566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000355
VERSION     KCWK01000355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20850:20566"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..387
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66093.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       392..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT          105 a          136 c          122 g          101 t
ORIGIN      
        1 atgggggctg tggttctagg aggaagagct ctgggtgtct caccatgacc tggaccactg
       61 ttctgctccc ctttctcact ctctgcacag gctctgaggc ctcctatgag ctgacacagc
      121 caccctcagt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagaaatac
      181 tggcaaaaaa atatactcag tggttccagc agcagccagg ccaggcccct ttcctggtga
      241 tatataaaga cagtgagagg ccctcaggga tccctgagcg attctctagc tccagttcag
      301 ggacaacaat taccttgacc atcagtgggg cccaggcaga agatgaggct gactattact
      361 gtcaatcagt agacagcagt ggaaatcttc cgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000356             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:10050:14503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000356
VERSION     KCWK01000356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10050:14503"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66094.1"
                     /translation="DYYCSSYGGRNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          153 c          120 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atggaggcag aaacacttta ttcttcgcag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000357             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:21750:7211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000357
VERSION     KCWK01000357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21750:7211"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66095.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       391..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          142 c          136 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccagggtc acctgtgggg gagacaacat
      181 cggaggtgaa gttgtgaatt ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacgcggcc accctgacca tcagcggggt cgaggccgga gatgaggctg actattactg
      361 tcaggtgtgg gaccttaata gtcatcatct cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000358             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:20983:15945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000358
VERSION     KCWK01000358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20983:15945"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66096.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       392..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>464
                     /gene="IGLC"
BASE COUNT           90 a          144 c          134 g           96 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag actctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtgaac tggtaccagc agaagccacc gcaggcccct gtcctggtca
      241 tctatgctaa taacgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg gggcgttact agtgatcatc ccttattcgg aggagggacc cggctgaccg
      421 tccaaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000359             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:9150:6464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000359
VERSION     KCWK01000359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9150:6464"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66097.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          163 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccaac tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000360             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:16210:9403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000360
VERSION     KCWK01000360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16210:9403"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66098.1"
                     /translation="DYYCQSYDRSLNAVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          149 c          125 g          114 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac catttcctgc
      181 accgggagca gctccaacat tggagattat tatgtgcagt ggtaccagca ggttccagga
      241 acggccccca tactcctcat ctatgaaaat aataagcgac cctcaggggc ttccaatcga
      301 ttctctggct cccagtctgg tacctcagcc tcgctgacca taagtggact ccagtctgaa
      361 gatgaggctg actattattg tcagtcttat gacagaagtt taaatgctgt tttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01000361             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15398:18908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000361
VERSION     KCWK01000361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15398:18908"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66099.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       390..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>462
                     /gene="IGLC"
BASE COUNT           89 a          144 c          134 g           95 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacagac tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaggtgaag ttgtgaactg gtaccagcag aagccaccgc aggcccctgt cctggtcatc
      241 tatgctaata acgaacggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacacggcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg gcgttactag tgatcatccc ttattcggag gagggacccg gctgaccgtc
      421 caaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000362             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:8816:13014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000362
VERSION     KCWK01000362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:8816:13014"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66100.1"
                     /translation="DYYCQVWDSDSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           95 a          142 c          132 g           91 t
ORIGIN      
        1 atggggctgg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg tactgcgacc tcctatgaac tgactcagcc
      121 accctcagtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa aatgtgcact ggtaccagca gaagccagcg cagggccctg tattggtcat
      241 gtttgctgat accagacggc cctcagggat ccctgaccga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtgata gtaaatggat attcggcgga gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000363             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:15697:10623
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000363
VERSION     KCWK01000363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15697:10623"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66101.1"
                     /translation="DYSCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           81 a          157 c          127 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattct tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000364             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:23828:22748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000364
VERSION     KCWK01000364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23828:22748"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66102.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           96 a          157 c          123 g          106 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gactccctca gcgtctgagg ccgccagaaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagaaata gtgtatcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagcgggctc caggccgacg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagcggttac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01000365             295 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:9255:19307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000365
VERSION     KCWK01000365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 295)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9255:19307"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..257
                     /note="immunoglobulin light chain variable region"
     V_region        8..257
     V_segment       8..218
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <185..>229
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66103.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       220..257
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>295
                     /gene="IGLC"
BASE COUNT           63 a           85 c           77 g           70 t
ORIGIN      
        1 acatgggagg atattctggt accagcagag gccagggagt cctccccggt atcttctgaa
       61 ccaccacaca gactcagata aacatcaggg ctctggagtc cccagccgct tctctggatc
      121 caaagatgct tcggccaatg cagggatttt gctcatctct gggctccagt ctgaggatga
      181 ggctgactat tactgtatga tttggcacaa caatgcttat gtgttattcg gaggagggac
      241 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000366             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:9674:13520
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000366
VERSION     KCWK01000366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9674:13520"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..436
                     /note="immunoglobulin light chain variable region"
     V_region        112..436
     V_segment       112..399
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66104.1"
                     /translation="DYYCQVWDSSTRYAVF"
     J_segment       406..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           88 a          151 c          138 g           97 t
ORIGIN      
        1 acatggggct gccctgtctg ggtctcagga ggcagcattg acggtgcctc agccatggcc
       61 tggacccttc tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgag
      121 ctgactcagc caccctcatt gccagcggcc tcaggacaga cggccaggat cgcctgtggg
      181 ggagacagca ttggaagtga aaatgtgttc tggtaccagc agaagccacg gcaggcccct
      241 gtcctggtca tctatggtga tacgaaacgg ccctcaggga tccctgagcg attctctggc
      301 tccatctctg ggaacaccgc caccctgacc atcaacaggg tcgaggccgg ggatgaggct
      361 gactattact gtcaggtgtg ggacagtagt actagatacg cggttttcgg cggagggacc
      421 cggctaaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000367             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:14904:2546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000367
VERSION     KCWK01000367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14904:2546"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..430
                     /note="immunoglobulin light chain variable region"
     V_region        102..430
     V_segment       102..396
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66105.1"
                     /translation="DYYCCSRSTSSTYVF"
     J_segment       397..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>470
                     /gene="IGLC"
BASE COUNT           82 a          161 c          114 g          113 t
ORIGIN      
        1 acatgggggg tctcagaagg cagcgctctc aggacgtctc caccatggcc tggactctgc
       61 tcctcgtcac cctcctcact caaggcacag gatcctgggc tcagtctgcc ccgactcagc
      121 ctccctctgt gtctgggtct cctggacagt cggtcaccat ctcctgcact ggaaccagca
      181 gtgacgttgg tggttataac tctgtctcct ggtaccaaca acacccaggc aaagccccca
      241 aagtcatgat ttttggtgtc aataatcggc cctctggggt ctctgaccgc ttctctggct
      301 ccaagtctgg caacacggcc tccctgacca tctctgggct ccagtctgag gacgaggctg
      361 attattactg ttgttcacgt tcaaccagta gcacttacgt cttcggtcct gggacccggc
      421 tcaccgtcct gggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000368             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:13648:21999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000368
VERSION     KCWK01000368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13648:21999"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66106.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           89 a          155 c          126 g          110 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccct ctcctgcact
      181 gggagcagct ccaacattgg agattattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccaaac tcctcatcta tgaaaataat aagcgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctggtac ctcagccccc ctgaccatca ctggactcca gtctgacgat
      361 gaggctgatt attactgtca gtcctatgat agcagcctga gtgttgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000369             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:15952:13926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000369
VERSION     KCWK01000369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15952:13926"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..431
                     /note="immunoglobulin light chain variable region"
     V_region        107..431
     V_segment       107..394
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66107.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           94 a          148 c          122 g          105 t
ORIGIN      
        1 acatggggga gctgtgggct cagaagcaga actctgggtc ctctccacca tggcctggac
       61 ccctcccctg ctcatcctcc tcactctctg cacaggttcc gtggtttcct ctgagctgac
      121 tcaggagcct gcattgtctg tggccttggg acaaacagtc aggatgacct gccaaggaga
      181 cagcctcaaa acctattatg caagctggta ccagcagaag ccaggccagg tccctgtgct
      241 ggtcatctat ggtaacaact accggccctc agggatccca ggccgattct ctgtctcctg
      301 gtcaggaaac acaggttcct tgaccatcac tgcggctcag gtggaagatg aggctgacta
      361 ttactgtaag tcctgggaca gcagtggtac ccattacatc ttcggtgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000370             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:6960:8966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000370
VERSION     KCWK01000370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:6960:8966"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..403
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66108.1"
                     /translation="DYHCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          163 c          114 g          106 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagtcagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacacacac tggtaccaac agaagccagg gagtcccccc cggtatcttc
      241 tgaaatacaa atcagacaca gaccagggcc aggggtctgg agtccccagc cgcttctctg
      301 gatcccaaga tgcttcagcg aacacaggta ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctatcactgt gccattggtc acagcagcgg tccatacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000371             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:9814:5050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000371
VERSION     KCWK01000371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9814:5050"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..406
                     /note="immunoglobulin light chain variable region"
     V_region        88..406
     V_segment       88..374
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66109.1"
                     /translation="DYYCDSWDSSGAQF"
     J_segment       375..406
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           88 a          139 c          119 g           98 t
ORIGIN      
        1 tcagaagcag agctctgggg tgtctccacc atggcctgga ctcctctctg gctcaccctc
       61 ctcagtcttt gcacaggttc tatggtttct tctgagctga ctcaggaccc tgcagtgtct
      121 gtggccttgg gacagacagt caggattacc tgccaaggag acagcctcag aagctcttat
      181 gcaaactggt accaacagag gccaggccag gcccctgtgc tggtcgtcta tggtaacaac
      241 taccggccct cagggatccc agagcgattc tctggctcct actcacgaaa cacagcttcc
      301 ttgaccatct ctggggctca ggtggaagat gaggctgact attactgtga ctcctgggac
      361 agcagcggag cccaattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct
      421 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000372             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:11108:16472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000372
VERSION     KCWK01000372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11108:16472"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66110.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          144 c          132 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca gactctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcgggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000373             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:14137:12029
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000373
VERSION     KCWK01000373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14137:12029"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66111.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           94 a          154 c          126 g          107 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaaggaatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca tgtcagcctc cctggccatc agcgggctcc agaccgagga
      361 tgagggtgat tattactgcg cagcatggga tgatagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01000374             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:11798:11996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000374
VERSION     KCWK01000374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11798:11996"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66112.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          148 c          129 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgatgc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000375             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:5904:15077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000375
VERSION     KCWK01000375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:5904:15077"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66113.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          164 c          120 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgccc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggccagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000376             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:11250:7012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000376
VERSION     KCWK01000376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:11250:7012"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66114.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       411..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          155 c          128 g          113 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggaggt tattatgtgc agtggtacca acagcttcca
      241 ggaacggccc ccaaactcct catctatgaa aatgataaac gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tgattcctca gcctccctga ccgtcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gcttgagtgt tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01000377             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:16849:17288
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000377
VERSION     KCWK01000377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16849:17288"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..403
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66115.1"
                     /translation="VYYCAIGHSSGLYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           88 a          158 c          121 g          113 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctgtct accacgtaca ctggtaccag cagaagccag ggagtccccc ccggtatctt
      241 ctgaggtaca aatcagactc agataagggc cagggctctg gggtccccag ccgcttctct
      301 ggatccagta atgcttcagc gaacacaggg attttacgca tttctgggct ccagtctgag
      361 gatgaggctg tctattactg tgccattggg cacagcagcg gtctttacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000378             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:23606:15493
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000378
VERSION     KCWK01000378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:23606:15493"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..289
                     /note="immunoglobulin light chain variable region"
     V_region        7..289
     V_segment       7..251
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <214..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66116.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       253..289
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           73 a           97 c           93 g           64 t
ORIGIN      
        1 acatggggac agacggccag gatcacctgt gggggagaca acattggaag tcaaagtgtg
       61 cactggtacc agcacaagcc accgcaggcc cctgtactgg tcatctttta ttataccgaa
      121 cggccctcag gaatccctga gcgattctct ggctccaaat cagggaatac cgccaccctg
      181 accatcagcg gggtcgaggc cggggatgag gctgactatt actgtcaggt gtgggacaca
      241 actattgatc acggcttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      301 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000379             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:19225:11949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000379
VERSION     KCWK01000379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19225:11949"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66117.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          157 c          117 g          112 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccccct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacgtacac tggtatcagc ggaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc tgggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aatacaggaa ttttacacat ctctggtttc cagtctgagg
      361 atgaggctga ctattactgt gccattggcc acggtagcgg tgactacatc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000380             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:13173:15119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000380
VERSION     KCWK01000380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13173:15119"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..385
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66118.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       387..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           88 a          147 c          123 g          104 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gcatctgggg cccccgggca gagggtcacc atctcctgca ctgggagcag ctccaacatc
      181 ggggcgggtt tttatgtatc ctggtaccag cagttcccag gaaaagcccc caagctcctc
      241 atctttgaaa ataacaagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggttcctcag cctccctgac catcactgga ctccaatctg aggatgaggc tgattattat
      361 tgttcatcat gggaaagcag cctgaattgg gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000381             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:13504:4104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000381
VERSION     KCWK01000381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13504:4104"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..386
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66119.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          152 c          116 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta ataatgtgtc ctggtaccag cacctcccag gaacagctcc caaactcctc
      241 atctattata atgatcaacg aggctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcgt gggatgatag cctgagtagt tacatcttcg ctgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000382             382 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:19040:9837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000382
VERSION     KCWK01000382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 382)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19040:9837"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..344
                     /note="immunoglobulin light chain variable region"
     V_region        14..344
     V_segment       14..307
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <272..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66120.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       308..344
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>382
                     /gene="IGLC"
BASE COUNT           76 a          121 c           98 g           87 t
ORIGIN      
        1 acatgggggg gctcaggctg ccctgactca gcctccctca atgtctgggt ctcctggaca
       61 gtcggtcacc atctcctaca ctggaaccag cagtgacatt ggtggttata accgtgtctc
      121 ctggtaccaa cagcacccag gcaaagaccc caaattcatg atttatgagg tcagtcaacg
      181 gccctcaggg gtctctgatc gtatctctgg ctccaagtct ggcaacacgg cctccctgac
      241 catctctggg ctccagactg aggatgaggc tggttattac tgcagctcat ttgcaggtac
      301 caacactggc ttaatcggtg gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc
      361 cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000383             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:7480:19125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000383
VERSION     KCWK01000383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7480:19125"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66121.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          157 c          129 g          107 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcagcact cagggacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggcgccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tattgttgct catataggag tggaaacact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000384             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:22831:5572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000384
VERSION     KCWK01000384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22831:5572"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..275
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66122.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       277..314
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           74 a          106 c           92 g           80 t
ORIGIN      
        1 acatggggga gcatcagcca gtctcacatg caccttcagc ggtggcatca atgttgctgt
       61 ctaccacata cactggtacc agcagaagcc agggagtccc ccccggtatc ttctgaggta
      121 caaatcagac tcagataagg gccagggctc tggagtcccc agccgcttct ctggatccag
      181 taatgcttca gcgaacacag ggattttacg catttctggg ctccagtctg aggatgaggc
      241 tgactattac tgtgccattg gacacagcag cggtctttac atcttcggtg ctgggacccg
      301 gctcagcgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01000385             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:21764:17519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000385
VERSION     KCWK01000385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21764:17519"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66123.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           96 a          163 c          112 g          109 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcaa ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctgcct accacataca ctggtaccag cagaagccag ggagtccccc ccggtatctt
      241 ctgacttaca aatcagactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaaa atgcttcaac gaacacaggc attttacaca tctctgggct ccagtctgag
      361 gatgaggctg actatttctg tgccattgga cacagcagcg gtccttacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000386             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:12703:10377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000386
VERSION     KCWK01000386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12703:10377"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66124.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          155 c          119 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgctc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000387             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:8905:5563
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000387
VERSION     KCWK01000387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:8905:5563"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66125.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          155 c          129 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccag cagcttccag
      241 ggacggcccc caaactcctc atctatgaaa atgataaacg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct gattcctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cttgagtgtt gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000388             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:21244:5200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000388
VERSION     KCWK01000388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21244:5200"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..404
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66126.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       410..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           93 a          160 c          120 g          108 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtactga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttgga agtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcaactggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caggtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcagat gtatgacagt agtgatgtat tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01000389             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:16792:15947
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000389
VERSION     KCWK01000389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16792:15947"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66127.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          159 c          114 g          115 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000390             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:16511:13954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000390
VERSION     KCWK01000390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16511:13954"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..408
                     /note="immunoglobulin light chain variable region"
     V_region        78..408
     V_segment       78..369
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66128.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       371..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           79 a          143 c          120 g          104 t
ORIGIN      
        1 acatggggag gacagtctcc agcatggcct ggtctctcct tctcactctg ctggttcact
       61 gcacagggtc ctgggcccag tctgtgctga cgcagccgcc ctcagcatct ggggcccccg
      121 ggcagagggt taccatctcc tgcactggga gcagctccaa catcggggcg ggtttttatg
      181 tgtcctggta ccagcagttc cctgggacag cccccaaact cctcatcttt gaaaataata
      241 agcgaccctc aggggtttct gaccgattct ctggctccaa gtctggttcc tcagcctccc
      301 tgaccatcac tggactccag tctgaggatg aggctgatta ttactgctca tcatgggaaa
      361 gcagcctgaa ttgggtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000391             357 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:15418:5642
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000391
VERSION     KCWK01000391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 357)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15418:5642"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..319
                     /note="immunoglobulin light chain variable region"
     V_region        8..319
     V_segment       8..275
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <247..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66129.1"
                     /translation="DYYCSTYVGSNTYMF"
     J_segment       282..319
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>357
                     /gene="IGLC"
BASE COUNT           70 a          114 c           90 g           83 t
ORIGIN      
        1 acatgggctc cctctgtgtc cgggtctcct ggacagtcgg tcaccatctc ctgcactgga
       61 accagcagtg atattgcgta tgataatgct gtgtcttggt accagcagca tccaggcaag
      121 gcccccaaac tcatgattta tgacgtcagt aagcggccct caggggtctc tgatcgcttc
      181 tcgggctcca agtctggcaa cacggcctcc ctgaccatct ctgggctcca ggctgaggat
      241 gaggctgact attactgcag cacatatgta ggcagcaaca cttacatgtt cgatcctggg
      301 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01000392             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:18010:11538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000392
VERSION     KCWK01000392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18010:11538"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66130.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          141 c          136 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cgaccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000393             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:8686:15375
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000393
VERSION     KCWK01000393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8686:15375"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..442
                     /note="immunoglobulin light chain variable region"
     V_region        118..442
     V_segment       118..404
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66131.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       406..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           96 a          154 c          132 g           98 t
ORIGIN      
        1 acatggggag gaacctgccc agcctgggcc tcaggaggca gcattgacgg tgcctcagcc
       61 atggcctgga cttttctcct cctcggcctc cttgcttact gcacaggctc tgcggcctcc
      121 tatgatctga ctcagccacc ctcggtgtca gtgtccccag gacagacggc caggatcacc
      181 tgtgggggag acaacattgg aagtcaaagt gtgcactggt accagcacaa gccaccgcag
      241 gcccctatac tggtcatctt ttattatacc gaacggccct caggaatccc tgagcgattc
      301 tctggctcca aatcagggaa caccgccacc ctgaccatca gcggggtcga ggccggggat
      361 gaggctgact attactgtca ggtgtgggac acaactattg atcacggctt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000394             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:7908:16109
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000394
VERSION     KCWK01000394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7908:16109"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..441
                     /note="immunoglobulin light chain variable region"
     V_region        94..441
     V_segment       94..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66132.1"
                     /translation="DYYCAIGHSSGNYIF"
     J_segment       408..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          155 c          119 g          114 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctat gctgactcag ccggcctcct
      121 tctcagcatc tcctggagct tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtttcttc
      241 tgagatacaa gtcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaagga tgcttcagtg aacacaggaa ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg taattatatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000395             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:9478:5035
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000395
VERSION     KCWK01000395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9478:5035"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66133.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           92 a          157 c          124 g          113 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cacttcacag ttccagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggagat tattttgtgc agtggtacca gcaccttcca
      241 ggaacggccc ccaaactcct catctatgaa aataataagc gaccctcagg gatttctgat
      301 cgattctctg gctcccagtc tggaacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtttgattgc tgtgttattc
      421 ggaggaggga cccggccgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01000396             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:16151:6193
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000396
VERSION     KCWK01000396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16151:6193"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..254
                     /note="immunoglobulin light chain variable region"
     V_region        13..254
     V_segment       13..217
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <182..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66134.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       218..254
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           58 a           88 c           79 g           67 t
ORIGIN      
        1 acatggggta cactggtacc agcagaagcc agggagtccc ccccggtttc ttctgaggta
       61 caaatcagac tcagataagg gccagggctc tggagtcccc agccgcttct ctggatccag
      121 taatgtttca gcgaacacag ggattttacg catttctggg ctccagtctg aggatgaggc
      181 tgactattac tgtgccattg ggcacagcag cggtccttac atcttcggtg ctgggacccg
      241 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01000397             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:25711:7204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000397
VERSION     KCWK01000397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:25711:7204"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    70..394
                     /note="immunoglobulin light chain variable region"
     V_region        70..394
     V_segment       70..345
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <319..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66135.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       357..394
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>432
                     /gene="IGLC"
BASE COUNT           86 a          136 c          119 g           91 t
ORIGIN      
        1 acatggggag ccatggcctg gacccttctc ctcctcggcc tcctcgctca ctgcacaggc
       61 tctgcgacct cctttgagtt gactcagcca ccctcggtgt cagcggcctc aggacagacg
      121 gccaggatca cctgtggggg agacaacatt ggaattaaat ttgtccactg gtaccagcag
      181 aagccagcgc aggcccctgt gaaggtcatc tatgctgatg acaaacggcc ctcagggatc
      241 cctgagagat tctctggctc caattcaggg aacaccgcca ccctgaccat cagcggggtc
      301 gaggccgggg atgaggctga ttattcctgt caggtgtggg acagtgagac tgattattac
      361 atcttcggta ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      421 actctgttcc cg
//
LOCUS       KCWK01000398             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:8417:5415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000398
VERSION     KCWK01000398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8417:5415"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66136.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          142 c          135 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccaaca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgcggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ctgatcatcc ggtgttgttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000399             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:12054:19906
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000399
VERSION     KCWK01000399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12054:19906"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..266
                     /note="immunoglobulin light chain variable region"
     V_region        8..266
     V_segment       8..229
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66137.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       230..266
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           64 a           91 c           87 g           62 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaagtaa gagtgtgcac tggtaccagc acaagccacc
       61 gcaggcccct atcctggtca tctattatta taccgaacgg ccctcggcga tccctgagcg
      121 attctctggc tccaaatcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggacactact attgatcatg gctttttcgg
      241 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      301 cccg
//
LOCUS       KCWK01000400             495 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:14927:7407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000400
VERSION     KCWK01000400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 495)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14927:7407"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..457
                     /note="immunoglobulin light chain variable region"
     V_region        109..457
     V_segment       109..420
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66138.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       423..457
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        458..>495
                     /gene="IGLC"
BASE COUNT           94 a          168 c          118 g          115 t
ORIGIN      
        1 acatgggtca acgcagagta catgggggca gggaaagagg ctgtgtccac catggcctgg
       61 actcctctcc tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg
      121 acccagccaa cctccctctc agcatctccg ggagcatcag ccagactcag ctgcaccttg
      181 agcagtggca ccaatgttgg tagttacagc attttctggt accagcagaa gccagggagt
      241 cctccccggt accttctcta ctactactca gactcaacta agcaccaggg ctctggagtc
      301 cccagccgct tctctggatc caaagatgct tcagccaatg cagggctttt actgatctct
      361 gggctccagt ctgaggatga ggctgactat tactgtgcca tttggcacag cagcgcttct
      421 tgcatcttcg gtcctgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg
      481 gtcactctgt tcccg
//
LOCUS       KCWK01000401             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:23904:13993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000401
VERSION     KCWK01000401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23904:13993"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66139.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          153 c          120 g          101 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagga atagtgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctggcc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagcggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagcggt tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000402             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:8772:14954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000402
VERSION     KCWK01000402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:8772:14954"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..295
                     /note="immunoglobulin light chain variable region"
     V_region        8..295
     V_segment       8..258
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <220..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66140.1"
                     /translation="DYYCATWDDSLRGYIF"
     J_segment       259..295
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        296..>333
                     /gene="IGLC"
BASE COUNT           68 a          102 c           86 g           77 t
ORIGIN      
        1 acatggggga acagtgtcgc catctcctgt tctggaagca gctccaacat cggaagtcat
       61 agtgtatcct ggtaccagca gctcccagga acagctccca aactcctcat ctattatgat
      121 gatcaacgag cctcgggtgt ctctgaccga ttctctggct ccaggtctgg cacgtcagcc
      181 tccctggcca tcagtgggct ccagaccgag gatgaggctg attattactg cgctacatgg
      241 gatgatagcc tgagaggtta catcttcggt gatgggaccc ggctcaccgt cctaggtcag
      301 cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000403             337 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:13458:7493
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000403
VERSION     KCWK01000403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 337)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 337)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..337
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13458:7493"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..299
                     /note="immunoglobulin light chain variable region"
     V_region        8..299
     V_segment       8..262
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>271
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66141.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       263..299
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        300..>337
                     /gene="IGLC"
BASE COUNT           71 a          102 c           97 g           67 t
ORIGIN      
        1 acatggggtg tccccaggac agacggccag gatcacctgt gggggagaca acattggaag
       61 taagagtgtg cactggtacc agcacaagcc accgcaggcc cctatcctgg tcatctatta
      121 ttataccgaa cggccctcgg cgatccctga gcgattctct ggctccaaat cagggaacac
      181 cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt actgtcaggt
      241 gtgggacact actattgatc atggcttttt cggaggaggg acccggctga ccgtcctagg
      301 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000404             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:23079:6356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000404
VERSION     KCWK01000404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:23079:6356"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66142.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000405             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:19664:13353
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000405
VERSION     KCWK01000405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19664:13353"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66143.1"
                     /translation="DYHCQVYDGSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          160 c          122 g          113 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agtagttacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctacttctcc gactcagaca agcagttggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt actcatctct gggctccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtatgacgg tagtgctgtt ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000406             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:22630:20005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000406
VERSION     KCWK01000406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22630:20005"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66144.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          160 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgtaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaaataaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000407             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:12119:15521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000407
VERSION     KCWK01000407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:12119:15521"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..392
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66145.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       406..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           89 a          152 c          122 g          111 t
ORIGIN      
        1 acatgggggt gggatctcag gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccccgact
      121 cagactccct ctgtgtccgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgata ttgggtatta tcatgctgtg tcttggtacc agcatcatcc aggcaaagcc
      241 cccaaactca tgatttatga ggtcaataaa cggcccgcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccagac tgaggatgag
      361 gctgattatt actgtagctc atatgcaggc agcaacagtt tattcttcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000408             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:13338:17761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000408
VERSION     KCWK01000408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13338:17761"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..426
                     /note="immunoglobulin light chain variable region"
     V_region        104..426
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66146.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       394..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT          101 a          138 c          122 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg aggtgacaca
      121 gtcaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagcaat
      181 actggcaaat aattatgctc agtggttcca gcagaagcca gaccaggccc ctgtgttggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gttgacagca gtgcccatca tccgttattc ggaggaggga cccccgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000409             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:12662:7975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000409
VERSION     KCWK01000409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12662:7975"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66147.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       398..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           86 a          157 c          118 g          112 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgcc ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaagct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtcttat aatgctgtgt cttggtacca acagcgtcca ggcaaagccc
      241 cccaactcat aatttttgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgctgctca tatgtaggca gcaacactta catcttcgat gttgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000410             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:9257:13991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000410
VERSION     KCWK01000410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9257:13991"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66148.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          152 c          114 g          117 t
ORIGIN      
        1 acatgggggc tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttggtaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcatc aggggtctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000411             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:9193:4305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000411
VERSION     KCWK01000411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:9193:4305"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66149.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          143 c          131 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga attgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attgtaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000412             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:7242:15518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000412
VERSION     KCWK01000412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7242:15518"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66150.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           91 a          154 c          120 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc ataatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaga cggcctccct gaccatctct ggactccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacgct ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000413             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15424:15529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000413
VERSION     KCWK01000413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15424:15529"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66151.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          164 c          120 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcaatattg gcaataaaaa catgtactgg taccagcaga agccagggag cgctcccaag
      241 ttcttcctgt actactactc cgactcagac atgcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagcc ctcaagtcat acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctgt attattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01000414             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:19567:7210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000414
VERSION     KCWK01000414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19567:7210"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66152.1"
                     /translation="DYYCQVYDSGANVSF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          167 c          123 g          106 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggct ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagcgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tggtgctaat gtgtcattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000415             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:7779:14001
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000415
VERSION     KCWK01000415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7779:14001"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66153.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          161 c          123 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagtcac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000416             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:24472:13236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000416
VERSION     KCWK01000416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24472:13236"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    33..357
                     /note="immunoglobulin light chain variable region"
     V_region        33..357
     V_segment       33..319
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <282..>329
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66154.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       321..357
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        358..>395
                     /gene="IGLC"
BASE COUNT           83 a          123 c          109 g           80 t
ORIGIN      
        1 acatgggtgc ttactgcaca ggctctgcgg cctcctatga tctgactcag ccaccctcgg
       61 tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac attggaagtc
      121 aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc atcttttatt
      181 ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca gggaacaccg
      241 ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac tgtcaggtgt
      301 gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc gtcctaggtc
      361 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000417             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:20226:7300
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000417
VERSION     KCWK01000417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20226:7300"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66155.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          140 c          137 g          101 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtgga ggagacaaca
      181 ttggaagtga agttgtcaac tggtaccagc agaggccacc gcaggcccct gtggtggtca
      241 tctatgctga ttatgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcggag tcgaggccgg ggatgaggct gactattatt
      361 gtcaggtgtg ggacatttat attgaccatc cggtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000418             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:22694:13934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000418
VERSION     KCWK01000418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22694:13934"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..417
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66156.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       418..454
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           92 a          158 c          126 g          116 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact tcacagttcc agggtcctgg
      121 gcccagtctg tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc
      181 atctcctgca ctgggagcag ctccaacatt ggagattatt ttgtgcagtg gtaccagcac
      241 cttccaggaa cggcccccaa actcctcatc tatgaaaata ataagcggcc ctcagggatt
      301 tctgatcgat tctctggctc ccagtctgga acctcagcct ccctgaccat cactggactc
      361 cagtctgagg atgaggctga ttattactgc cagtcctatg acagcagttt gattgctgtg
      421 ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCWK01000419             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:21517:12174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000419
VERSION     KCWK01000419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21517:12174"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66157.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          149 c          138 g           94 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaac taaatatgtc cactggtacc agcagaagcc agcgcaggcc cctgtgttgg
      241 tcatctatgc tgatagcaga cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggagcac cgccaccctg accatcagcg gggtcgaggc cgggtatgag gctgactatt
      361 tctgtcaggt gtgggacgat agtagtgatc atccggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000420             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:20208:19342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000420
VERSION     KCWK01000420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20208:19342"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66158.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       414..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           97 a          158 c          125 g          108 t
ORIGIN      
        1 acatggggga agcgcagctt cagctgtggg tacagaaggc aggactcagg acaatctcca
       61 gcatggcctg gttccctctc gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc
      121 agtctgtgct gactcagcct ccctcagcgt ctgaggccgc caggaagagt gtcaccatct
      181 cctgttctgg aagcagctcc aacatcggaa gtaataatgt gtcctggtac cagcacctcc
      241 caggaacagc tcccaaactc ctcatctatt ataatgatca acgaggctca ggtgtctctg
      301 accgattctc tggctccaag tctggcacgt cagcctccct ggccatcagt gggctccaga
      361 ccgaggatga ggctgattat tactgcgcag cgtgggatga tagcctgagc agttacatct
      421 tcgctgctgg gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCWK01000421             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:24061:11336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000421
VERSION     KCWK01000421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24061:11336"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66159.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          143 c          132 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagtggc ctcaggacag ccggccagga tcacctgtgg gggagacgac
      181 attggaacta aaactgtaca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000422             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:13590:4409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000422
VERSION     KCWK01000422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13590:4409"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66160.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       390..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          147 c          120 g          104 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagaactct gggtcctctc caccatggcc tggacccctc
       61 ccctgctcat cctcctcact ctctgcacag gttccgtggt ttcctctgag ctgactcagg
      121 agcctgcatt gtctgtggcc ttgggacaaa cagtcaggat gacctgccaa ggagacagcc
      181 tcaaaaccta ttatgcaagc tggtaccagc agaagccagg ccaggtccct gtgctggtca
      241 tctatggtaa caactaccgg ccctcaggga tcccaggccg attctctgtc tcctggtcag
      301 gaaacacagg ttccttgacc atcactgcgg ctcaggtgga agatgaggct gactattact
      361 gtaagtcctg ggacagcagt ggtacccatt acatcttcgg tgctgggacc cggctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000423             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:28271:7128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000423
VERSION     KCWK01000423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:28271:7128"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66161.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           91 a          155 c          119 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tggactcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000424             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:7370:9354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000424
VERSION     KCWK01000424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7370:9354"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66162.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           89 a          165 c          112 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaccaatg
      181 ttggtagtta cagcattttc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca actaagcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccatttggc acagcagcgc ttcttgcatc ttcggtcctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000425             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:18828:5918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000425
VERSION     KCWK01000425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18828:5918"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66163.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          157 c          127 g          108 t
ORIGIN      
        1 catgggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtcc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa cagtgtcgcc atctcctgtt
      181 ctggaggcag ctccaacatc ggaagtcata gtgtatcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatgatg atcaacgagc ctcaggtgtc tctggccgat
      301 tctctggctc caggtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagaggttac atcttcggtg
      421 atgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01000426             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:9547:10046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000426
VERSION     KCWK01000426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9547:10046"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66164.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          162 c          115 g          108 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatccac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagtaacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcaacg aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattgggc acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000427             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:8397:3614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000427
VERSION     KCWK01000427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8397:3614"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..404
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66165.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       406..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           92 a          160 c          121 g          108 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtactga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc caggctcccc tgcaccctga gcagtgacct
      181 cagtgttgga agtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcaactggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcagat gtatgacagt agtgatgtgt tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01000428             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:15769:9248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000428
VERSION     KCWK01000428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:15769:9248"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-38"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66166.1"
                     /translation="DYYCYSGDDNNHDVF"
     J_segment       385..422
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           94 a          137 c          121 g          108 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgaacgtctc accatggcct ggatccctct
       61 cctgctcccc ctcctcgctc tctgcacagt ctctgtggct tcctatgaac tgacacagcc
      121 accctcggtg tcagtgtctc ccggacagac ggccaagatc acctgctctg gagaaatatt
      181 gacaaaaaaa tttgtttggt ggttccagca gaagccaggc caggcccctg tgttggtaat
      241 ttataaagac agtgagcgcc cctcagggat tcctgaacgt ttctctggct ccagctcagg
      301 gaccacagtc accctgaccg tcagtggggc ccaggctgag gatgaggctg actattactg
      361 ttactctggg gatgacaaca atcatgatgt gttcggaagt ggcaccaagt tgaccgtcct
      421 cggtcagccc aaggcttccc ccttggtcac tctgttcccg
//
LOCUS       KCWK01000429             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:16552:23613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000429
VERSION     KCWK01000429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16552:23613"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..425
                     /note="immunoglobulin light chain variable region"
     V_region        95..425
     V_segment       95..386
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66167.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       388..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          148 c          121 g          107 t
ORIGIN      
        1 acatggggag gaggcagcac tcaggacagt ctccagcatg gcctggtctc ctctcctcct
       61 cacccttctc attcactgca cagggtcctg ggcccagtct gtgctgacgc agccgccctc
      121 agtgtctggg gcgcccgggc agagggtcac catctcctgc actgggagca gctccaacat
      181 tggaggttat tatgtgcagt ggtaccagca gcttccagga acggccccca aactcctcat
      241 ctatgaaaat gataaacgac cctcaggggt ttctgatcga ttctctggct cccagtctga
      301 ttcctcagcc tccctgacca tcactggact ccagtctgag gatgaggctg attattactg
      361 ccagtcctat gacagcagct tgagtgttgt gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000430             397 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:18633:5893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000430
VERSION     KCWK01000430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 397)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18633:5893"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    29..359
                     /note="immunoglobulin light chain variable region"
     V_region        29..359
     V_segment       29..320
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66168.1"
                     /translation="DYYCGAWDSSLSGYIF"
     J_segment       322..359
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>397
                     /gene="IGLC"
BASE COUNT           76 a          129 c          105 g           87 t
ORIGIN      
        1 acatgggcac tgcacagggt cctgggccca gtctgtcctg acgcagccgc cctcagtgtc
       61 tgcggcccca gggcagaagg tcaccatctc ctgctctgga agtagctcca acatcgggag
      121 aaattctgtc tcctggtacc agcaggtccc aggaacggcc cccaaactcc tcacctatga
      181 caatgataag cgaccctcag gggtttctga ccgattctct ggctccaagt ctggttcctc
      241 agcctccctg gccatcactg gactccagac tggagatgag gctgattatt actgcggagc
      301 atgggatagc agtctgagtg gttacatttt cggtgctggg acccggctca ccgtcctagg
      361 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01000431             496 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:4903:7897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000431
VERSION     KCWK01000431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 496)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:4903:7897"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..458
                     /note="immunoglobulin light chain variable region"
     V_region        110..458
     V_segment       110..421
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>430
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66169.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       424..458
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        459..>496
                     /gene="IGLC"
BASE COUNT           93 a          168 c          124 g          111 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      181 gagcagtgac ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag
      241 cgctcccagg ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt
      301 ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc
      361 tgggctccag cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctaa
      421 tgtcttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      481 ggtcactctc ttcccg
//
LOCUS       KCWK01000432             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:16972:16480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000432
VERSION     KCWK01000432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16972:16480"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66170.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           91 a          156 c          117 g          110 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcatctcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 gtctaccaca tacactggta ccagcagaag ccagggagtc ccccccggta tcttctgagg
      241 tacaaatcag actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 agtaatgctt cagcgaacac agggatttta cgcatttctg ggctccagtc tgaggatgag
      361 gctgactatt actgtgccat tggacacagc agcggtcttt acatcttcgg tgctgggacc
      421 cggctcagcg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000433             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:13916:12347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000433
VERSION     KCWK01000433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13916:12347"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66171.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       403..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           87 a          158 c          125 g          106 t
ORIGIN      
        1 acatgggggg ctggggtctc aggaggcagc gctctcggga catctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccctga
      121 ctcagcctcg ctcagtgtct gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga catcggtggt tataactatg tctcctggta ccaacagcat ccaggcacag
      241 cccccaaagt catgatttat gaggtcagta agcggccctc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag gctgaggacg
      361 aggctgatta ttactgcagc tcatatacag gcatcaacag ttacatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000434             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:6220:5421
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000434
VERSION     KCWK01000434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6220:5421"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66172.1"
                     /translation="DYYCAAWDDRLTGYVF"
     J_segment       415..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          157 c          127 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cgggagcaat agtgtatcct ggtaccagct gctcccagaa
      241 acggctccca aactcctcat ctattataat aatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgagggtg attattactg cgcagcatgg gatgatcgcc tgaccggtta cgtgttcggt
      421 gttgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000435             318 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18573:11794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000435
VERSION     KCWK01000435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 318)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18573:11794"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..280
                     /note="immunoglobulin light chain variable region"
     V_region        1..280
     V_segment       1..243
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>252
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66173.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       244..280
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        281..>318
                     /gene="IGLC"
BASE COUNT           66 a           97 c           78 g           77 t
ORIGIN      
        1 acatggggca gtggcaatgt tggtagttac agcatattct ggtaccagca gaagccaggg
       61 agtcctcccc ggtaccttct ttactactac tcagactcaa gtaaccacca ggactctgga
      121 gtccccagcc gcttctctgg atcgaaagat gcttcagcca atgcagggct tttactgatc
      181 tctgggctcc agtctgaaga tgaggctgac tattactgtg ccacatggca cagcagcgct
      241 tcttacatct tcggtgctgg gacccggctc accgtcctag gtcagcccaa ggcttccccc
      301 acggtcactc tgttcccg
//
LOCUS       KCWK01000436             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:24466:5880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000436
VERSION     KCWK01000436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:24466:5880"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66174.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       398..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          155 c          122 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctaca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagaccc
      241 caaattcatg atttatgagg tcagtcaacg gccctccggg gtctctgatc gtatctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tggttattac tgcagctcat ttgcaggtac caacactggc ttaatcggtg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000437             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10233:7372
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000437
VERSION     KCWK01000437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10233:7372"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66175.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          152 c          121 g          112 t
ORIGIN      
        1 acatgggggc ttggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggagtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatggagg cagcaatagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000438             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:17071:18018
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000438
VERSION     KCWK01000438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17071:18018"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66176.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          147 c          130 g           97 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gttctggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg aatctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaagt cttgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000439             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:10655:15188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000439
VERSION     KCWK01000439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10655:15188"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..396
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66177.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       398..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           87 a          151 c          118 g          113 t
ORIGIN      
        1 acatggggat ctcaggaggc agcgctctca ggacttctcc accatggtct gggctctgct
       61 cctcctcacc ctcctcactc agggcacagg atcctgggtt caggctgccc cgactcagcc
      121 tccctctgtg tccgggtctc ctggacagtc ggtcaccatc tcctgcactg gaaccagcag
      181 tgatattggg tattataacg ctgtgtcttg gtaccaacag catccaggca aagcccccaa
      241 actcataatt tttgacgtca ttaagcggcc ctcaggggtc tctgatcgct tctctggctc
      301 caagtctggc gacacggcct ccctgaccat ctctgggctc cgggctgagg atgaggctga
      361 ttattactgc agctcatatg caggcagaaa taatttttta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000440             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12402:4405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000440
VERSION     KCWK01000440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12402:4405"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66178.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          142 c          141 g           91 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tggaagtgaa gttgtgaact ggtaccagaa gaagccagcg caggcccctg cactggtcat
      241 ctatgctgat agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcaggggggt cgaggccggg ggtgaggctg actattactg
      361 tcaggtgtgg gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000441             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:9313:9785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000441
VERSION     KCWK01000441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9313:9785"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..410
                     /note="immunoglobulin light chain variable region"
     V_region        80..410
     V_segment       80..375
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <338..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66179.1"
                     /translation="DYYCSSYAGSNSLVF"
     J_segment       380..410
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>448
                     /gene="IGLC"
BASE COUNT           86 a          146 c          113 g          103 t
ORIGIN      
        1 acatgggggg gacatctcca ccatggcctg ggatctgctc ctcttcaccc tcctcactca
       61 gggcacagga tcctgggctc aggctgtcct gactcagcct ccctcaatgt ctgggtctcc
      121 tggacagtcg gtcaccatct cctgcactgg aaccagcagt gacattggta gttataaccg
      181 tgtctcctgg taccaacatc acccagacaa agcccccaaa gtcatgattt atgagggcag
      241 tcagcggccc tcaggggtct ctgatcgctt ctctgcctcc aagtctggca aaacggcctc
      301 cctgaccatc tctgggctcc aggctgagga tgaggctgat tattactgca gctcatatgc
      361 aggcagcaat agtttggttt tcggcggagg gacccggcta accgtcctag gtcagcccaa
      421 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000442             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:5109:4874
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000442
VERSION     KCWK01000442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:5109:4874"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..343
                     /note="immunoglobulin light chain variable region"
     V_region        13..343
     V_segment       13..306
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <268..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66180.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       307..343
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>381
                     /gene="IGLC"
BASE COUNT           76 a          118 c           99 g           88 t
ORIGIN      
        1 acatgggggg cccagtctgt gctgacgcag ccgccctcag tgtctggggc gcccgggcag
       61 agggtcacca tctcctgcac tgggagcagc tccaacattg gagattattt tgtgcagtgg
      121 taccagcacc ttccaggaac ggcccccaaa ctcctcatct atgaaaataa taagcgaccc
      181 tcagggattt ctgatcgatt ctctggctcc cagtctggaa cctcagcctc cctgaccatc
      241 actggactcc agtctgagga tgaggctgat tattactgcc agtcctatga cagcagtttg
      301 attgctgtgt tattcggagg agggacccga ctgaccgtcc taggtcagcc caaggctgcc
      361 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000443             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12829:13168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000443
VERSION     KCWK01000443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12829:13168"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66181.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          158 c          116 g          113 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcaag ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtctt ataatgctgt gtcctggtac caacagcatc caggcaaagc
      241 cccccaactc ataatttttg aggtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgctgct catatgtagg cagcaacact tacatcttcg atattgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000444             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12766:3718
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000444
VERSION     KCWK01000444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12766:3718"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66182.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           91 a          155 c          119 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc ataatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct ggactccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacgct ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000445             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10445:4457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000445
VERSION     KCWK01000445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10445:4457"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..404
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66183.1"
                     /translation="DYYCAAWDDSLRSYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          156 c          125 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctactataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgaggagtta catcttcgct
      421 gctgggaccc gggtcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000446             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:16212:7537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000446
VERSION     KCWK01000446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16212:7537"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..271
                     /note="immunoglobulin light chain variable region"
     V_region        8..271
     V_segment       8..234
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <199..>243
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66184.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       235..271
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        272..>309
                     /gene="IGLC"
BASE COUNT           65 a           94 c           80 g           70 t
ORIGIN      
        1 acatgggctg gaaccagcag tgacattggt ggttataacc gtgtctcctg gtaccaacag
       61 cacccaggca aagaccccaa attcatgatt tatgaggtca gtcaacggcc ctcaggggtc
      121 tctgatcgta tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc
      181 cagactgagg atgaggctgg ttattactgc agctcatttg caggtaccaa cactggctta
      241 atcggtggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      301 ctcttcccg
//
LOCUS       KCWK01000447             326 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:11541:7128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000447
VERSION     KCWK01000447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 326)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11541:7128"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..288
                     /note="immunoglobulin light chain variable region"
     V_region        8..288
     V_segment       8..252
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>260
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66185.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       253..288
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        289..>326
                     /gene="IGLC"
BASE COUNT           68 a          103 c           81 g           74 t
ORIGIN      
        1 acatgggggt caccatctcc tgcactggaa ccagcagtga catcggtggt tataactatg
       61 tctcctggta ccaacagcat ccaggcacag cccccaaagt catgatttat gaggtcagta
      121 agcggccctc aggggtctct gatcgcttct ctggctccaa gtctggcaac acggcctccc
      181 tgaccatctc tgggctccag gctgaggacg aggctgatta ttactgcagc tcatatacag
      241 gcatcaacag ttacatcttc ggtggtggga cccggctcac cgtcctaggt cagcccaagg
      301 cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000448             451 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:4788:15127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000448
VERSION     KCWK01000448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 451)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:4788:15127"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..413
                     /note="immunoglobulin light chain variable region"
     V_region        92..413
     V_segment       92..377
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66186.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       381..413
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>451
                     /gene="IGLC"
BASE COUNT           91 a          140 c          129 g           91 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacccttc tcctcctcgg
       61 cctcctcgct tactgcacag actctgcgac ctcctatgaa ttgactcagt cgccctcagt
      121 gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacgaca ttggaactaa
      181 aactgtgcac tggtaccaac agaagccacc gcagggccct ctattggtca tctttgctga
      241 tagtagacgg ccctcaggga tccctgagcg attctctggc tccaactcag ggaacaccgc
      301 caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg
      361 ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaagcgtcc taggtcagcc
      421 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000449             376 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:21071:4916
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000449
VERSION     KCWK01000449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 376)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:21071:4916"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..338
                     /note="immunoglobulin light chain variable region"
     V_region        8..338
     V_segment       8..301
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <269..>310
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66187.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       302..338
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        339..>376
                     /gene="IGLC"
BASE COUNT           79 a          118 c           97 g           82 t
ORIGIN      
        1 acatgggcag ccaccctccc tgtctgcatc cccgggagca tcggccagac tcccctgcac
       61 cctgagcagt gacctcagtg ttggtaataa aaacatgtac tggtaccaac agaagccagg
      121 gagcgctccc aggttattcc tgtactacta ctccgactca gacaagcagc tgggacctgg
      181 ggtccccaat cgagtctctg gctccaagga gacctcaact aacacagcgt ttttggtcat
      241 ctctgggctc cagcctgagg acgaggccga ttattactgt caggtgtttg acagtagtgc
      301 tgtgttattc ggaggaggga cccgactgac cgtcctaggt cagcccaagg ctgccccctc
      361 ggtcactctc ttcccg
//
LOCUS       KCWK01000450             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:19831:14121
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000450
VERSION     KCWK01000450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19831:14121"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66188.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           81 a          158 c          126 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttctg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg cccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattat tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000451             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:17449:2119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000451
VERSION     KCWK01000451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17449:2119"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..278
                     /note="immunoglobulin light chain variable region"
     V_region        8..278
     V_segment       8..241
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <206..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66189.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       244..278
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>316
                     /gene="IGLC"
BASE COUNT           64 a           98 c           78 g           76 t
ORIGIN      
        1 acatgggggc accaatgttg gtagttacag gatattctgg taccagcaga agccagggag
       61 tcctccccgg taccttctgt actactactc agactcaact aagcaccagg gctctggagt
      121 ccccagccgc ttctctggat ccaaagatgc ttcagccaat gcagggcttt tactgatctc
      181 tgggctccag tctgaagatg aggctgacta ttactgtgcc atatggcaca gcagcgcttc
      241 ttgcatcttc ggtcctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac
      301 ggtcactctg ttcccg
//
LOCUS       KCWK01000452             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:10607:6785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000452
VERSION     KCWK01000452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:10607:6785"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66190.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          147 c          130 g           98 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctccgatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa gagtgtgcac tggtaccaac acaagccacc gcaggcccct atcctggtca
      241 tctattatta taccgaacgg ccctcggcga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacactact attgatcatg gctttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000453             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:22548:15693
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000453
VERSION     KCWK01000453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22548:15693"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66191.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       390..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           88 a          140 c          138 g           96 t
ORIGIN      
        1 acatggggga ctttgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctttacaggc tctgcggcct cctatgcggt gactcagcca
      121 cgctcagtgt ccgtgtcccc aggacaggcg gccaggatca cctgtggggg agacaacatt
      181 ggaagtaaaa gtgtccagtg gtaccagcag acgccaccgc aggcccctgt actggtcatt
      241 tatggtgata gggaacggcc ctcagggatc cctgaacgat tctctggctc caactcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg atagtagtag taaatatgtc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000454             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:22394:9074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000454
VERSION     KCWK01000454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:22394:9074"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66192.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          157 c          122 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca actccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000455             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17916:10252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000455
VERSION     KCWK01000455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17916:10252"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66193.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          151 c          122 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atggaggcag caatagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000456             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:16246:13628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000456
VERSION     KCWK01000456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16246:13628"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66194.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          153 c          119 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctctcagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag tctgagcggt tacatcttcg gcgctgggac ccggctcgcc
      421 gtcctaggtc agtccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000457             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:15096:4226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000457
VERSION     KCWK01000457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15096:4226"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..358
                     /note="immunoglobulin light chain variable region"
     V_region        28..358
     V_segment       28..323
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <286..>330
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66195.1"
                     /translation="DYYCSSYAGSNTLVF"
     J_segment       324..358
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        359..>396
                     /gene="IGLC"
BASE COUNT           76 a          129 c          103 g           88 t
ORIGIN      
        1 acatgggagg gcacaggatc ctgggctcag gctgccctga ctcagcctcc ctcaatgtct
       61 gggtctcctg gacagtcggt caccatctcc tgcactggaa ccgccagtga cattggtgct
      121 tctaaccgtg tctcctggta ccaacatcac ccagacaaag cccccaaagt aatgatttat
      181 gagggcagtc agcggccctc aggggtctct gatcgcttct ctggctccaa gtctggcaac
      241 acggcctccc tgaccatctc tgggctccag gctgaggatg aggctgatta ttactgcagc
      301 tcatatgccg gcagcaatac tttggtattc ggcggaggga cccggctaac cgtcctaggt
      361 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000458             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18155:9474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000458
VERSION     KCWK01000458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18155:9474"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66196.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       409..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           95 a          154 c          118 g          113 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcact
      181 gttgctggct accatatata ttggtaccag cagaagccag ggagtccccc ccggtatctt
      241 ctgaggtaca aatcagactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc gaacacaggg attttacgca tatctggact ccagtctgag
      361 gatgaggctg actattactg tgccattgga cacagcagcg gtgattatat cttcggtgct
      421 gggacccgtc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000459             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:11277:10033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000459
VERSION     KCWK01000459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11277:10033"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..444
                     /note="immunoglobulin light chain variable region"
     V_region        96..444
     V_segment       96..406
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66197.1"
                     /translation="DYHCAIGHSSGPYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           97 a          167 c          112 g          106 t
ORIGIN      
        1 acatggggcc cactgtgggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctccaagcc tatgctgact cagccggcct
      121 ccctctcagc atctcctgga gcatcagtca gtctcacatg caccttcagc ggtggcatca
      181 atgttgctga ctaccacaca cactggtacc aacagaagcc agggagtccc ccccggtatc
      241 ttctcaaata caaatcagac acagaccagg gccaggggtc tggagtcccc agccgcttct
      301 ctggatccaa agatgcttca gcgaacacag gtattttacg catctctggc ctccagtctg
      361 aggatgaggc tgactatcac tgtgccattg gtcacagcag cggtccatac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01000460             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:24619:16006
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000460
VERSION     KCWK01000460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24619:16006"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66198.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       411..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          156 c          127 g          113 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccctctcc
      181 tgcactggga gcagctccaa cattggagat tattatgtgc agtggtacca gcagcttcca
      241 ggaacggccc ccaaactcct catctatgaa aataataagc gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gacgatgagg ctgattatta ctgtcagtcc tatgatagca gcctgagtgt tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01000461             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:13519:13110
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000461
VERSION     KCWK01000461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13519:13110"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..432
                     /note="immunoglobulin light chain variable region"
     V_region        111..432
     V_segment       111..396
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66199.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       400..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           91 a          148 c          135 g           96 t
ORIGIN      
        1 acatgggggg ccctgtctgg gtctcaggag gcagcattga cggtgcctca gccatggcct
       61 ggacccttct cctcctcggc ctcctcgctt actgcacagc ctctgcgacc tcctatgaac
      121 tgactcagcc accctcagtg tcagcggcct caggacagac ggccaggatc acctgtgggg
      181 gagacaacat tggaattaaa actgtgcact ggtaccgcca gaagccagcg cagggccctg
      241 tattggtcat ttttgctgat agcatccggc cctcagggat ccctgagcga ttctctggct
      301 ccaactcagg gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg
      361 actattactg tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc
      421 taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000462             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:3986:9839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000462
VERSION     KCWK01000462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:3986:9839"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66200.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          157 c          127 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcac agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcgggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000463             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:14540:6169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000463
VERSION     KCWK01000463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14540:6169"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66201.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          141 c          136 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc aatgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000464             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:9832:8867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000464
VERSION     KCWK01000464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:9832:8867"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66202.1"
                     /translation="EYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           85 a          159 c          119 g          105 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtgggcac
      181 tatagttata ccatcgcatg gcatcaacaa tatcaaggga aggcccctcg gttcttgatg
      241 tggcttaaaa gtgatggcag ccacaccaag ggggacggga tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctctcc atctccaacc tccagtctga ggatgaggct
      361 gagtattact gtcagacctg ggacattggc atttgggtat tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000465             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:9212:17929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000465
VERSION     KCWK01000465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9212:17929"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66203.1"
                     /translation="DYFCQVWDSISDHPLF"
     J_segment       392..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          148 c          134 g           92 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag cctctgcgac ctcctatgag ctgactcagc
      121 caccctcggt gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa atatgtgcac tggtaccagc agaagccagc gcaggcccct gtgcaggtca
      241 tttatggtga taccaaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactatttct
      361 gtcaggtgtg ggacagtatt agtgatcatc ccttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000466             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:14154:12291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000466
VERSION     KCWK01000466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14154:12291"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..440
                     /note="immunoglobulin light chain variable region"
     V_region        92..440
     V_segment       92..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66204.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       407..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           95 a          155 c          118 g          110 t
ORIGIN      
        1 acatgggact gtggggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc caagcctatg ctgactcagc cggcctccct
      121 ctcagcatct cctggagcat cagccagtct cacatgcacc ttcagcggtg gcatcaatgt
      181 tgctggctac cacatatact ggtaccagca gaagccaggg agtccccccc ggtatcttct
      241 gaggtacaaa tcagactcag ataagggcca ggggtctgga gtccccagcc gcttctctgg
      301 atccaaagat gcttcagcga acacagggat tttacgcatc tctggactcc agtctgagga
      361 tgaggctgac tattactgtg ccatcggaca cagcagcggt gattatatct tcggtgctgg
      421 gacccggctc atcgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01000467             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:22304:6727
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000467
VERSION     KCWK01000467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22304:6727"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66205.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          148 c          130 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cggccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000468             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:7846:21855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000468
VERSION     KCWK01000468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:7846:21855"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66206.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       409..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           90 a          156 c          128 g          107 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcctcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaatag tgtttcctgg taccagcagc tcccagaaac
      241 ggctcccaaa ctcctcatct tttataatga tcggcgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agcggtccgg tattcggcgg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01000469             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:6722:13613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000469
VERSION     KCWK01000469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:6722:13613"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66207.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          161 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tatctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000470             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:18024:17319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000470
VERSION     KCWK01000470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:18024:17319"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66208.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          146 c          131 g           97 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctttga gttgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaatta aatttgtcca ctggtaccag cagaagccag cgcaggcccc tgtgaaggtc
      241 atctatgctg atgacaaacg gccctcaggg atccctgaga gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattcc
      361 tgtcaggtgt gggacagtga gactgattat tacatcttcg gtactgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000471             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:16627:11355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000471
VERSION     KCWK01000471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16627:11355"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66209.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          161 c          120 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg tcagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000472             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:2171:11576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000472
VERSION     KCWK01000472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:2171:11576"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66210.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          138 c          135 g          105 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagtatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggaaag acggccagga tcacctgtgg gggagacaat
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tattgatcat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000473             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:12763:14454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000473
VERSION     KCWK01000473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12763:14454"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66211.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          144 c          135 g          101 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ctactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtcaa ctggtaccaa cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgcggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tactgatcat ccggtgttgt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000474             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:12333:11120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000474
VERSION     KCWK01000474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12333:11120"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..389
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66212.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           89 a          152 c          121 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggactct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 actccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgatattg ggtattatca tgctgtgtct tggtaccagc atcatccagg caaagccccc
      241 aaactcatga tttatgaggt caataaacgg cccgcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 gattattact gtagctcata tgcaggcagc aacagtttat tcttcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000475             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:16228:4201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000475
VERSION     KCWK01000475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16228:4201"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..440
                     /note="immunoglobulin light chain variable region"
     V_region        110..440
     V_segment       110..401
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66213.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       403..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           87 a          152 c          128 g          111 t
ORIGIN      
        1 atgggggctt cagctgtggg cacaggaggc agcactcagg acagtctcca gcatggcctg
       61 gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc agtctgtgct
      121 gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct cctgcactgg
      181 gagcagctcc aacattggag gttattatgt gcagtggtac cagcagcttc caggagcggc
      241 ccccaaactc ctcatctatg aaaatgataa acgaccctca ggggtttctg atcgattctc
      301 tggctcccag tctgattcct cagcctccct gaccatcact ggactccagt ctgaggatga
      361 ggctgattat tactgccagt cctatgacag cagcttgagt gttgtgttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000476             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:14565:18907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000476
VERSION     KCWK01000476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14565:18907"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66214.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       402..439
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           93 a          151 c          118 g          115 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttctctctcg cagcctgtgc tgactcagcc aacctccctc
      121 tcagcttctc ctggagcatc agccagactc acctgcacct tgagcagtgg catcagtgtt
      181 ggtacttaca ggatattctg gtaccagcag aggccaggga gtcctccccg gtatcttctg
      241 aaccaccaca cagactcaga taaacatcag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcggccaa tgcagggatt ttgctcatct ctgggctcca gtctgaggat
      361 gaggctgact attactgtat gatttggcac aacaatgctt atgtgttatt cggaggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000477             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:22354:8475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000477
VERSION     KCWK01000477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22354:8475"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66215.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           96 a          138 c          125 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagacacatt
      181 gccaaaaaaa tatgcttatt ggttccagcg gaaggcaggc cagtcccctg tgctgatcat
      241 ctatgaggac aacaaacggt cttctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtaatggctt attcggagga gggacccgac tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000478             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:4187:11755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000478
VERSION     KCWK01000478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4187:11755"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66216.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          139 c          135 g          104 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggaaag acggccagga tcacctgtgg gggagacaat
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tattgatcat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000479             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:20437:13825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000479
VERSION     KCWK01000479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20437:13825"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66217.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          144 c          139 g           92 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccagcg cacgcccctg tgctggtcat
      241 ctatgctaat agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg ggtgaggctg actattactg
      361 tcaggtgtgg gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000480             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:21692:6936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000480
VERSION     KCWK01000480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21692:6936"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..392
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66218.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       394..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          149 c          123 g          107 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctcctct
       61 cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc tgacgcagcc
      121 gccctcagtg tctggggcgc ccgggcagag ggtcaccatc tcctgcactg ggagcagctc
      181 caacattgga gattattatg tgcagtggta ccagcagctt ccaggaacgg cccccaaact
      241 cctcatctat gaaaatgata aaagaccctc aggggtttct gatcgattct ctggctccca
      301 gtctgattcc tcagcctccc tgaccatcac tggactccag tctgaggatg aggctgatta
      361 ttactgccag tcctatgaca gcagcttgag tgttgtgtta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000481             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:10463:8448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000481
VERSION     KCWK01000481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:10463:8448"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..265
                     /note="immunoglobulin light chain variable region"
     V_region        1..265
     V_segment       1..216
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66219.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       228..265
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           66 a           87 c           86 g           64 t
ORIGIN      
        1 acatgggggg gagacaacat tggaattaaa tttgtccact ggtaccagca gaagccagcg
       61 caggcccctg tgaaggtcat ctatgctgat gacaaacggc cctcagggat ccctgagaga
      121 ttctctggct ccaattcagg gaacaccgcc accctgacca tcagcggggt cgaggccggg
      181 gatgaggctg actattcctg tcaggtgtgg gacagtgaga ctgattatta catcttcggt
      241 tctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      301 ccg
//
LOCUS       KCWK01000482             379 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:17707:19620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000482
VERSION     KCWK01000482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 379)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 379)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..379
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17707:19620"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..341
                     /note="immunoglobulin light chain variable region"
     V_region        20..341
     V_segment       20..305
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <269..>313
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66220.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       309..341
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        342..>379
                     /gene="IGLC"
BASE COUNT           82 a          112 c          110 g           75 t
ORIGIN      
        1 acatgggggc tctgcgacct cctatgaatt gactcagtca ccctcagtgt cagcggcctc
       61 aggacagccg gccaggatca cctgtggggg agacaacatt ggaactaaaa ctgtgcactg
      121 gtaccaacag aagccaccgc agggccctgt attggtcatc tttgctgata gtagacggcc
      181 ctcagggatc cctgagcgat tctctggctc caactcaggg aacaccgcca ccctgaccat
      241 cagcagggtc gaggccgggg atgaggctga ctattactgt caggtgtggg acagtagtag
      301 taaatggata ttcggcgggg ggacccggct aaccgtccta ggtcagccca aggctgcccc
      361 ctcggtcact ctcttcccg
//
LOCUS       KCWK01000483             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:17924:9844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000483
VERSION     KCWK01000483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17924:9844"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66221.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          160 c          114 g          115 t
ORIGIN      
        1 acatgggggc tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt actgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcgtattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctggggtc cagtctgagg
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggtt caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000484             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11747:17772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000484
VERSION     KCWK01000484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11747:17772"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66222.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       410..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          161 c          124 g          107 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctcgtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacac agccgccctc agtgtctggg gccccagggc agagggtcac catctcctgc
      181 actgggagca gctccaacat tggaggttat tatatatcct ggtaccagca gctcccagga
      241 acggccccca aactcctcgt ctatgacaat aataagcgac cctcaggggt ttctgaccga
      301 ttctctggct ccaagtctgg ttcctcagcc accctgacca tcactgggct ccagactgag
      361 gatgaggctg attattactg ccagtcctat gacagcagtc tgagtgctcg ggtattcggc
      421 ggagggaccc ggctaaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01000485             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:24043:14026
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000485
VERSION     KCWK01000485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24043:14026"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66223.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           93 a          159 c          111 g          110 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtgga aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt gctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000486             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:6911:4990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000486
VERSION     KCWK01000486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:6911:4990"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..282
                     /note="immunoglobulin light chain variable region"
     V_region        4..282
     V_segment       4..243
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <210..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66224.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       245..282
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>320
                     /gene="IGLC"
BASE COUNT           68 a           91 c           82 g           79 t
ORIGIN      
        1 acatgggcag tggcatcagt gttggtaatt acaggatatt ctggtaccac cagaagccag
       61 ggagtcctcc ccggtatctt ctgaactacc acacagactc agatattcac cagggctctg
      121 gagtccccag ccgcttctct gggtccaagg atgcttcggc caatgcaggg attttactca
      181 tctctggact ccagtctgag gatgaggctg actattactg tatgatttgg cacaacaatg
      241 cttattgggt attcggcgga gggacccggc taaccgtcct aggtcagccc aaggctgccc
      301 cctcggtcac tctcttcccg
//
LOCUS       KCWK01000487             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:21075:15867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000487
VERSION     KCWK01000487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21075:15867"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66225.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       398..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           82 a          156 c          126 g          107 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcgctct cgggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcagtctgc cctgactcag
      121 cctccctcag tgtccaagtc tcttggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgacattg gtggttatga tggcgtctcc tggtaccagc agcactcagg gacagccccc
      241 agactcctga tttatgatgt cactaagcgg ccctcagggg tctcggatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctcacc atctctgggc tccagactga ggacgaggct
      361 gattattatt gttgctcata taggagtgga aacacttggc tattcggcgg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000488             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15210:13623
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000488
VERSION     KCWK01000488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15210:13623"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66226.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       401..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           96 a          154 c          111 g          115 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcatctcc tggagcatca gccagactca cctgcacctt gaacagtggc atcagtgttg
      181 ctaattacag gatattctgg taccaccaga agccagggag tcctccccgg tatcttctga
      241 actaccacac agactcagat attcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcagggattt tactcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtatg atttggcaca acaatgctta ttgggttttc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000489             450 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:24075:18747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000489
VERSION     KCWK01000489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24075:18747"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..412
                     /note="immunoglobulin light chain variable region"
     V_region        64..412
     V_segment       64..375
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66227.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       378..412
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>450
                     /gene="IGLC"
BASE COUNT           83 a          154 c          109 g          104 t
ORIGIN      
        1 acatgggtgg cctggactcc tctcctcctc ctgctcctct ctcactgcac aggttccctc
       61 tcccagcctg tgctgaccca gccaacctcc ctctcagcat ctccgggagc atcagccaga
      121 ctcaactgca ccttgagcag tggcgtcaat gtgggtagtt acagcatatt ctggtaccag
      181 cagaagccag ggagtcctcc ccggtacctt ctgtactacc agtcagactc aaggaagcac
      241 cagggctctg gagtccccag ccgcttctct ggatccaaag atgcttcagc caatgcaggg
      301 ctgttactga tctctgggct ccagtctgaa gatgaggctg actattactg tgccctatgg
      361 cacagcagcg cttcttgcat cttcggtggt gggacccggc tcaccgtcct aggtcagccc
      421 aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000490             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:12899:20196
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000490
VERSION     KCWK01000490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12899:20196"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..418
                     /note="immunoglobulin light chain variable region"
     V_region        101..418
     V_segment       101..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66228.1"
                     /translation="DYYCYSSDNNSKCIF"
     J_segment       390..418
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>460
                     /gene="IGLC"
BASE COUNT          101 a          139 c          121 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatagcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgaga tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttcccgca gaaggcaggc cagcccccta tggtgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttactcatca gacaacaata gtaaatgtat attcgacgga gggacccggc tgaccgtcgt
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000491             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:18569:17960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000491
VERSION     KCWK01000491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:18569:17960"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..426
                     /note="immunoglobulin light chain variable region"
     V_region        81..426
     V_segment       81..387
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66229.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           84 a          158 c          115 g          107 t
ORIGIN      
        1 acatgggggt agccgtgtcc accatggccc tgactcctct cctcctcctg ctcctctctc
       61 actgcacagg ttccctctcc cagcctgtgc tgactcagcc accctccctg tctgcatccc
      121 cgggagcatc ggccagactc ccctgcaccc tgagcagtga cctcagtgtt ggtagtaaaa
      181 acatgtactg gtaccagcag aagccaggga gcgctcccag gttattcctg tactactact
      241 ccgactcaga caagcagctg ggacctgggg tccccaatcg agtctctggc tccaaggaga
      301 cctcaagtaa cacagcgttt ttgctcatct ctgggctcca gcctgaggac gaggccgatt
      361 atttctgcca ggtgtttgac agtagtgttg tgttcttcgg aggagggacc cgactgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000492             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:9566:10965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000492
VERSION     KCWK01000492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9566:10965"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66230.1"
                     /translation="DYYCQTWDTGIVSF"
     J_segment       397..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           87 a          159 c          122 g          103 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgtactct gagcagtgga
      181 cacagcagct acaccatcgc atggcatcag caccagcaag ggaaggcccc tcggtatttg
      241 atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctga tcgcttctca
      301 ggctccagtt ccggggctga gcgctacctc accatctcca atttccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatact ggcattgtgt cattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000493             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:10759:16001
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000493
VERSION     KCWK01000493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10759:16001"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..421
                     /note="immunoglobulin light chain variable region"
     V_region        91..421
     V_segment       91..385
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66231.1"
                     /translation="DYYCCSYRTGNSWLF"
     J_segment       386..421
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           81 a          154 c          119 g          105 t
ORIGIN      
        1 acatgggggc agcgctctcg ggacgtctcc accatggcct gggctctgct cctcctcacc
       61 ctcctcactc agggcacagg atcctgggct cagtctgccc tgactcagcc tccctcagtg
      121 tccaagtctc ttggacagtc ggtcaccatc tcctgcactg gaaccagcag tgacattggt
      181 ggttatgatg gcgtctcctg gtaccaacag cactcaggga cagcccccag actcctgatt
      241 tatgatgtca ctaagcggcc ctcaggggtc tcggatcgct tctctggctc caagtctggc
      301 aacacggcct ccctcaccat ctctgggctc cagactgagg acgaggctga ttattattgt
      361 tgctcatata ggactggaaa cagttggcta ttcggcggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000494             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:20473:2953
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000494
VERSION     KCWK01000494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20473:2953"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66232.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       391..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           96 a          147 c          129 g           92 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gaactcctat gagctgactc
      121 agccaccctc agtgtcagcg gcctcaggac agacggccag gatcacctgt ggcggagaca
      181 acattggaat taaaaatgta cactggtacc accagaagcc accgcaggcc cctgtgctgg
      241 tcatctttgc tgataacaaa cggccctcag ggatccctga gcgattctct gcctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat gggtattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000495             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:23377:7490
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000495
VERSION     KCWK01000495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23377:7490"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66233.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          144 c          139 g           94 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccag cgcacgcccc tgtgctggtc
      241 atctatgcta atagcgaacg gtcctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg ggggtgaggc tgactattac
      361 tgtcaggtgt gggacatgcg tagtgatcaa ccgctattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000496             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15217:5079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000496
VERSION     KCWK01000496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15217:5079"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66234.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          140 c          133 g          102 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggtt ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggagga gacaacattg
      181 gaagtgaagt tgtcaactgg taccagcaga ggccaccgca ggcccctgtg ctggtcatct
      241 atgctgatta tgaacggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acacggccac cctgaccatc agcggagtcg aggccgggga tgaggctgac tattattgtc
      361 aggtgtggga catttatatt gaccatccgg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000497             380 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:23507:14224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000497
VERSION     KCWK01000497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 380)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23507:14224"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..342
                     /note="immunoglobulin light chain variable region"
     V_region        12..342
     V_segment       12..303
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <270..>314
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66235.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       312..342
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        343..>380
                     /gene="IGLC"
BASE COUNT           77 a          122 c           95 g           86 t
ORIGIN      
        1 acatgggggc ccagtctgtg ctgacgcagc cgccctcagt atctggggcc cccggacaga
       61 gggtcaccat ctcctgcatt agcagcagct ccaacatcgg ggcggcttat tatgtatcct
      121 ggtaccaaca gttcccagga acagccccca aactcctcat ctttgaaaat aataagcgac
      181 cctcaggggt ttctgaccga ttctctggct ccaagtctgg tccctcagcc tccctgacca
      241 tcactggact ccaatctgag gatgagggtg attattactg tttagcatgg gataccagcc
      301 tgaattggat cttcggcgga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      361 cctcggtcac tctcttcccg
//
LOCUS       KCWK01000498             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:14752:11292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000498
VERSION     KCWK01000498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14752:11292"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66236.1"
                     /translation="DYYCCSYRTGNSWLF"
     J_segment       398..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           83 a          156 c          125 g          107 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcgctct cgggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcagtctgc cctgactcag
      121 cctccctcag tgtccaagtc tcttggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgacattg gtggttatga tggcgtctcc tggtaccaac agcactcagg gacagccccc
      241 agactcctga tttatgatgt cactaagcgg ccctcagggg tctcggatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctcacc atctctgggc tccagactga ggacgaggct
      361 gattattatt gttgctcata taggactgga aacagttggc tattcggcgg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000499             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:16010:20679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000499
VERSION     KCWK01000499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16010:20679"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66237.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          155 c          121 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgcg ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000500             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:24209:11147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000500
VERSION     KCWK01000500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24209:11147"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..418
                     /note="immunoglobulin light chain variable region"
     V_region        101..418
     V_segment       101..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66238.1"
                     /translation="DYYCYSSDSNSKWLF"
     J_segment       390..418
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>460
                     /gene="IGLC"
BASE COUNT           99 a          141 c          122 g           98 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatagcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgaga tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatacttatt ggttcccgca gaaggcaggc cagcccccta tggtgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttactcatca gacagcaata gtaaatggct attcgacgga gggacccggc tgaccgtcgt
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000501             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:10246:7035
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000501
VERSION     KCWK01000501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10246:7035"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66239.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           86 a          156 c          130 g          111 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca ggtcccagga
      241 acagctccca aactcctcat ctattatagt gatcagcgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag
      361 gatgaggctg attattactg cgcggcatgg gatgatagtc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000502             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:17722:7759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000502
VERSION     KCWK01000502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17722:7759"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..400
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66240.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       403..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          160 c          118 g          107 t
ORIGIN      
        1 acatggggca gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccca gcctgtgctg acccagccaa cctccctctc
      121 agcatctccg ggagcatcag ccagactcaa ctgcaccttg agcagtggcg tcaatgtggg
      181 tagttacagc atattctggt accagcagaa gccagggagt cctccccggt accttctgta
      241 ctaccagtca gactcaagga agcaccaggg ctctggagtc cccagccgct tctctggatc
      301 caaagatgct tcagccaatg cagggctgtt actgatctct gggctccagt ctgaagatga
      361 ggctgactat tactgtgccc tatggcacag cagcgcttct tgcatcttcg gtggtgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000503             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:21104:11055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000503
VERSION     KCWK01000503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21104:11055"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66241.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           90 a          163 c          119 g          109 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt aataaaaaca tgtactggta ccaacagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactattccg actcagacaa gcagctggga cctggggtcc cccatcgagt
      301 ctctggctcc aaggagacct caactaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattact actgtcaggt gtatgacagt agtgctgtgt tattcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01000504             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:25761:12771
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000504
VERSION     KCWK01000504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:25761:12771"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66242.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       393..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT          105 a          137 c          122 g          101 t
ORIGIN      
        1 acatgggggg ctgtggttct aggaggaaga gctctgggtg tctcaccatc ctggaccact
       61 gttctgctcc cctttctcac tctctgcaca ggctctgagg cctcctatga gctgacacag
      121 ccaccctcag tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagaaata
      181 ctggcaaaaa aatatactca gtggttccag cagcagccag gccaggcccc tttcctggtg
      241 atatataaag acagtgagag gccctcaggg atccctgagc gattctctag ctccagttca
      301 gggacaacaa ttaccttgac catcagtggg gcccaggcag aagatgaggc tgactattac
      361 tgtcaatcag tagacagcag tggaaatctt ccgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000505             321 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:19663:14364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000505
VERSION     KCWK01000505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 321)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19663:14364"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..283
                     /note="immunoglobulin light chain variable region"
     V_region        8..283
     V_segment       8..244
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>255
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66243.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       246..283
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>321
                     /gene="IGLC"
BASE COUNT           65 a           97 c           80 g           79 t
ORIGIN      
        1 acatgggcca tctcctgcac tgggagcagc tccaacattg gaggttatta tgtgcagtgg
       61 taccagcagc ttccaggagc ggcccccaaa ctcctcatct atgaaaatga taaacgaccc
      121 tcaggggttt ctgatcgatt ctctggctcc cagtctgatt cctcagcctc cctgaccatc
      181 actggactcc agtctgagga tgaggctgat tattactgcc agtcctatga cagcagcttg
      241 agtgttgtgt tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      301 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000506             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:22003:9000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000506
VERSION     KCWK01000506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22003:9000"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66244.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000507             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:9167:13728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000507
VERSION     KCWK01000507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9167:13728"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66245.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          147 c          132 g           96 t
ORIGIN      
        1 acatgggggg gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000508             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:5649:7801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000508
VERSION     KCWK01000508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5649:7801"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..429
                     /note="immunoglobulin light chain variable region"
     V_region        107..429
     V_segment       107..397
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66246.1"
                     /translation="DYYCSSYAGSGVYIF"
     J_segment       400..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>474
                     /gene="IGLC"
BASE COUNT           79 a          152 c          126 g          117 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcatcctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg gcagtcggtc accatctcct gcattggaac
      181 cagcagtgat attgggtctt ataatgctgt gtcttggtac caacaacatc caggcaaagc
      241 ccccaaactc gtggtttttg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catatgcggg tagtggtgtt tacatcttcg gtgttgggac
      421 ccggctcacg tcctacgtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000509             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:28164:8847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000509
VERSION     KCWK01000509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:28164:8847"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66247.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          159 c          120 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacgcg cctcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000510             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:16577:20733
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000510
VERSION     KCWK01000510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16577:20733"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..262
                     /note="immunoglobulin light chain variable region"
     V_region        1..262
     V_segment       1..226
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>234
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66248.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       230..262
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        263..>300
                     /gene="IGLC"
BASE COUNT           67 a           84 c           89 g           60 t
ORIGIN      
        1 acatgggggg gagacaacat tggaactaaa actgtgcact ggtaccaaca gaagccaccg
       61 cagggccctg tattggtcat ctttgctgat agtagacggc cctcagggat ccctgagcga
      121 ttctctggct ccaattcagg gaacaccgcc accctgacca tcagcagggt cgaggccggg
      181 gatgaggctg actattactg tcaggtgtgg gacagtagta gtaaatggat attcggcggg
      241 gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000511             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:9710:9093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000511
VERSION     KCWK01000511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9710:9093"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..282
                     /note="immunoglobulin light chain variable region"
     V_region        8..282
     V_segment       8..247
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <210..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66249.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       249..282
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>320
                     /gene="IGLC"
BASE COUNT           65 a           97 c           80 g           78 t
ORIGIN      
        1 acatgggcat ctcctgcact ggaacgagca gtgatattgg ctattataac gctgtgtctt
       61 ggtaccaaca gcatccaggc aaagccccca aactcatcat ttttgacgtc attaagcggc
      121 cctcaggggt ctctgatcgc ttcgctgcct ccaagtctgg cgacacggcc tccctgacca
      181 tctctgggct ccgggctgag gatgaggctg attattactg cagctcatat gccggcagaa
      241 ataatttttt attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      301 cctcggtcac tctcttcccg
//
LOCUS       KCWK01000512             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:8197:10617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000512
VERSION     KCWK01000512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:8197:10617"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66250.1"
                     /translation="DYYCCSYRSGPTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          158 c          124 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttata atggcgtctc ctggtaccaa caacactcag ggacagcccc
      241 caaactcctg atttatgatc tgaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctgctcat ataggagtgg acccacttgg gttttcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000513             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:11007:10261
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000513
VERSION     KCWK01000513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11007:10261"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66251.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       403..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           84 a          162 c          127 g           98 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtggt gactcagtcg
      121 tcctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcggtggg
      181 cacagcgact acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggtatttg
      241 atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctga tcgcttctcc
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggagact ggcattcagg tgttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000514             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:11132:4738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000514
VERSION     KCWK01000514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11132:4738"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..441
                     /note="immunoglobulin light chain variable region"
     V_region        118..441
     V_segment       118..404
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66252.1"
                     /translation="DYHCQVWDLNSHHLLF"
     J_segment       406..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          150 c          141 g           98 t
ORIGIN      
        1 acatgggggg aacctgccca gcctgggcct caggaggcag cattgacggt gcctcagcca
       61 tggcctggac ttttctcctc ctcggcctcc ttgcttactg cacaggctct gcggccccct
      121 atgatctgac gcagccaccc tcgatttcag tgtccccagg acagacggcc aggctgacct
      181 gtgggggaga caacattgga agtgaagttg tgaactggta ccagcagaag ccaccgcagg
      241 cccctgtgtt ggtcatctat gctgacagcg agcggccctc agggatccct gagcgattct
      301 ctggctctaa atcagggaac acggccaccc tgaccatcag cggggtcgag gccggggatg
      361 aggctgacta tcactgtcag gtgtgggacc ttaatagtca tcatctgtta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000515             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:12787:8628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000515
VERSION     KCWK01000515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12787:8628"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..410
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66253.1"
                     /translation="DYYCGAWDSSLSGYIF"
     J_segment       412..449
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           94 a          160 c          123 g          110 t
ORIGIN      
        1 acatggggaa gctctgcctc agctgtgagc acagaaggca ggacttggga caatcttcat
       61 catgacctgg tcccctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtcctg acgcagccgc cctcagtgtc tgcggcccca gggcagaagg tcaccatctc
      181 ctgctctgga agtagctcca acatcgggag aaattctgtc tcctggtacc agcaggtccc
      241 aggaacggcc cccaaactcc tcacctatga caatgataag cgaccctcag gggtttctga
      301 ccgattctct ggctccaagt ctggttcctc agcctccctg gccatcactg gactccagac
      361 tggagatgag gctgattatt actgcggagc atgggatagc agtctgagtg gttacatttt
      421 cggtgctggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      481 gttcccg
//
LOCUS       KCWK01000516             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:23501:7949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000516
VERSION     KCWK01000516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:23501:7949"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..265
                     /note="immunoglobulin light chain variable region"
     V_region        1..265
     V_segment       1..227
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66254.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       229..265
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           66 a           91 c           85 g           61 t
ORIGIN      
        1 acatgggggg gagacaacat tggaagtcaa agtgtacact ggtaccagca caagccaccg
       61 caggcccctg ttctggtcat cttttattat accgaacggc cctcaggaat ccctgagcga
      121 ttctctggct ccaaatcagg gaacaccgcc accctgacca tcagcggggt cgaggccggg
      181 gatgaggctg actattactg tcaggtgtgg gacacaacta ttgatcacgg cttgttcgga
      241 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      301 ccg
//
LOCUS       KCWK01000517             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:16023:10571
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000517
VERSION     KCWK01000517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16023:10571"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66255.1"
                     /translation="DYYCQVWDSSSDHVFF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           91 a          147 c          137 g           93 t
ORIGIN      
        1 acatggggag cctgggcctc aggaagcagc cttggcggtg cctcagccat ggcctggacc
       61 cttctcctcc tcggcctcct cgctcactgc acaggctctg cggcctccta tgaaatgact
      121 cagccgcgct cagtgtctgt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aacattagaa gtaaaaatgt gaattggtac cagcagaagc caccgcaggc ccccgcgctg
      241 gtcatctatt atgatagcga ccggccctca gggatccctg agcgattctc tggctccaac
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtagtgat catgtgtttt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000518             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:10934:4991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000518
VERSION     KCWK01000518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10934:4991"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..439
                     /note="immunoglobulin light chain variable region"
     V_region        94..439
     V_segment       94..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66256.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       403..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           93 a          161 c          112 g          111 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcaatgtt
      181 ggtagttaca gcatattctg gtaccagcag aagccaggga gtcctccccg gtaccttctt
      241 tactactact cagactcaag taaccaccag gactctggag tccccagccg cttctctgga
      301 tcgaaagatg cttcagccaa tgcagggctt ttactgatct ctgggctcca gtctgaagat
      361 gaggctgact attactgtgc cacatggcac agcagcgctt cttacatctt cggtgctggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01000519             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:6803:3010
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000519
VERSION     KCWK01000519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:6803:3010"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66257.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          157 c          118 g          107 t
ORIGIN      
        1 acatgggggg gatctcacga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct atgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gctcctctgg
      301 ctccaagtcc ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcgggg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000520             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:5941:17820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000520
VERSION     KCWK01000520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:5941:17820"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66258.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          159 c          120 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacgag cctccggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000521             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:14995:5048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000521
VERSION     KCWK01000521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14995:5048"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..392
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66259.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       396..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           93 a          152 c          120 g          106 t
ORIGIN      
        1 acatgggggt gggtacagaa ggcaggactc aggacaatct ccagcatggc ctggttccct
       61 ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt gctgactcag
      121 cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc tggaagcagc
      181 tccaacatcg gaagtaataa tgtgtcctgg taccagcacc tcccaggaac agctcccaaa
      241 ctcctcatct attataatga tcaacgaggc tcaggtgtct ctgaccgatt ctctggctcc
      301 aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga tgaggctgat
      361 tattactgcg cagcgtggga tgatagcctg agtagttaca tcttcgctgc tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01000522             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:24885:8310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000522
VERSION     KCWK01000522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:24885:8310"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..411
                     /note="immunoglobulin light chain variable region"
     V_region        81..411
     V_segment       81..374
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66260.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       375..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           79 a          151 c          114 g          105 t
ORIGIN      
        1 acatggggag gacaatctcc agcatggcct ggttccctct cgtcctcacc ctcctcactc
       61 actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc tccctcagcg tctgaggccg
      121 ccaggaagag tgtctccatc tcctgttctg gaagcagctc caacatcgga agtcatagtg
      181 tctcctggta ccagcagctc ccaggcacag ctcccaaact cctcatctat tatagtgatc
      241 aacgagcctc aggtgtctct gaccgattct ctggctctca gtctggcacg tcagcctccc
      301 tggccatcag tgggctccag accgaggatg aggctgatta ttactgcgca gcttgggatg
      361 atagcctgag cggttacatc ttcggtgctg ggacccggct cgccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000523             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:24580:11320
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000523
VERSION     KCWK01000523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24580:11320"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..388
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66261.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       389..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           90 a          141 c          128 g           99 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagagctct ggggtgtctc caccatggcc tggactcctc
       61 tctggctcac cctcctcagt ctttgcacag gttctatggt ttcttctgag ctgactcagg
      121 accctgcagt gtctgtggcc ttgggggaga cagtcaggat tacctgccaa ggagacagcc
      181 tcagaagctc ttatgcaaac tggtaccaac agaggccagg ccaggcccct gtgctggtcg
      241 tctatggtaa caactaccgg ccctcaggga tcccagagcg attctctggc tcctactccc
      301 gaaacacagc ttccttgacc atcactgggg ctcaggtgga agatgaggct gactattact
      361 gtgactcctg ggacagcagc ggaacccaat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000524             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:14060:18030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000524
VERSION     KCWK01000524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14060:18030"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..260
                     /note="immunoglobulin light chain variable region"
     V_region        20..260
     V_segment       20..223
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <185..>232
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66262.1"
                     /translation="DYYCQSYDSNLSAMLF"
     J_segment       225..260
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>298
                     /gene="IGLC"
BASE COUNT           63 a           88 c           73 g           74 t
ORIGIN      
        1 acatgggaac ttcggggcgg gttattatgt gcactggtac cagcaacttc caggaacggc
       61 ccccaaactc ctcatctatg aaaacaatat gcgaccctca ggggtttctg atcgattctc
      121 tggctccaag tctggtacct cagcctccct gaccatcact ggactccagt ctgaggatga
      181 ggctgattat tactgccagt cctatgacag taatttgagt gctatgttat tcggaggagg
      241 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000525             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:16579:6435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000525
VERSION     KCWK01000525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16579:6435"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66263.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          149 c          136 g           95 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaac taaatatgtg cactggtacc agcagaagcc agcgcaggcc cctgtgttgg
      241 tcatctatgc tgataccaga cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gtgtcgaggc cgggtatgag gctgactatt
      361 tctgtcaggt gtgggacgat agtagtgatc atccggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000526             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:23064:17445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000526
VERSION     KCWK01000526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23064:17445"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..438
                     /note="immunoglobulin light chain variable region"
     V_region        95..438
     V_segment       95..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66264.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          162 c          112 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccctgcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcggccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 ccttctactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000527             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:16902:11365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000527
VERSION     KCWK01000527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16902:11365"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..403
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66265.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       407..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          155 c          122 g          110 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc actctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata atgtgtcctg gtaccagcac ctcccaggaa
      241 cagctcccaa actcctcatc tattataatg atcaacgagg ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcgtggg atgatagcct gagtagttac atcttcgctg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01000528             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:13804:6097
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000528
VERSION     KCWK01000528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13804:6097"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66266.1"
                     /translation="DYYCQTWDTGIVLF"
     J_segment       397..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           90 a          161 c          121 g           99 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agactgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaaactca cctgcactct gaacagtgga
      181 cacagcagct acaccatcgc gtggcatcag cagcagcaag ggaaggcccc ccggtacttg
      241 atgtggctta aaactgatgg cagccatagc aagggggacg ggatccctga tcgcatctca
      301 ggctccagtt ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatact ggcattgtgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000529             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:13922:10937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000529
VERSION     KCWK01000529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13922:10937"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66267.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          146 c          131 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000530             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:9018:23972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000530
VERSION     KCWK01000530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9018:23972"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..418
                     /note="immunoglobulin light chain variable region"
     V_region        102..418
     V_segment       102..388
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66268.1"
                     /translation="DYSCDSWDSSGTQF"
     J_segment       389..418
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>458
                     /gene="IGLC"
BASE COUNT           88 a          142 c          128 g          100 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagagctct ggggtgtctc caccatggcc tggactcctc
       61 tctggctcac cctcctcagt ctttgcacag gttctatggt ttcttctgag ctgactcagg
      121 accctgcagt gtctgtggcc ttgggacaga cagtcaggat tacctgccaa ggagacagcc
      181 tcagaagctc ttatgcaagc tggtaccaac agaggccagg ccaggcccct gtgctggtcg
      241 tctatggtaa caactaccgg ccctcaggga tcccagagcg attctctggc tcctactcac
      301 gaaacacagc ttccttgacc atctctgggg ctcaggtgga agatgaggct gactattcct
      361 gtgactcctg ggacagcagc ggaacccaat tcggaggagg gacccggctg accgtcctgg
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000531             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:20660:8416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000531
VERSION     KCWK01000531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20660:8416"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66269.1"
                     /translation="DYYCQSYDSSLSGVLF"
     J_segment       415..449
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           94 a          155 c          125 g          113 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc ggacagaggg tcaccatctc
      181 ctgcagtggg agcaactcca acattggata ctattatgtg cagtggtacc agcagcttcc
      241 aggaacggcc cccaaactcc tcatctatga aaataataaa cgaccctctg gggtttctga
      301 tcgattctct ggctcccagt ctggtacctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agtttgagtg gtgtcttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01000532             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14319:19926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000532
VERSION     KCWK01000532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14319:19926"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66270.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          145 c          131 g           98 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctttga gttgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaatta aatttgtcca ctggtaccag cagaagccag cgcaggcccc tgtgaaggtc
      241 atctatgctg atgacaaacg gccctcaggg atccctgaga gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgattattcc
      361 tgtcaggtgt gggacagtga gactgattat tacatcttcg gtactgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000533             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:19703:6468
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000533
VERSION     KCWK01000533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19703:6468"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66271.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          145 c          138 g           93 t
ORIGIN      
        1 acatgggctg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttggaagtga agttgtgaac tggtaccagc agaagccagc gcacgcccct gtgctggtca
      241 tctatgctaa tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg gggtgaggct gactattact
      361 gtcaggtgtg ggacatgcgt agtgatcaac cgctattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000534             332 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:6120:17753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000534
VERSION     KCWK01000534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 332)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6120:17753"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..294
                     /note="immunoglobulin light chain variable region"
     V_region        8..294
     V_segment       8..254
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>266
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66272.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       258..294
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>332
                     /gene="IGLC"
BASE COUNT           71 a           94 c           99 g           68 t
ORIGIN      
        1 acatgggagg acagacggcc aggatcacct gtgggggaga caacattgga agtgaagttg
       61 tcaactggta ccaacagaag ccaccgcagg cccctgtggt ggtcatctat gctgattatg
      121 aacggccctc agggatccct gaccgattct ctggctccaa atcagggaac acggccaccc
      181 tgaccatcag cggagtcgcg gccggggatg aggctgacta ttactgtcag gtttgggaca
      241 tttatactga tcatccggtg ttgttcggag gagggacccg gctgaccgtc ctaggtcagc
      301 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000535             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:6373:3739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000535
VERSION     KCWK01000535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6373:3739"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..396
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66273.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       397..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           90 a          152 c          119 g          110 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactt cacagttcca gggtcctggg cccagtctgt gctgacgcag
      121 ccgccctcag tgtctggggc gcccgggcag agggtcacca tctcctgcac tgggagcagc
      181 tccaacattg gagattattt tgtgcagtgg taccagcacc ttccaggaac ggcccccaaa
      241 ctcctcatct atgaaaataa taagcggccc tcagggattt ctgatcgatt ctctggctcc
      301 cagtctggaa cctcagcctc cctgaccatc actggactcc agtctgagga tgaggctgat
      361 tattactgcc agtcctatga cagcagtttg attgctgtgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000536             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:17460:16626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000536
VERSION     KCWK01000536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17460:16626"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..418
                     /note="immunoglobulin light chain variable region"
     V_region        94..418
     V_segment       94..379
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <343..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66274.1"
                     /translation="DYYCDSRDNSGTLPVF"
     J_segment       384..418
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>456
                     /gene="IGLC"
BASE COUNT           91 a          142 c          125 g           98 t
ORIGIN      
        1 acatggggag aagcagagct ctggggtgtc tccaccatgg cctggactcc tctctggctc
       61 accctcctca gtctttgcac aggttctgtg gtttcttctg agctgactca ggaccctgca
      121 gtgtctgtgg ccttgggaca gacagtcagg atcacctgcc aaggagacag cctcagaagc
      181 tattatgcaa gctggtacca acagaagcca ggccaggccc ctgtgctggt cgtctatggt
      241 aacaactacc ggccctcagg gatcccagag cgattctctg gctccagctc aagaaacaca
      301 gcttccttga ccatcactgg ggctcaggtg gaagatgagg ctgactatta ctgtgactcc
      361 cgggacaaca gcggtaccct tccggtattc ggcggaggga cccggctgac cgtcctaggt
      421 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000537             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:14319:11693
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000537
VERSION     KCWK01000537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:14319:11693"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..397
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66275.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       402..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           88 a          153 c          119 g          110 t
ORIGIN      
        1 acatggggga tctcaggagg cagcgctctc aggacttctc caccatggtc tgggctctgc
       61 tcctcctcac cctcctcact cagggcacag gatcctgggc tcaggctgcc ccgactcaga
      121 ctccctctgt gtccgggtct cctggacagt cggtcaccat ctcctgcact ggaaccagca
      181 gtgatattgg gtattattat gctgtgtctt ggtaccagca tcatccaggc aaagccccca
      241 agctcatgat ttatgaggtc aataaacggc ccgcaggggt ctctgatcgc ttctctggct
      301 ccaagtctgg caacacggcc tccctgacca tctctgggct ccagactgag gatgaggctg
      361 attattactg cagctcatat gcaggcagca acactttatt cttcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000538             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:18044:5065
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000538
VERSION     KCWK01000538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18044:5065"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66276.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       394..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          147 c          121 g          107 t
ORIGIN      
        1 acatggggag ctgtgggctc agaagcagaa ctctgggtcc tctccaccat ggcctggacc
       61 cctcccctgc tcatcctcct cactctctgc acaggttccg tggtttcctc tgagctgact
      121 caggagcctg cattgtctgt ggccttggga catacagtca ggatgacctg ccaaggagac
      181 agcctcaaaa cctattatgc aagctggtac cagcagaagc caggccaggt ccctgtgctg
      241 gtcatctatg gtaacaacta ccggccctca gggatcccag gccgattctc tgtctcctgg
      301 tcaggaaaca caggttcctt gaccatcact gcggctcagg tggaagatga ggctgactat
      361 tattgtaagt cctgggacag cagtggtacc cattacatct tcggtgctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01000539             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:7720:3163
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000539
VERSION     KCWK01000539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7720:3163"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66277.1"
                     /translation="DYYCAAWDDSLTGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          153 c          116 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccgg gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta atagtgtatc ctggtatcaa caactcccag aaacggctcc caaactcctc
      241 atgtattata gtcatcggcg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacttcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgaccggt tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000540             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:9045:8528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000540
VERSION     KCWK01000540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:9045:8528"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66278.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>465
                     /gene="IGLC"
BASE COUNT           91 a          148 c          130 g           96 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtccaaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000541             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:10178:2008
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000541
VERSION     KCWK01000541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10178:2008"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66279.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          162 c          124 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagcgggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000542             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:9528:5653
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000542
VERSION     KCWK01000542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:9528:5653"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..420
                     /note="immunoglobulin light chain variable region"
     V_region        90..420
     V_segment       90..381
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66280.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       390..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           89 a          150 c          115 g          104 t
ORIGIN      
        1 acatggggga ggcagcactc aggacagtct ccagcatggc ctggtctctc cttctcactc
       61 tgctggttca ctgcacaggg tcctgggccc agtctgtgct gacgcagccg ccctcagcat
      121 ctggggcccc cggacagagg gtcaccatct cctgcattag cagcagctcc aacatcgggg
      181 cggcttatta tgtatcctgg taccaacagt tcccaggaac agcccccaaa ctcctcatct
      241 ttgaaaataa taagcgaccc tcaggggttt ctgaccgatt ctctggctcc aagtctggtc
      301 cctcagcctc cctgaccatc actggactcc aatctgagga tgaggctgat tattactgtt
      361 tagcatggga taccagcctg aattggatct tcggcggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000543             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:20654:10900
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000543
VERSION     KCWK01000543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20654:10900"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66281.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          152 c          122 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttcgctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000544             299 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:23475:5677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000544
VERSION     KCWK01000544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 299)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23475:5677"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    70..261
                     /note="immunoglobulin light chain variable region"
     V_region        70..261
     V_segment       70..224
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>233
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66282.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       225..261
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        262..>299
                     /gene="IGLC"
BASE COUNT           62 a          106 c           65 g           66 t
ORIGIN      
        1 acatgggctc tcccaacctg tgctgaccca gccaacctcc ctctcagcat ctccgggaac
       61 atcagccaga ctcagactca agtaaccacc aggactctgg agtccccagc cgcttctctg
      121 gatcgaaaga tgcttcagcc aatgcagggc ttttactgat ctctcggctc cagtctaaag
      181 atgaggctga ctattactgt gccacatggc acagcagcgc ttcttacatc ttcggtcctg
      241 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000545             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:13297:18315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000545
VERSION     KCWK01000545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13297:18315"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66283.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          106 a          136 c          122 g           99 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatactcagt ggttccagca gcagccaggc caggcccctt tcctggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacaatg accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagta gacagcagtg gaaatcttcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000546             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:14724:13967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000546
VERSION     KCWK01000546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:14724:13967"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..278
                     /note="immunoglobulin light chain variable region"
     V_region        7..278
     V_segment       7..242
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <206..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66284.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       246..278
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>316
                     /gene="IGLC"
BASE COUNT           70 a           90 c           94 g           62 t
ORIGIN      
        1 acatggggcc aggatcacct gtgggggaga caacattgga actaaaactg tgcactggta
       61 ccaacagaag ccaccgcagg gccctgtatt ggtcatcttt gctgatagta gacggccctc
      121 agggatccct gagcgattct ctggctccaa ctcagggaac accgccaccc tgaccatcag
      181 cagggtcgag gccggggatg aggctgacta ttactgtcag gtgtgggaca gtagtagtaa
      241 atggatattc ggcgggggga cccggctaac cgtcctaggt cagcccaagg ctgccccctc
      301 ggtcactctc ttcccg
//
LOCUS       KCWK01000547             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:14570:11615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000547
VERSION     KCWK01000547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:14570:11615"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..425
                     /note="immunoglobulin light chain variable region"
     V_region        80..425
     V_segment       80..388
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66285.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          158 c          111 g          106 t
ORIGIN      
        1 acatggggta gccgtgtcca ccatggccct gactcctctc ctcctcctgc tcctctctca
       61 ctgcacaggt tccctctccc agcctgtgct gactcagcca ccctccctgt ctgcatcccc
      121 gggagcatcg gccagactcc cctgcaccct gagcagtgac ctcagtgttg gtaataaaaa
      181 catgtactgg taccaacaga agccagggag cgctcccagg ttattcctgt actactactc
      241 cgactcagac aagcagctgg gacctggggt ccccaatcga gtctctggct ccaaggagac
      301 ctcaactaac acagcgtttt tgctcatctc tgggctccag cctgaggacg aggccgatta
      361 ttactgtcag gtgtttgaca gtagtgctgt gttattcgga ggagggaccc gactgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000548             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:23513:2058
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000548
VERSION     KCWK01000548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:23513:2058"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66286.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       377..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>449
                     /gene="IGLC"
BASE COUNT           87 a          140 c          128 g           94 t
ORIGIN      
        1 acatggggag cattgacggt gcctcagcca tggcctggac ttttctcctc ctcggcctcc
       61 ttgcttactg cacagactct gcggcctcct atgatctgac tcagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gtgggggaga caacattgga ggtgaagttg
      181 tgaactggta ccagcagaag ccaccgcagg cccctgtcct ggtcatctat gctaataacg
      241 aacggccctc agggatccct gagcgattct ctggctccaa atcagggaac acggccaccc
      301 tgaccatcag cggggtcgag gccggggatg aggctgacta ttactgtcag gtgtggggcg
      361 ttactagtga tcatccctta ttcggaggag ggacccggct gaccgtccaa ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000549             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:19441:11945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000549
VERSION     KCWK01000549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19441:11945"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66287.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          156 c          118 g          111 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggaacatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgtctacca cgtacactgg taccaacaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggggt ccccagccgc ttctctggat
      301 ccagtaatgc ttcagcgaac acagggattt tacgcatttc tgggatccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtct ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000550             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:21947:4877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000550
VERSION     KCWK01000550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21947:4877"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..267
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66288.1"
                     /translation="VYYCAIGHSSGLYIF"
     J_segment       269..306
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           68 a          105 c           91 g           80 t
ORIGIN      
        1 acatgggagc cagtctcaca tgcaccttca gcggtggcat caatgttgct gtctaccacg
       61 tacactggta ccagcagaag ccagggagtc ccccccggta tcttctgagg tacaaatcag
      121 actcagataa gggccagggc tctggggtcc ccagccgctt ctctggatcc agtaatgctt
      181 cagcgaacac agggatttta cgcatttctg ggctccagtc tgaggatgag gctgtctatt
      241 actgtgccat tgggcacagc agcggtcttt acatcttcgg tgctgggacc cggctcaccg
      301 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000551             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18269:7170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000551
VERSION     KCWK01000551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18269:7170"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66289.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          159 c          112 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tggactccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000552             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:8075:8997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000552
VERSION     KCWK01000552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8075:8997"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66290.1"
                     /translation="DYYCQVWDIYTDHPVIF"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          142 c          136 g          100 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag cctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtcaac tggtaccagc agaagccacc gcaggcccct gtggtggtca
      241 tctatgctga ttatgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcggag tcgaggccgg ggatgaggct gactattact
      361 gtcaggtttg ggacatttat actgatcatc cggtgatatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000553             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:5566:18565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000553
VERSION     KCWK01000553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5566:18565"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..254
                     /note="immunoglobulin light chain variable region"
     V_region        11..254
     V_segment       11..217
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66291.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       220..254
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           58 a           84 c           88 g           62 t
ORIGIN      
        1 acatgggatc ggaggtgaag ttgtgaattg gtaccagcag aagccaccgc aggcccctgt
       61 gttggtcatc tatgctgata gcgagcggcc ctcagggatc cctgagcgat tctctggctc
      121 caaatcaggg aacgcggcca ccctgaccat cagcggggtc gaggccggag atgaggctga
      181 ctattactgt caggtgtggg accttaatag tcatcatctc ttattcggag gagggacccg
      241 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000554             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:21128:4379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000554
VERSION     KCWK01000554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21128:4379"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..421
                     /note="immunoglobulin light chain variable region"
     V_region        103..421
     V_segment       103..389
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66292.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       390..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>457
                     /gene="IGLC"
BASE COUNT           90 a          140 c          128 g           99 t
ORIGIN      
        1 acatgggggg tgggctcaga agcagagctc tggggtgtct ccaccatggc ctggactcct
       61 ctctggctca ccctcctcag tctttgcaca ggttctatgg tttcttctga gctgactcag
      121 gaccctgcag tgtctgtggc cttggggcag acagtcagga ttacctgcca aggagacagc
      181 ctcagaagct cttatgcaaa ctggtaccaa cagaggccag gccaggcccc tgtgctggtc
      241 gtctatggta acaactaccg gccctcaggg atcccagagc gattctctgg ctcctactcc
      301 cgaaacacag cttccttgac catcactggg gctcaggtgg aagatgaggc tgactattac
      361 tgtgactcct gggacagcag cggaacccaa ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcg
//
LOCUS       KCWK01000555             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:11941:18876
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000555
VERSION     KCWK01000555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11941:18876"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..263
                     /note="immunoglobulin light chain variable region"
     V_region        1..263
     V_segment       1..225
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66293.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       231..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           62 a           85 c           97 g           57 t
ORIGIN      
        1 atggggggga gacaagattg gaagtgaagt tgtgaactgg taccagcaga agccagcgca
       61 ggcccctgtg ctggtcatct atgctgatag cgaacggccc tcagggatcc ctgagcgatt
      121 ctctggctcc aaatcaggga acacggccac cctgaccatc agcggggtcg aggccggggg
      181 tgaggctgac tattactgtc aggtgtggga catgcgtagt gatcaaccgc tattcggcgg
      241 agggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01000556             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:6607:11341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000556
VERSION     KCWK01000556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6607:11341"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..424
                     /note="immunoglobulin light chain variable region"
     V_region        101..424
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66294.1"
                     /translation="DYHCQVWDINSHHLLF"
     J_segment       390..424
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>463
                     /gene="IGLC"
BASE COUNT           89 a          142 c          135 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagt ctctgcggcc tcctatgatc tgacgcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccaggctg acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgac agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgaaca tcagcggggt cgaggccggg gatgaggctg actatcactg
      361 tcaggtgtgg gacattaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctacgtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000557             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:20217:6602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000557
VERSION     KCWK01000557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:20217:6602"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66295.1"
                     /translation="AYYCQVWDSDSDHYIF"
     J_segment       392..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           92 a          149 c          131 g           95 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaac taattttgtg cactggtacc agcagaagcc agcgcaggcc cctatgcagg
      241 tcatctatgc tgatagcaaa cggccctcag ggatccctga gagattctct ggctccaact
      301 caggaaacac cgccaccctg accatcagcg gagtcgaggc cggggatgag gctgcctatt
      361 actgtcaggt gtgggacagt gatagtgatc attacatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01000558             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:12167:18432
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000558
VERSION     KCWK01000558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12167:18432"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66296.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          163 c          123 g          109 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 tcattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaactaac acagcgtttt tgctcatctc tggactccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctaa tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01000559             310 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:22824:11885
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000559
VERSION     KCWK01000559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 310)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22824:11885"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..272
                     /note="immunoglobulin light chain variable region"
     V_region        8..272
     V_segment       8..235
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <197..>244
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66297.1"
                     /translation="DYYCCSHGGSNIFVLF"
     J_segment       242..272
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        273..>310
                     /gene="IGLC"
BASE COUNT           62 a           96 c           81 g           71 t
ORIGIN      
        1 acatggggga accagcagtg acatcggcgg ttataactat gtctcctggt accaacagca
       61 tccagacaca gcccccaaac tcatgattta tgaggtcact aagcggccct caggggtctc
      121 tgatcgcttc tctggctcca agtctggcaa cacggcctcc ctgaccatct ctgggctccg
      181 ggctgaggac gaggctgatt attactgctg ctcacatgga ggcagtaata ttttcgtctt
      241 gttcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac
      301 tctcttcccg
//
LOCUS       KCWK01000560             345 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:15278:20623
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000560
VERSION     KCWK01000560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 345)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15278:20623"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..307
                     /note="immunoglobulin light chain variable region"
     V_region        8..307
     V_segment       8..268
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <235..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66298.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       270..307
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>345
                     /gene="IGLC"
BASE COUNT           69 a          106 c           91 g           79 t
ORIGIN      
        1 acatgggctg gggcccccgg gcagagggtc accatctcct gcactgggag cagctccaac
       61 atcggggcgg gtttttatgt atcctggtac cagcagttcc caggaaaagc ccccaagctc
      121 ctcatctttg aaaataacaa gcgaccctca ggggtttctg accgattctc tggctccaag
      181 tctggttcct cagcctccct gaccatcact ggactccaat ctgaggatga ggctgattat
      241 tattgttcat catgggaaag cagcctgaat tgggtattcg gcggagggac ccggctgacc
      301 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000561             365 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:13709:15885
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000561
VERSION     KCWK01000561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 365)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 365)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13709:15885"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..327
                     /note="immunoglobulin light chain variable region"
     V_region        125..327
     V_segment       125..290
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <255..>299
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66299.1"
                     /translation="DYYCQVYDSTANVLF"
     J_segment       291..327
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        328..>365
                     /gene="IGLC"
BASE COUNT           63 a          126 c           91 g           85 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctggt cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgta ctactactcc gactcagaca agcagctggg acctggggtc cccactcgag
      181 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggactccagc
      241 ccgaggacga ggccgattat tactgtcagg tgtatgacag tactgctaat gtgttattcg
      301 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      361 tcccg
//
LOCUS       KCWK01000562             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:19275:8417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000562
VERSION     KCWK01000562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19275:8417"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..250
                     /note="immunoglobulin light chain variable region"
     V_region        8..250
     V_segment       8..213
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66300.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       215..250
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        251..>289
                     /gene="IGLC"
BASE COUNT           62 a           88 c           80 g           59 t
ORIGIN      
        1 acatggggga agtcaaagtg tgcactggta ccagcacaag ccaccgcagg cccctgttct
       61 ggtcatcttt tattataccg aacggccctc aggaatccct gagcgaatct ctggctccaa
      121 atcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      181 ttactgtcag gtgtgggaca caagtcttga tcacggctta tttggaggag ggacccggct
      241 gaccgtccta agtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000563             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:14610:6758
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000563
VERSION     KCWK01000563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14610:6758"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..252
                     /note="immunoglobulin light chain variable region"
     V_region        5..252
     V_segment       5..209
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <174..>224
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66301.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       215..252
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        253..>290
                     /gene="IGLC"
BASE COUNT           65 a           89 c           63 g           73 t
ORIGIN      
        1 acatgggggg ttattatgta tcctggtacc agcagttccc aggaacagcc cccaaactcc
       61 tcatctatga aaataataaa cgaccctcag gggtttctga ccgattctct ggctccaagt
      121 ctggtacctc agcctccctg accatcactg gactccaatc tgaggatgag gctgattatt
      181 actgctcagc atgggatagc agcctgagta tcaattacat cttcggttct gggacccgtc
      241 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000564             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:21990:11051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000564
VERSION     KCWK01000564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:21990:11051"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66302.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          154 c          118 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctcttgg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000565             379 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:20138:9398
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000565
VERSION     KCWK01000565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 379)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 379)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..379
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20138:9398"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..341
                     /note="immunoglobulin light chain variable region"
     V_region        8..341
     V_segment       8..302
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <269..>313
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66303.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       304..341
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        342..>379
                     /gene="IGLC"
BASE COUNT           77 a          120 c           96 g           86 t
ORIGIN      
        1 acatgggcag ccggcctccc tctcagcatc tcctggagca tcagccagtc tcacatgcac
       61 cttcagcggt ggcatcaatg ttgctgtcta ccacatacac tggtaccagc agaagccagg
      121 gagtcccccc cggtatcttc tgaggtacaa atcagactca gataagggcc agggctctgg
      181 agtccccagc cgcttctctg gatccagtaa tgcttcagcg aacacaggga ttttacgcat
      241 ttctgggctc cagtctgagg atgaggctga ctattactgt gccattggac acagcagcgg
      301 tctttacatc ttcggtgctg ggacccggct cagcgtccta ggtcagccca aggcttcccc
      361 cacggtcact ctgttcccg
//
LOCUS       KCWK01000566             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:14748:2207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000566
VERSION     KCWK01000566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14748:2207"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..385
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66304.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       386..421
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           98 a          141 c          130 g           90 t
ORIGIN      
        1 acatgggggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg gacccttctc
       61 ctcctcggcc tcctcgctta ctgcacaggc tctgcgacct cctatgagct gactcaggca
      121 ccctcagtgt cagcggcctc aggacagacg gccaggatca cctgtggcgg agacaacatt
      181 ggaattaaaa atgtccactg gtaccagcag aagccagcac aggcccctgt ggtagtcatc
      241 tatgctgata acaaacggcc ctcagggatc cctgagcgac tctctggctc caactcaggg
      301 aatattgcca ccctgaccat cagcagggtc gaggccgggg atgaggcaga ctattactgt
      361 caggtgtggg acagtagtag taaatgggta ttcggcggag ggacccggct aaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000567             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:24242:9903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000567
VERSION     KCWK01000567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24242:9903"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66305.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          149 c          116 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgccaaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000568             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:22777:19083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000568
VERSION     KCWK01000568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22777:19083"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66306.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       394..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           93 a          152 c          119 g          105 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtcaccatc tcctgttctg gaagcagctc
      181 caacatcgga agtaataatg tgtcctggta ccagcacctc ccaggaacag ctcccaaact
      241 cctcatctat tataatgatc aacgaggctc aggtgtctct gaccgattct ctggctccaa
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcgtgggatg atagcctgag tagttacatc ttcgctgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000569             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:9461:14074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000569
VERSION     KCWK01000569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:9461:14074"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66307.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          161 c          119 g          107 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca actgcacctt gagcagtggc gtcaatgtgg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctgt
      241 actaccagtc agactcaagg aagcaccagg gctctggcgt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggctgt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc ctatggcaca gcagcgcttc ttgcatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000570             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:22768:15915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000570
VERSION     KCWK01000570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22768:15915"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..273
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <239..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66308.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       277..314
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           74 a          109 c           89 g           80 t
ORIGIN      
        1 acatgggtca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt ctggaagcag
       61 ctccaacatc ggaagtaata atgtgtcctg gtaccagcac ctcccaggaa cagctcccaa
      121 actcctcatc tattataatg atcaacgagg ctcaggtgtc tctgaccgat tctctggctc
      181 caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg atgaggctga
      241 ttattactgc gcagcgtggg atgatagcct gagtagttac atcttcgctg ctgggacccg
      301 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01000571             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14801:15721
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000571
VERSION     KCWK01000571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14801:15721"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..406
                     /note="immunoglobulin light chain variable region"
     V_region        88..406
     V_segment       88..374
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66309.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       375..406
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           91 a          136 c          119 g           98 t
ORIGIN      
        1 tcagaagcag agctctgggg tgtctccacc atggcctgga ctcctctctg gctcaccctc
       61 ctcagtcttt gcacaggttc tgtggtttct tctgagctga ctcaggaccc tgcagtgtct
      121 gtggccttgg gacagacagt caggatcacc tgccaaggag acagcctcag aagttattat
      181 gcaagttggt accagcagaa gccaggccag gcccctatac tggtcgtcta tggtaacaat
      241 taccggccct cagggatccc agagcgattc tctggctcca gtacacgaaa cacagcttcc
      301 ttgaccatca ctggggctca ggtggaagat gaggctgact attactgtga ctcctgggac
      361 agccgcggaa cccaattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct
      421 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000572             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14430:17935
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000572
VERSION     KCWK01000572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14430:17935"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66310.1"
                     /translation="DYYCSSYAGRNTHWLF"
     J_segment       410..440
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           88 a          162 c          119 g          109 t
ORIGIN      
        1 acatgggggc tggggtctca gcaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caactacacc caggcaaagc
      241 ccccaaactc atgatttatg atgtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctgacaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 gactgattat tactgcagct catatgcagg ccgcaacact cattggcttt tcggcggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000573             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:13782:18415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000573
VERSION     KCWK01000573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13782:18415"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66311.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       417..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           93 a          158 c          124 g          110 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg acagagggtc accatctcct
      181 gcattagcag cagctccaac atcggggcgg cttattatgt atcctggtac caacagttcc
      241 caggaacagc ccccaaactc ctcatctttg aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtccct ccgcctccct gaccatcact ggactccaat
      361 ctgaggatga ggctgattat tactgtttag catgggatac cagcctgaat tggatcttcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000574             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:16130:9542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000574
VERSION     KCWK01000574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16130:9542"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66312.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       408..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          158 c          117 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatatac tggtaccgcc agaagccagc gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg cgattatatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000575             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:16220:15081
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000575
VERSION     KCWK01000575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16220:15081"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..402
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66313.1"
                     /translation="DYYCAAWDDSLRSYIF"
     J_segment       406..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          155 c          124 g          107 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaataa tgtgtcctgg taccagcacc tcccaggaac
      241 agctcccaaa ctcctcatct actataatga tcaacgaggc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcgtggga tgatagcctg aggagttaca tcttcgctgc
      421 tgggacccgg gtcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01000576             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:24945:4721
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000576
VERSION     KCWK01000576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24945:4721"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66314.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           92 a          144 c          133 g           92 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctcttcgac ctcctatgaa ctgactcagt
      121 caccctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa aactgtgcac tggtaccagc agaagccacc gcagggccct gtattggtca
      241 tctttgctga cagtaaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000577             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:23845:19009
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000577
VERSION     KCWK01000577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:23845:19009"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..303
                     /note="immunoglobulin light chain variable region"
     V_region        87..303
     V_segment       87..266
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66315.1"
                     /translation="DYYYYSADSSGNWVF"
     J_segment       267..303
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           67 a           99 c           95 g           80 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatagcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagc tgaagccagg ccagtcccct gtgatggtca
      121 tctttgagga cagcaaacgg ccctctggga tccctgagag attctttggc tccagtttag
      181 ggacagtggc caccttgact ataattgggg cccaggtgga ggatgaagat gactactact
      241 attactcagc agacagtagt ggtaattggg tattcgccgg agggacccgg ctgaccgtcc
      301 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000578             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:4409:20001
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000578
VERSION     KCWK01000578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4409:20001"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66316.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       392..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           85 a          149 c          139 g           91 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag gctctgcgac ctcctatgag ctggctcagc
      121 caccctcggt gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa ctatgtgcac tggtaccagc agaagccagc gcaggcccct gtcgagatca
      241 tctttgctga taacaaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggatcaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactatttct
      361 gtcaggtgtg gggcagtcgt agtgatcatc cggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000579             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:17283:11897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000579
VERSION     KCWK01000579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17283:11897"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..424
                     /note="immunoglobulin light chain variable region"
     V_region        101..424
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66317.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttatttgga ggagggaccc ggctgaccgt
      421 cctaagtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000580             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:24961:9027
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000580
VERSION     KCWK01000580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:24961:9027"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66318.1"
                     /translation="DYYCQSYDSSLSGVLF"
     J_segment       414..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          155 c          127 g          114 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct gggtcgcccg ggcagagggt caccatctcc
      181 tgcagtggga gcaactccaa cattggatac tattatgtgc agtggtacca gcagcttcca
      241 gggacggccc ccaaactcct catctatgaa aataataagc gaccctctgg ggtttctgat
      301 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtttgagtgg tgtcttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01000581             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:20139:2687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000581
VERSION     KCWK01000581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20139:2687"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66319.1"
                     /translation="DYYCTAWDNSLSSPIF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          153 c          113 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaaata attatgtata ctggtaccaa cagttcccag gaatggcccc caaactcctc
      241 atctattata gtcgtcagcg accctcaggg gtccctgacc gattctctgc ctctaaatct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtacagcat gggataacag cctgagcagt ccgatattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000582             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:17581:18764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000582
VERSION     KCWK01000582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17581:18764"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66320.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          107 a          136 c          120 g          100 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatactcagt ggttccagca gcagccaggc caggcccctt tcctggtaat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacaatt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagta gacagcagtg gaaatcttcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000583             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:21510:10485
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000583
VERSION     KCWK01000583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21510:10485"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66321.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           92 a          143 c          131 g           96 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca gtctctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag cctgccagga tcacctgtgg gggagacaac
      181 attggaatta aaactgtgca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtaaacg gccctcgggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000584             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:11292:4218
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000584
VERSION     KCWK01000584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:11292:4218"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66322.1"
                     /translation="DYYCCSRSTSSTYVF"
     J_segment       399..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           82 a          161 c          116 g          113 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacgtt ggtggttata actctgtctc ctggtaccaa caacacccag gcaaagcccc
      241 caaagtcatg atttttggtg tcaataatcg gccctctggg gtctctgacc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagtctg aggacgaggc
      361 tgattattac tgttgttcac gttcaaccag tagcacttac gtcttcggtc ctgggacccg
      421 gctcaccgtc ctgggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01000585             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:19151:7110
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000585
VERSION     KCWK01000585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19151:7110"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66323.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       400..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          156 c          125 g          101 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcgtctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttctgt tcacgcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgtaccc gcagcagagg
      181 caacattgac aatagttatg tacagtggta ccagcagcgc ccggacagtg ccccgaccac
      241 agtgatttac agagataacc aaagagcctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctggg ctgaagtctg aggacgaggc
      361 tgactactac tgtcagtcta ctgatggcaa ctacaatcgg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000586             498 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:9046:21863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000586
VERSION     KCWK01000586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 498)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9046:21863"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..460
                     /note="immunoglobulin light chain variable region"
     V_region        130..460
     V_segment       130..423
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>432
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66324.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       424..460
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        461..>498
                     /gene="IGLC"
BASE COUNT           94 a          157 c          133 g          114 t
ORIGIN      
        1 acatggggag atttgggtga agcgcagctt cagctgtggg tacagaaggc aggactcagg
       61 acaatctcca gcatggcctg gttccctctc gtcctcaccc tcctcactca ctgtgcaggg
      121 tcctgggccc agtctgtgct gactcagcct ccctcagcgt ctgaggccgc caggaagagt
      181 gtctccatct cctgttctgg aagcagctcc aacatcggaa gtcatagtgt ctcctggtac
      241 cagcaagtcc caggaacagc tcccaaactc ctcatctatt atagtgatca acgagcctca
      301 ggtgtctctg accgattctc tggctctcag tctggcacgt cagcctccct ggccatcagt
      361 gggctccaga ccgaggatga ggctgattat tactgcgcag catgggatga tagcctgagg
      421 ggttacatct tcggtgctgg gacccggctc gccgtcctag gtcagcccaa ggcttccccc
      481 acggtcactc tgttcccg
//
LOCUS       KCWK01000587             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:20403:6433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000587
VERSION     KCWK01000587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20403:6433"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66325.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          161 c          121 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctgggatc cccaatcgag
      301 tctctggctc caaggagacc tcaaataaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000588             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:22905:16896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000588
VERSION     KCWK01000588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22905:16896"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..403
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66326.1"
                     /translation="DYHCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           98 a          163 c          113 g          105 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagtcagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacacacac tggtaccaac agaagccagg gagtcccccc cgatatcttc
      241 tgaaatacaa atcagacaca gaccagggcc aggggtctgg agtccccagc cgcttctctg
      301 gatccaaaga tccttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctatcactgt gccattggtc acagcagcgg tccatacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000589             339 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:14056:17565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000589
VERSION     KCWK01000589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 339)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14056:17565"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..301
                     /note="immunoglobulin light chain variable region"
     V_region        10..301
     V_segment       10..263
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <226..>273
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66327.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       265..301
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        302..>339
                     /gene="IGLC"
BASE COUNT           74 a          104 c           96 g           65 t
ORIGIN      
        1 acatgggcag tgtccccagg acagacggcc aggatcacct gtgggggaga caacattgga
       61 agtcaaagtg tgcactggta ccagcacaag ccaccgcagg cccctgtact ggtcatcttt
      121 tattataccg aacggccctc aggaatccct gagcgattct ctggctccaa atcagggaac
      181 accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta ttactgtcag
      241 gtgtgggaca caactattga tcacggcttc ttcggaggag ggacccggct gaccgtccta
      301 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000590             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:28017:17754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000590
VERSION     KCWK01000590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:28017:17754"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    135..401
                     /note="immunoglobulin light chain variable region"
     V_region        135..401
     V_segment       135..364
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <332..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66328.1"
                     /translation="DYYCQTWDTGIVSF"
     J_segment       365..401
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>439
                     /gene="IGLC"
BASE COUNT           82 a          147 c          114 g           96 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctctga gcagtggaca cagcagctac accatcgcat ggcatcagca
      181 ccagcaaggg aaggcccctc ggtatttgat gtggcttaaa agtgatggca gccacagcaa
      241 gggggacggg atccctgatc gcttctcagg ctccagttcc ggggctgagc gctacctcac
      301 catctccaat ttccagtctg aggatgaggc tgattattac tgtcagacct gggatactgg
      361 cattgtgtca ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc
      421 ctcggtcact ctcttcccg
//
LOCUS       KCWK01000591             358 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:17053:13030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000591
VERSION     KCWK01000591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 358)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 358)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..358
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17053:13030"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..320
                     /note="immunoglobulin light chain variable region"
     V_region        7..320
     V_segment       7..283
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <245..>292
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66329.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       285..320
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        321..>358
                     /gene="IGLC"
BASE COUNT           71 a          116 c           93 g           78 t
ORIGIN      
        1 acatgggccg ccctcagtgt ctggggcccc agggcagagg gtcaccatct cctgcactgg
       61 gagcagctcc aacattggag gttattatat atcctggtac cagcagctcc caggaacggc
      121 ccccaaactc ctcgtctatg acaataataa gcgaccctca ggggtttctg accgattctc
      181 tggctccaag tctggttcct cagccaccct gaccatcact gggctccaga ctgaggatga
      241 ggctgattat tactgccagt cctatgacag cagtctgagt gctcgggtat tcggcggagg
      301 gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000592             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:28232:9104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000592
VERSION     KCWK01000592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:28232:9104"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66330.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       215..251
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           58 a           88 c           77 g           66 t
ORIGIN      
        1 acatggggga agtcatagtg tatcctggta ccagcagctc ccaggaacag ctcccaaact
       61 cctcatctat tatgatgatc aacgagcctc gggtgtctct gaccgattct ctggctccag
      121 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      181 ttactgcgca gcatgggatg atagcctgag aggttacatc ttcggtgatg ggacccggct
      241 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000593             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:22913:20959
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000593
VERSION     KCWK01000593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22913:20959"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66331.1"
                     /translation="DYYCQVWGSRSDHPVF"
     J_segment       399..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          151 c          137 g           93 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag ggtcacctgt gggggaggca
      181 acattggaag taattatgtt cactggtacc agcagaagcc accgcaggcc cctgttcagg
      241 tcatctatgc tgataacaaa cggccctcag ggatccctga acgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtggggcagt cgtagtgatc atccggtctt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000594             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:24623:19057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000594
VERSION     KCWK01000594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:24623:19057"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66332.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           89 a          143 c          125 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatttatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000595             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:20761:8475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000595
VERSION     KCWK01000595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20761:8475"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66333.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          143 c          139 g           94 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttggaagtga agttgtgaac tggtaccagc agaagccagc gcacgcccct gtgctggtca
      241 tctatgctaa tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg gggtgaggct gactattact
      361 gtcaggtgtg ggacatgcgt agtgatcaac cgctattcgg cggagggact cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000596             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:13251:15920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000596
VERSION     KCWK01000596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13251:15920"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66334.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          152 c          114 g          117 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcggtg
      181 ttggtaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcatc aggggtctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000597             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:17816:14907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000597
VERSION     KCWK01000597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17816:14907"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..295
                     /note="immunoglobulin light chain variable region"
     V_region        8..295
     V_segment       8..258
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <220..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66335.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       259..295
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        296..>333
                     /gene="IGLC"
BASE COUNT           66 a          102 c           87 g           78 t
ORIGIN      
        1 acatggggga agagtgtctc catctcctgt tctggaagca gctccaacat cggaagtcat
       61 agtgtctcct ggtaccagca agtcccagga acagctccca aactcctcat ctattatagt
      121 gatcaacgag cctcaggtgt ctctgaccga ttctctggct ctcagtctgg cacgtcagcc
      181 tccctggcca tcagtgggct ccagaccgag gatgaggctg attattactg cgcagcatgg
      241 gatgatagcc tgaggggtta catcttcggt gctgggaccc ggctcgccgt cctaggtcag
      301 cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000598             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:25982:10019
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000598
VERSION     KCWK01000598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:25982:10019"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66336.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           84 a          163 c          115 g          113 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctccagg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac gttggtggtt ataactctgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaactc atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagt ctgaggacga
      361 ggctgattat tactgttgtt cacattcaac cagtagcact tacgtcttcg gtcctgggac
      421 ccggctcacc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000599             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:22244:15523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000599
VERSION     KCWK01000599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:22244:15523"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66337.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          163 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctata ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaacc cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000600             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:12462:16342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000600
VERSION     KCWK01000600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12462:16342"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66338.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          143 c          132 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga attgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000601             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:15996:20054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000601
VERSION     KCWK01000601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15996:20054"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..266
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <230..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66339.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       271..305
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           68 a          104 c           91 g           80 t
ORIGIN      
        1 acatgggggg gcgcccgggc agagggtcac catctcctgc actgggagca gctccaacat
       61 tggaggttat tatgtgcagt ggtaccagca gcttccaggg acggccccca aactcctcat
      121 ctatgaaaat gataaacgac cctcaggggt ttctgatcga ttctctggct cccagtctga
      181 ttcctcagcc tccctgacca tcactggact ccagtctgag gatgaggctg attattactg
      241 ccagtcctat gacagcagct tgagtgttgt cttattcgga ggagggaccc ggctgaccgt
      301 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000602             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:13629:13831
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000602
VERSION     KCWK01000602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13629:13831"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66340.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          159 c          112 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccaacaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000603             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:8306:19200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000603
VERSION     KCWK01000603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8306:19200"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..433
                     /note="immunoglobulin light chain variable region"
     V_region        85..433
     V_segment       85..393
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66341.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       400..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           94 a          154 c          115 g          108 t
ORIGIN      
        1 acatggggga aagaggctgt gtccaccatg gcctggactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctccaagcct atgctgactc agccggcctc cctctcagca
      121 tctcctggag catcagccag tctcacatgc accttcagcg gtggcatcaa tgttgctggc
      181 taccacatat actggtacca gcagaagcca gggagtcccc cccggtatct tctgaggtac
      241 aaatcagact cagataaggg ccaggggtct ggagtcccca gccgcttctc tggatccaaa
      301 gatgcttcag cgaacacagg gattttacgc atctctggac tccagtctga ggatgaggct
      361 gactattact gtgccatcgg acacagcagc ggtgattata tcttcggtgc tgggacccgg
      421 ctcatcgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01000604             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:16180:12201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000604
VERSION     KCWK01000604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16180:12201"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66342.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          101 a          137 c          123 g          105 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg aagtgacaca
      121 gtcaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagcaat
      181 tctggcaaat aattatgctc agtggttcca gcagaagcca gaccaggccc ctgtgttggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gttgacagca gtgcccatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000605             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:24644:19685
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000605
VERSION     KCWK01000605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:24644:19685"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66343.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          160 c          122 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcaacgggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcaga tgtatgacag tagtgatgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000606             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:12887:15694
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000606
VERSION     KCWK01000606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12887:15694"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66344.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          158 c          126 g          111 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtctcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcag ctcccaggca
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc tcagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcttggg atgatagcct gagcggttac atcttcggtg
      421 ctgggacccg gctcgccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01000607             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:6949:18143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000607
VERSION     KCWK01000607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:6949:18143"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66345.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          158 c          123 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca acctcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000608             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17348:11299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000608
VERSION     KCWK01000608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17348:11299"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..423
                     /note="immunoglobulin light chain variable region"
     V_region        81..423
     V_segment       81..386
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66346.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       387..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           87 a          157 c          107 g          110 t
ORIGIN      
        1 acatggggga ggctgtgtcc accatggcct ggactcctct cctcctcctg ctcctctctc
       61 actgcacagg ttccctctcc cagcctgtgc tgacccagcc aacctccctc tcagcatctc
      121 cgggagcatc agccagactc agctgcacct tgagcagtgg caatgttggt agttacagca
      181 tattctggta ccagcagaag ccagggagtc ctccccggta ccttctttac tactactcag
      241 actcaagtaa ccaggactct ggagtcccca gccgcttctc tggatcgaaa gatgcttcag
      301 ccaatgcagg gcttttactg atctctgggc tccagtctga agatgaggct gactattact
      361 gtgccacatg gcacagcagc gcttcttaca tcttcggtgc tgggacccgg ctcaccgtcc
      421 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01000609             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:21308:19411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000609
VERSION     KCWK01000609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21308:19411"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66347.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          163 c          119 g          111 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggtg gtaaaaacat gtactggtac cagcagaagc cagggcgcgc tcccaggttt
      241 ttcctgtact acaactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcacgta tatgacagta gtactaatgt gttattcgga
      421 ggagggaccc gtctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01000610             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:17480:15476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000610
VERSION     KCWK01000610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17480:15476"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66348.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          144 c          133 g           94 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gaactgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagacg
      181 acattggaac taaaactgta cactggtacc agcagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgatagtaaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000611             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:11523:17060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000611
VERSION     KCWK01000611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11523:17060"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66349.1"
                     /translation="DYYCSAWDSSLTGGLF"
     J_segment       406..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           97 a          155 c          123 g          106 t
ORIGIN      
        1 acatggggag cttcagctgt ggctagagaa gacaggactc aggacaatct ccagcatggc
       61 ctgcttccct ctcatcctca ccgtcctcac tcactgtgca ggatcctggg cccagtctgt
      121 gctgactcaa ccaccctcag cgtctggggc ccccgggcag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaatta tgtatactgg taccagcagt tctcagggaa
      241 ggcccccaaa ctcctcatcc ataataataa tcagcgaccc tcaggggtcc ctgatcgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agtccgagga
      361 tgaggctgat tattactgct cagcatggga tagcagtctg accggtggct tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01000612             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:7198:15669
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000612
VERSION     KCWK01000612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7198:15669"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66350.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          160 c          112 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gagactgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000613             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:11667:6912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000613
VERSION     KCWK01000613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11667:6912"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..434
                     /note="immunoglobulin light chain variable region"
     V_region        88..434
     V_segment       88..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66351.1"
                     /translation="DFFCAIGHSSGPYIF"
     J_segment       400..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>474
                     /gene="IGLC"
BASE COUNT           90 a          162 c          115 g          107 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcaactcctg gagcatcagc cagtctcacg tgcaccttca gcggtggcat caatgttgct
      181 ggctaccaca tccactggta ccagcagaag ccagggagtc ccccccggta tcttctgagt
      241 aacaaatcag actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt caacgaacac aggcatttta cacatctctg ggctccagtc tgaggatgag
      361 gctgactttt tctgtgccat tgggcacagc agcggtcctt acatcttcgg tgctgggacc
      421 cggctcaccg tcctcggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000614             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:19210:8535
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000614
VERSION     KCWK01000614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19210:8535"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66352.1"
                     /translation="DYYCHVYDSSANVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          160 c          124 g          113 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcactct gagcagtgac
      181 ctcagtgttg gtggtaaaag catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt tctactactc cgactcagac aagcagttgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcac gtatatgaca gtagtgctaa tgtgttattc
      421 ggaggaggga cccgactgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01000615             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:10228:10364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000615
VERSION     KCWK01000615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10228:10364"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..431
                     /note="immunoglobulin light chain variable region"
     V_region        105..431
     V_segment       105..398
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66353.1"
                     /translation="DYHCSAGFGSGYSWQWVF"
     J_segment       399..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>473
                     /gene="IGLC"
BASE COUNT           93 a          150 c          132 g           98 t
ORIGIN      
        1 acatggggga tcctggcttc agaagcagca tctgggacat gtcagccatg gcctggacgc
       61 ctctcctcct cagcctcctc gctcactgca caggctctgt ggcctcctat gagctgactc
      121 agccaccctc agtgtcggtg tccccaggac agacagccag catcacctgc tctggagata
      181 aattggggaa tgtttatgct tattggtacc agcagaagcc aggccaggcc cctatactgg
      241 tcatctacaa agatagcaac cggccctcag ggatccctga ccgattctct ggctccaact
      301 cagggaacac ggccaccctg accatcagca gggtcgaggc tggggatgag gccgactatc
      361 actgttctgc aggctttggc agtgggtaca gctggcagtg ggttttcggc ggagggaccc
      421 ggctaaccgt cgtaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000616             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:8846:8896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000616
VERSION     KCWK01000616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:8846:8896"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66354.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          160 c          110 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag tatattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcaggacttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000617             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:21652:5387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000617
VERSION     KCWK01000617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21652:5387"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..437
                     /note="immunoglobulin light chain variable region"
     V_region        106..437
     V_segment       106..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66355.1"
                     /translation="EYYCCSHAGSDIFVLF"
     J_segment       403..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>477
                     /gene="IGLC"
BASE COUNT           85 a          159 c          125 g          108 t
ORIGIN      
        1 acatggggct ggggtctcag gaggcagcgc tctcgggaca tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagcctcgct cagtgtctgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgaca tcggcggtta taactatgtc tcctggtacc aacagcatcc agacacagcc
      241 cccaaactca tgatttatga ggtcactaag cggccctcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccaggc tgaggacgag
      361 gctgaatatt actgctgctc acatgcaggc agtgatattt tcgtgttatt cggaggaggg
      421 acccggctga ccgtccttgg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000618             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:9676:15973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000618
VERSION     KCWK01000618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9676:15973"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66356.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       391..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          138 c          139 g           99 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagg
      121 caccctcgat ttcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtgaac tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tgtatgctga tagcgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacatgaat agtcatcatc tgttattcgg aggggggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000619             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:17607:7858
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000619
VERSION     KCWK01000619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17607:7858"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66357.1"
                     /translation="DYYCQVWDTSIDHGLF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          146 c          127 g           96 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtgaggg agacaacatt
      181 ggaagtcaaa gtgtgcactg gtaccagcac aagccaccgc aggcccctat actggtcatc
      241 ttttattata ccgaacggcc ctcaggaatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acacaagtat tgatcacggc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000620             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10335:3365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000620
VERSION     KCWK01000620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10335:3365"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66358.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          147 c          132 g           96 t
ORIGIN      
        1 acatgggggg ggggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt caaagtgtgc actggtacca gcacaagcca ccgcaggccc ctgtactggt
      241 catcttttat tataccgaac ggccctcagg aatccctgag cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacacaa ctattgatca cggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000621             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20476:14638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000621
VERSION     KCWK01000621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20476:14638"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66359.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          161 c          123 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggttc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000622             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:18919:11407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000622
VERSION     KCWK01000622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18919:11407"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66360.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          148 c          128 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatgac ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000623             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:10324:13167
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000623
VERSION     KCWK01000623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10324:13167"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66361.1"
                     /translation="DYYCAAWDDSLSSLFF"
     J_segment       396..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           91 a          150 c          119 g          109 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gataatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 accctcaacg tctggggctc ccgggcagag tgtcaccatc tcttgctctg gaagcagctc
      181 caacattgga agtaattatg tatactggta ccagcagctc ccaggaacgg cccccaaact
      241 cctcatctat tataataatc agcgaccctc aggggtccct gaccgattct ctggctctaa
      301 gtctggcact tcagcctccc tggccatcac tggtctccga tctgaggatg aggctgatta
      361 ttactgtgca gcatgggatg acagcctgag cagtttgttc ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000624             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:8594:13636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000624
VERSION     KCWK01000624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8594:13636"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66362.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          154 c          112 g          116 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgagcagt ggcttcagtg
      181 ttggtactta caggatattc tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 ttaactacca cacagactca gataaacacc aggactctgg agtccccagc cgcttctttg
      301 gatccaaaga tgctccggcc aatgcaggga ttttactcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttatgtctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000625             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:12583:15813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000625
VERSION     KCWK01000625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12583:15813"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66363.1"
                     /translation="HYYCQVWDINSDHVLF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          139 c          134 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg gtctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgat gttgtgaatt ggtaccacca gaagccaccg caggcccctg tactggtcat
      241 ctatgctaat agcgatcggc cctcagggat ccctgagcga ttctctggct ccatatcagg
      301 gaacacggcc accctgacca tcaacggggt cgaggccggg gatgaggctc actattactg
      361 tcaggtgtgg gacattaata gtgatcatgt gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000626             400 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:23062:2362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000626
VERSION     KCWK01000626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 400)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 400)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:23062:2362"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..362
                     /note="immunoglobulin light chain variable region"
     V_region        14..362
     V_segment       14..322
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <290..>334
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66364.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       325..362
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        363..>400
                     /gene="IGLC"
BASE COUNT           82 a          128 c           97 g           93 t
ORIGIN      
        1 acatgggctc tccaagccta tgctgactca gccggcctcc ctctcagcat ctcctggagc
       61 atcagccagt ctcacatgca ccttcagcgg tggcatcaat gttgctgact accacgtaca
      121 ctggtatcag cagaagccag ggagtccccc ccggtatctt ctgaggtaca aatcagactc
      181 agataagggc ctgggctctg gagtccccag ccgcttctct ggatccaaag atgcttcagc
      241 gaatacaggg attttacaca tctctggttt ccagtctgag gatgaggctg actattactg
      301 tgccattggc cacggcagcg gtgattacat cttcgctact gggacccggc tcaccgtcct
      361 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000627             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:9721:19130
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000627
VERSION     KCWK01000627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9721:19130"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66365.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       397..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          149 c          136 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta aatatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
      241 atctatgctg ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 ggaaacaccg ccaccctgac catcagcggg gtcgaggccg ggtatgaggc tgactatttc
      361 tgtcaggtgt gggacgatag tagtgatcat ccggtgttcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000628             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:18741:18380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000628
VERSION     KCWK01000628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18741:18380"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..421
                     /note="immunoglobulin light chain variable region"
     V_region        103..421
     V_segment       103..389
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66366.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       390..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           93 a          138 c          127 g          101 t
ORIGIN      
        1 acatggggtg tgggctcaga agcagagctc tggggtgtct ccaccatggc ctggactcct
       61 ctctggctca ccctcctcag tctttgcaca ggttctgtgg tttcttctga gctgactcag
      121 gaccctgcag tgtctgtggc cttgggacag acagtcagga tcacctgcca aggagacagc
      181 ctcagaagtt attatgcaag ttggtaccag cagaagccag gccaggcccc tatactggtc
      241 gtctatggta acaattaccg gccctcaggg atcccagagc gattctctgg ctccagtaca
      301 cgaaacacag cttccttgac catcactggg gctcaggtgg aagatgaggc tgactattac
      361 tgtgactcct gggacagccg cggaacccaa ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000629             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:11545:5367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000629
VERSION     KCWK01000629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11545:5367"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66367.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          155 c          118 g          106 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtctccatc tcctgttctg gaagcagctc
      181 caacatcgga agtcatagtg tctcctggta ccggcacctc ccaggaacag ctcccaaact
      241 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctccaa
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcatgggatg ataacctgag cggttacatc ttcggttctg ggacccgact
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000630             279 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:8795:10413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000630
VERSION     KCWK01000630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 279)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:8795:10413"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..241
                     /note="immunoglobulin light chain variable region"
     V_region        8..241
     V_segment       8..203
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <166..>213
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66368.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       204..241
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        242..>279
                     /gene="IGLC"
BASE COUNT           55 a           80 c           87 g           57 t
ORIGIN      
        1 acatggggtg tgcagtggta ccagcagacg ccaccgcagg cccctgtact ggtcatttat
       61 ggtgataggg aacggccctc agggatccct gagcgattct ctggctccaa cccagggaac
      121 accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta ttactgtcag
      181 gtgtgggata gtagtagtaa atatgtgtta ttcggaggag ggacccggct gaccgtccta
      241 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000631             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:25541:14907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000631
VERSION     KCWK01000631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:25541:14907"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..445
                     /note="immunoglobulin light chain variable region"
     V_region        109..445
     V_segment       109..402
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66369.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          154 c          126 g          109 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg tcaccatctc ctgcactggg
      181 agcagctcca acatcggggc gggttattat gtatcctggt accagcagtt cccaggaaca
      241 gcccccaaac tcctcatcta tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggtac ctcagcctcc ctgaccatca ctggactcca atctgaggat
      361 gaggctgatt attactgctc agcatgggat agcagcctga gtattaatta catcttcggt
      421 ggtgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000632             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:13954:8356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000632
VERSION     KCWK01000632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:13954:8356"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..380
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66370.1"
                     /translation="DYFCQVWDSISDHPLF"
     J_segment       389..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           90 a          148 c          131 g           92 t
ORIGIN      
        1 acatgggggt ctcaggaggc agcattgacg gtgcctcagc catggcctgg acccttctcc
       61 tcctcggcct cctcgctcac tgcacagcct ctgcgacctc ctatgagctg actcagccac
      121 cctcggtgtc agcggcctca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaactaaata tgtgcactgg taccagcaga agccagcgca ggcccctgtg caggtcattt
      241 atggtgatac caaacggccc tcagggatcc ctgagcgatt ctctggctcc aactcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tatttctgtc
      361 aggtgtggga cagtattagt gatcatccct tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000633             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:20896:11940
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000633
VERSION     KCWK01000633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20896:11940"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..401
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66371.1"
                     /translation="DYYCSSYEGTNSFIF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          158 c          122 g          106 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcagcgct ctcaggacgt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggaccctg ggctcaggct gccctgactc
      121 agcctccctc tgtgtctggg tctcccggac agtcggtcac catctcctgc acgggaacca
      181 gcagtgacat cggtggttat aactatgtct cctggtacca gcagcaccca ggcaaagccc
      241 ccaaactcat gatttatgat gtcagtaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaaatc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgcagctca tatgaaggca ccaacagttt catcttcggt gttgggaccc
      421 ggctcaccgt actaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000634             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:18355:5011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000634
VERSION     KCWK01000634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18355:5011"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66372.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          156 c          117 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacgtacac tggtatcagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc tgggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aatacaggga ttttacacat ctctggtttc cagtctgagg
      361 atgaggctga ctattactgt gccattggcc acggcagcgg tgattacatc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000635             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:3874:8464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000635
VERSION     KCWK01000635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:3874:8464"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66373.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          159 c          114 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tgctgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000636             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:3693:17698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000636
VERSION     KCWK01000636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:3693:17698"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    60..381
                     /note="immunoglobulin light chain variable region"
     V_region        60..381
     V_segment       60..345
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <309..>353
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66374.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       349..381
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        382..>419
                     /gene="IGLC"
BASE COUNT           86 a          131 c          116 g           86 t
ORIGIN      
        1 acatgggctg gacccttctc ctcctcggcc tcctcgctta ctgcacaggc tctgcgacct
       61 cctatgaact gactcagtca ccctcagtgt cagcggcctc aggacagccg gccaggatca
      121 cctgtggggg agacaacatt ggaattaaaa ctgtacactg gtaccagcag aagccaccgc
      181 agggccctgt attggtcatc tttgctgata gtaagcggcc ctcagggatc cctgagcgat
      241 tctctggctc caactcaggg aacaccgcca ccctgaccat cagcagggtc gaggccgggg
      301 atgaggctga ctattactgt caggtgtggg acagtagtag taaatggata ttcggcgggg
      361 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000637             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:24650:9965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000637
VERSION     KCWK01000637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24650:9965"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..336
                     /note="immunoglobulin light chain variable region"
     V_region        12..336
     V_segment       12..298
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <261..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66375.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       300..336
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           80 a          116 c          104 g           74 t
ORIGIN      
        1 acatgggggc ctcctatgat ctgactcagc caccctcggt gtcagtgtcc ccaggacaga
       61 cggccaggat cacctgtggg ggagacaaca ttggaagtca aagtgtgcac tggtaccagc
      121 acaagccacc gcaggcccct gtactggtca tcttttatta taccgaacgg ccctcaggaa
      181 tccctgagcg attctctggc tccaaatcag ggaacaccgc caccctgacc atcagcgggg
      241 tcgaggccgg ggatgaggct gactattact gtcaggtgtg ggacacaact attgatcacg
      301 gcttattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      361 tcactctctt cccg
//
LOCUS       KCWK01000638             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:20639:10355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000638
VERSION     KCWK01000638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20639:10355"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66376.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          157 c          126 g           99 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtggacac
      181 aggagctaca ccatcgcgtg gcatcagcag cagcaaggga aggcccctcg atacttgatg
      241 tggcttaaaa gtgatggcag ccacagcaag ggggacggga tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattatt gtcagacgtg ggatattggc atttgggtgt tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000639             348 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:14445:6052
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000639
VERSION     KCWK01000639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 348)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:14445:6052"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..310
                     /note="immunoglobulin light chain variable region"
     V_region        8..310
     V_segment       8..274
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <238..>282
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66377.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       278..310
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        311..>348
                     /gene="IGLC"
BASE COUNT           76 a          104 c          102 g           66 t
ORIGIN      
        1 acatgggcac cctcagtgtc agcggcctca ggacagccgg ccaggatcac ctgtggggga
       61 gacaacattg gaactaaaac tgtgcactgg taccaacaga agccaccgca gggccctcta
      121 ttggtcatct ttgctgatag tagacggccc tcagggatcc ctgagcgatt ctctggctcc
      181 aactcaggga acaccgccac cctgaccatc agcagggtcg aggccgggga tgaggctgac
      241 tattactgtc aggtgtggga cagtagtagt aaatggatat tcggcggggg gacccggcta
      301 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000640             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:16690:12057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000640
VERSION     KCWK01000640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16690:12057"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66378.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          153 c          114 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtactgac tcagcctccc
      121 tcagcgtctg aggccgccgg gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta atagtgtatc ctggtaccaa caactcccag aaacggctcc caaactcctc
      241 atgtattata atcatcggcg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacttcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagtat gggatgatag cctgaccggt tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000641             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:13005:15834
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000641
VERSION     KCWK01000641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13005:15834"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..296
                     /note="immunoglobulin light chain variable region"
     V_region        8..296
     V_segment       8..259
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66379.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       261..296
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>335
                     /gene="IGLC"
BASE COUNT           74 a          101 c           95 g           65 t
ORIGIN      
        1 acatggggtc cccaggacag acggccagga tcacctgtgg gggagacaac attggaagtc
       61 aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc atcttttatt
      121 ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca gggaacaccg
      181 ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac tgtcaggtgt
      241 gggacacaag tcttgatcac ggcttatttg gaggagggac ccggctgacc gtcctaagtc
      301 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000642             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:8166:9454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000642
VERSION     KCWK01000642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:8166:9454"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66380.1"
                     /translation="DYYCCSRSSSSTYVF"
     J_segment       400..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           82 a          161 c          118 g          112 t
ORIGIN      
        1 acatgggggg gggtctcaga aggcagcgct ctcaggacgt ctccaccatg gcctggactc
       61 tgctcctcgt caccctcctc actcaaggca caggatcctg ggctcagtct gccccgactc
      121 agcctccctc tgtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacgt tggtggttat aactctgtct cctggtacca acaacaccca ggcaaagccc
      241 ccaaagtcat gatttttggt gtcaataatc ggccctctgg ggtctctgac cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagtct gaggacgagg
      361 ctgattatta ctgttgttca cgttcaagca gcagcactta cgtcttcggt cctgggaccc
      421 ggctcaccgt cctgggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000643             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:22671:6743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000643
VERSION     KCWK01000643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22671:6743"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66381.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          142 c          142 g           93 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttggaagtga agttgtgaac tggtaccagc agaagccagc gcaggcccct gtgctggtca
      241 tctatgctga tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg gggtgaggct gactattact
      361 gtcaggtgtg ggacatgcgt agtgatcaac cgctattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctttt cccg
//
LOCUS       KCWK01000644             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12320:2447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000644
VERSION     KCWK01000644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12320:2447"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66382.1"
                     /translation="DYYCQSADSSGNHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          133 c          125 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc agtggttcca gcagaagcca ggccaggccc ctgtgttggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgaa cgattctcta gttccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggta gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagca gtggtaatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000645             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:18570:14445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000645
VERSION     KCWK01000645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18570:14445"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66383.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       402..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           86 a          161 c          124 g          105 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcagcgct ctcaggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggttat aactatgtct cctggtacca acaacatcca ggcacagccc
      241 ccaaactcgt gatttatgag gtcaatcagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tgacaacacg gcctccctga ccatctctgg cctccagcct gaggacgagg
      361 ctgattatta ctgcagctcg tatgcaggca gcgacacttt cgtgttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000646             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:25292:10890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000646
VERSION     KCWK01000646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:25292:10890"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    55..385
                     /note="immunoglobulin light chain variable region"
     V_region        55..385
     V_segment       55..346
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <313..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66384.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       348..385
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>423
                     /gene="IGLC"
BASE COUNT           77 a          136 c          109 g          101 t
ORIGIN      
        1 acatgggggt ctctccttct cactctgctg cttcactgca cagggtcctg ggcccagtct
       61 gtgctgacgc agccgccctc agcatctggg gcccccgggc agagggtcac catctcctgc
      121 tctgggagca gctccaacat cggggcgggt ttttatgtat cctggtacca gcagttccca
      181 ggaacagccc ccaaactcct catctttgaa aataataagc gaccctcagg ggtttctgac
      241 cgattctctg gctccaagtc tggttcctca gcctccctga ccatcactgg actccaatct
      301 gaggatgagg ctgattatta ttgttcatca tgggaaagca gcctgaattg ggtattcggc
      361 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      421 ccg
//
LOCUS       KCWK01000647             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:12834:9349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000647
VERSION     KCWK01000647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12834:9349"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66385.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          159 c          114 g          110 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgt ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggggggggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000648             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:9533:14450
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000648
VERSION     KCWK01000648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9533:14450"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66386.1"
                     /translation="DYFCAAWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          158 c          122 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggtaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtccag ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaacca gctccaacat cggaagtaat agtgtgtcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat ctattataat catcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attatttctg cgcagcatgg gatgatagcc tgaccggtta cattttcggt
      421 actgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000649             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:23679:17103
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000649
VERSION     KCWK01000649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23679:17103"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66387.1"
                     /translation="DYYCQSYDSSLSGVLF"
     J_segment       415..449
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           91 a          155 c          128 g          113 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcagtggg agcaactcca acattggata ctattatgtg cagtggtacc agcagcttcc
      241 agggacggcc cccaaactcc tcatctatga aaataataag cgaccctctg gggtttctga
      301 tcgattctct ggctcccagt ctggtacctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agtttgagtg gtgtcttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01000650             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:17848:11750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000650
VERSION     KCWK01000650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17848:11750"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66388.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          157 c          115 g          116 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcaag ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggatc
      181 catcagtgat attgggtctt ataatgctgt gtcttggtac caacagcatc caggcaaagc
      241 cccccaactc ataatttttg aggtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctgacaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgctgct catatgtagg cagcaacact tacatcttcg atgttgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000651             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:6929:3030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000651
VERSION     KCWK01000651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:6929:3030"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66389.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          159 c          112 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctgaagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000652             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:17220:3306
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000652
VERSION     KCWK01000652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17220:3306"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66390.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          162 c          121 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg acgcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000653             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:11996:19495
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000653
VERSION     KCWK01000653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11996:19495"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66391.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           91 a          161 c          111 g          110 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca ccctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaactaag caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt gctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000654             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:22927:9496
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000654
VERSION     KCWK01000654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22927:9496"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..451
                     /note="immunoglobulin light chain variable region"
     V_region        121..451
     V_segment       121..414
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66392.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       415..451
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT           92 a          157 c          125 g          115 t
ORIGIN      
        1 acatgggggc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcacttca cagttccagg gtcctgggcc
      121 cagtctgtgc tgacgcagcc gccctcagtg tctggggcgc ccgggcagag ggtcaccatc
      181 tcctgcactg ggagcagctc caacattgga gattattttg tgcagtggta ccagcacctt
      241 ccaggaacgg cccccaaact cctcatctat gaaaataata agcgaccctc agggatttct
      301 gatcgattct ctggctccca gtctggaacc tcagcctccc tgaccatcac tggactccag
      361 tctgaggatg aggctgatta ttactgccag tcctatgaca gcagtttgat tgctgtgtta
      421 ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCWK01000655             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:9253:12582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000655
VERSION     KCWK01000655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9253:12582"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..388
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66393.1"
                     /translation="DYYCSAWDSSLTGALF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          153 c          117 g          102 t
ORIGIN      
        1 acatggggag agaagacagg actcaggaca atctccagca tggcctgctt ccctctcatc
       61 ctcaccgtcc tcactcactg tgcaggatcc tgggcccagt ctgtgctgac tcaaccaccc
      121 tcagcgtctg gggcccccgg gcagagtgtc accatctcct gttctggaag cacctccaac
      181 atcggaagta attttgtata ctggtaccag cagttctcag ggaaggcccc caaactcctc
      241 atccataata atgatcagcg accctcaggg gtccctgatc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagtccg aggatgaggc tgattattac
      361 tgctcagcat gggatagcag tctgaccggt gccttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000656             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10661:10651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000656
VERSION     KCWK01000656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10661:10651"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66394.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          147 c          129 g           97 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gtactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000657             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:8879:3372
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000657
VERSION     KCWK01000657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:8879:3372"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..391
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66395.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       394..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          151 c          121 g          106 t
ORIGIN      
        1 acatgggaca cagaaggcag gactcaggat aatctccagc atggcctggt tccctctcgt
       61 actcaccctc ctcactcact gtgcagggtc ctgggcccag tctgtgctga ctcagccacc
      121 ctcagcgtct ggggctcccg ggcagagtgt caccatctct tgttctggaa gcatctccag
      181 cattggaagt agtgatgtat gttggtacca gcaactccca ggaacggccc ccaaactcct
      241 catcaattat agtgatcagc gactctcagg ggtccctgac cgattctctg gctctaagtc
      301 tggcacctca gcctccctgg ccatcactgg tctccgatct gaggatgagg ctgattatta
      361 ctgtgcagcc tgggatagca gcctgagcag tccggtattc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000658             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:12125:12142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000658
VERSION     KCWK01000658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12125:12142"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66396.1"
                     /translation="DYYCQVYDSSDVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          160 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatattgg taataaaaac atgtactggt accagcagaa gccagggagc gctcccaagt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgatgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000659             410 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:14879:20638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000659
VERSION     KCWK01000659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 410)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14879:20638"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    24..372
                     /note="immunoglobulin light chain variable region"
     V_region        24..372
     V_segment       24..333
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <300..>344
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66397.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       335..372
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        373..>410
                     /gene="IGLC"
BASE COUNT           82 a          133 c          101 g           94 t
ORIGIN      
        1 acatgggcac aggttccctc tccaagccta tgctgactca gccggcctcc ctctcagcat
       61 ctcctggaac atcagccagt ctcacatgca ccttcagcgg tggcatcaat gttgctgtct
      121 accacgtaca ctggtaccaa cagaagccag ggagtccccc ccggtatctt ctgaggtaca
      181 aatcagactc agataagggc cagggctctg gggtccccag ccgcttctct ggatccagta
      241 atgcttcagc gaacacaggg attttacgca tttctgggct ccagtctgag gatgaggctg
      301 actattactg tgccattggg cacagcagcg gtctttacat cttcggtgct gggacccggc
      361 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000660             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:21211:19959
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000660
VERSION     KCWK01000660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21211:19959"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66398.1"
                     /translation="AYYCQVWDSDSDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          150 c          129 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaagccac cgcaggcccc tatgcaggtc
      241 atctatgctg ataacaaacg gccctcaggg atccctgaga gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctattac
      361 tgtcaggtgt gggacagtga tagtgatcat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000661             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:20366:17968
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000661
VERSION     KCWK01000661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20366:17968"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66399.1"
                     /translation="DYYCAMWHSSASYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          163 c          111 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttgctagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tttactacta ctcagactca agtaaccacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tacttcggcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttcttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000662             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:17961:11303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000662
VERSION     KCWK01000662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17961:11303"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..434
                     /note="immunoglobulin light chain variable region"
     V_region        110..434
     V_segment       110..397
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66400.1"
                     /translation="DYYCQVWDSSSDHVFF"
     J_segment       398..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           91 a          150 c          138 g           93 t
ORIGIN      
        1 acatgggggc ccagcctggg cctcaggaag cagccttggc ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggcc tcctcgctca ctgcacaggc tctgcggcct cctatgaaat
      121 gactcagccg cgctcagtgt ctgtgtcccc aggacagacg gccaggatca cctgtggggg
      181 agacaacatt agaagtaaaa atgtgaattg gtaccagcag aagccaccgc aggcccccgc
      241 gctggtcatc tattatgata gcgaccggcc ctcagggatc cctgagcgat tctctggctc
      301 caactcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga
      361 ctattactgt caggtgtggg acagtagtag tgatcatgtg tttttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000663             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:20445:5971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000663
VERSION     KCWK01000663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:20445:5971"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..277
                     /note="immunoglobulin light chain variable region"
     V_region        7..277
     V_segment       7..238
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <205..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66401.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       240..277
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>315
                     /gene="IGLC"
BASE COUNT           64 a           95 c           82 g           74 t
ORIGIN      
        1 acatggggca tcaatgttgc tgtctaccac gtacactggt accaacagaa gccagggagt
       61 cccccccggt atcttctgag gtacaaatca gactcagata agggccaggg ctctggggtc
      121 cccagccgct tctctggatc cagtaatgct tcagcgaaca cagggatttt acgcatttct
      181 gggctccagt ctgaggatga gtctgactat tactgtgcca ttgggcacag cagcggtctt
      241 tacatcttcg gtgctgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg
      301 gtcactctgt tcccg
//
LOCUS       KCWK01000664             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:11232:7039
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000664
VERSION     KCWK01000664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11232:7039"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..237
                     /note="immunoglobulin light chain variable region"
     V_region        8..237
     V_segment       8..200
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <162..>209
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66402.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       203..237
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>275
                     /gene="IGLC"
BASE COUNT           51 a           86 c           82 g           56 t
ORIGIN      
        1 acatggggca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc atctatgctg
       61 ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactca gggaacaccg
      121 ccaccctgac catcagcggt gtcgaggccg ggtatgaggc tgactatttc tgtcaggtgt
      181 gggacgatag tagtgatcat ccggtattcg gcggagggac ccggctgacc gtcctaggtc
      241 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000665             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:9540:17138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000665
VERSION     KCWK01000665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:9540:17138"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66403.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       393..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          154 c          121 g          104 t
ORIGIN      
        1 acatgggggt acagaaggca ggactcagga caatctccag catggcctgg ttccctctcg
       61 tcctcaccct cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagcctc
      121 cctcagcgtc tgaggccgcc aggaagagtg tctccatctc ctgttcggga agcagctcca
      181 acatcggaag tcatagtgtc tcctggtacc agcaactccc aggaacagct cccaaactcc
      241 tcatctatta tagtgatcaa cgagcctcag gtgtctctga ccgattctct ggctcccagt
      301 ctggcacgtc agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt
      361 actgcgcggc atgggatgat agcctgagcg gttacatctt cggtggtggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01000666             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12181:13340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000666
VERSION     KCWK01000666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12181:13340"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66404.1"
                     /translation="DYFCQVWDSISDHPLF"
     J_segment       395..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          149 c          134 g           94 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca cagcctctgc gacctcctat gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaac taaatatgtg cactggtacc agcagaagcc agcgcaggcc cctgtgcagg
      241 tcatttatgg tgataccaaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 tctgtcaggt gtgggacagt attagtgatc atcccttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000667             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:9516:8604
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000667
VERSION     KCWK01000667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9516:8604"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..385
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66405.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       387..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           86 a          147 c          122 g          107 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gcatctgggg cccccgggca gagggtcacc atctcctgct ctgggagcag ctccaacatc
      181 ggggcgggtt tttatgtttc ctggtaccag cagttcccag gaacagcccc caaactcctc
      241 atctttgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggttcctcag cctccctgac catcactgga ctccaatctg aggatgaggc tgattattat
      361 tgttcatcat gggaaagcag cctgaattgg gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000668             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:7697:10391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000668
VERSION     KCWK01000668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7697:10391"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66406.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          163 c          109 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000669             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:9824:3868
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000669
VERSION     KCWK01000669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:9824:3868"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66407.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           95 a          153 c          115 g          114 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcg cagcctgtgc tgactcagcc aacctccctc
      121 tcagcatctc ctggagcatc agccagactc acctgcacct tgaacagtgg catcagtgtt
      181 ggtaattaca ggatattctg gtaccaccag aagccaggga gtcctccccg gtatcttctg
      241 aactaccaca cagactcaga tattcaccag ggctctggag tccccagccg cttctctggg
      301 tccaaggatg cttcggccaa tgcagggatt ttactcatct ctggactcca gtctgaggat
      361 gaggctgact attactgtat gatttggcac aacaatgctt attgggtatt cggcggaggg
      421 acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000670             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:19574:6509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000670
VERSION     KCWK01000670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:19574:6509"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66408.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       402..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          149 c          122 g          115 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggattctg ggttcaggct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatgt tgggtattat aacgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 ccaaactcat gatttatgac gtcattaagc ggccctcagg ggtttctgat cgcttctctg
      301 gctccaagtc tggcgacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gaaataattt tttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000671             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:25529:3857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000671
VERSION     KCWK01000671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:25529:3857"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66409.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          155 c          127 g          108 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa cagtgtcgcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtatcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatgatg atcaacgagc ctcgggtgtc tctgaccgat
      301 tctctggctc caggtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagaggttac atcttcggtg
      421 atgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01000672             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:12014:9239
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000672
VERSION     KCWK01000672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12014:9239"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66410.1"
                     /translation="DYSCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           81 a          157 c          127 g          107 t
ORIGIN      
        1 acatgggggg gggtctcagg agcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattct tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000673             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:21812:12861
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000673
VERSION     KCWK01000673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21812:12861"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66411.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           90 a          158 c          112 g          114 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtactga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttga gcagtggcat caatgttggt
      181 agttacagcg tattctggta ccagcagaag ccagggagtc ctccccggtt ccttctgtac
      241 tactactcag actcaagtaa acaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cggccaatgc aggcctttta ctgatctctg gggtccagtc tgaggatgag
      361 gctgactatt actgtgccat atggcacagc agcgcttctt acttcttcgg tactgggacc
      421 cggttcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000674             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:24268:9601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000674
VERSION     KCWK01000674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24268:9601"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..343
                     /note="immunoglobulin light chain variable region"
     V_region        13..343
     V_segment       13..309
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66412.1"
                     /translation="DYYCASYEGSNTFLF"
     J_segment       313..343
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>381
                     /gene="IGLC"
BASE COUNT           74 a          124 c           98 g           85 t
ORIGIN      
        1 acatgggggg ctcaggctgc cccgactcag cctccctctg tgtccgggtc tcctggacag
       61 tcggtcacca tctcctgcag tggaaccagc actaagattg ggtatcacaa tgctgtgtcc
      121 tggtaccaag agcatccagg caaagccccc aaactcatga tttttgacgt caataagcgg
      181 cccacaggga tctctgatcg gttctctggc tccaagtctg gcgacacggc ctccctgacc
      241 atctctgggc tccaggctga tgatgaggct gattattact gcgcctcata tgaaggcagc
      301 aacactttcc tcttcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      361 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000675             533 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:8765:6756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000675
VERSION     KCWK01000675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 533)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 533)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..533
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:8765:6756"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    165..495
                     /note="immunoglobulin light chain variable region"
     V_region        165..495
     V_segment       165..458
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <420..>467
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66413.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       459..495
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        496..>533
                     /gene="IGLC"
BASE COUNT          101 a          167 c          144 g          121 t
ORIGIN      
        1 acatgggggg actctccccc tctcagagta tgaagagagg gagagatttg ggtgaagcgc
       61 agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg gcctggttcc
      121 ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct gtgctgactc
      181 agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt tctggaagca
      241 gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga acagctccca
      301 aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga ttctctggct
      361 ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag gatgaggctg
      421 attattactg cgcagcatgg gatgatagtc tgagcggtta catcttcggt gctgggaccc
      481 ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000676             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:27441:19763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000676
VERSION     KCWK01000676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:27441:19763"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..407
                     /note="immunoglobulin light chain variable region"
     V_region        87..407
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66414.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       372..407
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>446
                     /gene="IGLC"
BASE COUNT           93 a          140 c          116 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aagatcacct gctctggaga tgcactgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcgat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gcagtggtta tggcttattc ggaggaggga cccggctgac cgtcctacgt cagcacaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000677             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:9374:14600
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000677
VERSION     KCWK01000677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9374:14600"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66415.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          120 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatctg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000678             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:21274:14373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000678
VERSION     KCWK01000678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:21274:14373"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66416.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       401..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          156 c          123 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa cagcatccag gcacagcccc
      241 caaagtcatg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat atacaggcat caacagttat atcttcggtg gtgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01000679             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:20808:2543
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000679
VERSION     KCWK01000679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20808:2543"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..229
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66417.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       233..269
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           65 a           83 c           92 g           67 t
ORIGIN      
        1 acatgggggg ggagacaata ttggaagtga agttgtcaac tggtaccagc agaagccacc
       61 gcaggcccct gtggtggtca tctatgctga ttatgaacgg ccctcaggga tccctgagcg
      121 attctctggc tccaaatcag ggaacacggc caccctgacc atcagcggag tcgaggccgg
      181 ggatgaggct gactattact gtcaggtttg ggacatttat attgatcatc cggtgttatt
      241 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01000680             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:25778:9108
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000680
VERSION     KCWK01000680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:25778:9108"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    49..382
                     /note="immunoglobulin light chain variable region"
     V_region        49..382
     V_segment       49..345
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <313..>354
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66418.1"
                     /translation="DYYCQTWDTGIVSF"
     J_segment       346..382
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>420
                     /gene="IGLC"
BASE COUNT           79 a          129 c          116 g           96 t
ORIGIN      
        1 acatggggga ggccataatg agtgtctctg ttttcagggt ctctctccca gcctgtgctg
       61 actcagtcgc cctctgcctc tgcctccctg ggagcctcgg tcaagctcac ctgtactctg
      121 agcagtggac acagcagcta caccatcgca tggcatcagc accagcaagg gaaggcccct
      181 cggtatttga tgtggcttaa aagtgatggc agccacagca agggggacgg gatccctgat
      241 cgcttctcag gctccagttc cggggctgag cgctacctca ccatctccaa tttccagtct
      301 gaggatgagg ctgattatta ctgtcagacc tgggatactg gcattgtgtc attcggagga
      361 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000681             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:14915:4011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000681
VERSION     KCWK01000681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14915:4011"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66419.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       409..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           98 a          156 c          116 g          110 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggaac atcaaccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctggct accacatata ctggtaccac cagaagccag ggagtccccc ccggtatctt
      241 ctgaggtaca aatcagactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc gaacacaggg attttacaca tctctggact ccagtctgag
      361 gatgaggctg actattactg tgccattgga cacagcagcg gtgattatat cttcggtggt
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000682             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:11581:18555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000682
VERSION     KCWK01000682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11581:18555"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..266
                     /note="immunoglobulin light chain variable region"
     V_region        3..266
     V_segment       3..229
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66420.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       230..266
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           62 a           96 c           72 g           74 t
ORIGIN      
        1 acatgggggt agttacagca tattctggta ccagcagaag ccagggagtc ctccccggta
       61 ccttctctac tactactcag actcaagtaa acaccagggc tctggagtcc ccagccgctt
      121 ctctggatcc aaagatgctt cggccaatgc aggcctttta ctgatctctg ggctccagtc
      181 tgaagatgag gctgactatt actgtgccat atggcacagc agcgcttctt acttcttcgg
      241 tactgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      301 cccg
//
LOCUS       KCWK01000683             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:26073:12694
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000683
VERSION     KCWK01000683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:26073:12694"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..439
                     /note="immunoglobulin light chain variable region"
     V_region        93..439
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66421.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       405..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>479
                     /gene="IGLC"
BASE COUNT           91 a          157 c          121 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagatacag atcagactca gataagggcc agggctctgg agtccccagc cggttctctg
      301 gatccaaaga tgctgcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattattgt gccattgggc acagcagcgg tccttacttc ttcggtggtg
      421 ggacccggct caccgtcctt ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000684             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:14373:21059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000684
VERSION     KCWK01000684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14373:21059"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66422.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          162 c          113 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaccaatg
      181 ttggtagtta caggatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacta ctcagactca actaagcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagtagcgc ttcttgcatc ttcggtcctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000685             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:15754:18794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000685
VERSION     KCWK01000685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15754:18794"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66423.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       392..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          140 c          135 g          103 t
ORIGIN      
        1 acatggggct gactttggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactttacag gctctgtggc ctcctatgag ttgcctcagc
      121 cacgctcatt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa tagtgtgcat tggtaccagc agaagccacc gcgggcccct gtattggtca
      241 tctctgttga tagcgaacgg ccctcaggga tccctgagcg attctctggt tccagatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggataatatt tataaatacg cggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000686             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:8036:2096
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000686
VERSION     KCWK01000686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8036:2096"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..242
                     /note="immunoglobulin light chain variable region"
     V_region        78..242
     V_segment       78..205
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <167..>214
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66424.1"
                     /translation="DYYCAAWDESLRGYIF"
     J_segment       206..242
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        243..>280
                     /gene="IGLC"
BASE COUNT           50 a           88 c           82 g           60 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caggtgtctc tgaccgattc tctggctcca agtctggcac
      121 gtcagccgcc ctggccatca gcgggctcca gaccgaggat gaggctgatt attactgcgc
      181 agcatgggat gaaagcctga ggggttacat cttcggtgct gggacccggc tcaccgtcct
      241 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000687             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:23538:3671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000687
VERSION     KCWK01000687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23538:3671"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66425.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       414..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          163 c          123 g          109 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccaacaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggc ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctaa tgtcttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01000688             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:21918:12009
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000688
VERSION     KCWK01000688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21918:12009"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..268
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <233..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66426.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       269..305
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           71 a          106 c           88 g           78 t
ORIGIN      
        1 acatgggggg tctcctggac agtcggtcac catctcctac actggaacca gcagtgacat
       61 tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagacc ccaaattcat
      121 gatttatgag gtcagtcaac ggccctcagg ggtctctgat cgtatctctg gctccaagtc
      181 tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg ctggttatta
      241 ctgcagctca tttgcaggta ccaacactgg cttaatcggt ggagggaccc ggctgaccgt
      301 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000689             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:9993:17077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000689
VERSION     KCWK01000689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9993:17077"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66427.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           90 a          162 c          118 g          110 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgttccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggta ataaaaacat gtactggtac caacagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aactaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcaggtg tttgacagta gtgctgtgtt attcggagga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000690             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:17960:18360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000690
VERSION     KCWK01000690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17960:18360"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66428.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           90 a          147 c          127 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtcaaag tgtacactgg taccagcaca agccaccgca ggcccctgtt ctgctcatct
      241 tttattatac cgaacggccc tcaggaatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cacaactatt gatcacggct tgttcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000691             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:7981:14531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000691
VERSION     KCWK01000691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:7981:14531"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66429.1"
                     /translation="DYYCSSWESSLNWLF"
     J_segment       410..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          151 c          130 g          114 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcaatg gacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtatctg gggcccccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac atcggggcgg gtttttatgt ttcctggtac cagcagttcc
      241 caggaacagc ccccaaactc ctcatctttg aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggttcct cagcctccct gaccatctct ggactccaat
      361 ctgaggatga ggctgattat tattgttcat catgggaaag cagcctgaat tggctattcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000692             285 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:13966:21950
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000692
VERSION     KCWK01000692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 285)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13966:21950"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..247
                     /note="immunoglobulin light chain variable region"
     V_region        5..247
     V_segment       5..208
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <175..>219
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66430.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       210..247
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        248..>285
                     /gene="IGLC"
BASE COUNT           55 a           87 c           72 g           71 t
ORIGIN      
        1 acatgggcgg gtttttatgt gtcctggtac cagcagttcc ctgggacagc ccccaaactc
       61 ctcatctttg aaaataataa gcgaccctca ggggtttctg accgattctc tggctccaag
      121 tctggttcct cagcctccct gaccatcact ggactccagt ctgaggatga ggctgattat
      181 tactgctcat catgggaaag cagcctgaat tgggtattcg gcggagggac ccggctgacc
      241 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000693             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:24369:4079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000693
VERSION     KCWK01000693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:24369:4079"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..380
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66431.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       384..416
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           93 a          141 c          128 g           92 t
ORIGIN      
        1 acatgggtca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc ttctcctcct
       61 cggcctcctc gcttactgca caggctctgc gacctcctat gaattgactc agtcaccctc
      121 agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca acattggaac
      181 taaaactgtg cactggtacc aacagaagcc accgcagggc cctgtattgg tcatctttgc
      241 tgatagtaga cggccctcag ggatccctga gcgattctct ggctccaact cagggaacac
      301 cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt actgtcaggt
      361 gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000694             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:10925:17743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000694
VERSION     KCWK01000694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10925:17743"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66432.1"
                     /translation="DYYCAMWHSSVYGLF"
     J_segment       404..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          155 c          113 g          116 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 ttctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cgattccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tacttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagtagtgt ttatggctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000695             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15365:18553
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000695
VERSION     KCWK01000695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15365:18553"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66433.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          163 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccccgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000696             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:22564:6492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000696
VERSION     KCWK01000696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22564:6492"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..252
                     /note="immunoglobulin light chain variable region"
     V_region        8..252
     V_segment       8..214
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <177..>224
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66434.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       219..252
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        253..>290
                     /gene="IGLC"
BASE COUNT           55 a           95 c           75 g           65 t
ORIGIN      
        1 acatgggcgg aagtcatagt gtctcctggt accagcagct cccaggaaca gctcccaaac
       61 tcctcatcta ttatagtgat caacgagcct caggtgtctc tgaccgattc tctggctccc
      121 agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat gaggctgatt
      181 attactgcgc agcatgggac gatagcctgc gcggctatat cttcggtgct gggacccggc
      241 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000697             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:21299:10569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000697
VERSION     KCWK01000697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21299:10569"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..387
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66435.1"
                     /translation="DYYCQSAENSAKYYIF"
     J_segment       398..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          108 a          133 c          121 g          104 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatggtc agtggttcca gcagaagcca ggtcaggccc ctgtgttggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgactctcta gttccagttc
      301 aggaacaaca cttaccttga ccatcactgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gcagagaaca gtgctaagta ttatatattc ggtgctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000698             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:22467:6111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000698
VERSION     KCWK01000698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22467:6111"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..425
                     /note="immunoglobulin light chain variable region"
     V_region        95..425
     V_segment       95..388
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66436.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          151 c          119 g          104 t
ORIGIN      
        1 atggggaggg aggcggcact ctcgggacat ctccaccatg gcctgggatc tgctcctctt
       61 caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc agcctccctc
      121 aatgtctggg tctcctggac agtcggtcac catctcctac actggaacca gcagtgacat
      181 tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagacc ccaaattcat
      241 gatttatgag gtcagtcaac ggccctcagg ggtctctgat cgtatctctg gctccaagtc
      301 tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg ctggttatta
      361 ctgcagctca tttgcaggta ccaacactgg cttaatcggt ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000699             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:10110:6045
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000699
VERSION     KCWK01000699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10110:6045"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..252
                     /note="immunoglobulin light chain variable region"
     V_region        8..252
     V_segment       8..214
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <180..>224
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66437.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       218..252
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        253..>290
                     /gene="IGLC"
BASE COUNT           62 a           87 c           79 g           62 t
ORIGIN      
        1 acatggggta ctggtaccag cagaagccag gaagcgctcc caggttattg ctgtattacc
       61 actccgactc agacaagcag ctgggacctg gggtccccaa tcgagtctct ggctccaagg
      121 agacctcaag taacacagcg tttttgctca tctctgggct ccagcctgag gacgaggccg
      181 attattactg tcaggtgtat gacagtagtg ccaacacgtt attcggagga gggacccggc
      241 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000700             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:7316:10184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000700
VERSION     KCWK01000700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7316:10184"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66438.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           88 a          145 c          131 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggca aatcagggaa
      301 caccgccacc ctgaccatca gcggggtcga ggccggggat gaggctgact attactgtca
      361 ggtgtgggac actactattg atcatggctt tttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000701             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:4383:10649
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000701
VERSION     KCWK01000701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:4383:10649"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66439.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       414..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          162 c          124 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctaa tgtcttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01000702             355 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:15048:9409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000702
VERSION     KCWK01000702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 355)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:15048:9409"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..317
                     /note="immunoglobulin light chain variable region"
     V_region        8..317
     V_segment       8..280
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>289
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66440.1"
                     /translation="DYYCQVWDSTSDHVFF"
     J_segment       281..317
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        318..>355
                     /gene="IGLC"
BASE COUNT           73 a          104 c          108 g           70 t
ORIGIN      
        1 acatgggcag ccgccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg
       61 gggagacgac attggaagta aatatgtgca ctggtaccag cagaagccac cgcaggcccc
      121 tgtgctggtc atctattatg atggcgaacg gccctcaggg atccctgagc gattctctga
      181 ctccaaatca gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc
      241 tgactattac tgtcaggtgt gggacagtac tagtgatcat gtgtttttcg gaggagggac
      301 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000703             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:20076:17778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000703
VERSION     KCWK01000703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:20076:17778"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66441.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           92 a          143 c          132 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca gtctctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaatta aaactgtgca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtaaacg gccctcgggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000704             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:7659:11968
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000704
VERSION     KCWK01000704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:7659:11968"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..393
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66442.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           94 a          154 c          116 g          105 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtcaccatc tcctgttctg gaagcacctc
      181 caacatcgga agcaataatg tatcctggta ccagcagctc ccaggaacag ctcccaaact
      241 cctcttttat tataatgatc aacgagcctc aggtgtctct gaccgattct cttgctccaa
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcatgggatg ataacctgag cggctacatc ttcggtgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000705             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:17850:14466
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000705
VERSION     KCWK01000705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17850:14466"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..426
                     /note="immunoglobulin light chain variable region"
     V_region        97..426
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66443.1"
                     /translation="VYYCAAWDNGLTSPVF"
     J_segment       395..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>465
                     /gene="IGLC"
BASE COUNT           91 a          155 c          115 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctcgt gctctggaag cagctccaac
      181 attggaacta attatgtata ctggtaccaa cacctcccag gaacggcccc caaactcctc
      241 atctattata gtaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgtttattac
      361 tgtgcagcat gggataacgg cctgaccagt ccggtattcg gaggagggac ccggctgacc
      421 gtcctaagtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000706             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:25615:15720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000706
VERSION     KCWK01000706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:25615:15720"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..449
                     /note="immunoglobulin light chain variable region"
     V_region        116..449
     V_segment       116..412
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66444.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           88 a          165 c          127 g          107 t
ORIGIN      
        1 acatgggggc agtgtggctg cctcagcaga gccctgagga gtctgcacca tggcctggac
       61 cccaatcctc ctcctcctcc tcactctcct ccttcactgc acagggtctc tctcccagcc
      121 tgtgttgact cagtcgccct ctgtctctgc ctccctggga gcctcggtca aactcacctg
      181 cactctgaac agtgggcaca gcagctacac catcgcatgg catcagcatc agcaagggaa
      241 ggccccccgg tacttgatgt ggcttaaaag tgatggcagc catagccagg gggacgggat
      301 ccctgatcgc ttttcaggct ccagctccgg ggctgagcgc tacctcacca tctccaacct
      361 ccagtctgag gatgaggctg attattactg tcagacctgg gatactgaca ttgtgttgtt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01000707             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:13625:7229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000707
VERSION     KCWK01000707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13625:7229"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66445.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          148 c          130 g           98 t
ORIGIN      
        1 acatgggctg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctccgatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa gagtgtgcac tggtaccagc acaagccacc gcaggcccct atcctggtca
      241 tctattatta taccgaacgg ccctcggcga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacactact attgatcatg gctttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000708             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:25559:19443
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000708
VERSION     KCWK01000708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:25559:19443"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66446.1"
                     /translation="DYYCSAWDSSLTGGFF"
     J_segment       409..446
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           97 a          156 c          123 g          108 t
ORIGIN      
        1 acatggggct cagcttcagc tgtggctaga gaagacagga ctcaggacaa tctccagcat
       61 ggcctgcttc cctctcatcc tcaccgtcct cactcactgt gcaggatcct gggcccagtc
      121 tgtgctgact caaccaccct cagcgtctgg ggcccccggg cagagtgtca ccatctcctg
      181 ttctggaagc agctccaaca tcggaagtaa ttatgtatac tggtaccagc agttctcagg
      241 gaaggccccc aaactcctca tccataataa taatcagcga ccctcagggg tccctgatcg
      301 attctctggc tccaagtctg gcacgtcagc ctccctggac atcagtgggc tccagtccga
      361 ggatgaggct gattattact gctcagcatg ggatagcagt ctgaccggtg gctttttcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01000709             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:19911:7581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000709
VERSION     KCWK01000709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19911:7581"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..223
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <197..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66447.1"
                     /translation="DYYCQSYDSLSAILF"
     J_segment       236..269
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           63 a           93 c           81 g           70 t
ORIGIN      
        1 acatgggggg agcagctcca acatcggggc gggttattat gtgcagtggt accagcagct
       61 tccaggaacg gcccccaaac tcctcatcta tgaaaatgat aagcgaccct caggggtttc
      121 tgatcgattc tctggctcca agtctggtac ctcagcctcc ctgaccatca ctggactcca
      181 gtctgaggat gaggctgatt attactgcca gtcctatgac agcctgagcg ctatattatt
      241 cgggggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01000710             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:19805:9787
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000710
VERSION     KCWK01000710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19805:9787"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66448.1"
                     /translation="DYYCQVWDISSDHVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          140 c          138 g           99 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctccgcgg cctcctttga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aacttgtgaa ctggtaccaa cagaggccac cgcaggcccc tgtgctggtc
      241 atgtatgctg atagcgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaatacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacattag tagtgatcat gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000711             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:14853:18038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000711
VERSION     KCWK01000711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14853:18038"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66449.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       404..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           85 a          162 c          125 g          106 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc gtgatttatg aggtcaatca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctgacaaca cggcctccct gaccatctct ggcctccagc ctgaggacga
      361 ggctgattat tactgcagct cgtatgcagg cagcgacact ttcgtgttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000712             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:15159:10787
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000712
VERSION     KCWK01000712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15159:10787"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..227
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66450.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       231..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           67 a           85 c           90 g           59 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaactaa aactgtgcac tggtaccaac agaagccacc
       61 gcagggccct gtattggtca tctttgctga tagtagacgg ccctcaggga tccctgagcg
      121 attctctggc tccaactcag ggaacaccgc caccctgacc atcagcaggg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg
      241 ggggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01000713             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:18121:11552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000713
VERSION     KCWK01000713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18121:11552"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66451.1"
                     /translation="DYYCAMWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          162 c          112 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000714             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:20500:12929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000714
VERSION     KCWK01000714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20500:12929"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66452.1"
                     /translation="DYYCCSYRTGNSWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           83 a          156 c          126 g          108 t
ORIGIN      
        1 acatggggtg gggtctcagg aggcagcgct ctcgggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcagtct gccctgactc
      121 agcctccctc agtgtccaag tctcttggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat tggtggttat gatggcgtct cctggtacca acagcactca gggacagccc
      241 ccagactcct gatttatgat gtcactaagc ggccctcagg ggtctcggat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctca ccatctctgg gctccagact gaggacgagg
      361 ctgattatta ttgttgctca tataggactg gaaacagttg gctattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000715             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:23005:5322
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000715
VERSION     KCWK01000715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23005:5322"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..452
                     /note="immunoglobulin light chain variable region"
     V_region        124..452
     V_segment       124..417
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66453.1"
                     /translation="DYYCAAWDDSLRGFIF"
     J_segment       420..452
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>492
                     /gene="IGLC"
BASE COUNT           93 a          157 c          132 g          110 t
ORIGIN      
        1 acatgggggg gtgaagcgca gcttcagctg tgggtacaga aggcaggact caggacaatc
       61 tccagcatgg cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg
      121 gcccagtctg tgctgactca gcctccctca gcgtctgagg ccgccaggaa cagtgtcgcc
      181 atctcctgtt ctggaagcag ctccaacatc ggaagtcata gtgtatcctg gtaccagcag
      241 ctcccaggaa cagctcccaa actcctcatc tattatgatg atcaacgagc ctcaggtgtc
      301 tctgaccgat tctctggctc caggtctggc acgtcagcct ccctggccat cagtgggctc
      361 cagaccgagg atgaggctga ttattactgc gcagcatggg atgatagcct gagaggtttc
      421 atcttcggtg atgggacccg gctcaccgtc ctgggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCWK01000716             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:14300:19984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000716
VERSION     KCWK01000716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14300:19984"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66454.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       387..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT          106 a          136 c          120 g           99 t
ORIGIN      
        1 atgggggtgg ttctaggagg ctgacctctg ggtgtctcac catgacctgg accactgttc
       61 tgctcccctt tctcactctc tgcacaggct ctgaggcctc ctatgacctg acacagccac
      121 cctcagtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gaaatactgg
      181 caaaaaaata tactcagtgg ttccagcaga agccaggcca gggccctaga ctggtgatat
      241 ataaagacag tgagaggccc tcagggatcc ctgagcgatt ctctagctcc agttcaggga
      301 caacagttac cttgaccatc agcggggccc agacagaaga tgaggctgac tattactgtc
      361 aatcagcaga cagaagtcct aatcatgtgt ttttcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000717             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:5942:3771
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000717
VERSION     KCWK01000717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5942:3771"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..443
                     /note="immunoglobulin light chain variable region"
     V_region        95..443
     V_segment       95..406
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66455.1"
                     /translation="DYYCAIWHSSGSYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           94 a          164 c          111 g          112 t
ORIGIN      
        1 acatggggcc actgcaggga aagaggctgt gtccaccatg gcctggactc ctctcctcct
       61 cctgctcctc tctcactgca caggttccct ctcccagcct gtgctgaccc agccaacctc
      121 cctctcagca tctccgggag catcagccag actcagctgc accttgagca gtggcatcaa
      181 tgttggtagt tacagcatat tctggtacca acagaagccc gggagtcctc cccggtacct
      241 tctctactac tactcagact caactaagca ccagggctct ggagtcccca gccgcttctc
      301 tggatccaaa gatgcttcag ccaatgcagg gcttttactg atctctggga tccagtctga
      361 agatgaggct gactattact gtgccatatg gcacagcagc ggttcttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01000718             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13737:18218
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000718
VERSION     KCWK01000718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13737:18218"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..389
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66456.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       394..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           87 a          149 c          118 g          108 t
ORIGIN      
        1 acatggggga ggcagcgctc tcaggacttc tccaccatgg tctgggctct gctcctcctc
       61 accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca gactccctct
      121 gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag cagtgatatt
      181 gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc caaactcatg
      241 atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg ctccaagtct
      301 ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc tgattattac
      361 tgcagctcat atggaggcag caatagttta ttcttcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000719             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:9632:7420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000719
VERSION     KCWK01000719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:9632:7420"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..277
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66457.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       278..314
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           74 a          108 c           91 g           79 t
ORIGIN      
        1 acatggggga gcatcagcca gtctcacatg caccttcagc ggtggcatca atgttggtgt
       61 ctaccacata cactggtacc aactgaagcc agggagtccc ccccggtatc ttctgaggta
      121 caaatcagac tcagataagg gccagggctc tggagtcccc agccgcttct ctggatccag
      181 taatgcttca gcgaacacag ggattttacg catctctggg ctccagtctg aggatgaggc
      241 tgactattac tgtgccattg gacacagcag cggtccttac atcttcggtg ctgggacccg
      301 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01000720             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:26572:19240
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000720
VERSION     KCWK01000720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:26572:19240"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66458.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       409..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           91 a          153 c          130 g          110 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctctccttc tcactctgct ggttcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagcatctgg ggcccccggg cagagggtca ccatctcctg
      181 cactgggagc agctccaaca tcggggcggg tttttatgta tcctggtacc agcagttccc
      241 aggaaaagcc cccaagctcc tcatctttga aaataacaag cgaccctcag gggtttctga
      301 ccgattctct ggctccaagt ctggttcctc agcctccctg accatcactg gactccaatc
      361 tgaggatgag gctgattatt attgttcatc atgggaaagc agcctgaatt gggtattcgg
      421 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01000721             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:10709:2946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000721
VERSION     KCWK01000721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10709:2946"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66459.1"
                     /translation="DYYCAMWHSSVYGLF"
     J_segment       401..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          154 c          114 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccga ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatac ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gtagtgttta tggcttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000722             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:17795:7377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000722
VERSION     KCWK01000722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17795:7377"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..279
                     /note="immunoglobulin light chain variable region"
     V_region        7..279
     V_segment       7..242
                     /gene="IGLV5-48"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <210..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66460.1"
                     /translation="DYYCAIGRSSAVLF"
     J_segment       246..279
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>317
                     /gene="IGLC"
BASE COUNT           68 a           91 c           86 g           72 t
ORIGIN      
        1 acatgggtgg tggcaccaat gttggtgact acactataca ctggtaccag cagaagccag
       61 ggagtcctcc ccggtatctt ctgaactaca aatcagactc agataatcac cagggctctg
      121 gagtccccag tcgcttctct gggtccaaag atgtttcagc gaacacaggg attttacgca
      181 tctctgggct ccagtctgag gatgaggctg actattactg tgccattggg cgcagcagcg
      241 ctgtattatt cggaggaggg acccggctga ccggcctagg tcagcccaag gctgccccct
      301 cggtcactct cttcccg
//
LOCUS       KCWK01000723             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10734:8727
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000723
VERSION     KCWK01000723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10734:8727"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..261
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <233..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66461.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       275..305
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           69 a          106 c           87 g           81 t
ORIGIN      
        1 acatgggggg tctcctggac agtcggtcac catctcctgc actggaacca gcagtgatgt
       61 tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc ccaaactcat
      121 gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg gctccaagtc
      181 tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg ctgattatta
      241 ctgcagctca tatgcaggca gcaacgcttt attcttcgga cgagggaccc gcctgaccgt
      301 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000724             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:22288:1990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000724
VERSION     KCWK01000724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22288:1990"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..404
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66462.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          158 c          118 g          110 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggtacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcagc ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct
      181 ggaagcacct ccaacatcgg aagcaataat gtatcctggt accagcagct cccaggaaca
      241 gctcccaaac tcctctttta ttataatgat caacgagcct caggtgtctc tgaccgattc
      301 tcttgctcca agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat
      361 gaggctgatt attactgcgc atcatgggat gataccctga gcggctacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000725             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:6341:18144
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000725
VERSION     KCWK01000725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6341:18144"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66463.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          150 c          123 g          115 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatca tgggttcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt ataacgctgt gtcttggtac caacagtatc caggcaaagc
      241 ccccaaactc ataatttttg acgtcattaa gcggccctcg ggggtctctg atcgcttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccggg ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagaaataat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000726             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:10221:9994
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000726
VERSION     KCWK01000726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:10221:9994"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..258
                     /note="immunoglobulin light chain variable region"
     V_region        5..258
     V_segment       5..222
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <186..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66464.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       226..258
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           67 a           84 c           85 g           60 t
ORIGIN      
        1 acatgggaga caacattgga actaaaactg tgcactggta ccaacagaag ccaccgcagg
       61 gccctgtatt ggtcatcttt gctgatagta gacggccctc agggatccct gagcgattct
      121 ctggctccaa ttcagggaac accgccaccc tgaccatcag cagggtcgag gccggggatg
      181 aggctgacta ttactgtcag gtgtgggaca gtagtagtaa atggatattc ggcgggggga
      241 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000727             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:12660:12276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000727
VERSION     KCWK01000727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12660:12276"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66465.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          148 c          131 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccgatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta agagtgtgca ctggtaccag cacaagccac cgcaggcccc tatcctggtc
      241 atctattatt ataccgaacg gccctcggcg atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacactac tattgatcat ggctttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000728             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:27287:6565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000728
VERSION     KCWK01000728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:27287:6565"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66466.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          156 c          122 g          104 t
ORIGIN      
        1 acatggggtg gctcaggaag cagagcctgg agcatctcca ccatggcctg ggctccactc
       61 ctcctcaccc tcctcgctca ctgcacaggg tcttgggctg aggttgtgtt cactcagccc
      121 cattctgtgt cggggtctcc ggggcagacg gtcaccatct cctgcacccg cagcagtggc
      181 agcattgaca acggctttgt gtactggtac cagcagcggc cgggcagcgc tcccaccact
      241 gtgatttaca aagataacca aagaccctct ggggtccctg atcggttctc tggctccatc
      301 gacagctcct ccaactctgc ctccctcacc atctctggac tgaaatctga ggacgaggct
      361 gactattact gtcagtctta tgacagcagc agtgtattat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000729             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:6982:9958
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000729
VERSION     KCWK01000729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:6982:9958"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66467.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          161 c          118 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctatgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatattgg taataaaaac atgtactggt accagcagaa gccagggagc gctcccaagt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000730             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:5128:6752
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000730
VERSION     KCWK01000730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5128:6752"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..436
                     /note="immunoglobulin light chain variable region"
     V_region        90..436
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66468.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       404..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           88 a          163 c          113 g          112 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc accaatgttg
      181 gtagttacag cattttctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaact aagcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatga ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc atttggcaca gcagcgcttc ttgcatcttc ggtcctggga
      421 cccggctcac cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000731             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:21536:18238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000731
VERSION     KCWK01000731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21536:18238"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..444
                     /note="immunoglobulin light chain variable region"
     V_region        115..444
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66469.1"
                     /translation="DYYCAAWDDSLTGYIF"
     J_segment       409..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>483
                     /gene="IGLC"
BASE COUNT           96 a          157 c          119 g          111 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tttggaagca gctccaacat cggaagtaat agtgtatcct ggtaccaaca attaccagaa
      241 acggctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacttcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgaccggtta catcttcggt
      421 cctgggaccc ggctcaccgt cctacgtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000732             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:10946:7565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000732
VERSION     KCWK01000732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10946:7565"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66470.1"
                     /translation="DYYCQVWDSSSDHWIF"
     J_segment       390..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          149 c          135 g           89 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgccc cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gactctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta aatatgtgca ctggtaccag cagaggccac cgcaggcccc tgtgcaagtc
      241 atctatactg atagcagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgcg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtgatcat tggatattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000733             371 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:17668:10372
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000733
VERSION     KCWK01000733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 371)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17668:10372"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..330
                     /note="immunoglobulin light chain variable region"
     V_region        8..330
     V_segment       8..296
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>305
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66471.1"
                     /translation="DYYCAIGLSSGYIF"
     J_segment       297..330
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        331..>371
                     /gene="IGLC"
BASE COUNT           76 a          117 c           96 g           82 t
ORIGIN      
        1 acatgggggc ctccctctca gcatctcctg gagcatcagc cagtctcaca tgtaccttca
       61 gcggtggcat caatgttgct ggctaccaca cacactggta ccagcagaag ccagggaggc
      121 ctccccggta tcttctgaga tacaaatcag actcagatag gggccagggc tctggagtcc
      181 ccagccgctt ctctggatcc aaagatgttt cagcgaacac agggatttta cgcatctctg
      241 ggctccagtc tgaggatgag gctgactatt actgtgccat tgggctcagc agcggttaca
      301 tcttcggtac tgggacccgg ctcaccgtcc caggtcagcc caaggcttcc cccacggtca
      361 ctctgttccc g
//
LOCUS       KCWK01000734             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:12718:5747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000734
VERSION     KCWK01000734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12718:5747"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66472.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          151 c          121 g          114 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcagga cacaggatcc tgggttcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat gttggatatt ataacgctgt gtcttggtac caacagcatc caggcaaagc
      241 ccccaaactc atgatttatg acgtcattaa gcggccctca ggggtttctg atcgcttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagaaataat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000735             353 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:21076:3268
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000735
VERSION     KCWK01000735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 353)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21076:3268"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..315
                     /note="immunoglobulin light chain variable region"
     V_region        8..315
     V_segment       8..278
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>287
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66473.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       279..315
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        316..>353
                     /gene="IGLC"
BASE COUNT           71 a          107 c           90 g           85 t
ORIGIN      
        1 acatgggggg agcatcagcc agactcagct gcaccttgag cagtggcatc aatgttggta
       61 gttacagcgt gttctggtac cagcagaggc cagggagtcc tccccggtac cttctgtact
      121 actactcaga ctcaagtaaa caccagggct ctggagtccc cagccgcttc tctggatcca
      181 aagatgcttc ggccaatgca ggccttttac tgatctctgg gatccagtct gaagatgagg
      241 ctgactatta ctgtgccata tggcacagca gcgcttctta cttcttcggt tctgggaccc
      301 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000736             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:9963:12583
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000736
VERSION     KCWK01000736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9963:12583"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66474.1"
                     /translation="DYYCQVWDINSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          139 c          136 g          101 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 gcaccctcga attcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaat
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atctatgctg atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcatcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacattaa tagtcatcat ctgttattcg gaggggggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000737             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:24758:17574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000737
VERSION     KCWK01000737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:24758:17574"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..406
                     /note="immunoglobulin light chain variable region"
     V_region        88..406
     V_segment       88..374
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66475.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       375..406
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           88 a          136 c          123 g           97 t
ORIGIN      
        1 tcagaagcag agctctgggg tgtctccacc atggcctgga ctcctctctg gctcaccctc
       61 ctcagtcttt gcacaggttc tatggtttct tctgagcaga ctcaggaccc tgcagtgtct
      121 gtggccttgg ggcagacagt caggattacc tgccaaggag acagcctcag aagctcttat
      181 gcaagctggt accaacagag gccaggccag gcccctgtgg tggtcgtcta tggtaacaag
      241 taccggccct cagggatccc agagcgattc tctggctcct actcccgaaa tacagcttcc
      301 ttgaccatca ctggggctca ggtggaagat gaggctgact attactgtga ctcctgggac
      361 agcaggggaa cccaattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct
      421 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000738             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:15141:18020
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000738
VERSION     KCWK01000738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15141:18020"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66476.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          163 c          122 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta tttctgccaa ctgtttgaca gtagtgttgt gttcttcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01000739             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:26951:8936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000739
VERSION     KCWK01000739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:26951:8936"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66477.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          161 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctata ctactactcc gactcagaca agcagctggg aactggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000740             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13772:5084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000740
VERSION     KCWK01000740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13772:5084"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..431
                     /note="immunoglobulin light chain variable region"
     V_region        104..431
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66478.1"
                     /translation="DYYCQVWDISTDHPVLF"
     J_segment       398..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          143 c          134 g          102 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac agcctctgcg gcctcctatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg gtcacctgtg gaggagagaa
      181 ccttggatat gaagttgtca actggtacca gcagaagcca ccgcaggccc ctgtggtggt
      241 catctatgct gattatgaac ggccctcagg gatccctaac cgattctctg gctccaaatc
      301 agggaatacg gccaccctga ccatcagcgg agtcgaggcc ggggatgagg ctgactatta
      361 ttgtcaggtg tgggacatta gtactgacca tccggtatta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000741             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:10319:11756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000741
VERSION     KCWK01000741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10319:11756"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66479.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       393..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>465
                     /gene="IGLC"
BASE COUNT           90 a          145 c          133 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gactctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgttaa ctggtaccag cagaagccac cgcaggcccc tgtcctggtc
      241 atctatgcta ataacgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt ggggcgttac tagtgatcat cccttattcg gaggagggac ccggctgacc
      421 gtccaaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000742             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:15100:14765
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000742
VERSION     KCWK01000742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15100:14765"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..268
                     /note="immunoglobulin light chain variable region"
     V_region        7..268
     V_segment       7..231
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <193..>240
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66480.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       232..268
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        269..>306
                     /gene="IGLC"
BASE COUNT           62 a           98 c           78 g           68 t
ORIGIN      
        1 acatggggaa gcagctccaa catcggaagt catagtgtct cctggtacca gcaactccca
       61 ggaacagctc ccaaactcct catctattat agtgatcaac gagcctcagg tgtctctgac
      121 cgattctctg gctcccagtc tggcacgtca gcctccctgg ccatcagtgg gctccagacc
      181 gaggatgagg ctgattatta ctgcgcggca tgggatgata gcctgagcgg ttacatcttc
      241 ggtgctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      301 ttcccg
//
LOCUS       KCWK01000743             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:7378:17735
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000743
VERSION     KCWK01000743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7378:17735"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66481.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          163 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcacc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000744             273 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:15658:10609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000744
VERSION     KCWK01000744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 273)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 273)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15658:10609"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..235
                     /note="immunoglobulin light chain variable region"
     V_region        116..235
     V_segment       116..199
                     /gene="IGLV2-118"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <163..>207
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66482.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       200..235
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        236..>273
                     /gene="IGLC"
BASE COUNT           44 a           93 c           76 g           60 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca ccatctctgg gctccagact gaggacgagg ctgattatta ttgttgctca
      181 tataggagtg gaaacacttg gctattcggc ggagggaccc ggctgaccgt cctaggtcag
      241 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000745             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:5064:18777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000745
VERSION     KCWK01000745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:5064:18777"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..313
                     /note="immunoglobulin light chain variable region"
     V_region        8..313
     V_segment       8..273
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <241..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66483.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       276..313
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>351
                     /gene="IGLC"
BASE COUNT           73 a          106 c           89 g           83 t
ORIGIN      
        1 acatgggctg gagcatcagc cagtctctca tgcaccttca gcggtggcat caatgttgct
       61 gactaccacg tacactggta tcagcagaag ccagggagtc ccccccgata tcttctgagg
      121 tacaaatcag actcagataa gggcctgggc tctggagtcc ccagccgctt ctctggatcc
      181 aatgcttcag cgaatacagg gattttacac atctctggtt tccagtctga ggatgaggct
      241 gactattact gtgccattgg ccacggcagc ggtgattaca tcttcggtac tgggacccgg
      301 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01000746             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:5812:19242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000746
VERSION     KCWK01000746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5812:19242"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66484.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       397..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           82 a          155 c          125 g          107 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcatctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagcattggc aacagctatg tgtactggtt ccagcagcgg ccgggcagcg tccccactat
      241 tgtgatttac aaagatgacc aaagaccctc tggggtccct gatcgattct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctgga ctgaagtctg gggacgaggc
      361 tgactattac tgtcagtctt ttgacagcag cagtgtctta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000747             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:10405:9994
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000747
VERSION     KCWK01000747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10405:9994"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66485.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           81 a          157 c          129 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accgtctcct gcactggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcagcact cagggacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tattgttgct catataggag tggaaacact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000748             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:14402:12472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000748
VERSION     KCWK01000748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14402:12472"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..406
                     /note="immunoglobulin light chain variable region"
     V_region        58..406
     V_segment       58..369
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66486.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       370..406
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           85 a          152 c          107 g          100 t
ORIGIN      
        1 acatggggga ctcctctcct cctcctgctc ctctctcact gcacaggttc cctctccaag
       61 cctatgctga ctcagccggc ctccctctca gcatctcctg gagcatcagc cagtctcaca
      121 tgcaccttca gcggtggcat caatgttgct gactaccaca cacactggta ccagcagaag
      181 ccagggagtc ccccccggta tcttctgaga tacagatcag actcagataa gggccagggc
      241 tctggagtcc ccagccggtt ctctggatcc aaagatgctg cagcgaacac agggatttta
      301 cgcatctctg ggctccagtc tgaggatgag gctgactatt actgtgccat tgggcacagc
      361 agcggtcctt acttcttcgg tgctgggacc cggctcaccg tcctaggtca gcccaaggct
      421 tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000749             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18304:14641
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000749
VERSION     KCWK01000749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18304:14641"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66487.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       415..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           93 a          162 c          126 g          107 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctc gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacacagccg ccctcagtgt ctggggcccc agggcagagg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag gttattatat atcctggtac cagcagctcc
      241 caggaacggc ccccaaactc ctcgtctatg acaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggttcct cagccaccct gaccatcact gggctccaga
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagtctgagt gctcgggtat
      421 tcggcggagg gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01000750             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:21559:16278
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000750
VERSION     KCWK01000750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21559:16278"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66488.1"
                     /translation="DYYCQVWDSSSEWVF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           91 a          143 c          136 g           92 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca gactctgcga cctcctatga gttgactcag
      121 gcaccctcag tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta aaactgtgca ctggtaccaa cagaaggcag cgcaggcccc tgtgctggtc
      241 atctttgctg atagcaaacg gccctcaggg atccctgacc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtgaatgg gttttcggcg gagggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000751             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:17785:18316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000751
VERSION     KCWK01000751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17785:18316"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..428
                     /note="immunoglobulin light chain variable region"
     V_region        105..428
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66489.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>467
                     /gene="IGLC"
BASE COUNT           87 a          141 c          136 g          103 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctatg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000752             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:26524:6201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000752
VERSION     KCWK01000752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:26524:6201"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66490.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          157 c          120 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcctagga
      241 acagctccca aactcctctt ttattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000753             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:10259:6460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000753
VERSION     KCWK01000753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:10259:6460"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..433
                     /note="immunoglobulin light chain variable region"
     V_region        85..433
     V_segment       85..396
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66491.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           94 a          158 c          113 g          106 t
ORIGIN      
        1 acatggggga aagaggctgt gtccaccatg gcctggactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctccaagcct atgctgactc agccggcctc cctctcagca
      121 tctcctggag catcagccag tctcaaatgc accttcagcg gtggcatcaa tgttgctgac
      181 taccacatac actggtacca gcagaagcca gggagtcccc cccgatatct tctgaggtac
      241 aaatcagact cagataaggg ccagggctct ggagtcccca gccgcttctc tggatccaaa
      301 gatgctgcag cgaacacagg gattttacgc atctctgggc tccagtctga ggatgaggct
      361 gactattact gtgccattgg acacagcagc ggtccttact tcttcggtgc tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01000754             497 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:15448:6960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000754
VERSION     KCWK01000754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 497)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 497)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..497
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:15448:6960"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..459
                     /note="immunoglobulin light chain variable region"
     V_region        126..459
     V_segment       126..422
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <390..>431
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66492.1"
                     /translation="DYYCQTWDTGIDVF"
     J_segment       423..459
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        460..>497
                     /gene="IGLC"
BASE COUNT           93 a          164 c          127 g          113 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggc cataatgagt gtctctgttt tcagggtctc
      121 tctcccagcc tgtgctgact cagtcgccct ctgcctctgc ctccctggga gcctcggtca
      181 agctcacctg cactctgagc agtgggcaca acagctacac catcgcatgg catcagcagc
      241 agcaagggaa ggcccctcgg tacttgatgt ggcttaaaag tgatggtagc cacagtaagg
      301 gggacgggat ccctgatcgc ttctcaggct ccagctccgg ggctgagcgc tacctcacca
      361 tctccaacct ccagtctgag gatgaggctg attattactg tcagacctgg gatactggca
      421 ttgatgtgtt cggaagcggc accaagttga ccgtcctcgg tcagcccaag gcttccccct
      481 tggtcactct gttcccg
//
LOCUS       KCWK01000755             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:4963:16435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000755
VERSION     KCWK01000755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4963:16435"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66493.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       391..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          136 c          139 g          100 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagg
      121 caccctcgat ttcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtgaac tggtaccagc agaaggcacc gcaggcccct gtgttggtca
      241 tgtatgctga tagcgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattatt
      361 gtcaggtgtg ggacatgaat agtcatcatc tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000756             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:10455:11346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000756
VERSION     KCWK01000756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10455:11346"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66494.1"
                     /translation="DYYCQVWDSTSDHVFF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          142 c          137 g           99 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccgccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacgac
      181 attggaagta aatatgtgca ctggtaccag cagaagccac cgcaggcccc tgtgctggtc
      241 atctattatg atggcgaacg gccctcaggg atccctgagc gattctctga ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtac tagtgatcat gtgtttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000757             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:19614:10932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000757
VERSION     KCWK01000757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19614:10932"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..423
                     /note="immunoglobulin light chain variable region"
     V_region        93..423
     V_segment       93..384
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66495.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       386..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           86 a          148 c          120 g          107 t
ORIGIN      
        1 acatggggga ggcagcactc aggacagtct ccagcatggc ctggtctcct ctcctcctca
       61 cccttctcat tcactgcaca gggtcctggg cccagtctgt gctgacgcag ccgccctcag
      121 tgtctggggc gcccgggcag agggtcacca tctcctgcac tgggagcagc tccaacattg
      181 gaggttatta tgtgcagtgg taccagcagc ttccaggaac ggcccccaaa ctcctcatct
      241 atgaaaatga taaacgaccc tcaggggttt ctgatcgatt ctctggctcc cagtctgatt
      301 cctcagcctc cctgaccatc actggactcc agtctgagga tgaggctgat tattactgcc
      361 agtcctatga cagcagcttg agtgttgtgt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000758             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17073:20123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000758
VERSION     KCWK01000758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17073:20123"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66496.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           88 a          141 c          117 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagccggcc aggatcacct gctctggaga tgtattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtatt ggtcatctct gaggacaccg
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gtagtggtca tggcttcttc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctaccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000759             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:10570:6337
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000759
VERSION     KCWK01000759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:10570:6337"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66497.1"
                     /translation="DYYCATWDDSLRGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           92 a          155 c          125 g          109 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaac agtgtcgcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatgatga tcaacgagcc tcgggtgtct ctgaccgatt
      301 ctctggctcc aggtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg ctacatggga tgatagcctg agaggttaca tcttcggtga
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01000760             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:14490:11440
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000760
VERSION     KCWK01000760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14490:11440"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66498.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          108 a          136 c          123 g           99 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg acctgacaca
      121 gccaccctca gtgtcagtgt ccccagggca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagaagtca ggccagggcc ctagactggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gtcaccttga ccatcagcgg ggcccagaca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagaa gtcctaatca tgtgtttttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000761             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:16806:10873
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000761
VERSION     KCWK01000761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16806:10873"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    60..390
                     /note="immunoglobulin light chain variable region"
     V_region        60..390
     V_segment       60..353
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <318..>362
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66499.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       354..390
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        391..>428
                     /gene="IGLC"
BASE COUNT           83 a          141 c          105 g           99 t
ORIGIN      
        1 acatggcctg ggatctgctc ctcttcaccc tcctcactca gggcacagga tcctgggctc
       61 aggctgccct gactcagcct ccctcaatgt ctgggtctcc tggacagtcg gtcaccatct
      121 cctacactgg aaccagcagt gacattggtg gttataaccg tgtctcctgg taccaacagc
      181 acccaggcaa agaccccaaa ttcatgattt atgaggtcag tcaacggccc tcaggggtct
      241 ctgatcgtat ctctggctcc aagtctggca acacggcctc cctgaccatc tctgggctcc
      301 agactgagga tgaggctggt tattactgca gctcatttgc aggtaccaac actggcttaa
      361 tcggtggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      421 tcttcccg
//
LOCUS       KCWK01000762             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:22623:12403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000762
VERSION     KCWK01000762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22623:12403"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66500.1"
                     /translation="DYYCSSYAGSNNFLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          155 c          117 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cactaatatt ggatattata atgctgtgtc ttggtaccaa caccatccag gcaaagcccc
      241 cagactcatg atttatgacg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacaatttt ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000763             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:14045:19304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000763
VERSION     KCWK01000763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:14045:19304"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..446
                     /note="immunoglobulin light chain variable region"
     V_region        98..446
     V_segment       98..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66501.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           90 a          162 c          120 g          112 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagtatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt ggtaaaaaca tgtactggta ccagcagaag ccagggcgcg ctcccaggtt
      241 tttcctgtac tacaactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcacgt atatgacagt agtactaatg tgttattcgg
      421 aggagggacc cgtctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01000764             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:21000:5859
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000764
VERSION     KCWK01000764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21000:5859"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66502.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          166 c          123 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgtcttt gctcatctct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000765             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:17556:5258
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000765
VERSION     KCWK01000765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17556:5258"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66503.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           83 a          163 c          122 g          100 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtggccac
      181 tacagctaca ccatcgcatg gcatcagcag cagcaaggga aggcccctcg gttcttgatg
      241 tggcttaaga gtgatggcag ccacaccaag ggggacgggg tccctgatcg cttctcaggc
      301 tccagctccg ggcctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatattggc atttgggtat tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000766             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:16161:12246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000766
VERSION     KCWK01000766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16161:12246"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66504.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          161 c          110 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccaa ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000767             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:27467:17141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000767
VERSION     KCWK01000767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:27467:17141"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..414
                     /note="immunoglobulin light chain variable region"
     V_region        86..414
     V_segment       86..370
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <342..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66505.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       384..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           85 a          146 c          114 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggctg ccccgactca gactccctct gtgtccgggt
      121 ctcctggaca gtcggtcacc atctcctgca ctggaaccag cagtgatatt gggtattatc
      181 atgctgtgtc ttggtaccag catcatccag gcaaagcccc caaactcatg atttatgagg
      241 tcaataaacg gcccgcaggg gtctctgatc gcttctctgg ctccaagtct ggcaacacgg
      301 cctccctgac catctctggg ctccagactg aggatgaggc tgattattac tgtagctcat
      361 atgcaggcag caacagttta ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000768             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:25970:14179
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000768
VERSION     KCWK01000768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:25970:14179"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66506.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          128 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgatcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000769             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:9197:10791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000769
VERSION     KCWK01000769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:9197:10791"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66507.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          143 c          132 g           92 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgaac tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa actgtgcact ggtaccagca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgat agtaaacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000770             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:14674:9566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000770
VERSION     KCWK01000770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14674:9566"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66508.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          150 c          138 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcccagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagctggctc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taactatgtg cactggtacc agcagaagcc agcgcaggcc cctgtagaga
      241 ttatctttgc tgataacaaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggatcac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 tctgtcaggt gtggggcagt cgtagtgatc atccggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000771             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:9035:12940
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000771
VERSION     KCWK01000771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9035:12940"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66509.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          147 c          130 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacgac cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000772             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:7929:6291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000772
VERSION     KCWK01000772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:7929:6291"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..262
                     /note="immunoglobulin light chain variable region"
     V_region        8..262
     V_segment       8..227
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>234
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66510.1"
                     /translation="DYYCSSYGGSNTLFF"
     J_segment       232..262
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        263..>300
                     /gene="IGLC"
BASE COUNT           63 a           87 c           77 g           73 t
ORIGIN      
        1 acatggggca gtgatattgg gtattatcat gctgtgtctt ggtaccagca tcatccaggc
       61 aaagccccca aactcatgat ttatgaggtc aataaacggc ccgcaggggt ctctgatcgc
      121 ttctctggct ccaagtctgg caacacggcc tccctgacca tctctgggct ccagactgag
      181 gatgaggctg attattactg cagctcatat ggaggcagca atactttatt cttcggagga
      241 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000773             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:17911:7024
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000773
VERSION     KCWK01000773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17911:7024"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66511.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       393..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>465
                     /gene="IGLC"
BASE COUNT           90 a          144 c          135 g           96 t
ORIGIN      
        1 acatgggggg gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gactctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgttaa ctggtaccag cagaagccac cgcaggcccc tgtcctggtc
      241 atctatgcta ataacgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt ggggcgttac tagtgatcat cccttattcg gaggagggac ccggctgacc
      421 gtccaaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000774             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:19776:13162
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000774
VERSION     KCWK01000774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19776:13162"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66512.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           93 a          156 c          127 g          108 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aacagtgtcg ccatctcctg
      181 ttctggaagc agctccaaca tcggaagtca tagtgtatcc tggtaccagc agctcccagg
      241 aacagctccc aaactcctca tctattatga tgatcaacga gcctcaggtg tctctgaccg
      301 attctctggc tccaggtctg gcacgtcagc ctccctggcc atcagtgggc tccagaccga
      361 ggatgaggct gattattact gcgcagcatg ggatgatagc ctgagaggtt acatcttcgg
      421 tgatgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01000775             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:7282:4441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000775
VERSION     KCWK01000775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:7282:4441"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66513.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       415..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          157 c          123 g          109 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg gttcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agcatctggg gcccccggac agagggtcac catctcctgc
      181 attagcagca gctccaacat cggggcggct tattatgtat cctggtacca acagttccca
      241 ggaacagccc ccaaactcct catctatgaa aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggtccctca gcctccctga ccatcactgg actccaatct
      361 gaggatgagg ctgattatta ctgtttagca tgggatacca gcctgaattg gatcttcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01000776             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:27184:14317
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000776
VERSION     KCWK01000776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:27184:14317"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66514.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          159 c          126 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga gcagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgcgaggtta catcttcggt
      421 catgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000777             284 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:8032:18281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000777
VERSION     KCWK01000777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 284)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8032:18281"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..246
                     /note="immunoglobulin light chain variable region"
     V_region        7..246
     V_segment       7..209
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <174..>218
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66515.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       210..246
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        247..>284
                     /gene="IGLC"
BASE COUNT           63 a           90 c           68 g           63 t
ORIGIN      
        1 acatggggta ccagcagaag ccagggagtc ccccccggta tcttctgact tacaaatcag
       61 actcagataa gggccagggc tctggagtcc ccagccactt ctctggatcc aaaaatgctt
      121 caacaaacac aggcatttta cacatctctg ggctccagtc tgaggatgag gctgactatt
      181 tctgtgccat tggacacagc agcggtcctt acatcttcgg tgctgggacc cggctcaccg
      241 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000778             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:16534:14326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000778
VERSION     KCWK01000778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16534:14326"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..439
                     /note="immunoglobulin light chain variable region"
     V_region        93..439
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66516.1"
                     /translation="DFFCAIGHSSGPYIF"
     J_segment       405..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>479
                     /gene="IGLC"
BASE COUNT           91 a          163 c          116 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacgtgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatccac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagtaacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcaacg aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctttttctgt gccattgggc acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtcctc ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000779             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:26053:9967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000779
VERSION     KCWK01000779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:26053:9967"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..456
                     /note="immunoglobulin light chain variable region"
     V_region        126..456
     V_segment       126..417
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66517.1"
                     /translation="DYYCQSYDSSLIVVLF"
     J_segment       419..456
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           93 a          155 c          129 g          117 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca cttcacagtt ccagggtcct
      121 gggcccagtc tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca
      181 ccatgtcctg cactgggagc agctccaaca ttggagatta ttttgtgcag tggtaccagc
      241 accttccagg aacggccccc aaactcctca tgtatgaaaa taataagcga ccctcaggga
      301 tttctgatcg attctctggc tcccagtctg gaacctcagc ctccctggcc atcactggac
      361 tccagtctga ggatgaggct gattattact gccagtccta tgacagcagt ttgattgttg
      421 tgttattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      481 tcactctctt cccg
//
LOCUS       KCWK01000780             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:9002:8743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000780
VERSION     KCWK01000780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9002:8743"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    27..357
                     /note="immunoglobulin light chain variable region"
     V_region        27..357
     V_segment       27..322
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <285..>329
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66518.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       324..357
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        358..>395
                     /gene="IGLC"
BASE COUNT           76 a          120 c          104 g           95 t
ORIGIN      
        1 acatgggggg cacaggatcc tgggttcagg ctgccccgac tcagcctccc tctgtgtccg
       61 ggtctcctgg acagtcggtc accatctcct gcactggaac cagcagtgat gttgggtatt
      121 ataacgctgt gtcttggtac caacagcatc caggcaaagc ccccaaactc atgatttatg
      181 acgtcattaa gcggccctca ggggtttctg atcgcttctc tggctccaag tctggcgaca
      241 cggcctccct gaccatctct gggctccagg ctgaggatga ggctgattat tactgcagct
      301 catatgcagg cagaaataat tttttattcg gaggagggac ccggctgacc gtcctaggtc
      361 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000781             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:26168:6418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000781
VERSION     KCWK01000781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:26168:6418"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66519.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       399..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          157 c          122 g          105 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaagtcatg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat atacaggcat caacagttac atcttcggtg gtgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01000782             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:5476:14544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000782
VERSION     KCWK01000782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5476:14544"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66520.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          163 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca aacagctggg gcctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000783             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:12678:13786
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000783
VERSION     KCWK01000783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12678:13786"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66521.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       399..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           95 a          150 c          114 g          115 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcgcag cctgtgctga ctcagccaac ctccctctca
      121 gcatctcctg gagcatcagc cagactcacc tgcaccttga gcagtggctt cagtattggt
      181 aattacagga tattctggta ccagcagaag ccagggagtc ctccccggta tcttctgagc
      241 taccacacag actcagatat gcaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgttt cggccaatgc agggatttta ctcatctctg gactccagtc tgaggatgag
      361 gctgactatt actgtatgat ttggcacaac aatgcttatt gggtattcgg cggagggacc
      421 cggctaaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000784             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11514:2358
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000784
VERSION     KCWK01000784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11514:2358"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..390
                     /note="immunoglobulin light chain variable region"
     V_region        63..390
     V_segment       63..350
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <312..>362
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66522.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       354..390
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        391..>428
                     /gene="IGLC"
BASE COUNT           82 a          129 c          121 g           96 t
ORIGIN      
        1 acatgggggc ctggactttt ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg
       61 cctcctatga tctgactcag ccaccctcgg tgtcagtgtc cccaggacag acggccagga
      121 tcacctgtgg aggagacaac attggaagtg aagttgtcaa ctggtaccag cagaggccac
      181 cgcaggcccc tgtgctggtc atctatgctg attatgaacg gccctcaggg atccctgagc
      241 gattctctgg ctccaaatca gggaacacgg ccaccctgac catcagtgga gtcgaggccg
      301 gggatgaggc tgactattat tgtcaggtgt gggacattta tattgaccat ccggtgttat
      361 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      421 tcttcccg
//
LOCUS       KCWK01000785             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:17886:11047
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000785
VERSION     KCWK01000785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17886:11047"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..343
                     /note="immunoglobulin light chain variable region"
     V_region        13..343
     V_segment       13..308
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66523.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       313..343
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>381
                     /gene="IGLC"
BASE COUNT           75 a          120 c           97 g           89 t
ORIGIN      
        1 acatgggggg ctcaggctgc cccgactcag actccctctg tgtccgggtc tcctggacag
       61 tcggtcacca tctcctgcac tggaaccagc agtgatattg ggtattatca tgctgtgtct
      121 tggtaccagc atcatccagg caaagccccc aaactcatga tttatgaggt caataaacgg
      181 cccgcagggg tctctgatcg cttctctggc tccaagtctg gcaacacggc ctccctgacc
      241 atctctgggc tccagactga ggatgaggct gattattact gcagctcata tgcaggcagc
      301 aacactttat tcttcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      361 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000786             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:7258:14816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000786
VERSION     KCWK01000786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7258:14816"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66524.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       411..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          157 c          117 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttggtgtcta ccacatacac tggtaccaac tgaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tccttatatt ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000787             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:15548:18766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000787
VERSION     KCWK01000787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15548:18766"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..444
                     /note="immunoglobulin light chain variable region"
     V_region        96..444
     V_segment       96..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66525.1"
                     /translation="DYYCHVYDNSTNVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          163 c          116 g          112 t
ORIGIN      
        1 acatggggtc tgtggcctca gaggtagccg tgtccaccat ggccctgact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcccagcc tatgctgact cagccaccct
      121 ccctgtctgc atccccggga gcatcggcca gactcccctg caccctgagc agtgacctca
      181 gtgttggtgg taaaaacatt tactggtacc agcagaagcc agggcgcgct cccaggtttt
      241 tcctgtacta caactccgac tcagacaagc agctgggacc tggggtcccc aatcgcgtct
      301 ctggctccaa ggagacctca agtaacacag cgtttttgct catctctggg ctccagcctg
      361 aggacgaggc cgattattac tgtcacgtat atgacaatag tactaatgtg ttattcggag
      421 gagggacccg tgtgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000788             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:12195:17932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000788
VERSION     KCWK01000788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12195:17932"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66526.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          163 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000789             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:13399:17191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000789
VERSION     KCWK01000789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13399:17191"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66527.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          143 c          136 g          100 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcga tttcagtgtc cccaggacag acggccaggg tcacctgtgg gggagacaac
      181 atcggaggtg aagttgtgaa ttggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atctatgctg atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacgcgg ccaccctgac catcagcggg gtcgaggccg gagatgaggc tgactattac
      361 tgtcaggtgt gggaccttaa tagtcatcat ctcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000790             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:23427:14020
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000790
VERSION     KCWK01000790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23427:14020"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..442
                     /note="immunoglobulin light chain variable region"
     V_region        115..442
     V_segment       115..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66528.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           88 a          154 c          127 g          111 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtcttct ggaagcagct cccaggaaca
      241 gctcccaaac tcctcatcta ttatagtgat caacgagcct caggtgtctc tgaccgattc
      301 tctggctctc agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat
      361 gaggctgatt attactgcgc agcatgggat gatagcctga gcggttacat cttcggtgtt
      421 gggacccggc tcgccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01000791             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:15836:13271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000791
VERSION     KCWK01000791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15836:13271"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..387
                     /note="immunoglobulin light chain variable region"
     V_region        99..387
     V_segment       99..350
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <318..>359
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66529.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       351..387
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        388..>425
                     /gene="IGLC"
BASE COUNT           75 a          142 c          107 g          101 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagag gccagggagc gctcccaggt
      241 tattcctgta ttactactcc gactcaggta acacagcgtt tttgctcatc tctggactcc
      301 agcctgagga cgaggccgat tattactgtc aggtgtatga cagtagtgct gtgttattcg
      361 gaggagggac ccgactgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      421 tcccg
//
LOCUS       KCWK01000792             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:25668:14857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000792
VERSION     KCWK01000792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25668:14857"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..297
                     /note="immunoglobulin light chain variable region"
     V_region        8..297
     V_segment       8..259
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66530.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       261..297
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>335
                     /gene="IGLC"
BASE COUNT           73 a          102 c           96 g           64 t
ORIGIN      
        1 acatggggtc cccaggacag acggccagga tcacctgtgg gggagacaac attggaagtc
       61 aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc atcttttatt
      121 ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca gggaacaccg
      181 ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac tgtcaggtgt
      241 gggacacaag tcttgatcac ggcttattcg gaggagggac ccggctgacc gtcctaggtc
      301 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000793             375 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:3534:13063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000793
VERSION     KCWK01000793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 375)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:3534:13063"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..337
                     /note="immunoglobulin light chain variable region"
     V_region        8..337
     V_segment       8..298
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <265..>309
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66531.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       300..337
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        338..>375
                     /gene="IGLC"
BASE COUNT           82 a          114 c           87 g           92 t
ORIGIN      
        1 acatgggcaa cctccctctc agcatctcct ggagcatcag ccagactcac ctgcaccttg
       61 aacagtggca tcagtgttgc taattacagg atattctggt accaccagaa gccagggagt
      121 cctccccggt atcttctgaa ctaccacaca gactcagata ttcatcaggg ctctggagtc
      181 cccagccgct tctctggatc caaagatgct tcggccaatg cagggatttt actcatctct
      241 ggactccagt ctgaggatga ggctgactat tactgtatga tttggcacaa caatgcttat
      301 tgggttttcg gcggagggac ccggctaacc gtcctaggtc agcccaaggc tgccccctcg
      361 gtcactctct tcccg
//
LOCUS       KCWK01000794             410 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:17978:12460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000794
VERSION     KCWK01000794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 410)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17978:12460"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    48..372
                     /note="immunoglobulin light chain variable region"
     V_region        48..372
     V_segment       48..334
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <297..>344
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66532.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       335..372
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        373..>410
                     /gene="IGLC"
BASE COUNT           82 a          119 c          123 g           86 t
ORIGIN      
        1 acatggggct cctcggcctc cttgctcact ttacaggctc tgcggcctcc tatgaggtga
       61 ctcagccacg ctcagtgtcc gtgtccccag gacagacggc caggatcacc tgtgggggag
      121 acaacattgg aagtaaaagt gtgcagtggt accagcagac gccaccgcag gcccctgtac
      181 tggtcattta tggtgatagg gaacggccct cagggatccc tgagcgattc tctggttcca
      241 actcagggaa caccgccacc ctgaccatca gcggggtcga ggccggggat gaggctgact
      301 attactgtca ggtgtgggat agtagtagta aatatgtgtt attcggagga gggacccggc
      361 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000795             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:25279:12488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000795
VERSION     KCWK01000795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25279:12488"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66533.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           86 a          153 c          123 g          107 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtctccatc tcctgttctg gaagcagctc
      181 caacatcgga agtcatagtg tctcctggta ccagcagctc ccaggaacag ctcccaaact
      241 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctctca
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag gccgaggatg aggctgatta
      361 ttactgcgca gcatgggatg atagtctgag cggttacatc ttcggtgctg ggacccggct
      421 cgccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000796             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10617:9933
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000796
VERSION     KCWK01000796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10617:9933"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..303
                     /note="immunoglobulin light chain variable region"
     V_region        5..303
     V_segment       5..266
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <222..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66534.1"
                     /translation="DYFCAAACGSGSSWQWVF"
     J_segment       267..303
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           71 a          102 c          101 g           67 t
ORIGIN      
        1 acatggggtc cccaggacag acagccagca tcacctgctc tggaaataaa ttggggaatg
       61 tatatgctta ctggttccag cagaagccag gccaggcccc tgtagtggtc atctacaaag
      121 ataccaaccg gccctcaggg atccctgagc gattctctgg ctccgactca gggaacacgg
      181 ccaccctgac catcagcagg gtcgaggctg gggatgaggc cgactatttt tgtgctgcag
      241 cctgtggcag tggcagcagc tggcagtggg tattcggcgg agggacccgg ctaatcgtcc
      301 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000797             378 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:6856:18716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000797
VERSION     KCWK01000797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 378)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 378)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:6856:18716"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..340
                     /note="immunoglobulin light chain variable region"
     V_region        8..340
     V_segment       8..303
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <268..>312
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66535.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       306..340
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        341..>378
                     /gene="IGLC"
BASE COUNT           79 a          120 c           97 g           82 t
ORIGIN      
        1 acatgggagc caccctccct gtctgcatcc ccgggagcat cggccagact cccctgcacc
       61 ctgagcagtg acctcagtgt tggtagtaaa aacatgtact ggtaccagca gaagccaggg
      121 agcgctccca cgttattcct gtactactac tccgactcag acaagcagtt gggacctggg
      181 gtccccaatc gagtctctgg ctccaaggag acctcaacta acacagcgtt tttgctcatc
      241 tctgggctcc agcctgagga cgaggccgat tattactgtc aggtgtatga cagcagtgct
      301 aatgtcttat tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc
      361 tcggtcactc tcttcccg
//
LOCUS       KCWK01000798             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18199:13533
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000798
VERSION     KCWK01000798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18199:13533"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..456
                     /note="immunoglobulin light chain variable region"
     V_region        126..456
     V_segment       126..419
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66536.1"
                     /translation="DYYCAAWDDSLTGYIF"
     J_segment       420..456
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           94 a          158 c          129 g          113 t
ORIGIN      
        1 acatgggggg gggtgaagcg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa
       61 tctccagcat ggcctggttc cctctcctcc tcaccctcct cactcactgt gcagggtcct
      121 gggcccagtc tgtgctgact cagcctccct cagcgtctga ggccgccagg aacagtgtca
      181 ccatctcctg ttctggaagc agctccaaca tcggaagtaa tagtgtttcc tggtaccagc
      241 agctcccaga aacggctccc aaactcctca tctattataa tgatcggcga gcctcaggtg
      301 tctctgaccg attctctggc tccaagtctg gcacgtcagc ctccctggcc atcagtgggc
      361 tccagaccga ggatgaggct gattattact gcgctgcatg ggatgatagc ctgaccggtt
      421 acatattcgg ttttgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg
      481 tcactctgtt cccg
//
LOCUS       KCWK01000799             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:21464:15067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000799
VERSION     KCWK01000799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21464:15067"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66537.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           88 a          161 c          117 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag tcggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttggtgtcta ccacatccac tggtaccagc tgaagccagg gagtcccccc cggtttcttc
      241 tgcggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tccttacatc ttcggtcctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000800             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:15699:24624
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000800
VERSION     KCWK01000800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15699:24624"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66538.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          148 c          130 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcgc atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000801             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:11029:20494
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000801
VERSION     KCWK01000801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11029:20494"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66539.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           92 a          164 c          122 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccgactgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000802             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18218:3094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000802
VERSION     KCWK01000802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18218:3094"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66540.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          162 c          123 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg accgggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000803             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:7174:16913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000803
VERSION     KCWK01000803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7174:16913"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66541.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          157 c          117 g          110 t
ORIGIN      
        1 acatggggtc tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cgatatcttc
      241 tgagatacaa atcggactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000804             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:7273:13061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000804
VERSION     KCWK01000804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:7273:13061"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66542.1"
                     /translation="DYYCAVWDDRLTGYVF"
     J_segment       397..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          153 c          117 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagca atagtgtatc ctggtaccag caactcccag aaacggctcc caaactcctc
      241 atctattata atgatcggcg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagtat gggatgatcg cctgaccggt tacgtattcg gtgttgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000805             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:7802:5212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000805
VERSION     KCWK01000805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:7802:5212"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..403
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66543.1"
                     /translation="DYYCASYEGSNTFLF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          159 c          121 g          106 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcagtggaac
      181 cagcactaag attgggtatc acaatgctgt gtcctggtac caagagcatc caggcaaagc
      241 ccccaaactc atgatttatg acgtcaataa gcggcccaca gggatctctg atcgcttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccagg ctgatgatga
      361 ggctgattat tactgcgcct catatgaagg cagcaatact ttcctcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000806             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:20378:6146
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000806
VERSION     KCWK01000806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20378:6146"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..262
                     /note="immunoglobulin light chain variable region"
     V_region        5..262
     V_segment       5..224
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <187..>234
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66544.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       226..262
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        263..>300
                     /gene="IGLC"
BASE COUNT           67 a           91 c           82 g           60 t
ORIGIN      
        1 acatggggag acaacattgg aagtcaaagt gtgcactggt accagcacaa gccaccgcag
       61 gcccctgtac tggtcatctt ttattatacc gaacggccct caggaatccc tgagcgattc
      121 tctggctcca aatcagggaa caccgccacc ctgaccatca gcggggtcga ggccggggat
      181 gaggctgact attactgtca ggtgtgggac acaactattg atcacggctt attcggagga
      241 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000807             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17258:2224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000807
VERSION     KCWK01000807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17258:2224"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66545.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          129 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 aaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000808             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:12900:18995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000808
VERSION     KCWK01000808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12900:18995"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66546.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           92 a          156 c          124 g          114 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cacttcacag ttccagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggagat tattttgtgc agtggtacca gcaccttcca
      241 ggaacggccc ccaaactcct catctatgaa aataataagc gaccctcagg gatttctgat
      301 cgattctctg gctcccagtc tggaacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtttgattgc tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01000809             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:6848:6568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000809
VERSION     KCWK01000809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6848:6568"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66547.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          145 c          141 g           93 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatca tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attggaagtg aggttgtgaa ctggtaccag cagaagccag cgcaggcccc tgtgctggtc
      241 atctatgctg atagcgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg ggggtgaggc tgactattac
      361 tgtcaggtgt gggacatgcg tagtgatcaa ccgctattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000810             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:15213:22062
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000810
VERSION     KCWK01000810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15213:22062"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66548.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          163 c          119 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcccgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatattgg caataaaaac atgtactggt accagcagaa gccagggagc gctcccaagt
      241 tattcctgta ctactactcc gactcagaca tgcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000811             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:25010:9996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000811
VERSION     KCWK01000811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25010:9996"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66549.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          159 c          114 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccatcctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagtagc ggcatcaatg
      181 ttggttcgta cagtattttc tggtaccaac agaagccagg gagtcctccc cggtaccttc
      241 tgtactactc ctcagactca attaagcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcaggac ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc atagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000812             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:13054:5986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000812
VERSION     KCWK01000812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13054:5986"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..433
                     /note="immunoglobulin light chain variable region"
     V_region        88..433
     V_segment       88..396
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66550.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           91 a          159 c          111 g          110 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttga gcagtggcaa tgttggtagt
      181 tacagcatat tctggtacca gcagaagcca gggagtcctc cccggtacct tctttactac
      241 tactcagact caagtaacca ccaggactct ggagtccccg gccgcttctc tggatcgaaa
      301 gatgcttcag ccaatgcagg gcttttactg atctctgggc tccagtctga agatgaggct
      361 gactattact gtgccacatg gcacagcagc gcttcttaca tcttcggtgc tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01000813             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:4880:10895
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000813
VERSION     KCWK01000813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:4880:10895"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66551.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          130 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct caaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000814             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:13344:7210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000814
VERSION     KCWK01000814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13344:7210"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66552.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtaa ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000815             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:14235:11618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000815
VERSION     KCWK01000815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14235:11618"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66553.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          152 c          120 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaacagtgtc gccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattatg atgatcaacg agcctcgggt gtctctgacc gattctctgg ctccaggtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagaggt tacatcttcg gtgatgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000816             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:16870:17384
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000816
VERSION     KCWK01000816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16870:17384"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66554.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          161 c          119 g          106 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca actgcacctt gagcagtggc gtcaatgtgg
      181 gtagtcacag catattctgg taccagcaga agccagggag tcctccccgg taccttctgt
      241 actaccagtc agactcaagg aagcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggctgt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc ctatggcaca gcagcgcttc ttgcatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000817             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:14695:10063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000817
VERSION     KCWK01000817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14695:10063"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..440
                     /note="immunoglobulin light chain variable region"
     V_region        99..440
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66555.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>481
                     /gene="IGLC"
BASE COUNT           90 a          161 c          120 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01000818             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:21653:8756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000818
VERSION     KCWK01000818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21653:8756"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..403
                     /note="immunoglobulin light chain variable region"
     V_region        58..403
     V_segment       58..366
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66556.1"
                     /translation="DYYCAIGHSSGYYIF"
     J_segment       369..403
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        404..>444
                     /gene="IGLC"
BASE COUNT           87 a          150 c          104 g          103 t
ORIGIN      
        1 acatggggga ctcctctcct cctcctgctc ctctctcact gcacaggttc cctctccaaa
       61 cctttgctga ctcagccggc ctccctctca gcatctcctg gagcatcagc cagtctcaca
      121 tgcaccttca gcggtggcat caatgttgct ggctaccata tacactggta ccagcagaag
      181 ccagggagtc ctccccggta tcttctgaga tacaaatcag actcagatca gggccagggc
      241 tctggagtcc ccagccgctt ctctggatcc aaagatgctt cagcgaacac agggatttta
      301 cgcatctctg ggctccagtc tgaggatgag gctgactatt actgtgccat tgggcacagc
      361 agcggttatt acatattcgg tgccgggacc cggctcaccg tcccaggtca gcccaaggct
      421 tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000819             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:20299:18771
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000819
VERSION     KCWK01000819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20299:18771"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66557.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       398..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           85 a          158 c          118 g          112 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgcc ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaagct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtcttat aatgctgtgt cttggtacca acagcgtcca ggcaaagccc
      241 cccaactcat agtttttgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaactc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgctgctca tatgtaggca gcaacactta catcttcgat gttgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000820             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:19597:4472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000820
VERSION     KCWK01000820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:19597:4472"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66558.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          154 c          118 g          110 t
ORIGIN      
        1 acatgggtgg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca gtggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcgtccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaagc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcggac gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000821             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:10139:16099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000821
VERSION     KCWK01000821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10139:16099"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66559.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          163 c          118 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagcgacc
      181 tcaatattgg caataaaaac atgtactggt accagcagaa gccagggagc gctcccaagt
      241 tattcctata ctactactcc gactcagaca tgcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000822             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:5710:13227
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000822
VERSION     KCWK01000822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5710:13227"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66560.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          157 c          119 g          111 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgtctacca cgtacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggggt ccccagccgc ttctctggat
      301 ccagtaatgc ttcagcgaac acagggattt tacgcatttc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtct ttacatcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000823             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:17569:15448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000823
VERSION     KCWK01000823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17569:15448"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66561.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           93 a          161 c          107 g          113 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttta gcagtggcat caatgttggt
      181 agttacagca tattctggta ccaacagaag ccagggagtc ctccccggta ccttctctac
      241 tactactcag actcaagtaa acaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cggccaatgc aggcctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccat atggcacagc agcgcttctt acttcttcgg tactgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000824             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:8913:5142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000824
VERSION     KCWK01000824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8913:5142"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66562.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           92 a          158 c          121 g          110 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccggcacc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgataacctg agcggttaca tcttcggttc
      421 tgggacccga ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01000825             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:22223:7797
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000825
VERSION     KCWK01000825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22223:7797"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66563.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       399..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           96 a          150 c          112 g          116 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcgcag cctgtgctga ctcagccaac ctccctctca
      121 gcatctcctg gagcatcagc cagactcacc tgcaccttga acagtggcat cagtgttggt
      181 aattacagga tattctggta ccaccagaag ccagggagtc ctccccggta tcttctgaac
      241 taccacacag actcagatat tcatcagggg tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cggccaatgc agggatttta ctcatctctg gactccagtc tgaggatgag
      361 gctgactatt actgtatgat ttggcacaac aatgcttatt gggttttcgg cggagggacc
      421 cggctaaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000826             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:18418:4925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000826
VERSION     KCWK01000826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18418:4925"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66564.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          147 c          129 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaataccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000827             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:19931:10497
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000827
VERSION     KCWK01000827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19931:10497"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..423
                     /note="immunoglobulin light chain variable region"
     V_region        93..423
     V_segment       93..386
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66565.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       388..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           88 a          154 c          117 g          102 t
ORIGIN      
        1 acatggggga ggcagcactc aggacagtct ccagcatggc ctcgtctcct ctcctcctca
       61 cccttttcat tcactgcaca gggtcctggg cccagtctgt gctgacacag ccgccctcag
      121 tgtctggggc cccagggcag agggtcacca tctcctgcac tgggagcagc tccaacattg
      181 gaggttatta tatatcctgg taccagcagc tcccaggaac ggcccccaaa ctcctcgtct
      241 atgacaataa taagcgaccc tcaggggttt ctgaccgatt ctctggctcc aagtctggtt
      301 cctcagccac cctgaccatc actgggctcc agactgagga tgaggctgat tattactgcc
      361 agtcctatga cagcagtctg agtgctcggg tattcggcgg agggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000828             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:11726:14389
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000828
VERSION     KCWK01000828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11726:14389"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66566.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       385..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           97 a          142 c          121 g           98 t
ORIGIN      
        1 atgggggtgg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gaagaattgc
      181 caaaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtc cagatcatct
      241 atgaggacag taaacggccc tctgggatcc ctgagagaat ctctggctcc agctcaggga
      301 cagtggccac cttgactatc actggggccc aggtggagga tgaagctgac tactactgtt
      361 tctcaacaga caccagtggt aatcgggtat tcggcggagg gacccgtcta accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000829             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:4359:15743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000829
VERSION     KCWK01000829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4359:15743"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66567.1"
                     /translation="DYFGQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          162 c          124 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttcggccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000830             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:22900:15155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000830
VERSION     KCWK01000830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22900:15155"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66568.1"
                     /translation="DYYCHVYDSSSNVLF"
     J_segment       414..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcgtcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctcc gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtagtaat gtattattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000831             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:13517:15449
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000831
VERSION     KCWK01000831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13517:15449"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66569.1"
                     /translation="DYYCQSSHSRVNHPFF"
     J_segment       395..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          103 a          136 c          123 g          101 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagacctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaacact
      181 ggcaaaaaaa tatgctcagt ggttccagca gaagccaggc caggcccctg tgttggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacagtt accttgacca tcagtggggc ccaggtagaa gatgaggctg actattactg
      361 tcaatcatcg cacagcaggg ttaatcatcc gtttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000832             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:13541:9229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000832
VERSION     KCWK01000832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13541:9229"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66570.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          144 c          139 g           93 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttggaagtga agttgtgaac tggtaccagc agaagccagc gcacgcccct gtgctggtca
      241 tctatgctaa tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg gggtgaggct gactattact
      361 gtcaggtgtg ggacatgcgt agtgatcaac cgctattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000833             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:23068:12450
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000833
VERSION     KCWK01000833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:23068:12450"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66571.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          143 c          132 g           93 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgaa ttgactcagt
      121 caccctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa aactgtgcac tggtaccaac agaagccacc gcagggccct ctattggtca
      241 tctttgctga tagtagacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000834             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:19685:18068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000834
VERSION     KCWK01000834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19685:18068"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66572.1"
                     /translation="DYYCQSYDSSLSGVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          155 c          128 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcagtgggag caactccaac attggatact attatgtgca gtggtaccag cagcttccag
      241 ggacggcccc caaactcctc atctatgaaa ataataagcg accctctggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag tttgagtggt gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000835             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:22053:19644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000835
VERSION     KCWK01000835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:22053:19644"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..418
                     /note="immunoglobulin light chain variable region"
     V_region        101..418
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66573.1"
                     /translation="DYYCYSSDSNSEWLF"
     J_segment       390..418
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>460
                     /gene="IGLC"
BASE COUNT           97 a          141 c          124 g           98 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatagcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgaga tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttcccgca gaaggcaggc cagcccccta tggtgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttactcatca gacagcaata gtgaatggct attcgacgga gggacccggc tgaccgtcgt
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000836             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:6363:11179
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000836
VERSION     KCWK01000836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6363:11179"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..393
                     /note="immunoglobulin light chain variable region"
     V_region        63..393
     V_segment       63..349
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <321..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66574.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       363..393
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>431
                     /gene="IGLC"
BASE COUNT           81 a          139 c          109 g          102 t
ORIGIN      
        1 acatgggggt ctgggctctg ctcctcctca ccctcctcac tcagggcaca ggatcctggg
       61 ctcaggctgc cccgactcag actccctctg tgtccgggtc tcctggacag tcggtcacca
      121 tctcctgcac tggaaccagc agtgatattg ggtattatca tgctgtgtct tggtaccagc
      181 atcatccagg caaagccccc aaactcatga tttatgaggt caataaacgg cccgcagggg
      241 tctctgatcg cttctctggc tccaagtctg gcaacacggc ctccctgacc atctctgggc
      301 tccagactga ggatgaggct gattattact gtagctcata tgcaggcagc aacagtttat
      361 tcttcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      421 ctctcttccc g
//
LOCUS       KCWK01000837             310 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:25217:9241
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000837
VERSION     KCWK01000837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 310)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:25217:9241"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..272
                     /note="immunoglobulin light chain variable region"
     V_region        8..272
     V_segment       8..235
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <197..>244
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66575.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       236..272
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        273..>310
                     /gene="IGLC"
BASE COUNT           67 a           89 c           89 g           65 t
ORIGIN      
        1 acatgggacc tgtgggggag acaacattgg aattaaattt gtccactggt accagcagaa
       61 gccagcgcag gcccctgtga aggtcatcta tgctgatgac aaacggccct cagggatccc
      121 tgagagattc tctggctcca attcagggaa caccgccacc ctgaccatca gcggggtcga
      181 ggccggggat gaggctgact attcctgtca ggtgtgggac agtgagactg atcattacat
      241 cttcggtgtt gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac
      301 tctgttcccg
//
LOCUS       KCWK01000838             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:9838:20289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000838
VERSION     KCWK01000838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:9838:20289"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66576.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           92 a          160 c          114 g          107 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca ggccttttac ggatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggg ggggggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000839             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:11303:18391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000839
VERSION     KCWK01000839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11303:18391"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66577.1"
                     /translation="DYHCQVYDSSANVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          163 c          124 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtccg ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagtagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctccccgg
      241 ttattcctgt tctactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaaataac acagcgtttt tgctcatctc tggcctccag
      361 cctgaggacg aggccgatta tcactgtcag gtgtatgaca gtagtgcaaa tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01000840             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:22794:10482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000840
VERSION     KCWK01000840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22794:10482"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66578.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          158 c          124 g          111 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtggtgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcactctgag tagtgacctc
      181 agtgttggtg gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgttct accagtccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg actccagcct
      361 gaggacgagg ccgattatta ctgtcaggtg tatgacagta gtgcaaatgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01000841             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:13471:10555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000841
VERSION     KCWK01000841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13471:10555"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..419
                     /note="immunoglobulin light chain variable region"
     V_region        89..419
     V_segment       89..384
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66579.1"
                     /translation="DYYCSSYAGSNSLVF"
     J_segment       389..419
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           87 a          149 c          115 g          106 t
ORIGIN      
        1 acatgggggg cactctcggg acatctccac catggcctgg gatctgctcc tcttcaccct
       61 cctcactcag ggcacaggat cctgggctca ggctgtcctg actcagcctc cctcaatgtc
      121 tgggtctcct ggacagtcgg tcaccatctc ctgcactgga accagcagtg acattggtag
      181 ttataaccgt gtctcctggt accaacatca cccagacaaa gcccccaaag tcatgattta
      241 tgagggtagt cagcggccct caggggtctc tgatcgcttc tctgcctcca agtctggcaa
      301 aacggcctcc ctgaccatct ctgggctcca ggctgaggat gaggctgatt attactgcag
      361 ctcatatgca ggcagcaata gtttggtttt cggcggaggg acccggctaa ccgtcctagg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000842             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:8024:14341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000842
VERSION     KCWK01000842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8024:14341"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66580.1"
                     /translation="DYYCSSYAGSNTHWLF"
     J_segment       410..440
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           88 a          159 c          121 g          110 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac cagctacacc caggcaaagc
      241 ccccaaactc atgatttatg atgtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctgacaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 gactgattat tactgcagct catatgcagg cagcaacact cattggcttt tcggcggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000843             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:17163:8360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000843
VERSION     KCWK01000843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17163:8360"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66581.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           90 a          156 c          118 g          109 t
ORIGIN      
        1 acatggggtg ggatctcacg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tatgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc cggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt attcttcggg ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000844             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:12562:19559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000844
VERSION     KCWK01000844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12562:19559"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..237
                     /note="immunoglobulin light chain variable region"
     V_region        8..237
     V_segment       8..197
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <165..>209
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66582.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       200..237
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>275
                     /gene="IGLC"
BASE COUNT           58 a           82 c           74 g           61 t
ORIGIN      
        1 acatggggaa gccagggagt cctccccgat atcttctgag atacaaatcg gactcagata
       61 agggccaggg ctctggagtc cccagccgct tctctggatc caaagatgct tcagcgaaca
      121 cagggatttt acgcatctct gggctccagt ctgaggatga ggctgactat tactgtgcca
      181 ttggacacag cagcggtgat tacatcttcg gtgctgggac ccggctcacc gtcctaggtc
      241 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000845             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:8973:10943
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000845
VERSION     KCWK01000845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8973:10943"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..430
                     /note="immunoglobulin light chain variable region"
     V_region        85..430
     V_segment       85..391
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66583.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       393..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          159 c          116 g          107 t
ORIGIN      
        1 acatggggag aggtagccgt gtccaccatg gccctgactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctcccagcct gtgctgactc agccaccctc cctgtctgca
      121 tccccgggag catcggccag actcccctgc accctgagca gtgacctcag tgttggtagt
      181 aaaaacatgt actggtacca gcagaagcca gggagcgctc ccaggttatt cctgtactac
      241 tactccgact cagacaacca gctgggacct ggggtcccca atcgagtctc tggctccaag
      301 gagacctcaa gtaacacagc gtttttgctc atctctgggc tccagcctga ggacgaggcc
      361 gattatttct gccaggtgtt tgacagtagt gttgtgttct tcggaggagg gacccgactg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000846             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:7955:4721
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000846
VERSION     KCWK01000846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7955:4721"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66584.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          153 c          127 g          115 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc acgatctcct
      181 gcagtgggag caactccaac attggatatt attatgtgca gtggtaccag cagcttccag
      241 gaacggcctc caaactcctc atctatgaaa ataataagcg accctctggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccactcct atgacagcag tttgagtggt gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000847             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:17688:9774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000847
VERSION     KCWK01000847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17688:9774"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66585.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          149 c          116 g          109 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgttcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000848             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:9305:12205
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000848
VERSION     KCWK01000848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9305:12205"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66586.1"
                     /translation="DYYCSSYAGSNTHWLF"
     J_segment       410..440
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           88 a          159 c          121 g          110 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac cagctacacc caggcaaagc
      241 ccccaaactc atgatttatg atgtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctgacaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 gactgattat tactgcagct catatgcagg cagcaacact cattggcttt tcggcggagg
      421 gacccggctg actgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000849             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:16423:16800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000849
VERSION     KCWK01000849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16423:16800"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..397
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66587.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       402..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           89 a          151 c          120 g          110 t
ORIGIN      
        1 acatggggga tctcaggagg cagcgctctc aggacttctc caccatggtc tgggctctgc
       61 tcctcctcac cctcctcact cagggcacag gatcctgggc tcaggctgcc ccgactcaga
      121 ctccctctgt gtccgggtct cctggacagt cggtcaccat ctcctgcact ggaaccagca
      181 gtgatattgg gtattatcat gctgtgtctt ggtaccagca tcatccaggc aaagccccca
      241 aactcatgat ttatgaggtc aataaacggc ccgcaggggt ctctgatcgc ttctctggct
      301 ccaagtctgg caacacggcc tccctgacca tctctgggct ccagactgag gatgaggctg
      361 attattactg cagctcatat ggaggcagca atagtttatt cttcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000850             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:20529:6320
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000850
VERSION     KCWK01000850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20529:6320"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66588.1"
                     /translation="DYYCQSADSSPNHVFF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          110 a          134 c          120 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg acctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actgaaaaaa aaatatactc agtggttcca gcagaagcca ggccaggccc ctatagtggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccagaca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagta gtcctaatca tgtgtttttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000851             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:17019:12999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000851
VERSION     KCWK01000851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17019:12999"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..420
                     /note="immunoglobulin light chain variable region"
     V_region        90..420
     V_segment       90..382
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <345..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66589.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       384..420
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           90 a          153 c          111 g          104 t
ORIGIN      
        1 acatgggggc aggactcagg acaatctcca gcatggcctg gttccctctc gtcctcaccc
       61 tcctcactca ctgtgcaggg tcctgggccc agtctgtgct gactcagcct ccctcagcgt
      121 ctgaggccgc caggaagagt gtcaccatct cctgttctgg aagcacctcc aacatcggaa
      181 gcaataatgt atcctggtac cagcagctcc caggaacagc tcccaaactc ctcttttatt
      241 ataatgatca acgagcctca ggtgtctctg accgattctc ttgctccaag tctggcacgt
      301 cagcctccct ggccatcagt gggctccaga ccgaggatga ggctgattat tactgcgcag
      361 catgggatga taacctgagc ggctacatct tcggtgctgg gacccggctc accgtcctag
      421 gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01000852             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:19163:9778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000852
VERSION     KCWK01000852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:19163:9778"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66590.1"
                     /translation="DYYCSSYAGSNILFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          151 c          119 g          112 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag taatatttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000853             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:13425:16262
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000853
VERSION     KCWK01000853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:13425:16262"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66591.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       391..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           99 a          142 c          131 g           92 t
ORIGIN      
        1 acatgggggt ctgggtctca agaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gagctgactc
      121 aggcaccctc agtgtcagcg gcctcaggac agacggccag gatcacctgt ggcggagaca
      181 acattggaat taaaaatgtc cactggtacc agcagaagcc agcacaggcc cctgtggtag
      241 tcatctatgc tgataacaaa cggccctcag ggatccctga gcgactctct ggctccaact
      301 cagggaatat tgccaccctg accatcagca gggtcgaggc cggggatgag gcagactatt
      361 actgtcaggt gtgggacagt agtagtaaat gggtattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000854             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17147:18385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000854
VERSION     KCWK01000854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17147:18385"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66592.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          141 c          135 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccaaca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgcggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ctgatcatcc ggtgttgttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ttgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000855             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12774:18615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000855
VERSION     KCWK01000855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12774:18615"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66593.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       397..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           90 a          159 c          120 g          102 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca cttcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgtct ctgcctccct gggagcctcg gtcaaactca cctgtacttt gaacagtggg
      181 cacagcagct acaccatcgc atggcatcag cagcagcaag ggaaggcccc ccggtacttg
      241 atgtggctta aaagtgaagg cagccatagc aagggggacg ggatccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatact gacattgtgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000856             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:10042:18537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000856
VERSION     KCWK01000856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10042:18537"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66594.1"
                     /translation="DYYCAAWDNTLSGVFF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          151 c          126 g          114 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcttg ggcccagtct
      121 gtgttgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca gactcctcat ttattttaat gatcaacgta cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gataatacct tgagcggtgt gtttttcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01000857             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:12951:8875
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000857
VERSION     KCWK01000857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12951:8875"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..400
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66595.1"
                     /translation="DYYCSSCESSLNWVF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           85 a          152 c          129 g          111 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg ttaccatctc ctgcactggg
      181 agcagctcca acatcggggc gggtttttat gtgtcctggt accagcagtt ccctggaaca
      241 gcccccaaac tcctcatctt tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggttc ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgctc atcatgtgaa agcagcctga attgggtttt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000858             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:15363:19946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000858
VERSION     KCWK01000858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15363:19946"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66596.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          163 c          113 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaccaatg
      181 ttggtagtta caggattttc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacta ctcagactca actaagcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttgcatc ttcggtcctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000859             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:9139:14465
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000859
VERSION     KCWK01000859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9139:14465"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66597.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           98 a          141 c          131 g           90 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgagc tgactcaggc
      121 accctcagtg tcagcggcct caggacagac ggccaggatc acctgtggcg gagacaacat
      181 tggaattaaa aatgtccact ggtaccagca gaagccagca caggcccctg tggtagtcat
      241 ctatgctgat aacaaacggc cctcagggat ccctgagcga ctctctggct ccaactcagg
      301 gaatattgcc accctgacca tcagcagggt cgaggccggg gatgaggcag actattactg
      361 tcaggtgtgg gacagtagta gtaaatgggt attcggcgga gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000860             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:16859:20612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000860
VERSION     KCWK01000860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16859:20612"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..248
                     /note="immunoglobulin light chain variable region"
     V_region        4..248
     V_segment       4..213
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>220
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66598.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       218..248
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        249..>286
                     /gene="IGLC"
BASE COUNT           61 a           88 c           69 g           68 t
ORIGIN      
        1 acatgggtat tatcatgctg tgtcttggta ccaacatcat ccaggcaaag cccccaaact
       61 catgatttat gaggtcaata aacggcccgc aggggtctct gatcgcttct ctggctccaa
      121 gtctggcaac acggcctccc tgaccatctc tgggctccag actgaggatg aggctgatta
      181 ttactgcagc tcatatgcag gcagcaacac tttattcttc ggaggaggga cccggctgac
      241 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000861             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:22205:24194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000861
VERSION     KCWK01000861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22205:24194"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..434
                     /note="immunoglobulin light chain variable region"
     V_region        90..434
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66599.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>476
                     /gene="IGLC"
BASE COUNT           93 a          160 c          115 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 ctgcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatacaaatc agactcagat aaggaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ctcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ctactgtgcc attgggcaca gcagcggtga ttacatcttc gctgctggga
      421 cccgcctcac cgtcttaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000862             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:6826:5593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000862
VERSION     KCWK01000862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:6826:5593"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66600.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          161 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtcagtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatattgg caataaaaac atgtactggt accagcagaa gccagggagc gctcccaagt
      241 tattcctgta ctactactcc gactcagaca tgcagttggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000863             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:23693:8229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000863
VERSION     KCWK01000863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23693:8229"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..400
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66601.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          158 c          125 g          106 t
ORIGIN      
        1 acatggggct ggctgtggct caggaagcag agcctggagc atctccacca tggcctgggc
       61 tccactcctc ctcaccctcc tcgctcactg cacagggtct tgggctgagg ttgtgttcac
      121 tcagccccat tctgtgtcgg ggtctccggg gcagacggtc accatctcct gcacccgcag
      181 cagtggcagc attgacaacg gctttgtgta ctggtaccag cagcggccgg gcagcgctcc
      241 caccactgtg atttacaaag ataaccaaag accctctggg gtccctgatc ggttctctgg
      301 ctccatcgac agctcctcca actctgcctc cctcaccatc tctggactga aatctgagga
      361 cgaggctgac tattactgtc agtcttatga cagcagcagt gtattattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000864             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:13954:10055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000864
VERSION     KCWK01000864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13954:10055"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66602.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          163 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atttactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgcg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtgtgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000865             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:11623:7334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000865
VERSION     KCWK01000865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11623:7334"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66603.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           87 a          164 c          113 g          112 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc accaatgttg
      181 gtagttacag cattttctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaact aagcaccggg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc atttggcaca gcagcgcttc ttgcatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000866             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:10627:2917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000866
VERSION     KCWK01000866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:10627:2917"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66604.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          154 c          120 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tccagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaacagtgtc gccatctcct gttctggagg cagctccaac
      181 atcggcagtc atagtgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattatg atgatcaacg agcctcaggt gtctctggcc gattctctgg ctccaggtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagaggt tacatcttcg gtgatgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000867             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:21179:6228
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000867
VERSION     KCWK01000867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21179:6228"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66605.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       414..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           90 a          157 c          125 g          116 t
ORIGIN      
        1 atggggctct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcacttcac agttccaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag attattttgt gcagtggtac cagcaccttc
      241 caggaacggc ccccaaactc ctcatctatg aaaataataa gcggccctca gggatttctg
      301 atcgattctc tggctcccag tctggaacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagtttgatt gctgtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01000868             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:27333:7999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000868
VERSION     KCWK01000868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:27333:7999"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66606.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          159 c          127 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtctc catcccctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000869             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:20117:14887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000869
VERSION     KCWK01000869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:20117:14887"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66607.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          157 c          126 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 actcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattac tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000870             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:12328:13844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000870
VERSION     KCWK01000870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12328:13844"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66608.1"
                     /translation="DYYCCSYTTSSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          155 c          117 g          113 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctatgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 caccagtgac attggtggtt ataattatgt ctcctggtac cagcagcacc cagacaaagc
      241 ccccaaactc ataatttatg gtgtcagaaa tcggccctca ggggtctctt atcgcttctc
      301 tggctccaag tctggtaata cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgttgtt catatacaac cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000871             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:21663:12332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000871
VERSION     KCWK01000871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21663:12332"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..255
                     /note="immunoglobulin light chain variable region"
     V_region        8..255
     V_segment       8..218
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <183..>227
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66609.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       219..255
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        256..>293
                     /gene="IGLC"
BASE COUNT           61 a           84 c           82 g           66 t
ORIGIN      
        1 acatgggtgt attgccaaaa aaatatgctt attggttcca gcagaagcca ggccagtccc
       61 ctgtattggt catctctgag gacaccgaac ggccctctgg gatccctgag agattctctg
      121 gctccagctc agggacagtg gccaccttga ctatcagtgg ggcccaggtg gaggatgaag
      181 ctgactacta ctgttactca gcagacagta gtggtcatgg cttcttcgga ggagggaccc
      241 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000872             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:16291:16106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000872
VERSION     KCWK01000872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16291:16106"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..416
                     /note="immunoglobulin light chain variable region"
     V_region        100..416
     V_segment       100..386
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66610.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       387..416
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>456
                     /gene="IGLC"
BASE COUNT           89 a          141 c          127 g           99 t
ORIGIN      
        1 acatgggggg gctcagaagc agagctctgg ggtgtctcca ccatggcctg gactcctctc
       61 tggctcaccc tcctcagtct ttgcacaggt tctatggttt cttctgagct gactcaggac
      121 cctgcagtgt ctgtggcctt gggacagaca gtcaggatta cctgccaagg agacagcctc
      181 agaagctctt atgcaagctg gtaccaacag aggccaggcc aggcccctgt gctggtcgtc
      241 tatggtaaca actaccggcc ctcagggatc ccagagcgat tctctggctc ctactcacga
      301 aacacagctt ccttgaccat ctctggggct caggtggaag atgaggctga ctattactgt
      361 gactcctggg acagcagcgg aacccaattc ggaggaggga cccggctgac cgtcctgggt
      421 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000873             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:20543:8938
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000873
VERSION     KCWK01000873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20543:8938"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66611.1"
                     /translation="DYYCSSYGGRNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          154 c          121 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatggagg cagaaacact ttattcttcg caggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000874             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:21888:3443
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000874
VERSION     KCWK01000874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21888:3443"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66612.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           91 a          162 c          109 g          111 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggaacatca gccagactca gctgcacctt gagcagtggc aatgttggca
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggttc cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gatgatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt cctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000875             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:23115:12745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000875
VERSION     KCWK01000875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23115:12745"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..398
                     /note="immunoglobulin light chain variable region"
     V_region        102..398
     V_segment       102..359
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <326..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66613.1"
                     /translation="DYHCLAWDTSLNWIF"
     J_segment       368..398
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>436
                     /gene="IGLC"
BASE COUNT           86 a          141 c          108 g          101 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggcccccg gacagagggt
      121 caccatctcc tgcattagca gcagctccaa catcggggcg gcttattatg tatcctggta
      181 ccaacagttc ccaggaacag cccccaaact cctcatcttt gaaaataata agcgaccctc
      241 tggggtttct gaccgattct ctggctccaa gtctggtccc tcagcctccc tgaccatcac
      301 tggactccaa tctgaggatg aggctgatta tcactgttta gcatgggata ccagcctgaa
      361 ttggatcttc ggcggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      421 ggtcactctc ttcccg
//
LOCUS       KCWK01000876             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:22463:10734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000876
VERSION     KCWK01000876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:22463:10734"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..395
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66614.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       397..432
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           94 a          151 c          116 g          109 t
ORIGIN      
        1 acatggggct ggagccaggg atcccttcca atatcagcac catggcctgg actctgctcc
       61 tcctccagtt cctcctcact tgctgcccag ggtccaattc tcaggctgta gtgactcagg
      121 agccctcaat gactgtgtcc ccaggaggga cagtcactct cacctgtgct tccagcactg
      181 gagcagtcac cagtggtcac tctccacact ggttccagca gaaacctgga caagccccca
      241 agacactgat ttataataca aactacagac actcctggac tcctgcccgg ttctcaggct
      301 ccctccttgg gggtaaagct gccctgacac tgtcaggtgc gcagcctgag gatgaggctg
      361 agtattattg tttactgtac tatagtggtg ctcagctgtt attcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000877             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22511:12909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000877
VERSION     KCWK01000877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22511:12909"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66615.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          153 c          123 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtcgctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000878             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:12790:6305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000878
VERSION     KCWK01000878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12790:6305"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66616.1"
                     /translation="DYYCQVYDSSDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          162 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac ctgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgatgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000879             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12796:24836
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000879
VERSION     KCWK01000879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12796:24836"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..266
                     /note="immunoglobulin light chain variable region"
     V_region        3..266
     V_segment       3..229
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66617.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       230..266
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           61 a           95 c           73 g           75 t
ORIGIN      
        1 acatgggggt agttacagcg tattctggta ccagcagaag ccagggagtc ctccccggtt
       61 ccttctgtac tactactcag actcaagtaa acaccagggc tctggagtcc ccagccgctt
      121 ctctggatcc aaagatgctt cggccaatgc aggcctttta ctgatctcta ggctccagtc
      181 tgaagatgag gctgactatt actgtgccat atggcacagc agcgcttctt acttcttcgg
      241 tactgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      301 cccg
//
LOCUS       KCWK01000880             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:19688:18483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000880
VERSION     KCWK01000880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19688:18483"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..242
                     /note="immunoglobulin light chain variable region"
     V_region        10..242
     V_segment       10..203
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <167..>214
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66618.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       210..242
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        243..>280
                     /gene="IGLC"
BASE COUNT           50 a           88 c           85 g           57 t
ORIGIN      
        1 acatggggtt gtgaactggt accagcagaa gccagcgcag gcccctgtat tggtcatctt
       61 tgctgatacc gaacggcccg cagggatccc cgagcgattc tctggctcca aatcagggaa
      121 cacggccacc ctgaccatcc gcggggtcga ggccggggat gaggctgact tttactgtca
      181 ggtgtgggac attcgtagtg atcgtccgct attcggcgga gggacccggc tcaccgtcct
      241 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000881             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:12607:15444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000881
VERSION     KCWK01000881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12607:15444"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66619.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          153 c          116 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta ataatgtgtc ctggtaccag cacctcccag gaacagctcc caaactcctc
      241 atctattata atgatcaacg aggctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcgt gggatgatag cctgagcagt tacatcttcg ctgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000882             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20174:18315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000882
VERSION     KCWK01000882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20174:18315"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    56..386
                     /note="immunoglobulin light chain variable region"
     V_region        56..386
     V_segment       56..349
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <311..>358
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66620.1"
                     /translation="DYYCQSYDGSVSAVLF"
     J_segment       350..386
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        387..>424
                     /gene="IGLC"
BASE COUNT           75 a          138 c          109 g          102 t
ORIGIN      
        1 acatggggct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
       61 tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca ccctctcctg
      121 cactgggagc agctccaaca ttggagatta ttatgtgcag tggtaccagc agcttccagg
      181 aacggccccc aaactcctca tctatgaaaa taataagcga ccctcagggg tttctgctcg
      241 attctctggc tcccagtctg gttcctcagc ctccctgacc atcactggac tccagtctga
      301 cgatgaggct gattattact gtcagtccta tgatggcagt gtgagtgctg tgttattcgg
      361 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      421 cccg
//
LOCUS       KCWK01000883             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:2587:14205
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000883
VERSION     KCWK01000883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:2587:14205"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66621.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           98 a          140 c          131 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga gctgactcag
      121 gcactttcag tgtcagcggc ctcaggacag acggccagga tcacctgtgg cggagacaac
      181 attggaatta aaaatgtaca ctggtaccag cagaagccac cacaggcccc tgtggtggtc
      241 atctatgctg ataacaaacg gccctcaggg atccctgagc gactctctgg ctccaactca
      301 gggaatattg ccaccctgac catcagcagg gtcgaggccg gggatgaggc agactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg gtattcggcg gagggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000884             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:7412:15127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000884
VERSION     KCWK01000884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7412:15127"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66622.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       415..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          156 c          126 g          108 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg gttcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agcgtctggg gcccccggac agagggtcac catctcctgc
      181 atgagcagca gctccaacat cggggcggca tattatgtat cctggtacca acagttccca
      241 ggaacagccc ccaaagtcct catctttgaa aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggtccctca gcctccctga ccatcactgg actccaatct
      361 gaggatgagg ctgattatta ctgtttagca tgggatacca gcctgaattg gatcttcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01000885             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18667:16043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000885
VERSION     KCWK01000885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18667:16043"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66623.1"
                     /translation="VYYCAIGHSSGLYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           87 a          157 c          120 g          112 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgtctacca cgtacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggggt ccccagccgc ttctctggat
      301 ccagtaatgc ttcagcgaac acagggattt tacgcatttc tgggctccag tctgaggatg
      361 aggctgtcta ttactgtgcc attgggcaca gcagcggtct ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000886             498 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:22654:13477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000886
VERSION     KCWK01000886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 498)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22654:13477"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..460
                     /note="immunoglobulin light chain variable region"
     V_region        112..460
     V_segment       112..396
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>432
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66624.1"
                     /translation="DYYCQSYDSQSYDTSLSVRVF"
     J_segment       425..460
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        461..>498
                     /gene="IGLC"
BASE COUNT           87 a          163 c          134 g          114 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacatcgg ggcgggttat tatgtgcggt ggtaccagca gcttccagga
      241 acggcccccc aactcctcat ctatgatact tataagcgac cctcaggggt ttctgatcga
      301 atctctggct ccaagtctgg tacctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagccagt cctatgacac cagtttgagt
      421 gttcgggttt tcggcggtgg gacccggcta accgtcctag gtcagcccaa ggctgccccc
      481 tcggtcactc tcttcccg
//
LOCUS       KCWK01000887             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:24654:5655
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000887
VERSION     KCWK01000887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24654:5655"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..439
                     /note="immunoglobulin light chain variable region"
     V_region        93..439
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66625.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>479
                     /gene="IGLC"
BASE COUNT           92 a          162 c          111 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtagtg
      421 ggacccggct caccgtcctg ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000888             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:25000:7149
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000888
VERSION     KCWK01000888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:25000:7149"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    33..378
                     /note="immunoglobulin light chain variable region"
     V_region        33..378
     V_segment       33..341
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <309..>353
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66626.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       344..378
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        379..>419
                     /gene="IGLC"
BASE COUNT           86 a          137 c          101 g           95 t
ORIGIN      
        1 acatgggctc tcactgcaca ggttccctct ccaaaccttt gctgactcag ccggcctccc
       61 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      121 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cagtttcttc
      181 tgagatacaa atcagactca gatcagggcc agggctctgg agtccccagc cgcttctctg
      241 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      301 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacata ttcggtgctg
      361 ggacccggct caccgtccca ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000889             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:25291:6901
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000889
VERSION     KCWK01000889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:25291:6901"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..441
                     /note="immunoglobulin light chain variable region"
     V_region        96..441
     V_segment       96..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66627.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          163 c          112 g          111 t
ORIGIN      
        1 acatggggcc cactgcaggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcccagcc tgtgctgacc cagccaacct
      121 ccctctcagc atctccggga gcatcagcca gactcagctg caccttgagc agtggcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tttactacta ctcagactca agtaaccacc aggactctgg agtccccagc cgcttctctg
      301 gatcgaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccacatggc acagcagcgc ttcttacatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000890             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:16403:6219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000890
VERSION     KCWK01000890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16403:6219"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66628.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           92 a          145 c          133 g           92 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg acagtaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000891             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:22555:9314
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000891
VERSION     KCWK01000891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22555:9314"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..287
                     /note="immunoglobulin light chain variable region"
     V_region        5..287
     V_segment       5..244
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <212..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66629.1"
                     /translation="AYYCQVWDGDSDHYIF"
     J_segment       250..287
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>325
                     /gene="IGLC"
BASE COUNT           71 a           96 c           93 g           65 t
ORIGIN      
        1 acatgggcag acggccagga tcacctgtgg gggagacaac attggaacta attttgtgca
       61 ctggtaccag cagaagccag cgcaggcccc tatgcaggtc atctatgctg ataacaaacg
      121 gccctcaggg atccctgaga gattctctgg ctccaactca gggaacaccg ccaccctgac
      181 catcagcgga gtcgaggccg gggatgaggc tgcctattac tgtcaggtgt gggacggtga
      241 tagtgatcat tacatcttcg gtgctgggac ccggctcacc gtcctaggtc agcccaaggc
      301 ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000892             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:17640:8496
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000892
VERSION     KCWK01000892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17640:8496"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66630.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          140 c          135 g          100 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccagcctcgg tgtcagtgtc cccgggacag acggccagga tcacctgtgg gggagacaat
      181 attggaagta aaaatgtgca ctggtaccag caggagccac cgcaggcccc tgtgttggtc
      241 atcttttatg ataacaaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacatcg ccaccctgac catcagcgag gccgaggccg gggatgaggc tgactattac
      361 tgtcagctgt gggacagtag tgttgatcat ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000893             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:26042:14854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000893
VERSION     KCWK01000893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:26042:14854"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66631.1"
                     /translation="DYYCAAWDDNLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           97 a          158 c          119 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcagcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000894             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:16837:21104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000894
VERSION     KCWK01000894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16837:21104"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..269
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <237..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66632.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       272..306
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           63 a          111 c           93 g           77 t
ORIGIN      
        1 acatgggggg gtctccgggg cagacggtca ccatctcctg cacccgcagc agtggcagca
       61 ttggcaacag ctatgtgtac tggttccagc agcggccggg cagcgtcccc actattgtga
      121 tttacaaaga tgaccaaaga ccctctgggg tccctgatcg gttctctggc tccatcgaca
      181 gctcctccaa ctctgcctcc ctcaccatct ctggactgaa gtctggggac gaggctgact
      241 attactgtca gtcttttgac agcagcagtg tcttattcgg aggagggacc cggctgaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000895             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:5336:16730
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000895
VERSION     KCWK01000895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:5336:16730"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    77..401
                     /note="immunoglobulin light chain variable region"
     V_region        77..401
     V_segment       77..363
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <326..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66633.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       365..401
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>439
                     /gene="IGLC"
BASE COUNT           86 a          141 c          119 g           93 t
ORIGIN      
        1 acatgggggt gcctcagcca tggcctggac ttttctcctc ctcggcctcc ttgcttactg
       61 cacaggctct gcggcctcct atgatctgac tcagccaccc tcggtgtcag tgtccccagg
      121 acagacggcc aggatcacct gtgggggaga caacattgga agtcaaagtg tgcactggta
      181 ccagcacaag ccaccgcagg cccctgtact ggtcatcttt tattataccg aacggccctc
      241 aggaatccct gagcgattct ctggctccaa atcagggaac accgccaccc tgaccatcag
      301 cggggtcgag gccggggatg aggctgacta ttactgtcag gtgtgggaca caactattga
      361 tcacggctta ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc
      421 ctcggtcact ctcttcccg
//
LOCUS       KCWK01000896             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:22655:14806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000896
VERSION     KCWK01000896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22655:14806"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66634.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          162 c          110 g          110 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagg ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000897             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:16744:9938
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000897
VERSION     KCWK01000897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16744:9938"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66635.1"
                     /translation="DYYCQVYDSSAHVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          164 c          124 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtggtg actcagccac
      121 cctccctgtc tgcatccccg ggagcgtcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tatccctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggcctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctcat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000898             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:20900:6759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000898
VERSION     KCWK01000898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20900:6759"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66636.1"
                     /translation="DYYCCSYRSGPTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          157 c          127 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccaa
      181 cagtgacatt ggaggttata gtggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 caaactcctg atttatgatg tgaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctgctcat ataggagtgg acccacttgg gttttcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000899             496 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:14772:15517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000899
VERSION     KCWK01000899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 496)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14772:15517"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..458
                     /note="immunoglobulin light chain variable region"
     V_region        110..458
     V_segment       110..421
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>430
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66637.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       422..458
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        459..>496
                     /gene="IGLC"
BASE COUNT           92 a          169 c          123 g          112 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      181 gagtagtgac ctcagtgttg gtagtaaaaa catctactgg taccagctga agccagggag
      241 cgctcccagg tcattcctgt actactactc cgactcagac aagcagctgg gacctggggt
      301 ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc
      361 tgggctccag cctgaggacg aggccgatta ttactgtcag gtctatgaca gtagtgctaa
      421 tgtgttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      481 ggtcactctc ttcccg
//
LOCUS       KCWK01000900             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:18000:7619
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000900
VERSION     KCWK01000900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18000:7619"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66638.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       404..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          155 c          118 g          112 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgcgcagt ggcatcagtg
      181 tcggtagtta caggatcttc tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gagaaacacc agggatctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcgt ctctggcctc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttatgtgtta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000901             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:27992:6606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000901
VERSION     KCWK01000901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:27992:6606"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..400
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66639.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           87 a          152 c          128 g          110 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg tcaccatccc ctgctctggg
      181 agcagctcca acatcggggc gggtttttat gtttcctggt accagcagtt cccaggaaca
      241 gcccccaaac tcctcatctt tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggttc ctcagcctcc ctgaccatca ctggactcca atctgaggat
      361 gaggctgatt attattgttc atcatgggaa agcagcctga attgggtatt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000902             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:22028:9887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000902
VERSION     KCWK01000902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22028:9887"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66640.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          148 c          130 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccgatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta agagtgtgca ctggtaccaa cacaagccac cgcaggcccc tatcctggtc
      241 atctattatt ataccgaacg gccctcggcg atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacactac tattgatcat ggctttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000903             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:5471:10127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000903
VERSION     KCWK01000903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5471:10127"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66641.1"
                     /translation="DYSCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           97 a          161 c          111 g          107 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcaactcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgactacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 gttacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaaaatac ttcaacgaac acaggcattt tacacatctc tgggctccag tctgaggatg
      361 aggctgacta ttcctgtgcc attggacaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000904             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:10559:20487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000904
VERSION     KCWK01000904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10559:20487"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..331
                     /note="immunoglobulin light chain variable region"
     V_region        114..331
     V_segment       114..294
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <259..>303
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66642.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       297..331
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        332..>369
                     /gene="IGLC"
BASE COUNT           66 a          130 c           91 g           82 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcacca gtcagactca aggaaacacc agggctctgg agtccccagc
      181 cgcttctctg gatccaaaga tgcttcagcc aatgcagggc tgttactgat ctctgggctc
      241 cagtctgaag atgaggctga ctattactgt gccctatggc acagcagcgc ttcttgcatc
      301 ttcggtggtg ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact
      361 ctgttcccg
//
LOCUS       KCWK01000905             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:22604:4319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000905
VERSION     KCWK01000905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22604:4319"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    69..390
                     /note="immunoglobulin light chain variable region"
     V_region        69..390
     V_segment       69..354
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <318..>362
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66643.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       358..390
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        391..>428
                     /gene="IGLC"
BASE COUNT           88 a          133 c          119 g           88 t
ORIGIN      
        1 acatgggagc catggcctgg acccttctcc tcctcggcct cctcgcttac tgcacaggct
       61 ctgcgacctc ctatgaattg actcagtcac cctcagtgtc agcggcctca ggacagccgg
      121 ccaggatcac ctgtggggga gacaacattg gaactaaaac tgtgcactgg taccaacaga
      181 agccaccgca gggccctgta ttggtcatct ttgctgatag tagacggccc tcagggatcc
      241 ctgagcgatt ctctggctcc aattcaggga acaccgccac cctgaccatc agcagggtcg
      301 aggccgggga tgaggctgac tattactgtc aggtgtggga cagtagtagt aaatggatat
      361 tcggcggggg gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      421 tcttcccg
//
LOCUS       KCWK01000906             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:22504:19083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000906
VERSION     KCWK01000906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:22504:19083"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..389
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66644.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          154 c          113 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cacctccaac
      181 atcggaagca ataatgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 ttttattata atgatcaacg agcctcaggt gtctctgacc gattctcttg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgataa cctgagcggc tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000907             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16078:22593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000907
VERSION     KCWK01000907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16078:22593"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66645.1"
                     /translation="DYYCQVWDISTDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          144 c          134 g          100 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag cctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccagggt cacctgtgga ggagacaacc
      181 ttggatatga agttgtcaac tggtaccagc agaagccacc gcaggcccct gtggtggtca
      241 tctatgctga ttatgaacgg ccctcaggga tccctaaccg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcggag tcgaggccgg ggatgaggct gactattatt
      361 gtcaggtgtg ggacattagt actgaccatc cggtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000908             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:9805:6249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000908
VERSION     KCWK01000908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:9805:6249"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..420
                     /note="immunoglobulin light chain variable region"
     V_region        90..420
     V_segment       90..385
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66646.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       387..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           82 a          152 c          114 g          110 t
ORIGIN      
        1 acatggggca gcgctctcag gacttctcca ccatggtctg ggctctgctc ctcctcaccc
       61 tcctcactca gggcacagga tcctgggttc aggctgcccc gactcagcct ccctctgtgt
      121 ccgggtctcc tggacagtcg gtcaccatct cctgcactgg aacgagcagt gatattggct
      181 attataacgc tgtgtcttgg taccaacagc atccaggcaa agcccccaaa ctcatcattt
      241 ttgacgtcat taagcggccc tcaggggtct ctgatcgctt cgctgcctcc aagtctggcg
      301 acacggcctc cctgaccatc tctgggctcc gggctgagga tgaggctgat tattactgca
      361 gctcatatgc cggcagaaat aattttttat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000909             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:12879:12593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000909
VERSION     KCWK01000909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12879:12593"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66647.1"
                     /translation="DYHCQVWDINSHHLLF"
     J_segment       391..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          143 c          134 g           99 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag tctctgcggc ctcctatgat ctgactcagc
      121 caccctcgat ttcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtgaac tggtaccaac agaagccacc gctggcccct gtgttggtca
      241 tctatgctga tagcgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaccacggc caccctgagc atcagcgggg tcgaggccgg ggatgaggct gactatcact
      361 gtcaggtgtg ggacattaat agccatcatc tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000910             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:28782:9410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000910
VERSION     KCWK01000910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:28782:9410"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66648.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           84 a          148 c          137 g           94 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcccatgatc tgactcagcc
      121 accctcggtg accgtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tcgaagtgaa gttgtgaact ggtaccagca gaagccagcg caggcccctg tattggtcat
      241 ctttgctgat accgaatggc ccgcagggat ccccgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tccgcggggt cgaggccggg gatgaggctg acttttactg
      361 tcaggtgtgg gacattcgta gtgatcgtcc gctattcggc ggagggaccc ggctcaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000911             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:14304:3946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000911
VERSION     KCWK01000911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14304:3946"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66649.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          162 c          111 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcaactcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ttgcctacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 gttacaaatc agactcagat aagggccagg gctccggagt ccccagccgc ttctctggat
      301 ccaaaaatgc ttccacaaac acaggcattt tacacatctc tgggctccag tctgaggatg
      361 aggctgacta tttctgtgcc attggacaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000912             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:13135:7128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000912
VERSION     KCWK01000912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13135:7128"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66650.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          152 c          120 g          111 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggt gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000913             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:22770:10822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000913
VERSION     KCWK01000913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22770:10822"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..443
                     /note="immunoglobulin light chain variable region"
     V_region        95..443
     V_segment       95..406
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66651.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           94 a          164 c          113 g          110 t
ORIGIN      
        1 acatggggcc actgtgggga aagaggctgt gtccaccatg gcctggactc ctctcctcct
       61 cctgctcctc tctcactgca caggttccct ctccaagcct atgctgactc agccggcctc
      121 cctctcagca actcctggag catcagccag tctcacatgc accttcagcg gtggcatcaa
      181 tgttgctgcc taccacatac actggtacca gcagaagcca gggagtcccc cccggtatct
      241 tctgagttac aaatcagact cagataaggg ccagggctct ggagtcccca gccgcttctc
      301 tggatccaaa aatgcttcaa cgaacgcagg catttttcac atctctgggc tccagtctga
      361 ggatgaggct gactatttct gtgccattgg acacagcagc ggtccttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01000914             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:7125:12695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000914
VERSION     KCWK01000914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7125:12695"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66652.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           87 a          158 c          125 g          111 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggcac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcttggga tgatagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcgccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01000915             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:19487:9943
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000915
VERSION     KCWK01000915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19487:9943"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66653.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          158 c          124 g          106 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaagtc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catatacagg catcaacagt tacatcttcg gtggtgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000916             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:15151:7424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000916
VERSION     KCWK01000916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:15151:7424"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..388
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66654.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       389..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           90 a          142 c          127 g           99 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagagctct ggggtgtctc caccatggcc tggactcctc
       61 tctggctcac cctcctcagt ctttgcacag gttctatggt ttcttctgag ctgactcagg
      121 accctgcagt gtctgtggcc ttggggcaga cagtcaggat tacctgccaa ggagacagcc
      181 tcagaagctc ttatgcaaac tggtaccaac agaggccagg ccaggcccct gtgctggtcg
      241 tctatggtaa caactaccgg ccctcaggga tcccagagcg attctctggc tcctactccc
      301 gaaacacagc ttccttgacc atcactgggg ctcaggtgga agatgaggct gactattact
      361 gtgactcctg ggacagcagc ggaacccaat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000917             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:12648:8340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000917
VERSION     KCWK01000917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12648:8340"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66655.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       394..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          148 c          121 g          105 t
ORIGIN      
        1 acatggggag ctgtgggctc agaagcagaa ctctgggtcc tctccaccat ggcctggacc
       61 cctcccctgc tcatcctcct cactctctgc acaggttccg tggtttcctc tgagctgact
      121 caggagcctg cattgtctgt ggccttggga caaacagtca ggatgacctg ccaaggagac
      181 agcctcaaaa cctattatgc aagctggtac cagcagaagc caggccaggt ccctgtgctg
      241 gtcatctatg gtaacaacta ccggccctca gggatcccag gccgattctc tgtctcctgg
      301 tcaggaaaca caggttcctt gaccatcact gcggctcagg tggaagatga ggctgactat
      361 tactgtaagt cctgggacag cagtggtacc cattacatct tcggtgctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01000918             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10951:7605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000918
VERSION     KCWK01000918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10951:7605"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66656.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       407..440
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           86 a          158 c          125 g          109 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggcggtt ataactatgt ctcctggtac caacaacatc cagacacagc
      241 ccccaaactc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctcctgg ctgaggacga
      361 ggctgattat tactgctgct cacatgcagg cagtgatatt ttcgtattat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000919             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:14956:19911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000919
VERSION     KCWK01000919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14956:19911"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..440
                     /note="immunoglobulin light chain variable region"
     V_region        92..440
     V_segment       92..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66657.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       406..440
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           92 a          160 c          112 g          114 t
ORIGIN      
        1 acatgggact gcagggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc ccagcctgtg ctgacccagc caacctccct
      121 ctcagcatct ccgggagcat cagtcagact cagctgcacc ttgagcagtg gcatcaatgt
      181 tggttcttac accatattct ggtaccagca gaagccaggg agtcctcccc ggttccttct
      241 gtactactac tcagactcaa ataatcacca gggctctgga gtccccagcc gcttctctgg
      301 atccaaagat gcttcagcca atgcagggct tttactgatc tctgggctcc agtctgaaga
      361 tgaggctgac tattactgtg ccatgtggca cagcagcgct tatgccttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000920             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:5021:8291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000920
VERSION     KCWK01000920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5021:8291"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66658.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          163 c          120 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgccc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000921             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:14873:18113
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000921
VERSION     KCWK01000921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14873:18113"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66659.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          164 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatattgg caataaaaac atgtactggt accagcagaa gccagggagc gctcccaagt
      241 tcttcctgta ctactactcc gactcagaca tgcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagccc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000922             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:22122:12378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000922
VERSION     KCWK01000922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22122:12378"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66660.1"
                     /translation="DYYCQVWDTTLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          148 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaactc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000923             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:11287:3455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000923
VERSION     KCWK01000923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11287:3455"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66661.1"
                     /translation="DYYCQVWDSSSEWVF"
     J_segment       388..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           89 a          147 c          135 g           91 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcag tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaaggcag cgcaggcccc tgtgctggtc
      241 atctttgctg ataccaaacg gccctcaggg atccctgacc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtgagtgg gttttcggcg gagggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000924             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:21954:14242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000924
VERSION     KCWK01000924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21954:14242"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66662.1"
                     /translation="DYYCQSTDTSGNYIF"
     J_segment       389..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          106 a          133 c          121 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagcaat
      181 actggcaaaa aaatatgctc agtggttgca gcagaagcca ggccaggccc ctgtgttgat
      241 aatatataaa gatagtgaga ggccctcagg gatccctgag cgattctcta gttccagttc
      301 agggacaaca gttgccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca acagacacca gtggtaatta catcttcggt gctgggaccc ggctcaacgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01000925             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:13324:19281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000925
VERSION     KCWK01000925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13324:19281"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66663.1"
                     /translation="DINCHSADSSGNHWVF"
     J_segment       389..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          102 a          132 c          127 g          102 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgttctg gagaaatact
      181 ggcaaaaaaa tatggtcagt ggttccagca gaagccaggc caggcccctg ttgtggtgat
      241 atataaggac agtgagaggc cctcagggat ccctgagcga ttctctaggt ccatttcagg
      301 gacaacaatt accttgacca tctgtggggc cccggcagaa gatgaggctg acattaactg
      361 tcattcagca gacagcagtg gtaatcattg ggtcttcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000926             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:12409:13064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000926
VERSION     KCWK01000926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12409:13064"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..392
                     /note="immunoglobulin light chain variable region"
     V_region        76..392
     V_segment       76..362
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66664.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       363..392
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>432
                     /gene="IGLC"
BASE COUNT           84 a          136 c          116 g           96 t
ORIGIN      
        1 acatggggtg tctccaccat ggcctggact cctctctggc tcaccctcct cagtctttgc
       61 acaggttcta tggtttcttc tgagctgact caggaccctg cagtgtctgt ggccttggga
      121 cagacagtca ggattacctg ccaaggagac agcctcagaa gctcttatgc aagctggtac
      181 caacagaggc caggccaggc ccctgtgctg gtcgtctatg gtaacaacta ccggccctca
      241 gggatcccag agcgattctc tggctcctac tcacgaaaca cagcttcctt gaccatctct
      301 ggggctcagg tggaagatga ggctgactat tactgtgact cctgggacag cagcggaacc
      361 caattcggag gagggacccg gctgaccgtc ctgggtcagc ccaaggctgc cccctcggtc
      421 actctcttcc cg
//
LOCUS       KCWK01000927             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:9800:7651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000927
VERSION     KCWK01000927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9800:7651"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66665.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          156 c          128 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtc cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaggca gctccaacat cggaagtcat agtgtatcct ggtaccagca ggtcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctggccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000928             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:19268:14830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000928
VERSION     KCWK01000928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19268:14830"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66666.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       407..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           80 a          160 c          128 g          107 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcagcact cagggacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tactgttgct catataggag tggcaacact tggctcttcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000929             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:9367:8679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000929
VERSION     KCWK01000929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:9367:8679"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66667.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       391..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           90 a          143 c          135 g           95 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccagca gaaggcaccg caggcccctg tcctggtcat
      241 ctatgctaat aacgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg ggcgttacta gtgatcatcc cttattcgga ggagggaccc ggctgaccgt
      421 ccaaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000930             345 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:26240:7800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000930
VERSION     KCWK01000930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 345)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:26240:7800"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..307
                     /note="immunoglobulin light chain variable region"
     V_region        8..307
     V_segment       8..267
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <235..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66668.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       270..307
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>345
                     /gene="IGLC"
BASE COUNT           70 a          105 c           92 g           78 t
ORIGIN      
        1 acatgggcag ccagtctcac atgcaccttc agcggtggca tcaatgttgc tggctaccac
       61 atacactggt accagcagaa gtctgggagt cctccccggt atcttctaag atacaaatca
      121 gactcggatc agggccaggg ctctggggtc cccagccgct tctctggatc caaagatgct
      181 tcagcgaaca cggggatttt acacgtctct gggctccagt ctgaggatga ggctgactat
      241 tactgtgcca ttgggcacag cagcggtgat tacatcttcg gtgctgggac ccggctcacc
      301 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000931             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:18348:19761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000931
VERSION     KCWK01000931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18348:19761"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66669.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          162 c          122 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccctg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000932             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:19137:19779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000932
VERSION     KCWK01000932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19137:19779"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66670.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          147 c          131 g           97 t
ORIGIN      
        1 acatgggggg gcctcgggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccaaca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000933             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:14061:13173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000933
VERSION     KCWK01000933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14061:13173"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66671.1"
                     /translation="AYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          157 c          117 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catacactgg taccagcaga agccagggag tcctccccga tatcttctga
      241 gattcaaatc ggactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgccta ttactgtgcc attggacaca gcagcggtga ttacatcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000934             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:18507:4238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000934
VERSION     KCWK01000934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18507:4238"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66672.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       390..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           87 a          139 c          135 g          101 t
ORIGIN      
        1 acatggggga ctttgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctttacaggc tctgtgacct cctatgagtt gcctcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtaata gtgtgcattg gtaccagcag aagccaccgc gggcccctgt attggtcatc
      241 tctgttgata gcgaacggcc ctcagggatc cctgagcgat tctctggttc cagatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg ataatattta taaatacgcg gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000935             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:23799:12278
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000935
VERSION     KCWK01000935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:23799:12278"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..391
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66673.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       392..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          152 c          120 g          103 t
ORIGIN      
        1 acatggggga cagaaggcag gactcaggac aatctccagc atggcctggt tccctctcgt
       61 cctcaccctc ctcactcact gtgcagggtc ctgggcccag tctgtgctga ctcagcctcc
      121 ctcagcgtct gaggccgcca ggaacagtgt cgccatctcc tgttctggaa gcagctccaa
      181 catcggaagt catagtgtat cctggtacca gcagctccca ggaacagctc ccaaactcct
      241 catctattat gatgatcaac gagcctcagg tgtctctgac cgattctctg gctccaggtc
      301 tggcacgtca gcctccctgg ccatcagtgg gctccagacc gaggatgagg ctgattatta
      361 ctgcgcagca tgggatgata gcctgagagg ttacatcttc ggtgatggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000936             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:7794:20923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000936
VERSION     KCWK01000936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7794:20923"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66674.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           94 a          155 c          126 g          106 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagag ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag actccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagaaatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agcgggctcc aggccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01000937             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:22170:12277
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000937
VERSION     KCWK01000937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22170:12277"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66675.1"
                     /translation="HYYCQVWDISSEHVLF"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          143 c          135 g           99 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gcctctgcgg cctcctatga actgactcag
      121 ccaccctcgg tgtcagtgtc ccccggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg atgttgtgaa ttggtaccac cagaagccac cgcaggcccc tgtactggtc
      241 atctatgctg atagcgatcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tcactattac
      361 tgtcaggtgt gggacattag tagtgagcat gtattattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000938             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:14929:19116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000938
VERSION     KCWK01000938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14929:19116"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66676.1"
                     /translation="DYFCAAWDDSLTGYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           94 a          158 c          122 g          110 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcctcc tcaccctcct cactcactgt gcagggtcca gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aagagtgtca ccatctcctg
      181 ttctggaacc agctccaaca tcggaagtaa tagtgtatcc tggtaccagc agctcccaga
      241 aacgtctccc aaactcctca tctattataa tgatcggcga gcctcaggtg tctctgaccg
      301 attctctggc tccaagtctg gcacgtcagc ctccctggcc atcagtgggc tccagaccga
      361 ggatgaggct gattatttct gcgcagcatg ggatgatagc ctgaccggtt acattttcgg
      421 tactgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01000939             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:16292:8226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000939
VERSION     KCWK01000939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16292:8226"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..430
                     /note="immunoglobulin light chain variable region"
     V_region        93..430
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66677.1"
                     /translation="VYYCAIGHSSGLYIF"
     J_segment       404..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>454
                     /gene="IGLC"
BASE COUNT           83 a          148 c          114 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacgtacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg ggtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgaggctgt ctattactgt gccattgggc acagcagcgg tctttacatc ttcggtgctg
      421 ggacccggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000940             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:27179:6663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000940
VERSION     KCWK01000940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:27179:6663"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66678.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          163 c          108 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt tagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctc ttcccg
//
LOCUS       KCWK01000941             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:18678:8748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000941
VERSION     KCWK01000941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18678:8748"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66679.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           91 a          141 c          134 g          102 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gactctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaggccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcaacgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000942             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:20720:14643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000942
VERSION     KCWK01000942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20720:14643"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..277
                     /note="immunoglobulin light chain variable region"
     V_region        10..277
     V_segment       10..240
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <202..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66680.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       241..277
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>315
                     /gene="IGLC"
BASE COUNT           65 a           95 c           91 g           64 t
ORIGIN      
        1 acatggggga tcacctgtgg gggagacaac attggaagta agagtgtgca ctggtaccag
       61 cacaagccac cgcaggcccc tgtgctggtc atctattatt ataccgaacg gccctcggcg
      121 atccctgagc gattctctgg ctccaaatca gggaacaccg ccaccctgac catcaccggg
      181 gtcgaggccg gggatgaggc tgactattac tgtcaggtgt gggacactac tattgatcat
      241 ggcttcttcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      301 gtcactctct tcccg
//
LOCUS       KCWK01000943             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14973:18896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000943
VERSION     KCWK01000943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14973:18896"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..436
                     /note="immunoglobulin light chain variable region"
     V_region        90..436
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66681.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       404..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           88 a          162 c          113 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcatctt gagcagtggc accaatgttg
      181 gtagttacag cattttctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaact aagcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatga ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc atttggcaca gcagcgcttc ttgcatcttc ggtcctggga
      421 cccggctcac cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000944             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:16197:20728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000944
VERSION     KCWK01000944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16197:20728"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66682.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          150 c          121 g          114 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gttcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattata acgctgtgtc ttggtatcaa cagcatccag gcaaagcccc
      241 caaactcata atttttgacg tcattaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcgacacgg cctccctgac catctctggg ctccgggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag aaataatttt ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000945             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:5667:6681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000945
VERSION     KCWK01000945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:5667:6681"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..446
                     /note="immunoglobulin light chain variable region"
     V_region        98..446
     V_segment       98..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66683.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          163 c          122 g          110 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt ggtaaaaaca tgtactggta ccagcagaag ccagggcgcg ctcccaggtt
      241 tttcctgtac tacaactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg gtcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcacgt atatgacagc agtactaatg tgttgttcgg
      421 aggagggacc cgtctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01000946             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:7520:6183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000946
VERSION     KCWK01000946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:7520:6183"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66684.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          160 c          114 g          109 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aatcaccagg actctggagt ccccagccgc ttctccggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggggggggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000947             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:11398:9997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000947
VERSION     KCWK01000947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11398:9997"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66685.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       410..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          157 c          128 g          107 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcctcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata gtgtttcctg gtaccagcag ctcccagaaa
      241 cggctcccaa actcctcatc ttttataatg atcggcgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagcggtccg gtattcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000948             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:8385:13909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000948
VERSION     KCWK01000948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:8385:13909"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66686.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          159 c          120 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacggg cctcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcatcatgg gatgataccc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000949             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:19222:7370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000949
VERSION     KCWK01000949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19222:7370"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66687.1"
                     /translation="DYYCCSYRSENTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          156 c          124 g          110 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gtattggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcaacact cagagacagc
      241 ccccacactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tactgttgtt catataggag tgaaaacact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000950             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:7541:13208
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000950
VERSION     KCWK01000950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7541:13208"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66688.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          158 c          116 g          112 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgccc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaagctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccaa
      181 cagtgatatt gggtcttata atgctgtgtc ttggtaccaa cagcgtccag gcaaagcccc
      241 ccaactcata gtttttgagg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaactct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgctgctcat atgtaggcag caacacttac atcttcgatg ttgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01000951             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:17646:12991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000951
VERSION     KCWK01000951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17646:12991"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66689.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           82 a          146 c          139 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtccgtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttcgaagtga agttgtgaac tggtaccagc agaagccagc gcaggcccct gtgttggtca
      241 tctttgctga taccgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atccgcgggg tcgaggccgg ggatgaggct gacttttact
      361 gtcaggtgtg ggacattcgt agtgatcgtc cgctattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000952             328 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:2756:10643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000952
VERSION     KCWK01000952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 328)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:2756:10643"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..290
                     /note="immunoglobulin light chain variable region"
     V_region        8..290
     V_segment       8..253
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>262
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66690.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       255..290
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        291..>328
                     /gene="IGLC"
BASE COUNT           70 a           90 c          104 g           64 t
ORIGIN      
        1 acatggggga cagacggcca ggatcacctg tgggggagac aacattggaa gtgaagttgt
       61 gaactggtac cagcagaagc caccgcaggc ccctgtgttg gtcatgtatg ctgatagcga
      121 gcggccctca gggatccctg agcgattctc tggctccaaa tcagggaaca cggccaccct
      181 gaccatcagc ggggtcgagg ccggggatga ggctgactat tactgtcagg tgtgggacat
      241 gaatagtcat catctgttat tcggaggagg gacccggctg accgtcctag gtcagcccaa
      301 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01000953             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:18432:13335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000953
VERSION     KCWK01000953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18432:13335"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66691.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          139 c          135 g          101 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccagtctcgg tgtcagtgtc cccgggacag acggccagga tcacctgtgg gggagacaat
      181 attggaagta aaaatgtgca ctggtaccag caggagccac cgcaggcccc tgtgttggtc
      241 atcttttatg ataacaaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacatcg ccaccctgac catcagcgag gccgaggccg gggatgaggc tgactattac
      361 tgtcagctgt gggacagtag tgttgatcat ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000954             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:9781:17773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000954
VERSION     KCWK01000954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9781:17773"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66692.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          162 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc actcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01000955             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:21019:6517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000955
VERSION     KCWK01000955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21019:6517"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..400
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66693.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           92 a          153 c          122 g          108 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctcctct
       61 cctcctcacc cttctcattc actgcacagt tccagggtcc tgggcccagt ctgtgctgac
      121 gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag
      181 cagctccaac attggagatt attatgtgca gtggtaccag caccttccag gaacggcccc
      241 caaactcctc atctatgaaa ataataagcg accctcaggg atttctgatc gattctctgg
      301 ctcccagtct ggaacctcag cctccctgac catcactgga ctccagtctg aggatgaggc
      361 tgattattac tgccagtcct atgacagcag tttgattgct gtgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000956             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:4406:7846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000956
VERSION     KCWK01000956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4406:7846"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..402
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66694.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           82 a          157 c          129 g          108 t
ORIGIN      
        1 acatgggggg ctggggtctc aggaggcagc gctctcggga cgtctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag tctgccctga
      121 ctcagcctcc ctcagtgtcc aagtctcttg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga cattggtggt tatgatggcg tctcctggta ccagcagcac tcagggacag
      241 cccccagact cctgatttat gatgtcacta agcggccctc aggggtctcg gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tcaccatctc tgggctccag actgaggacg
      361 aggctgatta ttattgttgc tcatatagga gtggaaacac ttggctattc ggcggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000957             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:18089:5719
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000957
VERSION     KCWK01000957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18089:5719"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66695.1"
                     /translation="DYYCQVWGMTSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          143 c          142 g           93 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccaatga tctgactcag
      121 ccgccctcgg tgtcagagtc cccaggacag acggccagga tcacctgtgg gggagacaaa
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgctggtc
      241 atctctggtg atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt ggggcatgac tagtgatcat ccggtattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000958             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:20343:13278
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000958
VERSION     KCWK01000958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20343:13278"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66696.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          142 c          132 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga attgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtatcaa cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000959             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:22769:3123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000959
VERSION     KCWK01000959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22769:3123"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66697.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          152 c          121 g          113 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gttcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattata acgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 caaactcata atttttgacg tcattaagcg gccctccggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcgacacgg cctccctgac catctctggg ctccgggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag aaataatttt ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000960             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:20909:12509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000960
VERSION     KCWK01000960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20909:12509"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66698.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          143 c          132 g           92 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacaga ctctgcgacc tcctatgaac tgactcagtc
      121 accctcagtg tcagcggcct cgggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa actgtgcact ggtaccagca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgat agtaaacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000961             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:14053:17049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000961
VERSION     KCWK01000961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14053:17049"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66699.1"
                     /translation="DYYCAAWDESLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          156 c          128 g          103 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgcg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctgggagca gctccaacat cggaagaaat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aaatcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc gccctggcca tcagcgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgaaagcc tgaggggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000962             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:16320:12206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000962
VERSION     KCWK01000962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16320:12206"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66700.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          148 c          130 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000963             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:16611:9457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000963
VERSION     KCWK01000963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16611:9457"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    50..383
                     /note="immunoglobulin light chain variable region"
     V_region        50..383
     V_segment       50..346
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <311..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66701.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       349..383
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>421
                     /gene="IGLC"
BASE COUNT           79 a          140 c          109 g           93 t
ORIGIN      
        1 acatgggctc ctcctcaccc tcctcgctca ctgcacaggg tcttgggctg aggttctgtt
       61 cacgcagccc cattctgtgt cggggtctcc ggggcagacg gtcaccatct cctgtacccg
      121 cagcagaggc aacattgaca atagttatgt gcagtggtac cagcagcgcc cgggcagtgc
      181 cccgaccaca gtgatttaca gagataacca aagagcctct ggggtccctg atcggttctc
      241 tggctccatc gacagctcct ccaactctgc ctccctcacc atctctgggc tgaagtctga
      301 ggacgaggct gactactact gtcagtctac tgatggcaac tacaatcggt tattcggagg
      361 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      421 g
//
LOCUS       KCWK01000964             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:16245:15831
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000964
VERSION     KCWK01000964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:16245:15831"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66702.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       394..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           87 a          141 c          136 g          102 t
ORIGIN      
        1 acatgggagc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactttac aggctctgtg gcctcctatg agttgcctca
      121 gccacgctca gtgtccgtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt aatagtgtgc attggtacca gcagaagcca ccgcgggccc ctgtattggt
      241 catctctgtt gatagcgaac ggccctcagg gatccctgag cgattctctg gttccagatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggataata tttataaata cgcggtattc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000965             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:7756:21523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000965
VERSION     KCWK01000965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7756:21523"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..409
                     /note="immunoglobulin light chain variable region"
     V_region        85..409
     V_segment       85..372
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66703.1"
                     /translation="DYYCQVWAMTSDHPVF"
     J_segment       375..409
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           87 a          142 c          125 g           93 t
ORIGIN      
        1 acatggggca ttgacggtgc ctcagccatg gcctggactt ttctcctcct cggcctcctt
       61 gcttactgca cagactctgc ggcctcctat gatctgactc agccaccctc ggtgtcagtg
      121 tccccaggac agacggccag gatcacctgt gggggagaca acattggaac tcaagttgtg
      181 aactggtacc agcagaagcc accgcaggcc cctgtgctgg tcatctatgc taataacgaa
      241 cggccctcag ggatccctga gcgattctct ggctccaaat cgaggaacac ggccaccctg
      301 accatcagcg gggtcgaggc cggggatgag gctgactatt actgtcaggt gtgggccatg
      361 actagtgatc atccggtatt cggcggaggg acccggctaa ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000966             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:21123:18532
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000966
VERSION     KCWK01000966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21123:18532"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..312
                     /note="immunoglobulin light chain variable region"
     V_region        8..312
     V_segment       8..275
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <231..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66704.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       276..312
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>350
                     /gene="IGLC"
BASE COUNT           73 a          103 c          104 g           70 t
ORIGIN      
        1 acatgggagt gtcggtgtcc ccaggacaga cagccagcat cacctgctct ggaaataaat
       61 tggggaatgt atatgcttac tggttccagc agaagccagg ccaggcccct gtagtggtca
      121 tctacaaaga taccaaccgg ccctcaggga tccctgagcg attctctggc tccgactcag
      181 ggaacacggc caccctgacc atcagcaggg tcgaggctgg ggatgaggcc gactattttt
      241 gtgctgcagc ctatggcagt ggcagcagct ggcagtgggt attcggcgga gggacccggc
      301 taatcgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000967             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:8956:22157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000967
VERSION     KCWK01000967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8956:22157"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..396
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66705.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       398..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           94 a          150 c          116 g          111 t
ORIGIN      
        1 acatggggtc tggagccagg gatcccttcc aatatcagca ccatggcctg gactctgttc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcacctgtgc ttccagcact
      181 ggagcagtca ccagtggtca ctctccacac tggttccagc agaaacctgg acaagccccc
      241 aagacactga tttataatac aaactacaga cactcctgga ctcctgcccg gttctcaggc
      301 tccctccttg ggggtaaagc tgccctgaca ctgtcaggtg cgcagcctga ggatgaggct
      361 gagtattatt gtttactgta ctatagtggt gctcagctgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000968             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:26274:11822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000968
VERSION     KCWK01000968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:26274:11822"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..389
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66706.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          152 c          121 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgag tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctctcagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccaggccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag tctgagcgga tacatcttcg gtgctgggac ccggctcgcc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000969             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:17962:12513
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000969
VERSION     KCWK01000969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17962:12513"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..449
                     /note="immunoglobulin light chain variable region"
     V_region        116..449
     V_segment       116..412
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66707.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       413..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           87 a          163 c          132 g          105 t
ORIGIN      
        1 acatgggggc agtgtggctg cctcagcaga gccctgagga gtctgcacca tggcctggac
       61 cccaatcctc ctcctcctcc tcactctcct ccttcactgc acagggtctc tctcccagcc
      121 tgtgctgact cagtcgccct ctgcctctgc ctccctggga gcctcggtca agttcacctg
      181 cactctgagc agtggacaca ggagctacac catcgcgtgg catcagcagc agcaagggaa
      241 ggcccctcga tacttgatgt ggcttaaaag tgatggcagc cacagcaagg gggacgggat
      301 ccctgatcgc ttctcaggct ccagctccgg ggctgagcgc tacctcacca tctccaacct
      361 ccagtctgag gatgaggctg attattattg tcagacgtgg gatattggca tttgggtgtt
      421 cggcggaggg acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01000970             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:11440:13128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000970
VERSION     KCWK01000970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11440:13128"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66708.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          142 c          134 g          101 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatcat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtgga ggagacaaca
      181 ttggaagtga ggttgtcaac tggtaccagc agaagccacc gcaggcccct gtgctggtca
      241 tctatgctga ttatgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcggag tcgaggccgg ggatgaggct gactattatt
      361 gtcaggtgtg ggacatttat attgaccatc cggtgttatt cggaggaggg acccgactga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01000971             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:18383:14137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000971
VERSION     KCWK01000971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18383:14137"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66709.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          159 c          117 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 ctgcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 ggttcaaatc agactcagat aaggaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ctcagcgaac acagggattt tacgcatctc tgggatccag tctgaggatg
      361 aggctgacta ctactgtgcc attgggcaca gcagcggtga ttacatcttc ggtgctggga
      421 cccgcctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000972             274 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:16578:5174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000972
VERSION     KCWK01000972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 274)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 274)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16578:5174"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..236
                     /note="immunoglobulin light chain variable region"
     V_region        7..236
     V_segment       7..199
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <167..>208
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66710.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       202..236
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        237..>274
                     /gene="IGLC"
BASE COUNT           52 a           84 c           75 g           63 t
ORIGIN      
        1 acatgggcag aagccaggga gcgctcccag gttattcctg tacttctact ccgactcaga
       61 caagcagctg ggacctgggg tccccgatcg cgtctctggc tccaaggaga cctcaagtaa
      121 cacagcgttt ttgctcatct ctgggctcca gcctgaggac gaggccgatt attactgtca
      181 ggtgtttgac agtagtgctg tcttattcgg aggagggacc cgactgaccg tcctaggtca
      241 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01000973             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18148:20981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000973
VERSION     KCWK01000973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18148:20981"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66711.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       389..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>461
                     /gene="IGLC"
BASE COUNT           90 a          144 c          131 g           96 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacagact ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtgaagt tgttaactgg taccagcaga agccaccgca ggcccctgtc ctggtcatct
      241 atgctaataa cgaacggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acacggccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtgggg cgttactagt gatcatccct tattcggagg agggacccgg ctgaccgtcc
      421 aaggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01000974             363 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:8893:16437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000974
VERSION     KCWK01000974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 363)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8893:16437"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..325
                     /note="immunoglobulin light chain variable region"
     V_region        8..325
     V_segment       8..285
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <247..>297
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66712.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       289..325
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        326..>363
                     /gene="IGLC"
BASE COUNT           77 a          102 c          107 g           77 t
ORIGIN      
        1 acatgggtga ctcagccacc ctcggtgtca gtgtccccag gaaagacggc caggatcacc
       61 tgtgggggag acaatattgg aagtgaagtt gtcaactggt accagcagaa gccaccgcag
      121 gcccctgtgg tggtcatcta tgctgattat gaacggccct cagggatccc tgagcgattc
      181 tctggctcca aatcagggaa cacggccacc ctgaccatca gcggagtcga ggccggggat
      241 gaggctgact attactgtca ggtttgggac atttatattg atcatccggt gttattcgga
      301 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      361 ccg
//
LOCUS       KCWK01000975             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:17319:19225
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000975
VERSION     KCWK01000975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17319:19225"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66713.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          155 c          117 g          112 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgactacca cgtacactgg tatcagcgga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggcctgg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaat acaggaattt tacacatctc tggtttccag tctgaggatg
      361 aggctgacta ttactgtgcc attggccacg gtagcggtga ctacatcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01000976             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:16782:11775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000976
VERSION     KCWK01000976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16782:11775"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66714.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       390..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          147 c          120 g          104 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagaactct gggtcctctc caccatggcc tggacccctc
       61 ccctgctcat cctcctcact ctctgcacag gttccgtggt ttcctctgag ctgactcagg
      121 agcctgcatt gtctgtggcc ttgggacata cagtcaggat gacctgccaa ggagacagcc
      181 tcaaaaccta ttatgcaagc tggtaccagc agaagccagg ccaggtccct gtgctggtca
      241 tctatggtaa caactaccgg ccctcaggga tcccaggccg attctctgtc tcctggtcag
      301 gaaacacagg ttccttgacc atcactgcga ctcaggtgga agatgaggct gactattact
      361 gtaagtcctg ggacagcagt ggtacccact acatcttcgg tggtgggacc cggctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01000977             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:10381:15066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000977
VERSION     KCWK01000977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:10381:15066"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66715.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       406..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          152 c          127 g          111 t
ORIGIN      
        1 acatgggggg cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag tgtctggggc gcccgggcag agggtcacca tctcctgcac
      181 tgggagcagc tccaacattg gagattatta tgtgcagtgg taccagcagc ttccaggaac
      241 ggcccccaaa ctcctcatct atgaaaatga taaaagaccc tcaggggttt ctgatcgatt
      301 ctctggctcc cagtctgatt cctcagcctc cctgaccatc actggactcc agtctgagga
      361 tgaggctgat tattactgcc agtcctatga cagcagcttg agtgttgtgt tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01000978             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:7089:22183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000978
VERSION     KCWK01000978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7089:22183"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..312
                     /note="immunoglobulin light chain variable region"
     V_region        8..312
     V_segment       8..273
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66716.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       275..312
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>350
                     /gene="IGLC"
BASE COUNT           73 a          105 c           94 g           78 t
ORIGIN      
        1 acatgggggg agcatcggcc agactcccct gcaccctgag cagtgacctc agtgttggta
       61 gtaaaaacat gtactggtac caacagaagc cagggagcgc tcccaggtta ttcctgtact
      121 actactccga ctcagacaac cagctgggac ctggggtccc caatcgagtc tctggctcca
      181 aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct gaggacgagg
      241 ccgattattt ctgccaggtg tttgacagta gtgttgtgtt cttcggagga gggacccgac
      301 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01000979             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:15425:7960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000979
VERSION     KCWK01000979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15425:7960"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66717.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       412..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          160 c          125 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaatat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct cccagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gacgatagcc tgcgcggcta tatcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01000980             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:9169:20329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000980
VERSION     KCWK01000980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9169:20329"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66718.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          148 c          130 g           97 t
ORIGIN      
        1 acatgggggt gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000981             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13073:10882
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000981
VERSION     KCWK01000981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13073:10882"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66719.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          161 c          112 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttagtgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000982             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:15705:13855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000982
VERSION     KCWK01000982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15705:13855"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66720.1"
                     /translation="EYYCCSYTTSSTYVF"
     J_segment       407..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          157 c          117 g          115 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggatc
      181 cagtagtgac attggtaatt ctaactctgt ctcctggtac cagaagcacc caggcaaagc
      241 ccccaaagtc atgatttatg gtgtcagtaa tcgggcctca ggggtctctg atcgcttctc
      301 tggctccaag tctgccaacg cggcctccct gaccatctct gggctccagc ctgaggacga
      361 ggctgaatat tactgttgtt catatacaac cagtagtact tacgttttcg gtgctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01000983             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:14905:19014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000983
VERSION     KCWK01000983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14905:19014"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66721.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          144 c          132 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000984             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:15944:14088
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000984
VERSION     KCWK01000984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15944:14088"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..446
                     /note="immunoglobulin light chain variable region"
     V_region        98..446
     V_segment       98..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66722.1"
                     /translation="DYYCQVYDSSAGVLF"
     J_segment       409..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          163 c          123 g          109 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt agtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtc
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caactaacac agcgtttttg ctcatctctg gactccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtatgacagt agtgctggtg tgttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01000985             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:24135:12521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000985
VERSION     KCWK01000985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:24135:12521"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    41..330
                     /note="immunoglobulin light chain variable region"
     V_region        41..330
     V_segment       41..293
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <255..>302
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66723.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       294..330
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        331..>368
                     /gene="IGLC"
BASE COUNT           77 a          112 c           95 g           84 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggaagagt gtctccatct
       61 cctgttctgg aagcagctcc aacatcggaa gtcatagtgt ctcctggtac cggcacctcc
      121 caggaacagc tcccaaactc ctcatctatt atagtgatca acgagcctca ggtgtctctg
      181 accgattctc tggctccaag tctggcacgt cagcctccct ggccatcagt gggctccaga
      241 ccgaggatga ggctgattat tactgcgcag catgggatga taacctgagc ggttacatct
      301 tcggttctgg gacccgactc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      361 tgttcccg
//
LOCUS       KCWK01000986             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:15515:9729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000986
VERSION     KCWK01000986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15515:9729"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66724.1"
                     /translation="DYSCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          163 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atctactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tcctgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01000987             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:13433:6621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000987
VERSION     KCWK01000987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13433:6621"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..390
                     /note="immunoglobulin light chain variable region"
     V_region        104..390
     V_segment       104..351
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <318..>362
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66725.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       353..390
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        391..>428
                     /gene="IGLC"
BASE COUNT           79 a          133 c          113 g          103 t
ORIGIN      
        1 acatggggga ggcagcactc aggacagtct ccagcatggc ctggtctctc cttctcactc
       61 tgctggttca ctgcacaggg tcctgggccc agtctgtgct gacgcagagg gttaccatct
      121 cctgcactgg gagcagctcc aacatcgggg cgggttttta tgtgtcctgg taccagcagt
      181 tccctggaac agcccccaaa ctcctcatct ttgaaaataa taagcgaccc tcaggggttt
      241 ctgaccgatt ctctggctcc aagtctggtt cctcagcctc cctgaccatc actggactcc
      301 agtctgagga tgaggctgat tattactgct catcatggga aagcagcctg aattgggttt
      361 tcggcggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      421 tcttcccg
//
LOCUS       KCWK01000988             453 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:14036:5003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000988
VERSION     KCWK01000988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 453)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:14036:5003"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..415
                     /note="immunoglobulin light chain variable region"
     V_region        91..415
     V_segment       91..376
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <340..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66726.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       381..415
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>453
                     /gene="IGLC"
BASE COUNT          104 a          135 c          117 g           97 t
ORIGIN      
        1 acatggggga ggaagagctc tgggtgtctc accatgacct ggaccactgt tctgctcccc
       61 tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc accctcagtg
      121 tctgtgtccc caggacagac ggccaggatc acctgctctg gagaaatact ggcaaaaaaa
      181 tatactcagt ggttccagca gcagccaggc caggcccctt tcctggtgat atataaagac
      241 agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg gacaacaatt
      301 accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg tcaatcagta
      361 gacagcagtg gaaatcttcc gttattcgga ggagggaccc ggctgaccgt cctaggtcag
      421 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000989             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:8860:20757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000989
VERSION     KCWK01000989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:8860:20757"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66727.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          147 c          132 g           98 t
ORIGIN      
        1 acatgggggt gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccgatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta agagtgtgca ctggtaccag cacaagccac cgcaggcccc tatcctggtc
      241 atctattatt ataccgaacg gccctcggcg atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacactac tattgatcat ggctttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000990             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:14557:2531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000990
VERSION     KCWK01000990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14557:2531"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66728.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           91 a          146 c          128 g           97 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtcaaa gtgtgcactg gtaccagcac aagccaccgc aggcccctgt actggtcatc
      241 ttttattata ccgaacggcc ctcaggaatc cctgagcgat tctctggctc caaatcaggg
      301 aataccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acacaactat tgatcacggc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01000991             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:10491:4093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000991
VERSION     KCWK01000991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10491:4093"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66729.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           82 a          156 c          127 g          108 t
ORIGIN      
        1 acatggggtg gggtctcagg aggcagcgct ctcgggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcagtct gccctgactc
      121 agcctccctc agtgtccaag tctcttggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat tggtggttat gatggcgtct cctggtacca gcagcactca gggacagccc
      241 ccagactcct gatttatgat gtcactaagc ggccctcagg ggtctcggat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctca ccatctctgg gctccagact gaggacgagg
      361 ctgattatta ttgttgctca tataggagtg gaaacacttg gctattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01000992             356 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:14119:5736
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000992
VERSION     KCWK01000992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 356)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 356)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..356
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14119:5736"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..318
                     /note="immunoglobulin light chain variable region"
     V_region        8..318
     V_segment       8..282
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <246..>290
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66730.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       286..318
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        319..>356
                     /gene="IGLC"
BASE COUNT           78 a          103 c          105 g           70 t
ORIGIN      
        1 acatggggac tcagtcattc tcagtgtcag cggcctcagg acagccggcc aggatcacct
       61 gtgggggaga caacattgga actaaaactg tgcactggta ccaacagaag ccaccgcagg
      121 gccctgtatt ggtcatcttt gctgatagta gacggccctc agggatccct gagcgattct
      181 ctggctccaa ctcagggaac accgccaccc tgaccatcag cagggtcgag gccggggatg
      241 aggctgacta ttactgtcag gtgtgggaca gtagtagtaa atggatattc ggcgggggga
      301 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01000993             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:5761:7833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000993
VERSION     KCWK01000993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:5761:7833"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..395
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66731.1"
                     /translation="DYYCHSADGNYRIF"
     J_segment       399..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           86 a          158 c          126 g           99 t
ORIGIN      
        1 acatgggggt gactcagaaa gcagagcctg gggcgtctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcagtcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagcattgat agggaatatg tgcagtggta ccagcagcgc ccgggcagtg cccccaccac
      241 agtgatttac aaagataacc aaagaccctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcgc catctctggg ctaaagtctg aggacgaggc
      361 tgactactac tgtcactctg ctgatggcaa ctacaggata ttcggcggag ggacccggct
      421 caccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000994             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:9237:13835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000994
VERSION     KCWK01000994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:9237:13835"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66732.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           90 a          160 c          121 g          110 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttgga aataaaaaca tatactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtcatac agcgtttttg ctcatttctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtatgacgat agtgctgtgt tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01000995             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:9201:6180
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000995
VERSION     KCWK01000995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9201:6180"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66733.1"
                     /translation="DYYCQVWGSRSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          149 c          135 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gtctctgcga cctcctatga actgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccaggg tcacctgtgg ggcaggtaac
      181 attggaagta attttgttca ctggtaccag cagaagccac cgcaggcccc tgttcaggtc
      241 atctatgcag ataacagacg gccctcaggg atccctgagc gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt ggggcagtcg tagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000996             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:18557:10812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000996
VERSION     KCWK01000996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18557:10812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..400
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66734.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           91 a          152 c          121 g          111 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctcctct
       61 cctcctcacc cttctcattc acttcacagt tccagggtcc tgggcccagt ctgtgctgac
      121 gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag
      181 cagctccaac attggagatt attttgtgca gtggtaccag caccttctag gaacggcccc
      241 caaactcctc atctatgaaa ataataagcg accctcaggg atttctgatc gattctctgg
      301 ctcccagtct ggaacctcag cctccctgac catcactgga ctccagtctg aggatgaggc
      361 tgattattac tgccagtcct atgacagcag tttgattgct gtgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01000997             299 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:21838:15012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000997
VERSION     KCWK01000997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 299)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21838:15012"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..261
                     /note="immunoglobulin light chain variable region"
     V_region        6..261
     V_segment       6..224
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>233
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66735.1"
                     /translation="DYSCAIGHSSGPYIF"
     J_segment       225..261
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        262..>299
                     /gene="IGLC"
BASE COUNT           67 a           96 c           71 g           65 t
ORIGIN      
        1 acatgggcta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
       61 tgagttacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      121 gatccaaaaa tacttcaacg aacacaggca ttttacacat ctctgggctc cagtctgagg
      181 atgaggctga ctattcctgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      241 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01000998             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:9259:18155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000998
VERSION     KCWK01000998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9259:18155"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66736.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          160 c          113 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01000999             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:13552:12360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01000999
VERSION     KCWK01000999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13552:12360"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..398
                     /note="immunoglobulin light chain variable region"
     V_region        74..398
     V_segment       74..360
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <323..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66737.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       366..398
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>436
                     /gene="IGLC"
BASE COUNT           83 a          138 c          127 g           88 t
ORIGIN      
        1 acatggggcc tcagccatgg cctggacttt tctcctcctc ggcctccttg cttactgcac
       61 aggctctgcg gcctcctatg atctgactca gccaccctcg gtgtcagtgt ccccaggaca
      121 gacggccagg atcacctgcg ggggagacaa gattggaagt gaagttgtga actggtacca
      181 gcagaagcca gcgcacgccc ctgtgctggt catctatgct aatagcgaac ggccctcagg
      241 gatccctgag cgattctctg gctccaaatc agggaacacg gccaccctga ccatcagcgg
      301 ggtcgaggcc gggggtgagg ctgactatta ctgtcaggtg tgggacatgc gtagtgatca
      361 accgctattc ggcggaggga cccggctaac cgtcctaggt cagcccaagg ctgccccctc
      421 ggtcactctc ttcccg
//
LOCUS       KCWK01001000             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:6302:16827
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001000
VERSION     KCWK01001000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:6302:16827"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..434
                     /note="immunoglobulin light chain variable region"
     V_region        86..434
     V_segment       86..397
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66738.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       398..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           91 a          158 c          114 g          109 t
ORIGIN      
        1 acatgggggg aaagaggctg tgtccaccat ggcctggact cctctcctcc tcctgctcct
       61 ctctcactgc acaggttccc tctccaagcc tatgctgact cagccggcct ccctctcagc
      121 atctcctgga gcatcagcca gtctcacatg caccttcagc ggtggcatca atgttggtgt
      181 ctaccacata cactggtacc aactgaagcc agggagtccc ccccggtatc ttctgaggta
      241 caaatcagac tcagataagg gccagggctc tggagtcccc agccgcttct ctggatccag
      301 taatgcttca gcgaacacag ggattttacg catctctggg ctccagtctg aggatgaggc
      361 tgactattac tgtgccattg gacacagcag cggtccttac atcttcggtg ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01001001             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:18078:9122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001001
VERSION     KCWK01001001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:18078:9122"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66739.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          153 c          121 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaccg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001002             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:22751:18159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001002
VERSION     KCWK01001002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22751:18159"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66740.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          160 c          123 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gaaataaaaa cttatactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtcat acagcgtttt tgctcatttc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgacg atagtgctgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001003             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:22817:16714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001003
VERSION     KCWK01001003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22817:16714"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66741.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           84 a          154 c          122 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccgg gaagagtgtc tccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 gtctattata gtgatcaacg agcctctggt gtctctgacc gattctctgg cgctcagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagcggt tacatcttcg gtgctgggac ccggctcgcc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001004             515 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:20140:14619
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001004
VERSION     KCWK01001004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 515)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 515)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..515
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20140:14619"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    153..477
                     /note="immunoglobulin light chain variable region"
     V_region        153..477
     V_segment       153..440
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <402..>449
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66742.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       441..477
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        478..>515
                     /gene="IGLC"
BASE COUNT          101 a          169 c          133 g          112 t
ORIGIN      
        1 acatgggggc tcagaagcag aactctgggt cctctccacc atggcctgga cccctcccct
       61 gctcatcctc ctcactctct gcacaggtgc tgcctcccag tgctcagccc ccacagaacc
      121 agggatcggc ccagccctga ggttccgtgg tttcctctga gctgactcag gagcctgcat
      181 tgtctgtggc cttgggacat acagtcagga tgacctgcca aggagacagc ctcagaacct
      241 attatgcaag ctggtaccag cagaagccag gccaggtccc tgtgctggtc atctatggta
      301 acaactaccg gccctcaggg atcccaggcc gattctctgt ctcctggtca ggaaacacag
      361 gttccttgac catcactgcg gctcaggtgg aagatgaggc tgactattat tgtaagtcct
      421 gggacagcag tggtacccat tacatcttcg gtgctgggac ccggctcacc gtcctaggtc
      481 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001005             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:5719:4550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001005
VERSION     KCWK01001005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5719:4550"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66743.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       412..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           89 a          154 c          130 g          114 t
ORIGIN      
        1 acatggggga gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tttcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg agcagctcca acattggagg ttattatgtg cagtggtacc agcagcttcc
      241 agggacggcc cccaaactcc tcatctatga aaatgataaa cgaccctcag gggtttctga
      301 tcgattctct ggctcccagt ctgattcctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agcttgagtg ttgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01001006             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:16882:17922
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001006
VERSION     KCWK01001006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16882:17922"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66744.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       388..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           93 a          141 c          130 g           94 t
ORIGIN      
        1 acatgggggt ctcaggaggc agcattgacg gtgcctcagc catggcctgg acccttctcc
       61 tcctcggcct cctcgcttac tgcacaggct ctgcgacctc ctatgaattg actcagtcac
      121 cctcagtgtc agcggcctca ggacagccgg ccaggatcac ctgtggggga gacaacattg
      181 gaactaaaac tgtgcactgg taccaacaga agccaccgca gggccctgta ttggtcatct
      241 ttgctgatag tagacggccc tcagggatcc ctgagcgatt ctctggctcc aattcaggga
      301 acaccgccac cctgaccatc agcagggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cagtagtagt aaatggatat tcggcggggg gacccggcta accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001007             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:19036:7793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001007
VERSION     KCWK01001007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19036:7793"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..258
                     /note="immunoglobulin light chain variable region"
     V_region        8..258
     V_segment       8..221
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <177..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66745.1"
                     /translation="DYHCAAGYGSGSSWQWVF"
     J_segment       222..258
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           61 a           89 c           93 g           53 t
ORIGIN      
        1 acatgggggg gaatgtatac gcctactggc accagcagaa gccaggccag gcccctgtat
       61 tggtcatcta caaagataag aaccggccct cagggatccc tgagcgattc tctggctcca
      121 gctcagggaa cacggccacc ctgaccatca gtagggtcga ggctggggat gaggccgact
      181 atcactgtgc tgcaggctat ggcagtggga gcagctggca gtgggtattc ggcggaggga
      241 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001008             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:21775:9846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001008
VERSION     KCWK01001008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:21775:9846"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66746.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           89 a          162 c          120 g          108 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcgtcaatg
      181 tgggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacca gtcagactca aggaagcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc tgttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccctctggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001009             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:10512:11089
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001009
VERSION     KCWK01001009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:10512:11089"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66747.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT          108 a          136 c          124 g           99 t
ORIGIN      
        1 acatgggggg ctgtggttct aggaggaaga gctctgggtg tctcaccatg acctggacca
       61 ctgttctgct cccctttctc actctctgca caggctctga ggcctcctat gacctgacac
      121 agccaccctc agtgtcagtg tccccagggc agacggccag gatcacctgc tctggagaaa
      181 tactggcaaa aaaatatact cagtggttcc agcagaagtc aggccagggc cctagactgg
      241 tgatatataa agacagtgag aggccctcag ggatccctga gcgattctct agctccagtt
      301 cagggacaac agtcaccttg accatcagcg gggcccagac agaagatgag gctgactatt
      361 actgtcaatc agcagacaga agtcctaatc atgtgttttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001010             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:25172:21652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001010
VERSION     KCWK01001010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:25172:21652"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66748.1"
                     /translation="DYYCSAWDSSLTGGLF"
     J_segment       406..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          156 c          123 g          106 t
ORIGIN      
        1 acatggggag cttcagctgt ggctagagaa gacaggactc aggacaatct ccagcatggc
       61 ctgcttccct ctcatcctca ccgtcctcac tcactgtgca ggatcctggg cccagtctgt
      121 gctgactcaa ccaccctcag cgtctggggc ccccgggcag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaatta tgtatactgg taccagcagt tctcagggaa
      241 ggcccccaaa ctcctcatcc ataataataa tcaccgaccc tcaggggtcc ctgatcgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agtccgagga
      361 tgaggctgat tattactgct cagcgtggga tagcagtctg accggtggct tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01001011             372 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:4884:12782
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001011
VERSION     KCWK01001011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 372)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4884:12782"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..334
                     /note="immunoglobulin light chain variable region"
     V_region        13..334
     V_segment       13..298
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>306
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66749.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       302..334
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        335..>372
                     /gene="IGLC"
BASE COUNT           82 a          110 c          107 g           73 t
ORIGIN      
        1 acatgggcga cctcctatga attgactcag tcaccctcag tgtcagcggc ctcaggacag
       61 ccggccagga tcacctgtgg gggagacaac attggaacta aaactgtgca ctggtaccaa
      121 cagaagccac cgcagggccc tgtattggtc atctttgctg atagtagacg gccctcaggg
      181 atccctgagc gattctctgg ctccaactca gggaacaccg ccaccctgac catcagcagg
      241 gtcgaggccg gggatgaggc tgactattac tgtcaggtgt gggacagtag tagtaaatgg
      301 atattcggcg gggggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      361 actctcttcc cg
//
LOCUS       KCWK01001012             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:22150:5339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001012
VERSION     KCWK01001012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22150:5339"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    68..416
                     /note="immunoglobulin light chain variable region"
     V_region        68..416
     V_segment       68..376
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66750.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       379..416
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           88 a          152 c          106 g          108 t
ORIGIN      
        1 acatgggacc atggcctgga ctcctctcct cctcctgctc ctctctcact gcacaggttc
       61 cctctccaag cctatgctga ctcagccggc ctccctctca gcatctcctg gagcatcagc
      121 cagtctcaca tgcaccttca gcggtggcat caatgttgct ggctaccaca tacactggta
      181 tcagcagaag ccagggagtc ccccccggta tcttctgagg tacaaatcag actcagataa
      241 gggcctgggc tctggagtcc ccagccgctt ctctggatcc aaagatgctt cagcgaatac
      301 agggatttta cacatctctg gtttccagtc tgaggatgag gctgactatt actgtgccat
      361 tggccacggc agcggtgatt acatcttcgg tactgggacc cggctcaccg tcctaggtca
      421 gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001013             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:25698:7188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001013
VERSION     KCWK01001013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:25698:7188"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..400
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66751.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       403..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          159 c          119 g          107 t
ORIGIN      
        1 acatggggag ggaaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccca gcctgtgctg acccagccaa cctccctctc
      121 agcatctccg ggagcatcag ccagactcag ctgcaccttg agcagtggcg tcaatgtggg
      181 tagttacagc atattctggt accagcagaa gccagggagt cctccccggt accttctgta
      241 ctaccagtca gactcaagga agcaccaggg ctctggagtc cccagccgct tctctggatc
      301 caaagatgct tcagccaatg cagggctgtt actgatctct gggctccagt ctgaagatga
      361 ggctgactat tactgtgccc tatggcacag cagcgcttct tgcatcttcg gtggtgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001014             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:27163:5788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001014
VERSION     KCWK01001014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:27163:5788"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66752.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>430
                     /gene="IGLC"
BASE COUNT           87 a          122 c          129 g           92 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 agcctcggtg tcagtgtccc cgggacagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtaaa aatgtgcact ggtaccagca ggagccaccg caggcccctg tgttggtcat
      241 cttttatgat aacaaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacatcgcc accctgacca tcagcgaggc cgaggccggg gatgaggctg actattactg
      361 tcagctgtgg gacagtagtg ttgatcatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag
//
LOCUS       KCWK01001015             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:16814:11647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001015
VERSION     KCWK01001015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16814:11647"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66753.1"
                     /translation="DYYCSSYAGSNILFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          151 c          121 g          113 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaag
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagtaatatt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001016             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:9854:14195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001016
VERSION     KCWK01001016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9854:14195"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66754.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          166 c          122 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattcgt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagccc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001017             495 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:20282:10992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001017
VERSION     KCWK01001017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 495)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20282:10992"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..457
                     /note="immunoglobulin light chain variable region"
     V_region        112..457
     V_segment       112..418
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <388..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66755.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       420..457
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        458..>495
                     /gene="IGLC"
BASE COUNT           89 a          169 c          125 g          112 t
ORIGIN      
        1 acatgggggc agcccaaccc tgggtctgtg gcctcagagg tagccgtgtc caccatggcc
       61 ctgactcctc tcctcctcct gctcctctct cactgcacag gttccctctc ccagcctgtg
      121 ctgactcagc caccctccct gtctgcatcc ccgggagcat cggccagact cccctgcacc
      181 ctgagcagtg acctcagtgt tggtagtaaa aacatgtact ggtaccagca gaagccaggg
      241 agcgctccca ggttattcct gtactactac tccgactcag acaagcagct gggacctggg
      301 gtccccaatc gagtctctgg ctccaaggag acctcaagta acacagcgtt tttgctcatc
      361 tctgggctcc agcctgagga cgaggccgat tatttctgcc aggtgtttga cagtagtgtt
      421 gtgttcttcg gaggagggac ccgactgacc gtcctaggtc agcccaaggc tgccccctcg
      481 gtcactctct tcccg
//
LOCUS       KCWK01001018             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:7322:11643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001018
VERSION     KCWK01001018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7322:11643"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66756.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          153 c          119 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgagctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctcct gctctggaag cagctccaat
      181 attggaagta attctgtata ctggtaccag catttcccag gaacggcccc caaactcctc
      241 atctattata gtaatcagcg accctcaggg gtccctgacc gagtctctgg ctctaagtcg
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgacag cctgagaagt ccgctattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001019             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:2787:13362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001019
VERSION     KCWK01001019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:2787:13362"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..396
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66757.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           93 a          155 c          118 g          108 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcatctcctg gaacatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgtt
      181 ggctaccaca tacactggta ccagcagaag ccagggagtc ctccccggta tcttctgaga
      241 tacaaatcgg actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagcgaacgc agggatttta cgcatctctg gactccagtc tgaggatgag
      361 gctgactatt actgtgccat tgggcacagc agcggtgatt acatcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001020             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:24911:16753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001020
VERSION     KCWK01001020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24911:16753"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..401
                     /note="immunoglobulin light chain variable region"
     V_region        78..401
     V_segment       78..364
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <327..>374
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66758.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       366..401
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>440
                     /gene="IGLC"
BASE COUNT           86 a          141 c          119 g           94 t
ORIGIN      
        1 acatgggcgg tgcctcagcc atggcctgga cttttctcct cctcggcctc cttgcttact
       61 gcacaggctc tgcggcctcc tatgatctga ctcagccacc ctcggtgtca gtgtccccag
      121 gacagacggc caggatcacc tgtgggggag acaacattgg aagtcaaagt gtgcactggt
      181 accagcacaa gccaccgcag gcccctgttc tggtcatctt ttattatacc gaacggccct
      241 caggaatccc tgagcgaatc tctggctcca aatcagggaa caccgccacc ctgaccatca
      301 gcggggtcga ggccggggat gaggctgact attactgtca ggtgtgggac acaagtcttg
      361 atcacggctt atttggagga gggacccggc tgaccgtcct aagtcagccc aaggctgccc
      421 cctcggtcac tctcttcccg
//
LOCUS       KCWK01001021             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:7007:14914
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001021
VERSION     KCWK01001021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7007:14914"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66759.1"
                     /translation="DYSCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          160 c          115 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccccatacac tggtaccaac agaagccagg gagtcctccc cggtatcttc
      241 tgacatacaa atcagactca gataggggcc aggcctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagca aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattcctgt gccattggac acagcagcgg tgattacatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001022             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:24148:9209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001022
VERSION     KCWK01001022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:24148:9209"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66760.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          141 c          132 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagt ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tgctggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccgactgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001023             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:15889:4495
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001023
VERSION     KCWK01001023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15889:4495"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66761.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          142 c          136 g          101 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtcaac tggtaccaac agaagccacc gcaggcccct gtggtggtca
      241 tctatgctga ttatgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcggag tcgcggccgg ggatgaggct gactattact
      361 gtcaggtttg ggacatttat actgatcatc cggtgttgtt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001024             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:18032:4140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001024
VERSION     KCWK01001024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18032:4140"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66762.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          150 c          136 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta aatatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
      241 atctatgctg ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactcc
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg ggtatgaggc tgactatttc
      361 tgtcaggtgt gggacgatag tagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001025             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:11776:20911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001025
VERSION     KCWK01001025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11776:20911"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66763.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       400..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          156 c          126 g          102 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcgtctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttggtct gaggttctgt tcacgcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgtaccc gcagcagagg
      181 caacattgac aatagttatg tgcagtggta ccagcagcgc ccgggcagtg ccccgaccac
      241 agtgatttac agagataacc aaagagcctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctggg ctgaagtctg aggacgaggc
      361 tgactactac tgtcagtcta ctgatggcaa ctacaatcgg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001026             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:20505:17992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001026
VERSION     KCWK01001026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20505:17992"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66764.1"
                     /translation="DYYCSSYGGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          152 c          121 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atcacctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atggaggcag caatacttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001027             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15202:11396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001027
VERSION     KCWK01001027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15202:11396"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66765.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          148 c          130 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccgatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta agagtgtgca ctggtaccag cacaagccac cgcaggcccc tatcctggtc
      241 atctattatt ataccgaacg accctcggcg atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacactac tattgatcat ggctttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001028             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:21204:8141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001028
VERSION     KCWK01001028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:21204:8141"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66766.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          152 c          123 g          104 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaacag tgtcgccatc tcctgttctg gaagcagctc
      181 caacatcgga agtcatagtg tatcctggta ccagcagctc ccaggaacag ctcccaaact
      241 cctcatctat tatgatgatc aacgagcctc gggtgtctct gaccgattct ctggctccag
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcatgggatg atagcctgag aggttacatc ttcggtgatg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001029             382 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:25427:14210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001029
VERSION     KCWK01001029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 382)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:25427:14210"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    31..344
                     /note="immunoglobulin light chain variable region"
     V_region        31..344
     V_segment       31..305
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <272..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66767.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       307..344
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>382
                     /gene="IGLC"
BASE COUNT           75 a          116 c          104 g           87 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca gcatctgggg cccccgggca
       61 gagggtcacc atctcctgca ctgggagcag ctccaacatc ggggcgggtt tttatgtttc
      121 ctggtaccag cagttcccag gaacagcccc caaactcctc atctttgaaa ataataagcg
      181 accctcaggg gtttctgacc gattctctgg ctccaagtct ggttcctcag cctccctgac
      241 catcactgga ctccaatctg aggatgaggc tgattattat tgttcatcat gggagagcag
      301 cctgaattgg gtattcggcg gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc
      361 cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001030             285 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:9074:8236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001030
VERSION     KCWK01001030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 285)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:9074:8236"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..247
                     /note="immunoglobulin light chain variable region"
     V_region        8..247
     V_segment       8..210
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <172..>219
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66768.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       211..247
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        248..>285
                     /gene="IGLC"
BASE COUNT           58 a           89 c           72 g           66 t
ORIGIN      
        1 acatggggta ataatgtgtc ctggtaccag cacctcccag gaacagctcc caaactcctc
       61 atctattata atgatcaacg aggctcaggt gtctctgacc gattctctgg ctccaagtct
      121 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      181 tgcgcagcgt gggatgatag gctgagcagt tacatcttcg ctgctgggac ccggctcacc
      241 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001031             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:14758:13431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001031
VERSION     KCWK01001031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14758:13431"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66769.1"
                     /translation="DYYCAAWDDRLRGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          156 c          126 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaac agtgtcgcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatgatga tcaacgagcc tcgggtgtct ctgaccgatt
      301 ctctggctcc aggtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatcgcctg agaggttaca tcttcggtga
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01001032             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:2157:10864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001032
VERSION     KCWK01001032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:2157:10864"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66770.1"
                     /translation="DYYCCSRSTSSTYVF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           82 a          162 c          117 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac gttggtggtt ataactctgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaagtc atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagt ctgaggacga
      361 ggctgattat tactgttgtt cacgttcaac cagtagcact tacgtcttcg gtcctgggac
      421 ccggctcacc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001033             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:13219:16932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001033
VERSION     KCWK01001033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13219:16932"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..410
                     /note="immunoglobulin light chain variable region"
     V_region        80..410
     V_segment       80..373
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <335..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66771.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       374..410
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>448
                     /gene="IGLC"
BASE COUNT           86 a          148 c          109 g          105 t
ORIGIN      
        1 acatgggggg acaatctcca gcatggcctg gttccctctc ctcctcaccc tcctcactca
       61 ctgtgcaggg tcctgggccc agtctgtgtt gactcagcct ccctcagcgt ctgaggccgc
      121 cgggaagagt gtcaccatct cctgttctgg aagcagctcc aacatcggaa gtaatagtgt
      181 atcctggtac caacaactcc cagaaacggc tcccaaactc ctcatgtatt ataatcatcg
      241 gcgagcctca ggtgtctctg accgattctc tggctccaag tctggcactt cagcctccct
      301 ggccatcagt gggctccaga ccgaggatga ggctgattat tactgcgcag tatgggatga
      361 tagcctgacc ggttacatct tcggtactgg gacccggctc accgtcctag gtcagcccaa
      421 ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01001034             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:17770:2790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001034
VERSION     KCWK01001034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17770:2790"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..433
                     /note="immunoglobulin light chain variable region"
     V_region        112..433
     V_segment       112..397
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66772.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       401..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           93 a          148 c          134 g           96 t
ORIGIN      
        1 acatggggct gccctgtctg ggtctcagga ggcagcattg acggtgcctc agccatggcc
       61 tggacccttc tcctcctcgg cctcctcgct tactgcacag actctgcgac ctcctatgaa
      121 ctgactcagt caccctcagt gtcagcggcc tcgggacagc cggccaggat cacctgtggg
      181 ggagacaaca ttggaactaa aactgtgcac tggtaccagc agaagccacc gcagggccct
      241 gtattggtca tctttgctga tagtaaacgg ccctcaggga tccctgagcg attctctggc
      301 tccaactcag ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct
      361 gactattact gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001035             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:21439:7558
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001035
VERSION     KCWK01001035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21439:7558"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66773.1"
                     /translation="DYYCATWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          156 c          126 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcgggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgctacatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001036             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:12770:21123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001036
VERSION     KCWK01001036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12770:21123"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66774.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          164 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaacc cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001037             329 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:26086:16688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001037
VERSION     KCWK01001037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 329)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:26086:16688"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..291
                     /note="immunoglobulin light chain variable region"
     V_region        9..291
     V_segment       9..254
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <216..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66775.1"
                     /translation="DYYCQSSHSRVNHPFF"
     J_segment       261..291
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>329
                     /gene="IGLC"
BASE COUNT           80 a           91 c           92 g           66 t
ORIGIN      
        1 acatgggggg acagacggcc aggatcacct gctctggaga aacactggca aaaaaatatg
       61 ctcagtggtt ccagcagaag ccaggccagg cccctgtgtt ggtgatatat aaagacagtg
      121 agaggccctc agggatccct gagcgattct ctagctccag ttcagggaca acagttacct
      181 tgaccatcag tggggcccag gcagaagatg aggctgacta ttactgtcaa tcatcgcaca
      241 gcagggttaa tcatccgttt ttcggaggag ggacccggct gaccgtccta ggtcagccca
      301 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001038             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:16897:14875
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001038
VERSION     KCWK01001038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16897:14875"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66776.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          157 c          123 g          105 t
ORIGIN      
        1 acatgggggc tgtggctcag gaagcagagc ctggagcatc tccaccatgg cctgggctcc
       61 actcctcctc accctcctcg ctcactgcac agggtcttgg gctgaggttg tgttcactca
      121 gccccattct gtgtcggggt ctccggggca gacggtcacc atctcctgca cccgcagcag
      181 tggcagcatt gacaacggct ttgtgtactg gtaccagcag cggccgggca acgctcccac
      241 cactgtgatt tacaaagata accaaagacc ctctggggtc cctgatcggt tctctggctc
      301 catcgacagc tcctccaact ctgcctccct caccatctct ggactgaaat ctgaggacga
      361 ggctgactat tactgtcagt cttatgacag cagcagtgta ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001039             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:10030:11204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001039
VERSION     KCWK01001039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10030:11204"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66777.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          148 c          131 g           97 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt caaagtgtgc actggtacca gcacaagcca ccgcaggccc ctgttctggt
      241 catcttttat tataccgaac ggccctcagg aatccctgag cgaatctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacacaa gtcttgatca cggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001040             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:3513:18652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001040
VERSION     KCWK01001040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:3513:18652"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    59..383
                     /note="immunoglobulin light chain variable region"
     V_region        59..383
     V_segment       59..334
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <308..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66778.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       346..383
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>421
                     /gene="IGLC"
BASE COUNT           83 a          134 c          115 g           89 t
ORIGIN      
        1 acatgggtgg acccttctcc tcctcggcct cctcgctcac tgcacaggct ctgcgacctc
       61 ctttgagctg actcagccac cctcggtgtc agcggcctca ggacagacgg ccaggatcac
      121 ctgtggggga gacaacattg gaattaaatt tgtccactgg taccagcaga agccagcgca
      181 ggcccctgtg aaggtcatct atgctgatga caaacggccc tcagggatcc ctgagagatt
      241 ctctggctcc aattcaggga acaccgccac cctgaccatc agcggggtcg aggccgggga
      301 tgaggctgac tattcctgtc aggtgtggga cagtgagact gattattaca tcttcggttc
      361 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      421 g
//
LOCUS       KCWK01001041             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:19249:20722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001041
VERSION     KCWK01001041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19249:20722"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..289
                     /note="immunoglobulin light chain variable region"
     V_region        8..289
     V_segment       8..250
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <214..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66779.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       252..289
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           67 a           97 c           82 g           81 t
ORIGIN      
        1 acatgggggg tcaccatctc ctgcactggg agcagctcca acattggagg ttattatgtg
       61 cagtggtacc agcagcttcc aggaacggcc cccaaactcc tcatctatga aaatgataaa
      121 cgaccctcag gggtttctga tcgattctct ggctcccagt ctgattcctc agcctccctg
      181 accatcactg gactccagtc tgaggatgag gctgattatt actgccagtc ctatgacagt
      241 agcttgagtg ttgtgttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      301 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001042             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:18249:10678
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001042
VERSION     KCWK01001042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:18249:10678"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66780.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          147 c          129 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgtgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001043             498 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:13017:11307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001043
VERSION     KCWK01001043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 498)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13017:11307"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..460
                     /note="immunoglobulin light chain variable region"
     V_region        115..460
     V_segment       115..423
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <391..>432
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66781.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       424..460
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        461..>498
                     /gene="IGLC"
BASE COUNT           94 a          169 c          124 g          111 t
ORIGIN      
        1 acatgggggg ggcagcccaa ccctgggtct gtggcctcag aggtagccgt gtccaccatg
       61 gccctgactc ctctcctcct cctgctcctc tctcactgca caggttccct ctcccagcct
      121 gtgctgactc agccaccctc cctgtctgca tccccgggag catcggccag actcccctgc
      181 accctgagca gtgacctcag tgttggtaat aaaaacatgt actggtacca acagaagcca
      241 gggagcgctc ccaggttatt cctatactac tactccgact cagacaagca gctgggacct
      301 ggggtcccca atcgagtctc tggctccaag gagacctcaa ctaacacagc gtttttgctc
      361 atctctgggc tccagcctga ggacgaggcc gattattact gtcaggtgtt tgacagtagt
      421 gctgtgttat tcggaggagg gacccgactg accgtcctag gtcagcccaa ggctgccccc
      481 tcggtcactc tcttcccg
//
LOCUS       KCWK01001044             299 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:12315:12054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001044
VERSION     KCWK01001044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 299)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:12315:12054"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..261
                     /note="immunoglobulin light chain variable region"
     V_region        6..261
     V_segment       6..225
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>233
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66782.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       229..261
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        262..>299
                     /gene="IGLC"
BASE COUNT           66 a           84 c           89 g           60 t
ORIGIN      
        1 acatgggggg agacaacatt ggaattaaaa ctgtgcactg gtaccagcag aagccaccgc
       61 agggccctgt attggtcatc tttgctgata gtaaacggcc ctcggggatc cctgagcgat
      121 tctctggctc caactcaggg aacaccgcca ccctgaccat cagcagggtc gaggccgggg
      181 atgaggctga ctattactgt caggtgtggg acagtagtag taaatggata ttcggcgggg
      241 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001045             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:8980:17924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001045
VERSION     KCWK01001045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8980:17924"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66783.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          147 c          131 g           97 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctttga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaatta aatttgtcca ctggtaccag cagaagccag cgcaggcccc tgtgaaggtc
      241 atctatgctg atgacaaacg gccctcaggg atccctgaga gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattcc
      361 tgtcaggtgt gggacagtga gactgattat tacatcttcg gttctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001046             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:8097:6082
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001046
VERSION     KCWK01001046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8097:6082"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66784.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          161 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt acctgcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaaataaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001047             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:24085:4284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001047
VERSION     KCWK01001047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:24085:4284"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66785.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           93 a          155 c          125 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaac agtgtcgcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatgatga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aggtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agaggttaca tcttcggtga
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01001048             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:4443:17113
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001048
VERSION     KCWK01001048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:4443:17113"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66786.1"
                     /translation="DYYCQVWDSDSKWVF"
     J_segment       386..419
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>460
                     /gene="IGLC"
BASE COUNT           91 a          146 c          135 g           88 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgagc tgactcagcc
      121 accctcagtg tcagcggcct caggacagac ggccaggatc acctgtggcg gggacagcct
      181 tggaacaaaa tatgtgcact ggtaccagca gaagccaacg caggcccctg tggtggtcat
      241 ctatgctgat aataaacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtgata gtaagtgggt cttcggcgga gggacccggc taaccgtccc
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001049             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:7681:11671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001049
VERSION     KCWK01001049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:7681:11671"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66787.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          101 a          137 c          124 g          104 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctggg gcctcctatg aggtgacaca
      121 gtcaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagcaat
      181 actggcaaat aattatgctc agtggttcca gcagaagcca gaccaggccc ctgtgttggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gttgacagca gtgcccatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001050             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:24573:10932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001050
VERSION     KCWK01001050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24573:10932"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..449
                     /note="immunoglobulin light chain variable region"
     V_region        101..449
     V_segment       101..412
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66788.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           89 a          165 c          122 g          111 t
ORIGIN      
        1 acatggggct gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagtagtga
      181 cctcagtgtt ggtagtaaaa acatctactg gtaccagctg aagccaggga gcgcccccag
      241 gtcattcctg tactactact ccgactcaga caagcagctg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt attactgtca ggtctatgac agtagtgcta atgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01001051             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:2981:18414
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001051
VERSION     KCWK01001051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:2981:18414"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66789.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       411..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          158 c          127 g          106 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccaccatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtatcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat cttttataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtcc ggtattcggc
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001052             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:8038:14170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001052
VERSION     KCWK01001052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:8038:14170"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..403
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66790.1"
                     /translation="DYHCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          163 c          114 g          105 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagtcagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacacacac tggtaccaac agaagccagg gagtcccccc cggtatcttc
      241 tgaaatacaa atcagacaca gaccagggcc aggggtctgg agtccccagc cgcttctctg
      301 gatccaaaga tccttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctatcactgt gccattggtc acagcagcgg tccatacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001053             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:14413:8492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001053
VERSION     KCWK01001053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14413:8492"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..441
                     /note="immunoglobulin light chain variable region"
     V_region        111..441
     V_segment       111..402
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66791.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       411..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          156 c          122 g          108 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctct ccttctcact ctgctggttc actgcacagg gtcctgggcc cagtctgtgc
      121 tgacgcagcc gccctcagca tctggggccc ccggacagag ggtcaccatc tcctgcatta
      181 gcagcagctc caacatcggg gcggcttatt atgtatcctg gtaccaacag ttcccaggaa
      241 cagcccccaa actcctcatc tatgaaaata ataagcgacc ctcaggggtt tctgaccgat
      301 tctctggctc caagtctggt ccctcagcct ccctgaccat cactggactc caatctgagg
      361 atgaggctga ttattactgt ttagcatggg ataccagcct gaattggatc ttcggcggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001054             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:16980:22114
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001054
VERSION     KCWK01001054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16980:22114"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66792.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          141 c          137 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcctatgatc tgactcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccagggtc acctgtgggg gagacaacat
      181 cggaggtgaa gttgtgaatg ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat agcgagcggc cctcagggat cccggagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccgga gatgaggctg actattactg
      361 tcaggtgtgg gaccttaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001055             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14574:11100
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001055
VERSION     KCWK01001055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14574:11100"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66793.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          147 c          131 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001056             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:27595:7763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001056
VERSION     KCWK01001056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:27595:7763"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66794.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          164 c          124 g          108 t
ORIGIN      
        1 atgggggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg cgtccccggg agcatcggcc agactcccct gcaccctgac cagtgacctc
      181 agcgttggta gtaaaaacat gtattggtac cagcagaagc cagggagcgc tcccaggtca
      241 ttcctctact actactccga ctcagacaag cagctgggac ctggggtccc caatcgggtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgactatta ctgtcaggtg tatgacagta gtgctaatgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001057             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:13620:13869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001057
VERSION     KCWK01001057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:13620:13869"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66795.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           88 a          158 c          128 g          110 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccggg aagagtgtct ccatctcctg
      181 ttctggaagc agctccaaca tcggaagtca tagtgtctcc tggtaccagc agctcccagg
      241 aacagctccc aaactcctca tctattatag tgatcaacga gcctcaggtg tctctgaccg
      301 attctctggc tctcagtctg gcacgtcagc ctccctggcc atcagtgggc tccagaccga
      361 ggatgaggct gattattact gcgcagcatg ggatgatagc ctgagcggtt acatcttcgg
      421 tgctgggacc cggctcgccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01001058             358 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:20054:20398
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001058
VERSION     KCWK01001058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 358)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 358)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..358
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20054:20398"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..320
                     /note="immunoglobulin light chain variable region"
     V_region        3..320
     V_segment       3..284
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <248..>292
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66796.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       285..320
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        321..>358
                     /gene="IGLC"
BASE COUNT           84 a          104 c          103 g           67 t
ORIGIN      
        1 acatgggctg actcaggcac cctcagtgtc agcggcctca ggacagacgg ccaggatcac
       61 ctgtggcgga gacaacattg gaattaaaaa tgtccactgg taccagcaga agccagcaca
      121 ggcccctgtg gtagtcatct atgctgataa caaacggccc tcagggatcc ctgagcgact
      181 ctctggctcc aactcaggga atattgccac cctgaccatc agcagggtcg aggccgggga
      241 tgaggcagac tattactgtc aggtgtggga cagtagtagt aaatgggtat tcggcggagg
      301 gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001059             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:26249:4180
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001059
VERSION     KCWK01001059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:26249:4180"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66797.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          164 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cacaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001060             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:10106:10451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001060
VERSION     KCWK01001060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:10106:10451"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66798.1"
                     /translation="YYYCSSYAGSHTYIF"
     J_segment       400..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           80 a          163 c          119 g          111 t
ORIGIN      
        1 acatggggtg gggtctcagg aggcagcgct ctcaggacgt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca cagggtcctg ggctcaggct gccctgactc
      121 agcctccctc tgtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggttat aactatgtct cctggttcca gcagcaccca ggcaaagccc
      241 ccaaactcat gatttatgat gtcactcagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaaatc tggctacacg gcctccctga ccgtctctgg gctccaggct gaggatgagg
      361 cttattatta ctgcagctca tatgcaggca gccacactta catcttcggt cctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01001061             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:10385:3741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001061
VERSION     KCWK01001061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10385:3741"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66799.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          157 c          127 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtc cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaggca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctggccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001062             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:15606:7163
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001062
VERSION     KCWK01001062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:15606:7163"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66800.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          150 c          115 g          109 t
ORIGIN      
        1 acatgggggg agccagtgat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001063             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:20159:5528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001063
VERSION     KCWK01001063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20159:5528"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..397
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66801.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           93 a          155 c          118 g          109 t
ORIGIN      
        1 acatggggtg gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccaa gcctatgctg actcagccgg cctccctctc
      121 agcatctcct ggaacatcag ccagtctcac atgcaccttc agcggtggca tcaatgttgt
      181 tggctaccac atacactggt accagcagaa gccagggagt cctccccggt atcttctgag
      241 atacaaatcg gactcagata agggccaggg ctctggagtc cccagccgct tctctggatc
      301 caaagatgct tcagcgaacg cagggatttt acgcatctct ggactccagt ctgaggatga
      361 ggctgactat tactgtgcca ttgggcacag cagcggtgat tacatcttcg gtgctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001064             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14524:14619
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001064
VERSION     KCWK01001064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14524:14619"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66802.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          162 c          108 g          112 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gttgcacctt gagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccaactga agccagggag tcctccccgg taccttctgt
      241 actactactc agactcaagt aaacaccagg cctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 acgctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001065             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:19136:12367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001065
VERSION     KCWK01001065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19136:12367"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66803.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          142 c          132 g           93 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgaat tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa actgtgcact ggtaccaaca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgat agtagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001066             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:28115:13337
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001066
VERSION     KCWK01001066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:28115:13337"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..436
                     /note="immunoglobulin light chain variable region"
     V_region        103..436
     V_segment       103..399
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66804.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       401..436
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           96 a          150 c          117 g          111 t
ORIGIN      
        1 acatggggtc tggagccagg gatcccttcc aatatcagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcaatgactg tgcttccagc
      181 actggagcag tcaccagtgg tcactctcca cactggttcc agcagaaacc tggacaagcc
      241 cccaagacac tgatttataa tacaaactac agacactcct ggactcctgc ccggttctca
      301 ggctccctcc ttgggggtaa agctgccctg acactgtcag gtgcgcagcc tgaggatgag
      361 gctgagtatt attgtttact gtactatagt ggtgctcagc tgttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001067             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:19448:11670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001067
VERSION     KCWK01001067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19448:11670"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66805.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          162 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc cagggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001068             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:3734:11822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001068
VERSION     KCWK01001068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:3734:11822"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66806.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          150 c          121 g          114 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gttcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatgtt gggtattata acgctttgtc ttggtaccaa cagcatccag gcaaagcccc
      241 caaactcatg atttatgacg tcattaagcg gccctcaggg gtttctgatc gcttctctgg
      301 ctccaagtct ggcgacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag aaataatttt ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001069             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:13531:16574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001069
VERSION     KCWK01001069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13531:16574"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66807.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          140 c          136 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcctatgatc tgactcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccagggtc acctgtgggg gagacaacat
      181 cggaggtgaa gttgtgaatt ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat agcgagcggt cctcagggat cccggagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccgga gatgaggctg actattactg
      361 tcaggtgtgg gaccttaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001070             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:9954:3118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001070
VERSION     KCWK01001070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:9954:3118"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66808.1"
                     /translation="DYYCQVWDIYTDHSVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          139 c          137 g          103 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtcaac tggtaccagc agaggccacc gcaggcccct gtggtggtca
      241 tttatgctga ttatgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcggag tcgaggccgg ggatgaggct gactattact
      361 gtcaggtatg ggacatttat actgatcatt cggtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001071             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:20737:17014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001071
VERSION     KCWK01001071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20737:17014"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66809.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          156 c          125 g          107 t
ORIGIN      
        1 acaggggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgataggc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001072             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:26165:14137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001072
VERSION     KCWK01001072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:26165:14137"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66810.1"
                     /translation="DYYCQVWDIYTDHPVIF"
     J_segment       396..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          142 c          135 g          100 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagc ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ctgatcatcc ggtgatattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001073             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:13114:11888
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001073
VERSION     KCWK01001073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13114:11888"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..284
                     /note="immunoglobulin light chain variable region"
     V_region        8..284
     V_segment       8..244
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <212..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66811.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       247..284
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>322
                     /gene="IGLC"
BASE COUNT           68 a           94 c           85 g           75 t
ORIGIN      
        1 acatgggagc ggtggcatca atgttgctgg ctaccacata cactggtatc agcagaagcc
       61 agggagtccc ccccggtatc ttctgaggta caaatcagac tcagataagg gcctgggctc
      121 tggagtcccc agccgcttct ctggatccaa agatgcttca gcgaatacag ggattttaca
      181 catctctggt ttccagtctg aggatgaggc tgactattac tgtgccattg gccacggcag
      241 cggtgattac atcttcggta ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc
      301 ccccacggtc actctgttcc cg
//
LOCUS       KCWK01001074             406 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:23081:13424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001074
VERSION     KCWK01001074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 406)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:23081:13424"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    177..368
                     /note="immunoglobulin light chain variable region"
     V_region        177..368
     V_segment       177..331
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <299..>340
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66812.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       335..368
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        369..>406
                     /gene="IGLC"
BASE COUNT           72 a          134 c          103 g           97 t
ORIGIN      
        1 acatgggggc tcattcctgg ctgtggctca ggaagcagag cctggagcat ctccaccatg
       61 gcctgggctc cactcctcct caccctcctc gctcactgca cagggtcttg ggctgaggtt
      121 gtgttcactc agccccattc tgtgtcgggg tctccggggc agacggtcac catctcctgt
      181 gatttacaaa gataaccaaa gaccctctgg ggtccctgat cggttctctg gctccatcga
      241 cagctcctcc aactctgcct ccctcaccat ctctggactg aaatctgagg acgaggctga
      301 ctattactgt cagtcttatg acagcagcag tgtattattc ggaggaggga cccggctgac
      361 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001075             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:23366:8667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001075
VERSION     KCWK01001075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:23366:8667"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66813.1"
                     /translation="DYHCQVFDSRDVLF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          159 c          124 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcatcct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccaga
      241 ttattcctgt actactattc cgactcagac aaggagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggaaac ctcaagtaac acagcgtttt tgctcatctc tggactccag
      361 cctgaggacg aggccgatta tcactgtcag gtgtttgaca gtcgtgatgt gttgttcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001076             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:16404:17294
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001076
VERSION     KCWK01001076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16404:17294"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..435
                     /note="immunoglobulin light chain variable region"
     V_region        104..435
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66814.1"
                     /translation="EYYCCSHAGSDIFVLF"
     J_segment       401..435
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           85 a          158 c          125 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggcggttata actatgtctc ctggtaccaa cagcatccag acacagcccc
      241 caaactcatg atttatgagg tcactaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgaatattac tgctgctcac atgcaggcag tgatattttc gtgttattcg gaggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001077             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:18286:13399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001077
VERSION     KCWK01001077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18286:13399"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..287
                     /note="immunoglobulin light chain variable region"
     V_region        7..287
     V_segment       7..252
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66815.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       257..287
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>325
                     /gene="IGLC"
BASE COUNT           69 a           96 c           82 g           78 t
ORIGIN      
        1 acatggggtc accatctcct gcactggaac cagcagtgat attgggtatt atcatgctgt
       61 gtcttggtac cagcatcatc caggcaaagc ccccaaactc atgatttatg aggtcaataa
      121 acggcccgca ggggtctctg atcgcttctc tggctccaag tctggcaaca cggcctccct
      181 gaccatctct gggctccaga ctgaggatga ggctgattat tactgcagct catatggagg
      241 cagcaatagt ttattcttcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc
      301 tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001078             276 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:28956:11795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001078
VERSION     KCWK01001078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 276)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 276)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..276
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:28956:11795"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..238
                     /note="immunoglobulin light chain variable region"
     V_region        8..238
     V_segment       8..201
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <169..>210
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66816.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       202..238
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        239..>276
                     /gene="IGLC"
BASE COUNT           57 a           82 c           81 g           56 t
ORIGIN      
        1 acatgggggc atcagcagca gcaagggaag gccccccggt acttgatgtg gcttaaaagt
       61 gaaggcagcc atagcaaggg ggacgggatc cctgatcgct tctcaggctc cagctccggg
      121 gctgagcgct acctcaccat ctccaacctc cagtctgagg atgaggctga ttattactgt
      181 cagacctggg atactgacat tgtgttattc ggaggaggga cccggctgac cgtcctaggt
      241 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001079             282 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:7044:14767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001079
VERSION     KCWK01001079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 282)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7044:14767"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..244
                     /note="immunoglobulin light chain variable region"
     V_region        10..244
     V_segment       10..207
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <169..>216
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66817.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       210..244
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        245..>282
                     /gene="IGLC"
BASE COUNT           56 a           81 c           84 g           61 t
ORIGIN      
        1 acatgggata gtgtgcattg gtaccagcag aagccaccgc gggcccctgt attggtcatc
       61 tctgttgata gcgaacggcc ctcagggatc cctgagcgat tctctggttc cagatcaggg
      121 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      181 caggtgtggg ataatattta taaatacgcg gtattcggcg gagggacccg gctgaccgtc
      241 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001080             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:18964:12662
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001080
VERSION     KCWK01001080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18964:12662"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66818.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          148 c          129 g           96 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gtactggtca
      241 tcttttacta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001081             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:6929:2913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001081
VERSION     KCWK01001081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6929:2913"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66819.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtatcagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001082             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:18815:2427
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001082
VERSION     KCWK01001082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18815:2427"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66820.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          164 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gcctcagaca accagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001083             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:13728:12036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001083
VERSION     KCWK01001083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13728:12036"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66821.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          163 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg acctgaggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001084             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:12361:19242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001084
VERSION     KCWK01001084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12361:19242"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66822.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       405..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           90 a          160 c          119 g          108 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgacccagcc aacctccctc
      121 tcagcatctc cgggagcatc atccagactc aactgcacct tgagcagtgg cgtcaatgtg
      181 ggtagttaca gcatattctg gtaccagcag aagccaggga gtcctccccg gtaccttctg
      241 tactaccagt cagactcaag gaagcaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcagccaa tgcagggctg ttactgatct ctgggctcca gtctgaagat
      361 gaggctgact attactgtgc cctatggcac agcagcgctt cttgcatctt cggtggtggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01001085             346 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:23904:6433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001085
VERSION     KCWK01001085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 346)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 346)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:23904:6433"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..308
                     /note="immunoglobulin light chain variable region"
     V_region        8..308
     V_segment       8..271
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <233..>280
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66823.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       272..308
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        309..>346
                     /gene="IGLC"
BASE COUNT           74 a           97 c          104 g           71 t
ORIGIN      
        1 acatgggtcg gtgtcagtgt ccccgggaca gacggccagg atcacctgtg ggggagacaa
       61 tattggaagt aaaaatgtgc actggtacca gcaggagcca ccgcaggccc ctgtgttggt
      121 catcttttat gataacaaac ggccctcagg gatccctgag cgattctctg gctccaaatc
      181 agggaacatc gccaccctga ccatcagcga ggccgaggcc ggggatgagg ctgactatta
      241 ctgtcagctg tgggacagta gtgttgatca tggcttattc ggaggaggga cccggctgac
      301 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001086             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:9857:10151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001086
VERSION     KCWK01001086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:9857:10151"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..436
                     /note="immunoglobulin light chain variable region"
     V_region        90..436
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66824.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           91 a          161 c          111 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt tagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc ggtagtggga
      421 cccggctcac cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001087             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:19438:17858
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001087
VERSION     KCWK01001087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19438:17858"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66825.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       405..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           89 a          160 c          121 g          107 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgacccagcc aacctccctc
      121 tcagcatctc cgggagcatc agccagactc agctgcacct tgagcagtgg cgtcaatgtg
      181 ggtagttaca gcatattctg gtaccagcag aagccaggga gtcctccccg gtaccttctg
      241 tactaccagt cagactcaag gaagcaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcagccaa tgcagggctg ttactgatct ctgggctcca gtctgaagat
      361 gaggctgact attactgtgc cctatggcac agcagcgctt cttgcatctt cggtggtggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01001088             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:6662:11936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001088
VERSION     KCWK01001088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6662:11936"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66826.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          148 c          131 g           96 t
ORIGIN      
        1 acatgggggg gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001089             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18572:13716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001089
VERSION     KCWK01001089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18572:13716"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66827.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          148 c          129 g           98 t
ORIGIN      
        1 acatgggctg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctccgatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa gagtgtgcac tggtaccaac acaagccacc gcaggcccct atcctggtca
      241 tctattatta taccgaacgg ccctcggcga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacactact attgatcatg gctttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001090             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:23565:13889
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001090
VERSION     KCWK01001090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23565:13889"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..396
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66828.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           95 a          156 c          116 g          107 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcatctcctg gaacatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 ggctaccaca tacactggta ccagcagaag ccagggagtc ctccccgata tcttctgaga
      241 tacaaatcgg actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagcgaacac agggatttta cgcatctctg ggctccagtc tgaggatgag
      361 gctgactatt actgtgccat tggacacagc agcggtgatt acatcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001091             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:21720:8725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001091
VERSION     KCWK01001091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21720:8725"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66829.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          156 c          119 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catacactgg taccagcaga agtcagggag tcctccccgg tatcttctaa
      241 gatacaaatc agactcagat cagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acggggattt tacacgtctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtga ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001092             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:26305:13680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001092
VERSION     KCWK01001092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:26305:13680"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66830.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          155 c          118 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcttccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cgacggtggc atcaatgttg
      181 ctggctacca catacactgg taccaacaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt caccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtga ttacatcttc ggtgctggga
      421 cccgactcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001093             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:12494:11313
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001093
VERSION     KCWK01001093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12494:11313"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66831.1"
                     /translation="DYYCQVYDSNAVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          165 c          119 g          108 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtact gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gcagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctct actactactc cgactcagac aaccaactgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgccag gtgtatgaca gtaatgctgt tttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001094             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15993:10465
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001094
VERSION     KCWK01001094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15993:10465"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66832.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          140 c          140 g           97 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactttac aggctctgcg gcctcctatg aggtgactca
      121 gccacgctca gtgtccgtgt cccccggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt aaaagtgtgc agtggtacca gcagacgcca ccgcaggccc ctgtactggt
      241 catttatggt gatagggaac ggccctcagg gatccctgag cgattctctg gctccaactc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggatagta gtagtaaata tgtattattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001095             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:22370:10212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001095
VERSION     KCWK01001095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:22370:10212"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66833.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          147 c          130 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc cct
//
LOCUS       KCWK01001096             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:20191:8347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001096
VERSION     KCWK01001096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20191:8347"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66834.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          140 c          140 g           96 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgc ggcctcctat gaggtgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taaaagtgtg cagtggtacc agcagacgcc accgcaggcc cctgtactgg
      241 tcatttatgg tgatagggaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggatagc agtagtaaat atgtattatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001097             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:8820:21391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001097
VERSION     KCWK01001097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8820:21391"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66835.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          153 c          122 g          112 t
ORIGIN      
        1 acatgggggc ttggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgcc ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatggagg cagcaatagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001098             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:9493:2338
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001098
VERSION     KCWK01001098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:9493:2338"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66836.1"
                     /translation="DYYCCSYAGSDTFVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          160 c          123 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa caacatccag ccacagcccc
      241 caaactcgtg atttatgagg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggc ctccagcctg aggacgaggc
      361 tgattattac tgctgctcat atgcaggtag cgacactttc gtgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001099             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:20228:11904
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001099
VERSION     KCWK01001099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:20228:11904"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..422
                     /note="immunoglobulin light chain variable region"
     V_region        105..422
     V_segment       105..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66837.1"
                     /translation="DYYCYSSDSNSKWLF"
     J_segment       394..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>464
                     /gene="IGLC"
BASE COUNT           99 a          142 c          124 g           99 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccata gcctggattc
       61 ctctcctact ccccatcctc actttctgca caggctctgc agcctcctat gagatgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaaa aaaatatact tattggttcc cgcagaaggc aggccagccc cctatggtga
      241 tcatctatga ggacaccaaa cggccctctg ggatccctga gagattctct ggctccagct
      301 cagggacagt ggccaccttg actctcagtg gggcccaggt ggaggatgaa ggtgactact
      361 actgttactc atcagacagc aatagtaaat ggctattcga cggagggacc cggctgaccg
      421 tcgtaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001100             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:15026:10936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001100
VERSION     KCWK01001100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15026:10936"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66838.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tattggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001101             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:13318:12282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001101
VERSION     KCWK01001101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13318:12282"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..409
                     /note="immunoglobulin light chain variable region"
     V_region        79..409
     V_segment       79..372
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <328..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66839.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       373..409
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           87 a          143 c          126 g           91 t
ORIGIN      
        1 acatgggggg acatgtcagc catggcctgg acgcctctcc tcctcagcct cctcgctcac
       61 tgcacaggct ctgtggcctc ctatgagctg actcagccac cctcagtgtc ggtgtcccca
      121 ggacagacag ccagcatcac ctgctctgga aataaattgg ggaatgtata tgcttactgg
      181 ttccagcaga agccaggcca ggcccctgta gtggtcatct acaaagatac caaccggccc
      241 tcagggatcc ctgagcgatt ctctggctcc gactcaggga acacggccac cctgaccatc
      301 agcagggtcg aggctgggga tgaggccgac tatttttgtg ctgcagccta tggcagtggc
      361 agcagctggc agtgggtatt cggcggaggg acccggctaa tcgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001102             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:14104:12429
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001102
VERSION     KCWK01001102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14104:12429"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66840.1"
                     /translation="DYYCCSRSSSSTYVF"
     J_segment       399..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           82 a          162 c          117 g          111 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacgtt ggtggttata actctgtctc ctggtaccaa caacacccag gcaaagcccc
      241 caaagtcatg atttttggtg tcaataatcg gccctctggg gtctctgacc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagcctg aggacgaggc
      361 tgactattac tgttgttcac gttcaagcag tagcacttac gtcttcggtc ctgggacccg
      421 gctcaccgtc ctgggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01001103             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:7375:13820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001103
VERSION     KCWK01001103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7375:13820"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66841.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          157 c          127 g          111 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagtc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001104             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:19438:14366
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001104
VERSION     KCWK01001104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19438:14366"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..448
                     /note="immunoglobulin light chain variable region"
     V_region        115..448
     V_segment       115..411
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66842.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       412..448
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           87 a          164 c          131 g          104 t
ORIGIN      
        1 acatggggca gtgtggctgc ctcagcagag ccctgaggag tctgcaccat ggcctggacc
       61 ccaatcctcc tcctcctcct cactctcctc cttcactgca cagggtctct ctcccagcct
      121 gtgctgactc agtcgccctc tgcctctgcc tccctgggag cctcggtcaa gctcacctgc
      181 actctgagca gtggacacag gagctacacc atcgcgtggc atcagcagca gcaagggaag
      241 gcccctcgat acttgatgtg gcttaaaagt gatggcagcc acagcaaggg ggacgggatc
      301 cctgatcgct tctcaggctc cagctccggg gctgagcgct acctcaccat ctccaacctc
      361 cagtctgagg atgaggctga ttattattgt cagacgtggg atattggcat ttgggtgttc
      421 ggcggaggga cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01001105             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:5253:8938
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001105
VERSION     KCWK01001105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5253:8938"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66843.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       404..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           87 a          157 c          126 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggcggtt ataactatgt ctcctggtac caacaacatc cagacacagc
      241 ccccaaactc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgctgct cacatgcagg cagtgatatt ttcgtgttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01001106             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:20142:12744
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001106
VERSION     KCWK01001106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20142:12744"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..401
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66844.1"
                     /translation="DYYCQSYDSLSAVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           87 a          158 c          131 g          109 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc cgggcccagt
      121 ctgtactgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatttcct
      181 gcactgggag cagctccaac atcggggcgg gttattatgt gcagtggtac cagcagcttc
      241 caggaacggc ccccaaactc ctcatctatg aaaatgataa gcgaccctca ggggtttctg
      301 atcgattctc tggctccaag tctggtacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cctgagcgct gtgttattcg
      421 ggggagggac ccggctgacc gtcctaggtc agcccaagtc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001107             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:19759:9690
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001107
VERSION     KCWK01001107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19759:9690"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66845.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       414..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          157 c          122 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccggaca gagggtcacc atctcctgca
      181 ttagcagcag ctccaacatc ggggcggctt attatgtatc ctggtaccaa caattcccag
      241 gaacagcccc caaactcctc atctttgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtccctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattac tgtttagcat gggataccag cctgaattgg atcttcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001108             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:7881:6689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001108
VERSION     KCWK01001108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:7881:6689"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66846.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          153 c          121 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggccc aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001109             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:15557:6060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001109
VERSION     KCWK01001109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15557:6060"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66847.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          153 c          114 g          116 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttggtaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcacc agggctctgg agtccccagc cgcttctctg
      301 ggtccaagga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattattgt atgatttggc acaacaatgc ttattgggta ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001110             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:21262:4138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001110
VERSION     KCWK01001110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21262:4138"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66848.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          160 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctttgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagag gccagggagc gctcccaggt
      241 tattcctgta ttactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaggtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001111             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:9136:15096
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001111
VERSION     KCWK01001111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9136:15096"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..216
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66849.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       221..251
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           61 a           88 c           72 g           68 t
ORIGIN      
        1 acatgggggg tattatcatg ctgtgtcttg gtaccaacat catccaggca aagcccccaa
       61 actcatgatt tatgaggtca ataaacggcc cgcaggggtc tctgatcgct tctctggctc
      121 caagtctggc aacacggcct ccctgaccat ctctgggctc cagactgagg atgaggctga
      181 ttattactgc agctcatatg caggcagcaa cactttattc ttcggaggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001112             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:14769:20418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001112
VERSION     KCWK01001112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14769:20418"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66850.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       384..419
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>458
                     /gene="IGLC"
BASE COUNT           94 a          143 c          123 g           98 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaagatcac ctgctctgga gatgcactgc
      181 caaaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtg ttgatcatcg
      241 atgaggacac caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcagcaga cagcagtggt tatggcttat tcggaggagg gacccggctg accgtcctac
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001113             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:9975:13210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001113
VERSION     KCWK01001113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:9975:13210"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66851.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          162 c          108 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaaga cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001114             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:10056:10448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001114
VERSION     KCWK01001114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10056:10448"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66852.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          162 c          124 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcggccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001115             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:25804:11599
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001115
VERSION     KCWK01001115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:25804:11599"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..421
                     /note="immunoglobulin light chain variable region"
     V_region        91..421
     V_segment       91..386
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66853.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       391..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           86 a          152 c          114 g          107 t
ORIGIN      
        1 acatgggggc agcgctctca ggacttctcc accatggtct gggctctgct cctcctcacc
       61 ctcctcactc agggcacagg atcctgggct caggctgccc cgactcagac tccctctgtg
      121 tccgggtctc ctggacagtc ggtcaccatc tcctgcactg gaaccagcag tgatattggg
      181 tattatcatg ctgtgtcttg gtaccagcat catccaggca aagcccccaa actcatgatt
      241 tatgaggtca ataaacggcc cgcaggggtc tctgatcgct tctctggctc caagtctggc
      301 aacacggcct ccctgaccat ctctgggctc cagactgagg atgaggctga ttattactgc
      361 agctcatatg caggcagcaa cactttattc ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001116             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:26351:16960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001116
VERSION     KCWK01001116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:26351:16960"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..254
                     /note="immunoglobulin light chain variable region"
     V_region        9..254
     V_segment       9..217
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66854.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       220..254
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           58 a           86 c           88 g           60 t
ORIGIN      
        1 acatgggatt ggaagtaact atgtgcactg gtaccagcag aagccagggc aggcccctgt
       61 agagatcatc tttgctgata acaaacggcc ctcagggatc cctgagcgat tctctggctc
      121 caactcaggg atcaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga
      181 ctatttctgt caggtgtggg gcagtcgtag tgatcatccg gtattcggcg gagggacccg
      241 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001117             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11166:10775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001117
VERSION     KCWK01001117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11166:10775"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66855.1"
                     /translation="DYYCQSTDTSGNYIF"
     J_segment       386..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT          105 a          131 c          123 g          101 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctggggcc tcctttgagc tgacacaggc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gaggaatact
      181 ggcaaaaaaa tatgctcagt ggttgcagca gaagccaggc caggcccctg tgttggtaat
      241 atataaagac agtgagaggc cctcagggat ccctgaacga ttctctagtt ccagttcagg
      301 gacaacagtt gccttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcaaca gacaccagtg gtaattacat cttcggtgct gggacccggc tcaacgtcct
      421 aggtcagccc aaggcttccc ccacggacac tctgttcccg
//
LOCUS       KCWK01001118             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:4617:19815
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001118
VERSION     KCWK01001118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4617:19815"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66856.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          161 c          126 g          109 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga ggccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaggtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001119             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:13561:19334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001119
VERSION     KCWK01001119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13561:19334"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66857.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       407..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          153 c          130 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaacatc ggggcgggtt tttatgtatc ctggtaccag cagttcccag
      241 gaaaagcccc caagctcctc atctttgaaa ataacaagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattat tgttcatcat gggaaagcag cctgaattgg gtattcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001120             517 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:4982:4791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001120
VERSION     KCWK01001120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 517)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:4982:4791"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    149..479
                     /note="immunoglobulin light chain variable region"
     V_region        149..479
     V_segment       149..442
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <404..>451
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66858.1"
                     /translation="DYYCAAWDESLRGYIF"
     J_segment       443..479
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        480..>517
                     /gene="IGLC"
BASE COUNT          104 a          157 c          142 g          114 t
ORIGIN      
        1 acatggggag agtatgaaga gagggagaga tttgggtgaa gcgcagcttc agctgtgggt
       61 acagaaggca ggactcagga caatctccag catggcctgg ttccctctcg tcctcaccct
      121 cctcactcac tgtgcagggt cctgggccca gtctgcgctg actcagcctc cctcagcgtc
      181 tgcggccgcc aggaacagtg tcgccatctc ctgttctgga ggcagttcca acatcggaag
      241 tcatagtgta tcctggtatc agcagctccc aggaacagct cccaaactcc tcatctatta
      301 tgatgatcaa cgagcctcag gtgtctctga ccgattctct ggctccaggt ctggcacgtc
      361 agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt actgcgcagc
      421 atgggatgag agcctgagag gttacatctt cggtaatggg acccggctca ccgtcctagg
      481 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01001121             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:19772:7991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001121
VERSION     KCWK01001121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19772:7991"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..401
                     /note="immunoglobulin light chain variable region"
     V_region        101..401
     V_segment       101..364
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <329..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66859.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       365..401
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>439
                     /gene="IGLC"
BASE COUNT           85 a          136 c          119 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggca ccttgactat
      301 cagtggggcc caggtggagg atgaagctga ctactactgt tactcagcag acagtagtgg
      361 tcatggcttc ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc
      421 ctcggtcact ctcttcccg
//
LOCUS       KCWK01001122             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10911:14905
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001122
VERSION     KCWK01001122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10911:14905"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66860.1"
                     /translation="DYYCAMWHSSASYFF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          161 c          112 g          112 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctgt
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgcttc ttacttcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001123             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:11580:13638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001123
VERSION     KCWK01001123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11580:13638"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66861.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          147 c          131 g           96 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gttctggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg aatctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaagt cttgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001124             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:24804:12383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001124
VERSION     KCWK01001124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24804:12383"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66862.1"
                     /translation="DYYCQVYDSSSNVLF"
     J_segment       414..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          163 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tatatgacag tagttctaac gtattattcg
      421 gaagagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001125             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:15561:13246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001125
VERSION     KCWK01001125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15561:13246"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..455
                     /note="immunoglobulin light chain variable region"
     V_region        110..455
     V_segment       110..418
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66863.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       419..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           94 a          168 c          120 g          111 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      181 gagcagtgac ctcagtgttg gtaataaaaa catgtactgg taccaacaga agccagggag
      241 cgctcccagg ttattcctat actactactc cgactcagac aagcagctgg gacctggggt
      301 ccccaatcga gtctctggct ccaaggagac ctcaactaac acagcgtttt tgctcatctc
      361 tgggctccag cctgaggacg aggccgatta ttactgtcag gtgtttgaca gtagtgctgt
      421 gttattcgga ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01001126             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:6101:9932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001126
VERSION     KCWK01001126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6101:9932"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66864.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       414..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          164 c          124 g          107 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcactgac
      181 ctcagtgttg gtggtaaaaa catgtactgg taccagcaga agccaggaag cgctcccagg
      241 ttattgctgt attaccactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgccaa cacgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01001127             383 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:20387:9396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001127
VERSION     KCWK01001127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 383)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 383)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20387:9396"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    51..345
                     /note="immunoglobulin light chain variable region"
     V_region        51..345
     V_segment       51..308
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <276..>317
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66865.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       311..345
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        346..>383
                     /gene="IGLC"
BASE COUNT           72 a          122 c          104 g           85 t
ORIGIN      
        1 acatgggggg ctcattcctg gctgtggctc aggaagcaga gcctggagca tctccggggc
       61 agacggtcac catctcctgc acccgcagca gtggcagcat tggcaacagc tatgtgtact
      121 ggttccagca gcggccgggc agcgtcccca ctattgtgat ttacaaagat gaccaaagac
      181 cctctggggt ccctgatcga ttctctggct ccatcgacag ctcctccaac tctgcctccc
      241 tcaccatctc tggactgaag tctggggacg aggctgacta ttactgtcag tcttttgaca
      301 gcagcagtgt cttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg
      361 ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001128             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:16823:17318
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001128
VERSION     KCWK01001128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16823:17318"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..416
                     /note="immunoglobulin light chain variable region"
     V_region        90..416
     V_segment       90..378
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66866.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       380..416
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           93 a          148 c          110 g          103 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tgtgctgact cagcctccct cagcgtctga
      121 ggccgccagg aagagtgtca ccatctcctg ttctggaagc acctccaaca tcggaagcaa
      181 taatgtatcc tggtaccagc agctcccagg aacagctccc aaactcctct tttattataa
      241 tgatcaacga gcctcaggtg tctctgaccg attctcttgc tccaagtctg gcacgtcagc
      301 ctccctggcc atcagtgggc tccagaccga ggatgaggct gattattact gcgcagcatg
      361 ggatgataac ctgagcggct acatcttcgg tgctgggacc cggctcaccg tcctaggtca
      421 gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001129             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:26782:10374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001129
VERSION     KCWK01001129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:26782:10374"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    50..374
                     /note="immunoglobulin light chain variable region"
     V_region        50..374
     V_segment       50..335
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <299..>346
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66867.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       342..374
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        375..>412
                     /gene="IGLC"
BASE COUNT           81 a          126 c          128 g           77 t
ORIGIN      
        1 acatgggggg aagaaaatcc catgggctga ggcggtggac tctgcggcct cccatgatct
       61 gactcagcca ccctcggtga ccgtgtcccc aggacagacg gccaggatca cctgcggggg
      121 agacaagatt cgaagtgaag ttgtgaactg gtaccagcag aagccagcgc aggcccctgt
      181 attggtcatc tttgctgata ccgaacggcc cgcagggatc cccgagcgat tctctggctc
      241 caaatcaggg aacacggcca ccctgaccat ccgcggggtc gaggccgggg atgaggctga
      301 cttttactgt caggtgtggg acattcgtag tgatcgtccg ctattcggcg gagggacccg
      361 gctcaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001130             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:19734:12361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001130
VERSION     KCWK01001130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19734:12361"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66868.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       402..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           89 a          155 c          121 g          112 t
ORIGIN      
        1 acatgggggg tggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc aagcctatgc tgactcagcc ggcctccctc
      121 tcagcatctc ctggagcatc agccagtctc acatgcacct tcagcggtgg catcaatgtt
      181 gctgtctacc acgtacactg gtaccagcag aagccaggga gtcccccccg gtatcttctg
      241 aggtacaaat cagactcaga taagggccag ggttctgggg tccccagccg cttctctgga
      301 tccagtaata cttcagcgaa cacagggatt ttacgcgttt ctgggatcca gtctgaggat
      361 gaggctgact attactgtgc cattgggcac agcagcggtc tttacatctt cggtgctggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01001131             497 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:25880:6774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001131
VERSION     KCWK01001131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 497)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 497)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..497
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:25880:6774"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    129..459
                     /note="immunoglobulin light chain variable region"
     V_region        129..459
     V_segment       129..422
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>431
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66869.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       423..459
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        460..>497
                     /gene="IGLC"
BASE COUNT           97 a          159 c          127 g          114 t
ORIGIN      
        1 acatggggga tttgggtgaa gcgcagcctc agctgtgggt acagaaggca ggactcagga
       61 caatctccag catggcctgg ttccctctcc tcctcaccct cctcactcac tgtgcagggt
      121 cctgggccca gtctgtgttg actcagcctc cctcagcgtc tgaggccgcc gggaagagtg
      181 tcaccatctc ctgttctgga agcagctcca acatcggaag taatagtgta tcctggtacc
      241 aacaactccc agaaacggct cccaaactcc tcatgtatta taatcatcgg cgagcctcag
      301 gtgtctctga ccgattctct ggctccaagt ctggcccttc agcctccctg gccatcagtg
      361 ggctccagac cgaggatgag gctgattatt actgcgcagt atgggatgat agcctgaccg
      421 gttacatctt cggtactggg acccggctca ccgtcctagg tcagcccaag gcttccccca
      481 cggtcactct gttcccg
//
LOCUS       KCWK01001132             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:16656:8203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001132
VERSION     KCWK01001132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16656:8203"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66870.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           85 a          143 c          142 g           93 t
ORIGIN      
        1 atggggctgg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tggaagtgaa gttgtgaact ggtaccagcg gaagccagcg caggcccctg tgctggtcat
      241 ctatgctgat agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg ggtgaggctg actattactg
      361 tcaggtgtgg gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001133             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:13519:19621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001133
VERSION     KCWK01001133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13519:19621"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66871.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          153 c          120 g          110 t
ORIGIN      
        1 acatggcggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001134             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:13236:7423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001134
VERSION     KCWK01001134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13236:7423"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..398
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66872.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       400..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           95 a          153 c          111 g          116 t
ORIGIN      
        1 acatggggga gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctcgca gcctgtgctg actcagccaa cctccctctc
      121 agcttctcct ggagcatcag ccagactcac ctgcaccttg aacagtggca tcagtgttgc
      181 taattacagg atattctggt accaccagaa gccagggagt cctccccggt atcttctgaa
      241 ctaccacaca gactcagata ttcaccaggg ctctggagtc cccagccgct tctctggatc
      301 caaagatgct tcggccaatg cagggatttt actcatctct ggactccagt ctgaggatga
      361 ggctgactat tactgtatga tttggcacaa caatgcttat tgggttttcg gcggagggac
      421 ccggctaacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001135             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:25991:5095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001135
VERSION     KCWK01001135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25991:5095"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66873.1"
                     /translation="DYYCAAWDDTLSGPVF"
     J_segment       411..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          158 c          128 g          106 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtatcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat cttttataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataccc tgagcggtcc ggtattcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001136             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:6424:11467
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001136
VERSION     KCWK01001136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:6424:11467"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..433
                     /note="immunoglobulin light chain variable region"
     V_region        88..433
     V_segment       88..396
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66874.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           91 a          161 c          108 g          111 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gaacatcagc cagactcagc tgcaccttga gcagtggcaa tgttggcagt
      181 tacagcatat tctggtacca gcagaagcca gggagtcctc cccggttcct tctttactac
      241 tactcagact caagtaacca ccaggactct ggagtcccca gccgcttctc tggatcgaaa
      301 gatgcttcag ccaatgcagg gcttttactg atctctgggc tccagtctga tgatgaggct
      361 gactattact gtgccacatg gcacagcagc gcttcttaca tcttcggtcc tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01001137             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:15064:11967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001137
VERSION     KCWK01001137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15064:11967"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66875.1"
                     /translation="DYYCQVWDITGDHHVLF"
     J_segment       391..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          142 c          138 g          100 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagt ctctgcggcc tcttatgatc tgactcagcc
      121 accctcggtg tcagtgcccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tgaaaatgga gttgtgagct ggtaccagca gaagccaccg caggcccctc tactggtcat
      241 ctatgctgat agcgcgcggc ccttagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgaccg tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattactg gtgatcatca tgtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001138             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12114:12841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001138
VERSION     KCWK01001138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12114:12841"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..402
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66876.1"
                     /translation="DYSCCSYRSGNTWLF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           81 a          157 c          129 g          109 t
ORIGIN      
        1 acatgggggg ctggggtctc aggaggcagc gctctcggga cgtctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag tctgtcctga
      121 ctcagcctcc ctcagtgtcc aagtctcttg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga cattggtggt tatgatggcg tctcctggta ccagcagcac tcagggacag
      241 cccccagact cctgatttat gatgtcacta agcggccctc aggggtctcg gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tcaccatctc tgggctccag actgaggacg
      361 aggctgatta ttcttgttgc tcatatagga gtggaaacac ttggctattc ggcggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001139             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:25336:8795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001139
VERSION     KCWK01001139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:25336:8795"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66877.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       217..251
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           57 a           87 c           86 g           59 t
ORIGIN      
        1 acatggggga actaaatatg tgcactggta ccagcagaag ccagcgcagg cccctgtgtt
       61 ggtcatctat gctgatacca gacggccctc agggatccct gagcgattct ctggctccaa
      121 ctcagggaac accgccaccc tgaccatcag cggggtcgag gccgggtatg aggctgacta
      181 tttctgtcag gtgtgggacg atagtagtga tcatccggta ttcggcggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001140             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:22346:13455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001140
VERSION     KCWK01001140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:22346:13455"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..279
                     /note="immunoglobulin light chain variable region"
     V_region        8..279
     V_segment       8..235
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66878.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       249..279
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>317
                     /gene="IGLC"
BASE COUNT           65 a           98 c           79 g           75 t
ORIGIN      
        1 acatgggctc ctgcactgga accagcagtg atgttgggta ttatcatgct gtgtcttggt
       61 accagcatca tccaggcaaa gcccccaaac tcatgattta tgaggtcaat aaacggcccg
      121 caggggtctc tgatcgcttc tctggctcca agtctggcaa cacggcctcc ctgaccatct
      181 ctgggctcca gactgaggat gaggctgatt attactgcag ctcatatgca ggcagcaacg
      241 ctttattctt cggacgaggg acccgcctga ccgtcctagg tcagcccaag gctgccccct
      301 cggtcactct cttcccg
//
LOCUS       KCWK01001141             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10177:20911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001141
VERSION     KCWK01001141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10177:20911"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66879.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       413..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           92 a          151 c          129 g          116 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcagtattt
      181 cttgcactgg gagcagctcc aacattggag gttattatgt gcagtggtac cagcagcttc
      241 caggaacggc ccccaaactc ctcatctatg aaaatgataa acgaccctca gggatttctg
      301 atcgattctc tggctcccag tctgattcct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagcttgagt gttgtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01001142             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:20663:18314
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001142
VERSION     KCWK01001142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20663:18314"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66880.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       391..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          138 c          139 g           98 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagg
      121 caccctcgat ttcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtgaac tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tgtatgctga tagcgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacatgaat agtcatcatc tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001143             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:16837:13499
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001143
VERSION     KCWK01001143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16837:13499"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66881.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           98 a          152 c          112 g          117 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttggtaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcatc aggggtctgg agtccccagc cacttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001144             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:9097:12789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001144
VERSION     KCWK01001144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:9097:12789"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..417
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66882.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       418..454
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           94 a          157 c          130 g          111 t
ORIGIN      
        1 acatgggggg gtgaagcgca gcttcagctg tgggtacaga aggcaggact caggacaatc
       61 tccagcatgg cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg
      121 gcccagtctg tgctgactca gcctccctca gtgtctgagg ccgccaggaa cagtgtcgcc
      181 atctcctgtt ctggaagcag ctccaacatc ggaagtcata gtgtatcctg gtaccagcag
      241 ctcccaggaa cagctcccca actcctcatc tattatgatg atcaacgagc ctcaagtgtc
      301 tctgaccgat tctctggctc caggtctggc acgtcagcct ccctggccat cagtgggctc
      361 cagaccgagg atgaggctga ttattactgc gcagcttggg atgatagcct gagaggttac
      421 atcttcggtg atgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCWK01001145             510 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:21848:17660
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001145
VERSION     KCWK01001145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 510)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:21848:17660"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    142..472
                     /note="immunoglobulin light chain variable region"
     V_region        142..472
     V_segment       142..435
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <397..>444
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66883.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       436..472
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        473..>510
                     /gene="IGLC"
BASE COUNT          105 a          158 c          134 g          113 t
ORIGIN      
        1 acatggggga agagagggag agatttgggt gaagcgcagc ttcagctgtg ggtacagaag
       61 gcaggactca ggacaatctc cagcatggcc tggttccctc tcgtcctcac cctcctcact
      121 cactgtgcag ggtcctgggc ccagtctgtg ctgactcagc ctccctcaac gtctgaggcc
      181 gccaggaaga gtgtcaccat ctcctgttct ggaagcaact ccaacatcgg aagttataat
      241 gtgtcctggt accagcagct cccaggaaca gctcccaaac tcctcatcta ttataatgat
      301 caacgagcct caggtgtctc tgaccgattc tctggctcca agtctggcac gtcagcctcc
      361 ctggccatca gtgggctcca gaccgaggat gaggctgatt attactgcgc agcatgggat
      421 gatagcctga gcggttacat cttcgctgct gggacccggc tcaccgtcct aggtcagccc
      481 aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01001146             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:18605:24330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001146
VERSION     KCWK01001146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18605:24330"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66884.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          157 c          126 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag cagcactcat ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattac tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001147             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:10239:13503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001147
VERSION     KCWK01001147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:10239:13503"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66885.1"
                     /translation="DYYCQVWDTSIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          146 c          128 g           97 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtgag ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct atactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaagt attgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001148             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:12692:12506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001148
VERSION     KCWK01001148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12692:12506"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..454
                     /note="immunoglobulin light chain variable region"
     V_region        109..454
     V_segment       109..417
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66886.1"
                     /translation="DYHCQVYDGSAVLF"
     J_segment       421..454
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           88 a          166 c          125 g          113 t
ORIGIN      
        1 acatgggggc ccaaccctgg gtctgtggcc tcagaggtag ccgtgtccac catggccctg
       61 actcctctcc tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg
      121 actcagccac cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg
      181 agtagtgacc tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc
      241 gctcccaggt tattcctgta ctacttctcc gactcagaca agcagttggg acctggggtc
      301 cccaatcgag tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct
      361 gggctccagc ctgaggacga ggccgattat cactgtcagg tgtatgacgg tagtgctgtt
      421 ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCWK01001149             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:20685:7619
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001149
VERSION     KCWK01001149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20685:7619"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66887.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       391..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          141 c          137 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ttctgcggcc tcctatgatc tgactcagcc
      121 accctcgatt tcagcgtccc caggacagac ggccagggtc acctgtgggg gagacaacat
      181 cggaggtgaa gttgtgaatt ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatggtgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacgcggcc accctgacca tcagcggggt cgaggccgga gatgaggctg actattactg
      361 tcaggtgtgg gaccttaata gtcatcatct cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001150             498 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:3186:14099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001150
VERSION     KCWK01001150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 498)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:3186:14099"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..460
                     /note="immunoglobulin light chain variable region"
     V_region        112..460
     V_segment       112..423
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <388..>432
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66888.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       424..460
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        461..>498
                     /gene="IGLC"
BASE COUNT          107 a          158 c          113 g          120 t
ORIGIN      
        1 acatggggac cgcagcctga ttgtgactct tctggcaaag atccctgaaa aatttgaccc
       61 tggtttctgc cttagcatcc aataatgtct gtgtttgcag gttccctctc caagcctatg
      121 ctgactcagc cggcctccct ctcagcaact cctggagcat cagccagtct cacatgcacc
      181 ttcagcggtg gcatcaatgt tgctgcctac cacatacact ggtaccagca gaagccaggg
      241 agtccccccc ggtatcttct gagttacaaa tcagactcag ataagggcca gggctctgga
      301 gtccccagcc gcttctctgg atccaaaaat gcttcaacaa acacaggcat tttacacatc
      361 tctgggctcc agtctgagga tgaggctgac tatttctgtg ccattggaca cagcagcggt
      421 ccttacatct tcggtgctgg gacccggctc accgtcctag gtcagcccaa ggcttccccc
      481 acggtcactc tgttcccg
//
LOCUS       KCWK01001151             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22587:19849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001151
VERSION     KCWK01001151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22587:19849"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66889.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           92 a          159 c          121 g          108 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctgact accacataca ctggtaccag cagaagccag ggagtccccc ccggtatctt
      241 ctgagataca gatcagactc agataagggc cagggctctg gagtccccag ccggttctct
      301 ggatccaaag atgctgcagc gaacacaggg attttacgca tctctgggct ccagtctgag
      361 gatgaggctg actattactg tgccattggg cacagcagcg gtccttactt cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01001152             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18230:10052
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001152
VERSION     KCWK01001152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18230:10052"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66890.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       407..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          152 c          129 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgttgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaacatc ggggcgggtt tttatgtttc ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctttgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattat tgttcatcat gggaaagcag cctgaattgg gtattcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001153             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:7298:13618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001153
VERSION     KCWK01001153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7298:13618"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66891.1"
                     /translation="DYFCAAWDDSLTGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          156 c          118 g          105 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cctcctcacc ctcctcactc actgtgcagg gtccagggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtcaccatc tcctgttctg gaaccagctc
      181 caacatcgga agtaatagtg tgtcctggta ccagcagctc ccagaaacgg ctcccaaact
      241 cctcatctat tataatcatc ggcgagcctc aggtgtctct gaccgattct ctggctccaa
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 tttctgcgca gcatgggatg atagcctgac cggttacatt ttcggtcctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001154             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:7066:10069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001154
VERSION     KCWK01001154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:7066:10069"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66892.1"
                     /translation="DYYCQVWDTSIDHGLF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           92 a          146 c          128 g           96 t
ORIGIN      
        1 actggggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtgaggg agacaacatt
      181 ggaagtcaaa gtgtgcactg gtaccagcac aagccaccgc aggcccctat actggtcatc
      241 ttttattata ccgaacggcc ctcaggaatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acacaagtat tgatcacggc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001155             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:7236:17563
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001155
VERSION     KCWK01001155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7236:17563"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66893.1"
                     /translation="AYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          157 c          128 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcgggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcggtgggct ccagaccgag
      361 gatgaggctg cttattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001156             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:19047:4950
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001156
VERSION     KCWK01001156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:19047:4950"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66894.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       410..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           84 a          164 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta cttctactcc gactcagaca agcagctggg ccctggggtc cccgatcgcg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtc ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001157             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:11347:16601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001157
VERSION     KCWK01001157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:11347:16601"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66895.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          163 c          122 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 cattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001158             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:20519:11955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001158
VERSION     KCWK01001158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20519:11955"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66896.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          138 c          136 g          103 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggaaaga cggccaggat cacctgtggg ggagacaata
      181 ttggaagtga agttgtcaac tggtaccagc agaagccacc gcaggcccct gtggtggtca
      241 tctatgctga ttatgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcggag tcgaggccgg ggatgaggct gactattact
      361 gtcaggtttg ggacatttat attgatcatc cggtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001159             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:23589:15155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001159
VERSION     KCWK01001159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:23589:15155"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66897.1"
                     /translation="DYYCQTWETGIVLF"
     J_segment       397..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           89 a          162 c          121 g           99 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaaactca cctgcactct gaacagtggg
      181 cacagcagct acaccatcgc gtggcatcag caacagcaag ggaaggcccc ccggtacttg
      241 atgtggctta aaactgatgg cagccatagc aagggggacg ggatccctga tcgcttctca
      301 ggctccagtt ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggaaact ggcattgtgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001160             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:25950:22534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001160
VERSION     KCWK01001160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:25950:22534"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66898.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          148 c          131 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgggc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001161             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:15205:11913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001161
VERSION     KCWK01001161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:15205:11913"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66899.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ctg
//
LOCUS       KCWK01001162             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:14420:22479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001162
VERSION     KCWK01001162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14420:22479"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66900.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          162 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001163             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:19103:5149
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001163
VERSION     KCWK01001163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19103:5149"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..430
                     /note="immunoglobulin light chain variable region"
     V_region        99..430
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66901.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       410..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>478
                     /gene="IGLC"
BASE COUNT           84 a          162 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta cttctactcc gactcagaca agcagctggg acctggggtc cccgatcgcg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtc ttattcggag
      421 gagggacccg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001164             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:14733:18513
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001164
VERSION     KCWK01001164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14733:18513"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66902.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          147 c          130 g           96 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gtactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001165             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:23668:3091
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001165
VERSION     KCWK01001165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23668:3091"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..399
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66903.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       403..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          163 c          117 g          105 t
ORIGIN      
        1 acatggggcc tcagaggtag ccgtgtccac catggccctg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagcctc cctccctgtc
      121 tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc tcagtgttgg
      181 tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt tattgctgta
      241 ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag tctctggctc
      301 caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc ctgaggacga
      361 ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001166             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:17939:10394
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001166
VERSION     KCWK01001166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17939:10394"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66904.1"
                     /translation="DYYCALWYNSAWIF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          157 c          116 g          114 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctgt cacagcctgt gctgactcag ccggcctccc
      121 tctcagtatc tcctggaaca tcagtcagac tcacctgcac cttgcgcact ggcgtcaatg
      181 ttggtggctc ctacatattc tggtaccaac agaggccagg tcgtcctccc cggtaccttc
      241 tgaactacta ctcagactca aataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcaggac ttttactgat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccttatggt acaacagcgc ttggatattc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001167             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:18750:14188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001167
VERSION     KCWK01001167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18750:14188"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66905.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          160 c          124 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gcctgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagag gccagggagc gctcccaggt
      241 tattcctgta ttactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaggtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001168             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:24325:23131
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001168
VERSION     KCWK01001168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24325:23131"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66906.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          148 c          131 g           96 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atcccggagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001169             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:14502:9738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001169
VERSION     KCWK01001169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14502:9738"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66907.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           88 a          160 c          120 g          108 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc gtcaatgtgg
      181 gttattacag catattctgg taccagcaga agccagggag tcctccccgg taccttctgt
      241 actaccagtc agactcaagg aagcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggctgt tactgatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc ctatggcaca gcagcgcttc ttgcatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001170             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:16956:16675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001170
VERSION     KCWK01001170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16956:16675"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66908.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       396..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          157 c          121 g          101 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct cgtctcctct
       61 cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc tgacacagcc
      121 gccctcagtg tctggggccc cagggcagag ggtcaccatc tcctgcactg ggagcagctc
      181 caacattgga ggttattata tatcctggta ccagcagctc ccaggaacgg cccccaaact
      241 cctcgtctat gacaataata agcgaccctc aggggtttct gaccgattct ctggctccaa
      301 gtctggttcc tcagccaccc tgaccatcac tgggctccag actgaggatg aggctgatta
      361 ttactgccag tcctatgaca gcagtctgag tgctcgggta ttcggcggag ggacccggct
      421 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001171             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11189:12333
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001171
VERSION     KCWK01001171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11189:12333"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66909.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       390..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           86 a          139 c          136 g          101 t
ORIGIN      
        1 acatggggga ctttgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctttacaggc tctgtggcct cctatgagtt gcctcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtaata gtgtgcattg gtaccagcag aagccaccgc gggcccctgt attggtcatc
      241 tctgttgata gcgaacggcc ctcagggatc cctgagcgat tctctggttc cagatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg ataatattta taaatacgcg gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001172             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:2858:16312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001172
VERSION     KCWK01001172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:2858:16312"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..433
                     /note="immunoglobulin light chain variable region"
     V_region        106..433
     V_segment       106..393
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66910.1"
                     /translation="DYYCDSWDTTGTHPVLF"
     J_segment       396..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           92 a          149 c          127 g          103 t
ORIGIN      
        1 acatggggag ctgtgggctc agaagcagag ctctggggtg tctccaccat ggcctggact
       61 cctctctggc tcaccctcct cagtctttgc acaggttctg tggtttcctc tggcctgact
      121 caggaccctg cagtgtctgt ggccttggga cagactgtca ggatcacctg ccaaggagac
      181 agcctcagaa ccagttatgc aagctggtac cagcagaagc caggccaggc ccctgtcctg
      241 gtcgtctatg gtaacaacta ccggccctca gggatcccag agcgattctc tggctccaac
      301 tcaagaaaca cagcttcctt gaccatcact gggactcagg tggaagatga ggctgactat
      361 tactgtgact cctgggacac caccggtacc catcctgtgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001173             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:16377:17661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001173
VERSION     KCWK01001173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16377:17661"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66911.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          149 c          128 g           97 t
ORIGIN      
        1 acatgggctg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gtactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001174             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:22105:17787
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001174
VERSION     KCWK01001174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22105:17787"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66912.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       411..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          164 c          121 g          107 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cactgacctc
      181 agtgttggtg gtaaaaacat gtactggtac cagcagaagc caggaagcgc tcccaggtta
      241 ttgctgtatt accactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcaggtg tatgacagta gtgccaacac gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001175             358 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:19301:12060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001175
VERSION     KCWK01001175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 358)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 358)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..358
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19301:12060"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..320
                     /note="immunoglobulin light chain variable region"
     V_region        79..320
     V_segment       79..280
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <248..>292
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66913.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       287..320
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        321..>358
                     /gene="IGLC"
BASE COUNT           73 a          112 c           92 g           81 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcact ggtaccacca gaagccaggg agtccccccc ggtatcttct
      121 gagatacaaa tcagactcag ataagggcca gggctctgga gtccccagcc gcttctctgg
      181 atccaaagat gcttcagcga acacagggat tttacacatc tctggactcc agtctgagga
      241 tgaggctgac tattactgtg ccattggaca cagcagcggt gattatatct tcggtggtgg
      301 gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01001176             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:7520:12518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001176
VERSION     KCWK01001176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:7520:12518"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..398
                     /note="immunoglobulin light chain variable region"
     V_region        74..398
     V_segment       74..361
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <323..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66914.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       362..398
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>436
                     /gene="IGLC"
BASE COUNT           83 a          141 c          119 g           93 t
ORIGIN      
        1 acatggggcc tcagccatgg cctggacttt tctcctcctc ggcctccttg cttactgcac
       61 aggctctgcg gcctccgatg atctgactca gccaccctcg gtgtcagtgt ccccaggaca
      121 gacggccagg atcacctgtg ggggagacaa cattggaagt aagagtgtgc actggtacca
      181 gcacaagcca ccgcaggccc ctatcctggt catctattat tataccgaac ggccctcggc
      241 gatccctgag cgattctctg gctccaaatc agggaacacc gccaccctga ccatcagcgg
      301 ggtcgaggcc ggggatgagg ctgactatta ctgtcaggtg tgggacacta ctattgatca
      361 tggctttttc ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      421 ggtcactctc ttcccg
//
LOCUS       KCWK01001177             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:25360:15495
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001177
VERSION     KCWK01001177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:25360:15495"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66915.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          147 c          130 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcgacc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001178             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:3747:7722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001178
VERSION     KCWK01001178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:3747:7722"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66916.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       396..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          150 c          138 g           94 t
ORIGIN      
        1 acatgggggg tctgggtctc aggaggcagc attgacggtg cctcagccat ggcctggacc
       61 cttctcctcc tcggcctcct cgctcactgc acaggctctg cgacctccta tgagctgact
      121 cagccaccct cggtgtcagc ggcctcagga cagacggcca ggatcccctg tgggggagac
      181 aacattggaa ctaaatatgt gcactggtac cagcagaagc cagcgcaggc ccctgtgttg
      241 gtcatctatg ctgataccag acggccctca gggatccctg agcgattctc tggctccaac
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccgggtatga ggctgactat
      361 ttctgtcagg tgtgggacga tagtagtgat catccggtat tcggcggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001179             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:12647:19889
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001179
VERSION     KCWK01001179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12647:19889"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66917.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          162 c          120 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001180             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:9781:9807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001180
VERSION     KCWK01001180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:9781:9807"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..330
                     /note="immunoglobulin light chain variable region"
     V_region        8..330
     V_segment       8..289
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <255..>302
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66918.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       293..330
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        331..>368
                     /gene="IGLC"
BASE COUNT           76 a          117 c           92 g           83 t
ORIGIN      
        1 acatggggct gactcagcct ccctcagcgt ctgaggccgc caggaagagt gtcaccatct
       61 cctgttctgg aagcagctcc aacatcggaa gtaataatgt gtcctggtac cagcacctcc
      121 caggaacagc tcccaaactc ctcatctatt ataatgatca acgaggctca ggtgtctctg
      181 accgattctc tggctccaag tctggcacgt cagcctccct ggccatcagt gggctccaga
      241 ccgaggatga ggctgattat tactgcgcag cgtgggatga tagcctgagt agttacatct
      301 tcgctgctgg gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      361 tgttcccg
//
LOCUS       KCWK01001181             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:16403:11613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001181
VERSION     KCWK01001181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16403:11613"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..432
                     /note="immunoglobulin light chain variable region"
     V_region        103..432
     V_segment       103..396
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66919.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       401..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>471
                     /gene="IGLC"
BASE COUNT           95 a          157 c          114 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagttcca gggtcctggg cccagtctgt gctgactcag
      121 ccaccctcag cgtctgggac tcccgggcag agtgtcacca tctcgtgctc tggaagcagc
      181 tccaacattg gaactaatta tgtatactgg taccaacacc tcccaggaac ggcccccaaa
      241 ctcctcatct attatagtaa tcagcgaccc tcaggggtcc ctgaccgatt ctctggctct
      301 aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga tgaggctgat
      361 tattactgtg cagcatggga taacagcctg accagtccgg tattcggagg agggacccgg
      421 ctgaccgtcc taagtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001182             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:5760:11399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001182
VERSION     KCWK01001182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5760:11399"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66920.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          141 c          138 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctgg gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001183             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:7548:5755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001183
VERSION     KCWK01001183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:7548:5755"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66921.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       410..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          156 c          129 g          107 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcctcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata gtgtttcctg gtaccagcag ctcccagaaa
      241 cggctcccaa actcctcatc ttttataatg atcggcgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagcggtccg gtattcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001184             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:20847:6046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001184
VERSION     KCWK01001184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20847:6046"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66922.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          140 c          135 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaggccaccg caggcccctg tgttggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001185             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:21055:7903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001185
VERSION     KCWK01001185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21055:7903"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66923.1"
                     /translation="DYFCGAAYGSGSSWQWVF"
     J_segment       395..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           94 a          148 c          131 g           96 t
ORIGIN      
        1 acatggggct ggcttcagaa gcagcatctg ggacatgtca gccatggcct ggacgcctct
       61 cctcctcagc ctcctcgctc actgcacagg ctctgtggcc tcctatgagc tgactcagcc
      121 accctcagtg tcggtgtccc caggacagac agccagcatc acctgctctg gaaataaatt
      181 ggggaatgta tatacttact ggttccagca gaagccaggc caggccccta tagtggtcat
      241 ctacaaagat accaaccggc cctcagggat ccctgagcga ttctctggct ccgactcagg
      301 gaacacggcc accctgacca tcagcagggt cgaggctggg gatgaggccg actatttttg
      361 tggtgcagcc tatggcagtg gcagcagctg gcagtgggta ttcggcggag ggacccggct
      421 aatcgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001186             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:17784:16196
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001186
VERSION     KCWK01001186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:17784:16196"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66924.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       404..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           86 a          161 c          126 g          105 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagccgcgc tcagtgtctg ggtctccagg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc gtgatttatg aggtcaatca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct ggcctccagc ctgaggacga
      361 ggctgattat tactgcagtt catatgcagg cagcgacact ttcgtgttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001187             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:11447:3737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001187
VERSION     KCWK01001187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11447:3737"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66925.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           98 a          160 c          111 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgttgccta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagttacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaaa tggttcaaca aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattggac acagcagcgg tccttacatc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001188             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:6754:8826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001188
VERSION     KCWK01001188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6754:8826"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..252
                     /note="immunoglobulin light chain variable region"
     V_region        9..252
     V_segment       9..213
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <177..>224
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66926.1"
                     /translation="DYYCGAWDSSLSGYIF"
     J_segment       215..252
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        253..>290
                     /gene="IGLC"
BASE COUNT           58 a           88 c           77 g           67 t
ORIGIN      
        1 acatgggggg gagaaattct gtctcctggt accagcaggt cccaggaacg gcccccaaac
       61 tcctcagcta tgacaatgat aagcgaccct caggggtttc tgaccgattc tctggctcca
      121 agtctggttc ctcagcctcc ctggccatca ctggactcca gactggagat gaggctgatt
      181 attactgcgg agcatgggat agcagtctga gtggttacat tttcggtgct gggacccgac
      241 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01001189             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:11884:6599
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001189
VERSION     KCWK01001189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11884:6599"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66927.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          158 c          120 g          107 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgactacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 gatacagatc agactcagat aagggccagg gctctggagt ccccagccgg ttctctggat
      301 ccaaagatgc tgcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtcc ttacttcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001190             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:16824:3730
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001190
VERSION     KCWK01001190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16824:3730"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66928.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          160 c          111 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagaaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001191             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:9025:18413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001191
VERSION     KCWK01001191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9025:18413"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66929.1"
                     /translation="DYYCCSYRTGNSWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          157 c          127 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac caacagcact cagggacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tattgttgct catataggac tggaaacagt tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001192             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:6049:5785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001192
VERSION     KCWK01001192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:6049:5785"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..386
                     /note="immunoglobulin light chain variable region"
     V_region        63..386
     V_segment       63..347
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <314..>358
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66930.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       352..386
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        387..>424
                     /gene="IGLC"
BASE COUNT           83 a          135 c          105 g          101 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcccctctca gcatctccgg gagcatcagt cagactcagc tgcaccttga gcagtggcat
      121 caatgttggt tcttacacca tattctggta ccagcagaag ccagggagtc ctccccggtt
      181 ccttctgtac tactactcag actcaaataa tcaccagggc tctggagtcc ccagccgctt
      241 ctctggatcc aaagatgctt cagccaatgc agggctttta ctgatctctg ggctccagtc
      301 tgaagatgag gctgactatt actgtgccat gtggcacagc agcgcttatg ccttattcgg
      361 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      421 cccg
//
LOCUS       KCWK01001193             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:11003:5992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001193
VERSION     KCWK01001193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11003:5992"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66931.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          160 c          123 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gaaataaaaa catatactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtcat acagcgtttt tgctcatttc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgacg atagtgctgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001194             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:8160:7504
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001194
VERSION     KCWK01001194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8160:7504"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66932.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          161 c          115 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 ctgcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatataaatc agactcagat aacgaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ctcagcgaac acgggacttt tgcgcatctc tgggctccag tctgaggatg
      361 aggctgacta ctactgtgcc attggacaca gcagcggtga ttacatcttc ggtgctggga
      421 cccgcctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001195             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:16604:19413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001195
VERSION     KCWK01001195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16604:19413"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66933.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          151 c          122 g          114 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcagga cacaggatcc tgggttcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat gttgggtatt ataacgctgt gtcttggtac caacagcatc caggcaaagc
      241 ccccaaactc atgatttatg acgtcattaa gcggccctca ggggtttctg atcgcttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagaaataat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001196             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:7123:12660
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001196
VERSION     KCWK01001196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7123:12660"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66934.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       402..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           93 a          155 c          120 g          109 t
ORIGIN      
        1 acatgggggg tggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc aagcctatgc tgactcagcc ggcctccctc
      121 tcagcatctc ctggaacatc agccagtctc acatgcacct tcagcggtgg catcaatgtt
      181 gttggctacc acatacactg gtaccagcag aagccaggga gtcctccccg gtatcttctg
      241 agatacaaat cggactcaga taagggccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcagcgaa cgcagggatt ttacgcatct ctggactcca gtctgaggat
      361 gaggctgact attactgtgc cattgggcac agcagcggtg attacatctt cggtgctggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01001197             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:12740:11483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001197
VERSION     KCWK01001197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12740:11483"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66935.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       400..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           90 a          155 c          122 g          107 t
ORIGIN      
        1 acatggggct ggggtctcag gaggcggcac tctcgggaca tctccaccat ggcctgggat
       61 ctgctcctct tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagcctccct caatgtctgg gtctcctgga cagtcggtca ccatctccta cactggaacc
      181 agcagtgaca ttggtggtta taaccgtgtc tcctggtacc aacagcaccc aggcaaagac
      241 cccaaattca tgatttatga ggtcagtcaa cggccctcag gggtctctga tcgtatctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccagac tgaggatgag
      361 gctggttatt actgcagctc atttgcaggt accaacactg gcttaatcgg tggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001198             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:23113:11432
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001198
VERSION     KCWK01001198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:23113:11432"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66936.1"
                     /translation="DYHCQVFDSSDVLF"
     J_segment       414..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          161 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tgataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctacttctcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtttgacag tagtgatgtt ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001199             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:2742:15736
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001199
VERSION     KCWK01001199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:2742:15736"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..455
                     /note="immunoglobulin light chain variable region"
     V_region        110..455
     V_segment       110..418
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66937.1"
                     /translation="DYHCQVYDSSAVLF"
     J_segment       419..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           90 a          169 c          125 g          109 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      181 gagcagtgac ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag
      241 cgctcccagg ttattcctgt actacttctc cgactcagac aagcagctgg gacctggggt
      301 ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgttct tgctcatctc
      361 tgggctccag cctgaggacg aggccgatta tcactgtcag gtgtatgaca gtagtgctgt
      421 gttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01001200             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:9830:19170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001200
VERSION     KCWK01001200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9830:19170"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66938.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       399..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           96 a          152 c          110 g          116 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcgcag cctgtgctga ctcagccaac ctccctctca
      121 gcatctcctg gagcatcagc cagactcacc tgcaccttga acagtggcat cagtgttgct
      181 aattacagga tattctggta ccaccagaag ccagggagtc ctccccggta tcttctgaac
      241 taccacacag actcagatat tcatcagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cggccaatgc agggatttta ctcatctctg gactccagtc tgaggatgag
      361 gctgactatt actgtatgat ttggcacaac aatgcttatt gggttttcgg cggagggacc
      421 cggctaaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001201             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:15820:8460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001201
VERSION     KCWK01001201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15820:8460"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66939.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          159 c          121 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gttcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcaga tgtatgacag tagtgatgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001202             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:17092:1941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001202
VERSION     KCWK01001202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17092:1941"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..433
                     /note="immunoglobulin light chain variable region"
     V_region        88..433
     V_segment       88..396
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66940.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           93 a          158 c          110 g          110 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttga gcagtggcaa tgttggtagt
      181 tacagcatat tctggtacca gcagaagcca gggagtcctc cccggtacct tctttactac
      241 tactcagact caagtaacca ccaggactct ggagtcccca gccgcttctc tggatcgaaa
      301 gatgcttcag ccaatgcagg gcttttactg atctctgggc tgcagtctga agatgaggct
      361 gactattact gtgccacatg gcacagcagc gcttcttaca tcttcggtac tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01001203             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:15314:15755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001203
VERSION     KCWK01001203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15314:15755"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66941.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          158 c          127 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtggt gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcactct gagtagtgac
      181 ctcagtgttg gtggtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt tctaccagtc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tggactccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgcaaa tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01001204             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:13281:6473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001204
VERSION     KCWK01001204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13281:6473"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..437
                     /note="immunoglobulin light chain variable region"
     V_region        93..437
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66942.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>479
                     /gene="IGLC"
BASE COUNT           91 a          154 c          119 g          115 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagct tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacttatat tggtaccagc agaagccagg gagtcccccc cggtttcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagtagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtcata ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001205             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:11563:9105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001205
VERSION     KCWK01001205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11563:9105"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66943.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          161 c          124 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg tacctgcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaaataac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctaa tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01001206             279 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:19049:9232
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001206
VERSION     KCWK01001206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 279)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19049:9232"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..241
                     /note="immunoglobulin light chain variable region"
     V_region        7..241
     V_segment       7..204
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <172..>213
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66944.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       205..241
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        242..>279
                     /gene="IGLC"
BASE COUNT           53 a           85 c           83 g           58 t
ORIGIN      
        1 acatgggcat ggcatcagca gcaacaaggg aaggcccctc ggttcttgat gtggcttaag
       61 agtgatggca gccacaccaa gggggacggg gtccctgatc gcttctcagg ctccagctcc
      121 ggggctgagc gctacctcac catctccaac ctccggtctg aggatgaggc tgattattac
      181 tgtcagacct gggacattgg catttgggta ttcggcggag ggacccggct aaccgtccta
      241 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001207             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:13942:4255
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001207
VERSION     KCWK01001207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13942:4255"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66945.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          162 c          109 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcttcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001208             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:19531:12552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001208
VERSION     KCWK01001208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19531:12552"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66946.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          162 c          108 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt tagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaagt aaacaccagg gctctagagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001209             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:20502:4098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001209
VERSION     KCWK01001209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20502:4098"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66947.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           95 a          161 c          111 g          107 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcaactcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 gcctaccaca tacactggta ccaacagaag ccagggagtc ccccccggta tcttctgagt
      241 tacagatcag actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaaaatgctt caacgaacac aggcatttta cacatctctg ggctccagtc tgaggatgag
      361 gctgactatt tctgtgccat tggacacagc agcggtcctt acatcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001210             283 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:20993:12217
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001210
VERSION     KCWK01001210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 283)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20993:12217"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..245
                     /note="immunoglobulin light chain variable region"
     V_region        8..245
     V_segment       8..208
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <170..>217
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66948.1"
                     /translation="DYFCQVWDDSTDHPVF"
     J_segment       215..245
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        246..>283
                     /gene="IGLC"
BASE COUNT           54 a           88 c           83 g           58 t
ORIGIN      
        1 acatgggaaa tatgtgcact ggtaccagca gaagccagcg caggcccctg tgttggtcat
       61 ctatgctgat accagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      121 gaacaccgcc accctgacca tcagcggggt cgaggccggg tatgaggctg actatttctg
      181 tcaggtgtgg gacgatagta ctgatcatcc ggtcttcggc ggagggaccc ggctgaccgt
      241 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001211             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:18145:19831
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001211
VERSION     KCWK01001211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18145:19831"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..408
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66949.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           93 a          164 c          113 g          115 t
ORIGIN      
        1 acatggggag tcccactgca gggaaagagg ctgtgtccac catggcctgg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg acccagccaa
      121 cctccctctc agcatctccg ggagcatcag tcagactcag ctgcaccttg agcagtggca
      181 tcaatgttgg ttcttacacc atattctggt accagcagaa gccagggagt cctccccggt
      241 tccttctgta ctactactca gactcaaata atcaccaggg ctctggagtc cccagccgct
      301 tctctggatc caaagatgct tcagccaatg caggcctttt actgatctct gggctccagt
      361 ctgaagatga ggctgactat tactgtgcca tgtggcacag cagcgcttat gccttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001212             305 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:7896:3319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001212
VERSION     KCWK01001212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 305)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:7896:3319"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..267
                     /note="immunoglobulin light chain variable region"
     V_region        8..267
     V_segment       8..228
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <195..>239
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66950.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       230..267
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        268..>305
                     /gene="IGLC"
BASE COUNT           66 a           89 c           74 g           76 t
ORIGIN      
        1 acatgggtgc taattacagg atattctggt accaccagaa gccagggagt cctccccggt
       61 atcttctgaa ctaccacaca gactcagata ttcaccaggg ctctggagtc cccagccgct
      121 tctctggatc caaagatgct tcggccaatg cagggatttt actcatctct ggactccagt
      181 ctgaggatga ggctgactat tactgtatga tttggcacaa caatgcttat tgggttttcg
      241 gcggagggac ccggctaacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      301 tcccg
//
LOCUS       KCWK01001213             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:14019:9591
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001213
VERSION     KCWK01001213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14019:9591"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66951.1"
                     /translation="DYYCAAWDDSLYGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          152 c          119 g          102 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagga atagtgtatc ctggtaccag caggtcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagcggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgtacggt tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001214             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:10452:9455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001214
VERSION     KCWK01001214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10452:9455"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66952.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          162 c          111 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagttgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacta ctcagactca agtaagcacc aggcctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctggggtc cagtctgaag
      361 atgacgctga ctattactgt gccacatggc acagcagcgc ttcttacatc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001215             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:14440:3654
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001215
VERSION     KCWK01001215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14440:3654"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66953.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          152 c          120 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001216             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:22434:13845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001216
VERSION     KCWK01001216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22434:13845"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66954.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          155 c          128 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccaa cagcttccag
      241 gaacggcccc caaactcctc atctatgaaa atgataaacg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct gattcctcag cctccctgac cgtcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cttgagtgtt gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001217             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:23433:9866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001217
VERSION     KCWK01001217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:23433:9866"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66955.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          156 c          117 g          115 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcaag ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg gcagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtctt ataatgctgt gtcttggtac caacaacatc caggcaaagc
      241 cccccaactc ataatttttg aggtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatttct gggctccagg ctgaggatga
      361 ggctgattat tactgctgct catatgtagg cagcaacact tacatcttcg atgttgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001218             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:20203:4383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001218
VERSION     KCWK01001218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20203:4383"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..403
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66956.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       408..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           97 a          154 c          113 g          116 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcgcagcctg tgctgactca gccaacctcc
      121 ctctcagcat ctcctggagc atcagccaga ctcacctgca ccttgagcag tggcttcagt
      181 gttggtactt acaggatatt ctggtaccag cagaagccag ggagtcctcc ccggtatctt
      241 cttaactacc acacagactc agataaacac caggactctg gagtccccag ccgcttcttt
      301 ggatccaaag atgctccggc caatgcaggg attttactca tctctgggct ccagtctgag
      361 gatgaggctg actattactg tatgatttgg cacaacaatg cttatgtctt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001219             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15657:12609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001219
VERSION     KCWK01001219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15657:12609"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..439
                     /note="immunoglobulin light chain variable region"
     V_region        94..439
     V_segment       94..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66957.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       403..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           94 a          163 c          109 g          111 t
ORIGIN      
        1 acatggggca ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggaac atcagccaga ctcagctgca ccttgagcag tggcaatgtt
      181 ggtagttaca gcatattctg gtaccagcag aagccaggga gtcctccccg gtaccttctt
      241 tactactact cagactcaag taaccaccag gactctggag tccccagccg cttctctgga
      301 tcgaaagatg cttcagccaa tgcagggctt ttactgatct ctgggctcca gtctgaagat
      361 gaggctgact attactgtgc cacatggcac agcagcgctt cttacatctt cggtcctggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01001220             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:7887:8072
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001220
VERSION     KCWK01001220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:7887:8072"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66958.1"
                     /translation="DYYCAAWDESLRGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          152 c          121 g           98 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg cgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctgggag cagctccaac
      181 atcggaagaa atagtgtatc ctggtaccag cagctcccag gaacagctcc caaaatcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag ccgccctggc catcagcggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgaaag cctgaggggt tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001221             453 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:15404:20022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001221
VERSION     KCWK01001221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 453)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15404:20022"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..415
                     /note="immunoglobulin light chain variable region"
     V_region        91..415
     V_segment       91..378
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <340..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66959.1"
                     /translation="DYYCQSSHSRVNHPFF"
     J_segment       385..415
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>453
                     /gene="IGLC"
BASE COUNT          102 a          136 c          119 g           96 t
ORIGIN      
        1 acatggggga ggaagacctc tgggtgtctc accatgacct ggaccactgt tctgctcccc
       61 tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc accctcagtg
      121 tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaacact ggcaaaaaaa
      181 tatgctcagt ggttccagca gaagccaggc caggcccctg tgttggtgat atataaagac
      241 agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg gacaacagtt
      301 accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg tcaatcatcg
      361 cacagcaggg ttaatcatcc gtttttcgga ggagggaccc ggctgaccgt cctaggtcag
      421 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001222             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:19614:20267
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001222
VERSION     KCWK01001222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19614:20267"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66960.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          163 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactcctcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001223             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20225:16234
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001223
VERSION     KCWK01001223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20225:16234"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66961.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          163 c          121 g          109 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtaataaaaa catgtactgg taccaacaga agccagggag cgctcccagg
      241 ttattcctgt actactattc cgactcagac aagcagctgg gacctggggt cccccatcga
      301 gtctctggct ccaaggagac ctcaactaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ctactgtcag gtgtatgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001224             359 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:13375:7042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001224
VERSION     KCWK01001224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 359)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 359)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13375:7042"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..321
                     /note="immunoglobulin light chain variable region"
     V_region        10..321
     V_segment       10..286
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <249..>293
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66962.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       291..321
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        322..>359
                     /gene="IGLC"
BASE COUNT           72 a          110 c           90 g           87 t
ORIGIN      
        1 acatggggac tccctctgtg tccgggtctc ctggacagtc ggtcaccatc tcctgcagtg
       61 gaaccagcag tgatattggg tattatcatg ctgtgtcttg gtaccaacat catccaggca
      121 aagcccccaa actcatgatt tttgaggtca ataaacggcc cgcaggggtc tctgatcgct
      181 tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc cagactgagg
      241 atgaggctga ttattactgc agctcatatg caggcagcaa cactttattc ttcggaggag
      301 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001225             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:15569:7826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001225
VERSION     KCWK01001225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15569:7826"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66963.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       401..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          153 c          114 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcatctcc tggagcatca gccagactca cctgcacctt gaacagtggc atcagtgttg
      181 gtaattacag gatattctgg taccaccaga agccagggag tcctccccgg tatcttctga
      241 actaccacac agactcagat attcaccagg gctctggagt ccccagccgc ttctctgggt
      301 ccaaggatgc ttcggccaat gcagggattt tactcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtatg atttggcaca acaatgctta ttgggtattc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001226             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11253:16854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001226
VERSION     KCWK01001226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11253:16854"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66964.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       414..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          164 c          119 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atttactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgcg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtattattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001227             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:6209:15485
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001227
VERSION     KCWK01001227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6209:15485"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..252
                     /note="immunoglobulin light chain variable region"
     V_region        8..252
     V_segment       8..215
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <177..>224
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66965.1"
                     /translation="DYYCQSADSSSHHYIF"
     J_segment       219..252
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        253..>290
                     /gene="IGLC"
BASE COUNT           71 a           78 c           75 g           66 t
ORIGIN      
        1 acatggggga aaaaaaatat actcagtggt tccagcggaa gccaggccag gcccctgttt
       61 tggtgatcta taaagacagt gagaggccct cagggatccc tgagcgattc tctagttcca
      121 gttcagggac aacagttacc ttgaccatca gtggggccca ggcagaagat gaggctgact
      181 attattgtca atcagcagac agtagtagtc atcattatat cttcggtcct gggacccggc
      241 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01001228             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:9258:11489
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001228
VERSION     KCWK01001228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9258:11489"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..440
                     /note="immunoglobulin light chain variable region"
     V_region        94..440
     V_segment       94..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66966.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       408..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>480
                     /gene="IGLC"
BASE COUNT           89 a          164 c          114 g          113 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcaccaat
      181 gttggtagtt acagcatttt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
      241 ctctactact actcagactc aactaagcac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgattcagc caatgcaggg cttttactga tctctgggct ccagtctgag
      361 gatgaggctg actattactg tgccatttgg cacagcagcg cttcttgcat cttcggtcct
      421 gggacccggc tcaccgtcct gggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01001229             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:16894:12094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001229
VERSION     KCWK01001229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16894:12094"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..418
                     /note="immunoglobulin light chain variable region"
     V_region        91..418
     V_segment       91..378
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66967.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       382..418
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>456
                     /gene="IGLC"
BASE COUNT           87 a          140 c          129 g          100 t
ORIGIN      
        1 acatggggag gcagcattga cggtgcctca gccatggcct ggacttttct cctcctcggc
       61 ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc accctcggtg
      121 tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat tggaagtgaa
      181 gttgtcaact ggtaccaaca gaagccaccg caggcccctg tggtggtcat ctatgctgat
      241 tatgaacggc cctcagggat ccctgaccga ttctctggct ccaaatcagg gaacacggcc
      301 accctgacca tcagcggagt cgcggccggg gatgaggctg actattactg tcaggtttgg
      361 gacatttata ctgatcatcc ggtgttgttc ggaggaggga cccggctgac cgtcctaggt
      421 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001230             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:7022:15750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001230
VERSION     KCWK01001230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:7022:15750"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66968.1"
                     /translation="DYYCQVWDSSSDHYIF"
     J_segment       392..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          148 c          132 g           94 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctatgaac tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccagggtc acctgtgggg gagacaacat
      181 tggaactacg tttgtgcact ggtaccagca gaatccaccg caggcccctg tgcaggtcat
      241 ctttgcggat aacaaacggc cctcagggat ccctgaacga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtgatcatta tatcttcggt ggtgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01001231             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:11005:15607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001231
VERSION     KCWK01001231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:11005:15607"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66969.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          162 c          108 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctagagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001232             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:7555:13336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001232
VERSION     KCWK01001232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:7555:13336"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66970.1"
                     /translation="DYFCAIGHNSGDYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          159 c          118 g          108 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttccgcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaaggcagg gagtcctccc cggtatcttc
      241 tgaaatacaa atcggactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattgggc acaacagcgg tgactacatc ttcggcactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001233             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:19148:6939
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001233
VERSION     KCWK01001233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19148:6939"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66971.1"
                     /translation="DYYCHVYDSSSNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          163 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcgtcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctcc gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtagtaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001234             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:16092:14227
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001234
VERSION     KCWK01001234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16092:14227"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66972.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           96 a          147 c          128 g           91 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga actcctatga gctgactcag
      121 ccaccctcag tgtcagcggc ctcaggacag acggccagga tcacctgtgg cggagacaac
      181 attggaatta aaaatgtaca ctggtaccac cagaagccac cgcaggcccc tgtgctggtc
      241 atctttgctg ataacaaacg gccctcaggg atccctgagc gattctctgc ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg gtattcggcg gagggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001235             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:8832:18185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001235
VERSION     KCWK01001235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8832:18185"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66973.1"
                     /translation="DYYCTAWDNSLSSPIF"
     J_segment       399..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           93 a          153 c          116 g          107 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gataatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 accctcagcg tctggggctc ccgggcagag tgtcaccatc tcttgctctg gaagcagctc
      181 caacattgga aataattatg tatactggta ccaacagttc ccaggaatgg cccccaaact
      241 cctcatctat tatagtcgtc agcgaccctc aggggtccct gaccgattct ctgcctctaa
      301 atctggcacc tcagcctccc tggccatcac tggtctccga tctgaggatg aggctgatta
      361 ttactgtaca gcatgggata acagcctgag cagtccgata ttcggcggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001236             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:9656:16270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001236
VERSION     KCWK01001236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9656:16270"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..385
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66974.1"
                     /translation="DYYCQVWDSDSKWVF"
     J_segment       387..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>461
                     /gene="IGLC"
BASE COUNT           91 a          147 c          134 g           89 t
ORIGIN      
        1 acatgggctg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgag ctgactcagc
      121 caccctcagt gtcagcggcc tcaggacaga cggccaggat cacctgtggc ggggacagcc
      181 ttggaacaaa atatgtgcac tggtaccagc agaagccaac gcaggcccct gtggtggtca
      241 tctatgctga taataaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtgat agtaagtggg tcttcggcgg agggacccgg ctaaccgtcc
      421 caggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001237             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:21715:7970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001237
VERSION     KCWK01001237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21715:7970"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66975.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       396..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          145 c          141 g           92 t
ORIGIN      
        1 acacgggggt ggggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgcg ggggagacaa
      181 gattggaagt gaagttgtga actggtacca gcagaagcca gcgcacgccc ctgtgctggt
      241 catctatgct aatagcgaac ggccctcagg gatccctgag cgattctctg gctccaaatc
      301 agggaacacg gccaccctga ccatcagcgg ggtcgaggcc gggggtgagg ctgactatta
      361 ctgtcaggtg tgggacatgc gtagtgatca accgctattc ggcggaggga cccggctaac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001238             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:15177:13324
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001238
VERSION     KCWK01001238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15177:13324"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66976.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          155 c          118 g          114 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacgtacac tggtatcagc agaagtcagg gggtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc tgggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aatacaggga ttttacacat ctctggtttc cagtctgagg
      361 atgaggctga ctattactgt gccattggcc acggcagcgg tgattacatc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001239             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:23144:2652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001239
VERSION     KCWK01001239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23144:2652"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..426
                     /note="immunoglobulin light chain variable region"
     V_region        96..426
     V_segment       96..389
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66977.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          152 c          121 g          102 t
ORIGIN      
        1 atgggggaca gaaggcagga ctcaggataa tctccagcat ggcctggttc cctctcgtcc
       61 tcaccctcct cactcactgt gcagggtcct gggcccagtc tgagctgact cagccaccct
      121 cagcgtctgg ggctcccggg cagagtgtca ccatctcctg ctctggaagc agctccaata
      181 ttggaagtaa ttctgtatac tggtaccagc agttcccagg aacggccccc aaactcctca
      241 tctattatag taatcagcga ccctcagggg tccctgaccg agtctctggc tctaagtcgg
      301 gcacctcagc ctccctggcc atcactggtc tccgatctga ggatgaggct gattattact
      361 gtgcagcatg ggatgacagc ctgagaagtc cgctattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001240             376 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:13548:13678
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001240
VERSION     KCWK01001240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 376)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13548:13678"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    201..338
                     /note="immunoglobulin light chain variable region"
     V_region        201..338
     V_segment       201..302
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <266..>310
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66978.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       306..338
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        339..>376
                     /gene="IGLC"
BASE COUNT           76 a          117 c          109 g           74 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga attgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa ctcagggaac accgccaccc tgaccatcag
      241 cagggtcgag gccggggatg aggctgacta ttactgtcag gtgtgggaca gtagtagtaa
      301 atggatattc ggcgggggga cccggctaac cgtcctaggt cagcccaagg ctgccccctc
      361 ggtcactctc ttcccg
//
LOCUS       KCWK01001241             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:15020:22405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001241
VERSION     KCWK01001241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15020:22405"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66979.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaacc cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001242             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:3651:17779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001242
VERSION     KCWK01001242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:3651:17779"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..263
                     /note="immunoglobulin light chain variable region"
     V_region        9..263
     V_segment       9..226
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <182..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66980.1"
                     /translation="DYHCAAGYGSGSSWQWVF"
     J_segment       227..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           63 a           89 c           94 g           55 t
ORIGIN      
        1 acatggggaa ttggggaatg tatacgccta ctggcaccag cagaagccag gccaggcccc
       61 tgtattggtc atctacaaag ataagaaccg gccctcaggg atccctgagc gattctctgg
      121 ctccagctca gggaacacgg ccaccctgac catcagtagg gtcgaggctg gggatgaggc
      181 cgactatcac tgtgctgcag gctatggcag tgggagcagc tggcagtggg tattcggcgg
      241 agggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01001243             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:20157:10242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001243
VERSION     KCWK01001243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20157:10242"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66981.1"
                     /translation="DYYCQVFDDSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          160 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aagtaaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacga tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001244             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:4965:12526
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001244
VERSION     KCWK01001244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4965:12526"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66982.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          107 a          137 c          120 g           99 t
ORIGIN      
        1 acatgggggt ggttctagga ggctgacctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgacc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatactcagt ggttccagca gaagccaggc cagggcccta gactggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacagtt accttgacca tcagcggggc ccagacagaa gatgaggctg actattactg
      361 tcaatcagca gacagaagtc ctaatcatgt gtttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001245             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:9428:12557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001245
VERSION     KCWK01001245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:9428:12557"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66983.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>459
                     /gene="IGLC"
BASE COUNT           93 a          142 c          132 g           92 t
ORIGIN      
        1 acatggggtg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgaa ttgactcagt
      121 caccctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa aactgtgcac tggtaccaac agaagccacc gcagggccct gtattggtca
      241 tctttgctga tagtagacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctccccg
//
LOCUS       KCWK01001246             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:15732:11682
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001246
VERSION     KCWK01001246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15732:11682"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66984.1"
                     /translation="DYYCCSYTTDSTYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          163 c          114 g          110 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtccgtc accatctcct gcactggaac
      181 catcagtgac gttggtggtc ataactctgt ctcctggtac caacaccacc cagacaaacc
      241 ccccaaagtc atgacttatg gtgtcagtaa tcgggcctca ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgttgtt catatacaac cgatagcact tacatcttcg gtagtgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001247             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:17962:10545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001247
VERSION     KCWK01001247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17962:10545"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..441
                     /note="immunoglobulin light chain variable region"
     V_region        111..441
     V_segment       111..404
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66985.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           83 a          155 c          127 g          114 t
ORIGIN      
        1 acatggggat tcctggctgt ggctcaggaa gcagagcctg gagcatctcc accatggcct
       61 gggctccact cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt
      121 tcactcagcc ccaatctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc
      181 gcagcagtgg cagcattggc aacagctatg tttactggtt ccagcagcgg ccgggcagcg
      241 tccccactat tgtgatttac aaagatgacc aaagaccctc tggggtccct gatcggttct
      301 ctggctccat cgatagttcc tccaactctg cctccctcac catctctgga ctgaagtctg
      361 gggacgaggc tgactattat tgtcagtctt ttgacagcag cagtgtctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001248             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:14189:18101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001248
VERSION     KCWK01001248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14189:18101"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66986.1"
                     /translation="DYYCSAWDSSLTGGFF"
     J_segment       407..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           97 a          155 c          123 g          107 t
ORIGIN      
        1 acatggggca gcttcagctg tggctagaga agacaggact caggacaatc tccagcatgg
       61 cctgcttccc tctcatcctc accgtcctca ctcactgtgc aggatcctgg gcccagtctg
      121 tgctgactca accaccctca gcgtctgggg cccccgggca gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaatt atgtatactg gtaccagcag ttctcaggga
      241 aggcccccaa actcctcatc cataataata atcagcgacc ctcaggggtc cctgatcgat
      301 tctctggctc caagtctggc acgtcagcct ccctggacat cagtgggctc cagtccgagg
      361 atgaggctga ttattactgc tcagcatggg atagcagtct gaccggtggc tttttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001249             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:19982:14879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001249
VERSION     KCWK01001249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19982:14879"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..264
                     /note="immunoglobulin light chain variable region"
     V_region        7..264
     V_segment       7..225
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66987.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       227..264
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>302
                     /gene="IGLC"
BASE COUNT           64 a           90 c           73 g           75 t
ORIGIN      
        1 acatgggcag ctccaacatt ggagattatt atgtgcagtg gtaccagcag cttccaggaa
       61 cggcccccaa actcctcatc tatgaaaata ataagcgacc ctcaggggtt tctgatcgat
      121 tctctggctc ccagtctggt acctcagcct ccctgaccat cactggactc cagtctgacg
      181 atgaggctga ttattactgt cagtcctatg atagcagcct gagtgttgtg ttattcggag
      241 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      301 cg
//
LOCUS       KCWK01001250             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:24673:13297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001250
VERSION     KCWK01001250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24673:13297"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66988.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           84 a          150 c          136 g           93 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcccatgatc tgactcagcc
      121 accctcggtg accgtgtccc caggacagac ggccaggatc acctgcgggg gacacaagat
      181 tcgaagtgaa gttgtgaact ggtaccagca gaagccagcg caggcccctg tattggtcat
      241 ctttgctgat accgaacggc ccgcagggat ccccgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tccgcggggt cgaggccggg gatgaggctg acttttactg
      361 tcaggtgtgg gacattcgta gtgatcgtcc gctattcggc ggagggaccc ggctcaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001251             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:21324:12066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001251
VERSION     KCWK01001251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21324:12066"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66989.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          154 c          119 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcggcat gggatgatag cctgagcggt tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001252             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:15901:8459
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001252
VERSION     KCWK01001252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15901:8459"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..296
                     /note="immunoglobulin light chain variable region"
     V_region        8..296
     V_segment       8..252
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66990.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       266..296
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>334
                     /gene="IGLC"
BASE COUNT           69 a          103 c           84 g           78 t
ORIGIN      
        1 acatggggga cagtcggtca ccatctcctg cactggaacc agcagtgatg ttgggtatta
       61 tcatgctgtg tcttggtacc agcatcatcc aggcaaagcc cccaaactca tgatttatga
      121 ggtcaataaa cggcccgcag gggtctctga tcgcttctct ggctccaagt ctggcaacac
      181 ggcctccctg accatctctg ggctccagac tgaggatgag gctgattatt actgcagctc
      241 atatgcaggc agcaacgctt tattcttcgg acgagggacc cgcctgaccg tcctaggtca
      301 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001253             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:5768:10418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001253
VERSION     KCWK01001253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:5768:10418"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66991.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          161 c          119 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagtatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctata ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001254             390 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:8657:1786
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001254
VERSION     KCWK01001254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 390)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 390)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..390
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8657:1786"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..352
                     /note="immunoglobulin light chain variable region"
     V_region        28..352
     V_segment       28..309
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <277..>324
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66992.1"
                     /translation="DYYCQVWDSTSDHYIF"
     J_segment       315..352
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        353..>390
                     /gene="IGLC"
BASE COUNT           80 a          124 c          109 g           77 t
ORIGIN      
        1 acatgggact gcacaggctc tgcgacctcc tatgagctga ctcagccacc ctcggtgtca
       61 gcggcctcag gacagacggc cagggtcacc tgtgggggag acaacattgg aactacgttt
      121 gtccactggt accagcagaa tccaccgcag gcccctgtgc aggtcatctt tgcggataac
      181 aaacggccct cagggatccc tgaacgattc tctggctcca actcagggaa caccgccacc
      241 ctgaccatca gcggggtcga ggccggggat gaggctgact attactgtca ggtgtgggac
      301 agtactagtg atcattacat cttcggtggt gggacccgcc tcaccgtcct aggtcagccc
      361 aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01001255             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:25013:4229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001255
VERSION     KCWK01001255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25013:4229"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..373
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66993.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       382..416
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           85 a          147 c          132 g           90 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacccttc tcctcctcgg
       61 cctcctcgct cactgcacag gctctgcgac ctcctatgag ctgactcagc caccctcggt
      121 gtcagcggcc tcaggacaga cggccaggat cccctgtggg ggagacaaca ttggaactaa
      181 atatgtgcac tggtaccagc agaagccagc gcaggcccct gtgttggtca tctatgctga
      241 taccagacgg ccctcaggga tccctgagcg attctctggc tccaactcag ggaacaccgc
      301 caccctgacc atcagcgggg tcgaggccgg gtatgaggct gactatttct gtcaggtgtg
      361 ggacgatagt agtgatcatc cggtattcgg cggagggacc cggctgaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001256             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:24297:11480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001256
VERSION     KCWK01001256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:24297:11480"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66994.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          163 c          110 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcaactgcac cttgaacagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccaac agaagccagg gagtcctccc cggtaccttc
      241 tgtactacta ctcagactca agtaaccacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttgctgat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccacatggc acagcagcgc ttcttacatc ttcggttctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001257             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:21089:3412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001257
VERSION     KCWK01001257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:21089:3412"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..389
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66995.1"
                     /translation="DYYCQVWDSDSKWIF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           96 a          143 c          133 g           91 t
ORIGIN      
        1 acatgggggc tgggtctcag gaggcagcat tgacggtgcc tcagccatgg cctggaccct
       61 tctcctcctc ggcctcctcg cttactgcac aggtactgcg acctcctatg aactgactca
      121 gccaccctca gtgtcagcgg cctcaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaact aaaaatgtgc actggtacca gcagaagcca gcgcagggcc ctgtattggt
      241 catgtttgct gataccagac ggccctcagg gatccctgac cgattctctg gctccaactc
      301 agggaacacc gccaccctga ccatcagcag ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagtg atagtaaatg gatattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001258             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:12906:17281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001258
VERSION     KCWK01001258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12906:17281"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66996.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       413..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          157 c          131 g          106 t
ORIGIN      
        1 acatgggggg gcagcttcag ctgtgggtac agaaggcagg actcaggaca atctccagca
       61 tggcctggtt ccctctcctc ctcaccctcc tcactcactg tgcagggtcc tgggcccagt
      121 ctgtgctgac tcagcctccc tcagcgtctg aggccgccag gaagagtgtc accatctcct
      181 gttctggaag cagctccaac atcggaagta atagtgtatc ctggtaccag cagctcccag
      241 aaacggctcc caaactcctc atcttttata atgatcggcg agcctcaggt gtctctgacc
      301 gattctctgg ctccaagtct ggcacgtcag cctccctggc catcagtggg ctccagaccg
      361 aggatgaggc tgattattac tgcgcagcat gggatgatag cctgagcggt ccggtattcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001259             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:21574:17985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001259
VERSION     KCWK01001259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21574:17985"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66997.1"
                     /translation="DYYCQSYDRSLSAVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           91 a          149 c          130 g          110 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg agattattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccagac tcctcattta tgaaaataat aagcgacgct cagggacttc tgatcgattc
      301 tctggctccc agtctggtac ctcagcctcg ctgaccatca gtggactcca gtctgaggat
      361 gaggctgact attactgtca gtcttatgac agaagcttga gtgctgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001260             517 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:10407:4822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001260
VERSION     KCWK01001260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 517)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10407:4822"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    149..479
                     /note="immunoglobulin light chain variable region"
     V_region        149..479
     V_segment       149..442
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <404..>451
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66998.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       445..479
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        480..>517
                     /gene="IGLC"
BASE COUNT          101 a          157 c          142 g          117 t
ORIGIN      
        1 acatggggag agtatgaaga cagggagagt ttatggggaa gctcagcttc agctgcgggt
       61 acagaaggca ggactcagga taatctccag catggcctgg ttccctctcg tactcaccct
      121 cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagccac cctcagcgtc
      181 tggggctccc gggcagagtg tcaccatctc ttgttctgga agcatctcca gcattggaag
      241 tagtgatgta tgttggtacc agcaactccc aggaacggcc cccaaactcc tcatcaatta
      301 tagtgatcag cgactctcag gggtccctga ccgattctct ggctctaagt ctggcacctc
      361 agcctccctg gccatcactg gtctccgatc tgaggatgag gctgattatt actgtgcagc
      421 ctgggatagc agcctgagca gtccggtatt cggcggaggg acccggctga ccgtcctagg
      481 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001261             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:18103:4179
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001261
VERSION     KCWK01001261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18103:4179"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV66999.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       402..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          151 c          121 g          114 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggttcaggct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat aacgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 ccaaactcat aatttttgac gtcattaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcgacacg gcctccctga ccatctctgg gctccgggct gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gaaataattt tttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001262             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:19197:11812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001262
VERSION     KCWK01001262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19197:11812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67000.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       411..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          153 c          126 g          114 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac gatctcctgc
      181 agtgggagca actccaacat tggatattat tatgtgcagt ggtaccagca gcttccagga
      241 acggccccca aactcctcat ctatgaaaat aataagcgac cctctggggt ttctgatcga
      301 ttctctggct cccagtctgg tacctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccactcctat gacagcagtt tgagtggtgt cttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001263             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15135:18060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001263
VERSION     KCWK01001263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15135:18060"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67001.1"
                     /translation="DYYCQVWGMTRDHPVF"
     J_segment       390..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           87 a          143 c          139 g           93 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gactctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggagag acggccagga tcacctgtgg gggagaccac
      181 attggaagtg aggttgtgaa ctggtaccaa cagaagccac cgcaggcccc tgtggtggtc
      241 tatcctaata gcgaacggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacacggcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg gcatgactag ggatcatccg gtattcggcg gagggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001264             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:10551:13439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001264
VERSION     KCWK01001264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10551:13439"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67002.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          152 c          122 g          112 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgtcccctcg gtcactctct tcccg
//
LOCUS       KCWK01001265             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:18854:13881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001265
VERSION     KCWK01001265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18854:13881"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..250
                     /note="immunoglobulin light chain variable region"
     V_region        7..250
     V_segment       7..212
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <175..>222
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67003.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       214..250
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        251..>288
                     /gene="IGLC"
BASE COUNT           61 a           89 c           80 g           58 t
ORIGIN      
        1 acatggggaa gtcaaagtgt gcactggtac cagcacaagc caccgcaggc ccctgttctg
       61 gtcatctttt attataccga acggccctca ggaatccctg agcgaatctc tggctccaaa
      121 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      181 tactgtcagg tgtgggacac aagtcttgat cacggcttat tcggaggagg gacccggctg
      241 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001266             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:4481:7460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001266
VERSION     KCWK01001266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:4481:7460"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..275
                     /note="immunoglobulin light chain variable region"
     V_region        79..275
     V_segment       79..238
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <200..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67004.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       239..275
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>313
                     /gene="IGLC"
BASE COUNT           60 a           96 c           84 g           73 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca cactcctcat ctattatgat gatcaacgag cctcaggtgt
      121 ctctgaccga ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct
      181 ccagaccgag gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta
      241 catcttcggt gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt
      301 cactctgttc ccg
//
LOCUS       KCWK01001267             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:25019:13646
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001267
VERSION     KCWK01001267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:25019:13646"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..407
                     /note="immunoglobulin light chain variable region"
     V_region        87..407
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67005.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       372..407
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>446
                     /gene="IGLC"
BASE COUNT           93 a          141 c          116 g           96 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aagatcacct gctctggaga tgcactgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcgat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgacaatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gcagtggtta tggcttattc ggaggaggga cccggctgac cgtcctacgt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001268             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:14690:3473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001268
VERSION     KCWK01001268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14690:3473"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..400
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67006.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       409..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           90 a          156 c          123 g          108 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc ggacagaggg tcaccatctc ctgcattagc
      181 agcagctcca acatcggggc ggcttattat gtatcctggt accgacagtt cccaggaaca
      241 gcccccaaac tcctcatctt tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggtcc ctcagcctcc ctgaccatca ctggactcca atctgaggat
      361 gaggctgatt attactgttt agcatgggat accagcctga attggatctt cggcggcggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001269             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:9636:6022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001269
VERSION     KCWK01001269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9636:6022"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67007.1"
                     /translation="DYYCAAWDDGLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          153 c          114 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcaacgtctg aggccgccag gaagagtgtc accatctcct gttctggaag caactccaac
      181 atcggaaatt ataatgtgtc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata atgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatgg cctgagcggt tacatcttcg ctgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001270             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:12340:19478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001270
VERSION     KCWK01001270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12340:19478"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..411
                     /note="immunoglobulin light chain variable region"
     V_region        63..411
     V_segment       63..372
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67008.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       374..411
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          147 c          101 g          110 t
ORIGIN      
        1 acatgggggc ctggactcct ctcctcctcc tgctcctctc tcactgcaca ggttccctct
       61 cgcagcctgt gctgactcag ccaacctccc tctcagcatc tcctggagca tcagccagac
      121 tcacctgcac cttgaacagt ggcatcagtg ttggtaatta caggatattc tggtaccacc
      181 agaagccagg gagtcctccc cggtatcttc tgaactacca cacagactca gatattcacc
      241 aggactctgg agtccccagc cgcttctctg ggtccaaaga tgcttcggcc aatgcaggga
      301 ttttactcat ctctggactc cagtctgaag atgaggctga ctattactgt atgatttggc
      361 acaacaatgc ttattgggta ttcggcggag ggacccggct aaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001271             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:20727:12435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001271
VERSION     KCWK01001271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20727:12435"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67009.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          150 c          120 g          106 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag cagctccaac
      181 attggagatt attatgtgca gtggtaccag caccttccag gaacggcccc cagactcctc
      241 atctatgaaa ataataagcg accctcaggg gtttctgatc gattctctgg ctcccagtct
      301 ggaacctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgccagtcct atgacagcag tttgattgct gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001272             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:15304:14479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001272
VERSION     KCWK01001272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15304:14479"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..260
                     /note="immunoglobulin light chain variable region"
     V_region        4..260
     V_segment       4..224
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>232
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67010.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       228..260
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>298
                     /gene="IGLC"
BASE COUNT           67 a           86 c           86 g           59 t
ORIGIN      
        1 acatggggga gacaacattg gaactaaaac tgtgcactgg taccaacaga agccaccgca
       61 gggccctcta ttggtcatct ttgctgatag tagacggccc tcagggatcc ctgagcgatt
      121 ctctggctcc aactcaggga acaccgccac cctgaccatc agcagggtcg aggccgggga
      181 tgaggctgac tattactgtc aggtgtggga cagtagtagt aaatggatat tcggcggggg
      241 gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001273             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:13603:4814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001273
VERSION     KCWK01001273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13603:4814"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67011.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       409..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           88 a          153 c          130 g          113 t
ORIGIN      
        1 acatggggga gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctctccttc tcactctgct ggttcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagcatctgg ggcccccggg cagagggtca ccatctcctg
      181 ctctgggagc agctccaaca tcggggcggg tttttatgtt tcctggtacc agcagttccc
      241 aggaacagcc cccaaactcc tcatctttga aaataataag cgaccctcag gggtttctga
      301 ccgattctct ggctccaagt ctggttcctc agcctccctg accatcactg gactccaatc
      361 tgaggatgag gctgattatt attgttcatc atgggaaagc agcctgaatt gggtattcgg
      421 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01001274             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:26548:7125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001274
VERSION     KCWK01001274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:26548:7125"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..248
                     /note="immunoglobulin light chain variable region"
     V_region        8..248
     V_segment       8..212
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>220
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67012.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       216..248
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        249..>286
                     /gene="IGLC"
BASE COUNT           61 a           84 c           85 g           56 t
ORIGIN      
        1 acatggggga actaaaactg tgcactggta ccagcagaag ccaccgcagg gccctgtatt
       61 ggtcatcttt gctgacagta aacggccctc agggatccct gagcgattct ctggctccaa
      121 ctcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      181 ttactgtcag gtgtgggaca gtagtagtaa atggatattc ggcgggggga cccggctaac
      241 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001275             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:25324:3136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001275
VERSION     KCWK01001275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:25324:3136"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67013.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          158 c          122 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001276             331 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:25173:8765
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001276
VERSION     KCWK01001276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 331)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25173:8765"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..293
                     /note="immunoglobulin light chain variable region"
     V_region        4..293
     V_segment       4..257
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <221..>265
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67014.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       258..293
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        294..>331
                     /gene="IGLC"
BASE COUNT           63 a          103 c           89 g           76 t
ORIGIN      
        1 acatgggcag tcggtcacca tctcctgcac tggaaccagc agtgacattg gtggttatga
       61 tggcgtctcc tggtaccagc agcactcagg gacagccccc agactcctga tttatgatgt
      121 cactaagcgg ccctcagggg tctcggatcg cttctctggc tccaagtctg gcaacacggc
      181 ctccctcacc atctctgggc tccagactga ggacgaggct gattattatt gttgctcata
      241 taggagtgga aacacttggc tattcggcgg agggacccgg ctgaccgtcc taggtcagcc
      301 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001277             384 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:8604:9853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001277
VERSION     KCWK01001277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 384)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 384)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8604:9853"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    22..346
                     /note="immunoglobulin light chain variable region"
     V_region        22..346
     V_segment       22..309
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>318
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67015.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       310..346
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        347..>384
                     /gene="IGLC"
BASE COUNT           81 a          114 c          103 g           86 t
ORIGIN      
        1 acatgggcag gttccgtggt ttcctctgag ctgactcagg agcctgcatt gtctgtggcc
       61 ttgggacaaa cagtcaggat gacctgccaa ggagacagcc tcaaaaccta ttatgcaagc
      121 tggtaccagc agaagccagg ccaggtccct gtgctggtca tctatggtaa caactaccgg
      181 ccctcaggga tcccaggccg attctctgtc tcctggtcag gaaacacagg ttccttgacc
      241 atcactgcgg ctcaggtgga agatgaggct gactattact gtaagtcctg ggacagcagt
      301 ggtacccatt acatcttcgg tgctgggacc cggctcaccg tcctaggtca gcccaaggct
      361 tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001278             361 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:10514:19036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001278
VERSION     KCWK01001278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 361)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10514:19036"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..323
                     /note="immunoglobulin light chain variable region"
     V_region        8..323
     V_segment       8..286
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <248..>295
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67016.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       287..323
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        324..>361
                     /gene="IGLC"
BASE COUNT           68 a          117 c           94 g           82 t
ORIGIN      
        1 acatgggcag cctccctcag cgtctgaggc cgccgggaag agtgtctcca tctcctgttc
       61 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac
      121 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      181 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      241 tgaggctgat tattactgcg cagcatggga tgatagcctg agcggttaca tcttcggtgc
      301 tgggacccgg ctcgccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      361 g
//
LOCUS       KCWK01001279             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:22308:9313
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001279
VERSION     KCWK01001279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22308:9313"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67017.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          149 c          135 g           95 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaac taaatatgtg cactggtacc agcagaagcc agcgcaggcc cctgtgttgg
      241 tcatctatgc tgataccaga cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcaccg gggtcgaggc cgggtatgag gctgactatt
      361 tctgtcaggt ttgggacgat agtagtgatc atccggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgcccact cggtcactct cttcccg
//
LOCUS       KCWK01001280             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:15686:17452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001280
VERSION     KCWK01001280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15686:17452"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67018.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          148 c          132 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggcccctg tgctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcaccggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg cttcttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001281             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:8638:10773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001281
VERSION     KCWK01001281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8638:10773"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67019.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          155 c          117 g          112 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgactacca cgtacactgg tatcagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggcctgg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaat acagggattt tacacatctc tggtttccag tctgaggatg
      361 aggctgacta ttactgtgcc attggccacg gcagcggtga ttacatcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001282             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:16426:6017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001282
VERSION     KCWK01001282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16426:6017"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..391
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67020.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       392..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          152 c          121 g          105 t
ORIGIN      
        1 acatggggga cagaaggcag gactcaggac aatctccagc atggcctggt tccctctcgt
       61 cctcaccctc ctcactcact gtgcagggtc ctgggcccag tctgtgctga ctcagcctcc
      121 ctcagcgtct gaggccgcca ggaagagtgt ctccatctcc tgttctggaa gcagctccaa
      181 catcggaagt catagtgtct cctggtacca gcaagtccca ggaacagctc ccaaactcct
      241 catctattat agtgatcaac gagcctcagg tgtctctgac cgattctctg gctctcagtc
      301 tggcacgtca gcctccctgg ccatcagtgg gctccagacc gaggatgagg ctgattatta
      361 ctgcgcagca tgggatgata gcctgagggg ttacatcttc ggtgctggga cccggctcgc
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001283             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:4283:17239
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001283
VERSION     KCWK01001283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4283:17239"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67021.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          159 c          116 g          110 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ttgcctacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gcgctggagt ccccagccgc ttctctggat
      301 ccaataatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtcc ttacatcttc ggttctggga
      421 cccgtctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001284             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:7283:12194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001284
VERSION     KCWK01001284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7283:12194"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67022.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       413..448
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           92 a          163 c          125 g          106 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctcgt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cacagccgcc ctcagtgtct ggggccccag ggcagagggt caccatcccc
      181 tgcactggga gcagctccaa cattggaggt tattatatat cctggtacca gcagctccca
      241 ggaacggccc ccaaactcct cgtctatgac aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggttcctca gccaccctga ccatcactgg gctccagact
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtctgagtgc tcgggtattc
      421 ggcggaggga cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01001285             453 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:23984:15576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001285
VERSION     KCWK01001285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 453)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:23984:15576"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..415
                     /note="immunoglobulin light chain variable region"
     V_region        88..415
     V_segment       88..375
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67023.1"
                     /translation="DYYCDSWDTTGTHPVLF"
     J_segment       378..415
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>453
                     /gene="IGLC"
BASE COUNT           88 a          145 c          120 g          100 t
ORIGIN      
        1 acatggggag agctctgggg tgtctccacc atggcctgga ctcctctctg gctcaccctc
       61 ctcagtcttt gcacaggttc tgtggtttcc tctggcctga ctcaggaccc tgcagtgtct
      121 gtggccttgg gacagactgt caggatcacc tgccaaggag acagcctcag aaccagttat
      181 gcaagctggt accagcagaa gccaggccag gcccctgtcc tggtcgtcta tggtaacaac
      241 taccggccct cagggatccc agagcgattc tctggctcca actcaagaaa cacagcttcc
      301 ttgaccatca ctgggactca ggtggaagat gaggctgact attactgtga ctcctgggac
      361 accaccggta cccatcctgt gttattcgga ggagggaccc ggctgaccgt cctaggtcag
      421 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001286             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:23143:4365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001286
VERSION     KCWK01001286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:23143:4365"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67024.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          155 c          122 g          109 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaataa tgtgtcctgg taccagcacc tcccaggaac
      241 agctcccaaa ctcctcatct attataatga tcaacgaggc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatt agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcgtggga tgatagcctg agcagttaca tcttcgctgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01001287             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:5505:20147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001287
VERSION     KCWK01001287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5505:20147"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67025.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       401..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           97 a          148 c          117 g          114 t
ORIGIN      
        1 acatgggggc ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcatctcc tggagcatca gccagactca cctgcacctt gcgcagtggc atcagtgttg
      181 gtagttacag gatattctgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 actataacac agactcagat aagaaccagg gatctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcagggattt tactcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtatg atttggcaca acaatgctta tgtgttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001288             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:17711:3847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001288
VERSION     KCWK01001288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17711:3847"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67026.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       398..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           86 a          156 c          124 g          103 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcatctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagcattgac aacggctttg tgtactggta ccagcagcgg ccgggcagcg ctcccaccac
      241 tgtgatttac aaagataacc aaagaccctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaacgctg cctccctcac catctctgga ctgaaatctg aggacgaggc
      361 tgactattac tgtcagtctt atgacagcag cagtgtatta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001289             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:4825:16622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001289
VERSION     KCWK01001289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:4825:16622"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67027.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           91 a          157 c          128 g          108 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt ccagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aacagtgtcg ccatctcctg
      181 ttctggaggc agctccaaca tcggaagtca tagtgtatcc tggtaccagc agctcccagg
      241 aacagctccc aaactcctca tctattatga tgatcaacga gcctcaggtg tctctggccg
      301 attctctggc tccaggtctg gcacgtcagc ctccctggcc atcagtgggc tccagaccga
      361 ggatgaggct gattattact gcgcagcatg ggatgatagc ctgagaggtt acatcttcgg
      421 tgatgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01001290             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:11271:17001
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001290
VERSION     KCWK01001290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:11271:17001"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67028.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          147 c          130 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagataac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001291             505 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:23241:4929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001291
VERSION     KCWK01001291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 505)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23241:4929"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    146..467
                     /note="immunoglobulin light chain variable region"
     V_region        146..467
     V_segment       146..430
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <395..>439
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67029.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       431..467
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        468..>505
                     /gene="IGLC"
BASE COUNT          101 a          152 c          144 g          108 t
ORIGIN      
        1 acatgggggg gcctgggaag gaataagaga agcctaggga gcccagctgt gctgtgggct
       61 caggaggcag agctctgggt gtctcaccat ggcctggatt cctctcctac tccccatcct
      121 cactttctgc acaggctctg cagcctccta tgagctgaca cagccaccct cggtgtcagt
      181 gtccccagga cagccggcca ggatcacctg ctctggagat gtattgccaa aaaaatatgc
      241 ttattggttc cagcagaagc caggccagtc ccctgtattg gtcatctctg aggacaccga
      301 acggccctct gggatccctg agagattctc tggctccagc tcagggacag tggccacctt
      361 gactatcagt ggggcccagg tggaggatga agctgactac tactgttact cagcagacag
      421 tagtggtcat ggcttcttcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc
      481 tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001292             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:15785:13744
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001292
VERSION     KCWK01001292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15785:13744"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67030.1"
                     /translation="DYYCAAWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          158 c          123 g          109 t
ORIGIN      
        1 acatgggggc agcctcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtatcct ggtatcaaca actcccagaa
      241 acggctccca aactcctcat gtattatagt catcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacttcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgaccggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001293             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:13525:19059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001293
VERSION     KCWK01001293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13525:19059"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67031.1"
                     /translation="DYYCAAWDNSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          157 c          122 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcagcgag actcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gataatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001294             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:22178:3791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001294
VERSION     KCWK01001294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22178:3791"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67032.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          159 c          125 g          111 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtctcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcag ctcccaggca
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc tcagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcttggg atgatagcct gagcggttac atcttcggtg
      421 ctgggacccg gctcgccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01001295             451 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:10938:7201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001295
VERSION     KCWK01001295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 451)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10938:7201"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..413
                     /note="immunoglobulin light chain variable region"
     V_region        92..413
     V_segment       92..377
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67033.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       381..413
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>451
                     /gene="IGLC"
BASE COUNT           92 a          140 c          129 g           90 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacccttc tcctcctcgg
       61 cctcctcgct tactgcacag ggtctgcgac ctcctatgaa ctgactcagt caccctcagt
      121 gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca ttggaactaa
      181 aactgtgcac tggtaccagc agaagccacc gcagggccct gtattggtca tctttgctga
      241 tagtaaacgg ccctcaggga tccctgagcg attctctggc tccaactcag ggaacaccgc
      301 caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg
      361 ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc taggtcagcc
      421 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001296             391 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:16338:10330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001296
VERSION     KCWK01001296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 391)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16338:10330"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..353
                     /note="immunoglobulin light chain variable region"
     V_region        23..353
     V_segment       23..316
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <278..>325
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67034.1"
                     /translation="DYYCQSYDVSLSAPLF"
     J_segment       319..353
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        354..>391
                     /gene="IGLC"
BASE COUNT           72 a          124 c          104 g           91 t
ORIGIN      
        1 acatggggca gggtcctggg cccagtctgt gctgacacag ccgccctctg tgtctggggc
       61 cccagggcag agggtcacca tctcctgcgc tgggagcagc tccaacattg gaggttatta
      121 tgtattctgg taccagcagg tcccaggaat ggcccccaaa ctcctcattt atgacaataa
      181 taaacgaccc tcaggggttt ctgaccgatt ctctggctcc aagtctggtt cctcagcctc
      241 cctgaccatc actgggctcc agactgagga tgaggctgat tattactgcc agtcctatga
      301 cgtctccctg agtgctccgt tattcggagg agggacccgg ctgaccgtcc taggtcagcc
      361 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001297             330 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18549:19752
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001297
VERSION     KCWK01001297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 330)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 330)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..330
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18549:19752"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..292
                     /note="immunoglobulin light chain variable region"
     V_region        8..292
     V_segment       8..255
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>264
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67035.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       258..292
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        293..>330
                     /gene="IGLC"
BASE COUNT           71 a           91 c          101 g           67 t
ORIGIN      
        1 acatgggcag gacagacggc caggatcacc tgtgggggag acaacattgg aagtaatagt
       61 gtgcattggt accagcagaa gccaccgcgg gcccctgtat tggtcatctc tgttgatagc
      121 gaacggccct cagggatccc tgagcgattc tctggttcca gatcagggaa caccgccacc
      181 ctgaccatca gcggggtcga ggccggggat gaggctgact attactgtca ggtgtgggat
      241 aatatttata aatacgcggt attcggcgga gggacccggc tgaccgtcct aggtcagccc
      301 aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001298             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:14619:19715
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001298
VERSION     KCWK01001298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14619:19715"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..422
                     /note="immunoglobulin light chain variable region"
     V_region        106..422
     V_segment       106..392
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67036.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       393..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>462
                     /gene="IGLC"
BASE COUNT           90 a          142 c          129 g          101 t
ORIGIN      
        1 acatggggag ctgtgggctc agaagcagag ctctggggtg tctccaccat ggcctggact
       61 cctctctggc tcaccctcct cagtctttgc acaggttcta tggtttcttc tgagctgact
      121 caggaccctg cagtgtctgt ggccttggga cagacagtca ggattacctg ccaaggagac
      181 agcctcagaa gctcttatgc aagctggtac caacagaggc caggccaggc ccctgtgctg
      241 gtcgtctatg gtaacaacta ccggccctca gggatcccag agcgattctc tggctcctac
      301 tcacgaaaca cagcttcctt gaccatctct ggggctcagg tggaagatga ggctgactat
      361 tactgtgact cctgggacag cagcggaacc caattcggag gagggacccg gctgaccgtc
      421 ctgggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001299             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:11995:8945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001299
VERSION     KCWK01001299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11995:8945"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67037.1"
                     /translation="YYYCSSYAGSHTYIF"
     J_segment       399..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           78 a          164 c          120 g          110 t
ORIGIN      
        1 acatgggggg ggtctcaggg ggcagcgctc tcaggacgtc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac agggtcctgg gctcaggctg ccctgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggttccag cagcaccccg gcaaagcccc
      241 caaactcatg atttatgatg tcactcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaaatct ggctacacgg cctccctgac catctctggg ctccaggctg cggatgaggc
      361 ttattattac tgcagctcat atgcgggcag ccacacttac atcttcggta ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01001300             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:21782:9033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001300
VERSION     KCWK01001300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21782:9033"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    72..402
                     /note="immunoglobulin light chain variable region"
     V_region        72..402
     V_segment       72..358
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <330..>374
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67038.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       372..402
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        403..>440
                     /gene="IGLC"
BASE COUNT           83 a          144 c          109 g          104 t
ORIGIN      
        1 acatgggctc caccatggtc tgggctctgc tcctcctcac cctcctcact cagggcacag
       61 gatcctgggc tcaggctgcc ccgactcaga ctccctctgt gtccgggtct cctggacagt
      121 cggtcaccat ctcctgcact ggaaccagca gtgatattgg gtattatcat gctgtgtctt
      181 ggtaccagca tcatccaggc aaagccccca aactcatgat ttatgaggtc aataaacggc
      241 ccgcaggggt ctctgatcgc ttctctggct ccaagtctgg caacacggcc tccctgacca
      301 tctctgggct ccagactgag gatgaggctg attattactg tagctcatat gcaggcagca
      361 acagtttatt cttcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      421 cctcggtcac tctcttcccg
//
LOCUS       KCWK01001301             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:12231:2140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001301
VERSION     KCWK01001301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12231:2140"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67039.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>437
                     /gene="IGLC"
BASE COUNT           89 a          133 c          126 g           89 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctcttcgacc tcctatgaac tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa actgtgcact ggtaccagca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgac agtaaacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcactct cttcccg
//
LOCUS       KCWK01001302             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18340:20506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001302
VERSION     KCWK01001302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18340:20506"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67040.1"
                     /translation="AYYCQVWDSDTDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          151 c          129 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga cctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaagccag cgcaggcccc tatgcaggtc
      241 atctatgctg atagcaaacg gccctcaggg atccctgaga gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctattac
      361 tgtcaggtgt gggacagtga tactgatcat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001303             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:20848:6510
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001303
VERSION     KCWK01001303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20848:6510"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..446
                     /note="immunoglobulin light chain variable region"
     V_region        101..446
     V_segment       101..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67041.1"
                     /translation="DYYCQVYDSNAVLF"
     J_segment       413..446
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           91 a          165 c          120 g          108 t
ORIGIN      
        1 acatgggggg gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtac tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagcagtga
      181 cctcagtgtt ggcagtaaaa acatgtactg gtaccagcag aagccaggga gcgctcccag
      241 gttattcctc tactactact ccgactcaga caaccaactg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt attactgcca ggtgtatgac agtaatgctg ttttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01001304             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:9021:6556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001304
VERSION     KCWK01001304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:9021:6556"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67042.1"
                     /translation="DYSCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           81 a          157 c          128 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg ggctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattct tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001305             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:6824:7141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001305
VERSION     KCWK01001305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6824:7141"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67043.1"
                     /translation="DYHCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          163 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgtt ctacttctcc gactcagaca accagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaattaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001306             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:13362:14067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001306
VERSION     KCWK01001306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13362:14067"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67044.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          159 c          119 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001307             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:14433:2686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001307
VERSION     KCWK01001307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14433:2686"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..433
                     /note="immunoglobulin light chain variable region"
     V_region        104..433
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67045.1"
                     /translation="DYYCSSFAGRNNLFF"
     J_segment       404..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>472
                     /gene="IGLC"
BASE COUNT           87 a          155 c          118 g          112 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtaatctt gggtatttta atgctgtgtc ttggtaccaa caacatccag gcaaagcccc
      241 caaactcatg atttacgacg tcactaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagttcat ttgccggcag gaacaattta tttttcggag gagggacccg
      421 gctgaccgtc ctaagtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001308             274 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:8194:6236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001308
VERSION     KCWK01001308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 274)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 274)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8194:6236"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..236
                     /note="immunoglobulin light chain variable region"
     V_region        7..236
     V_segment       7..199
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <167..>208
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67046.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       203..236
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        237..>274
                     /gene="IGLC"
BASE COUNT           55 a           82 c           74 g           63 t
ORIGIN      
        1 acatgggcag aagccaggga gcgctcccaa gttattcctg tactactact ccgactcaga
       61 catgcagctg ggacctgggg tccccaatcg agtctctggc tccaaggaga cctcaagtca
      121 tacagcgttt ttgctcatct ctgggctcca gcctgaggac gaggccgatt attactgtca
      181 ggtgtatgac agtagtgctg tattattcgg aggagggacc cggctgaccg tcctaggtca
      241 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001309             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:19595:23224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001309
VERSION     KCWK01001309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19595:23224"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..440
                     /note="immunoglobulin light chain variable region"
     V_region        114..440
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67047.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>482
                     /gene="IGLC"
BASE COUNT           87 a          157 c          127 g          111 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtctcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaccgagc ctcaggtgtc tctgaccgat
      301 tctctggctc tcagtctggc acgtcagcct ccctggccat cagtgggctc caggccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagtct gagcggttac atcttcggtg
      421 ctgggacccg gctcgccgtc gtaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01001310             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:23364:8259
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001310
VERSION     KCWK01001310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23364:8259"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67048.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          141 c          134 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaggccaccg caggcccctg tactggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001311             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:20153:6973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001311
VERSION     KCWK01001311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20153:6973"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67049.1"
                     /translation="DYYCCSYAGSDTFVLF"
     J_segment       404..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           85 a          162 c          124 g          107 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caacaacatc cagccacagc
      241 ccccaaactc gtgatttatg aggtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct ggcctccagc ctgaggacga
      361 ggctgattat tactgctgct catatgcagg cagcgacact ttcgtgttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001312             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:4305:5985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001312
VERSION     KCWK01001312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4305:5985"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67050.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       404..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           87 a          159 c          124 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacagaatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggcggtt ataactatgt ctcctggtac caacagcatc cagacacagc
      241 ccccaaactc atgatttatg aggtcactaa gcgaccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgctgct cacatgcagg cagtgatatt ttcgtgttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001313             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:19903:4133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001313
VERSION     KCWK01001313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19903:4133"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67051.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       415..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          164 c          119 g          112 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catttactgg taccagcaga agccagggcg cgctcccagg
      241 tttttcctgt actacaactc cgactcagac aagcagctgg gacctggggt ccccaatcgc
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcac gtatatgaca gtagtactaa tgtattattc
      421 ggaggaggga cccgtctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01001314             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:20288:15048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001314
VERSION     KCWK01001314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20288:15048"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67052.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          154 c          127 g          113 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac catctcctgc
      181 actgggagca gctccaacat tggaggttat tatgtgcagt ggtaccagca gcttccagga
      241 acggccccca aactcctcat ctatgaaaat gataaacgac cctcaggggt ttctgatcga
      301 ttctctggct cccagtctga ttcctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagcagct tgagtgttgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001315             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:25636:9015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001315
VERSION     KCWK01001315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:25636:9015"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67053.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       397..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           82 a          152 c          125 g          110 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcatctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccaatctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagcattggc aacagctatg tttactggtt ccagcagcgg ccgggcagcg tccccactat
      241 tgtgatttac aaagatgacc aaagaccctc tggggtccct gatcggttct ctggctccat
      301 cgatagttcc tccaactctg cctccctcac catctctgga ctgaagtctg gggacgaggc
      361 tgactattat tgtcagtctt ttgacagcag cagtgtctta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001316             318 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:16625:15604
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001316
VERSION     KCWK01001316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 318)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16625:15604"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..280
                     /note="immunoglobulin light chain variable region"
     V_region        8..280
     V_segment       8..244
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>252
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67054.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       245..280
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        281..>318
                     /gene="IGLC"
BASE COUNT           75 a           90 c           92 g           61 t
ORIGIN      
        1 acatgggcgg ccaggatcac ctgtggcgga gacaacattg gaattaaaaa tgtccactgg
       61 taccagcaga agccagcaca ggcccctgtg gtagtcatct atgctgataa caaacggccc
      121 tcagggatcc ctgagcgact ctctggctcc aactcaggga atattgccac cctgaccatc
      181 agcagggtcg aggccgggga tgaggcagac tattactgtc aggtgtggga cagtagtagt
      241 aaatgggtat tcggcggagg gacccggcta accgtcctag gtcagcccaa ggctgccccc
      301 tcggtcactc tcttcccg
//
LOCUS       KCWK01001317             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:17502:3722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001317
VERSION     KCWK01001317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17502:3722"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67055.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       216..251
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           58 a           82 c           89 g           60 t
ORIGIN      
        1 acatggggga ggtgaagttg tgaattggta ccagcagaag ccaccgcagg cccctgtgtt
       61 ggtcatctat gctgatagcg agcggccctc agggatcccg gagcgattct ctggctccaa
      121 atcagggaac acggccaccc tgaccatcag cggggtcgag gccggagatg aggctgacta
      181 ttactgtcag gtgtgggacc ttaatagtca tcatctgtta ttcggaggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001318             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:21983:6220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001318
VERSION     KCWK01001318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21983:6220"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67056.1"
                     /translation="DYYCQSGDSSGNHWVF"
     J_segment       392..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          107 a          133 c          128 g           98 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct gtggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagaaggca ggccaggccc ctctgctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag agattctcta gctccagtcc
      301 agggccaaca tttaccttga ccaacagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca ggagacagca gtggtaatca ttgggtattc ggcggaggga cccggctaag
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001319             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:5626:18663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001319
VERSION     KCWK01001319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:5626:18663"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..454
                     /note="immunoglobulin light chain variable region"
     V_region        115..454
     V_segment       115..417
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67057.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       418..454
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           95 a          159 c          129 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca ggtcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg caagtctggc acgtcagcct ccctggccat cactgggctc
      361 cagaccgagg atgaggctga ttattactgc gcagcatggg atgatagcct gagcggttac
      421 atcttcgggg ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCWK01001320             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:27590:19024
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001320
VERSION     KCWK01001320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:27590:19024"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67058.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           98 a          139 c          131 g           92 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgagc tgactcaggc
      121 actttcagtg tcagcggcct caggacagac ggccaggatc acctgtggcg gagacaacat
      181 tggaattaaa aatgtacact ggtaccagca gaagccacca caggcccctg tggtggtcat
      241 ctatgctgat aacaaacggc cctcagggat ccctgagcga ctctctggct ccaactcagg
      301 gaatattgcc accctgacca tcagcagggt cgaggccggg gatgaggcag actattactg
      361 tcaggtgtgg gacagtagta gtaaatgggt attcggcgga gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001321             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:15219:6162
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001321
VERSION     KCWK01001321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15219:6162"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67059.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          161 c          113 g          109 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatc
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggggggggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001322             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:13601:15251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001322
VERSION     KCWK01001322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13601:15251"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..441
                     /note="immunoglobulin light chain variable region"
     V_region        94..441
     V_segment       94..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67060.1"
                     /translation="DYYCAIGHSSGNYIF"
     J_segment       408..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          157 c          119 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctat gctgactcag ccggcctcct
      121 tctcagcatc tcctggagct tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtttcttc
      241 tgagatacaa gtcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaagga tgcttcagcg agcacaggaa ttttacgcat ctctggcctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg taattatatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001323             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:12584:12142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001323
VERSION     KCWK01001323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12584:12142"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..433
                     /note="immunoglobulin light chain variable region"
     V_region        88..433
     V_segment       88..396
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67061.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           93 a          160 c          108 g          110 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gaacatcagc cagactcagc tgcaccttga gcagtggcaa tgttggtagt
      181 tacagcatat tctggtacca gcagaagcca gggagtcctc cccggtacct tctttactac
      241 tactcagact caagtaacca ccaggactct ggagtcccca gccgcttctc tggatcgaaa
      301 gatgcttcag ccaatgcagg gcttttactg atctctgggc tccagtctga agatgaggct
      361 gactattact gtgccacatg gcacagcagc gcttcttaca tcttcggtcc tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01001324             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:12236:10416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001324
VERSION     KCWK01001324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12236:10416"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67062.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       402..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           91 a          158 c          113 g          112 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagt cagactcagc tgcaccttga gcagtggcat caatgttggt
      181 tcttacacca tattctggta ccagcagaag ccagggagtc ctccccggtt ccttctgtac
      241 tactactcag actcaaataa tcaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagccaatgc agggctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccat gtggcacagc agcgcttatg ccttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001325             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:14706:15954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001325
VERSION     KCWK01001325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14706:15954"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67063.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       406..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           88 a          154 c          126 g          113 t
ORIGIN      
        1 atggggtctg cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag tgtctggggc gcccgggcag agggtcaccc tctcctgcac
      181 tgggagcagc tccaacattg gagattatta tgtgcagtgg taccagcagc ttccaggaac
      241 ggcccccaaa ctcctcatct atgaaaataa taagcgaccc tcaggggttt ctgatcgatt
      301 ctctggctcc cagtctggta cctcagcctc cctgaccatc actggactcc agtctgacga
      361 tgaggctgat tattactgtc agtcctatga tagcagcctg agtgttgtgt tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01001326             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:11297:10433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001326
VERSION     KCWK01001326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11297:10433"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67064.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           95 a          156 c          127 g          106 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagactccct cagcgtctga ggccgccagg aagagtgtca ccatctcctg
      181 ttctggaagc agctccaaca tcggaagaaa tagtgtatcc tggtaccagc agctcccagg
      241 aacagctccc aaactcctca tctattatag tgatcaacga gcctcaggtg tctctgaccg
      301 attctctggc tccaagtctg gcacgtcagc ctccctggcc atcagcgggc tccaggccga
      361 ggatgaggct gattattact gcgcagcatg ggatgatagc ctgagcggtt acatcttcgg
      421 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01001327             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:20114:8800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001327
VERSION     KCWK01001327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20114:8800"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..417
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67065.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       418..454
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           97 a          158 c          128 g          109 t
ORIGIN      
        1 acatgggggg gtgaagcgca gcttcagctg tgggtacaga aggcaggact caggacaatc
       61 tccagcatgg cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg
      121 gcccagtctg tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc
      181 atctcctgtt ctggaagcag ctccaacatc ggaagtaata atgtgtcctg gtaccagcac
      241 ctcccaggaa cagctcccaa actcctcatc tattataatg atcaacgagg ctcaggtgtc
      301 tctgaccgat tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc
      361 cagaccgagg atgaggctga ttattactgc gcagcgtggg atgatagcct gagcagttac
      421 atcttcgctg ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCWK01001328             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:10163:5423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001328
VERSION     KCWK01001328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10163:5423"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..398
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67066.1"
                     /translation="DYYCSSYGGSNTLFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           90 a          152 c          120 g          109 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 actccctctg tgtccgggtc tcctggacag tcggtcacca tcacctgcac tggaaccagc
      181 agtgatattg ggtattatca tgctgtgtct tggtaccagc atcatccagg caaagccccc
      241 aaactcatga tttatgaggt caataaacgg cccgcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 gattattact gcagctcata tggaggcagc aatactttat tcttcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001329             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12979:16327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001329
VERSION     KCWK01001329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12979:16327"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67067.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          160 c          124 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtggtg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaata cagcgttttt ggtcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001330             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:4888:11080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001330
VERSION     KCWK01001330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4888:11080"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67068.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          158 c          118 g          110 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcacc tccaacatcg gaagcaataa tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctctttt attataatga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctcttgctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg catcatggga tgataccctg agcggctaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01001331             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:13808:9473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001331
VERSION     KCWK01001331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13808:9473"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    67..397
                     /note="immunoglobulin light chain variable region"
     V_region        67..397
     V_segment       67..360
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <322..>369
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67069.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       363..397
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        398..>435
                     /gene="IGLC"
BASE COUNT           76 a          143 c          114 g          102 t
ORIGIN      
        1 acatggggca tggcctggtt ccctctcgta ctcaccctcc tcactcactg tgcagggtcc
       61 tgggcccagt ctgtgctgac tcagccaccc tcagcgtctg gggctcccgg gcagagtgtc
      121 accatctctt gttctggaag catctccagc attggaagta gtgatgtatg ttggtaccag
      181 caactcccag gaacggcccc caaactcctc atcaattata gtgatcagcg actctcaggg
      241 gtccctgacc gattctctgg ctctaagtct ggcacctcag cctccctggc catcactggt
      301 ctccgatctg aggatgaggc tgattattac tgtgcagcct gggatagcag cctgagcagt
      361 ccggtattcg gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      421 gtcactctct tcccg
//
LOCUS       KCWK01001332             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:19561:14165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001332
VERSION     KCWK01001332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19561:14165"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67070.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       391..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          138 c          138 g          100 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagg
      121 caccctcgat ttcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttttgaac tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tgtatgctga tagcgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacatgaat agtcatcatc tgttattcgg aggggggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001333             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:16477:19535
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001333
VERSION     KCWK01001333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:16477:19535"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..399
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67071.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       403..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           86 a          157 c          126 g          105 t
ORIGIN      
        1 acatgggggg gctgtggctc aggaagcaga gcctggagca tctccaccat ggcctgggct
       61 ccactcctcc tcaccctcct cgctcactgc acagggtctt gggctgaggt tgtgttcact
      121 cagccccatt ctgtgtcggg gtctccgggg cagacggtca ccatctcctg cacccgcagc
      181 agtggcagca ttgacaacgg ctttgtgtac tggtaccagc agcggccggg cagcgctccc
      241 accactgtga tttacaaaga taaccaaaga ccctctgggg tccctgatcg gttctctggc
      301 tccatcgaca gctcctccaa ctctgcctcc ctcaccatct ctggactgaa atctgaggac
      361 gaggctgact attactgtca gtcttatgac agcagcagtg tattattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001334             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:4790:13244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001334
VERSION     KCWK01001334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:4790:13244"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..434
                     /note="immunoglobulin light chain variable region"
     V_region        88..434
     V_segment       88..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67072.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       400..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>474
                     /gene="IGLC"
BASE COUNT           90 a          162 c          109 g          113 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttta gcagtggcat caatgttggt
      181 agttacagca tattctggta ccagcagaag ccagggagtc ctccccggta ccttctctac
      241 tactactcag actcaagtaa acaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cggccaatgc aggcctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccat atggcacagc agcgcttctt acttcttcgg ttccgggacc
      421 cggctcaccg tcctgggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001335             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:5251:12311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001335
VERSION     KCWK01001335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:5251:12311"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..377
                     /note="immunoglobulin light chain variable region"
     V_region        88..377
     V_segment       88..341
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>350
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67073.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       342..377
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>416
                     /gene="IGLC"
BASE COUNT           87 a          123 c          114 g           92 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc catcctcact ttctgcacag tgtccccagg acagacggcc aagatcacct
      121 gctctggaga tgcactgcca aaaaaatttg cttattggtt ccagcagaag ccaggccagt
      181 cccctgtgtt gatcatcgat gaagacagta aacggccctc tgggatccct gagagaatct
      241 ctggctccag ttcagggaca gtggccacct tgactatcag tggggcccag gtggaggatg
      301 aagctgacta ctactgttac tcagcagaca gcagtggtta tggcttattc ggaggaggga
      361 cccggctgac cgtcctacgt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001336             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:11044:10159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001336
VERSION     KCWK01001336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:11044:10159"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67074.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          147 c          131 g           96 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gttctggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg aatcgctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaagt cttgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001337             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:18977:17312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001337
VERSION     KCWK01001337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18977:17312"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67075.1"
                     /translation="DYYCQVWDTSIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          143 c          129 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgagg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg cactggtcat
      241 cttttattat agcgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaatactgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagta ttgatcatgg cttattcgga agagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001338             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:22968:7353
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001338
VERSION     KCWK01001338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:22968:7353"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67076.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       403..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           95 a          162 c          111 g          109 t
ORIGIN      
        1 atggggactg tggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc aagcctatgc tgactcagcc ggcctccctc
      121 tcagcaactc ctggagcatc agccagtctc acatgcacct tcagcggtgg catcaatgtt
      181 gctgcctacc acatacactg gtaccagcag aagccaggga gtcccccccg gtatcttctg
      241 acttacaaat cagactcaga taagggccag ggctctggag tccccagccg cttctctgga
      301 tccaaaaatg cttcaacgaa cacaggcatt ttacacatct ctgggctcca gtctgaggat
      361 gaggctgact atttctgtgc cattggacac agcagcggtc cttacatctt cggtgctggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01001339             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:6806:3392
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001339
VERSION     KCWK01001339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6806:3392"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..266
                     /note="immunoglobulin light chain variable region"
     V_region        8..266
     V_segment       8..229
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67077.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       232..266
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           64 a           83 c           93 g           64 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaagtaa tagtgtgcat tggtaccagc agaagccacc
       61 gcgggcccct gtattggtca tctctgttga tagcgaacgg ccctcaggga tccctgagcg
      121 attctctggt tccagatcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggataatatt tataaatacg cggtattcgg
      241 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      301 cccg
//
LOCUS       KCWK01001340             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:19682:11506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001340
VERSION     KCWK01001340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19682:11506"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67078.1"
                     /translation="DYYCQVWDISSEHVLF"
     J_segment       392..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          140 c          135 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagc ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcggtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaggtgca gttgtgaatt ggtaccacca gaagccaccg caggcccctg tactggtcat
      241 ctatgctgat agcgatcggc cctcagggat ccctgagcga ttctctggct tcaaatcaga
      301 aaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattagta gtgaacatgt attattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001341             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:12724:16013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001341
VERSION     KCWK01001341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12724:16013"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..404
                     /note="immunoglobulin light chain variable region"
     V_region        88..404
     V_segment       88..374
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67079.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       375..404
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>444
                     /gene="IGLC"
BASE COUNT           87 a          139 c          120 g           98 t
ORIGIN      
        1 tcagaagcag agctctgggg tgtctccacc atggcctgga ctcctctctg gctcaccctc
       61 ctcagtcttt gcacaggttc tatggtttct tctgagctga ctcaggaccc tgcagtgtct
      121 gtggccttgg gacagacagt caggattacc tgccaaggag acagcctcag aagctcttat
      181 gcaagctggt accaacagag gccaggccag gcccctgtgc tggtcgtcta tggtaacaac
      241 taccggccct cagggatccc agagcgattc tctggctcct actcacgaaa cacagcttcc
      301 ttgaccatct ctggggctca ggtggaagat gaggctgact attactgtga ctcctgggac
      361 agcagcggaa cccaattcgg aggagggacc cggctgaccg tcctgggtca gcccaaggct
      421 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001342             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:17329:14890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001342
VERSION     KCWK01001342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17329:14890"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67080.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          161 c          113 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgctgctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttagtgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001343             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11731:17660
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001343
VERSION     KCWK01001343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11731:17660"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67081.1"
                     /translation="DYYCQVWDIYTEHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          139 c          140 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgagtcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggtcagga tcacctgtgg aggagacagc
      181 tttggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgagcg gccctcaggg atccctgagc gattttctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacattta tactgagcat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001344             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:25874:10154
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001344
VERSION     KCWK01001344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:25874:10154"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67082.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          160 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccaggctccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcaactggg acctggggtc cccaatcggg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcaga tgtatgacag tagtgatgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001345             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:10887:15434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001345
VERSION     KCWK01001345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10887:15434"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67083.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          164 c          109 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtactta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaagga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001346             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:8891:7247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001346
VERSION     KCWK01001346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:8891:7247"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..391
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67084.1"
                     /translation="DYYCQTWDTGIVSF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          156 c          122 g          102 t
ORIGIN      
        1 acatggggga gagccctgag gagtctgcac catggcctgg accccaatcc tcctcctcct
       61 cactctcctc cttcactgca cagggtctct ctcccagcct gtgctgactc agtcgccctc
      121 tgcctctgcc tccctgggag cctcggtcaa gctcacctgt actctgagca gtggacacag
      181 cagctacacc atcgcatggc atcagcacca gcaagggaag gcccctcggt atttgatgtg
      241 gcttaaaagt gatggcagcc acagcaaggg ggacgggatc cctgatcgct tctcaggctc
      301 cagttccggg gctgagcgct acctcaccat ctccaatttc cagtctgagg atgaggctga
      361 ttattactgt cagacctggg atactggcat tgtgtcattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001347             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:16678:4863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001347
VERSION     KCWK01001347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:16678:4863"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..398
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67085.1"
                     /translation="DYYCAAGYGSGSDWQWVF"
     J_segment       399..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           94 a          154 c          131 g           94 t
ORIGIN      
        1 acatggggga tcctggcttc agaagcagca tctgggacat gtcagccatg gcctggacgc
       61 ctctcctcct cagcctcctc gctcactgca caggctctgc ggcctcctat gacctgactc
      121 agccaccctc agtgtcggtg tccccaggac agacagccat catcacctgc tctggaaatg
      181 aattggggaa tgtatatgct tcctggtacc accagaagcc aggccaggcc cctgtattgg
      241 tcatctacaa agataccaac cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac ggccaccctg accatcagca gggtcgaggc tggggatgaa gccgactatt
      361 actgtgctgc aggctatggc agtgggagcg actggcagtg ggtattcggc ggggggaccc
      421 ggctaaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001348             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:12578:4328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001348
VERSION     KCWK01001348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12578:4328"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67086.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          157 c          128 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcagcact cagggacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tattgttgct catataggag tggaaacact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001349             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:9331:20623
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001349
VERSION     KCWK01001349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9331:20623"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..434
                     /note="immunoglobulin light chain variable region"
     V_region        110..434
     V_segment       110..391
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67087.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       400..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          152 c          137 g           96 t
ORIGIN      
        1 acatgggggc cctgtctggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggcc tcctcgctca ctgcacaggc tctgcgacct cctatgagct
      121 gactcagcca ccctcggtgt cagcggcctc aggacagacg gccaggatca cctgtggggg
      181 agacaacatt ggaactaaat atgtgcactg gtaccagcag aagccagcgc aggcccctgt
      241 gttggtcatc tatgctgata ccagacggcc ctcagggatc cctgagcgat tctctggctc
      301 caactcaggg aacaccgcca ccctgaccat cagcggtgtc gaggccgggt atgaggctga
      361 ctatttctgt caggtgtggg acgatagtag tgatcatccg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001350             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:16562:17286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001350
VERSION     KCWK01001350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16562:17286"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67088.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          151 c          136 g           92 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta agtatgtgca ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atctatgctg ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg ggtatgaggc tgactatttc
      361 tgtcaggtgt gggacgatag cagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001351             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:8554:10897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001351
VERSION     KCWK01001351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8554:10897"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..404
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67089.1"
                     /translation="DYYCAAWDDSLRSYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          156 c          124 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgaggagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001352             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:12581:20487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001352
VERSION     KCWK01001352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12581:20487"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67090.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          163 c          120 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaacc cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001353             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:19404:9846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001353
VERSION     KCWK01001353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:19404:9846"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..262
                     /note="immunoglobulin light chain variable region"
     V_region        5..262
     V_segment       5..225
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <187..>234
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67091.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       226..262
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        263..>300
                     /gene="IGLC"
BASE COUNT           64 a           91 c           83 g           62 t
ORIGIN      
        1 acatggggag acaacattgg aagtaagagt gtgcactggt accagcacaa gccaccgcag
       61 gcccctatcc tggtcatcta ttattatacc gaacggccct cggcgatccc tgagcgattc
      121 tctggctcca aatcagggaa caccgccacc ctgaccatca gcggggtcga ggccggggat
      181 gaggctgact attactgtca ggtgtgggac actactattg atcatggctt tttcggagga
      241 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001354             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:12342:18454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001354
VERSION     KCWK01001354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12342:18454"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..428
                     /note="immunoglobulin light chain variable region"
     V_region        107..428
     V_segment       107..392
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67092.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       396..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          143 c          133 g           97 t
ORIGIN      
        1 acatggggct gtctgggtct caggaggcag cattgacggt gcctcagcca tggcctggac
       61 ccttctcctc ctcggcctcc tcgcttactg cacaggctct gcgacctcct atgaattgac
      121 tcagtcaccc tcagtgtcag cggcctcagg acagccggcc aggatcacct gtgggggaga
      181 caacattgga actaaaactg tgcactggta ccaacagaag ccaccgcagg gccctgtatt
      241 ggtcatcttt gctgatagta gacggccctc agggatccct gagcgattct ctggctccaa
      301 ttcagggaac accgccaccc tgaccatcag cagggtcgag gccggggatg aggctgacta
      361 ttactgtcag gtgtgggaca gtagtagtaa atggatattc ggcgggggga cccggctaac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001355             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:19009:17912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001355
VERSION     KCWK01001355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19009:17912"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..391
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67093.1"
                     /translation="DYYCQTWDTDTVLF"
     J_segment       393..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>468
                     /gene="IGLC"
BASE COUNT           89 a          160 c          120 g           99 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgtctctg cctccctggg agcctcggtc aaactcacct gtactttgaa cagtgggcac
      181 agcagctaca ccatcgcatg gcatcagcag cagcaaggga aggccccccg gtacttgatg
      241 tggcttaaaa gtgaaggcag ccatagcaag ggggacggga tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatactgac actgtgttat tcggaggagg gacccggctg
      421 accgtcccag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001356             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:7280:5061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001356
VERSION     KCWK01001356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7280:5061"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67094.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          162 c          115 g          108 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctctgcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcagactca gataaggacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcctcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctactactgt gccattgggc acagcagcgg tgattacatc ttcgctgctg
      421 ggacccgcct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001357             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:20841:2715
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001357
VERSION     KCWK01001357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20841:2715"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67095.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          161 c          120 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcaga tgtatgacag tagtgatgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001358             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:16889:15325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001358
VERSION     KCWK01001358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16889:15325"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..408
                     /note="immunoglobulin light chain variable region"
     V_region        92..408
     V_segment       92..378
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67096.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       379..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>448
                     /gene="IGLC"
BASE COUNT           88 a          139 c          123 g           98 t
ORIGIN      
        1 acatggggaa gcagagctct ggggtgtctc caccatggcc tggactcctc tctggctcac
       61 cctcctcagt ctttgcacag gttctatggt ttcttctgag ctgactcagg accctgcagt
      121 gtctgtggcc ttgggacaga cagtcaggat tacctgccaa ggagacagcc tcagaagctc
      181 ttatgcaagc tggtaccaac agaggccagg ccaggcccct gtgctggtcg tctatggtaa
      241 caactaccgg ccctcaggga tcccagagcg attctctggc tcctactcac gaaacacagc
      301 ttccttgacc atctctgggg ctcaggtgga agatgaggct gactattact gtgactcctg
      361 ggacagcagc ggaacccaat tcggaggagg gacccggctg accgtcctgg gtcagcccaa
      421 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001359             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:13766:7829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001359
VERSION     KCWK01001359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13766:7829"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67097.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          161 c          109 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcttcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001360             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:17353:12313
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001360
VERSION     KCWK01001360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17353:12313"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..391
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67098.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          143 c          134 g           95 t
ORIGIN      
        1 acatgggggg tctgggtctc aggaggcagc attgacggtg cctcagccat ggcctggacc
       61 cttctcctcc tcggcctcct cgcttactgc acaggctctg cgacctccta tgaattgact
      121 cagtcaccct cagtgtcagc ggcctcagga cagccggcca ggatcacctg tgggggagac
      181 aacattggaa ctaaaactgt gcactggtac caacagaagc caccgcaggg ccctgtattg
      241 gtcatctttg ctgatagtag acggccctca gggatccctg agcgattctc tggctccaac
      301 tcagggaaca ccgccaccct gaccatcagc agggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtagtaaa tggatattcg gcggggggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001361             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:16086:8210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001361
VERSION     KCWK01001361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16086:8210"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..396
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67099.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           87 a          153 c          123 g          108 t
ORIGIN      
        1 acatgggggt aggtacagaa ggcaggactc aggacaatct ccagcatggc ctggttccct
       61 ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt gctgactcag
      121 cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc tggaagcagc
      181 tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac agctcccaaa
      241 ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt ctctggctct
      301 cagtctggca cgtcagcctc cctggccatc agtgggctcc aggccgagga tgaggctgat
      361 tattactgcg cagcatggga tgatagtctg agcggttaca tcttcggtgc tgggacccgg
      421 ctcgccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01001362             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18602:8499
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001362
VERSION     KCWK01001362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18602:8499"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67100.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           89 a          143 c          126 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001363             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:22677:18271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001363
VERSION     KCWK01001363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22677:18271"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67101.1"
                     /translation="DYYCCSRSSSSTYVF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           82 a          162 c          118 g          113 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac gttggtggtt ataactctgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaagtc atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagt ctgaggacga
      361 ggctgattat tactgttgtt cacgttcaag cagcagcact tacgtcttcg gtcctgggac
      421 ccggctcacc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001364             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18925:18860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001364
VERSION     KCWK01001364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18925:18860"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67102.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           85 a          158 c          125 g          100 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtggacac
      181 aggagctaca ccatcgcgtg gcatcagcag cagcaaggga aggcccctcg atacttgatg
      241 tggcttaaaa gtgatggcag ccacagcaag ggggacggga tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattatt gtcagacgtg ggatattggc atttgggtgt tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001365             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:24665:16627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001365
VERSION     KCWK01001365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24665:16627"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67103.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          130 g           95 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctcgggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001366             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:22269:7126
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001366
VERSION     KCWK01001366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22269:7126"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67104.1"
                     /translation="DYYCQVWDISSDHVLF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          139 c          140 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctccgcggcc tcctttgacc tgactcagcc
      121 acgctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa cttgtgaact ggtaccaaca gaggccaccg caggcccctg tgctggtcat
      241 gtatgctgat agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaatacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattagta gtgatcatgt gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001367             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:22323:15761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001367
VERSION     KCWK01001367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22323:15761"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67105.1"
                     /translation="DYYCDSWDTTGTHPVLF"
     J_segment       392..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          148 c          126 g          102 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagagctct ggggtgtctc caccatggcc tggactcctc
       61 tctggctcac cctcctcagt ctttgcacag gttctgtggt ttcctctggc ctgactcagg
      121 accctgcagt gtctgtggcc ttgggacaga ctgtcaggat cacctgccaa ggagacagcc
      181 tcagaaccag ttatgcaagc tggtaccagc agaagccagg ccaggcccct gtcctggtcg
      241 tctatggtaa caactaccgg ccctcaggga tcccagagcg attctctggc tccaactcaa
      301 gaaacacagc ttccttgacc atcactggga ctcaggtgga agatgaggct gactattact
      361 gtgactcctg ggacaccacc ggtacccatc ctgtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001368             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:7661:19435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001368
VERSION     KCWK01001368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7661:19435"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..336
                     /note="immunoglobulin light chain variable region"
     V_region        8..336
     V_segment       8..301
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67106.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       303..336
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           72 a          115 c           96 g           91 t
ORIGIN      
        1 acatgggggc tgccccgact cagcctccct ctgtgtccgg gtctcctgga cagtcggtca
       61 ccatctcctg cactggaacc agcagtgatg ttgggtatta taacgctgtg tcttggtacc
      121 aacagcatcc aggcaaagcc cccaaactca tgatttatga cgtcattaag cggccctcag
      181 gggtttctga tcgcttctct ggctccaagt ctggcgacac ggcctccctg accatctctg
      241 ggctccaggc tgaggatgag gctgattatt actgcagctc atatgcaggc agaaataatt
      301 ttttattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      361 tcactctctt cccg
//
LOCUS       KCWK01001369             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15255:17674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001369
VERSION     KCWK01001369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15255:17674"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67107.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          123 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagcgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001370             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:5124:9905
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001370
VERSION     KCWK01001370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5124:9905"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67108.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          163 c          111 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacatgtac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacacacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgacttacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaaa tgcttcaacg aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001371             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:5003:16495
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001371
VERSION     KCWK01001371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5003:16495"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67109.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       391..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           99 a          142 c          131 g           92 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gagctgactc
      121 aggcaccctc agtgtcagcg gcctcaggac agacggccag gatcacctgt ggcggagaca
      181 acattggaat taaaaatgtc cactggtacc agcagaagcc agcacaggcc cctgtggtag
      241 tcatctatgc tgataacaaa cggccctcag ggatccctga gcgactctct ggctccaact
      301 cagggaatat tgccaccctg accatcagca gggtcgaggc cggggatgag gcagactatt
      361 actgtcaggt gtgggacagt agtagtaaat gggtattcgg cggagggacc cggctaaccg
      421 tcctagatca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001372             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17551:14406
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001372
VERSION     KCWK01001372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17551:14406"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67110.1"
                     /translation="DYYYYSADSSGNWVF"
     J_segment       390..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           95 a          137 c          124 g          108 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccata gcctggattc
       61 ctctcctact ccccatcctc actttctgca caggctcttc agcctcctat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattaccaaa aaaatatgct tcttggttcc agctgaagcc aggccagtcc cctgtgatgg
      241 tcatctttga ggacagcaaa cggccctctg ggatccctga gagattcttt ggctccagtt
      301 tagggacagt ggccaccttg actataattg gggcccaggt ggaggatgaa gatgactact
      361 actattactc agcagacagt agtggtaatt gggtattcgc cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001373             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:6935:10030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001373
VERSION     KCWK01001373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:6935:10030"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67111.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          164 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agtagtgacc
      181 tcagtgttgg tagtaaaaac atctactggt accagctgaa gccagggagc gctcccaggt
      241 cattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga gcccgattat tactgtcagg tctatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001374             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:20151:3364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001374
VERSION     KCWK01001374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20151:3364"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..419
                     /note="immunoglobulin light chain variable region"
     V_region        89..419
     V_segment       89..382
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67112.1"
                     /translation="DYYCQSYDRSLSAVLF"
     J_segment       383..419
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           89 a          147 c          118 g          103 t
ORIGIN      
        1 acatggggca gcactcagga cagtctccag catggcctgg tctcctctcc tcctcaccct
       61 tctcattcac tgcacagggt cccgggccca gtctgtgctg acgcagccgc cctcagtgtc
      121 tggggcgccc gggcagaggg tcaccatctc ctgcactggg agcacctcca acattggaga
      181 ttattatgtg cagtggtacc aacagcttcc aggaacggcc cccagactcc tcatctatga
      241 aaataataag cgacgctcag ggacttctga tcgattctct ggctcccagt ctggtacctc
      301 agcctcgctg accataagtg gactccagtc tgaggatgag gctgactatt actgccagtc
      361 ttatgacaga agcttgagtg ctgtgttatt cggaggaggg acccggctga ccgtcctagg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001375             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:14096:13746
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001375
VERSION     KCWK01001375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14096:13746"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..417
                     /note="immunoglobulin light chain variable region"
     V_region        104..417
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67113.1"
                     /translation="DYFCQSGDSSGNHWVF"
     J_segment       392..417
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>466
                     /gene="IGLC"
BASE COUNT          105 a          130 c          131 g          100 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggaaaaat
      181 actggcaaaa aaatatactc agtggttcca gcagaagcca ggccaggccc ctctgctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag agattttcta ggtccagttc
      301 agggccaagg gatagcttga ccatcagtgg ggcccaggca gaagatgagg ctgactattt
      361 ctgtcaatca ggagacagca gtggtaatca ttgggtattc ggcggaggga cccggctagg
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001376             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:15025:7202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001376
VERSION     KCWK01001376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15025:7202"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67114.1"
                     /translation="DYYCAIGHMSGNYVF"
     J_segment       406..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          154 c          118 g          111 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca cacacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatataaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca tgagcggtaa ttatgtcttc ggttctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001377             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:14985:13235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001377
VERSION     KCWK01001377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14985:13235"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67115.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          157 c          124 g          105 t
ORIGIN      
        1 acatgggggc tgtggctcag gaagcagagc ctggagcatc tccaccatgg cctgggctcc
       61 actcctcctc accctcctcg ctcactgcac agggtcttgg gctgaggttg tgttcactca
      121 gccccattct gtgtcggggt ctccggggca gacggtcacc atctcctgca cccgcagcag
      181 tggcagcatt gacaacggct ttgtgtactg gtaccagcag cggccgggca gcgctcccac
      241 cactgtgatt tacaaagata accaaagacc ctctggggtc cctgatcggt tctctggctc
      301 catcgacagc tcctccaact ctgcctccct caccatctct ggactgaaat ctgaggacga
      361 ggctgactat tactgtcagt cttatgacag cagcagtgta ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001378             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:14763:14427
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001378
VERSION     KCWK01001378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:14763:14427"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67116.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          139 c          135 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 agcctcggtg tcagtgtccc cgggacagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtaaa aatgtgcact ggtaccagca ggagccaccg caggcccctg tgttggtcat
      241 cttttatgat aacaaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacatcgcc accctgacca tcagcgaggc cgaggccggg gatgaggctg actattactg
      361 tcagctgtgg gacagtagtg ttgatcatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001379             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:15396:19131
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001379
VERSION     KCWK01001379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15396:19131"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67117.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001380             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:21052:15163
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001380
VERSION     KCWK01001380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:21052:15163"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67118.1"
                     /translation="DINCHSADSSGNHWVF"
     J_segment       392..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          101 a          134 c          128 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgtt ctggagaaat
      181 actggcaaaa aaatatggtc agtggttcca gcagaagcca ggccaggccc ctgttgtggt
      241 gatctataag gacagtgaga ggccctcagg gatccctgag cgattctcta ggtccatttc
      301 agggacaaca attaccttga ccatctgtgg ggccccggca gaagatgagg ctgacattaa
      361 ctgtcattca gcagacagca gtggtaatca ttgggtcttc ggcggaggga cccggctaac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001381             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16586:4843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001381
VERSION     KCWK01001381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16586:4843"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67119.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          156 c          114 g          115 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaagctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggatccat
      181 cagtgatatt gggtcttata atgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 ccaactcata atttttgagg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct gacaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgctgctcat atgtaggcag caacacttac atcttcgatg ttgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01001382             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:14751:7831
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001382
VERSION     KCWK01001382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14751:7831"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67120.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          139 c          139 g           97 t
ORIGIN      
        1 acatggggct gactttggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactttacag gctctgcggc ctcctatgag gtgactcagc
      121 cacgctcagt gtccgtgtcc cccggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa aagtgtgcag tggtaccagc agacgccacc gcaggcccct gtactggtca
      241 tttatggtga tagggaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggatagtagt agtaaatatg tattattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001383             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:18101:17941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001383
VERSION     KCWK01001383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18101:17941"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67121.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       410..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          153 c          130 g          112 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac atcggggcgg gtttttatgt ttcctggtac cagcagttcc
      241 caggaacagc ccccaaactc ctcatctttg aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggttcct cagcctccct gaccatcact ggactccaat
      361 ctgaggatga ggctgattat tattgttcat catgggaaag cagcctgaat tgggtattcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001384             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:20558:12940
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001384
VERSION     KCWK01001384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20558:12940"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67122.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       393..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT          105 a          136 c          122 g          102 t
ORIGIN      
        1 acatgggggt gtggttctag gaggaagagc tctgggtgtc tcaccatgac ctggaccact
       61 gttctgctcc cctttctcac tctctgcaca ggctctgagg cctcctatga gctgacacag
      121 ccaccctcag tgtctgtgtc cccaggacag acggccagga tcacctgctc tggagaaata
      181 ctggcaaaaa aatatactca gtggttccag cagcagccag gccaggcccc tttcctggtg
      241 atatataaag acagtgagag gccctcaggg atccctgagc gattctctag ctccagttca
      301 gggacaacaa ttaccttgac catcagtggg gcccaggcag aagatgaggc tgactattac
      361 tgtcaatcag tagacagcag tggaaatctt ccgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001385             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17859:13834
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001385
VERSION     KCWK01001385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17859:13834"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..282
                     /note="immunoglobulin light chain variable region"
     V_region        8..282
     V_segment       8..245
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67123.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       246..282
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>320
                     /gene="IGLC"
BASE COUNT           64 a          104 c           80 g           72 t
ORIGIN      
        1 acatgggctc ctgcactgga accagcagtg acatcggtgg ttataactat gtctcctggt
       61 accaacaaca tccaggcaca gcccccaaac tcgtgattta tgaggtcaat cagcggccct
      121 caggggtctc tgatcgcttc tctggctcca agtctgacaa cacggcctcc ctgaccatct
      181 ctggcctcca gcctgaggac gaggctgatt attactgcag ctcgtatgca ggcagcgaca
      241 ctttcgtgtt attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      301 cctcggtcac tctcttcccg
//
LOCUS       KCWK01001386             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:15008:18761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001386
VERSION     KCWK01001386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15008:18761"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67124.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       396..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           94 a          149 c          117 g          109 t
ORIGIN      
        1 acatgggggg gagccaggga tcccttccaa tatcagcacc atggcctgga ctctgctcct
       61 cctccagttc ctcctcactt gctgcccagg gtccaattct caggctgtag tgactcagga
      121 gccctcaatg actgtgtccc caggagggac agtcactctc acctgtgctt ccagcactgg
      181 agcagtcacc agtggtcact ctccacactg gttccagcag aaacctggac aagcccccaa
      241 gacactgatt tataatacaa actacagaca ctcctggact cctgcccggt tctcaggctc
      301 cctccttggg ggtaaagttg ccctgacact gtcaggtgcg cagcctgagg atgaggctga
      361 gtattattgt ttactgtact atagtggtgc tcagctgtta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001387             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:4478:7919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001387
VERSION     KCWK01001387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:4478:7919"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67125.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          143 c          143 g           92 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttggaagtga agttgtgaac tggtaccagc ggaagccagc gcaggcccct gtgctggtca
      241 tctatgctga tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg gggtgaggct gactattact
      361 gtcaggtgtg ggacatgcgt agtgatcaac cgctattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001388             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:18860:12539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001388
VERSION     KCWK01001388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18860:12539"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67126.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       399..436
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           92 a          153 c          118 g          111 t
ORIGIN      
        1 atgggggcgg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcgcag cctgtgctga ctcagccaac ctccctctca
      121 gcatctcctg gagcatcagc cagactcacc tgcaccttgc gcagtggcat cagtgtcggt
      181 agttacagga tcttctggta ccagcagaag ccagggagtc ctccccggta tcttctgaac
      241 taccacacag actcagagaa acaccaggga tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cggccaatgc agggatttta ctcgtctctg gcctccagtc tgaggatgag
      361 gctgactatt actgtatgat ttggcacaac aatgcttatg tgttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001389             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:19915:13533
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001389
VERSION     KCWK01001389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19915:13533"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67127.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          143 c          133 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtcaa ctggtaccaa cagaagccac cgcagacccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgcggcct gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tactgatcat ccggtgttgt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001390             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:13545:5189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001390
VERSION     KCWK01001390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:13545:5189"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..268
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <233..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67128.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       269..305
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           72 a          106 c           83 g           82 t
ORIGIN      
        1 acatgggtca gccagactca gctgcacctt gagcagtggc aatgttggta gttacagcat
       61 attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact actactcaga
      121 ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga aagatgcttc
      181 agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg ctgactatta
      241 ctgtgccaca tggcacagca gcgcttctta catcttcggt gctgggaccc ggctcaccgt
      301 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01001391             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:22370:13199
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001391
VERSION     KCWK01001391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22370:13199"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..403
                     /note="immunoglobulin light chain variable region"
     V_region        58..403
     V_segment       58..366
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67129.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       369..403
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        404..>444
                     /gene="IGLC"
BASE COUNT           86 a          148 c          106 g          104 t
ORIGIN      
        1 acatggggga ctcctctcct cctcctgctc ctctctcact gcacaggttc cctctccaaa
       61 cctttgctga ctcagccggc ctccctctca gcatctcctg gagcttcagc cagtctcaca
      121 tgcaccttca gcggtggcat caatgttgct ggctaccaca tacactggta ccagcagaag
      181 ccagggagtc ctccccggta tcttctgaga tacaaatcag actcagatca gggccagggc
      241 tctggagtcc ccagccgctt ctctggatcc aaagatgctt cagcgaacac agggatttta
      301 cgcatctctg ggctccagtc tgaggatgag gctgactatt actgtgccat tgggcacagt
      361 agcggtgatt acatattcgg tggtgggacc cggctcaccg tcccaggtca gcccaaggct
      421 tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001392             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:13551:3078
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001392
VERSION     KCWK01001392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13551:3078"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67130.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          137 c          123 g          100 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca atgaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001393             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:17802:18424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001393
VERSION     KCWK01001393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17802:18424"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67131.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          164 c          122 g          108 t
ORIGIN      
        1 acatgggggg gtctgtgtcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001394             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:12270:17796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001394
VERSION     KCWK01001394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12270:17796"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67132.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       408..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          154 c          117 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcactg
      181 ttgctggcta ccatatatat tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat atctggactc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tgattatatc ttcggtgctg
      421 ggacccgtct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001395             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:23686:12905
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001395
VERSION     KCWK01001395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23686:12905"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67133.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcgatc actctcttcc
      481 cg
//
LOCUS       KCWK01001396             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:16767:20064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001396
VERSION     KCWK01001396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16767:20064"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67134.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       391..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          140 c          141 g           96 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactttac aggctctgcg gcctcctatg aggtgactca
      121 gccacgctca gtgtccgtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt aaaagtgtgc agtggtacca gcagacgcca ccgcaggccc ctgtactggt
      241 catttatggt gatagggaac ggccctcagg gatccctgag cgattctctg gctccaactc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggatagca gtagtaaata tgtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001397             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:18942:18030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001397
VERSION     KCWK01001397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18942:18030"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67135.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       373..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           94 a          140 c          113 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagttggcc aggatcacct gctctggaga agaattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtcca gatcatctat gaggacagta
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aagctgacta ctactgtttc tcaacagaca
      361 ccagtggtaa tcgggtattc ggcggaggga cccgtctaac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001398             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18822:13319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001398
VERSION     KCWK01001398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18822:13319"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67136.1"
                     /translation="DYYCQSYDSSLIGVLF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          152 c          127 g          113 t
ORIGIN      
        1 atgggggctc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac catctcctgc
      181 actgggagca gctccaacat tggagattat tatgtgcagt ggtatcagca ccttccagga
      241 acggccccca aactgctcat ctatgaaaat aataaacgac cctcaggggt ttctgatcga
      301 ttctctggct cccagtctgg aacctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagcagtt tgattggtgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001399             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:7227:17141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001399
VERSION     KCWK01001399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:7227:17141"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67137.1"
                     /translation="DYYCQVWDSTSDHYIF"
     J_segment       389..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          152 c          130 g           94 t
ORIGIN      
        1 acatggggtg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag gctctgcgac ctcctatgag ctgactcagc
      121 caccctcggt gtcagcggcc tcaggacaga cggccagggt cacctgtggg ggagacaaca
      181 ttggaactac gtttgtccac tggtaccagc agaatccacc gcaggcccct gtgcaggtca
      241 tctttgcgga taacaaacgg ccctcaggga tccctgaacg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtact agtgatcatt acatcttcgg tggtgggacc cgcctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001400             384 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:17023:15924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001400
VERSION     KCWK01001400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 384)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 384)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17023:15924"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..346
                     /note="immunoglobulin light chain variable region"
     V_region        13..346
     V_segment       13..309
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <277..>318
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67138.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       316..346
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        347..>384
                     /gene="IGLC"
BASE COUNT           70 a          125 c          110 g           79 t
ORIGIN      
        1 acatgggtct cccagcctgt ggtgactcag tcgtcctctg cctctgcctc cctgggagcc
       61 tcggtcaagc tcacctgcac tctgagcggt gggcacagcg actacaccat cgcatggcat
      121 cagcagcagc aagggaaggc ccctcggtat ttgatgtggc ttaaaagtga tggcagccac
      181 agcaaggggg acgggatccc tgatcgcttc tccggctcca gctccggggc tgagcgctac
      241 ctcaccatct ccaacctcca gtctgaggat gaggctgatt attactgtca gacctgggag
      301 actggcattc aggtgttcgg cggagggacc cggctaaccg tcctaggtca gcccaaggct
      361 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001401             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:15119:2927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001401
VERSION     KCWK01001401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15119:2927"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..265
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <231..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67139.1"
                     /translation="DYYCQSAENSAKYYIF"
     J_segment       276..306
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           88 a           92 c           91 g           73 t
ORIGIN      
        1 acatgggagt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagaaatac
       61 tggcaaaaaa atatggtcag tggttccagc agaagccagg tcaggcccct gtgttggtga
      121 tatataaaga cagtgagagg ccctcaggga tccctgagcg actctctagt tccagttcag
      181 gaacaacact taccttgacc atcactgggg cccaggcaga agatgaggct gactattact
      241 gtcaatcagc agagaacagt gctaagtatt atatattcgg tgctgggacc cggctcaccg
      301 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001402             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:23919:13707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001402
VERSION     KCWK01001402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:23919:13707"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..260
                     /note="immunoglobulin light chain variable region"
     V_region        4..260
     V_segment       4..220
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>232
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67140.1"
                     /translation="VYYCQVWDSSSEWVF"
     J_segment       224..260
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>298
                     /gene="IGLC"
BASE COUNT           64 a           86 c           89 g           59 t
ORIGIN      
        1 acatggggga gacaacattg gaactaaaac tgtgcactgg taccaacaga aggcagcaca
       61 ggcccctatg ctggtcatct ttgctgatag caaacggccc tcagggatcc ctgaccgatt
      121 ctctggctcc aactcaggga acaccggcac cctgaccatc agcggggtcg aggccgggga
      181 tgaggctgtc tattactgtc aggtgtggga cagtagtagt gagtgggttt tcggcggagg
      241 gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001403             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:23400:7395
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001403
VERSION     KCWK01001403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:23400:7395"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..403
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67141.1"
                     /translation="DYYCAMWHSSVYGLF"
     J_segment       405..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           95 a          155 c          115 g          115 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcatcaat
      181 gttggtagtt acagcatatt ctggtaccag cagaagccag ggagtcctcc ccgattcctt
      241 ctgtactact actcagactc aaataatcac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atacttcagc caatgcaggg cttttactga tctctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccatgtgg cacagtagtg tttatggctt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001404             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:19654:15932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001404
VERSION     KCWK01001404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19654:15932"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67142.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          161 c          116 g          108 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcgtcaatg
      181 tgggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacca gtcagactca aggaaacacc agggctctgg agtccccagc cacttctctg
      301 gatccaaaga tgcttcagcc aatgcaggac tattactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccctatggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001405             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15871:12517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001405
VERSION     KCWK01001405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15871:12517"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..401
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67143.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       406..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           89 a          152 c          121 g          112 t
ORIGIN      
        1 acatggggct tggatctcag gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccccgact
      121 cagactccct ctgtgtccgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgata ttgggtatta tcatgctgtg tcttggtacc agcatcatcc aggcaaagcc
      241 cccaaactca tgatttatga ggtcaataaa cggcccgcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccagac tgaggatgag
      361 gctgattatt actgcagctc atatggaggc agcaatagtt tattcttcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001406             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:15097:3410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001406
VERSION     KCWK01001406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15097:3410"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..439
                     /note="immunoglobulin light chain variable region"
     V_region        93..439
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67144.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>479
                     /gene="IGLC"
BASE COUNT           92 a          161 c          111 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctggggtc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagtagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtcctg ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001407             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:7904:7309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001407
VERSION     KCWK01001407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:7904:7309"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67145.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          140 c          137 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc actgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001408             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20805:7852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001408
VERSION     KCWK01001408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20805:7852"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..450
                     /note="immunoglobulin light chain variable region"
     V_region        117..450
     V_segment       117..413
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67146.1"
                     /translation="DYYCLEWHDSLSTGLF"
     J_segment       414..450
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           97 a          154 c          127 g          110 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactc cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcaacatctg gggcccccgg gcagagggtc accatctcct
      181 gcactgggaa cagccccaat atcggggcga attattatgt atcgtggtac cagcatttcc
      241 caggaacagc ccccaaactc ctcatctatg aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatcact gggctccagt
      361 ctgaggatga ggctgattat tactgcttag aatggcatga tagcctgagt actggcttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01001409             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:12515:20193
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001409
VERSION     KCWK01001409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12515:20193"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67147.1"
                     /translation="DYYCQVWDSSTRYAVF"
     J_segment       397..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          148 c          136 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcat tgccagcggc ctcaggacag acggccagga tcgcctgtgg gggagacagc
      181 attggaagtg aaaatgtgtt ctggtaccag cagaagccac ggcaggcccc tgtcctggtc
      241 atctatggtg atacgaaacg gccctcaggg atccctgagc gcttctctgg ctccatctct
      301 gggaacaccg ccaccctgac catcaacagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tactagatac gcggttttcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001410             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:18234:9743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001410
VERSION     KCWK01001410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18234:9743"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67148.1"
                     /translation="DYYCAAWDDGLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          156 c          127 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatggcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001411             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:10614:22887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001411
VERSION     KCWK01001411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:10614:22887"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..453
                     /note="immunoglobulin light chain variable region"
     V_region        114..453
     V_segment       114..410
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67149.1"
                     /translation="DYYCSAWDSSLRIRLF"
     J_segment       418..453
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           94 a          158 c          129 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgca
      181 ctgggagtag gagcagttcc aacatcgggg cggattatta tgtatcctgg taccagcagt
      241 tcccaggaac agcccccaaa ctcctcatct atgaaaataa taagcgaccc tcaggggttt
      301 ctgaccgatt ctctggctcc aagtctggtc cctcagcctc cctgaccatc tctggactcc
      361 aatctgagaa tgaggctgat tattactgct cagcatggga tagcagcctg cgcattcgct
      421 tattcggagg agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      481 ctctcttccc g
//
LOCUS       KCWK01001412             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:7146:11920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001412
VERSION     KCWK01001412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7146:11920"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..434
                     /note="immunoglobulin light chain variable region"
     V_region        110..434
     V_segment       110..391
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67150.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       400..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          153 c          136 g           96 t
ORIGIN      
        1 acatgggggc cctgtctggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggcc tcctcgctca ctgcacaggc tctgcgacct cctatgagct
      121 gactcagcca ccctcggtgt cagcggcctc aggacagacg gccaggatca cctgtggggg
      181 agacaacatt ggaactaaat atgtgcactg gtaccagcag aagccagcgc aggcccctgt
      241 gttggtcatc tatgctgata ccagacggcc ctcagggatc cctgagcgat tctctggctc
      301 caactcaggg aacaccgcca ccctgaccat caccggggtc gaggccgggt atgaggctga
      361 ctatttctgt caggtttggg acgatagtag tgatcatccg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001413             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:9095:16053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001413
VERSION     KCWK01001413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:9095:16053"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67151.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       373..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           95 a          140 c          113 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga agaattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtcca gatcatctat gaggacagta
      241 aacggtcctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aagctgacta ctactgtttc tcaacagaca
      361 ccagtggtaa tcgggtattc ggcggaggga cccgtctaac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001414             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:26077:9679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001414
VERSION     KCWK01001414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:26077:9679"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67152.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           89 a          154 c          121 g          109 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001415             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:13494:12190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001415
VERSION     KCWK01001415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:13494:12190"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..406
                     /note="immunoglobulin light chain variable region"
     V_region        88..406
     V_segment       88..374
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67153.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       375..406
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           88 a          139 c          119 g           98 t
ORIGIN      
        1 tcagaagcag agctctgggg tgtctccacc atggcctgga ctcctctctg gctcaccctc
       61 ctcagtcttt gcacaggttc tatggtttct tctgagctga ctcaggaccc tgcagtgtct
      121 gtggccttgg gacagacagt caggattacc tgccaaggag acagcctcag aagctcttat
      181 gcaagctggt accaacagag gccaggccag gcccctgtgc tggtcgtcta tggtaacaac
      241 taccggccct cagggatccc agagcgattc tctggctcct actcacgaaa cacagcttcc
      301 ttgaccatct ctggggctca ggtggaagat gaggctgact attactgtga ctcctgggac
      361 agcagcggaa cccaattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct
      421 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001416             277 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:8167:4472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001416
VERSION     KCWK01001416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 277)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8167:4472"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..239
                     /note="immunoglobulin light chain variable region"
     V_region        8..239
     V_segment       8..202
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <164..>211
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67154.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       203..239
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        240..>277
                     /gene="IGLC"
BASE COUNT           54 a           89 c           76 g           58 t
ORIGIN      
        1 acatggggtg cactggtacc agcacaagcc accgcaggcc cctatcctgg tcatctatta
       61 ttataccgaa cggccctcgg cgatccctga gcgattctct ggctccaaat cagggaacac
      121 cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt actgtcaggt
      181 gtgggacact actattgatc atggcttttt cggaggaggg acccggctga ccgtcctagg
      241 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001417             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:13712:15270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001417
VERSION     KCWK01001417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:13712:15270"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..391
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67155.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       392..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          153 c          117 g          103 t
ORIGIN      
        1 acatggggga cagaaggcag gactcaggac aatctccagc atggcctggt tccctctcgt
       61 cctcaccctc ctcactcact gtgcagggtc ctgggcccag tctgtgctga ctcagcctcc
      121 ctcagcgtct gaggccgcca ggaagagtgt caccatctcc tgttctggaa gcagctccaa
      181 catcggaagt aataatgtgt cctggtacca gcacctccca ggaacagctc ccaaactcct
      241 catctattat aatgatcaac gaggctcagg tgtctctgac cgattctctg gctccaagtc
      301 tggcacgtca gcctccctgg ccatcagtgg gctccagacc gaggatgagg ctgattatta
      361 ctgcgcagcg tgggatgata gcctgagcag ttacatcttc gctgctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001418             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:15097:7644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001418
VERSION     KCWK01001418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15097:7644"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..429
                     /note="immunoglobulin light chain variable region"
     V_region        84..429
     V_segment       84..390
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67156.1"
                     /translation="DYYCQVYDSSDVLF"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           93 a          156 c          112 g          106 t
ORIGIN      
        1 acatgggaga ggtagccgtg tccaccatgg ccctgactcc tctcctcctc ctgctcctct
       61 ctcactgcac aggttccctc tcccagcctg tgctgactca gccaccctcc ctgtctgcat
      121 ccccgggagc atcggccaga ctcccctgca ccctgagcag tgacctcaat attggtaata
      181 aaaacatgta ctggtaccag cagaagccag ggagcgctcc caagttattc ctgtactact
      241 actccgactc agacaagcag ctgggacctg gggtccccaa tcgagtctct ggctccaagg
      301 agacctcaag tcatacagcg tttttgctca tctctgggct ccagcctgag gacgaggccg
      361 attattactg tcaggtgtat gacagtagtg atgtattatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001419             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:16471:13129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001419
VERSION     KCWK01001419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16471:13129"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..425
                     /note="immunoglobulin light chain variable region"
     V_region        80..425
     V_segment       80..389
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67157.1"
                     /translation="DYYCALWYNSAWIF"
     J_segment       390..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          154 c          109 g          113 t
ORIGIN      
        1 acatggggag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc tcctctctca
       61 ctgcacaggt tccctgtcac agcctgtgct gactcagccg gcctccctct cagtatctcc
      121 tggaacatca gtcagactca cctgcacctt gcgcactggc atcaatgttg gtggctccta
      181 catattctgg taccaacaga agccagggcg tcctccccgg taccttctga actactactc
      241 agactcaaat aagggccagg gctctggagt ccccagccgc ttctctggat ccaaagatgc
      301 ttcagccaat gcaggacttt tactgatctc tgggctccag tctgaggatg aggctgacta
      361 ttactgtgcc ttatggtaca acagcgcttg gatattcggc ggagggaccc ggctaatcgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001420             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14695:14465
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001420
VERSION     KCWK01001420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14695:14465"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67158.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          163 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcgagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001421             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:12737:11065
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001421
VERSION     KCWK01001421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12737:11065"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67159.1"
                     /translation="DYHCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           97 a          160 c          114 g          105 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gtcagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgactacca cacacactgg taccaacaga agccagggag tcccccccgg tttcttctga
      241 gatacaaatc agacacagac aagggccagg ggtctggagt ccccagccgc ttctctggat
      301 ccaaagatac ttcagcgaac acaggcattt tagacatctc tgggctccag tctgaggatg
      361 aggctgacta tcactgtgcc attggtcaca gcagcggtcc atacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001422             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:23055:9505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001422
VERSION     KCWK01001422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23055:9505"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67160.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          157 c          119 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca cgaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctatgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tccggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttattcttcg ggggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001423             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:18880:17038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001423
VERSION     KCWK01001423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18880:17038"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67161.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          159 c          122 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccggca cctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcggtta catcttcggt
      421 tctgggaccc gactcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001424             323 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:13421:6721
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001424
VERSION     KCWK01001424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 323)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13421:6721"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..285
                     /note="immunoglobulin light chain variable region"
     V_region        8..285
     V_segment       8..247
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <210..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67162.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       249..285
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>323
                     /gene="IGLC"
BASE COUNT           69 a          104 c           75 g           75 t
ORIGIN      
        1 acatgggcac catctcctgt tctggaagca cctccaacat cggaagcaat aatgtatcct
       61 ggtaccagca gctcccagga acagctccca aactcctctt ttattataat gatcaacgag
      121 cctcaggtgt ctctgaccga ttctcttgct ccaagtctgg cacgtcagcc tccctggcca
      181 tcagtgggct ccagaccgag gatgaggctg attattactg cgcagcatgg gatgataacc
      241 tgagcggcta catcttcggt gctgggaccc ggctcaccgt cctaggtcag cccaaggctt
      301 cccccacggt cactctgttc ccg
//
LOCUS       KCWK01001425             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:22426:3660
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001425
VERSION     KCWK01001425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22426:3660"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..431
                     /note="immunoglobulin light chain variable region"
     V_region        110..431
     V_segment       110..391
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67163.1"
                     /translation="DYYCQVWDSSSEWVF"
     J_segment       395..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           89 a          150 c          137 g           93 t
ORIGIN      
        1 acatgggggc cctgtctggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggcc tcctcgctta ctgcacaggc tctgcgacct cctatgagct
      121 gactcagcca ccctcagtgt cagcggcctc aggacagacg gccaggatca cctgtggggg
      181 agacaacatt ggaactaaaa ctgtgcactg gtaccaacag aaggcagcgc aggcccctgt
      241 gctggtcatc tttgctgata ccaaacggcc ctcagggatc cctgaccgat tctctggctc
      301 caactcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga
      361 ctattactgt caggtgtggg acagtagtag tgagtgggtt ttcggcggag ggacccggct
      421 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001426             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:19348:15470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001426
VERSION     KCWK01001426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19348:15470"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..441
                     /note="immunoglobulin light chain variable region"
     V_region        94..441
     V_segment       94..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67164.1"
                     /translation="DYYCAIGHSSGNYIF"
     J_segment       408..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          157 c          120 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctat gctgactcag ccggcctcct
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcgc cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtttcttc
      241 tgagatacaa gtcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaagga tgcttcagcg aacacaggag ttttacgcat ctctggcctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg caattatatc ttcggtgctg
      421 ggacccggct aaccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001427             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:13402:4971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001427
VERSION     KCWK01001427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:13402:4971"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67165.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          146 c          129 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggacca ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001428             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:18542:9990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001428
VERSION     KCWK01001428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18542:9990"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..404
                     /note="immunoglobulin light chain variable region"
     V_region        80..404
     V_segment       80..367
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <329..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67166.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       369..404
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>442
                     /gene="IGLC"
BASE COUNT           85 a          133 c          129 g           95 t
ORIGIN      
        1 acatggggac ggtgcctcag ccatggcctg gacttttctc ctcctcggcc tccttgctta
       61 ctgcacaggc tctgcggcct cctatgatct gactcaggca ccctcgattt cagtgtcccc
      121 aggacagacg gccaggatca cctgtggggg agacaacatt ggaagtgaag ttgtgaactg
      181 gtaccagcag aagccaccgc aggcccctgt gttggtcatg tatgctgata gcgagcggcc
      241 ctcagggatc cctgagcgat tctctggctc caaatcaggg aacacggcca ccctgaccat
      301 cagcggggtc gaggccgggg atgaggctga ctattactgt caggtgtggg acatgaatag
      361 tcatcatctg ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc
      421 cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001429             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:9045:20641
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001429
VERSION     KCWK01001429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9045:20641"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..297
                     /note="immunoglobulin light chain variable region"
     V_region        8..297
     V_segment       8..260
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67167.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       264..297
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>335
                     /gene="IGLC"
BASE COUNT           72 a          102 c           91 g           70 t
ORIGIN      
        1 acatgggggc cttgggacac acagtcagga tgacctgcca aggagacagc ctcagaacct
       61 attatgcaag ctggtaccag cagaagccag gccaggtccc tgtgctggtc atctatggta
      121 acaactaccg gccctcaggg atcccaggcc gattctctgt ctcctggtca ggagacacag
      181 gttccttgac catcactgcg gctcaggtgg aagatgaggc tgactattac tgtaagtcct
      241 gggacagcag cggtacccat tatatcttcg gtgctgggac ccggctcacc gtcctaggtc
      301 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001430             271 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:8771:5275
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001430
VERSION     KCWK01001430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 271)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 271)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..271
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:8771:5275"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..233
                     /note="immunoglobulin light chain variable region"
     V_region        7..233
     V_segment       7..196
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <161..>205
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67168.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       197..233
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        234..>271
                     /gene="IGLC"
BASE COUNT           58 a           85 c           66 g           62 t
ORIGIN      
        1 acatgggcca gggagtcccc cccggtatct tctgagttac aaatcagact cagataaggg
       61 ccagggctct ggagtcccca gccgcttctc tggatccaaa aatggttcaa caaacacagg
      121 cattttacac atctctgggc tccagtctga ggatgaggct gactatttct gtgccattgg
      181 acacagcagc ggtccttaca tcttcggtac tgggacccgg ctcaccgtcc taggtcagcc
      241 caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01001431             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:18059:2629
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001431
VERSION     KCWK01001431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18059:2629"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67169.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           87 a          143 c          136 g          102 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtcaa ctggtaccaa cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgggc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgcggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tactgatcat ccggtgttgt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001432             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:19592:3224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001432
VERSION     KCWK01001432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19592:3224"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67170.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           89 a          162 c          120 g          108 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcgtcaatg
      181 tgggtagtta cagcgtattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacca gtcagactca aggaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc tgttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccctatggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001433             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:8060:15689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001433
VERSION     KCWK01001433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8060:15689"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67171.1"
                     /translation="DYYCAAWDDGLSGYIF"
     J_segment       414..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           98 a          158 c          123 g          109 t
ORIGIN      
        1 acatggggga agcgcagctt cagctgtggg tacagaaggc aggactcagg acaatctcca
       61 gcatggcctg gttccctctc gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc
      121 agtctgtgct gactcagcct ccctcaacgt ctgaggccgc caggaagagt gtcaccatct
      181 cctgttctgg aagcaactcc aacatcggaa attataatgt gtcctggtac cagcagctcc
      241 caggaacagc tcccaaactc ctcatctatt ataatgatca acgagcctca ggtgtctctg
      301 accgattctc tggctccaag tctggcacgt cagcctccct ggccatcagt gggctccaga
      361 ccgaggatga ggctgattat tactgcgcag catgggatga tggcctgagc ggttacatct
      421 tcgctgctgg gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCWK01001434             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:9550:10086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001434
VERSION     KCWK01001434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:9550:10086"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67172.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          162 c          124 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacgg ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001435             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:21201:15166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001435
VERSION     KCWK01001435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:21201:15166"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..261
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <233..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67173.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       268..305
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           69 a          105 c           82 g           87 t
ORIGIN      
        1 acatgggggg tctcctggac agtcggtcac catctcctgc actggatcca tcagtgatat
       61 tgggtcttat aatgctgtgt cttggtacca acagcatcca ggcaaagccc cccaactcat
      121 aatttttgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg gctccaagtc
      181 tgacaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg ctgattatta
      241 ctgctgctca tatgtaggca gcaacactta catcttcgat gttgggaccc ggctcaccgt
      301 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01001436             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:2035:12172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001436
VERSION     KCWK01001436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:2035:12172"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    69..399
                     /note="immunoglobulin light chain variable region"
     V_region        69..399
     V_segment       69..362
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <324..>371
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67174.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       364..399
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        400..>437
                     /gene="IGLC"
BASE COUNT           82 a          147 c          110 g           98 t
ORIGIN      
        1 acatggggag catggcctcg tctcctctcc tcctcaccct tctcattcac tgcacagggt
       61 cctgggccca gtctgtgctg acacagccgc cctcagtgtc tggggcccca gggcagaggg
      121 tcaccatctc ctgcactggg agcagctcca acattggagg ttattatata tcctggtacc
      181 agcagctccc aggaacggcc cccaaactcc tcgtctatga caataataag cgaccctcag
      241 gggtttctga ccgattctct ggctccaagt ctggttcctc agccaccctg accatcactg
      301 ggctccagac tgaggatgag gctgattatt actgccagtc ctatgacagc agtctgagtg
      361 ctcgggtatt cggcggaggg acccggctaa ccgtcctagg tcagcccaag gctgccccct
      421 cggtcactct cttcccg
//
LOCUS       KCWK01001437             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:13264:17268
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001437
VERSION     KCWK01001437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13264:17268"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..430
                     /note="immunoglobulin light chain variable region"
     V_region        85..430
     V_segment       85..393
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67175.1"
                     /translation="DYHCQVYDGSAVLF"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           87 a          152 c          122 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tctcactgca caggttccct ctcccagcct gtgctgactc agccaccctc cctgtctgca
      121 tccccgggag catcggccag actcccctgc accctgagta gtgacctcag tgttggtagt
      181 aaaaacatgt actggtacca gcagaagcca gggagcgctc ccaggttatt cctgtactac
      241 ttctccgact cagacaagca gttgggacct ggggtcccca atcgagtctc tggctccaag
      301 gagacctcaa gtaacacagc gtttttactc atctctgggc tccagcctga ggacgaggcc
      361 gattatcact gtcaggtgta tgacggtagt gctgttttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001438             329 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:16152:13869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001438
VERSION     KCWK01001438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 329)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16152:13869"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..291
                     /note="immunoglobulin light chain variable region"
     V_region        6..291
     V_segment       6..251
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <213..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67176.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       255..291
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>329
                     /gene="IGLC"
BASE COUNT           71 a           94 c           96 g           68 t
ORIGIN      
        1 acatgggaca gacggccagg atcacctgtg gaggagacaa cattggaagt gaagttgtca
       61 actggtacca gcagaggcca ccgcaggccc ctgtgctgct catctatgct gattatgaac
      121 ggccctcagg gatccctgac cgattctctg gctccaaatc agggaacacg gccaccctga
      181 ccatcagcgg agtcgaggcc ggggatgagg ctgactatta ttgtcaggtg tgggacattt
      241 atattgacca tccggtgtta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      301 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001439             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:3701:12020
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001439
VERSION     KCWK01001439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:3701:12020"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..385
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67177.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       389..421
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           92 a          144 c          132 g           91 t
ORIGIN      
        1 acatgggggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg gacccttctc
       61 ctcctcggcc tcctcgctta ctgcacaggc tctgcgacct cctatgaact gactcagtca
      121 ccctcagtgt cagcggcctc aggacagccg gccaggatca cctgtggggg agacaacatt
      181 ggaactaaaa ctgtgcactg gtaccagcag aagccaccgc agggccctgt attggtcatc
      241 tttgctgaca gtaaacggcc ctcagggatc cctgagcgat tctctggctc caactcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag taaatggata ttcggcgggg ggacccggct aaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001440             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:20301:19635
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001440
VERSION     KCWK01001440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20301:19635"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67178.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           86 a          164 c          122 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aaacagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac ccagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta tttctgccag ctgtttgaca gtagtgttgt gttcttcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001441             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:9459:11851
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001441
VERSION     KCWK01001441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9459:11851"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..435
                     /note="immunoglobulin light chain variable region"
     V_region        89..435
     V_segment       89..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67179.1"
                     /translation="DYYCSIGHSSGLYIF"
     J_segment       400..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           89 a          158 c          115 g          113 t
ORIGIN      
        1 acatggggtg gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccaa gcctatgctg actcagccgg cctccctctc
      121 agcatctcct ggagcatcag ccagtctcac atgcaccttc accggtggca tcaatgttgc
      181 tgtctaccac atacactggt accagcagaa gccagggagt cccccccggt ttcttctgag
      241 gtacaaatca gactcagata agggccaggg ctctggagtc cccagccgct tctctggatc
      301 cagtaatgct tcagcgaaca cagggatttt acgcatttct gggctccagt ctgaggatga
      361 ggctgactat tactgttcca ttggacacag cagcggtctt tacatcttcg gtgctgggac
      421 ccggctcacc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001442             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:9769:11108
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001442
VERSION     KCWK01001442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9769:11108"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67180.1"
                     /translation="DYYSAAWDDSLSGPVF"
     J_segment       411..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          158 c          128 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtttcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat cttttataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactc cgcagcatgg gatgatagcc tgagcggtcc ggtattcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001443             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:14800:19303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001443
VERSION     KCWK01001443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:14800:19303"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..428
                     /note="immunoglobulin light chain variable region"
     V_region        102..428
     V_segment       102..395
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <351..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67181.1"
                     /translation="DYHCSAGFGSGYSWQWVF"
     J_segment       396..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>470
                     /gene="IGLC"
BASE COUNT           92 a          150 c          131 g           97 t
ORIGIN      
        1 acatggggcc tggcttcaga agcagcatct gggacatgtc agccatggcc tggacgcctc
       61 tcctcctcag cctcctcgct cactgcacag gctctgtggc ctcctatgag ctgactcagc
      121 caccctcagt gtcggtgtcc ccaggacaga cagccagcat cacctgctct ggagataaat
      181 tggggaatgt ttatgcttat tggtaccagc agaagccagg ccaggcccct atactggtca
      241 tctacaaaga tagcaaccgg ccctcaggga tccctgaccg attctctggc tccaactcag
      301 ggaacacggc caccctgacc atcagcaggg tcgaggctgg ggatgaggcc gactatcact
      361 gttctgcagg ctttggcagt gggtacagct ggcagtgggt tttcggcgga gggacccggc
      421 taaccgtcgt aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001444             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:18179:20601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001444
VERSION     KCWK01001444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18179:20601"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..399
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67182.1"
                     /translation="EYYCLLYYSGAQLFF"
     J_segment       401..436
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           94 a          154 c          117 g          109 t
ORIGIN      
        1 acatggggag ctctggagcc agggatccct tccaatatca gcaccatggc ctggactctg
       61 ctcctcctcc agttcctcct cacttgctgc ccagggtcca attctcaggc tgtagtgact
      121 caggagccct caatgactgt gtccccagga gggacagtca ctctcacctg tgcttccagc
      181 actggagcag tcaccagtgg tcactctcca cactggttcc agcagaaacc tggacaagcc
      241 cccaagacac tgatttataa tacaaactac agacactcct ggactcctgc ccggttctca
      301 ggctccctcc ttgggggcaa agctgccctg acactgtcag gtgcgcagcc tgaggatgag
      361 gctgagtatt attgtttact gtactatagt ggtgctcagc tgttcttcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001445             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:16126:5706
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001445
VERSION     KCWK01001445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16126:5706"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..428
                     /note="immunoglobulin light chain variable region"
     V_region        103..428
     V_segment       103..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67183.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          137 c          135 g          104 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc ttctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001446             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:26611:16022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001446
VERSION     KCWK01001446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:26611:16022"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67184.1"
                     /translation="DYYCQVWDSSSYHRVF"
     J_segment       394..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          152 c          133 g           91 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca cagcctctgc gacctcctat ggactgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacgaccac gatcacctgt gggggagaca
      181 acattggaag taaatatgta cactggtacc agcagaagcc aacacaggcc cctgtgcagg
      241 tcatctatgc tgataccaga cggccctcag ggatccctga gcgcttctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagttatc atcgggtctt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001447             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:21871:14070
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001447
VERSION     KCWK01001447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:21871:14070"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..440
                     /note="immunoglobulin light chain variable region"
     V_region        92..440
     V_segment       92..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67185.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       403..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           92 a          155 c          118 g          113 t
ORIGIN      
        1 acatgggggt gtggggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc caagcctatg ctgactcagc cggcctccct
      121 ctcagcatct cctggagcat cagccagtct cacatgcacc ttcagcggtg gcatcaatgt
      181 tgctgactac cacgtacact ggtatcagca gaagccaggg agtccccccc ggtatcttct
      241 gaggtacaaa tcagactcag ataagggcct gggctctgga gtccccagcc gcttctctgg
      301 atccaaagat gcttcagcga atacagggat tttacacatc tctggtttcc agtctgagga
      361 tgaggctgac tattactgtg ccattggcca cggcagcggt gattacatct tcggtactgg
      421 gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01001448             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:9854:11407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001448
VERSION     KCWK01001448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9854:11407"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67186.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          152 c          118 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaacagtgtc gccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattatg atgatcaacg agcctcaagt gtctctgacc gattctctgg ctccaggtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagaggt tacatcttcg gtgatgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001449             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:7126:11110
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001449
VERSION     KCWK01001449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7126:11110"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..406
                     /note="immunoglobulin light chain variable region"
     V_region        88..406
     V_segment       88..374
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67187.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       375..406
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           89 a          139 c          119 g           97 t
ORIGIN      
        1 tcagaagcag agctctgggg tgtctccacc atggcctgga ctcctctctg gctcaccctc
       61 ctcagtcttt gcacaggatc tatggtttct tctgagctga ctcaggaccc tgcagtgtct
      121 gtggccttgg ggcagacagt caggattacc tgccaaggag acagcctcag aagttcttat
      181 gcaagctggt accaacagag gccaggccag gcccctgtgc tggtcgtcta tggtaacaac
      241 taccggccct cagggatccc agaacgattc tctggctcct actcccgaaa cacagcttcc
      301 ttgaccatca ctggggctca ggtggaagat gaggctgact attactgtga ctcctgggac
      361 agcagcggaa cccaattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct
      421 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001450             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:12115:16374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001450
VERSION     KCWK01001450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12115:16374"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67188.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          153 c          117 g          112 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcactgttg
      181 ctggctacca tatatattgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatatc tggactccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacaca gcagcggtga ttatatcttc ggtgctggga
      421 cccgtctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001451             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:15414:9209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001451
VERSION     KCWK01001451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15414:9209"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67189.1"
                     /translation="AYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          158 c          117 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cgatatcttc
      241 tgagattcaa atcggactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctgc ctattactgt gccattggac acagcagcgg tgattacatc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001452             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:18857:17017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001452
VERSION     KCWK01001452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:18857:17017"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67190.1"
                     /translation="DYYCAIGQNSDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           96 a          157 c          113 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcgat ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtttcttc
      241 ttaagtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacactggga ttttacgcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc aaaacagcga ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001453             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10285:6333
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001453
VERSION     KCWK01001453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10285:6333"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67191.1"
                     /translation="DYHCQVFDSRDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          159 c          124 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcatcctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactattcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtttgacag tcgtgatgtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001454             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:27799:10377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001454
VERSION     KCWK01001454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:27799:10377"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..430
                     /note="immunoglobulin light chain variable region"
     V_region        85..430
     V_segment       85..393
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67192.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           91 a          158 c          114 g          105 t
ORIGIN      
        1 acatggggag aggtagccgt gtccaccatg gccctgactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctcccagcct gtgctgactc agccaccctc cctgtctgca
      121 tccccgggag catcggccag actcccctgc accctgagca gtgacctcag tgttggtaat
      181 aaaaacatgt actggtacca acagaagcca gggagcgctc ccaggttatt cctgtactac
      241 tactccgact cagacaagca gctgggacct ggggtcccca atcgagtctc tggctccaag
      301 gagacctcaa ctaacacagc gtttttgctc atctctgggc tccagcctga ggacgaggcc
      361 gattattact gtcaggtgta tgacagtagt gctgtgttat tcggaggagg gacccgactg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001455             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:12862:9894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001455
VERSION     KCWK01001455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12862:9894"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..411
                     /note="immunoglobulin light chain variable region"
     V_region        63..411
     V_segment       63..374
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67193.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       377..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           86 a          152 c          109 g          102 t
ORIGIN      
        1 acatgggggc cctgactcct ctcctcctcc tgctcctctc tcactgcaca ggttccctct
       61 cccagcctgt gctgactcag ccaccctccc tgtctgcatc cccgggagca tcggccagac
      121 tcccctgcac cctgagcagt gacctcagtg ttggtagtaa aaacatgtac tggtaccaac
      181 agaagccagg gagcgctccc aggttattcc tgtactacta ctccgactca gacaagcagc
      241 tgggacctgg ggtccccaat cgagtctctg gctccaagga gacctcaagt aacacagcgt
      301 ttttgctcat ctctgggctc cagcctgagg acgaggccga ttattactgt caggtgtatg
      361 acagtagtgc taatgtctta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001456             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:12839:10080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001456
VERSION     KCWK01001456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12839:10080"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..312
                     /note="immunoglobulin light chain variable region"
     V_region        8..312
     V_segment       8..276
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <240..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67194.1"
                     /translation="HYYCCSYRSGNTWLF"
     J_segment       277..312
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>350
                     /gene="IGLC"
BASE COUNT           66 a          108 c           94 g           82 t
ORIGIN      
        1 acatgggagt gtccaagtct cttggacagt cggtcaccat ctcctgcact ggaaccagca
       61 gtgacattgg tggttatgat ggcgtctcct ggtaccagca gcactcaggg acagccccca
      121 gactcctgat ttatgatgtc actaagcggc cctcaggggt ctcggatcgc ttctctggct
      181 ccaagtctgg cgacacggcc tccctcacca tctctgggct ccagactgag gacgaggctc
      241 attattattg ttgctcatat aggagtggaa acacttggct attcggcgga gggacccggc
      301 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001457             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:6020:3429
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001457
VERSION     KCWK01001457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:6020:3429"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67195.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          164 c          124 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcggg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001458             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:14696:4378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001458
VERSION     KCWK01001458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14696:4378"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..401
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67196.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       403..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           85 a          155 c          121 g          113 t
ORIGIN      
        1 acatggggct gggatctcag gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggttcaggc tgccccgact
      121 cagcctccct ctgtgtccgg gtctcctgga cagtcggtca ccatctcctg cactggaacg
      181 agcagtgata ttggctatta taacgctgtg tcttggtacc aacagcatcc aggcaaagcc
      241 cccaaactca tcatttttga cgtcattaag cggccctcag gggtctctga tcgcttcgct
      301 gcctccaagt ctggcgacac ggcctccctg accatctctg ggctccgggc tgaggatgag
      361 gctgattatt actgcagctc atatgccggc agaaataatt ttttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001459             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:15270:22016
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001459
VERSION     KCWK01001459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15270:22016"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..232
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <188..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67197.1"
                     /translation="DYYCSTSYGSGSNWQYIF"
     J_segment       233..269
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           65 a           91 c           89 g           62 t
ORIGIN      
        1 acatggggga gataagcccg ggagtggatc tatttactgg taccagcaga agccaggcca
       61 ggtccctgtt ctggtcatct ataaaaatga caaccggccc tcagggatcc ctgagcgatt
      121 ctctggctcc aactcgggga gcacggccac cctgaccatc agcggggtcg aggctgggga
      181 tgaggccgac tattactgtt ctacaagcta tggcagtggg agcaactggc agtacatctt
      241 cggtactggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      301 gttcccg
//
LOCUS       KCWK01001460             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:19450:11791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001460
VERSION     KCWK01001460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19450:11791"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..412
                     /note="immunoglobulin light chain variable region"
     V_region        95..412
     V_segment       95..378
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67198.1"
                     /translation="DYYCYSSDSNSKWIF"
     J_segment       384..412
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>454
                     /gene="IGLC"
BASE COUNT          100 a          139 c          118 g           97 t
ORIGIN      
        1 acatggggtc aggaggcaga gctctgggtg tctcaccata gcctggattc ctctcctact
       61 ccccatcctc actttctgca caggctctgc agcctcctat gaaatgacac agccaccctc
      121 ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg cattgccaaa
      181 aaaatatgct tattggttcc cgcagaaggc aggccaaccc cctatggtga tcatctatga
      241 gggcaccaaa cggccctctg ggatccctgc gagattctct ggctccagct cagggacagt
      301 ggccaccttg actatcagtg gggcccaggt ggaggatgaa ggtgactact actgttactc
      361 atcagacagc aatagtaaat ggatattcga cggagggacc cggctgaccg tcgtaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001461             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:13549:10208
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001461
VERSION     KCWK01001461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13549:10208"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..401
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67199.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       406..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           90 a          154 c          121 g          109 t
ORIGIN      
        1 acatgggggg gggatctcag gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccccgact
      121 cagactccct ctgtgtccgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgata ttgggtatta tcatgctgtg tcttggtacc aacatcatcc aggcaaagcc
      241 cccaaactca tgatttatga ggtcaataaa cggcccgcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccagac tgaggatgag
      361 gctgattatt actgcagctc atatgcaggc agcaacactt tattcttcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001462             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:17939:9606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001462
VERSION     KCWK01001462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17939:9606"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67200.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          152 c          122 g          112 t
ORIGIN      
        1 acatgggggc ttggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatggagg cagcaatagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001463             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:4524:10064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001463
VERSION     KCWK01001463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4524:10064"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67201.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          158 c          114 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctg ttcccg
//
LOCUS       KCWK01001464             297 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:20478:15050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001464
VERSION     KCWK01001464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 297)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20478:15050"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..259
                     /note="immunoglobulin light chain variable region"
     V_region        8..259
     V_segment       8..219
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <187..>231
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67202.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       226..259
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        260..>297
                     /gene="IGLC"
BASE COUNT           67 a           89 c           76 g           65 t
ORIGIN      
        1 acatgggacc acatatactg gtaccaccag aagccaggga gtcccccccg gtatcttctg
       61 aggtacaaat cagactcaga taagggccag ggctctggag tccccagccg cttctctgga
      121 tccaaagatg cttcagcgaa cacagggatt ttacacatct ctggactcca gtctgaggat
      181 gaggctgact attactgtgc cattggacac agcagcggtg attatatctt cggtggtggg
      241 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01001465             281 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:3938:12991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001465
VERSION     KCWK01001465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 281)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:3938:12991"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..243
                     /note="immunoglobulin light chain variable region"
     V_region        7..243
     V_segment       7..206
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <174..>215
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67203.1"
                     /translation="DYYCAIGHSSGYIF"
     J_segment       207..243
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        244..>281
                     /gene="IGLC"
BASE COUNT           58 a           85 c           77 g           61 t
ORIGIN      
        1 acatggggta ccagcagaag ccagggagtc ctccccggta tcttctgaga tacaaatcag
       61 actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc agagatgctt
      121 cagcgaacac agggatttta cgcatctctg ggctccagtc tgaggatgag gctgactatt
      181 actgtgccat tgggcacagc agcggttaca tcttcggtgc tgggacccgg ctcaccgtcc
      241 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01001466             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:20869:15691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001466
VERSION     KCWK01001466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20869:15691"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67204.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       398..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          163 c          124 g          102 t
ORIGIN      
        1 acatggggga gcagagccct gaggagtctg caccatggcc tggaccccaa tcctcctcct
       61 cctcctcact ctcctccttc actgcacagg gtctctctcc cagcctgtgc tgactcagtc
      121 gccctctgcc tctgcctccc tgggagcctc ggtcaagctc acctgcactc tgagcagtgg
      181 ccactacagc tacaccatcg catggcatca gcagcagcaa gggaaggccc ctcggttctt
      241 gatgtggctt aagagtgatg gcagccacac caagggggac ggggtccctg atcgcttctc
      301 aggctccagc tccggggctg agcgctacct caccatctcc aacctccagt ctgaggatga
      361 ggctgattat tactgtcaga cctgggatat tggcatttgg gtattcggcg gagggacccg
      421 gctaatcgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001467             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:8684:11183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001467
VERSION     KCWK01001467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:8684:11183"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..275
                     /note="immunoglobulin light chain variable region"
     V_region        8..275
     V_segment       8..238
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <206..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67205.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       245..275
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>313
                     /gene="IGLC"
BASE COUNT           63 a           96 c           93 g           61 t
ORIGIN      
        1 acatgggact ctgagcggtg ggcacagcga ctacaccatc gcatggcatc agcagcagca
       61 agggaaggcc cctcggtatt tgatgtggct taaaagtgat ggcagccaca gcaaggggga
      121 cgggatccct gatcgcttct ccggctccag ctccggggct gagcgctacc tcaccatctc
      181 caacctccag tctgaggatg aggctgatta ttactgtcag acctgggaga ctggcattca
      241 ggtgttcggc ggagggaccc ggctaaccgt cctaggtcag cccaaggctg ccccctcggt
      301 cactctcttc ccg
//
LOCUS       KCWK01001468             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:23052:15918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001468
VERSION     KCWK01001468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23052:15918"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67206.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          157 c          126 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agccttcctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcggcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001469             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:13799:16182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001469
VERSION     KCWK01001469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13799:16182"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67207.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       412..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          162 c          125 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcccccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct cccagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gacgatagcc tgcgcggcta tatcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001470             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:13144:15243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001470
VERSION     KCWK01001470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13144:15243"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    131..452
                     /note="immunoglobulin light chain variable region"
     V_region        131..452
     V_segment       131..418
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67208.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       421..452
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>493
                     /gene="IGLC"
BASE COUNT           99 a          149 c          146 g           99 t
ORIGIN      
        1 acatgggaag cagtggggtc aacgcagagt acatgggggg gcctcaggag gcagcattga
       61 cggtgcctca gccatggcct ggacttttct cctcctcggc ctccttgctt actgcacaga
      121 ctctgcggcc tcctatgatc tgactcagcc accctcggtg tcagtgtccc caggacagac
      181 ggccaggatc acctgtgggg gagacaacat tggaagtgaa gttgtgaact ggtaccagca
      241 gaagccaccg caggcccctg tcctggtcat ctatgctaat aacgaacggc cctcagggat
      301 ccctgagcga ttctctggct ccaaatcagg gaacacggcc accctgacca tcagcggggt
      361 cgaggccggg gatgaggctg actattactg tcaggtgtgg ggcgttacta gtgatcatcc
      421 cttattcgga ggagggaccc ggctgaccgt ccaaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01001471             502 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22667:19430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001471
VERSION     KCWK01001471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 502)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 502)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..502
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22667:19430"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..464
                     /note="immunoglobulin light chain variable region"
     V_region        116..464
     V_segment       116..427
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <392..>436
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67209.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       428..464
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        465..>502
                     /gene="IGLC"
BASE COUNT          107 a          162 c          113 g          120 t
ORIGIN      
        1 acatgggcca gcaccgcagc ctgattgtga ctcttctggc aaagatccct gaaaaatttg
       61 accctggttt ctgccttagc atccaataat gtctgtgttt gcaggttccc tctccaagcc
      121 tatgctgact cagccggcct ccctctcagc aactcctgga gcatcagcca gtctcacatg
      181 caccttcagc ggtggcatca atgttgctgc ctaccacata cactggtacc agcagaagcc
      241 agggagtccc ccccggtatc ttctgactta caaatcagac tcagataagg gccagggctc
      301 tggagtcccc agccgcttct ctggatccaa aaatgcttca acgaacacag gcattttaca
      361 catctctggg ctccagtctg aggatgaggc tgactatttc tgtgccattg gacacagcag
      421 cggtccttac atcttcggtg ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc
      481 ccccacggtc actctgttcc cg
//
LOCUS       KCWK01001472             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10068:4449
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001472
VERSION     KCWK01001472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10068:4449"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..402
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67210.1"
                     /translation="DYSCCSYRSGNTWLF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           81 a          158 c          129 g          108 t
ORIGIN      
        1 acatgggggg ctggggtctc aggaggcagc gctctcggga cgtctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag tctgccctga
      121 ctcagcctcc ctcagtgtcc aagtctcttg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga cattggtggt tatgatggcg tctcctggta ccagcagcac tcagggacag
      241 cccccagact cctgatttat gatgtcacta agcggccctc aggggtctcg gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tcaccatctc tgggctccag actgaggacg
      361 aggctgatta ttcttgttgc tcatatagga gtggaaacac ttggctattc ggcggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001473             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:9908:15182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001473
VERSION     KCWK01001473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9908:15182"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..400
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67211.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           87 a          151 c          128 g          111 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg tcaccatctc ctgctctggg
      181 agcagctcca acatcggggc gggtttttat gtttcctggt accagcagtt cccaggaaca
      241 gcccccaaac tcctcatctt tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggttc ctcagcctcc ctgaccatca ctggactcca atctgaggat
      361 gaggctgatt attattgttc atcatgggaa agcagcctga attgggtatt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001474             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:6219:9710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001474
VERSION     KCWK01001474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6219:9710"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..404
                     /note="immunoglobulin light chain variable region"
     V_region        80..404
     V_segment       80..367
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <329..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67212.1"
                     /translation="DYHCQVWDLNSHHLLF"
     J_segment       369..404
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>442
                     /gene="IGLC"
BASE COUNT           83 a          136 c          127 g           96 t
ORIGIN      
        1 acatggggac ggtgcctcag ccatggcctg gacttttctc ctcctcggcc tccttgctta
       61 ctgcacaggc tctgcggcct cctatgatct gactcagcca ccctcgattt cagtgtcccc
      121 aggacagacg gccagggtca cctgtggggg agacaacatt gggagtgaag ttgtgaactg
      181 gtaccagcag aagccaccgc aggcccctgt gttggtcatc tatgctgata gcgagcggcc
      241 ctcagggatc cctgaacgat tctctggctc caaatcaggg aacacggcca ccctgaccat
      301 cagcggggtc gaggccgggg atgaggctga ctatcactgt caggtgtggg accttaatag
      361 tcatcatttg ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc
      421 cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001475             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:11326:17571
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001475
VERSION     KCWK01001475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11326:17571"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67213.1"
                     /translation="DYYCQVWDSTSDHVFF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          141 c          137 g           99 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 cgccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacgaca
      181 ttggaagtaa atatgtgcac tggtaccagc agaagccacc gcaggcccct gtgctggtca
      241 tctattatga tggcgaacgg ccctcaggga tccctgagcg attctctgac tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtact agtgatcatg tgtttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001476             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:16552:7660
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001476
VERSION     KCWK01001476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16552:7660"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67214.1"
                     /translation="DYYCSSYAGSNSLVF"
     J_segment       404..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          153 c          123 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg tcctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtagttata accgtgtctc ctggtaccaa catcacccag acaaagcccc
      241 caaagtcatg atttatgagg gcagtcagcg gccctcaggg gtctctgatc gcttctctgc
      301 ctccaagtct ggcaaaacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caatagtttg gttttcggcg gagggacccg
      421 gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001477             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18851:12178
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001477
VERSION     KCWK01001477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18851:12178"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67215.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          160 c          124 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagag gccagggagc gctcccaggt
      241 tattcctgta ttactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaggtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001478             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:7282:18408
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001478
VERSION     KCWK01001478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7282:18408"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67216.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           90 a          152 c          120 g          111 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgagctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgtagctca tatgcaggca gcaacagttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001479             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:15797:12696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001479
VERSION     KCWK01001479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15797:12696"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67217.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          154 c          119 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catatactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg ggtctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtgcc atcggacaca gcagcggtga ttatatcttc ggtgctggga
      421 cccggctcat cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001480             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:21467:7812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001480
VERSION     KCWK01001480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:21467:7812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67218.1"
                     /translation="DYYCQTWDTGIDVF"
     J_segment       394..430
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          157 c          121 g          102 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtgggcac
      181 aacagctaca ccatcgcatg gcatcagcag cagcaaggga aggcccctcg gtacttgatg
      241 tggcttaaaa gtgatggtag ccacagtaag ggggacggga tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatactggc attgatgtgt tcggaagcgg caccaagttg
      421 accgtcctcg gtcagcccaa ggcttccccc ttggtcactc tgttcccg
//
LOCUS       KCWK01001481             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:14903:8685
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001481
VERSION     KCWK01001481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14903:8685"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67219.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          158 c          121 g          110 t
ORIGIN      
        1 acatgggggc agcctcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgttgactc agcctccctc agcgtctgag gccgccggga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtatcct ggtaccaaca actcccagaa
      241 acggctccca aactcctcat gtattataat catcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cccttcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagtatgg gatgatagcc tgaccggtta catcttcggt
      421 actgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001482             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11368:7913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001482
VERSION     KCWK01001482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11368:7913"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67220.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          138 c          135 g          103 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001483             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:13191:10770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001483
VERSION     KCWK01001483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13191:10770"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67221.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          149 c          117 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tgttcccg
//
LOCUS       KCWK01001484             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:7764:3807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001484
VERSION     KCWK01001484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:7764:3807"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67222.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          156 c          128 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctatgaaa atgataaccg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct gattcctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cttgagtgtt gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001485             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:23129:2410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001485
VERSION     KCWK01001485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23129:2410"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67223.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          156 c          111 g          117 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcttc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttgctaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaacga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001486             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16474:7031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001486
VERSION     KCWK01001486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16474:7031"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67224.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           87 a          157 c          128 g          109 t
ORIGIN      
        1 acatgggggg cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccgggaag agggtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcgccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01001487             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:9161:7770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001487
VERSION     KCWK01001487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9161:7770"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..250
                     /note="immunoglobulin light chain variable region"
     V_region        12..250
     V_segment       12..213
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <181..>222
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67225.1"
                     /translation="DYYCAIGHSSGYIF"
     J_segment       214..250
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        251..>288
                     /gene="IGLC"
BASE COUNT           60 a           88 c           78 g           62 t
ORIGIN      
        1 acatgggcac actggtacca gcagaagcca gggagtcctc cccggtatct tctgagatac
       61 aaatcagact cagataaggg ccagggctct ggagtcccca gccgcttctc tggatccaga
      121 gatgcttcag cgaacacagg gattttacgc atctctgggc tccagtctga ggatgaggct
      181 gactattact gtgccattgg gcacagcagc ggttacatct tcggtgctgg gacccggctc
      241 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01001488             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:6653:16775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001488
VERSION     KCWK01001488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6653:16775"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..450
                     /note="immunoglobulin light chain variable region"
     V_region        130..450
     V_segment       130..414
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67226.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       415..450
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>489
                     /gene="IGLC"
BASE COUNT          101 a          150 c          135 g          103 t
ORIGIN      
        1 acatggggaa gagaggccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactcccca tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaagatca cctgctctgg agatgcactg ccaaaaaaat atgcttattg gttccagcag
      241 aagccaggcc agtcccctgt gttgatcatc gatgaggaca ccaaacggcc ctctgggatc
      301 cctgagagat tctctggctc cagctcaggg acagtggcca ccttgactat cagtggggcc
      361 caggtggagg atgaagctga ctactactgt tactcagcag acagcagtgg ttatggctta
      421 ttcggaggag ggacccggct gaccgtccta cgtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCWK01001489             503 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:14201:11989
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001489
VERSION     KCWK01001489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 503)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 503)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..503
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14201:11989"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..465
                     /note="immunoglobulin light chain variable region"
     V_region        117..465
     V_segment       117..401
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>437
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67227.1"
                     /translation="DYYCQSYDSQSYDTSLSVRVF"
     J_segment       430..465
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        466..>503
                     /gene="IGLC"
BASE COUNT           87 a          165 c          135 g          116 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac atcggggcgg gttattatgt gcggtggtac cagcagcttc
      241 caggaacggc cccccaactc ctcatctatg atacttataa gcgaccctca ggggtttctg
      301 atcgaatctc tggctccaag tctggtacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag ccagtcctat gacaccagtt
      421 tgagtgttcg ggttttcggc ggtgggaccc ggctaaccgt cctaggtcag cccaaggctg
      481 ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001490             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:11852:6759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001490
VERSION     KCWK01001490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11852:6759"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..263
                     /note="immunoglobulin light chain variable region"
     V_region        4..263
     V_segment       4..225
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67228.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       231..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           64 a           87 c           93 g           57 t
ORIGIN      
        1 acatggggga gacaagattg gaagtgaagt tgtgaactgg taccagcaga agccagcgca
       61 cgcccctgtg ctggtcatct atgctaatag cgaacggccc tcagggatcc ctgagcgatt
      121 ctctggctcc aaatcaggga acacggccac cctgaccatc agcggggtcg aggccggggg
      181 tgaggctgac tattactgtc aggtgtggga catgcgtagt gatcaaccgc tattcggcgg
      241 agggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01001491             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:21841:16219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001491
VERSION     KCWK01001491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21841:16219"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67229.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          141 c          137 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001492             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:16907:4370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001492
VERSION     KCWK01001492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16907:4370"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67230.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           92 a          158 c          114 g          109 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgtttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggg ggggggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01001493             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:24675:15846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001493
VERSION     KCWK01001493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:24675:15846"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67231.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          142 c          127 g          101 t
ORIGIN      
        1 acaggggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gcaaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001494             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:9908:5432
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001494
VERSION     KCWK01001494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9908:5432"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67232.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       414..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           93 a          156 c          125 g          114 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca cttcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag attattttgt gcagtggtac cagcaccttc
      241 caggaacggc ccccaaactc ctcatctatg aaaataataa gcgaccctca gggatttctg
      301 atcgattctc tggctcccag tctggaacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagtttgatt gctgtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01001495             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:25004:12226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001495
VERSION     KCWK01001495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:25004:12226"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67233.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          162 c          119 g          109 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt aataaaaaca tgtactggta ccaacagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caactaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtatgacagt agtgctgtgt tattcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01001496             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:9063:15003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001496
VERSION     KCWK01001496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:9063:15003"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..297
                     /note="immunoglobulin light chain variable region"
     V_region        8..297
     V_segment       8..259
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67234.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       261..297
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>335
                     /gene="IGLC"
BASE COUNT           72 a          106 c           79 g           78 t
ORIGIN      
        1 acatgggcag gaagagtgtc accatctcct gttctggaag cacctccaac atcggaagca
       61 ataatgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc ttttattata
      121 atgatcaacg agcctcaggt gtctctgacc gattctcttg ctccaagtct ggcacgtcag
      181 cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac tgcgcatcat
      241 gggatgatac cctgagcggc tacatcttcg gtgctgggac ccggctcacc gtcctaggtc
      301 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001497             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:24370:21033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001497
VERSION     KCWK01001497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:24370:21033"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..373
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67235.1"
                     /translation="AYYCQVWDGDSDHYIF"
     J_segment       379..416
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           92 a          146 c          125 g           91 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacccttc tcctcctcgg
       61 cctcctcgct cactgcacag actctgcgac ctcctatgag ctgactcagc caccctcggt
      121 gtcaacggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca ttggaactaa
      181 ttttgtgcac tggtaccagc agaagccagc gcaggcccct atgcaggtca tctatgctga
      241 taacaaacgg ccctcaggga tccctgagag attctctggc tccaactcag ggaacaccgc
      301 caccctgacc atcagcggag tcgaggccgg ggatgaggct gcctattact gtcaggtgtg
      361 ggacggtgat agtgatcatt acatcttcgg tgctgggacc cggctcaccg tcctaggtca
      421 gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001498             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16641:4739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001498
VERSION     KCWK01001498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16641:4739"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..406
                     /note="immunoglobulin light chain variable region"
     V_region        58..406
     V_segment       58..368
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67236.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       372..406
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           86 a          151 c          109 g           98 t
ORIGIN      
        1 acatggggga ctcctctcct cctcctgctc ctctctcact gcacaggttc cctctcccag
       61 cctgtgctga ctcagccacc ctccctgtct gcatccccgg gagcatcggc cagactcccc
      121 tgcaccctga gcactgacct cagtgttggt ggtaaaaaca tgtactggta ccagcagaag
      181 ccaggaagcg ctcccaggtt attgctgtat taccactccg actcagacaa gcagctggga
      241 cctggggtcc ccaatcgagt ctctggctcc aaggagacct caagtaacac agcgtttttg
      301 ctcatctctg ggctccagcc tgaggacgag gccgattatt actgtcaggt gtatgacagt
      361 agtgccaaca cgttattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct
      421 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001499             323 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:6982:16005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001499
VERSION     KCWK01001499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 323)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:6982:16005"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..285
                     /note="immunoglobulin light chain variable region"
     V_region        8..285
     V_segment       8..245
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67237.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       249..285
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>323
                     /gene="IGLC"
BASE COUNT           69 a           91 c           95 g           68 t
ORIGIN      
        1 acatgggggc caggatcacc tgtggaggag acaacattgg aagtgaagtt gtcaactggt
       61 accagcagaa gccaccgcag gcccctgtgc tggtcatcta tgctgattat gaacggccct
      121 cagggatccc tgaccgattc tctggctcca aatcagggaa cacggccacc ctgaccatca
      181 gcggagtcga ggccggggat gaggctgact attattgtca ggtgtgggac atttatattg
      241 accatccggt gttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg
      301 ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001500             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:13437:19518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001500
VERSION     KCWK01001500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13437:19518"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..439
                     /note="immunoglobulin light chain variable region"
     V_region        106..439
     V_segment       106..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67238.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       403..439
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          106 t
ORIGIN      
        1 acatggggct ggggtctcag gaggcagcgc tctcgggaca tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagcctcgct cagtgtctgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgaca tcggtggtta taactatgtc tcctggtacc aacaacatcc agacacagcc
      241 cccaaactcg tgatttatga ggtcaatcag cggccctcag gggtctctga tcgcttctct
      301 ggctccaagt ctgacaacac ggcctccctg accatctctg gcctccagcc tgaggacgag
      361 gctgattatt actgcagctc atatgcaggc agcgacactt tcgtgttatt cggaggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001501             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:10250:20602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001501
VERSION     KCWK01001501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:10250:20602"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67239.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          158 c          126 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat caattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcggcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001502             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:18444:10916
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001502
VERSION     KCWK01001502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18444:10916"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67240.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          162 c          112 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagttacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaaa tgcttcaacg aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001503             406 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:21809:3500
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001503
VERSION     KCWK01001503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 406)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21809:3500"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    47..368
                     /note="immunoglobulin light chain variable region"
     V_region        47..368
     V_segment       47..332
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <296..>340
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67241.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       336..368
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        369..>406
                     /gene="IGLC"
BASE COUNT           85 a          123 c          114 g           84 t
ORIGIN      
        1 acatgggctc ctcggcctcc tcgcttactg cacaggctct gcgacctcct atgaattgac
       61 tcagtcattc tcagtgtcag cggcctcagg acagccggcc aggatcacct gtgggggaga
      121 caacattgga actaaaactg tgcactggta ccaacagaag ccaccgcagg gccctgtatt
      181 ggtcatcttt gctgatagta gacggccctc agggatccct gagcgattct ctggctccaa
      241 ctcagggaac accgccaccc tgaccatcag cagggtcgag gccggggatg aggctgacta
      301 ttactgtcag gtgtgggaca gtagtagtaa atggatattc ggcgggggga cccggctaac
      361 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001504             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:14887:5750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001504
VERSION     KCWK01001504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14887:5750"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67242.1"
                     /translation="DINCHSADSSGNHWVF"
     J_segment       392..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          102 a          133 c          128 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgtt ctggagaaat
      181 actggcaaaa aaatatggtc agtggttcca gcagaagcca ggccaggccc ctgttgtggt
      241 gatatataag gacagtgaga ggccctcagg gatccctgag cgattctcta ggtccatttc
      301 agggacaaca attaccttga ccatctgtgg ggccccggca gaagatgagg ctgacattaa
      361 ctgtcattca gcagacagca gtggtaatca ttgggtcttc ggcggaggga cccggctaac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001505             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:24581:10386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001505
VERSION     KCWK01001505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:24581:10386"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67243.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           94 a          142 c          125 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaagatc acctgctctg gagatgcact
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 cgatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001506             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:12059:3764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001506
VERSION     KCWK01001506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12059:3764"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67244.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          140 c          135 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga ttacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001507             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:16086:18503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001507
VERSION     KCWK01001507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16086:18503"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67245.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           89 a          151 c          121 g          112 t
ORIGIN      
        1 acatggggtt ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatggaggca gcaatagttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001508             348 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:5087:17811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001508
VERSION     KCWK01001508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 348)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5087:17811"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..310
                     /note="immunoglobulin light chain variable region"
     V_region        6..310
     V_segment       6..271
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <241..>282
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67246.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       273..310
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        311..>348
                     /gene="IGLC"
BASE COUNT           72 a          104 c           94 g           78 t
ORIGIN      
        1 acatggggag catcggccag actcccctgc accctgagca gtgacctcag tgttggtagt
       61 aaaaacatgt actggtacca gcagaagcca gggagcgctc ccaggttatt cctgtactac
      121 tactccgact cagacaagca gctgggacct ggggtcccca atcgagtctc tggctccaag
      181 gagacctcaa gtaacacagc gtttttgctc atctctgggc tccagcctga ggacgaggcc
      241 gattatttct gccaggtgtt tgacagtagt gttgtgttct tcggaggagg gacccgactg
      301 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001509             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:24121:18593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001509
VERSION     KCWK01001509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:24121:18593"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..297
                     /note="immunoglobulin light chain variable region"
     V_region        8..297
     V_segment       8..260
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67247.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       265..297
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>335
                     /gene="IGLC"
BASE COUNT           68 a          105 c           87 g           75 t
ORIGIN      
        1 acatgggcgg gcagagtgtc accatctcct gctctggaag cagctccaat attggaagta
       61 attctgtata ctggtaccag cagttcccag gaacggcccc caaactcctc atctattata
      121 gtaatcagcg accctcaggg gtccctgacc gagtctctgg ctctaagtcg ggcacctcag
      181 cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac tgtgcagcat
      241 gggatgacag cctgagaagt ccgctattcg gcggagggac ccggctgacc gtcctaggtc
      301 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001510             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:28015:6720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001510
VERSION     KCWK01001510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:28015:6720"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..387
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67248.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       393..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          150 c          120 g          105 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gcatctgggg cccccgggca gagggtcacc atctcctgca ctgggagcag ctccaacatc
      181 ggggcgggtt attatgtatc ctggtaccag cagttcccag gaacagcccc caaactcctc
      241 atctatgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggtacctcag cctccctgac catcactgga ctccaatctg aggatgaggc tgattattac
      361 tgctcagcat gggatagcag cctgagtatt aattacatct tcggtggtgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01001511             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:5611:9224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001511
VERSION     KCWK01001511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5611:9224"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67249.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gttcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001512             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:4464:12036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001512
VERSION     KCWK01001512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:4464:12036"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67250.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          150 c          115 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcac agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001513             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:22671:17001
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001513
VERSION     KCWK01001513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22671:17001"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..265
                     /note="immunoglobulin light chain variable region"
     V_region        73..265
     V_segment       73..226
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67251.1"
                     /translation="DYYCQSYDSSLSVYIF"
     J_segment       228..265
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           58 a           95 c           74 g           76 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcat ctatgaaaat aataagcgac cctcagggat ttctgatcga
      121 ttctctggct cccagtctgg tacctcagtc tccctgacca tcactggact ccagtctgag
      181 gatgaggctg attattactg ccagtcctat gacagcagct tgagtgttta catcttcggt
      241 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      301 ccg
//
LOCUS       KCWK01001514             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:17203:9615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001514
VERSION     KCWK01001514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17203:9615"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67252.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          156 c          120 g          110 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatgt tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacgcttt attcttcgga cgagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001515             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:8138:13855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001515
VERSION     KCWK01001515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8138:13855"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67253.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       394..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           94 a          150 c          115 g          108 t
ORIGIN      
        1 acatggggga gccagggatc ccttccaata tcagcaccat ggcctggact ctgctcctcc
       61 tccagttcct cctcacttgc tgcccagggt ccaattctca ggctgtagtg actcaggagc
      121 cctcaatgac tgtgtcccca ggagggacag tcactctcac ctgtgcttcc agcactggag
      181 cagtcaccag tggtcactct ccacactggt tccagcagaa acctggacaa gcccccaaga
      241 cactgattta taatacaaac tacagacact cctggactcc tgcccggttc tcaggctccc
      301 tccttggggg taaagctgcc ctgacactgt caggtgcgca gcctgaggat gaggctgagt
      361 attattgttt actgtactat agtggtgctc agctgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001516             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:10679:14219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001516
VERSION     KCWK01001516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10679:14219"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..385
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67254.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       387..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           84 a          148 c          125 g          105 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gcatctgggg cccccgggca gagggttacc atctcctgca ctgggagcag ctccaacatc
      181 ggggcgggtt tttatgtgtc ctggtaccag cagttccctg ggacagcccc caaactcctc
      241 atctttgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggttcctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgctcatcat gggaaagcag cctgaattgg gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001517             499 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:4546:8849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001517
VERSION     KCWK01001517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 499)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4546:8849"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    131..461
                     /note="immunoglobulin light chain variable region"
     V_region        131..461
     V_segment       131..422
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <389..>433
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67255.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       424..461
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        462..>499
                     /gene="IGLC"
BASE COUNT           92 a          157 c          136 g          114 t
ORIGIN      
        1 acatgggatc aacgcagagt acatggggct gcttcagctg tgggcacagg aggcagcact
       61 caggacagtc tccagcatgg cctggtctct ccttctcact ctgctggttc actgcacagg
      121 gtcctgggcc cagtctgtgc tgacgcagcc gccctcagca tctggggccc ccgggcagag
      181 ggttaccatc tcctgcactg ggagcagctc caacatcggg gcgggttttt atgtgtcctg
      241 gtaccagcag ttccctggaa cagcccccaa actcctcatc tttgaaaata ataagcgacc
      301 ctcaggggtt tctgaccgat tctctggctc caagtctggt tcctcagcct ccctgaccat
      361 cactggactc cagtctgagg atgaggctga ttattactgc tcatcatggg aaagcagcct
      421 gaattgggtt ttcggcggag ggacccggct gaccgtccta ggtcagccca aggctgcccc
      481 ctcggtcact ctcttcccg
//
LOCUS       KCWK01001518             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:10964:9596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001518
VERSION     KCWK01001518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10964:9596"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67256.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          157 c          127 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcagcact cagagacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tactgttgct catataggag tggaaatact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001519             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:13787:10628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001519
VERSION     KCWK01001519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13787:10628"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..403
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67257.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           86 a          161 c          121 g          112 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggta gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggttcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattattt ctgccaggtg tttgacagta gtgttgtgtt cttcggagga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001520             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10001:11701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001520
VERSION     KCWK01001520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10001:11701"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67258.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           82 a          161 c          122 g          103 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtggccac
      181 tacagctaca ccatcgcatg gcatcagcag cagcaaggga aggcccctcg gttcttgatg
      241 tggcttaaga gtgatggcag tcacaccaag ggggacgggg tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatattggc atttgggtat tcggcggagg gacccggcta
      421 atcgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001521             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:27470:8247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001521
VERSION     KCWK01001521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:27470:8247"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67259.1"
                     /translation="DYYCATWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          164 c          109 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccacatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001522             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16363:10804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001522
VERSION     KCWK01001522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16363:10804"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67260.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          158 c          124 g          113 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagag gccagggagt gctcccaggt
      241 tattcctgta ttactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaggtaaca cagcgttttt gctcatttct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001523             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18947:7991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001523
VERSION     KCWK01001523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18947:7991"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67261.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          157 c          121 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaataa tgtgtcctgg taccagcacc tcccaggaac
      241 agctcccaaa ctcctcatct attataatga tcaacgaggc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctgcca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcgtggga tgatagcctg agcagttaca tcttcgctgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01001524             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:13873:4959
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001524
VERSION     KCWK01001524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13873:4959"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67262.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          156 c          122 g          103 t
ORIGIN      
        1 acatgggggg ctcaggaagc agagcctgga gcatctccac catggcctgg gctccactcc
       61 tcctcaccct cctcgctcac tgcacagggt cttgggctga ggttgtgttc actcagcccc
      121 attctgtgtc ggggtctccg gggcagacgg tcaccatctc ctgcacccgc agcagtggca
      181 gcattgacaa cggctttgtg tactggtacc agcagcggcc gggcagcgct cccaccactg
      241 tgatttacaa agataaccaa agaccctctg gggtccctga tcggttctct ggctccatcg
      301 acagctcctc caactctgcc tccctcacca tctctggact gaaatctgag gacgaggctg
      361 actattactg tcagtcttat gacagcagca gtgtattatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001525             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:20721:14055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001525
VERSION     KCWK01001525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20721:14055"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67263.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          162 c          109 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggtttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001526             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:16451:19614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001526
VERSION     KCWK01001526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16451:19614"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67264.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          162 c          124 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcggg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001527             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:10186:8666
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001527
VERSION     KCWK01001527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10186:8666"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..365
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <329..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67265.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       369..401
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>439
                     /gene="IGLC"
BASE COUNT           89 a          139 c          122 g           89 t
ORIGIN      
        1 acatggggac ggtgcctcag ccatggcctg gacccttctc ctcctcggcc tcctcgctta
       61 ctgcacaggc tctgcgacct cctatgaatt gactcagtca ccctcagtgt cagcggcctc
      121 aggacagccg gccaggatca cctgtggggg agacaacatt ggaactaaaa ctgtgcactg
      181 gtaccaacag aagccaccgc agggccctct attggtcatc tttgctgata gtagacggcc
      241 ctcagggatc cctgagcgat tctctggctc caactcaggg aacaccgcca ccctgaccat
      301 cagcagggtc gaggccgggg atgaggctga ctattactgt caggtgtggg acagtagtag
      361 taaatggata ttcggcgggg ggacccggct aaccgtccta ggtcagccca aggctgcccc
      421 ctcggtcact ctcttcccg
//
LOCUS       KCWK01001528             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:25858:11891
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001528
VERSION     KCWK01001528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:25858:11891"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67266.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       390..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          146 c          120 g          105 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagaactct gggtcctctc caccatggcc tggacccctc
       61 ccctgctcat cctcctcact ctctgcacag gttccgtggt ttcctctgag ctgactcagg
      121 agcctgcatt gtctgtggcc ttgggacaaa cagtcaggat gacctgccaa ggagacagcc
      181 tcaaaaccta ttatgcaagc tggtaccagc agaagccagg ccaggtccct gtgctggtca
      241 tctatggtaa taactaccgg ccctcaggga tcccaggccg attctctgtc tcctggtcag
      301 gaaacacagg ttccttgacc atcactgcgg ctcaggtgga agatgaggct gactattact
      361 gtaagtcctg ggacagcagt ggtacccatt acatcttcgg tgctgggacc cggctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001529             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:22589:6778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001529
VERSION     KCWK01001529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22589:6778"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67267.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          151 c          116 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctaccgacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001530             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:13493:18086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001530
VERSION     KCWK01001530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13493:18086"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..438
                     /note="immunoglobulin light chain variable region"
     V_region        112..438
     V_segment       112..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67268.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       406..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>480
                     /gene="IGLC"
BASE COUNT           87 a          155 c          127 g          111 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggtacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcagc ctccctcagc gtctgaggcc gccaggaaga gtgtctccat ctcctgttct
      181 ggaagcagct ccaacatcgg aagtcatagt gtctcctggt accagcagct cccaggaaca
      241 gctcccaaac tcctcatcta ttatagtgat caacgagcct caggtgtctc tgaccgattc
      301 tctggctctc agtctggcac gtcagcctcc ctggccatca gtgggctcca ggccgaggat
      361 gaggctgatt attactgcgc agcatgggat gatagtctga gcggttacat cttcggtgct
      421 gggacccggc tcgccgtcgt aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01001531             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:22657:16878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001531
VERSION     KCWK01001531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22657:16878"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..444
                     /note="immunoglobulin light chain variable region"
     V_region        123..444
     V_segment       123..408
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67269.1"
                     /translation="DYYCQVWDSSSEWVF"
     J_segment       409..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           98 a          147 c          142 g           95 t
ORIGIN      
        1 acatgggatc aacgcagagt acatggggct gggtctcagg aggcagcatt gacggtgcct
       61 cagccatggc ctggaccctt ctcctcctcg gcctcctcgc ttactgcaca gactctgcga
      121 cctcctatga gttgactcag gcaccctcag tgtcagcggc ctcaggacag acggccagga
      181 tcacctgtgg gggagacaac attggaagta aaactgtgca ctggtaccaa cagaaggcag
      241 cgcaggcccc tgtgctggtc atctttgctg atagcaaacg gccctcaggg atccctgacc
      301 gattctctgg ctccaactca gggaacaccg ccaccctgac catcagcggg gtcgaggccg
      361 gggatgaggc tgactattac tgtcaggtgt gggacagtag tagtgaatgg gttttcggcg
      421 gagggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001532             323 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:11369:13213
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001532
VERSION     KCWK01001532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 323)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:11369:13213"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..283
                     /note="immunoglobulin light chain variable region"
     V_region        8..283
     V_segment       8..253
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67270.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       254..283
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>323
                     /gene="IGLC"
BASE COUNT           71 a          100 c           91 g           61 t
ORIGIN      
        1 acatgggggg acagacagtc aggattacct gccaaggaga cagcctcaga agctcttatg
       61 caagctggta ccaacagagg ccaggccagg cccctgtgct ggtcgtctat ggtaacaact
      121 accggccctc agggatccca gagcgattct ctggctccta ctcacgaaac acagcttcct
      181 tgaccatctc tggggctcag gtggaagatg aggctgacta ttactgtgac tcctgggaca
      241 gcagcggaac ccaattcgga ggagggaccc ggctgaccgt cctgggtcag cccaaggctg
      301 ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001533             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11902:14066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001533
VERSION     KCWK01001533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11902:14066"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67271.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          143 c          132 g           92 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgaac tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacgacat
      181 tggaactaaa actgtacact ggtaccagca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgat agtaaacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001534             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:4744:6081
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001534
VERSION     KCWK01001534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4744:6081"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67272.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          163 c          115 g          108 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcccctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctctgcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcagactca gatatggacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcctcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctactactgt gccattgggc acagcagcgg tgattacatc ttcgctgctg
      421 ggacccgcct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001535             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:20321:13747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001535
VERSION     KCWK01001535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20321:13747"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..260
                     /note="immunoglobulin light chain variable region"
     V_region        5..260
     V_segment       5..223
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <185..>232
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67273.1"
                     /translation="DYHCQVWDLNSHHLLF"
     J_segment       225..260
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>298
                     /gene="IGLC"
BASE COUNT           61 a           85 c           90 g           62 t
ORIGIN      
        1 acatggggac aacattggga gtgaagttgt gaactggtac cagcagaagc caccgcaggc
       61 ccctgtgttg gtcatctatg ctgatagcga gcggccctca gggatccctg aacggttctc
      121 tggctccaaa tcagggaaca cggccaccct gaccatcagc ggggtcgagg ccggggatga
      181 ggctgactat cactgtcagg tgtgggacct taatagtcat catttgttat tcggaggagg
      241 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001536             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:20239:19123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001536
VERSION     KCWK01001536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20239:19123"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..431
                     /note="immunoglobulin light chain variable region"
     V_region        110..431
     V_segment       110..395
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67274.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       399..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           92 a          146 c          135 g           96 t
ORIGIN      
        1 acatgggggc cctgtctggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggcc tcctcgctta ctgcacaggc tctgcgacct cctatgaatt
      121 gactcagtca ccctcagtgt cagcggcctc aggacagccg gccaggatca cctgtggggg
      181 agacaacatt ggaactaaaa ctgtgcactg gtaccaacag aagccaccgc agggccctgt
      241 attggtcatc tttggtgata gtagacggcc ctcagggatc cctgagcgct tctctggctc
      301 caactcaggg aacaccgcca ccctgaccat cagcagggtc gaggccgggg atgaggctga
      361 ctattactgt caggtgtggg acagtagtag taaatggata ttcggcgggg ggacccggct
      421 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001537             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:8249:8578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001537
VERSION     KCWK01001537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8249:8578"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67275.1"
                     /translation="DYYCQVWDNSNKYAIF"
     J_segment       399..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          145 c          135 g           96 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgc ggcctcctat ggattgactc
      121 agccacgctc agtgtccgtg tccccgggac agacggccag gatcacctgt gggggagaca
      181 agattggaag taaaagtgta cactggtacc agcagaggcc accgcaggcc cctgtactgg
      241 tcatctatgt tgatggcgac cggccctcag ggatccctga acgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag tctgactatt
      361 actgtcaggt atgggataat agtaataaat acgcgatctt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001538             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:26117:5320
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001538
VERSION     KCWK01001538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:26117:5320"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    70..400
                     /note="immunoglobulin light chain variable region"
     V_region        70..400
     V_segment       70..363
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>372
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67276.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       364..400
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        401..>438
                     /gene="IGLC"
BASE COUNT           81 a          140 c          111 g          106 t
ORIGIN      
        1 acatggggct ccttttgtct cttgtcaatc accatgtctg tgtctctctg acttccaggg
       61 tcctgggccc agtctgtgct gactcagcct ccctcagcgt ctgaggccgc caggaagagt
      121 gtcaccatct cctgttctgg aagcagctcc aacatcggaa ggaatagtgt atcctggtac
      181 cagcagctcc caggaacagc tcccaaactc ctcatctatt atagtgatca acgagcctca
      241 ggtgtctctg gccgattctc tggctccaag tctggcacgt cagcctccct ggccatcagc
      301 gggctccaga ccgaggatga ggctgattat tactgcgcag catgggatga tagcctgagc
      361 ggttacatct tcggtgctgg gacccggctc accgtcctag gtcagcccaa ggcttccccc
      421 acggtcactc tgttcccg
//
LOCUS       KCWK01001539             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:5268:12634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001539
VERSION     KCWK01001539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5268:12634"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67277.1"
                     /translation="DYYCQVYDSSANVVF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          161 c          127 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaag atgtactggt accagcagaa ggcagggagc gctcccaggt
      241 tatacctcta ctacgactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaggtaaca cagccttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtggtattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001540             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:13216:10806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001540
VERSION     KCWK01001540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13216:10806"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67278.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          148 c          132 g           98 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctccgatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt aagagtgtgc actggtacca gcacaagcca ccgcaggccc ctatcctggt
      241 catctattat tataccgaac ggccctcggc gatccctgag cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacacta ctattgatca tggctttttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001541             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:20058:6738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001541
VERSION     KCWK01001541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20058:6738"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67279.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          156 c          123 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatt
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgataggc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001542             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:18029:17786
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001542
VERSION     KCWK01001542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18029:17786"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67280.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       412..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          155 c          122 g          110 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc tccttctcac tctgctggtt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagc atctggggcc cccggacaga gggtcaccat ctcctgcatt
      181 agcagcagct ccaacatcgg ggcggcttat tatgtatcct ggtaccaaca gttaccagga
      241 acagccccca aactcctcat ctttgaaaat aataagcgac cctcaggggt ttctgaccga
      301 ttctctggct ccaagtctgg tccctcagcc tccctgacca tcactggact ccaatctgag
      361 gatgaggctg attattactg tttagcatgg gataccagcc tgaattggat cttcggcgga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001543             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:15970:15890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001543
VERSION     KCWK01001543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:15970:15890"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..404
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67281.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          157 c          123 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatccacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagtagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001544             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:6899:12742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001544
VERSION     KCWK01001544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:6899:12742"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..401
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67282.1"
                     /translation="DYYCQSHDTSSVFF"
     J_segment       402..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           82 a          163 c          126 g          105 t
ORIGIN      
        1 acatggggcc tggctgtggc tcaggaagca gagcctggag catctccacc atggcctggg
       61 ctccactcct cctcaccctc ctcgctcact gcacagggtc ttgggctgag gttgtgttca
      121 ctcagcccca ttctgtgtcg gggtctccgg ggcagacggt caccatctcc tgcacccgca
      181 gcagtggcag cattgacaac agttttgtgt actggtacca gcagcggccg ggcagcgccc
      241 ccaccactgt gatttacgca gataaccaaa gaccctctgg ggtccctgat cggttctctg
      301 gctccatcga cagctcctcc aactctgcct ccctcaccat ctctggactg aagtctgagg
      361 acgaggctga ctactactgt cagtctcatg acaccagcag tgtgtttttc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001545             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:10012:5092
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001545
VERSION     KCWK01001545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10012:5092"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67283.1"
                     /translation="DYYCQVYDGSANIIF"
     J_segment       413..447
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          167 c          118 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgagctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttga tactaaaaac atctactggt accagcagag gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tccggtaata cagccttttt gttcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tctatgacgg tagtgctaat atcatcttcg
      421 gtgctgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt
      481 tcccg
//
LOCUS       KCWK01001546             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:7003:17132
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001546
VERSION     KCWK01001546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7003:17132"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67284.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          147 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtacact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttgttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001547             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:28438:9151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001547
VERSION     KCWK01001547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:28438:9151"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..296
                     /note="immunoglobulin light chain variable region"
     V_region        8..296
     V_segment       8..259
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <221..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67285.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       261..296
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>334
                     /gene="IGLC"
BASE COUNT           69 a          105 c           86 g           74 t
ORIGIN      
        1 acatgggggg cagagggtca ccatctcctg cactgggagc agctccaaca ttggaggtta
       61 ttatatatcc tggtaccagc agctcccagg aacggccccc aaactcctcg tctatgacaa
      121 taataagcga ccctcagggg tttctgaccg attctctggc tccaagtctg gttcctcagc
      181 caccctgacc atcactgggc tccagactga ggatgaggct gattattact gccagtccta
      241 tgacagcagt ctgagtgctc gggtattcgg cggagggacc cggctaaccg tcctaggtca
      301 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001548             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12689:4948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001548
VERSION     KCWK01001548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12689:4948"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    77..425
                     /note="immunoglobulin light chain variable region"
     V_region        77..425
     V_segment       77..388
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67286.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          159 c          111 g          106 t
ORIGIN      
        1 acatggggcc gtgtccacca tggccctgac tcctctcctc ctcctgctcc tctctcactg
       61 cacaggttcc ctctcccagc ctgtgctgac tcagccaccc tccctgtctg catccccggg
      121 agcatcggcc agactcccct gcaccctgag cagtgacctc agtgttggtg gtaaaaacat
      181 gtactggtac cagcagaagc cagggcgcgc tcccaggttt ttcctgtact acaactccga
      241 ctcagacaag cagctgggac ctggggtccc caatcgagtc tctggctcca aggagacctc
      301 aagtaacaca gcgtttttgc tcatctctgg gctccagcct gaggacgagg ccgattatta
      361 ctgtcacgta tatgacagta gtactaatgt gttattcgga ggagggaccc gtctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001549             346 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:12712:14686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001549
VERSION     KCWK01001549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 346)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 346)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12712:14686"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..308
                     /note="immunoglobulin light chain variable region"
     V_region        5..308
     V_segment       5..272
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <239..>280
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67287.1"
                     /translation="DYYCAVWSSSAYIF"
     J_segment       273..308
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        309..>346
                     /gene="IGLC"
BASE COUNT           65 a          106 c           88 g           87 t
ORIGIN      
        1 acatggggca tcagtcagac tcacctgcac cttgcgcact ggcctcaatg ttggtggcta
       61 ctacatattc tggtaccagc agaagccagg gagtcctccc cggttccttc tgaattacta
      121 ctcagactca aatcagggcc agggctctgg agtccccagc cgcttctctg gatccaaaga
      181 tgtttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgagg atgaggctga
      241 ctattactgt gccgtttggt ccagcagcgc ttacatcttc ggtggtggga ctcggctcac
      301 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001550             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:12916:6400
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001550
VERSION     KCWK01001550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12916:6400"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67288.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       391..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          149 c          134 g           93 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctatgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa tatgtgcact ggtaccagca gaagccagcg caggcccctg tgttggtcat
      241 ctatgctgat accagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcaccggggt cgaggccggg tatgaggctg actatttctg
      361 tcaggtttgg gacgatagta gtgatcatcc ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001551             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:28176:9368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001551
VERSION     KCWK01001551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:28176:9368"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..274
                     /note="immunoglobulin light chain variable region"
     V_region        8..274
     V_segment       8..238
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>246
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67289.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       242..274
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        275..>312
                     /gene="IGLC"
BASE COUNT           69 a           87 c           93 g           63 t
ORIGIN      
        1 acatggggga tcacctgtgg gggagacaac attggaacta aaactgtgca ctggtaccaa
       61 cagaagccac cgcagggccc tgtattggtc atctttgctg atagtagacg gccctcaggg
      121 atccctgagc gattctctgg ctccaattca gggaacaccg ccaccctgac catcagcagg
      181 gtcgaggccg gggatgaggc tgactattac tgtcaggtgt gggacagtag tagtaaatgg
      241 atattcggcg gggggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      301 actctcttcc cg
//
LOCUS       KCWK01001552             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:12906:17579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001552
VERSION     KCWK01001552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12906:17579"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67290.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           84 a          162 c          123 g          111 t
ORIGIN      
        1 atgggggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggta gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgtact tctactccga ctcagacaag cagctgggac ctggggtccc cgatcgcgtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcaggtg tttgacagta gtgctgtctt attcggagga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001553             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:21651:19086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001553
VERSION     KCWK01001553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:21651:19086"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..418
                     /note="immunoglobulin light chain variable region"
     V_region        88..418
     V_segment       88..381
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <346..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67291.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       382..418
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>456
                     /gene="IGLC"
BASE COUNT           88 a          151 c          113 g          104 t
ORIGIN      
        1 acatgggggc actctcggga catctccacc atggcctggg atctgctcct cttcaccctc
       61 ctcactcagg gcacaggatc ctgggctcag gctgccctga ctcagcctcc ctcaatgtct
      121 gggtctcctg gacagtcggt caccatctcc tacactggaa ccagcagtga cattggtggt
      181 tataaccgtg tctcctggta ccaacagcac ccaggcaaag accccaaatt catgatttat
      241 gaggtcagtc aacggccctc aggggtctct gatcgtatct ctggctccaa gtctggcaac
      301 acggcctccc tgaccatctc tgggctccag actgaggatg aggctggtta ttactgcagc
      361 tcatttgcag gtaccaacac tggcttaatc ggtggaggga cccggctgac cgtcctaggt
      421 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001554             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:19562:15830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001554
VERSION     KCWK01001554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:19562:15830"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..406
                     /note="immunoglobulin light chain variable region"
     V_region        88..406
     V_segment       88..374
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67292.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       375..406
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           85 a          142 c          119 g           98 t
ORIGIN      
        1 tcagaagcag agctctgggg tgtctccacc atggcctgga ctcctctctg gctcaccctc
       61 ctcagtcttt gcacaggttc tctggtttct tctgacctga ctcaggaccc tgccgtgtct
      121 gtggccttgg gacagacagt caggattacc tgccaaggag acagcctcag aagctcttat
      181 gcaagctggt accagcagag gccaggccag gcccctgtgc tggtcgtcta tggtaacaac
      241 taccggccct cagggatccc agagcgattc tctggctcct actcacgaaa cacagcttcc
      301 ttgaccatct ctggggctca ggtggaagat gaggctgact attactgtga ctcctgggac
      361 agcagcggaa cccaattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct
      421 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001555             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:11092:16261
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001555
VERSION     KCWK01001555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:11092:16261"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67293.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           88 a          163 c          111 g          112 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttga gcagtggcac caatgttggt
      181 agttacagca ttttctggta ccagcagaag ccagggagtc ctccccggta ccttctctac
      241 tactactcag actcaactaa gcaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagccaatgc agggctttta ctgatctctg ggctccagtc tgaggatgag
      361 gctgactatt actgtgccat ttggcacagc agcgcttctt gcatcttcgg tcctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001556             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:19082:21230
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001556
VERSION     KCWK01001556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19082:21230"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67294.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          156 c          126 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca agtcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgaggggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcaa cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001557             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:23389:14485
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001557
VERSION     KCWK01001557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23389:14485"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..246
                     /note="immunoglobulin light chain variable region"
     V_region        4..246
     V_segment       4..212
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>220
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67295.1"
                     /translation="DYYCCSRSSSSTYVF"
     J_segment       213..246
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        247..>286
                     /gene="IGLC"
BASE COUNT           53 a           94 c           68 g           71 t
ORIGIN      
        1 acatgggggt tataactctg tctcctggta ccaacaacac ccaggcaaag cccccaaagt
       61 catgattttt ggtgtcaata atcggccctc tggggtctct gaccgcttct ctggctccaa
      121 gtctggcaac acggcctccc tgaccatctc tgggctccag tctgaggacg aggctgatta
      181 ttactgttgt tcacgttcaa gcagcagcac ttacgtcttc ggtcctggga cccggctcac
      241 cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001558             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:16817:3789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001558
VERSION     KCWK01001558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16817:3789"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67296.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          142 c          141 g           92 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttggaagtga agttgtgaac tggtaccaga agaagccagc gcaggcccct gcactggtca
      241 tctatgctga tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagggggg tcgaggccgg gggtgaggct gactattact
      361 gtcaggtgtg ggacatgcgt agtgatcaac cgctattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001559             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:14533:16507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001559
VERSION     KCWK01001559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14533:16507"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67297.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       405..439
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           91 a          159 c          113 g          114 t
ORIGIN      
        1 atggggactg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgacccagcc aacctccctc
      121 tcagcatctc cgggagcatc agtcagactc agctgcacct tgagcagtgg catcaatgtt
      181 ggttcttaca ccatattctg gtaccagcag aagccaggga gtcctccccg gttccttctg
      241 tactactact cagactcaaa taatcaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcagccaa tgcagggctt ttactgatct ctgggctcca gtctgaagat
      361 gaggctgact attactgtgc catgtggcac agcagcgctt atgccttatt cggaggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001560             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:6722:4282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001560
VERSION     KCWK01001560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:6722:4282"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67298.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca aacagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001561             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:6569:14736
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001561
VERSION     KCWK01001561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:6569:14736"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67299.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          162 c          119 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca tcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001562             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:22094:22327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001562
VERSION     KCWK01001562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22094:22327"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67300.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          155 c          117 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggaacatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catatactgg taccaccaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacaca gcagcggtga ttatatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001563             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:25908:14746
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001563
VERSION     KCWK01001563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:25908:14746"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..411
                     /note="immunoglobulin light chain variable region"
     V_region        63..411
     V_segment       63..374
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67301.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           84 a          155 c          100 g          110 t
ORIGIN      
        1 acatgggggc ctggactcct ctcctcctcc tgctcctctc tcactgcaca ggttccctct
       61 cccagcctgt gctgacccag ccaacctccc tctcagcatc tccgggagca tcagccagac
      121 tcagctgcac ctttagcagt ggcatcaatg ttggtagtta cagcatattc tggtaccagc
      181 agaagccagg gagtcctccc cggtaccttc tctactacta ctcagactca agtaaacacc
      241 agggctctgg agtccccagc cgcttctctg gatccaagga tgcttcggcc aatgcaggcc
      301 ttttactgat ctctgggctc cagtctgaag atgaggctga ctattactgt gccatatggc
      361 acagcagcgc ttcttatttc ttcggtactg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001564             342 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:14469:4355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001564
VERSION     KCWK01001564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 342)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14469:4355"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..304
                     /note="immunoglobulin light chain variable region"
     V_region        7..304
     V_segment       7..267
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <229..>276
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67302.1"
                     /translation="DYYCAVWDNSLTSPLF"
     J_segment       274..304
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        305..>342
                     /gene="IGLC"
BASE COUNT           71 a          108 c           84 g           79 t
ORIGIN      
        1 acatggggga ctcccgggca gagtgtcacc atctcttgct ctggaagcaa ctccaacatt
       61 ggaaataatt atgtatactg gtaccagcac ctcccaggaa cggcccccaa gctcctcatc
      121 tattatagtt atcagcgacc ctcaggggtc cctgaccgat tctctggctc taagtctggc
      181 acctcagcct ccctggccat cactggtctc cgaactgagg atgaggctga ttattactgt
      241 gcagtatggg ataacagcct gaccagtccg ttgttcggag gagggacccg gctgaccgtc
      301 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001565             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:22025:2802
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001565
VERSION     KCWK01001565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22025:2802"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67303.1"
                     /translation="DYYCQVYDSSDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          159 c          124 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagag gccagggagc gctcccaggt
      241 tattcctgta ttactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaggtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgatgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001566             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:26477:10941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001566
VERSION     KCWK01001566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:26477:10941"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..388
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67304.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          148 c          119 g          109 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtttctg gggcgcccgg gcagagggtc acgatctcct gcagtgggag caactccaac
      181 attggatatt attatgtgca gtggtaccag cagcttccag gaacggcccc caaactcctc
      241 atctatgaaa ataataagcg accctctggg gtttctgatc gattctctgg ctcccagtct
      301 ggtacctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgccactcct atgacagcag tttgagtggt gtcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001567             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:10787:12360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001567
VERSION     KCWK01001567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:10787:12360"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67305.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          136 c          122 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgtac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001568             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:24889:12960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001568
VERSION     KCWK01001568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24889:12960"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67306.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           96 a          137 c          128 g          103 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccatcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagata
      181 cattgccaaa aaaatatgct tattggttcc agcggaagcc aggccagtcc cctgtgttga
      241 tcatctatga ggacaacaaa cggtcttctg ggatcgctga gagattctct ggctccagct
      301 cagggacagt ggccaccttg agtatcagtg gggcccaggt ggaggatgaa gctgactact
      361 actgttactc agcagacagc agtggtaatg gcttattcgg aggagggacc cgactgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001569             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:22711:17835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001569
VERSION     KCWK01001569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22711:17835"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67307.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       396..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           87 a          141 c          138 g          102 t
ORIGIN      
        1 acatggggga gcctgacttt gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgctcacttt acaggctctg tggcctccta tgagttgcct
      121 cagccacgct cagtgtccgt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aacattggaa gtaatagtgt gcattggtac cagcagaagc caccgcgggc ccctgtattg
      241 gtcatctctg ttgatagcga acggccctca gggatccctg agcgattctc tggttccaga
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggataa tatttataaa tacgcggtat tcggcggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001570             346 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:21875:6430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001570
VERSION     KCWK01001570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 346)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 346)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21875:6430"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..308
                     /note="immunoglobulin light chain variable region"
     V_region        7..308
     V_segment       7..271
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <233..>280
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67308.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       272..308
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        309..>346
                     /gene="IGLC"
BASE COUNT           66 a          107 c           91 g           82 t
ORIGIN      
        1 acatgggtct gaggccgcca ggaagagtgt ctccatctcc tgttctggaa gcagctccaa
       61 catcggaagt catagtgtct cctggtacca gcagttccca ggaacagctc ccaaactcct
      121 catctattat agtgatcaac gagcctcagg tgtctctgac cgattctctg gctctcagtc
      181 tggcacgtca gcctccctgg ccatcagtgg gctccaggcc gaggatgagg ctgattatta
      241 ctgcgcagca tgggatgata gtctgagcgg ttacatcttc ggtgctggga cccggctcgc
      301 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001571             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:9307:12475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001571
VERSION     KCWK01001571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9307:12475"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67309.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       408..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           90 a          152 c          126 g          112 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcacgat ctcctgcagt
      181 gggagcaact ccaacattgg atattattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccaaac tcctcatcta tgaaaataat aagcgaccct ctggggtttc tgatcgattc
      301 tctggctccc agtctggtac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca ctcctatgac agcagtttga gtggtgtctt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001572             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:3424:12120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001572
VERSION     KCWK01001572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:3424:12120"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..282
                     /note="immunoglobulin light chain variable region"
     V_region        7..282
     V_segment       7..242
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <210..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67310.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       245..282
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>320
                     /gene="IGLC"
BASE COUNT           66 a           95 c           87 g           72 t
ORIGIN      
        1 acatgggcgg tggcatcaat gttcttggct accacataca ctggtaccag cagaagccag
       61 ggagtcctcc ccggtatctt ctgagataca aatcggactc agataagggc cagggctctg
      121 gagtccccag ccgcttctct ggatccaaag atgcttcagc gaacgcaggg attttacgca
      181 tctctgggct ccagtctgag gatgaggctg actattactg tgccattggg cacagcagcg
      241 gtgattacat cttcggtgct gggacccggc tcaccgtcct aggtcagccc aaggcttccc
      301 ccacggtcac tctgttcccg
//
LOCUS       KCWK01001573             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:16811:9196
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001573
VERSION     KCWK01001573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16811:9196"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..436
                     /note="immunoglobulin light chain variable region"
     V_region        90..436
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67311.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           91 a          161 c          110 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt tagtagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc ggtactggga
      421 cccggctcac cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001574             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:14447:3675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001574
VERSION     KCWK01001574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14447:3675"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..294
                     /note="immunoglobulin light chain variable region"
     V_region        8..294
     V_segment       8..260
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67312.1"
                     /translation="DYYCQVWGMTSDHPVF"
     J_segment       263..294
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>335
                     /gene="IGLC"
BASE COUNT           69 a           98 c          107 g           61 t
ORIGIN      
        1 acatggggtc cccaggacag acggccagga tcacctgtgg gggagacaac attggaagtg
       61 aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgctggtc atctctggtg
      121 atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca gggaacacgg
      181 ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac tgtcaggtgt
      241 ggggcatgac tagtgatcat ccggtattcg gcggagggac ccggctaacc gtccaaggtc
      301 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001575             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:24447:17367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001575
VERSION     KCWK01001575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24447:17367"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67313.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       414..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           93 a          161 c          125 g          108 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctcg tctcctctcc tcctcaccct tttcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acacagccgc cctcagtgtc tggggcccca gggcagaggg tcaccatctc
      181 ctgcactggg agcagctcca acattggagg ttattatata tcctggtacc agcagctccc
      241 aggaacggcc cccaaactcc tcgtctatga caataataag cgaccctcag gggtttctga
      301 ccgattctct ggctccaagt ctggttcctc agccaccctg accatcactg ggctccagac
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agtctgagtg ctcgggtatt
      421 cggcggaggg acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01001576             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:13365:13665
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001576
VERSION     KCWK01001576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13365:13665"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67314.1"
                     /translation="DYYCAAWDDRLTGYVF"
     J_segment       415..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          158 c          124 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cgggagcaat agtgtatcct ggtaccagct actcccagaa
      241 acggctccca aactcctcat ctattataat aatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatcgcc tgaccggtta cgtattcggt
      421 gttgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001577             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:11036:7238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001577
VERSION     KCWK01001577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:11036:7238"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67315.1"
                     /translation="DYYCAMWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          163 c          110 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001578             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:19039:17044
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001578
VERSION     KCWK01001578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19039:17044"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67316.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          154 c          120 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgactattac tgcagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001579             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:13765:13473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001579
VERSION     KCWK01001579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13765:13473"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..443
                     /note="immunoglobulin light chain variable region"
     V_region        92..443
     V_segment       92..406
                     /gene="IGLV5-107"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67317.1"
                     /translation="DYYCCTWHGSSKTQIF"
     J_segment       411..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           88 a          159 c          119 g          115 t
ORIGIN      
        1 acatgggggg tagggctcag gggctctgtc caccatggcc tggactcttc tccttctcat
       61 gctcctctct cactgcacag gttccctctc ccagcctgtg ctgactcagc catcttccca
      121 ttccgcatct cctggagcgc cagccagact cacctgcacg ctgagcagtg gcttcagtgt
      181 tggtgacttc tggatacggt ggtaccaaca aaagccaggg agccctcccc ggtatctcct
      241 gtactaccac tcagactcag ataaccaccg aggctctgga gttcccagcc gcttctctgg
      301 atccaatgat gcatcagcca atgcagggat tctctttatc tctgggctcc agcctgagga
      361 tgaggctgac tattactgtt gtacatggca tggcagctct aagactcaga tattcggcgg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01001580             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:23083:20224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001580
VERSION     KCWK01001580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23083:20224"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67318.1"
                     /translation="VYYCAIGHSSGLYIF"
     J_segment       402..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           87 a          156 c          121 g          113 t
ORIGIN      
        1 acatgggggg tggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc aagcctatgc tgactcagcc ggcctccctc
      121 tcagcatctc ctggagcatc agccagtctc acatgcacct tcagcggtgg catcaatgtt
      181 gctgtctacc acgtacactg gtaccagcag aagccaggga gtcccccccg gtatcttctg
      241 aggtacaaat cagactcaga taagggccag ggctctgggg tccccagccg cttctctgga
      301 tccagtaatg cttcagtgaa cacagggatt ttacgcattt ctgggctcca gtctgaggat
      361 gaggctgtct attactgtgc cattgggcac agcagcggtc tttacatctt cggtgctggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01001581             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:7029:12963
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001581
VERSION     KCWK01001581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:7029:12963"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..434
                     /note="immunoglobulin light chain variable region"
     V_region        90..434
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67319.1"
                     /translation="DYYCAIGHNSGDYIF"
     J_segment       401..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>476
                     /gene="IGLC"
BASE COUNT           95 a          152 c          117 g          112 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgtatacca catacactgg taccagcaga agccagggag tcccccccgg tttcttctga
      241 ggtacaaatc agattcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatttc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca atagcggtga ttacatcttc ggtgctggga
      421 cccgactcac cgtcataggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001582             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:27525:7607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001582
VERSION     KCWK01001582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:27525:7607"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67320.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          152 c          120 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg acccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001583             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:21207:14544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001583
VERSION     KCWK01001583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21207:14544"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..439
                     /note="immunoglobulin light chain variable region"
     V_region        93..439
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67321.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>479
                     /gene="IGLC"
BASE COUNT           91 a          164 c          110 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggttccg
      421 ggacccggct caccgtcctg ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001584             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:26936:14307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001584
VERSION     KCWK01001584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:26936:14307"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67322.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          154 c          111 g          117 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcttc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttgctaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001585             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:24214:17810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001585
VERSION     KCWK01001585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:24214:17810"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67323.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           97 a          147 c          128 g           90 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga actcctatga cctgactcag
      121 ccaccctcag tgtcagcggc ctcaggacag acggccagga tcacctgtgg cggagacaac
      181 attggaatta aaaatgtaca ctggtaccac cagaagccag cgcaggcccc tgtgctggtc
      241 atctatgctg ataacaaacg gccctcaggg atccctgagc gattctctgc ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg gtattcggcg gagggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001586             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:23728:16735
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001586
VERSION     KCWK01001586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:23728:16735"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..297
                     /note="immunoglobulin light chain variable region"
     V_region        8..297
     V_segment       8..260
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67324.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       261..297
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>335
                     /gene="IGLC"
BASE COUNT           75 a          100 c           89 g           71 t
ORIGIN      
        1 acatgggggc cttgggacaa acagtcagga tgacctgcca aggagacagc ctcaaaacct
       61 attatgcaag ctggtaccag cagaagccag gccaggtccc tgtgctggtc atctatggta
      121 acaactaccg gccctcaggg atcccaggcc gattctctgt ctcctggtca ggaaacacag
      181 gttccttgac catcactgcg gctcaggtgg aagatgaggc tgactattac tgtaagtcct
      241 gggacagcag tggtacccat tacatcttcg gtgctgggat ccggctcacc gtcctaggtc
      301 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001587             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:24306:22145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001587
VERSION     KCWK01001587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:24306:22145"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67325.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          107 a          137 c          121 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggctgac ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg acctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagaagtca ggccagggcc ctagactggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagcgg ggcccagaca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagaa gtcctaatca tgtgtttttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001588             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:20086:17129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001588
VERSION     KCWK01001588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:20086:17129"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67326.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          140 c          137 g          101 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 cgccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtaga ggagacaaca
      181 ttggaagtga agttgtcaac tggtaccagc agaggccacc gcaggcccct gtggtggtca
      241 tctatgctga ttatgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcggag tcgaggccgg ggatgaggct gactattatt
      361 gtcaggtgtg ggacatttat attgaccatc cggtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001589             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:23370:3887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001589
VERSION     KCWK01001589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:23370:3887"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67327.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          162 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tacatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001590             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:15424:6799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001590
VERSION     KCWK01001590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15424:6799"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..264
                     /note="immunoglobulin light chain variable region"
     V_region        8..264
     V_segment       8..230
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <192..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67328.1"
                     /translation="DYYCSSYEGTNSFIF"
     J_segment       231..264
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>302
                     /gene="IGLC"
BASE COUNT           64 a           93 c           74 g           71 t
ORIGIN      
        1 acatgggcag cagtgacatc ggtggttata actatgtctc ctggtaccag cagcacccag
       61 gcaaagcccc caaactcatg atttatgatg tcagtaagcg gccctcaggg gtctctgatc
      121 gcttctctgg ctccaaatct ggcaacacgg cctccctgac catctctggg ctccaggctg
      181 aggatgaggc tgattattac tgcagctcat atgaaggcac caacagtttc atcttcggtg
      241 ttgggacccg gctcaccgta ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      301 cg
//
LOCUS       KCWK01001591             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:8766:4437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001591
VERSION     KCWK01001591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8766:4437"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..413
                     /note="immunoglobulin light chain variable region"
     V_region        88..413
     V_segment       88..397
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67329.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       402..413
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>439
                     /gene="IGLC"
BASE COUNT           84 a          146 c          100 g          109 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagt cagactcagc tgcaccttga gcagtggcat caatgttggt
      181 tcttacacca tattctggta ccagcagaag ccagggagtc ctccccggtt ccttctgtac
      241 tactactcag actcaaataa tcaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagccaatgc agggctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccat gtggcacagc agcgcttatg ccttattcgg aggctgcccc
      421 ctcggtcact ctcttcccg
//
LOCUS       KCWK01001592             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:13853:21299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001592
VERSION     KCWK01001592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:13853:21299"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    193..336
                     /note="immunoglobulin light chain variable region"
     V_region        193..336
     V_segment       193..299
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <267..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67330.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       306..336
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           59 a          139 c           94 g           82 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtggtgac tcagtcgtcc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cggtgggcac
      181 agcgactaca ccatcgcttc tccggctcca gctccggggc tgagcgctac ctcaccatct
      241 ccaacctcca gtctgaggat gaggctgatt attactgtca gacctgggag actggcattc
      301 aggtgttcgg cggagggacc cggctaaccg tcctaggtca gcccaaggct gccccctcgg
      361 tcactctctt cccg
//
LOCUS       KCWK01001593             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:18899:10358
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001593
VERSION     KCWK01001593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18899:10358"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67331.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          150 c          137 g           94 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaac taaatatgtg cactggtacc agcagaagcc agcgcaggcc cctgtgttgg
      241 tcatctatgc tgataccaga cggccctcag ggatccctga gcgattctct ggctccaact
      301 ccgggaacac cgccaccctg accatcagcg gggtcgaggc cgggtatgag gctgactatt
      361 tctgtcaggt gtgggacgat agtagtgatc atccggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001594             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:11136:14254
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001594
VERSION     KCWK01001594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11136:14254"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67332.1"
                     /translation="DYYCQVYDSNAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          164 c          118 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctttcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg cagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctcta ctactactcc gactcagaca accaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgccagg tgtatgacag taatgctgtt ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001595             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:18270:19836
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001595
VERSION     KCWK01001595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18270:19836"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..226
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67333.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       227..263
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           60 a           94 c           78 g           69 t
ORIGIN      
        1 acatgggagc tccaacatcg gaagtcatag tgtctcctgg taccagcaag tcccaggaac
       61 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      121 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      181 tgaggctgat tattactgcg cagcatggga tgatagcctg aggggttaca tcttcggtgc
      241 tgggacccgg ctcgccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      301 g
//
LOCUS       KCWK01001596             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:10819:23524
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001596
VERSION     KCWK01001596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10819:23524"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..429
                     /note="immunoglobulin light chain variable region"
     V_region        111..429
     V_segment       111..397
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67334.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       398..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           92 a          145 c          129 g          101 t
ORIGIN      
        1 acatggggcc cttagctgtg ggctcagaag cagagctctg gggtgtctcc accatggcct
       61 ggactcctct ctggctcacc ctcctcagtc tttgcacagg ttctatggtt tcttctgagc
      121 tgactcagga ccctgcagtg tctgtggcct tgggacagac agtcaggatt acctgccaag
      181 gagacagcct cagaagctct tatgcaagct ggtaccaaca gaggccaggc caggcccctg
      241 tgctggtcgt ctatggtaac agcaaccggc cctcagggat cccagagcga ttctctggct
      301 cctactcacg aaacacagct tccttgacca tcactggggc tcaggtggaa gatgaggctg
      361 actattactg tgactcctgg gacagcagcg gaacccaatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001597             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:16123:15026
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001597
VERSION     KCWK01001597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16123:15026"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67335.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          163 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagcctc
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagaca tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001598             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:14903:6877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001598
VERSION     KCWK01001598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:14903:6877"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67336.1"
                     /translation="DYYCAAWDDRLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           93 a          157 c          125 g          106 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagaaatgg tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agcgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatcgcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01001599             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:9448:13541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001599
VERSION     KCWK01001599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9448:13541"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67337.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       405..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           85 a          153 c          131 g          111 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc tccttctcac tctgctggtt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagc atctggggcc cccgggcaga gggttaccat ctcctgcact
      181 gggagcagct ccaacatcgg ggcgggtttt tatgtgtcct ggtaccagca gttccctgga
      241 acagccccca aactcctcat ctttgaaaat aataagcgac cctcaggggt ttctgaccga
      301 ttctctggct ccaagtctgg ttcctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ctcatcatgg gagagcagcc tgaattgggt attcggcgga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001600             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:7340:20066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001600
VERSION     KCWK01001600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7340:20066"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67338.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          161 c          123 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgttg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001601             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:18409:13910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001601
VERSION     KCWK01001601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18409:13910"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67339.1"
                     /translation="DYCCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          160 c          125 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagag gccagggagc gctcccaggt
      241 tattcctgta ttactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaggtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tgctgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001602             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:9787:4044
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001602
VERSION     KCWK01001602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:9787:4044"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67340.1"
                     /translation="DYYCSSYAGFNTLVF"
     J_segment       404..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          156 c          122 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtagttata accgtgtctc ctggtaccaa catcacccag acaaagcccc
      241 caaagtcgtg atttatgagg gcagtcagcg gccctcaggg gtctctgatc gcttctctgc
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggctt caatactttg gttttcggcg gagggacccg
      421 gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001603             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:11367:14048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001603
VERSION     KCWK01001603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11367:14048"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67341.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           90 a          156 c          128 g          110 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aagagtgtct ccatctcctg
      181 ttctggaagc agctccaaca tcggaagtca tagtgtctcc tggtaccagc aagtcccagg
      241 aacagctccc aaactcctca tctattatag tgatcaacga gcctcaggtg tctctgaccg
      301 attctctggc tctcagtctg gcacgtcagc ctccctggcc atcagtgggc tccagaccga
      361 ggatgaggct gattattact gcgcagcatg ggatgatagc ctgaggggtt acatcttcgg
      421 tgctgggacc cggctcgccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01001604             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:12639:5635
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001604
VERSION     KCWK01001604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12639:5635"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67342.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       399..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           82 a          164 c          113 g          113 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccac
      181 cagtgacgtt ggtggttcta actctgtctc ctggtaccaa caacacccag gcaaagcccc
      241 caaactcatg atttttggtg tcaataatcg gccctctggg gtctctgacc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagtctg aggacgaggc
      361 tgattattac tgttgttcac attcaaccag tagcacttac gtcttcggtc ctgggacccg
      421 gctcaccgtc ctgggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01001605             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:12557:12305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001605
VERSION     KCWK01001605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12557:12305"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67343.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           88 a          143 c          127 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 ggcagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001606             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:13947:12541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001606
VERSION     KCWK01001606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13947:12541"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67344.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           90 a          155 c          126 g          110 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcaag tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg aggggttaca tcttcggtgc
      421 tgggacccgg ctcgccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01001607             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:10202:9828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001607
VERSION     KCWK01001607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:10202:9828"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67345.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          157 c          127 g          106 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaaggaat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctggccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagcgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001608             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:19176:20091
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001608
VERSION     KCWK01001608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19176:20091"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67346.1"
                     /translation="DYYCAAWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          156 c          122 g          113 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcac catctcctgt
      181 tctggaagca gttccaacat cggaagtaat agtgtttcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgctgcatgg gatgatagcc tgaccggtta catattcggt
      421 tttgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001609             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:20899:9927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001609
VERSION     KCWK01001609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20899:9927"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..387
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67347.1"
                     /translation="DYYCQSADSSGNYPLF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT          105 a          134 c          123 g          103 t
ORIGIN      
        1 acatgggggt gtggttctag gaggaagagc tctgggtgtc tcaccatgac ctggaccact
       61 gttctgctcc cctttctcac tctctgcaca ggctctgagg cctcctatga gctgacacag
      121 ccaccctcag tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagcaata
      181 ctggcaaaaa aatatgctca gtggttccaa cagaagccag gccaggtccc tgtgttggtg
      241 atatataaag acaatgagag gccctcaggg atccctgagc gattctctag ttctagttca
      301 gggacaacac ttaccttgac catcactggg gcccaggcag aagatgaggc tgactattac
      361 tgtcaatcag cagacagcag tggtaattac ccgttgttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001610             365 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:24870:17591
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001610
VERSION     KCWK01001610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 365)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 365)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24870:17591"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    195..327
                     /note="immunoglobulin light chain variable region"
     V_region        195..327
     V_segment       195..291
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <255..>299
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67348.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       292..327
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        328..>365
                     /gene="IGLC"
BASE COUNT           76 a          110 c          107 g           72 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgagc tgactcaggc
      121 accctcagtg tcagcggcct caggacagac ggccaggatc acctgtggcg gagacaacat
      181 tggaattaaa aatgtccaac tcagggaata ttgccaccct gaccatcagc agggtcgagg
      241 ccggggatga ggcagactat tactgtcagg tgtgggacag tagtagtaaa tgggtattcg
      301 gcggagggac ccggctaacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      361 tcccg
//
LOCUS       KCWK01001611             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:6107:21013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001611
VERSION     KCWK01001611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:6107:21013"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67349.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       403..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           83 a          163 c          127 g           98 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtggt gactcagtcg
      121 tcctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcggtggg
      181 cacagcgact acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggtatttg
      241 atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctgc tcgcttctcc
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggagact ggcattcagg tgttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001612             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:3528:7729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001612
VERSION     KCWK01001612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:3528:7729"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67350.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          160 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagag gccagggagc gctcccaggt
      241 tattcctgta ttactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaggtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 ca
//
LOCUS       KCWK01001613             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:14827:10354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001613
VERSION     KCWK01001613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14827:10354"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67351.1"
                     /translation="DYYCSSYAGRNTHWLF"
     J_segment       410..440
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           88 a          160 c          122 g          108 t
ORIGIN      
        1 acatgggggg gggggtctca ggaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caactacacc caggcaaagc
      241 ccccaaactc atgatttatg atgtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctgacaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 gactgattat tactgcagct catatgcagg ccgcaacact cattggcttt tcggcggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001614             279 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:4574:17269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001614
VERSION     KCWK01001614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 279)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4574:17269"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..241
                     /note="immunoglobulin light chain variable region"
     V_region        9..241
     V_segment       9..203
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <166..>213
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67352.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       205..241
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        242..>279
                     /gene="IGLC"
BASE COUNT           56 a           88 c           77 g           58 t
ORIGIN      
        1 acatggggtg tacactggta ccagcacaag ccaccgcagg cccctgttct ggtcatcttt
       61 tattataccg aacggccctc aggaatccct gagcgattct ctggctccaa atcagggaac
      121 accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta ttactgtcag
      181 gtgtgggaca caactattga tcacggcttg ttcggaggag ggacccggct gaccgtccta
      241 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001615             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:16046:19484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001615
VERSION     KCWK01001615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16046:19484"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67353.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       388..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          138 c          140 g           96 t
ORIGIN      
        1 acatggggtg actttgggaa gcagccttgg cggtgcctca gccatggccg ggacccttct
       61 cctcctcggc ctccttgctc actttacagg ctctgcggcc tcctatgagg tgactcagcc
      121 acgctcagtg tccgtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaaa agtgtgcagt ggtaccagca gacgccaccg caggcccctg tactggtcat
      241 ttatggtgat agggaacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gatagcagta gtaaatatgt gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001616             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:12678:14539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001616
VERSION     KCWK01001616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12678:14539"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67354.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       401..435
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           89 a          156 c          120 g          108 t
ORIGIN      
        1 acatggggtg ggatctcacg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtggccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc cggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt gttcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001617             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14112:16801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001617
VERSION     KCWK01001617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14112:16801"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67355.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          162 c          113 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagttacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaaa tgcttcaacg aacgcaggca tttttcacat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001618             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:24789:14400
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001618
VERSION     KCWK01001618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24789:14400"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67356.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          150 c          115 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001619             401 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:16304:19934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001619
VERSION     KCWK01001619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 401)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16304:19934"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..362
                     /note="immunoglobulin light chain variable region"
     V_region        73..362
     V_segment       73..326
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <291..>335
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67357.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       327..362
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        363..>401
                     /gene="IGLC"
BASE COUNT           84 a          124 c          105 g           88 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacagtgtcc ccaggacaga cggccaagat cacctgctct ggagatgcac
      121 tgccaaaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtgttgatca
      181 tcgatgagga caccaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      241 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      301 gttactcagc agacagcagt ggttatggct tattcggagg agggacccgg ctgaccgtcc
      361 tacgtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001620             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:23750:6770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001620
VERSION     KCWK01001620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23750:6770"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67358.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          163 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gtctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001621             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:28187:12007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001621
VERSION     KCWK01001621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:28187:12007"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..297
                     /note="immunoglobulin light chain variable region"
     V_region        8..297
     V_segment       8..244
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67359.1"
                     /translation="DYFCQVWDLNSHHLLF"
     J_segment       263..297
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>335
                     /gene="IGLC"
BASE COUNT           66 a          101 c          104 g           64 t
ORIGIN      
        1 acatggggtc cccaggacag acggccaggc tgacctgcgg gggagacaac attggaagtg
       61 aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc atctatgctg
      121 acagcgcgcg gccctcaggg atccctgagc gattctctgg ctccaagtca gggaacacgg
      181 ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactatttc tgtcaggtgt
      241 gggaccttaa cagtcatcat ctcttattcg gaggagggac ccggctgacc gtcctaggtc
      301 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001622             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17102:11200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001622
VERSION     KCWK01001622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17102:11200"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..424
                     /note="immunoglobulin light chain variable region"
     V_region        101..424
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67360.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>463
                     /gene="IGLC"
BASE COUNT           92 a          146 c          128 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcaacggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttatttgga ggagggaccc ggctgaccgt
      421 cctaagtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001623             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:20613:9576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001623
VERSION     KCWK01001623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20613:9576"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67361.1"
                     /translation="DYYCQVWDNSNKYAIF"
     J_segment       397..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          142 c          135 g           98 t
ORIGIN      
        1 acatgggggc tgactttggg aagcagcctt ggcggtgcct cagccatggc cgggaccctt
       61 ctcctcctcg gcctccttgc tcactttaca ggctctgcgg cctcctatga attgactcag
      121 ccacgctcag tgtccgtgtc cccgggacag acggccagga tcacctgtgg gggagacaag
      181 attggaatta aaagtgtaca ctggtaccag cagaggccac cgcaggcccc tgtattggtc
      241 atctatgttg atggcgaccg gccctcaggg atccctgaac gattctctgg ttccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggataatag taataaatac gcgatcttcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001624             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:15884:21714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001624
VERSION     KCWK01001624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15884:21714"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67362.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          162 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcggg
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001625             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:23538:16381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001625
VERSION     KCWK01001625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23538:16381"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67363.1"
                     /translation="DYHCQVWDINSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          144 c          133 g          100 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gtctctgcgg cctcctatga tctgactcag
      121 ccaccctcga tttcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtgaa ctggtaccaa cagaagccac cgctggcccc tgtgttggtc
      241 atctatgctg atagcgaccg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaccacgg ccaccctgag catcagcggg gtcgaggccg gggatgaggc tgactatcac
      361 tgtcaggtgt gggacattaa tagccatcat ctgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001626             521 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:11459:18857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001626
VERSION     KCWK01001626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 521)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 521)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..521
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11459:18857"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    153..483
                     /note="immunoglobulin light chain variable region"
     V_region        153..483
     V_segment       153..444
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <411..>455
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67364.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       446..483
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        484..>521
                     /gene="IGLC"
BASE COUNT           99 a          164 c          138 g          120 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg gttcactgca cagaagcaga atcatgatgc
      121 ctgtgtctct cccacgtcca gggtcttggg cccagtctgt gctgacgcag ccgccctcag
      181 catctggggc ccccgggcag agggtcacca tctcctgcac tgggagcagc tccaacatcg
      241 gggcgggttt ttatgtatcc tggtaccagc agttcccagg aaaagccccc aagctcctca
      301 tctttgaaaa taacaagcga ccctcagggg tttctgaccg attctctggc tccaagtctg
      361 gttcctcagc ctccctgacc atcactggac tccaatctga ggatgaggct gattattatt
      421 gttcatcatg ggaaagcagc ctgaattggg tattcggcgg agggacccgg ctgaccgtcc
      481 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001627             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:12354:17808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001627
VERSION     KCWK01001627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12354:17808"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67365.1"
                     /translation="DYYCQVWDINSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          138 c          137 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcaggc
      121 accctcgaat tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattaata gtcatcatct gttattcgga ggggggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001628             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:14128:12464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001628
VERSION     KCWK01001628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14128:12464"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67366.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          107 a          137 c          121 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 aatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001629             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:17144:14611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001629
VERSION     KCWK01001629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17144:14611"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67367.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          148 c          128 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaaca gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001630             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:21085:16235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001630
VERSION     KCWK01001630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21085:16235"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..404
                     /note="immunoglobulin light chain variable region"
     V_region        87..404
     V_segment       87..370
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67368.1"
                     /translation="DYYCYSSDSNSKWLF"
     J_segment       376..404
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>446
                     /gene="IGLC"
BASE COUNT           97 a          139 c          114 g           96 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tagcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagatgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatata
      181 cttattggtt cccgcagaag gcaggccagc cccctatggt gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aaggtgacta ctactgttac tcatcagaca
      361 gcaatagtaa atggctattc gacggaggga cccggctgac cgtcgtaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001631             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:6415:15050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001631
VERSION     KCWK01001631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:6415:15050"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..418
                     /note="immunoglobulin light chain variable region"
     V_region        101..418
     V_segment       101..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67369.1"
                     /translation="DFYCYSSDSNSKWIF"
     J_segment       390..418
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>460
                     /gene="IGLC"
BASE COUNT           98 a          140 c          123 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatagcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgaga tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttcccgca gaaggcaggc cagcccccta tggtgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaaggtg acttctactg
      361 ttactcatca gacagcaata gtaaatggat attcgacgga gggacccggc tgaccgtcgt
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001632             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:16218:13425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001632
VERSION     KCWK01001632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16218:13425"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..406
                     /note="immunoglobulin light chain variable region"
     V_region        88..406
     V_segment       88..374
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67370.1"
                     /translation="DYYCDSWDSSGAQF"
     J_segment       375..406
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           88 a          140 c          119 g           97 t
ORIGIN      
        1 tcagaagcag agctctgggg tgtctccacc atggcctgga ctcctctctg gctcaccctc
       61 ctcagtcttt gcacaggttc tatggtttct tctgagctga ctcaggaccc tgcagtgtct
      121 gtggccttgg ggcagacagt caggattacc tgccaaggag acagcctcag aagctcttat
      181 gcaaactggt accaacagag gccaggccag gcccctgtgc tggtcgtcta tggtaacaac
      241 taccggccct cagggatccc agagcgattc tctggctcct actcccgaaa cacagcttcc
      301 ttgaccatca ctgggactca ggtggaagat gaggctgact attactgtga ctcctgggac
      361 agcagcggag cccaattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct
      421 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001633             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:9584:8157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001633
VERSION     KCWK01001633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:9584:8157"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..408
                     /note="immunoglobulin light chain variable region"
     V_region        84..408
     V_segment       84..371
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67371.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           85 a          143 c          122 g           96 t
ORIGIN      
        1 acatgggcat tgacggtgcc tcagccatgg cctggacttt tctcctcctc ggcctccttg
       61 cttactgcac aggctctgcg gcctccgatg atctgactca gccaccctcg gtgtcagtgt
      121 ccccaggaca gacggccagg atcacctgtg ggggagacaa cattggaagt aagagtgtgc
      181 actggtacca gcacaagcca ccgcaggccc ctatcctggt catctattat tataccgaac
      241 ggccctcggc gatccctgag cgattctctg gctccaaatc agggaacacc gccaccctga
      301 ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta ctgtcaggtg tgggacacta
      361 ctattgatca tggctttttc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001634             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:5607:15308
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001634
VERSION     KCWK01001634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:5607:15308"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    43..391
                     /note="immunoglobulin light chain variable region"
     V_region        43..391
     V_segment       43..352
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <319..>363
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67372.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       357..391
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        392..>429
                     /gene="IGLC"
BASE COUNT           83 a          143 c           99 g          104 t
ORIGIN      
        1 acatgggtcc tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag
       61 ccaacctccc tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt
      121 ggcatcaatg ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc
      181 cggttccttc tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc
      241 cgcttctctg gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc
      301 cagtctgaag atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta
      361 ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      421 ctcttcccg
//
LOCUS       KCWK01001635             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:11834:11508
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001635
VERSION     KCWK01001635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11834:11508"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..373
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67373.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       382..416
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           86 a          146 c          131 g           91 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacccttc tcctcctcgg
       61 cctcctcgct cactgcacag gctctgcgac ctcctatgag ctgactcagc caccctcggt
      121 gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca ttggaactaa
      181 atatgtgcac tggtaccagc agaagccagc gcaggcccct gtgttggtca tctatgctga
      241 taccagacgg ccctcaggga tccctgagcg attctctggc tccaactcag ggaacaccgc
      301 caccctgacc atcagcggtg tcgaggccgg gtatgaggct gactatttct gtcaggtgtg
      361 ggacgatagt agtgatcatc cggtattcgg cggagggacc cggctgaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001636             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:20880:5755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001636
VERSION     KCWK01001636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20880:5755"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67374.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          155 c          113 g          116 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttgctaatta caggatattc tggtaccgcc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcagggg ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001637             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:22725:19703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001637
VERSION     KCWK01001637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22725:19703"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67375.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           88 a          165 c          113 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaccaatg
      181 ttggtagtta cagcattttc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca actaagcacc ggggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccatttggc acagcagcgc ttcttgcatc ttcggtcctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001638             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:18407:15157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001638
VERSION     KCWK01001638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18407:15157"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67376.1"
                     /translation="DYYCCSRSTSSTYVF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           83 a          162 c          116 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt ataactctgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaagtc atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagt ctgaggacga
      361 ggctgattat tactgttgtt cacgttcaac cagtagcact tacgtcttcg gtcctgggac
      421 ccggctcacc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001639             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:14147:6898
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001639
VERSION     KCWK01001639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:14147:6898"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67377.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          156 c          127 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gttcccagga
      241 acagctccca aagtcctcat ctattatagt gatgaacgcg cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001640             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:11903:10720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001640
VERSION     KCWK01001640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11903:10720"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..394
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67378.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       408..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          153 c          123 g          111 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccccga
      121 ctcagactcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tattgggtat tatcatgctg tgtcttggta ccagcatcat ccaggcaaag
      241 cccccaaact catgatttat gaggtcaata aacggcccgc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag actgaggatg
      361 aggctgatta ttactgtagc tcatatgcag gcagcaacag tttattcttc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001641             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:13674:9464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001641
VERSION     KCWK01001641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13674:9464"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67379.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          157 c          118 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cgatatcttc
      241 tgagatacaa atcggactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacgcaggta ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001642             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:4124:14847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001642
VERSION     KCWK01001642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:4124:14847"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67380.1"
                     /translation="DYYCSAWDSSLTGALF"
     J_segment       409..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          157 c          122 g          107 t
ORIGIN      
        1 acatggggag cttcagctgt ggctagagaa gacaggactc aggacaatct ccagcatggc
       61 ctgcttccct ctcatcctca ccgtcctcac tcactgtgca ggatcctggg cccagtctgt
      121 gctgactcaa ccaccctcag cgtctggggc ccccgggcag agtgtcacca tctcctgttc
      181 tggaagcacc tccaacatcg gaagtaattt tgtatactgg taccagcagt tctcagggaa
      241 ggcccccaaa ctcctcatcc ataataatga tcagcgaccc tcaggggtcc ctgatcgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agtccgagga
      361 tgaggctgat tattactgct cagcatggga tagcagtctg accggtgcct tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01001643             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:22527:7229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001643
VERSION     KCWK01001643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22527:7229"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67381.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       414..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           93 a          162 c          125 g          107 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctcg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acacagccgc cctcagtgtc tggggcccca gggcagaggg tcaccatctc
      181 ctgcactggg agcagctcca acattggagg ttattatata tcctggtacc agcagctccc
      241 aggaacggcc cccaaactcc tcgtctatga caataataag cgaccctcag gggtttctga
      301 ccgattctct ggctccaagt ctggttcctc agccaccctg accatcactg ggctccagac
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agtctgagtg ctcgggtatt
      421 cggcggaggg acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01001644             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:13344:3996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001644
VERSION     KCWK01001644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13344:3996"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..440
                     /note="immunoglobulin light chain variable region"
     V_region        92..440
     V_segment       92..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67382.1"
                     /translation="DYYCAIGHMSGNYVF"
     J_segment       408..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           93 a          154 c          119 g          112 t
ORIGIN      
        1 acatgggggt gtggggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc caagcctatg ctgactcagc cggcctccct
      121 ctcagcatct cctggagcat cagccagtct cacatgcacc ttcagcggtg gcatcaatgt
      181 tgctggctac cacacacact ggtaccagca gaagccaggg agtcctcccc ggtatcttct
      241 gagatataaa tcagactcag ataagggcca gggctctgga gtccccagcc gcttctctgg
      301 atccaaagat gcttcagcga acacagggat tttacgcatc tctgggctcc agtctgagga
      361 tgaggctgac tattactgtg ccattgggca catgagcggt aattatgtct tcggttctgg
      421 gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01001645             332 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:15050:5108
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001645
VERSION     KCWK01001645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 332)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15050:5108"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..294
                     /note="immunoglobulin light chain variable region"
     V_region        6..294
     V_segment       6..257
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>266
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67383.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       259..294
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>332
                     /gene="IGLC"
BASE COUNT           70 a          102 c           84 g           76 t
ORIGIN      
        1 acatgggagg gacagtcact ctcacctgtg cttccagcac tggagcagtc accagtggtc
       61 actctccaca ctggttccag cagaaacctg gacaagcccc caagacactg atttataata
      121 caaactacag acactcctgg actcctgccc ggttctcagg ctccctcctt gggggtaaag
      181 ctgccctgac actgtcaggt gcgcagcctg aggatgaggc tgagtattat tgtttactgt
      241 actatagtgg tgctcagctg ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      301 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001646             349 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:19354:14286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001646
VERSION     KCWK01001646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 349)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19354:14286"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..309
                     /note="immunoglobulin light chain variable region"
     V_region        8..309
     V_segment       8..275
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <239..>283
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67384.1"
                     /translation="DYYCCSRSSSSTYVF"
     J_segment       276..309
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        310..>349
                     /gene="IGLC"
BASE COUNT           63 a          112 c           87 g           87 t
ORIGIN      
        1 acatggggtg tctgggtctc ctggacagtc ggtcaccatc tcctgcactg gaaccagcag
       61 tgacgttggt ggttataact ctgtctcctg gtaccaacaa cacccaggca aagcccccaa
      121 agtcatgatt tttggtgtca ataatcggcc ctctggggtc tctgaccgct tctctggctc
      181 caagtctggc aacacggcct ccctgaccat ctctgggctc cagtctgagg acgaggctga
      241 ttattactgt tgttcacgtt caagcagcag cacttacgtc ttcggtcctg ggacccggct
      301 caccgtcctg ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001647             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:4343:10107
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001647
VERSION     KCWK01001647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:4343:10107"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..449
                     /note="immunoglobulin light chain variable region"
     V_region        101..449
     V_segment       101..412
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67385.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           90 a          167 c          120 g          110 t
ORIGIN      
        1 acatggggct gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcgtccc cgggagcatc ggccagactc ccctgcaccc tgaccagtga
      181 cctcagcgtt gatactaaaa acatgtattg gtaccagcag aagccaggga gcgctcccag
      241 gtcattcctc tactactact ccgactcaga caagcagctg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt attactgtca ggtctatgac agtagtgcta atgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01001648             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:11521:13883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001648
VERSION     KCWK01001648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:11521:13883"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..255
                     /note="immunoglobulin light chain variable region"
     V_region        4..255
     V_segment       4..218
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <174..>227
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67386.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       219..255
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        256..>293
                     /gene="IGLC"
BASE COUNT           58 a           88 c           88 g           59 t
ORIGIN      
        1 acatggggaa tgtatatgct tactggttcc agcagaagcc aggccaggcc cctgtagtgg
       61 tcatctacaa agataccaac cggccctcag ggatccctga gcgattctct ggctccgact
      121 cagggaacac ggccaccctg accatcagca gggtcgaggc tggggatgag gccgactatt
      181 tttgtgctgc agcctatggc agtggcagca gctggcagtg ggtattcggc ggagggaccc
      241 ggctaatcgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001649             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:15809:11018
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001649
VERSION     KCWK01001649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15809:11018"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..395
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67387.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       397..432
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           94 a          151 c          115 g          110 t
ORIGIN      
        1 acatggggct gtagccaggg atcccttcca atatcagcac catggcctgg actctgctcc
       61 tcctccagtt cctcctcact tgctgcccag ggtccaattc tcaggctgta gtgactcagg
      121 agccctcaat gactgtgtcc ccaggaggga cagtcactct cacctgtgct tccagcactg
      181 gagcagtcac cagtggtcac tctccacact ggttccagca gaaacctgga caagccccca
      241 agacactgat ttataataca aactacagac actcctggac tcctgcccgg ttctcaggct
      301 ccctccttgg gggtaaagct gccctgacac tgtcaggtgc gcagcctgag gatgaggctg
      361 agtattattg tttactgtac tatagtggtg ctcagctgtt attcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001650             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18728:12350
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001650
VERSION     KCWK01001650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18728:12350"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67388.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          148 c          130 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg ccttcctatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt caaagtgtgc actggtacca gcacaagcca ccgcaggccc ctgttctggt
      241 catcttttat tataccgaac ggccctcagg aatccctgag cgaatctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacacaa gtcttgatca cggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001651             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:27225:16079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001651
VERSION     KCWK01001651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:27225:16079"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..343
                     /note="immunoglobulin light chain variable region"
     V_region        13..343
     V_segment       13..306
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <268..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67389.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       307..343
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>381
                     /gene="IGLC"
BASE COUNT           78 a          122 c           97 g           84 t
ORIGIN      
        1 acatgggggg cccagtctgt gctgactcag cctccctcag cgtctgaggc cgccaggaag
       61 agtgtcacca tctcctgttc tggaagcagc tccaacatcg gaagtaataa tgtgtcctgg
      121 taccagcacc tcccaggaac agctcccaaa ctcctcatct actataatga tcaacgaggc
      181 tcaggtgtct ctgaccgatt ctctggctcc aagtctggca cgtcagcctc cctggccatc
      241 agtgggctcc agaccgagga tgaggctgat tattactgcg cagcgtggga tgatagactg
      301 agcagttaca tcttcgctgc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc
      361 cccacggtca ctctgttccc g
//
LOCUS       KCWK01001652             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:15159:4472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001652
VERSION     KCWK01001652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15159:4472"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67390.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       402..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           92 a          158 c          111 g          113 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagt cagactcagc tgcaccttga gcagtggcat caatgttggt
      181 tcttacacca tattctggta ccagcagaag ccagggagtc ctccccggtt ccttctgtac
      241 tactactcag actcaaataa tcaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagccaatgc agggctttta ctgatctctg gactccagtc tgaagatgag
      361 gctgactatt actgtgccat gtggcacagc agcgcttatg ccttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001653             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:17204:12299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001653
VERSION     KCWK01001653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17204:12299"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..400
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67391.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           85 a          152 c          130 g          110 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg ttaccatctc ctgcactggg
      181 agcagctcca acatcggggc gggtttttat gtgtcctggt accagcagtt ccctggaaca
      241 gcccccaaac tcctcatctt tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggttc ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgctc atcatgggaa agcagcctga attgggtttt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001654             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:26378:8211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001654
VERSION     KCWK01001654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:26378:8211"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67392.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       394..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          143 c          137 g          100 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 gccaccctcg atttcagtgt ccccaggaca gacggccagg gtcacctgtg ggggagacaa
      181 catcggaggt gaagttgtga attggtacca gcagaagcca ccgcaggccc ctgtgttggt
      241 catctatgct gatagcgagc ggccctcagg gatccctgag cgattctctg gctccaaatc
      301 agggaacgcg gccaccctga ccatcagcgg ggtcgaggcc ggagatgagg ctgactatta
      361 ctgtcaggtg tgggacctta atagtcatca tctcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001655             321 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:27258:13752
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001655
VERSION     KCWK01001655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 321)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:27258:13752"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..283
                     /note="immunoglobulin light chain variable region"
     V_region        8..283
     V_segment       8..244
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <211..>255
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67393.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       246..283
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>321
                     /gene="IGLC"
BASE COUNT           63 a           95 c           89 g           74 t
ORIGIN      
        1 acatggggcg gtggcatcaa tgttgctgtc taccacgtac actggtacca gcagaagcca
       61 gggagtcccc cccggtatct tctgaggtac aaatcagact cagataaggg ccaggggtct
      121 ggggtcccca gccgcttctc tggatccagt aatgcttcag cgaacacagg gattttacgc
      181 atttctgggc tccagtctga ggatgaggct gactattact gtgccattgg gcacagcagc
      241 ggtctttaca tcttcggtgc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc
      301 cccacggtca ctctgttccc g
//
LOCUS       KCWK01001656             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11658:19967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001656
VERSION     KCWK01001656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11658:19967"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..278
                     /note="immunoglobulin light chain variable region"
     V_region        104..278
     V_segment       104..241
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <203..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67394.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       242..278
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>316
                     /gene="IGLC"
BASE COUNT           55 a          103 c           88 g           70 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg caggatcaac gagcctcagg
      121 tgtctctgac cgattctctg gctcccagtc tggcacgtca gcctccctgg ccatcagtgg
      181 gctccagacc gaggatgagg ctgattatta ctgcgcggca tgggatgata gcctgagcgg
      241 ttacatcttc ggtggtggga cccggctcac cgtcctaggt cagcccaagg cttcccccac
      301 ggtcactctg ttcccg
//
LOCUS       KCWK01001657             328 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:23312:12437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001657
VERSION     KCWK01001657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 328)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23312:12437"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..290
                     /note="immunoglobulin light chain variable region"
     V_region        8..290
     V_segment       8..252
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>262
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67395.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       254..290
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        291..>328
                     /gene="IGLC"
BASE COUNT           73 a           98 c           94 g           63 t
ORIGIN      
        1 acatggggga cagacggcca ggatcacctg tgggggagac aacattggaa gtcaaagtgt
       61 gcactggtac cagcacaagc caccgcaggc ccctgtactg gtcatctttt attataccga
      121 acggccctca ggaatccctg agcgattctc tggctccaaa tcagggaaca ccgccaccct
      181 gaccatcagc ggggtcgagg ccggggatga ggctgactat tactgtcagg tgtgggacac
      241 aactattgat cacggcttat tcggaggagg gacccggctg accgtcctag gtcagcccaa
      301 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001658             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:22658:17544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001658
VERSION     KCWK01001658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:22658:17544"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..423
                     /note="immunoglobulin light chain variable region"
     V_region        78..423
     V_segment       78..384
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67396.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       386..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           84 a          158 c          113 g          106 t
ORIGIN      
        1 acatgggagc cgtgtccacc atggccctga ctcctctcct cctcctgctc ctctctcact
       61 gcacaggttc cctctcccag cctgtgctga ctcagccacc ctccctgtct gcatccccgg
      121 gagcatcggc cagactcccc tgcaccctga gcagtgacct cagtgttggt agtaaaaaca
      181 tgtactggta ccagcagaag ccagggagcg ctcccaggtt attcctgtac tactactccg
      241 actcagacaa gcagctggga cctggggtcc ccaatcgagt ctctggctcc aaggagacct
      301 caagtaacac agcgtttttg ctcatctctg ggctccagcc tgaggacgag gccgattatt
      361 tctgccaggt gtttgacagt agtgttgtgt tcttcggagg agggacccga ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001659             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:17029:10366
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001659
VERSION     KCWK01001659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:17029:10366"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67397.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          162 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcaac ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001660             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:10957:18824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001660
VERSION     KCWK01001660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10957:18824"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67398.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          163 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agtagtgacc
      181 tcagtgttgg tagtaaaaac atctactggt accagctgaa gccagggagc gctcccaggt
      241 cattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga tgccgattat tactgtcagg tctatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001661             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:19486:4203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001661
VERSION     KCWK01001661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:19486:4203"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67399.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           96 a          157 c          118 g          109 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggaac atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctggct accacataca ctggtaccag cagaagccag ggagtcctcc ccgatatctt
      241 ctgagataca aatcggactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc gaacacaggg attttacgca tctctgggct ccagtctgag
      361 gatgaggctg actattactg tgccattgga cacagcagcg gtgattacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01001662             285 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:7818:2782
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001662
VERSION     KCWK01001662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 285)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7818:2782"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..247
                     /note="immunoglobulin light chain variable region"
     V_region        12..247
     V_segment       12..207
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <169..>219
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67400.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       211..247
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        248..>285
                     /gene="IGLC"
BASE COUNT           58 a           82 c           82 g           63 t
ORIGIN      
        1 acatgggaag ttgtcaactg gtaccagcag aagccaccgc aggcccctgt ggtggtcatc
       61 tatgctgatt atgaacggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      121 aacacggcca ccctgaccat cagcggagtc gaggccgggg atgaggctga ctattactgt
      181 caggtttggg acatttatat tgatcatccg gtgttattcg gaggagggac ccggctgacc
      241 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001663             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:11891:11864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001663
VERSION     KCWK01001663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:11891:11864"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..444
                     /note="immunoglobulin light chain variable region"
     V_region        96..444
     V_segment       96..407
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67401.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       410..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          165 c          114 g          111 t
ORIGIN      
        1 acatggggcc cactgcaggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcccagcc tgtgctgacc cagccaacct
      121 ccctctcagc atctccggga gcatcagcca gactcagctg caccttgagc agtggcatca
      181 gtgttggtac ttacagcata ttctggtacc agcagaagcc agggagtcct ccccggtacc
      241 ttctgtacta ccactcagac tcaagtaaac accagggctc tggagtcccc agccgcttct
      301 ctggatccaa agatgcttca gccaatgcag gtctgttact gatctctggg ctccagtctg
      361 aagatgaggc tgactattac tgtgccatat ggcacagcag cgcttcttgc atcttcggtg
      421 gtgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01001664             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:23957:7659
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001664
VERSION     KCWK01001664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23957:7659"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..386
                     /note="immunoglobulin light chain variable region"
     V_region        101..386
     V_segment       101..353
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <315..>362
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67402.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       354..386
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        387..>428
                     /gene="IGLC"
BASE COUNT           82 a          135 c          111 g          100 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg caggaagagt gtctccatct
      121 cctgttctgg aagcagctcc aacatcggaa gtcatagtgt ctcctggtac cagcagctcc
      181 caggaacagc tcccaaactc ctcatctatt atagtgatca acgagcctca ggtgtctctg
      241 accgattctc tggctctcag tctggcacgt cagcctccct ggccatcagt gggctccagg
      301 ccgaggatga ggctgattat tactgcgcag catgggatga tagtctgagc ggttacatct
      361 tcggtgctgg gacccggctc gccgtcgtag gtcagcccaa ggcttccccc acggtcactc
      421 tgttcccg
//
LOCUS       KCWK01001665             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22889:16848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001665
VERSION     KCWK01001665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22889:16848"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67403.1"
                     /translation="DYHCQVYDSSDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          161 c          121 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agtagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctata ctactactcc gactcagaca accagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtatgacag tagtgatgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001666             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:19882:13002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001666
VERSION     KCWK01001666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19882:13002"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..262
                     /note="immunoglobulin light chain variable region"
     V_region        1..262
     V_segment       1..226
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>234
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67404.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       230..262
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        263..>300
                     /gene="IGLC"
BASE COUNT           67 a           84 c           89 g           60 t
ORIGIN      
        1 acatgggggg gagacaacat tggaattaaa actgtacact ggtaccagca gaagccaccg
       61 cagggccctg tattggtcat ctttgctgat agtaagcggc cctcagggat ccctgagcga
      121 ttctctggct ccaactcagg gaacaccgcc accctgacca tcagcagggt cgaggccggg
      181 gatgaggctg actattactg tcaggtgtgg gacagtagta gtaaatggat attcggcggg
      241 gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001667             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:14299:10901
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001667
VERSION     KCWK01001667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14299:10901"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67405.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          162 c          124 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccagtcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001668             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:21803:8916
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001668
VERSION     KCWK01001668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21803:8916"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67406.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          155 c          120 g          112 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgtctacca cgtacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gttctggggt ccccagccgc ttctctggat
      301 ccagtaatac ttcagcgaac acagggattt tacgcgtttc tgggatccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtct ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001669             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:16535:19699
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001669
VERSION     KCWK01001669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16535:19699"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..297
                     /note="immunoglobulin light chain variable region"
     V_region        8..297
     V_segment       8..260
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <225..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67407.1"
                     /translation="DYSCAIGHSSGPYIF"
     J_segment       261..297
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>335
                     /gene="IGLC"
BASE COUNT           75 a          106 c           80 g           74 t
ORIGIN      
        1 acatgggcac atgcaccttc agcggtggca tcaatgttgc tgactaccac atacactggt
       61 accagcagaa gccagggagt cccccccggt atcttctgag ttacaaatca gactcagata
      121 agggccaggg ctctggagtc cccagccgct tctctggatc caaaaatact tcaacgaaca
      181 caggcatttt acacatctct gggctccagt ctgaggatga ggctgactat tcctgtgcca
      241 ttggacacag cagcggtcct tacatcttcg gtgctgggac ccggctcacc gtcctaggtc
      301 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001670             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:7043:11963
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001670
VERSION     KCWK01001670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7043:11963"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67408.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          156 c          126 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtaac catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcggcatgg gatgatagcc tgagaggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001671             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:22897:10284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001671
VERSION     KCWK01001671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22897:10284"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67409.1"
                     /translation="HYYCQVWDINSDHVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          142 c          132 g          102 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg atgttgtgaa ttggtaccac cagaagccac cgcaggcccc tgtactggtc
      241 atctatgcta ataccgatcg gccctcaggg atccctgagc gattctctgg ctccatatca
      301 gggaacacgg ccaccctgac catcaacggg gtcgaggccg gggatgaggc tcactattac
      361 tgtcaggtgt gggacattaa tagtgatcat gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001672             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:19561:15300
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001672
VERSION     KCWK01001672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19561:15300"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..427
                     /note="immunoglobulin light chain variable region"
     V_region        101..427
     V_segment       101..394
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67410.1"
                     /translation="DYHCSAGFGSGYSWQWVF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>469
                     /gene="IGLC"
BASE COUNT           92 a          149 c          131 g           97 t
ORIGIN      
        1 acatggggct ggcttcagaa gcagcatctg ggacatgtca gccatggcct ggacgcctct
       61 cctcctcagc ctcctcgctc actgcacagg ctctgtggcc tcctatgagc tgactcagcc
      121 accctcagtg tcggtgtccc caggacagac agccagcatc acctgctctg gagataaatt
      181 ggggaatgtt tatgcttatt ggtaccagca gaagccaggc caggccccta tactggtcat
      241 ctacaaagat agcaaccggc cctcagggat ccctgaccga ttctctggct ccaactcagg
      301 gaacacggcc accctgacca tcagcagggt cgaggctggg gatgaggccg actatcactg
      361 ttctgcaggc tttggcagtg ggtacagctg gcagtgggtt ttcggcggag ggacccggct
      421 aaccgtcgta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001673             450 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:22606:9895
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001673
VERSION     KCWK01001673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22606:9895"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..412
                     /note="immunoglobulin light chain variable region"
     V_region        82..412
     V_segment       82..373
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67411.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       375..412
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>450
                     /gene="IGLC"
BASE COUNT           83 a          144 c          116 g          107 t
ORIGIN      
        1 acatggggag ggacagtctc cagcatggcc tggtctcctc tcctcctcac ccttctcatt
       61 cactgcacag ggtcctgggc ccagtctgtg ctgacgcagc cgccctcagt gtctggggcg
      121 cccgggcaga gggtcaccat ctcctgcact gggagcagct ccaacattgg aggttattat
      181 gtgcagtggt accagcagct tccaggaacg gcccccaaac tcctcatcta tgaaaatgat
      241 aaacgaccct caggggtttc tgatcgattc tctggctccc agtctgattc ctcagcctcc
      301 ctgaccatca ctggactcca gtctgaggat gaggctgatt attactgcca gtcctatgac
      361 agcagcttga gtgttgtgtt attcggagga gggacccggc tgaccgtcct aggtcagccc
      421 aagtctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001674             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:11745:5732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001674
VERSION     KCWK01001674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:11745:5732"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67412.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          151 c          123 g          114 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggttcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat gttgggtatt ataacgctgt gtcttggtac caacagcatc caggcaaagc
      241 ccccaaactc atgatttatg acgtcattaa gcggccctca ggggtttctg atcgcttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagaaataat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001675             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:2669:10584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001675
VERSION     KCWK01001675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:2669:10584"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67413.1"
                     /translation="DYYCSSYAGSNTLVF"
     J_segment       400..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          156 c          122 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtagttata accgtgtctc ctggtaccaa catcaccccg acaaagcccc
      241 caaagtcatg atttatgagg gcagtcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caatactttg gtattcggcg gagggacccg
      421 tctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001676             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18062:10753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001676
VERSION     KCWK01001676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18062:10753"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67414.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           86 a          162 c          124 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta tttctgccag gtgtttgaca gtagtgttgt gttcttcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001677             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:13911:13643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001677
VERSION     KCWK01001677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13911:13643"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..403
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67415.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           85 a          162 c          122 g          111 t
ORIGIN      
        1 atgggggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggta gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaac cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattattt ctgccaggtg tttgacagta gtgttgtgtt cttcggagga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001678             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:5159:12340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001678
VERSION     KCWK01001678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5159:12340"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67416.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       391..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          149 c          136 g           92 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctatgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaag tatgtgcact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgttgat accagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg tatgaggctg actatttctg
      361 tcaggtgtgg gacgatagca gtgatcatcc ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001679             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:5206:7502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001679
VERSION     KCWK01001679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:5206:7502"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67417.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          148 c          129 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgcgcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001680             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:19894:12602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001680
VERSION     KCWK01001680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19894:12602"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67418.1"
                     /translation="VYYCGAWDSSLSGYIF"
     J_segment       413..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           95 a          157 c          126 g          110 t
ORIGIN      
        1 acatggggga agctctgcct cagctgtgag cacagaaggc aggacttggg acaatcttca
       61 tcatgacctg gtcccctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctacggcccc agggcagaag gtcaccatct
      181 cctgctctgg aagtagctcc aacatcggga gaaattctgt atcctggtac cagcaggtcc
      241 caggaacggc ccccaaagtc ctcatctatg acaataataa gcgcccctcg ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct ggccatcact ggactccagg
      361 ctggagatga ggctgtttat tactgcggag catgggatag cagtctgagt ggttacatct
      421 tcggtgatgg gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCWK01001681             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:8068:16461
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001681
VERSION     KCWK01001681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:8068:16461"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67419.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          148 c          122 g          107 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgta
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctctt gttctggaag catctccagc
      181 attggaagta gtgatgtatg ttggtaccag caactcccag gaacggcccc caaactcctc
      241 atcaattata gtgatcagcg actctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcct gggatagcag tctgagcagt ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgcaccctcg gtcactctct tcccg
//
LOCUS       KCWK01001682             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:16262:15257
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001682
VERSION     KCWK01001682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16262:15257"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67420.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       412..448
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           96 a          157 c          125 g          108 t
ORIGIN      
        1 acatggggag cgcagcttca gctgtgggta cagaaggcag gactcaggac aatctccagc
       61 atggcctggt tccctctcgt cctcaccctc ctcactcact gtgcagggtc ctgggcccag
      121 tctgtgctga ctcagcctcc ctcagcgtct gaggccgcca ggaagagtgt caccatctcc
      181 tgttctggaa gcagctccaa catcggaagt aataatgtgt cctggtacca gcacctccca
      241 ggaacagctc ccaaactcct catctattat aatgatcaac gaggctcagg tgtctctgac
      301 cgattctctg gctccaagtc tggcacgtca gcctccctgg ccatcagtgg gctccagacc
      361 gaggatgagg ctgattatta ctgcgcagcg tgggatgata ggctgagcag ttacatcttc
      421 gctgctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      481 ttcccg
//
LOCUS       KCWK01001683             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:25462:18371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001683
VERSION     KCWK01001683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:25462:18371"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..425
                     /note="immunoglobulin light chain variable region"
     V_region        95..425
     V_segment       95..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67421.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       395..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          152 c          117 g          107 t
ORIGIN      
        1 acatgggggg aggcagcgct ctcaggactt ctccaccatg gtctgggctc tgctcctcct
       61 caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc agactccctc
      121 tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca gcagtgatat
      181 tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc ccaaactcat
      241 gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg gctccaagtc
      301 tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg ctgattatta
      361 ctgcagctca tatgcaggca gcaacacttt attcttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001684             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:7179:4979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001684
VERSION     KCWK01001684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7179:4979"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..446
                     /note="immunoglobulin light chain variable region"
     V_region        101..446
     V_segment       101..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67422.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          163 c          122 g          110 t
ORIGIN      
        1 acatgggggg gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagcagtgc
      181 cctcagtgtt ggtaataaaa acatgtactg gtaccaacag aagccaggga gcgctcccag
      241 gttattcctg tactactact ccgactcaga caagcagctg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaactaa cacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt attactgtca ggtgtttgac agtagtgctg tgttattcgg
      421 aggagggacc cgactgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01001685             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:12916:3118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001685
VERSION     KCWK01001685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12916:3118"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67423.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           89 a          147 c          128 g           97 t
ORIGIN      
        1 atgggggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtcaaag tgtacactgg taccagcaca agccaccgca ggcccctgtt ctgctcatct
      241 tttattatac cgaacggccc tcaggaatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cacaactatt gatcacggct tgttcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001686             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:5028:8808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001686
VERSION     KCWK01001686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5028:8808"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67424.1"
                     /translation="DYYCAVWDDRLTGYVF"
     J_segment       415..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          157 c          124 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagcaat agtgtatcct ggtaccagca actcccagaa
      241 acggctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagtatgg gatgatcgcc tgaccggtta cgtattcggt
      421 gttgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001687             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:10525:11003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001687
VERSION     KCWK01001687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10525:11003"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67425.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          148 c          129 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtaca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttgttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001688             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:2081:13620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001688
VERSION     KCWK01001688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:2081:13620"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67426.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          128 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc acccttacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001689             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:6125:7007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001689
VERSION     KCWK01001689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6125:7007"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67427.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          160 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac ttatactggt accagcagaa gccagggagc tctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacga tagtgctgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001690             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:15292:4258
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001690
VERSION     KCWK01001690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:15292:4258"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67428.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          152 c          120 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcagtc actctcttcc cg
//
LOCUS       KCWK01001691             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:6380:15211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001691
VERSION     KCWK01001691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:6380:15211"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67429.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          154 c          128 g          113 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac catctcctgc
      181 actgggagca gctccaacat tggaggttat tatgtgcagt ggtaccagca gcttccagga
      241 gcggccccca aactcctcat ctatgaaaat gataaacgac cctcaggggt ttctgatcga
      301 ttctctggct cccagtctga ttcctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagcagct tgagtgttgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001692             407 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:5112:10287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001692
VERSION     KCWK01001692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 407)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5112:10287"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    39..369
                     /note="immunoglobulin light chain variable region"
     V_region        39..369
     V_segment       39..332
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <294..>341
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67430.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       333..369
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        370..>407
                     /gene="IGLC"
BASE COUNT           80 a          133 c          102 g           92 t
ORIGIN      
        1 acatgggcct cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagcctc
       61 cctcagcgtc tgaggccgcc aggaagagtg tcaccatctc ctgttctgga agcagctcca
      121 acatcggaag taataatgtg tcctggtacc agcacctccc aggaacagct cccaaactcc
      181 tcatctatta taatgatcaa cgaggctcag gtgtctctga ccgattctct ggctccaagt
      241 ctggcacgtc agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt
      301 actgcgcagc gtgggatgat agcctgagca gttacatctt cgctgctggg acccggctca
      361 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01001693             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:10160:7283
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001693
VERSION     KCWK01001693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:10160:7283"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67431.1"
                     /translation="EYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           85 a          161 c          119 g          103 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtgggcac
      181 tacagctata ccatcgcatg gcatcaacaa tatcaaggga aggcccctcg gttcttgatg
      241 tggcttaaaa gtgatggcag ccacaccaag ggggacggga tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctctcc atctccaacc tccagtctga ggatgaggct
      361 gagtattact gtcagacctg ggacattggc atttgggtat tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001694             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:18188:14632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001694
VERSION     KCWK01001694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18188:14632"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67432.1"
                     /translation="DYYCQVWDSSSEWVF"
     J_segment       390..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          147 c          136 g           92 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc agtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc aacagaaggc agcgcaggcc cctgtgctgg
      241 tcatctttgc tgataccaaa cggccctcag ggatccctga ccgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgagt gggttttcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001695             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:8154:10510
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001695
VERSION     KCWK01001695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8154:10510"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67433.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          162 c          111 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt actgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcgtattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001696             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:22763:11850
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001696
VERSION     KCWK01001696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22763:11850"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67434.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           95 a          162 c          122 g          106 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg acgcagccac
      121 cctccctgtc tgcatccccg ggagcaccgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatgttgg cagtcaaaac atgaactggt accaacagaa gccagggagc gctcccaggt
      241 tatttctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gatcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tatatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001697             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:23179:15526
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001697
VERSION     KCWK01001697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23179:15526"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..398
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67435.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       399..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           93 a          150 c          133 g           97 t
ORIGIN      
        1 acatggggga tcctggcttc agaagcagca tctgggacat gtcagccatg gcctggacgc
       61 ctctcctcct cagcctcctc gctcactgca caggctctgt ggcctcctat gagctgactc
      121 agccaccctc agtgtcggtg tccccaggac agacagccag catcacctgc tctggaaata
      181 aattggggaa tgtatatgct tactggttcc agcagaagcc aggccaggcc cctgtagtgg
      241 tcatctacaa agataccaac cggccctcag ggatccctga gcgattctct ggctccgact
      301 cagggaacac ggccaccctg accatcagca gggtcgaggc tggggatgag gccgactatt
      361 tttgtgctgc agcctatggc agtggcagca gctggcagtg ggtattcggc ggagggaccc
      421 ggctaatcgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001698             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:24106:2844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001698
VERSION     KCWK01001698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:24106:2844"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67436.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           92 a          145 c          134 g           93 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gaactgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc agcagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgacagtaaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001699             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:17055:21546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001699
VERSION     KCWK01001699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17055:21546"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67437.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          157 c          126 g          106 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agactccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagaaat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtccgcc tccctggcca tcagcgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001700             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16762:9748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001700
VERSION     KCWK01001700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16762:9748"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67438.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           96 a          158 c          121 g          109 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aagagtgtca ccatctcctg
      181 ttctggaagc acctccaaca tcggaagcaa taatgtatcc tggtaccagc agctcccagg
      241 aacagctccc aaactcctct tttattataa tgatcaacga gcctcaggtg tctctgaccg
      301 attctcttgc tccaagtctg gcacgtcagc ctccctggcc atcagtgggc tccagaccga
      361 ggatgaggct gattattact gcgcagcatg ggatgataac ctgagcggct acatcttcgg
      421 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01001701             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:5044:11405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001701
VERSION     KCWK01001701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5044:11405"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..385
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67439.1"
                     /translation="DYHCLAWDTSLNWIF"
     J_segment       394..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           90 a          152 c          116 g          104 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gcatctgggg cccccggaca gagggtcacc atctcctgca ttagcagcag ctccaacatc
      181 ggggcggctt attatgtatc ctggtaccaa cagttcccag gaacagcccc caaactcctc
      241 atctttgaaa ataataagcg accctctggg gtttctgacc gattctctgg ctccaagtct
      301 ggtccctcag cctccctgac catcactgga ctccaatctg aggatgaggc tgattatcac
      361 tgtttagcat gggataccag cctgaattgg atcttcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001702             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:16208:11615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001702
VERSION     KCWK01001702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16208:11615"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67440.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          150 c          116 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001703             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:18034:12626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001703
VERSION     KCWK01001703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18034:12626"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..406
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67441.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       408..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           97 a          157 c          112 g          117 t
ORIGIN      
        1 acatgggggc ccactgcagg gaaagaggct gtgtccacca tggcctggac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcgcagc ctgtgctgac tcagccaacc
      121 tccctctcag catctcctgg agcatcagcc agactcacct gcaccttgaa cagtggcatc
      181 agtgttgcta attacaggat attctggtac caccagaagc cagggagtcc tccccggtat
      241 cttctgaact accacacaga ctcagatatt catcagggct ctggagtccc cagccgcttc
      301 tctggatcca aagatgcttc ggccaatgca gggattttac tcatctctgg actccagtct
      361 gaggatgagg ctgactatta ctgtatgatt tggcacaaca atgcttattg ggttttcggc
      421 ggagggaccc ggctaaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001704             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:10851:18367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001704
VERSION     KCWK01001704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:10851:18367"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..249
                     /note="immunoglobulin light chain variable region"
     V_region        8..249
     V_segment       8..214
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67442.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       217..249
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        250..>289
                     /gene="IGLC"
BASE COUNT           56 a           87 c           85 g           61 t
ORIGIN      
        1 acatggggga actaaatatg tgcactggta ccagcagaag ccagcgcagg cccctgtgtt
       61 ggtcatctat gctgatacca gacggccctc agggatccct gagcgattct ctggctccaa
      121 ctcagggaac accgccaccc tgaccatcag cggggtcgag gccgggtatg aggctgacta
      181 tttctgtcag gtttgggacg atagtagtga tcatccggta ttcggcggag ggacccggct
      241 gaccgtcctt ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001705             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:23872:15118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001705
VERSION     KCWK01001705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23872:15118"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..441
                     /note="immunoglobulin light chain variable region"
     V_region        111..441
     V_segment       111..402
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67443.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           89 a          152 c          129 g          109 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctct ccttctcact ctgctggttc actgcacagg gtcctgggcc cagtctgtgc
      121 tgacgcagcc gccctcagca tctggggccc ccgggcagag ggtcaccatc tcctgcactg
      181 ggagcagctc caacatcggg gcgggttttt atgtatcctg gtaccagcag ttcccaggaa
      241 aagcccccaa gctcctcatc tttgaaaata acaagcgacc ctcaggggtt tctgaccgat
      301 tctctggctc caagtctggt tcctcagcct ccctgaccat cactggactc caatctgagg
      361 atgaggctga ttattattgt tcatcatggg aaagcagcct gaattgggta ttcggcggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001706             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:26180:7919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001706
VERSION     KCWK01001706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:26180:7919"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67444.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          155 c          121 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgactat tactgcagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001707             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:14719:11176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001707
VERSION     KCWK01001707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14719:11176"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67445.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          162 c          115 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctctgcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcagactca gatatggacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcctcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctactactgt gccattgggc acagcagcgg tgattacatc ttcgctgctg
      421 ggacccgcct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001708             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:22962:7336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001708
VERSION     KCWK01001708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22962:7336"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67446.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          141 c          136 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacgaccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001709             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:25115:9623
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001709
VERSION     KCWK01001709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25115:9623"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67447.1"
                     /translation="DYHCQVWDLNSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          142 c          136 g          100 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcga tttcagtgtc cccaggacag acggccaggg tcacctgtgg gggagacaac
      181 attgggagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atctatgctg atagcgagcg gccctcaggg atccctgaac gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactatcac
      361 tgtcaggtgt gggaccttaa tagtcatcat ttgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001710             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:24890:12542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001710
VERSION     KCWK01001710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:24890:12542"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67448.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       403..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          156 c          121 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca cgaggcagtg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtggccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tccggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttgttcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001711             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13469:14021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001711
VERSION     KCWK01001711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13469:14021"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..384
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67449.1"
                     /translation="DYYCQSAENSAKYYIF"
     J_segment       395..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          108 a          132 c          120 g          103 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatggtcagt ggttccagca gaagccaggt caggcccctg tgttggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ctctctagtt ccagttcagg
      301 aacaacactt accttgacca tcactggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagca gagaacagtg ctaagtatta tatattcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01001712             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:14893:4753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001712
VERSION     KCWK01001712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14893:4753"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..431
                     /note="immunoglobulin light chain variable region"
     V_region        107..431
     V_segment       107..394
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67450.1"
                     /translation="DYYCQVWDSSSDHVFF"
     J_segment       395..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           91 a          148 c          137 g           93 t
ORIGIN      
        1 acatggggca gcctgggcct caggaagcag ccttggcggt gcctcagcca tggcctggac
       61 ccttctcctc ctcggcctcc tcgctcactg cacaggctct gcggcctcct atgaaatgac
      121 tcagccgcgc tcagtgtctg tgtccccagg acagacggcc aggatcacct gtgggggaga
      181 caacattaga agtaaaaatg tgaattggta ccagcagaag ccaccgcagg cccccgcgct
      241 ggtcatctat tatgatagcg accggccctc agggatccct gagcgattct ctggctccaa
      301 ctcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      361 ttactgtcag gtgtgggaca gtagtagtga tcatgtgttt ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001713             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:11374:11542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001713
VERSION     KCWK01001713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11374:11542"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67451.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          155 c          125 g          106 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag actccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagaaatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agcgggctcc aggccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01001714             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:23240:4771
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001714
VERSION     KCWK01001714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:23240:4771"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67452.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          138 c          136 g          103 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgggcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001715             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:9306:5608
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001715
VERSION     KCWK01001715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:9306:5608"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..431
                     /note="immunoglobulin light chain variable region"
     V_region        110..431
     V_segment       110..395
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67453.1"
                     /translation="DYYCQVWDSTSKWTF"
     J_segment       400..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           93 a          147 c          134 g           95 t
ORIGIN      
        1 acatgggggc cctgtctggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggcc tcctcgctta ctgcacaggc tctgcgacct cctatgaact
      121 gactcagtca ccctcagtgt cagcggcctc aggacagtcg gccaggatca cctgtggggg
      181 agacaacatt ggaactaaaa ctgtgcactg gtaccagcag aagccaccgc agggccctgt
      241 attggtcatc tttgctgata gtaaacggcc gtcagggatc cctgagcgat tctctggctc
      301 caactcaggg aacaccgcca ccctgaccat cagcagggtc gaggccgggg atgaggctga
      361 ctattactgt caggtgtggg acagtactag taaatggaca ttcggcgggg ggacccggct
      421 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001716             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:16897:18943
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001716
VERSION     KCWK01001716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16897:18943"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..408
                     /note="immunoglobulin light chain variable region"
     V_region        90..408
     V_segment       90..376
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67454.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       377..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           88 a          139 c          121 g           98 t
ORIGIN      
        1 acatgggagc agagctctgg ggtgtctcca ccatggcctg gactcctctc tggctcaccc
       61 tcctcagtct ttgcacaggt tctatggttt cttctgagct gactcaggac cctgcagtgt
      121 ctgtggcctt ggggcagaca gtcaggatta cctgccaagg agacagcctc agaagttctt
      181 atgcaaactg gtaccaacag aggccaggcc aggcccctgt gctggtcgtc tatggtaaca
      241 actaccggcc ctcagggatc ccagaacgat tctctggctc ctcctcccga aacacagctt
      301 ccttgaccat cactggggct caggtggaag atgaggctga ctattactgt gactcctggg
      361 acagcagggg aacccaattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001717             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:16099:11152
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001717
VERSION     KCWK01001717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16099:11152"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67455.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          160 c          118 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcctcgg ccagactccc ctgcaccctg aacagtgacc
      181 tcaatattgg taataaaaac atgtactggt atcagcagaa gccagggagc gctcccaagt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcaaa cagcgttttt gttcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtt ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001718             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:10056:7354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001718
VERSION     KCWK01001718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10056:7354"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..419
                     /note="immunoglobulin light chain variable region"
     V_region        74..419
     V_segment       74..382
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67456.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       383..419
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           85 a          154 c          113 g          105 t
ORIGIN      
        1 acatggggtg tccaccatgg ccctgactcc tctcctcctc ctgctcctct ctcactgcac
       61 aggttccctc tcccagcctg tgctgactca gccaccctcc ctgtctgcat ccccgggagc
      121 atcggccaga ctcccctgca ccctgagcag tgacctcagt gttggtagta aaaacatgta
      181 ctggtaccag cagaggccag ggagcgctcc caggttattc ctgtattact actccgactc
      241 agacaagcag ctgggacctg gggtccccaa tcgagtctct ggctccaagg agacctcagg
      301 taacacagcg tttttgctca tctctggact ccagcctgag gacgaggccg attattactg
      361 tcaggtgtat gacagtagtg ctgtgttatt cggaggaggg acccgactga ccgtcctagg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001719             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:24483:5849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001719
VERSION     KCWK01001719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24483:5849"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67457.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          150 c          115 g          109 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtttcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001720             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:23590:9634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001720
VERSION     KCWK01001720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:23590:9634"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67458.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       408..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          153 c          116 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcaacggt ggcatcactg
      181 ttgctggcta ccatatatat tggtaccaac agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat atctggactc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tgattatatc ttcggtggtg
      421 ggacccgtct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001721             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:23678:18342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001721
VERSION     KCWK01001721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23678:18342"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67459.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          153 c          115 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccaaca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta ataatgtgtc ctggtaccag cacctcccag gaacagctcc caaactcctc
      241 atctattata atgatcaacg aggctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcgt gggatgatag cctgagcagt tacatcttcg ctgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001722             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:20413:20411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001722
VERSION     KCWK01001722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20413:20411"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..428
                     /note="immunoglobulin light chain variable region"
     V_region        100..428
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67460.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>468
                     /gene="IGLC"
BASE COUNT           93 a          150 c          116 g          109 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtccttg gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001723             394 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:19520:14320
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001723
VERSION     KCWK01001723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 394)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19520:14320"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..356
                     /note="immunoglobulin light chain variable region"
     V_region        9..356
     V_segment       9..317
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>328
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67461.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       319..356
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        357..>394
                     /gene="IGLC"
BASE COUNT           84 a          120 c           96 g           94 t
ORIGIN      
        1 acatggggag cctgtgctga ctcagccaac ctccctctca gcatctcctg gagcatcagc
       61 cagactcacc tgcaccttga acagtggcat cagtgttggt aattacagga tattctggta
      121 ccaccagaag ccagggagtc ctccccggta tcttctgaac taccacacag actcagatat
      181 tcaccagggc tctggagtcc ccagccgctt ctctgggtcc aaggatgctt cggccaatgc
      241 agggatttta ctcatctctg gactccagtc tgaggatgag gctgactatt actgtatgat
      301 ttggcacaac aatgcttatt gggtattcgg cggagggacc cggctaaccg tcctaggtca
      361 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001724             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:19724:10777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001724
VERSION     KCWK01001724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19724:10777"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..441
                     /note="immunoglobulin light chain variable region"
     V_region        94..441
     V_segment       94..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67462.1"
                     /translation="DYYCAIGHSSGNYIF"
     J_segment       408..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          156 c          119 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctat gctgactcag ccggcctcct
      121 tctcagcatc tcctggagct tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtttcttc
      241 tgagatacaa gtcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaagga tgcttcagcg aacacaggaa ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg taattatatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001725             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:20571:15746
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001725
VERSION     KCWK01001725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:20571:15746"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..434
                     /note="immunoglobulin light chain variable region"
     V_region        107..434
     V_segment       107..402
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67463.1"
                     /translation="DYYCSSYAGSKTLF"
     J_segment       403..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          157 c          124 g          104 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acaggcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtgctt ataactatgt ctcctggtac cagcagcacc caggcaaagc
      241 ccccaaactc atgatttatg atgtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctggcaacg cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaaaacg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001726             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:10477:9133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001726
VERSION     KCWK01001726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10477:9133"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67464.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       393..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           93 a          153 c          117 g          104 t
ORIGIN      
        1 acatgggggt acagaaggca ggactcagga caatctccag catggcctgg ttccctctcg
       61 tcctcaccct cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagcctc
      121 cctcagcgtc tgaggccgcc aggaagagtg tcaccatctc ctgttctgga agcagctcca
      181 acatcggaag taataatgtg tcctggtacc agcacctccc aggaacagct cccaaactcc
      241 tcatctatta taatgatcaa cgaggctcag gtgtctctga ccgattctct ggctccaagt
      301 ctggcacgtc agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt
      361 actgcgcagc gtgggatgat agcctgagca gttacatctt cgctgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01001727             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:8961:14465
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001727
VERSION     KCWK01001727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8961:14465"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67465.1"
                     /translation="EYFCSSYEGRNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          149 c          121 g          116 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggttcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt ataatgttgt gtcttggtac caacagcatc caggcaaagc
      241 ccccaaactc atgatttatg acgtcattaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggccaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgaatat ttctgcagct catatgaagg tagaaataat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001728             299 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:12018:18177
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001728
VERSION     KCWK01001728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 299)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12018:18177"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..261
                     /note="immunoglobulin light chain variable region"
     V_region        7..261
     V_segment       7..224
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <186..>233
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67466.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       229..261
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        262..>299
                     /gene="IGLC"
BASE COUNT           61 a           94 c           75 g           69 t
ORIGIN      
        1 acatgggctc caatattgga agtaattctg tatactggta ccagcagttc ccaggaacgg
       61 cccccaaact cctcatctat tatagtaatc agcgaccctc agtggtccct gaccgagtct
      121 ctggctctaa gtcgggcacc tcagcctccc tggccatcac tggtctccga tctgaggatg
      181 aggctgatta ttactgtgca gcatgggatg acagcctgag aagtccgcta ttcggcggag
      241 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001729             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:24951:20866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001729
VERSION     KCWK01001729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24951:20866"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..379
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67467.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       391..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          146 c          132 g           97 t
ORIGIN      
        1 acatgggggc tgggtctcag gaggcagcat tgacggtgcc tcagccatgg cctggaccct
       61 tctcctcctc ggcctcctcg ctcactgcac aggctctgcg acctcctttg agttgactca
      121 gccaccctcg gtgtcagcgg cctcaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaatt aaatttgtcc actggtacca gcagaagcca gcgcaggccc ctgtgaaggt
      241 catctatgct gatgacaaac ggccctcagg gatccctgag agattctctg gctccaattc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactattc
      361 ctgtcaggtg tgggacagtg agactgatta ttacatcttc ggtactggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001730             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15275:9287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001730
VERSION     KCWK01001730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15275:9287"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..398
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67468.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       400..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           87 a          151 c          120 g          113 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ttcaggctgc cccgactcag
      121 cctccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgatattg ggtattataa cgctgtgtct tggtaccaac agcatccagg caaagccccc
      241 aaactcataa tttttgacgt cattaagcgg ccctcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcgacacggc ctccctgacc atctctgggc tccgggctga ggatgaggct
      361 gattattact gcagctcata tgcaggcaga aataattttt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001731             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:16510:16746
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001731
VERSION     KCWK01001731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16510:16746"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    56..389
                     /note="immunoglobulin light chain variable region"
     V_region        56..389
     V_segment       56..352
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <320..>361
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67469.1"
                     /translation="DYYCQTWDIGIWIF"
     J_segment       353..389
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        390..>427
                     /gene="IGLC"
BASE COUNT           76 a          139 c          114 g           98 t
ORIGIN      
        1 atggggtcct tccttcaggc cataatgagt gtctctgttt tcagggtctc tctcccagcc
       61 tgtgctgact cagtcgccct ctgcctctgc ctccctggga gcctcggtca agctcacctg
      121 cactctgagc agtggccact acagctacac catcgcatgg catcagcagc aacaagggaa
      181 ggcccctcgg ttcttgatgt ggcttaagag tgatggcagc cacaccaagg gggacggggt
      241 ccctgatcgc ttctcaggct ccagctccgg ggctgagcgc tacctcacca tctccaacct
      301 ccagtctgag gatgaggctg attattactg tcagacctgg gacattggca tttggatatt
      361 cggcggaggg acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct
      421 cttcccg
//
LOCUS       KCWK01001732             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:21376:15000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001732
VERSION     KCWK01001732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:21376:15000"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..264
                     /note="immunoglobulin light chain variable region"
     V_region        5..264
     V_segment       5..224
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <186..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67470.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       228..264
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>302
                     /gene="IGLC"
BASE COUNT           64 a           84 c           89 g           65 t
ORIGIN      
        1 acatgggaga caacattgga agtgaagttg tcaactggta ccagcagagg ccaccgcagg
       61 cccctgtggt ggtcatctat gctgattatg aacggccctc agggatccct gagcgattct
      121 ctggctccaa atcagggaac acggccaccc tgaccatcag cggagtcgag gccggggatg
      181 aggctgacta ttattgtcag gtgtgggaca tttatattga ccatccggtg ttattcggag
      241 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      301 cg
//
LOCUS       KCWK01001733             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:7091:4187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001733
VERSION     KCWK01001733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7091:4187"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67471.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          137 c          135 g          104 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgtcccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001734             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:13182:12496
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001734
VERSION     KCWK01001734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13182:12496"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67472.1"
                     /translation="DYYCASYEGSNTFLF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          158 c          121 g          105 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca gtggaaccag
      181 cactaagatt gggtatcaca atgctgtgtc ctggtaccaa gagcatccag gcaaagcccc
      241 caaactcatg atttttgacg tcaataagcg gcccacaggg atctctgatc ggttctctgg
      301 ctccaagtct ggcgacacgg cctccctgac catctctggg ctccaggctg atgatgaggc
      361 tgattattac tgcgcctcat atgaaggcag caacactttc ctcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001735             401 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:8450:20192
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001735
VERSION     KCWK01001735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 401)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8450:20192"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    33..363
                     /note="immunoglobulin light chain variable region"
     V_region        33..363
     V_segment       33..326
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <288..>335
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67473.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       327..363
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        364..>401
                     /gene="IGLC"
BASE COUNT           78 a          127 c          107 g           89 t
ORIGIN      
        1 acatggggac tcactgtgca gggtcctggg cccagtctgt gctgactcag cctccctctg
       61 cgtctgaggc cgccaggaag agtgtcacca tctcctgttc tggaagcagc tccaacatcg
      121 gaaggaatag tgtatcctgg taccagcagc tcccaggaac agctcccaaa ctcctcatct
      181 attatagtga tcaacgagcc tcaggtgtct ctgaccgatt ctctggctcc aagtctggca
      241 tgtcagcctc cctggccatc agcgggctcc agaccgagga tgagggtgat tactactgcg
      301 cagcatggga tgatagcctg agcggttaca tcttcggtgc tgggacccgg ctcaccgtcc
      361 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01001736             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:22519:13456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001736
VERSION     KCWK01001736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22519:13456"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67474.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          155 c          126 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg acctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggcgcttata actatgtctc ctggtaccaa cagcatccag acacagcccc
      241 caaactgatg atttatgagg tcagtaagcg gctctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctgctcac atgcaggcag tgatattttc gtgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001737             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:18036:9368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001737
VERSION     KCWK01001737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18036:9368"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..398
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67475.1"
                     /translation="DYYCAAGYGSGSDWQWVF"
     J_segment       399..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           94 a          153 c          131 g           95 t
ORIGIN      
        1 acatggggga tcctggcttc agaagcagca tctgggacat gtcagccatg gcctggacgc
       61 ctctcctcct cagcctcctc gctcactgca caggctctgt ggcctcctat gacctgactc
      121 agccaccctc agtgtcggtg tccccaggac agacagccat catcacctgc tctggaaatg
      181 aattggggaa tgtatatgct tcctggtacc accagaagcc aggccaggcc cctgtattgg
      241 tcatctacaa agataccaac cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac ggccaccctg accatcagca gggtcgaggc tggggatgaa gccgactatt
      361 actgtgctgc aggctatggc agtgggagcg actggcagtg ggtattcggc ggggggaccc
      421 ggctaaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001738             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10886:12291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001738
VERSION     KCWK01001738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10886:12291"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..440
                     /note="immunoglobulin light chain variable region"
     V_region        92..440
     V_segment       92..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67476.1"
                     /translation="DYYCAMWHSSVYGLF"
     J_segment       403..440
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           95 a          155 c          113 g          115 t
ORIGIN      
        1 acatgggact gcagggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc ccagcctgtg ctgacccagc caacctccct
      121 ctcagcatct ccgggagcat cagccagact cagctgcacc ttgagcagtg gcatcaatgt
      181 tggtagttac agcatattct ggtaccagca gaagccaggg agtcctcccc gattccttct
      241 gtactactac tcagactcaa ataatcacca gggctctgga gtccccagcc gcttctctgg
      301 atccaaagat acttcagcca atgcagggct tttactgatc tctgggctcc agtctgaaga
      361 tgaggctgac tattactgtg ccatgtggca cagtagtgtt tatggcttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001739             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:20478:14397
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001739
VERSION     KCWK01001739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20478:14397"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..449
                     /note="immunoglobulin light chain variable region"
     V_region        116..449
     V_segment       116..412
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67477.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       413..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           84 a          169 c          129 g          105 t
ORIGIN      
        1 acatgggggc agtgtggctg cctcagcaga gccctgagga gtctgcacca tggcctggac
       61 cccaatcctc ctcctcctcc tcactctcct ccttcactgc acagggtctc tctcccagcc
      121 tgtgctgact cagtcgccct ctgcctctgc ctccctggga gcctcggtca agctcacctg
      181 cactctgagc agtggccact acagctacac catcgcatgg catcagcagc agcaagggaa
      241 ggcccctcgg ttcttgatgt ggcttaagag tgatggcagc cacaccaagg gggacggggt
      301 ccctgatcgc ttctcaggct ccagctccgg ggctgagcgc tacctcacca tctccaacct
      361 ccagtctgag gatgaggctg attattactg tcagacctgg gatattggca tttgggtatt
      421 cggcggaggg acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01001740             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:7032:14238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001740
VERSION     KCWK01001740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:7032:14238"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..347
                     /note="immunoglobulin light chain variable region"
     V_region        7..347
     V_segment       7..312
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <277..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67478.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       313..347
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        348..>387
                     /gene="IGLC"
BASE COUNT           79 a          125 c           91 g           92 t
ORIGIN      
        1 acatgggtgc tgacccagcc aacctccctc tcagcatctc cgggagcatc agccagactc
       61 agctgcacct ttagcagtgg catcaatgtt ggtagttaca gcatattctg gtaccagcag
      121 aagccaggga gtcctccccg gtaccttctc tactactact cagactcaag taaacaccag
      181 ggctctggag tccccagccg cttctctgga tccaaagatg cttcggccaa tgcaggcctt
      241 ttactgatct ctgggctcca gtctgaagat gaggctgact attactgtgc catatggcac
      301 agcagcgctt cttacttctt cggtagtggg acccggctca ccgtcctggg tcagcccaag
      361 gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01001741             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:10764:2428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001741
VERSION     KCWK01001741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10764:2428"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..427
                     /note="immunoglobulin light chain variable region"
     V_region        93..427
     V_segment       93..390
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67479.1"
                     /translation="DYYCMIWHNNAYWIF"
     J_segment       392..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>467
                     /gene="IGLC"
BASE COUNT           95 a          150 c          110 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttggtaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattagag cccccagccg cttctctggg tccaaggatg
      301 cttcggccaa tgcagggatt ttactcatct ctggactcca gtctgaggat gaggctgact
      361 attactgtat gatttggcac aacaatgctt attggatatt cggcggaggg acccggctaa
      421 ccgtcctggg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001742             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:23229:9512
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001742
VERSION     KCWK01001742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:23229:9512"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67480.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       392..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          140 c          135 g          103 t
ORIGIN      
        1 acatggggct gactttggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactttacag gctctgtggc ctcctatgag ttgcctcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtgtg ggagacaaca
      181 ttggaagtaa tagtgtgcat tggtaccagc agaagccacc gcgggcccct gtattggtca
      241 tctctgttga tagcgaacgg ccctcaggga tccctgagcg attctctggt tccagatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggataatatt tataaatacg cggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001743             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15953:5688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001743
VERSION     KCWK01001743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15953:5688"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67481.1"
                     /translation="DYYCQVYDSGANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          166 c          123 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggct ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagcgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tggtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001744             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:24301:17247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001744
VERSION     KCWK01001744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24301:17247"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67482.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          105 a          137 c          123 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctggg cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001745             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:22506:17927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001745
VERSION     KCWK01001745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22506:17927"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67483.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          151 c          116 g          107 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac ccctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001746             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15283:21203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001746
VERSION     KCWK01001746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15283:21203"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67484.1"
                     /translation="DYYCQSVDSSGNHPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          105 a          131 c          124 g          103 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tcttcacagg ctctgaggcc tcctatgggc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatgctcagt ggttccagca gaagccaggc caggcccctg tgttggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgaacga ttctctagtt ccagttcagg
      301 gacaacagtt accttgacca tcagtggggc ccaggtagaa gatgaggctg actattactg
      361 tcaatcagta gacagcagtg gtaatcatcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001747             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:10522:17992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001747
VERSION     KCWK01001747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10522:17992"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..251
                     /note="immunoglobulin light chain variable region"
     V_region        10..251
     V_segment       10..214
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67485.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       215..251
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           63 a           91 c           71 g           64 t
ORIGIN      
        1 acatgggcac tggtaccagc agaagccagg gagtcccccc cggtatcttc tgagttacaa
       61 atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg gatccaaaaa
      121 tgcttcaaca aacacaggca ttttacacat ctctgggctc cagtctgagg atgaggctga
      181 ctatttctgt gccattggac acagcagcgg tccttacatc ttcggtgctg ggacccggct
      241 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001748             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:12041:7981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001748
VERSION     KCWK01001748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12041:7981"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..392
                     /note="immunoglobulin light chain variable region"
     V_region        105..392
     V_segment       105..356
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <320..>364
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67486.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       357..392
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>430
                     /gene="IGLC"
BASE COUNT           91 a          133 c          114 g           92 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc catcctcact ttctgcacag gctctgcagc ctcctgtccc caggacagac
      121 ggccaggatc acctgctctg gagaagaatt gccaaaaaaa tatgcttatt ggttccagca
      181 gaagccaggc cagtcccctg tccagatcat ctatgaggac agtaaacggc cctctgggat
      241 ccctgagaga atctctggct ccagctcagg gacagtggcc accttgacta tcactggggc
      301 ccaggtggag gatgaagctg actactactg tttctcaaca gacaccagtg gtaatcgggt
      361 attcggcgga gggacccgtc taaccgtcct aggtcagccc aaggctgccc cctcggtcac
      421 tctcttcccg
//
LOCUS       KCWK01001749             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:21677:14299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001749
VERSION     KCWK01001749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21677:14299"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67487.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          151 c          121 g          111 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg tctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001750             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:23192:12099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001750
VERSION     KCWK01001750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23192:12099"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67488.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          137 c          121 g          102 t
ORIGIN      
        1 acatgggggc tgttgttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001751             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:15903:12487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001751
VERSION     KCWK01001751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15903:12487"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67489.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          154 c          121 g          112 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gttcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaacgag
      181 cagtgatatt ggctattata acgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 caaactcatc atttttgacg tcattaagcg gccctcaggg gtctctgatc gcttcgctgc
      301 ctccaagtct ggcgacacgg cctccctgac catctctggg ctccgggctg aggatgaggc
      361 tgattattac tgcagctcat atgccggcag aaataatttt ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001752             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:20484:6184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001752
VERSION     KCWK01001752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20484:6184"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67490.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           98 a          142 c          131 g           91 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga gctgactcag
      121 gcaccctcag tgtcagcggc ctcaggacag acggccagga tcacctgtgg cggagacaac
      181 attggaatta aaaatgtcca ctggtaccag cagaagccag cacaggcccc tgtggtagtc
      241 atctatgctg ataacaaacg gccctcaggg atccctgagc gactctctgg ctccaactca
      301 gggaatattg ccaccctgac catcagcagg gtcgaggccg gggatgaggc agactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg gtattcggcg gagggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001753             500 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:22929:13636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001753
VERSION     KCWK01001753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 500)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22929:13636"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    144..462
                     /note="immunoglobulin light chain variable region"
     V_region        144..462
     V_segment       144..430
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <393..>434
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67491.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       431..462
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        463..>500
                     /gene="IGLC"
BASE COUNT           96 a          155 c          138 g          111 t
ORIGIN      
        1 acatgggggc ccttcctatg ataagagagg actggaggtt ccccttagct gtgggctcag
       61 aagcagagct ctggggtgtc tccaccatgg cctggactcc tctctggctc accctcctca
      121 gtctttgcac aggttctctg gtttcttctg acctgactca ggaccctgcc gtgtctgtgg
      181 ccttgggaca gacagtcagg attacctgcc aaggagacag cctcagaagc tcttatgcaa
      241 gctggtacca gcagaggcca ggccaggccc ctgtgctggt cgtctatggt aacaactacc
      301 ggccctcagg gatcccagag cgattctctg gctcctactc acgaaacaca gcttccttga
      361 ccatctctgg ggctcaggtg gaagatgagg ctgactatta ctgtgactcc tgggacagca
      421 gcggaaccca attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      481 cctcggtcac tctcttcccg
//
LOCUS       KCWK01001754             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:19582:10143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001754
VERSION     KCWK01001754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19582:10143"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67492.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       396..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          142 c          140 g           97 t
ORIGIN      
        1 acatggggga gcctgacttt gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgctcacttt acaggctctg cggcctccta tgcggtgact
      121 cagccacgct cagtgtccgt gtccccagga caggcggcca ggatcacctg tgggggagac
      181 aacattggaa gtaaaagtgt ccagtggtac cagcagacgc caccgcaggc ccctgtactg
      241 gtcatttatg gtgataggga acggccctca gggatccctg aacgattctc tggctccaac
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggatag tagtagtaaa tatgtcttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001755             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:18411:4654
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001755
VERSION     KCWK01001755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18411:4654"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67493.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       401..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           87 a          157 c          125 g          105 t
ORIGIN      
        1 acatgggggg ggggtctcag gaggcagcgc tctcgggaca tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagcctcgct cagtgtctgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgaca tcggtggtta taactatgtc tcctggtacc aacagcatcc aggcacagcc
      241 cccaaagtca tgatttatga ggtcagtaag cggccctcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccaggc tgaggacgag
      361 gctgattatt actgcagctc atatacaggc atcaacagtt acatcttcgg tggtgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001756             411 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:19603:8551
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001756
VERSION     KCWK01001756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 411)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19603:8551"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    25..373
                     /note="immunoglobulin light chain variable region"
     V_region        25..373
     V_segment       25..333
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <301..>345
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67494.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       336..373
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        374..>411
                     /gene="IGLC"
BASE COUNT           84 a          137 c           99 g           91 t
ORIGIN      
        1 acatggggca caggttccct ctccaagcct atgctgactc agccggcctc cctctctgca
       61 tctcctggag catcagccag tctcacatgc accttcagcg gtggcatcaa tgttgctgcc
      121 taccacatac actggtacca gcagaagcca gggagtcctc cccggtatct tctgagatac
      181 aaatcagact cagatatgga ccagggctct ggagtcccca gccgcttctc tggatccaaa
      241 gatgcctcag cgaacacagg gattttacgc atctctgggc tccagtctga ggatgaggct
      301 gactactact gtgccattgg gcacagcagc ggtgattaca tcttcgctgc tgggacccgc
      361 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01001757             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:13321:13969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001757
VERSION     KCWK01001757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13321:13969"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67495.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          142 c          134 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaggccaccg caggcccctg tgctggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgcacga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001758             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:11793:18830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001758
VERSION     KCWK01001758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:11793:18830"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..440
                     /note="immunoglobulin light chain variable region"
     V_region        110..440
     V_segment       110..401
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67496.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       403..440
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           88 a          150 c          129 g          111 t
ORIGIN      
        1 acatgggggg cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctctc cttctcactc tgctggttca ctgcacaggg tcctgggccc agtctgtgtt
      121 gacgcagccg ccctcagcat ctggggcccc cgggcagagg gtcaccatct cctgcactgg
      181 gagcagctcc aacatcgggg cgggttttta tgtttcctgg taccagcagt tcccaggaac
      241 agcccccaaa ctcctcatct ttgaaaataa taagcgaccc tcaggggttt ctgaccgatt
      301 ctctggctcc aagtctggtt cctcagcctc cctgaccatc actggactcc aatctgagga
      361 tgaggctgat tattattgtt catcatggga aagcagcctg aattgggtat tcggcggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001759             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:20036:4141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001759
VERSION     KCWK01001759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:20036:4141"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67497.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          162 c          119 g          111 t
ORIGIN      
        1 acatgggggg gtctgtgtcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001760             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:19109:10165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001760
VERSION     KCWK01001760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19109:10165"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67498.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          141 c          135 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaggccac cgcaggcccc tgtgttggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001761             285 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:28021:16286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001761
VERSION     KCWK01001761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 285)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:28021:16286"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..247
                     /note="immunoglobulin light chain variable region"
     V_region        10..247
     V_segment       10..210
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <175..>219
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67499.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       213..247
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        248..>285
                     /gene="IGLC"
BASE COUNT           56 a           92 c           75 g           62 t
ORIGIN      
        1 acatggggtt atgtgcagtg gtaccagcag cgcccgggca gtgccccgac cacagtgatt
       61 tacagagata accaaagagc ctctggggtc cctgatcggt tctctggctc catcgacagc
      121 tcctccaact ctgcctccct caccatctct gggctgaagt ctgaggacga ggctgactac
      181 tactgtcagt ctactgatgg caactacaat cggttattcg gaggagggac ccggctgacc
      241 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001762             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:6440:8799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001762
VERSION     KCWK01001762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6440:8799"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67500.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       394..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           94 a          149 c          115 g          109 t
ORIGIN      
        1 acatggggga gccagggatc ccttccaata tcagcaccat ggcctggact ctgctcctcc
       61 tccagttcct cctcacttgc tgcccagggt ccaattctca ggctgtagtg actcaggagc
      121 cctcaatgac tgtgtcccca ggagggacag tcactctcac ctgtgcttcc agcactggag
      181 cagtcaccag tggtcactct ccacactggt tccagcagaa acctggacaa gcccccaaga
      241 cactgattta taatacaaac tacagacact cctggactcc tgcccggttc tcaggcttcc
      301 tccttggggg taaagctgcc ctgacactgt caggtgcgca gcctgaggat gaggctgagt
      361 attattgttt actgtactat agtggtgctc agctgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001763             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:14161:18080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001763
VERSION     KCWK01001763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14161:18080"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..274
                     /note="immunoglobulin light chain variable region"
     V_region        8..274
     V_segment       8..238
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>246
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67501.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       239..274
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        275..>312
                     /gene="IGLC"
BASE COUNT           74 a           87 c           90 g           61 t
ORIGIN      
        1 acatggggga tcacctgtgg cggagacaac attggaatta aaaatgtcca ctggtaccag
       61 cagaagccag cacaggcccc tgtggtagtc atctatgctg ataacaaacg gccctcaggg
      121 atccctgagc gactctctgg ctccaactca gggaatattg ccaccctgac catcagcagg
      181 gtcgaggccg gggatgaggc agactattac tgtcaggtgt gggacagtag tagtaaatgg
      241 gtattcggcg gagggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      301 actctcttcc cg
//
LOCUS       KCWK01001764             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:20291:17399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001764
VERSION     KCWK01001764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20291:17399"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67502.1"
                     /translation="DYHCQVYDGSAVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           86 a          160 c          125 g          112 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagtagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actacttctc cgactcagac aagcagttgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta tcactgtcag gtgtatgacg gtagtgctgt tttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001765             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20048:7110
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001765
VERSION     KCWK01001765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20048:7110"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..436
                     /note="immunoglobulin light chain variable region"
     V_region        90..436
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67503.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           91 a          160 c          111 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt tagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc tggggtccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gtagcgcttc ttacttcttc ggtactggga
      421 cccggctcac cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001766             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:20928:11826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001766
VERSION     KCWK01001766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20928:11826"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..282
                     /note="immunoglobulin light chain variable region"
     V_region        8..282
     V_segment       8..245
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67504.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       246..282
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>320
                     /gene="IGLC"
BASE COUNT           63 a          100 c           83 g           74 t
ORIGIN      
        1 acatgggcat ctcctgttct ggaggcagct ccaacatcgg cagtcatagt gtatcctggt
       61 accagcagct cccaggaaca gctcccaaac tcctcatcta ttatgatgat caacgagcct
      121 caggtgtctc tggccgattc tctggctcca ggtctggcac gtcagcctcc ctggccatca
      181 gtgggctcca gaccgaggat gaggctgatt attactgcgc agcatgggat gatagcctga
      241 gaggttacat cttcggtgat gggacccggc tcaccgtcct aggtcagccc aaggcttccc
      301 ccacggtcac tctgttcccg
//
LOCUS       KCWK01001767             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:17754:10745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001767
VERSION     KCWK01001767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17754:10745"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67505.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          153 c          121 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcccc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001768             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:23365:15540
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001768
VERSION     KCWK01001768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:23365:15540"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67506.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       412..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          163 c          125 g          106 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctcgtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac acagccgccc tcagtgtctg gggccccagg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatatatc ctggtaccag cagctcccag
      241 gaacggcccc caaactcctc gtctatgaca ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag ccaccctgac catcactggg ctccagactg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag tctgagcgct cgggtattcg
      421 gcggagggac ccggctaacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001769             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:5691:16616
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001769
VERSION     KCWK01001769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5691:16616"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..446
                     /note="immunoglobulin light chain variable region"
     V_region        98..446
     V_segment       98..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67507.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       412..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           93 a          164 c          120 g          107 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcactgacct
      181 cagtgttggt ggtaaaaaca tgtactggta ccagcagaag ccaggaagcg ctcccaggtt
      241 attgctgtat taccactccg actcagacaa ccagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcatttttg atcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtatgacagt agtgccaaca cgttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01001770             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:12438:15555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001770
VERSION     KCWK01001770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12438:15555"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67508.1"
                     /translation="DYYCQVFDDSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          159 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactacc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacga tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001771             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:16213:4572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001771
VERSION     KCWK01001771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16213:4572"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..216
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67509.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       221..251
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           59 a           87 c           74 g           69 t
ORIGIN      
        1 acatgggggg tattattatg ctgtgtcttg gtaccagcat catccaggca aagcccccaa
       61 gctcatgatt tatgaggtca ataaacggcc cgcaggggtc tctgatcgct tctctggctc
      121 caagtctggc aacacggcct ccctgaccat ctctgggctc cagactgagg atgaggctga
      181 ttattactgc agctcatatg caggcagcaa cactttattc ttcggaggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001772             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:13375:15208
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001772
VERSION     KCWK01001772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13375:15208"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..446
                     /note="immunoglobulin light chain variable region"
     V_region        98..446
     V_segment       98..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67510.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           90 a          163 c          120 g          111 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt ggtaaaaaca tgtactggta ccagcagaag ccagggcgcg ctcccaggtt
      241 tttcctgtac tacaactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcacgt atatgacagt agtactaatg tgttattcgg
      421 aggagggacc cgtctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01001773             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:10359:18030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001773
VERSION     KCWK01001773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:10359:18030"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..403
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67511.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           86 a          162 c          121 g          111 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggta gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattattt ctgccaggtg tttgacagta gtgttgtgtt cttcggagga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001774             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:14924:20124
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001774
VERSION     KCWK01001774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:14924:20124"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..436
                     /note="immunoglobulin light chain variable region"
     V_region        90..436
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67512.1"
                     /translation="DFFCAIGHSSGPYIF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           90 a          162 c          116 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcaactcc tggagcatca gccagtctca cgtgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catccactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 gtaacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcaacgaac acaggcattt tacacatctc tgggctccag tctgaggatg
      361 aggctgactt tttctgtgcc attgggcaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctcggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001775             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:23289:9670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001775
VERSION     KCWK01001775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23289:9670"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67513.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       399..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           94 a          151 c          117 g          110 t
ORIGIN      
        1 acatgggggt ctggagccag ggatcccttc caatatcagc accatggcct ggactctgct
       61 cctcctccag ttcctcctca cttgctgccc agggtccaat tctcaggctg tagtgactca
      121 ggagccctca atgactgtgt ccccaggagg gacagtcact ctcacctgtg cttccagcac
      181 tggagcagtc accagtggtc actctccaca ctggttccag cagaaacctg gacaagcccc
      241 caagacactg atttataata caaactacag acactcctgg actcctgccc ggttctcagg
      301 ctccctcctt gggggtaaag ctgccctgac actgtcaggt gcgcagcctg aggatgaggc
      361 tgagtattat tgtttactgt actatagtgg tgctcagctg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001776             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:6604:8616
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001776
VERSION     KCWK01001776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:6604:8616"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67514.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagtatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca aacagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001777             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:20763:10080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001777
VERSION     KCWK01001777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20763:10080"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67515.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          157 c          123 g          109 t
ORIGIN      
        1 acatgggggc agcctcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtatcct ggtaccaaca actcccagaa
      241 acggctccca aactcctcat gtattataat catcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacttcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagtatgg gatgatagcc tgaccggtta catcttcggt
      421 ggtgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001778             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:13617:22820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001778
VERSION     KCWK01001778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13617:22820"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67516.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          149 c          122 g          107 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgta
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctctt gttctggaag catctccagc
      181 attggaagta gtgatgtatg ttggtaccag caactcccag gaacggcccc caaactcctc
      241 atcaattata gtgatcagcg actctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcct gggatagcag cctgagcagt ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcctg
//
LOCUS       KCWK01001779             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:6919:6101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001779
VERSION     KCWK01001779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6919:6101"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67517.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       396..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          151 c          138 g           93 t
ORIGIN      
        1 acatgggggg tctgggtctc aggaggcagc attgacggtg cctcagccat ggcctggacc
       61 cttctcctcc tcggcctcct cgctcactgc acaggctctg cgacctccta tgagctgact
      121 cagccaccct cggtgtcagc ggcctcagga cagacggcca ggatcacctg tgggggagac
      181 aacattggaa ctaagtatgt gcactggtac cagcagaagc caccgcaggc ccctgtgttg
      241 gtcatctatg ctgataccag acggccctca gggatccctg agcgattctc tggctccaac
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccgggtatga ggctgactat
      361 ttctgtcagg tgtgggacga tagcagtgat catccggtat tcggcggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001780             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:2397:11731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001780
VERSION     KCWK01001780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:2397:11731"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..289
                     /note="immunoglobulin light chain variable region"
     V_region        8..289
     V_segment       8..253
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67518.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       257..289
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           73 a           93 c           98 g           63 t
ORIGIN      
        1 acatgggcag gacagccggc caggatcacc tgtgggggag acaacattgg aactaaaact
       61 gtgcactggt accaacagaa gccaccgcag ggccctgtat tggtcatctt tgctgatagt
      121 agacggccct cagggatccc tgagcgattc tctggctcca attcagggaa caccgccacc
      181 ctgaccatca gcagggtcga ggccggggat gaggctgact attactgtca ggtgtgggac
      241 agtagtagta aatggatatt cggcgggggg acccggctaa ccgtcctagg tcagcccaag
      301 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001781             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:21207:10698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001781
VERSION     KCWK01001781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21207:10698"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67519.1"
                     /translation="DYHCQVWDLNSHHLLF"
     J_segment       391..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          141 c          137 g           99 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcgat ttcagtgtcc ccaggacaga cggccagggt cacctgtggg ggagacaaca
      181 ttgggagtga agttgtgaac tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tctatgctga tagcgagcgg ccctcaggga tccctgaacg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactatcact
      361 gtcaggtgtg ggaccttaat agtcatcatt tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001782             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:16766:5250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001782
VERSION     KCWK01001782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16766:5250"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67520.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          145 c          139 g           93 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccag cgcacgcccc tgtgctggtc
      241 atctatgcta atagcgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg ggggtgaggc tgactattac
      361 tgtcaggtgt gggacatgcg tagtgatcaa ccgctattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001783             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:10966:4567
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001783
VERSION     KCWK01001783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:10966:4567"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..393
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67521.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           93 a          155 c          115 g          106 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtcaccatc tcctgttctg gaagcacctc
      181 caacatcgga agcaataatg tatcctggta ccagcagctc ccaggaacag ctcccaaact
      241 cctcttttat tataatgatc aacgagcctc aggtgtctct gaccgattct cttgctccaa
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca tcatgggatg ataccctgag cggctacatc ttcggtgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001784             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:15955:13456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001784
VERSION     KCWK01001784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:15955:13456"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67522.1"
                     /translation="DYYCQVFDDSAVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          160 c          121 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gaaataaaaa catatactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtcat acaacgtttt tgctcatttc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtttgacg atagtgctgt attattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001785             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:17587:16576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001785
VERSION     KCWK01001785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17587:16576"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..422
                     /note="immunoglobulin light chain variable region"
     V_region        98..422
     V_segment       98..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67523.1"
                     /translation="DYHCQVWDLNSHHLLF"
     J_segment       387..422
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           87 a          141 c          133 g           99 t
ORIGIN      
        1 acatggggcc tcaggaggca gcattgacgg tgcctcagcc atggcctgga cttttctcct
       61 cctcggcctc cttgcttact gcacaggctc tgcggcctcc tatgatctga ctcagccacc
      121 ctcgatttca gtgtccccag gacagacggc cagggtcacc tgtgggggag acaacattgg
      181 gagtgaagtt gtgaactggt accagcagaa gccaccgcag gcccctgtgt tggtcatcta
      241 tgctgatagc gagcggccct cagggatccc tgaacgattc tctggctcca aatcagggaa
      301 cacggccacc ctgaccatca gcggggtcga ggccggggat gaggctgact atcactgtca
      361 ggtgtgggac cttaatagtc atcatttgtt attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001786             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:13255:4374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001786
VERSION     KCWK01001786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:13255:4374"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67524.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          161 c          110 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaaat aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001787             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:23819:21255
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001787
VERSION     KCWK01001787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23819:21255"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67525.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       398..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          154 c          121 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctaca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagaccc
      241 caaattcatg atttatgagg tcagtcaacg gccctcaggt gtctctgatc gtatctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tggttattac tgcagctcat ttgcaggtac caacactggc ttaatcggtg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001788             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:16787:5002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001788
VERSION     KCWK01001788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16787:5002"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67526.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          154 c          119 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001789             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:13076:17013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001789
VERSION     KCWK01001789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13076:17013"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..396
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67527.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       397..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           91 a          154 c          120 g          106 t
ORIGIN      
        1 acatgggggg gtctcaggag gcggcactct cgggacatct ccaccatggc ctgggatctg
       61 ctcctcttca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 cctccctcaa tgtctgggtc tcctggacag tcggtcacca tctcctacac tggaaccagc
      181 agtgacattg gtggttataa ccatgtctcc tggtaccaac agcacccagg caaagacccc
      241 aaattcatga tttatgaggt cagtcaacgg ccctcagggg tctctgatcg tatctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 ggttattact gcagctcatt tgcaggtacc aacactggct taatcggtgg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001790             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:5923:10519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001790
VERSION     KCWK01001790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5923:10519"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..439
                     /note="immunoglobulin light chain variable region"
     V_region        93..439
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67528.1"
                     /translation="DYFCAIGHSSGLYIF"
     J_segment       404..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>479
                     /gene="IGLC"
BASE COUNT           86 a          158 c          121 g          114 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacgtacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa gtcagactca gataagggcc agggctctgg ggtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattgggc acagcagcgg tctttacatc ttcggtgctg
      421 ggacccggct caccgtcctt ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001791             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17719:17286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001791
VERSION     KCWK01001791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17719:17286"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..403
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67529.1"
                     /translation="DYYCSSYGGRNTLFF"
     J_segment       408..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          154 c          122 g          110 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccccga
      121 ctcagactcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tattgggtat tatcatgctg tgtcttggta ccagcatcat ccaggcaaag
      241 cccccaaact catgatttat gaggtcaata aacggcccgc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag actgaggatg
      361 aggctgatta ttactgcagc tcatatggag gcagaaacac tttattcttc gcaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001792             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:7639:13523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001792
VERSION     KCWK01001792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7639:13523"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..394
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67530.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           85 a          157 c          119 g          115 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcaa gctgccccga
      121 ctcagcctcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tattgggtct tatgatgctg tgtcttggta ccaacagcct ccaggcaaag
      241 ccccccaact cataattttt gaggtcaata agcggccctc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag gctgaggatg
      361 aggctgatta ttactgctgc tcatatgtag gcagcaacac ttacatcttc gatgttggga
      421 cccggctcac cgtcctaggt cagtccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001793             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:4136:14254
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001793
VERSION     KCWK01001793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:4136:14254"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67531.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          148 c          129 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tgggagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggcgt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001794             380 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:24170:19349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001794
VERSION     KCWK01001794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 380)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24170:19349"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..342
                     /note="immunoglobulin light chain variable region"
     V_region        12..342
     V_segment       12..305
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <267..>314
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67532.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       306..342
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        343..>380
                     /gene="IGLC"
BASE COUNT           77 a          121 c           97 g           85 t
ORIGIN      
        1 acatgggggc ccagtctgtg ctgactcagc ctccctcagc gtctgaggcc gccaggaaga
       61 gtgtcaccat ctcctgttct ggaagcagct ccaacatcgg aagtaataat gtgtcctggt
      121 accagcacct cccaggaaca gctcccaaac tcctcatcta ttataatgat caacgaggct
      181 caggtgtctc tgaccgattc tctggctcca agtctggcac gtcagcctcc ctggccatca
      241 gtgggctcca gaccgaggat gaggctgatt attactgcgc agcgtgggat gataggctga
      301 gcagttacat cttcgctgct gggacccggc tcaccgtcct aggtcagccc aaggcttccc
      361 ccacggtcac tctgttcccg
//
LOCUS       KCWK01001795             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:18192:10879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001795
VERSION     KCWK01001795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18192:10879"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67533.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001796             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:22160:11233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001796
VERSION     KCWK01001796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22160:11233"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67534.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          156 c          122 g          107 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaataa tgtgtcctgg taccagcacc tcccaggaac
      241 agctcccaaa ctcctcatct actataatga tcaacgaggc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcgtggga tgatagactg agcagttaca tcttcgctgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01001797             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:3243:15414
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001797
VERSION     KCWK01001797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:3243:15414"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67535.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       397..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           87 a          150 c          125 g          107 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gataatctcc agcatggcct ggttccctct
       61 cgtactcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 accctcagcg tctggggctc ccgggcagag tgtcaccatc tcttgttctg gaagcatctc
      181 cagcattgga agtagtgatg tatgttggta ccagcaactc ccaggaacgg cccccaaact
      241 cctcatcaat tatagtgatc agcgactctc aggggtccct gaccgattct ctggctctaa
      301 gtctggcacc tcagcctccc tggccatcac tggtctccga tctgaggatg aggctgatta
      361 ttactgtgca gcctgggata gcagcctgag cagtccggta ttcggcggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001798             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:19104:11128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001798
VERSION     KCWK01001798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19104:11128"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67536.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          143 c          141 g           92 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccagcg caggcccctg tgctggtcat
      241 ctatgctgat agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg ggtgaggctg actattactg
      361 tcaggtgtgg gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001799             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:21355:10546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001799
VERSION     KCWK01001799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21355:10546"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..412
                     /note="immunoglobulin light chain variable region"
     V_region        84..412
     V_segment       84..378
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <342..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67537.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       379..412
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>452
                     /gene="IGLC"
BASE COUNT           78 a          160 c          103 g          111 t
ORIGIN      
        1 acatgggctc tcaggacgtc tccaccatgg cctggactct gctcctcgtc accctcctca
       61 ctcaaggcac aggatcctgg gctcagtctg ccccgactca gcctccctct gtgtctgggt
      121 ctcctggaca gtcggtcacc atctcctgca ctggaaccac cagtgacgtt ggtggttcta
      181 actctgtctc ctggtaccaa caacacccag gcaaagcccc caaactcatg atttttggtg
      241 tcaataatcg gccctctggg gtctctgacc gcttctctgg ctccaagtct ggcaacacgg
      301 cctccctgac catctctggg ctccagtctg aggacgaggc tgattattac tgttgttcac
      361 attcaaccag tagcacttac gtcttcggtc ctgggacccg gctcaccgtc ctgggtcagc
      421 ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01001800             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:4283:10353
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001800
VERSION     KCWK01001800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4283:10353"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67538.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          156 c          119 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagtcagg gagtcctccc cggtatcttc
      241 taagatacaa atcagactca gatcagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacgggga ttttacacgt ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatt ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001801             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:18471:12871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001801
VERSION     KCWK01001801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18471:12871"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67539.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          137 c          140 g           98 t
ORIGIN      
        1 acatggggct gactttggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactttacag gctctgcggc ctcctatgag gtgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa aagtgtgcag tggtaccagc agacgccacc gcaggcccct gtactggtca
      241 tttatggtga tagggaacgg ccctcaggga tccctgagcg attctctggt tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggatagtagt agtaaatatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001802             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:19548:12721
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001802
VERSION     KCWK01001802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19548:12721"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67540.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       413..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          158 c          130 g          107 t
ORIGIN      
        1 acatgggggc gcagcttcag ctgtgggtac agaaggcagg actcaggaca atctccagca
       61 tggcctggtt ccctctcctc ctcaccctcc tcactcactg tgcagggtcc tgggcccagt
      121 ctgtgctgac tcagcctccc tcagcgtctg aggccgccag gaagagtgtc accatctcct
      181 gttctggaag cagctccaac atcggaagta atagtgtttc ctggtaccag cagctcccag
      241 aaacggctcc caaactcctc atcttttata atgatcggcg agcctcaggt gtctctgacc
      301 gattctctgg ctccaagtct ggcacgtcag cctccctggc catcagtggg ctccagaccg
      361 aggatgaggc tgattattac tgcgcagcat gggatgatag cctgagcggt ccggtattcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001803             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18185:9414
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001803
VERSION     KCWK01001803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18185:9414"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..411
                     /note="immunoglobulin light chain variable region"
     V_region        93..411
     V_segment       93..371
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67541.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       374..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           86 a          145 c          108 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacgtacac tggtatcttc tgaggtacaa atcagactca gataagggcc
      241 tgggctctgg agtccccagc cgcttctctg gatccaaaga tgcttcagcg aatacaggga
      301 ttttacacat ctctggtttc cagtctgagg atgaggctga ctattactgt gccattggcc
      361 acggcagcgg tgattacatc ttcggtactg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001804             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:11175:8614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001804
VERSION     KCWK01001804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11175:8614"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67542.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       398..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           84 a          156 c          117 g          116 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaagct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac cttctcctgc actggaaccg
      181 gcagtgattt tgggtcttat aatgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 cccaactcat aatttttgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgctgctca tatgtaggca gcaacactta catcttcgat gttgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01001805             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:5815:9976
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001805
VERSION     KCWK01001805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:5815:9976"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67543.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          147 c          131 g           96 t
ORIGIN      
        1 acatgggggg gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001806             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:14635:2462
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001806
VERSION     KCWK01001806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14635:2462"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67544.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           88 a          161 c          117 g          105 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggg
      181 cactacagct ataccatcgc atggcatcaa caatatcaag ggaaggcccc tcgattcttg
      241 atgtggctta aaagtgatgg cagccacacc aagggggacg ggatccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc tccatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatatt ggcatttggg tattcggcgg agggacccga
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001807             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:12119:18536
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001807
VERSION     KCWK01001807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12119:18536"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..422
                     /note="immunoglobulin light chain variable region"
     V_region        98..422
     V_segment       98..385
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67545.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       386..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          147 c          117 g          103 t
ORIGIN      
        1 acatgggggc tcagaagcag aactctgggt cctctccacc atggcctgga cccctcccct
       61 gctcatcctc ctcactctct gcacaggttc cgtggtttcc tctgagctga ctcaggagcc
      121 tgcattgtct gtggccttgg gacaaacagt caggatgacc tgccaaggag acagcctcaa
      181 aacctattat gcaagctggt accagcagaa gccaggccag gtccctgtgc tggtcatcta
      241 tggtaacaac taccggccct cagggatccc aggccgattc tctgtctcct ggtcaggaaa
      301 cacaggttcc ttgaccatca ctgcggctca ggtggaagat gaggctgact attactgtaa
      361 gtcctgggac agcagtggta cccattacat cttcggtgct gggacccggc tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01001808             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:8246:12602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001808
VERSION     KCWK01001808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8246:12602"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67546.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          161 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc accaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001809             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:23529:23833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001809
VERSION     KCWK01001809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23529:23833"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67547.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          120 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctgtggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001810             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:17801:10932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001810
VERSION     KCWK01001810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17801:10932"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67548.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           94 a          157 c          120 g          110 t
ORIGIN      
        1 acatggggag cctcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcctcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gttgactcag cctccctcag cgtctgaggc cgccgggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaatag tgtatcctgg taccaacaac tcccagaaac
      241 ggctcccaaa ctcctcatgt attataatca tcggcgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggcc cttcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagtatggga tgatagcctg accggttaca tcttcggtac
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01001811             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:21606:2952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001811
VERSION     KCWK01001811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21606:2952"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67549.1"
                     /translation="EYYCSSYTGINSYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          158 c          125 g          105 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaagtc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgagtat tactgcagct catatacagg catcaacagt tacatcttcg gtggtgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001812             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:5095:5924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001812
VERSION     KCWK01001812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:5095:5924"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    69..394
                     /note="immunoglobulin light chain variable region"
     V_region        69..394
     V_segment       69..359
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <326..>367
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67550.1"
                     /translation="DYYCQSADGNYRVF"
     J_segment       360..394
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>433
                     /gene="IGLC"
BASE COUNT           78 a          151 c          109 g           95 t
ORIGIN      
        1 acatgggatg gcctgggctc cactcctcct caccctcctc gctcactgca cagggtcttg
       61 ggctgaactt gtgttcactc agccccattc tgtgtcgggg tctccggggc agacggtcac
      121 catctcctgc acccgcagca ttggcaacat tgacagtgaa tatgtgcagt ggtaccagca
      181 gcgcccgggc agtgccccca ccacactgat ttacaaagat agtcaaagac cctctggggt
      241 ccctgaccgg ttctctggct ccatcgacag ctcctccaac tctgcctccc tcgccatctc
      301 tgggctacag tctgaggacg aggctgacta ctactgtcag tctgctgatg gcaactacag
      361 ggtcttcggc ggagggaccc ggctaaccgt cctaagtcag cccaaggctg ccccctcggt
      421 cactctcttc ccg
//
LOCUS       KCWK01001813             523 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:12075:16676
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001813
VERSION     KCWK01001813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 523)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 523)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..523
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12075:16676"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    161..482
                     /note="immunoglobulin light chain variable region"
     V_region        161..482
     V_segment       161..448
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <410..>457
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67551.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       451..482
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        483..>523
                     /gene="IGLC"
BASE COUNT          108 a          154 c          164 g           97 t
ORIGIN      
        1 acatgggggg agcgagaggc tgagagagtc ggagacacta tccgcttcca tccgtcgcgc
       61 agaccctgcc ggagccgctg ccgctatgga tgatcgagag gatctggtgt accaggcgaa
      121 gctggccgag caggctgagc gatacgacga ctctgcggcc tcctatgatc tgactcagcc
      181 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      241 tggaggtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tcctggtcat
      301 ctatgctaat aacgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      361 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      421 tcaggtgtgg ggtgttacta gtgatcatcc cttattcgga ggagggaccc ggctgaccgt
      481 ccaaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001814             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:12218:10773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001814
VERSION     KCWK01001814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12218:10773"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67552.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          150 c          126 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gactctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attgcaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcaccggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001815             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:18370:18323
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001815
VERSION     KCWK01001815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18370:18323"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..397
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67553.1"
                     /translation="DYYCSSYAGSNTHWLF"
     J_segment       407..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          159 c          120 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcaggacgtc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccag ctacacccag gcaaagcccc
      241 caaactcatg atttatgatg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaaatct gacaacacgg cctccctgac catctctggg ctccaggctg aggatgagac
      361 tgattattac tgcagctcat atgcaggcag caacactcat tggcttttcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001816             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:17815:4288
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001816
VERSION     KCWK01001816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17815:4288"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67554.1"
                     /translation="DYYCQVWDSDSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           96 a          143 c          133 g           92 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggtactgc gacctcctat gaactgactc
      121 agccaccctc agtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaac taaaaatgtg cactggtacc agcagaagcc agcgcagggc cctgtattgg
      241 tcatgtttgc tgataccaga cggccctcag ggatccctga ccgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt gatagtaaat ggatattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001817             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:12493:17066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001817
VERSION     KCWK01001817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12493:17066"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67555.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          130 g           95 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggca ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001818             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:7976:14368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001818
VERSION     KCWK01001818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7976:14368"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67556.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           97 a          158 c          123 g          105 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agactccctc agcgtctgag gccgccagaa agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagaaat agtgtaccct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagcgggct ccagaccgac
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001819             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:17054:7979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001819
VERSION     KCWK01001819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17054:7979"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..426
                     /note="immunoglobulin light chain variable region"
     V_region        103..426
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67557.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>465
                     /gene="IGLC"
BASE COUNT           91 a          147 c          129 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttatttg gaggagggac ccggctgacc
      421 gtcctaagtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001820             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:21439:3455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001820
VERSION     KCWK01001820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21439:3455"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..404
                     /note="immunoglobulin light chain variable region"
     V_region        80..404
     V_segment       80..355
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <329..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67558.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       367..404
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>442
                     /gene="IGLC"
BASE COUNT           88 a          140 c          120 g           94 t
ORIGIN      
        1 acatggggac ggtgcctcag ccatggcctg gacccttctc ctcctcggcc tcctcgctca
       61 ctgcacaggc tctgcgacct cttttgagct gactcagcca ccctcggtgt cagcggcctc
      121 aggacagacg gccaggatca cctgtggggg agacaacatt ggaattaaat ttgtccactg
      181 gtaccagcag aagccagcgc aggcccctgt gaaggtcatc tatgctgatg acaaacggcc
      241 ctcaggaatc cctgagagat tctctggctc caattcaggg aacaccgcca ccctgactat
      301 cagcggggtc gaggccgggg atgaggctga ctattcctgt caggtgtggg acagtgagac
      361 tgattattac atcttcggtt ctgggacccg actcaccgtc ctaggtcagc ccaaggcttc
      421 ccccacggtc actctgttcc cg
//
LOCUS       KCWK01001821             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:5951:3361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001821
VERSION     KCWK01001821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5951:3361"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..391
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67559.1"
                     /translation="DYYCAAWDDRLTGYVF"
     J_segment       398..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          154 c          119 g          104 t
ORIGIN      
        1 acatggggga cagaaggcag gactcaggac aatctccagc atggcctggt tccctctcct
       61 cctcaccctc ctcactcact gtgcagggtc ctgggcccag tctgtgctga ctcagcctcc
      121 ctcagcgtct gaggccgcca ggaagagtgt caccatctcc tgttctggaa gcagctccaa
      181 catcgggagc aatagtgtat cctggtacca gctgctccca gaaacggctc ccaaactcct
      241 catctattat aataatcggc gagcctcagg tgtctctgac cgattctctg gctccaagtc
      301 tggcacgtca gcctccctgg ccatcagtgg gctccagacc gaggatgagg ctgattatta
      361 ctgcgcagca tgggatgatc gcctgaccgg ttacgtattc ggtgttggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001822             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:20486:20245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001822
VERSION     KCWK01001822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20486:20245"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67560.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       396..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          156 c          121 g          102 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct cgtctcctct
       61 cctcctcacc cttttcattc actgcacagg gtcctgggcc cagtctgtgc tgacacagcc
      121 gccctcagtg tctggggccc cagggcagag ggtcaccatc tcctgcactg ggagcagctc
      181 caacattgga ggttattata tatcctggta ccagcagctc ccaggaacgg cccccaaact
      241 cctcgtctat gacaataata agcgaccctc aggggtttct gaccgattct ctggctccaa
      301 gtctggttcc tcagccaccc tgaccatcac tgggctccag actgaggatg aggctgatta
      361 ttactgccag tcctatgaca gcagtctgag tgctcgggta ttcggcggag ggacccggct
      421 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001823             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:21274:12312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001823
VERSION     KCWK01001823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21274:12312"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..390
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67561.1"
                     /translation="DYYCLEWHDSLSTGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          148 c          119 g          104 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactccac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 acatctgggg cccccgggca gagggtcacc atctcctgca ctgggaacag ccccaatatc
      181 ggggcgaatt attatgtatc gtggtaccag catttcccag gaacagcccc caaactcctc
      241 atctatgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggtacctcag cctccctgac catcactggg ctccagtctg aggatgaggc tgattattac
      361 tgcttagaat ggcatgatag cctgagtact ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001824             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:9565:13684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001824
VERSION     KCWK01001824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9565:13684"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..379
                     /note="immunoglobulin light chain variable region"
     V_region        88..379
     V_segment       88..342
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>351
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67562.1"
                     /translation="DYYCASWDSGGAHGLF"
     J_segment       343..379
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        380..>417
                     /gene="IGLC"
BASE COUNT           79 a          129 c          114 g           95 t
ORIGIN      
        1 tcagaagcag agctctgggg tgtctccacc atggcctgga ctcctctctg gctcaccctc
       61 ctcagtcttt gcacaggttc tgtggtttct tctgacctga ctcaggaccc tgcagtgtct
      121 gtggccttgg gacagacagt cataatcacc tgccaaggag acagcctcag aagttattat
      181 gcaagctggt tccaacagaa gccaggccgg gcccctgtgc tggtcgtcta tggtaacaac
      241 taccggccct caagaaacac agcttccttg accatcgctg gggctcaggt ggaagatgag
      301 gctgactatt actgtgcctc ctgggacagc ggcggtgccc atggcttatt cggaggaggg
      361 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001825             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:27019:10551
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001825
VERSION     KCWK01001825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:27019:10551"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67563.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           90 a          156 c          125 g          110 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcaag tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg aggggttaca tcttcgctgc
      421 tgggacccgg ctcgccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01001826             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:27446:8391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001826
VERSION     KCWK01001826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:27446:8391"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67564.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          162 c          123 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgctgg tactaaaaag atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gatcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001827             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:6379:5090
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001827
VERSION     KCWK01001827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6379:5090"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67565.1"
                     /translation="DYYCQVWDISSDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          142 c          133 g          100 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagc ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacct
      181 tggatatgaa gttgtcaact ggtaccaaca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcaacggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacattagta gtgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001828             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:19939:13631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001828
VERSION     KCWK01001828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:19939:13631"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67566.1"
                     /translation="DYYCQSYDSSLRGVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           85 a          156 c          131 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagttccaac attggaggtt tttatgtgca gtggtaccag caccttccag
      241 gaacggcccc caaactcctc atctatgaaa ataatgagcg accctcaggg gtttctgatc
      301 gattctctgg ttcccagtct ggcacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cttgcgtggt gtgttgttcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001829             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:21449:24343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001829
VERSION     KCWK01001829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21449:24343"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67567.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          123 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001830             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11053:11006
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001830
VERSION     KCWK01001830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11053:11006"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67568.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       407..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           90 a          161 c          125 g          104 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tcgtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacacagc cgccctcagt gtctggggcc ccagggcagg gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg aggttattat atatcctggt accagcagct cccaggaacg
      241 gcccccaaac tcctcgtcca tgacaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggttc ctcagccacc ctgaccatca ctgggctcca gactgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagtctga gtgctcgggt attcggcgga
      421 gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001831             274 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:11673:7717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001831
VERSION     KCWK01001831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 274)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 274)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:11673:7717"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..236
                     /note="immunoglobulin light chain variable region"
     V_region        3..236
     V_segment       3..199
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <161..>208
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67569.1"
                     /translation="DYYCQVWDSSSDHYIF"
     J_segment       203..236
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        237..>274
                     /gene="IGLC"
BASE COUNT           56 a           85 c           77 g           56 t
ORIGIN      
        1 acatgggcac tggtaccagc agaatccacc gcaggcccct gtgcaggtca tctttgcgga
       61 taacaaacgg ccctcaggga tccctgaacg attctctggc tccaactcag ggaacaccgc
      121 caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg
      181 ggacagtagt agtgatcatt atatcttcgg tggtgggacc cggctcaccg tcctaggtca
      241 gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001832             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:21743:4934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001832
VERSION     KCWK01001832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:21743:4934"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67570.1"
                     /translation="DYYCQSYDSSLTGVLF"
     J_segment       412..446
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           90 a          156 c          125 g          113 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca ccatctcctg
      181 cagtgggagc aactccaaca ttggatacta ttatgtgcag tggtaccagc agcttccagg
      241 aacggccccc aaactcctca tctatgaaaa taataagcga ccctctgggg tttctgatcg
      301 attctctggc tcccagtctg gtacctcagc ctccctgacc atcactggac tccagtctga
      361 ggatgaggct gattattact gccagtccta tgacagcagt ttgactggtg tcttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01001833             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:15101:8382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001833
VERSION     KCWK01001833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15101:8382"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67571.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          160 c          112 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcaactcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ttgcctacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 gttacgaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaaaatgc ttcaacaaac acaggcattt tacacatctc tgggctccag tctgaggatg
      361 aggctgacta tttctgtgcc attggacaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001834             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18155:12146
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001834
VERSION     KCWK01001834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18155:12146"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67572.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          159 c          119 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcatcatgg gatgataccc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001835             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:24882:9181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001835
VERSION     KCWK01001835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24882:9181"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..434
                     /note="immunoglobulin light chain variable region"
     V_region        86..434
     V_segment       86..395
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67573.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       397..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           94 a          152 c          112 g          114 t
ORIGIN      
        1 acatgggggg aaagaggctg tgtccaccat ggcctggact cctctcctcc tcctgctcct
       61 ctctcactgc acaggttccc tctcgcagcc tgtgctgact cagccaacct ccctctcagc
      121 atctcctgga gcatcagcca gactcacctg caccttgaac agtggcatca gtgttggtaa
      181 ttacaggata ttctggtacc accagaagcc agggagtcct ccccggtatc ttctgaacta
      241 ccacacagac tcagatattc accagggctc tggagtcccc agccgcttct ctgggtccaa
      301 ggatgcttcg gccaatgcag ggattttact catctctgga ctccagtctg aggatgaggc
      361 tgactattac tgtatgattt ggcacaacaa tgcttattgg gtattcggcg gagggacccg
      421 gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001836             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:22044:18406
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001836
VERSION     KCWK01001836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22044:18406"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..403
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67574.1"
                     /translation="DYYCASYEGSNTFLF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          159 c          122 g          106 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcagtggaac
      181 cagcactaag attgggtatc acaatgctgt gtcctggtac caagagcatc caggcaaagc
      241 ccccaaactc atgatttttg acgtcaataa gcggcccaca gggatctctg atcggttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccagg ctgatgatga
      361 ggctgattat tactgcgcct catatgaagg cagcaacact ttcctcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001837             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:5115:19679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001837
VERSION     KCWK01001837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5115:19679"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67575.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       409..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           90 a          161 c          119 g          110 t
ORIGIN      
        1 atgggggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 aatattggca ataaaaacat gtactggtac cagcagaagc cagggagcgc tcccaagtta
      241 ttcctgtact actactccga ctcagacatg cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtcataca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcaggtg tatgacagta gtgctgtatt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001838             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:24219:16890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001838
VERSION     KCWK01001838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24219:16890"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67576.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          151 c          120 g          112 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gttcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atcccctgca ctggaaccag
      181 cagtgatatt gggtattata acgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 caaactcatg atttatgacg tcattaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag aaataatttt ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001839             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:16419:17586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001839
VERSION     KCWK01001839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16419:17586"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67577.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          161 c          112 g          114 t
ORIGIN      
        1 acatggggga ctgcatggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcatcaat
      181 gttggtagtt acagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
      241 ctgtactact actcagactc aagtaaacac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatgcaggc cttttagtga tctctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccatatgg cacagcagcg cttcttactt cttcggtact
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01001840             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:14353:7951
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001840
VERSION     KCWK01001840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14353:7951"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..424
                     /note="immunoglobulin light chain variable region"
     V_region        91..424
     V_segment       91..387
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67578.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       388..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           85 a          154 c          125 g           98 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcact
       61 ctcctccttc actgcacagg gtctctctcc cagcctgtgc tgactcagtc gccctctgcc
      121 tctgcctccc tgggagcctc ggtcaagctc acctgcactc tgagcagtgg acacaggagc
      181 tacaccatcg cgtggcatca gcagcagcaa gggaaggccc ctcgatactt gatgtggctt
      241 aaaagtgatg gcagccacag caagggggac gggatccctg atcgcttctc aggctccagc
      301 tccggggctg agcgctacct caccatctcc aacctccagt ctgaggatga ggctgattat
      361 tattgtcaga cgtgggatat tggcatttgg gtgttcggcg gagggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001841             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:16482:16113
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001841
VERSION     KCWK01001841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16482:16113"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..416
                     /note="immunoglobulin light chain variable region"
     V_region        105..416
     V_segment       105..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67579.1"
                     /translation="DYYCQSADSSGNHWLF"
     J_segment       392..416
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>466
                     /gene="IGLC"
BASE COUNT          105 a          135 c          132 g           94 t
ORIGIN      
        1 acatgggggg ctgtggttct aggaggaaga gctctgggtg tctcaccatg acctggacca
       61 ctgttctgct cccctttctc actctctgca caggctctga ggcctcttat gagctgacac
      121 agccaccctc agtgccagtg tccccaggac agacggccag gatcacctgg tctggagaag
      181 aactggcaaa aaaatctgct cagtggttcc agcagaagcc aggccaggcc cctgtgttgg
      241 tgattcataa agacagtgag aggccctcag ggatccctga ccgattccct aggtccactc
      301 cagggacaaa agataccttg accagtaggg gggccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagca gtggtaatca ttggctattc ggcggaggga cccggcaaag
      421 cgtcctgggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001842             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:12582:14787
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001842
VERSION     KCWK01001842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12582:14787"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67580.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       389..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           87 a          145 c          134 g           95 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacagact ctgcggcctc ctatgatctg acgcagccac
      121 cctcgatttc agtgtcccca ggacagacgg ccaggctgac ctgcggggga gacaacattg
      181 gaagtgaagt tgtgaactgg taccagcaga agccaccgca ggcccctgtg ttggtcatct
      241 atgctgacag cgagcggccc tcagggatcc ctgagcgatt ctctggctcc aagtcaggga
      301 acacggccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga ccttaacagt catcatctct tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001843             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:21182:16756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001843
VERSION     KCWK01001843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21182:16756"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..403
                     /note="immunoglobulin light chain variable region"
     V_region        76..403
     V_segment       76..363
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>375
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67581.1"
                     /translation="DYYCDSWDTTGTHPVLF"
     J_segment       366..403
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        404..>441
                     /gene="IGLC"
BASE COUNT           86 a          142 c          115 g           98 t
ORIGIN      
        1 acatggggtg tctccaccat ggcctggact cctctctggc tcaccctcct cagtctttgc
       61 acaggttctg tggtttcctc tggcctgact caggaccctg cagtgtctgt ggccttggga
      121 cagactgtca ggatcacctg ccaaggagac agcctcagaa ccagttatgc aagctggtac
      181 cagcagaagc caggccaggc ccctgtcctg gtcgtctatg gtaacaacta ccggccctca
      241 gggatcccag agcgattctc tggctccaac tcaagaaaca cagcttcctt gaccatcact
      301 gggactcagg tggaagatga ggctgactat tactgtgact cctgggacac caccggtacc
      361 catcctgtgt tattcggagg agggacccgg gtgaccgtcc taggtcagcc caaggctgcc
      421 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001844             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13889:9982
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001844
VERSION     KCWK01001844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13889:9982"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67582.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          157 c          118 g          112 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tctttacatc ttcggtgctg
      421 ggacccggct cagcgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001845             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:11757:16138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001845
VERSION     KCWK01001845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:11757:16138"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    27..357
                     /note="immunoglobulin light chain variable region"
     V_region        27..357
     V_segment       27..313
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <285..>329
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67583.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       327..357
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        358..>395
                     /gene="IGLC"
BASE COUNT           78 a          122 c          103 g           92 t
ORIGIN      
        1 acatgggggg cacaggatcc tgggctcagg ctgccccgac tcagactccc tctgtgtccg
       61 ggtctcctgg acagtcggtc accatctcct gcactggaac cagcagtgat attgggtatt
      121 atcatgctgt gtcttggtac cagcatcatc caggcaaagc ccccaaactc atgatttatg
      181 aggtcaataa acggcccgca ggggtctctg atcgcttctc tggctccaag tctggcaaca
      241 cggcctccct gaccatctct gggctccaga ctgaggatga ggctgattat tactgtagct
      301 catatgcagg cagcaacagt ttattcttcg gaggagggac ccggctgacc gtcctaggtc
      361 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001846             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15396:9380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001846
VERSION     KCWK01001846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15396:9380"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67584.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           94 a          161 c          124 g          107 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gacgcagcca
      121 ccctccctgt ctgcatcccc gggagcaccg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gcagtaaaaa catgtactgg taccaacaga agccagggag cgctcccagg
      241 ttatttctgt actacaactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgatcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtatatgaca gtagtgctaa tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01001847             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10721:18648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001847
VERSION     KCWK01001847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10721:18648"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..432
                     /note="immunoglobulin light chain variable region"
     V_region        99..432
     V_segment       99..395
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67585.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       396..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           86 a          159 c          125 g          100 t
ORIGIN      
        1 acatgggagc agagccctga ggagtctgca ccatggcctg gaccccaatc ctcctcctcc
       61 tcctcactct cctccttcac tgcacagggt ctctctccca gcctgtgctg actcagtcgc
      121 cctctgcctc tgcctccctg ggagcctcgg tcaagctcac ctgcactctg agcagtggac
      181 acaggagcta caccatcgcg tggcatcagc agcagcaagg gaaggcccct cgatacttga
      241 tgtggcttaa aagtgatggc agccacagca agggggacgg gatccctgat cgcttctcag
      301 gctccagctc cggggctgag cgctacctca ccatctccaa cctccagtct gaggatgagg
      361 ctgattatta ttgtcagacg tgggatattg gcatttgggt gttcggcgga gggacccggc
      421 taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001848             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:18930:15734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001848
VERSION     KCWK01001848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18930:15734"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67586.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          150 c          122 g          113 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gttcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatgtt gggtattata acgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 caaactcatg atttatgacg tcattaagcg gccctcaggg gtttctgatc gcttctctgg
      301 ctccaagtct ggcgacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag aaataatttt ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001849             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:22633:3131
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001849
VERSION     KCWK01001849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22633:3131"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67587.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       401..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          152 c          114 g          115 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcatctcc tggagcatca gccagactca cctgcacctt gaacagtggc atcagtgttg
      181 gtaattacag gatattctgg taccaccaga agccagggag tcctccccgg tatcttctga
      241 actaccacac agactcagat attcaccagg gctctggagt ccccagccgc ttctctgggt
      301 ccaaggatgc ttcggccaat gcagggattt tactcatctc tggactccag tctgaggatg
      361 aggctgacta ttattgtatg atttggcaca acaatgctta ttgggtattc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001850             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:24905:8171
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001850
VERSION     KCWK01001850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24905:8171"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67588.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       392..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>464
                     /gene="IGLC"
BASE COUNT           90 a          144 c          133 g           97 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag actctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgttaac tggtaccagc agaagccacc gcaggcccct gtcctggtca
      241 tctatgctaa taacgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg gggcgttact agtgatcatc ccttattcgg aggagggacc cggctgaccg
      421 tccaaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001851             283 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:20450:20282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001851
VERSION     KCWK01001851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 283)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20450:20282"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..242
                     /note="immunoglobulin light chain variable region"
     V_region        13..242
     V_segment       13..208
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <170..>217
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67589.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       211..242
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        243..>283
                     /gene="IGLC"
BASE COUNT           58 a           86 c           83 g           56 t
ORIGIN      
        1 acatggggaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tcctggtcat
       61 ctatgctaat aacgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      121 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      181 tcaggtgtgg ggcgttacta gtgatcatcc cttattcgga ggagggaccc ggctgaccgt
      241 ccaaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001852             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:7236:13754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001852
VERSION     KCWK01001852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7236:13754"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67590.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           95 a          156 c          124 g          109 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aagagtgtca ccatctcctg
      181 ttctggaagc agctccaaca tcggaagtaa taatgtgtcc tggtaccagc acctcccagg
      241 aacagctccc aaactcctca tctattataa tgatcaacga ggctcaggtg tctctgaccg
      301 attctctggc tccaagtctg gcacgtcagc ctccctggcc atcagtgggc tccagaccga
      361 ggatgaggct gattattact gcgcagcgtg ggatgatagc ctgagtagtt acatcttcgc
      421 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01001853             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:20399:18262
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001853
VERSION     KCWK01001853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20399:18262"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67591.1"
                     /translation="DYYCGIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          156 c          118 g          107 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cacgggtggc atcaatgttg
      181 ctgactacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtggc attgggcaca gcagcggtga ttacatcttc gctgatggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001854             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:7003:6286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001854
VERSION     KCWK01001854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:7003:6286"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67592.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          154 c          122 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaacc cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001855             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:18055:3380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001855
VERSION     KCWK01001855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18055:3380"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67593.1"
                     /translation="DFYCQVWDIYVDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           87 a          142 c          135 g          104 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attgtaagtg aagttgtcaa ctggtaccag cagaggccac cgcaggcccc tgtgctggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgacttttat
      361 tgtcaggtgt gggacattta tgttgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001856             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:20857:15868
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001856
VERSION     KCWK01001856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:20857:15868"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67594.1"
                     /translation="DYYCQSTDTSGNYIF"
     J_segment       372..408
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT          103 a          131 c          115 g           97 t
ORIGIN      
        1 acatggggaa gagctctggg tgtctcacca tgacctggac cactgttctg ctcccctttc
       61 tcactctctg cacaggctct gaggcctcct atgagctgac acagccaccc tcagtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggagg aatactggca aaaaaatatg
      181 ctcagtggtt gcagcagaag ccaggccagg cccctgtgtt ggtaatatat aaagacagtg
      241 agaggccctc agggatccct gagcgattct ctagttccag ttcagggaca acagttgcct
      301 tgaccatcag tggggcccag gcagaagatg aggctgacta ttactgtcaa tcaacagaca
      361 ccagtggtaa ttacatcttc ggtgctggga cccggctcaa cgtcctaggt cagcccaagg
      421 cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001857             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:5663:18097
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001857
VERSION     KCWK01001857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5663:18097"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67595.1"
                     /translation="DYYCQVWDNSNKYAIF"
     J_segment       396..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          144 c          134 g           96 t
ORIGIN      
        1 acatggggct gactttggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactttacag gctctgcggc ctcctatgga ttgactcagc
      121 cacgctcagt gtccgtgtcc ccgggacaga cggccaggat cacctgtggg ggagacaaga
      181 ttggaagtaa aagtgtacac tggtaccagc agaggccacc gcaggcccct gtactggtca
      241 tctatgttga tggcgaccgg ccctcaggga tccctgaacg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgagtct gactattact
      361 gtcaggtatg ggataatagt aataaatacg cgatcttcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001858             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:8380:24563
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001858
VERSION     KCWK01001858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8380:24563"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..381
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67596.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       393..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          148 c          134 g           96 t
ORIGIN      
        1 acatgggggg tctgggtctc aggaggcagc attgacggtg cctcagccat ggcctggacc
       61 cttctcctcc tcggcctcct cgctcactgc acaggctctg cgacctcctt tgagctgact
      121 cagccaccct cggtgtcagc ggcctcagga cagacggcca ggatcacctg tgggggagac
      181 aacattggaa ttaaatttgt ccactggtac cagcagaagc cagcgcaggc ccctgtgaag
      241 gtcatctatg ctgatgacaa acggccctca gggatccctg agagattctc tggctccaat
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tcctgtcagg tgtgggacag tgagactgat cattacatct tcggtgctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01001859             274 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:4563:16838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001859
VERSION     KCWK01001859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 274)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 274)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4563:16838"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..236
                     /note="immunoglobulin light chain variable region"
     V_region        8..236
     V_segment       8..200
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <164..>208
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67597.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       201..236
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        237..>274
                     /gene="IGLC"
BASE COUNT           60 a           81 c           80 g           53 t
ORIGIN      
        1 acatggggtc cactggtacc agcagaagcc agcacaggcc cctgtggtag tcatctatgc
       61 tgataacaaa cggccctcag ggatccctga gcgactctct ggctccaact cagggaatat
      121 tgccaccctg accatcagca gggtcgaggc cggggatgag gcagactatt actgtcaggt
      181 gtgggacagt agtagtaaat gggtattcgg cggagggacc cggctaaccg tcctaggtca
      241 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001860             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:23078:4744
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001860
VERSION     KCWK01001860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23078:4744"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67598.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          156 c          124 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca tctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaagtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001861             353 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:11958:14563
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001861
VERSION     KCWK01001861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 353)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11958:14563"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..315
                     /note="immunoglobulin light chain variable region"
     V_region        8..315
     V_segment       8..278
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>287
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67599.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       279..315
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        316..>353
                     /gene="IGLC"
BASE COUNT           76 a          107 c           94 g           76 t
ORIGIN      
        1 acatgggggg agcatcggcc agactcccct gcaccctgac cagtgacctc agctttggta
       61 gtaaaaacat gtattggtac cagcagaagc cagggagcgc tcccaggtca ttcctctact
      121 actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc tctggctcca
      181 aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct gaggacgagg
      241 ccgactatta ctgtcaggtg tatgacagta gtgctaatgt gttattcgga ggagggaccc
      301 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001862             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:21004:6971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001862
VERSION     KCWK01001862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21004:6971"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67600.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       412..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          161 c          124 g          108 t
ORIGIN      
        1 acatgggggc agcttcaact gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct cccagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gacgatagcc tgcgcggcta tatcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001863             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:5240:19717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001863
VERSION     KCWK01001863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5240:19717"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67601.1"
                     /translation="DYYCAAGYGSGSDWQWVF"
     J_segment       398..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           94 a          153 c          130 g           95 t
ORIGIN      
        1 acatggggat cctggcttca gaagcagcat ctgggacatg tcagccatgg cctggacgcc
       61 tctcctcctc agcctcctcg ctcactgcac aggctctgtg gcctcctatg acctgactca
      121 gccaccctca gtgtcggtgt ccccaggaca gacagccatc atcacctgct ctggaaatga
      181 attggggaat gtatatgctt cctggtacca ccagaagcca ggccaggccc ctgtattggt
      241 catctacaaa gataccaacc ggccctcagg gatccctgag cgattctctg gctccaactc
      301 agggaacacg gccaccctga ccatcagcag ggtcgaggct ggggatgaag ccgactatta
      361 ctgtgctgca ggctatggca gtgggagcga ctggcagtgg gtattcggcg gggggacccg
      421 gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001864             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:18832:16324
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001864
VERSION     KCWK01001864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18832:16324"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67602.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       402..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          151 c          120 g          114 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggttcaggct gccccaactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat aacgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 ccaaactcat aatttttgac gtcattaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcgacacg gcctccctga ccatctctgg gctccgggct gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gaaataattt tttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001865             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:10752:11441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001865
VERSION     KCWK01001865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10752:11441"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67603.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       398..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           85 a          156 c          118 g          114 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaagct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtcttat gatgctgtgt cttggtacca acagcctcca ggcaaagccc
      241 cccaactcat aatttttgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgctgctca tatgtaggca gcaacactta catcttcgat gttgggaccc
      421 ggctcaccgt cctaggtcag tccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01001866             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:11740:9528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001866
VERSION     KCWK01001866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11740:9528"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67604.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          156 c          121 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc aacgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca actccaacat cggaagttat aatgtgtcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagtggtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001867             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:16738:18439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001867
VERSION     KCWK01001867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16738:18439"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67605.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          141 c          136 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga cactgcggcc tcctatgatc tgactcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccagggtc acctgtgggg gagacaacat
      181 cggaggtgaa gttgtgaatt ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat agcgagcggc cctcagggat cccggagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccgga gatgaggctg actattactg
      361 tcaggtgtgg gaccttaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001868             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:23352:11909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001868
VERSION     KCWK01001868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23352:11909"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..439
                     /note="immunoglobulin light chain variable region"
     V_region        93..439
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67606.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>479
                     /gene="IGLC"
BASE COUNT           92 a          162 c          110 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagtagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtcctg ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001869             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:26833:12153
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001869
VERSION     KCWK01001869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:26833:12153"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..433
                     /note="immunoglobulin light chain variable region"
     V_region        112..433
     V_segment       112..397
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67607.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       401..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           92 a          147 c          135 g           97 t
ORIGIN      
        1 acatggggct gccctgtctg ggtctcagga ggcagcattg acggtgcctc agccatggcc
       61 tggacccttc tcctcctcgg cctcctcgct tactgcacag actctgcgac ctcctatgaa
      121 ttgactcagt cgccctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg
      181 ggagacgaca ttggaactaa aactgtgcac tggtaccaac agaagccacc gcagggccct
      241 ctattggtca tctttgctga tagtagacgg ccctcaggga tccctgagcg attctctggc
      301 tccaactcag ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct
      361 gactattact gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg
      421 ctaagcgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001870             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17138:20541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001870
VERSION     KCWK01001870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17138:20541"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..380
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67608.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       392..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          147 c          133 g           97 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctccttt gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaat taaatttgtc cactggtacc agcagaagcc agcgcaggcc cctgtgaagg
      241 tcatctatgc tgatgacaaa cggccctcag ggatccctga gagattctct ggctccaatt
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 cctgtcaggt gtgggacagt gagactgatt attacatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01001871             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:14978:6875
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001871
VERSION     KCWK01001871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14978:6875"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67609.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           82 a          146 c          138 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tccgtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tcgaagtgaa gttgtgaact ggtaccagca gaagccagcg caggcccctg tgttggtcat
      241 ctttgctgat accgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tccgcggggt cgaggccggg gatgaggctg acttttactg
      361 tcaggtgtgg gacattcgta gtgatcgtcc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001872             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:19847:10884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001872
VERSION     KCWK01001872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19847:10884"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..402
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67610.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       406..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          155 c          122 g          109 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaataa tgtgtcctgg taccagcacc tcccaggaac
      241 agctcccaaa ctcctcatct attataatga tcaacgaggc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcgtggga tgatagcctg agtagttaca tcttcgctgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01001873             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:6742:13905
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001873
VERSION     KCWK01001873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6742:13905"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..254
                     /note="immunoglobulin light chain variable region"
     V_region        96..254
     V_segment       96..217
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <182..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67611.1"
                     /translation="DYHCQVYDSSANVLF"
     J_segment       218..254
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           54 a          102 c           70 g           66 t
ORIGIN      
        1 acatgggctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
       61 ctccctgtct gcatccccgg gagcatcggc cagactcccc aatcgagtct ctggctccaa
      121 ggagacctca aataacacag cgtttttgct catctctggc ctccagcctg aggacgaggc
      181 cgattatcac tgtcaggtgt atgacagtag tgcaaatgtg ttattcggag gagggacccg
      241 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001874             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:8156:6547
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001874
VERSION     KCWK01001874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8156:6547"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67612.1"
                     /translation="NFYCQVWDIRSDRPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           81 a          147 c          139 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtccgtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttcgaagtga agttgtgaac tggtaccagc tgaagccagc gcaggcccct gtgctggtca
      241 tctttgctga taccgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atccgcgggg tcgaggccgg ggatgaggct aacttttact
      361 gtcaggtgtg ggacattcgt agtgatcgtc cgctattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001875             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:20339:4861
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001875
VERSION     KCWK01001875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20339:4861"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67613.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          162 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctata ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001876             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:9325:9764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001876
VERSION     KCWK01001876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9325:9764"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67614.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          159 c          126 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtggtg actcagccac
      121 cctccctgtc cgcatccccg ggagcatcgg ccagactccc ctgcactctg agtagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgtt ctaccagtcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgcaaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001877             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:14058:20475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001877
VERSION     KCWK01001877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14058:20475"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67615.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       410..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          153 c          126 g          113 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacg atctcctgca
      181 gtgggagcaa ctccaacatt ggatattatt atgtgcagtg gtaccagcag cttccaggaa
      241 cggcccccaa actcctcatc tatgaaaata ataagcgacc ctctggggtt tctgatcgat
      301 tctctggctc ccagtctggt acctcagcct ccctgaccat cactggactc cagtctgagg
      361 atgaggctga ttattactgc cactcctatg acagcagttt gagtggtgtc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001878             285 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:22456:20759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001878
VERSION     KCWK01001878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 285)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22456:20759"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..247
                     /note="immunoglobulin light chain variable region"
     V_region        5..247
     V_segment       5..212
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <175..>219
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67616.1"
                     /translation="DYYCSSYGGSNTLFF"
     J_segment       217..247
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        248..>285
                     /gene="IGLC"
BASE COUNT           60 a           86 c           71 g           68 t
ORIGIN      
        1 acatgggatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc ccccaaactc
       61 atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc tggctccaag
      121 tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga ggctgattat
      181 tactgcagct catatggagg cagcaatact ttattcttcg gaggagggac ccggctgacc
      241 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001879             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:15791:12764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001879
VERSION     KCWK01001879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15791:12764"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67617.1"
                     /translation="DYHCQVWDINSHHLLF"
     J_segment       391..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          142 c          138 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag tctctgcggc ctcctatgat ctgacgcagc
      121 caccctcgat ttcagtgtcc ccaggacaga cggccaggct gacctgtggg ggagacaaca
      181 ttggaagtga ggttgtcaac tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tctatgctga cagcgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgagc atcagcgggg tcgaggccgg ggatgaggct gactatcact
      361 gtcaggtgtg ggacattaat agtcatcatc tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001880             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:4351:13576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001880
VERSION     KCWK01001880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:4351:13576"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67618.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          158 c          119 g          112 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacgtacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg ggtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tctttacatc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001881             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:4840:13994
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001881
VERSION     KCWK01001881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:4840:13994"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67619.1"
                     /translation="DYYCQVWDSSSDHYIF"
     J_segment       389..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          143 c          131 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg tagacaacat
      181 tggaagtaaa aatgtgcact ggtaccagca gaagccaccg caggcccctg tgctggtcat
      241 ctattatgat agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtgatcatta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01001882             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:20773:12784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001882
VERSION     KCWK01001882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20773:12784"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..432
                     /note="immunoglobulin light chain variable region"
     V_region        112..432
     V_segment       112..393
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67620.1"
                     /translation="DYFCQVWDSGSDHYIF"
     J_segment       399..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>474
                     /gene="IGLC"
BASE COUNT           86 a          153 c          134 g          101 t
ORIGIN      
        1 acatggggct gccctgtctg ggtctcagga ggcagcattg acggtgcctc agccatggcc
       61 tggacccttc tcctcctcgg cctcctcgct cactgcacag gctctgcgac ctcctatgag
      121 ttgactcagc caccctcggt gtcagcggcc tctggacaga cggccaggat cacctgtggg
      181 ggagacaaca ttggaactac atatgtgcac tggtaccagc agaagccacc acaggcccct
      241 gtgcaggtca tctttgctga tagcaaacgg ccctcagggg tccctgaccg attctctggc
      301 tccaactcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct
      361 gactatttct gtcaggtgtg ggacagtggt agtgatcatt acatcttcgg tgttgggacc
      421 cggctcaccg tcttaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01001883             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:21521:10683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001883
VERSION     KCWK01001883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21521:10683"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67621.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          148 c          128 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tatactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001884             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:21817:14753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001884
VERSION     KCWK01001884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21817:14753"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..440
                     /note="immunoglobulin light chain variable region"
     V_region        110..440
     V_segment       110..405
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67622.1"
                     /translation="DYYCSSYEGRNNFLF"
     J_segment       407..440
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           91 a          150 c          122 g          115 t
ORIGIN      
        1 acatggggag tgctgggatc tcaggaggca gcgctctcag gacttctcca ccatggtctg
       61 ggctctgctc ctcctcaccc tcctcactca gggcacagga tcctgggttc aggctgcccc
      121 gactcagcct ccctctgtgt ccgggtctcc tggacagtcg gtcaccatct cctgcactgg
      181 aaccagcagt gatattgggt attataatgc tgtgtcttgg taccaacagc atccaggcaa
      241 agcccccaaa ctcatgattt atgacgtcat taagcggccc tcaggggtct ctgatcgctt
      301 ctctggctcc aagtctggca acacggcctc cctgaccatc tctgggctcc aggctgagga
      361 tgaggctgat tattactgca gctcatatga aggcagaaat aattttttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001885             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:19373:11932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001885
VERSION     KCWK01001885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19373:11932"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67623.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       392..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          102 a          137 c          122 g          102 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagg tgacacagtc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctccg gagcaatact
      181 ggcaaataat tatgctcagt ggttccagca gaagccagac caggcccctg tgttggtgat
      241 atataaagac actgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacagtt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagtt gacagcagtg cccatcatcc attattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001886             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:23024:13764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001886
VERSION     KCWK01001886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23024:13764"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..387
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67624.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       388..419
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           93 a          139 c          126 g           99 t
ORIGIN      
        1 acatggggtg ggctcagaag cagagctctg gggtgtctcc accatggcct ggactcctct
       61 ctggctcacc ctcctcagtc tttgcacagg ttctgtggtt tcttctgagc tgactcagga
      121 ccctgcagtg tctgtggcct tgggacagac agtcaggatc acctgccaag gagacagcct
      181 cagaagtcat tatgcaagtt ggtaccagca gaagccaggc caggccccta tactggtcgt
      241 ctatggtaac aattaccggc cctcagggat cccagagcga ttctctggct ccagtacacg
      301 aaacacagct tccttgacca tcactggggc tcaggtggaa gatgaggctg actattactg
      361 tgactcctgg gacagccgcg gaacccaatt cggaggaggg acccggctga ccgtcctagg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001887             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:17167:7995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001887
VERSION     KCWK01001887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17167:7995"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67625.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          158 c          123 g          106 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtcta ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaagtc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catatacagg catcaacagt tacatcttcg gtggtgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001888             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20725:13781
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001888
VERSION     KCWK01001888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20725:13781"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67626.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          143 c          134 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccaaca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgaccga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgcggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ctgatcatcc ggtgttgttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001889             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:18336:10950
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001889
VERSION     KCWK01001889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18336:10950"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..394
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67627.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       408..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           87 a          157 c          122 g          110 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccccga
      121 ctcagactcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tgttgggtat tatcatgctg tgtcttggta ccagcatcat ccaggcaaag
      241 cccccaaact catgatttat gaggtcaata aacggcccgc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag actgaggatg
      361 aggctgatta ttactgcagc tcatatgcag gcagcaacgc tttattcttc ggacgaggga
      421 cccgcctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001890             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:19850:10934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001890
VERSION     KCWK01001890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19850:10934"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..398
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67628.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       400..435
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           94 a          152 c          117 g          110 t
ORIGIN      
        1 acatgggggc tctggagcca gggatccctt ccaatatcag caccatggcc tggactctgc
       61 tcctcctcca gttcctcctc acttgctgcc cagggtccaa ttctcaggct gtagtgactc
      121 aggagccctc aatgactgtg tccccaggag ggacagtcac tctcacctgt gcttccagca
      181 ctggagcagt caccagtggt cactctccac actggttcca gcagaaacct ggacaagccc
      241 ccaagacact gatttataat acaaactaca gacactcctg gactcctgcc cggttctcag
      301 gctccctcct tgggggtaaa gctgccctga cactgtcagg tgcgcagcct gaggatgagg
      361 ctgagtatta ttgtttactg tactatagtg gtgctcagct gttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001891             308 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:26363:13338
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001891
VERSION     KCWK01001891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 308)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 308)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:26363:13338"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..270
                     /note="immunoglobulin light chain variable region"
     V_region        8..270
     V_segment       8..233
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <195..>242
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67629.1"
                     /translation="DINCHSADSSGNHWVF"
     J_segment       234..270
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        271..>308
                     /gene="IGLC"
BASE COUNT           73 a           81 c           87 g           67 t
ORIGIN      
        1 acatgggctg ttctggagaa acactggcaa aaaaatatgg tcagtggttc cagcagaagc
       61 caggccaggc ccctgttgtg gtgatatata aggacagtga gaggccctca gggatccctg
      121 agcgattctc taggtccatt tcagggacaa taattacctt gaccatctgt ggggccccgg
      181 cagaagatga ggctgacatt aactgtcatt cagcagacag cagtggtaat cattgggtct
      241 tcggcggagg gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      301 tcttcccg
//
LOCUS       KCWK01001892             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:4588:8411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001892
VERSION     KCWK01001892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:4588:8411"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67630.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          142 c          133 g           93 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgaa ttgactcagt
      121 caccctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa aactgtgcac tggtaccaac agaagccacc gcagggccct gtattggtca
      241 tctttgctga tagtagacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001893             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:13360:11845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001893
VERSION     KCWK01001893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13360:11845"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..387
                     /note="immunoglobulin light chain variable region"
     V_region        63..387
     V_segment       63..349
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <312..>359
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67631.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       351..387
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        388..>425
                     /gene="IGLC"
BASE COUNT           83 a          137 c          114 g           91 t
ORIGIN      
        1 acatgggggc ctggactttt ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg
       61 cctcctatga tctgactcag ccaccctcgg tgtcagtgtc cccaggacag acggccagga
      121 tcacctgtgg gggagacaac attggaagtc aaagtgtaca ctggtaccag cacaagccac
      181 cgcaggcccc tgttctgctc atcttttatt ataccgaacg gccctcagga atccctgagc
      241 gattctctgg ctccaaatca gggaacaccg ccaccctgac catcagcggg gtcgaggccg
      301 gggatgaggc tgactattac tgtcaggtgt gggacacaac tattgatcac ggcttgttcg
      361 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      421 tcccg
//
LOCUS       KCWK01001894             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:20250:6329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001894
VERSION     KCWK01001894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20250:6329"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..388
                     /note="immunoglobulin light chain variable region"
     V_region        58..388
     V_segment       58..344
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <316..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67632.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       358..388
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           81 a          138 c          107 g          100 t
ORIGIN      
        1 acatgggggg ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag
       61 gctgccccga ctcagactcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc
      121 tgcactggaa ccagcagtga tattgggtat tatcatgctg tgtcttggta ccagcatcat
      181 ccaggcaaag cccccaaact catgatttat gaggtcaata aacggcccgc aggggtctct
      241 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag
      301 actgaggatg aggctgatta ttactgtagc tcatatgcag gcagcaacag tttattcttc
      361 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      421 ttcccg
//
LOCUS       KCWK01001895             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:4756:6581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001895
VERSION     KCWK01001895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:4756:6581"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..379
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67633.1"
                     /translation="DYYCQVWDSSTRYAVF"
     J_segment       386..416
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           87 a          144 c          132 g           91 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacccttc tcctcctcgg
       61 cctcctcgct tactgcacag gctctgcgac ctcctatgag ctgactcagc caccctcatt
      121 gccagcggcc tcaggacaga cggccaggat cgcctgtggg ggagacagca ttggaagtga
      181 aaatgtgttc tggtaccagc agaagccacg gcaggcccct gtcctggtca tctatggtga
      241 tacgaaacgg ccctcaggga tccctgagcg attctctggc tccatctctg ggaacaccgc
      301 caccctgacc atcaacaggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg
      361 ggacagtagt actagatacg cggttttcgg cggagggacc cggctaaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001896             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:12574:9759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001896
VERSION     KCWK01001896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12574:9759"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67634.1"
                     /translation="DYYCQSYDRSLNAILF"
     J_segment       414..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           93 a          154 c          127 g          111 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtatctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggagatt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc cagactcctc atctatgaaa atgataagcg accctcaggg gcttctaatc
      301 gattctctgg ctcccagtct ggtacctcag cctcgctgac cataagtgga ctccagtctg
      361 aggatgaggc tgactattac tgccagtctt atgacagaag cttgaatgct attttattcg
      421 gaggcgggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001897             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:20083:3777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001897
VERSION     KCWK01001897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20083:3777"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67635.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       403..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           84 a          162 c          126 g           99 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtggt gactcagtcg
      121 tcctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcggtggg
      181 cacagcgact acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggtatttg
      241 atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctga tcgcttctcc
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggagact ggcattcagg tgttcggcgg agggacccgg
      421 ctaaccgtcc taggtcatcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001898             323 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:12949:15190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001898
VERSION     KCWK01001898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 323)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12949:15190"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..285
                     /note="immunoglobulin light chain variable region"
     V_region        8..285
     V_segment       8..248
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <213..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67636.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       249..285
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>323
                     /gene="IGLC"
BASE COUNT           68 a          101 c           81 g           73 t
ORIGIN      
        1 acatgggcag cggtggcatc aatgttgctg cctaccacat acactggtac cagcagaagc
       61 cagggagtcc cccccggtat cttctgagtt acaaatcaga ctcagataag ggccagggct
      121 ctggagtccc cagccgcttc tctggatcca aaaatgcttc aacgaacgca ggcatttttc
      181 acatctctgg gctccagtct gaggatgagg ctgactattt ctgtgccatt ggacacagca
      241 gcggtcctta catcttcggt gctgggaccc ggctcaccgt cctaggtcag cccaaggctt
      301 cccccacggt cactctgttc ccg
//
LOCUS       KCWK01001899             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:20123:6294
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001899
VERSION     KCWK01001899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20123:6294"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..278
                     /note="immunoglobulin light chain variable region"
     V_region        8..278
     V_segment       8..239
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <206..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67637.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       241..278
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>316
                     /gene="IGLC"
BASE COUNT           68 a           88 c           80 g           80 t
ORIGIN      
        1 acatgggggc atcagtgttg gtaattacag gatattctgg taccaccaga agccagggag
       61 tcctccccgg tatcttctga actaccacac agactcagat attcatcagg ggtctggagt
      121 ccccagccgc ttctctggat ccaaagatgc ttcggccaat gcagggattt tactcatctc
      181 tggactccag tctgaggatg aggctgacta ttactgtatg atttggcaca acaatgctta
      241 ttgggttttc ggcggaggga cccggctaac cgtcctaggt cagcccaagg ctgccccctc
      301 ggtcactctc ttcccg
//
LOCUS       KCWK01001900             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:9590:3327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001900
VERSION     KCWK01001900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9590:3327"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..394
                     /note="immunoglobulin light chain variable region"
     V_region        76..394
     V_segment       76..362
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67638.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       363..394
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>432
                     /gene="IGLC"
BASE COUNT           87 a          136 c          115 g           94 t
ORIGIN      
        1 acatggggtg tctccaccat ggcctggact cctctctggc tcaccctcct cagtctttgc
       61 acaggttcta tggtttcttc tgagctgact caggaccctg cagtgtctgt ggccttggga
      121 cagacagtca agattacctg ccaaggagac agcctcagaa gctcttatgc aagctggtac
      181 caacagaggc caggccaggc ccctgtgctg gtcgtctatg gtaacagcaa ccggccctca
      241 gggatcccag agcgattctc tggctcctac tcacgaaaca cagcttcctt gaccatcact
      301 ggggctcagg tggaagatga ggctgactat tactgtgact cctgggacag cagcggaacc
      361 caattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      421 actctcttcc cg
//
LOCUS       KCWK01001901             340 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:9409:8066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001901
VERSION     KCWK01001901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 340)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9409:8066"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..302
                     /note="immunoglobulin light chain variable region"
     V_region        8..302
     V_segment       8..265
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <230..>274
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67639.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       266..302
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        303..>340
                     /gene="IGLC"
BASE COUNT           71 a          104 c           84 g           81 t
ORIGIN      
        1 acatggggcc agactcagct gcaccttgag cagtggcaat gttggtagtt acagcatatt
       61 ctggtaccag cagaagccag ggagtcctcc ccggtacctt ctttactact actcagactc
      121 aagtaaccac caggactctg gagtccccag ccgcttctct ggatcgaaag atgcttcagc
      181 caatgcaggg cttttactga tctctgggct ccagtctgaa gatgaggctg actattactg
      241 tgccacatgg cacagcagcg cttcttacat cttcggtggt gggacccggc tcaccgtcct
      301 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01001902             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:19232:15509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001902
VERSION     KCWK01001902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19232:15509"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67640.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       402..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          150 c          121 g          114 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcaggaca caggatcctg ggttcaggct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatgt tgggtattat aacgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 ccaaactcat gatttatgac gtcattaagc ggccctcagg ggtttctgat cgcttctctg
      301 gctccaagtc tggcgacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gaaataattt tttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001903             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:11571:6401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001903
VERSION     KCWK01001903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11571:6401"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..404
                     /note="immunoglobulin light chain variable region"
     V_region        74..404
     V_segment       74..367
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <323..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67641.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       368..404
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>442
                     /gene="IGLC"
BASE COUNT           86 a          142 c          123 g           91 t
ORIGIN      
        1 acatgggatg tcagccatgg cctggacgcc tctcctcctc agcctcctcg ctcactgcac
       61 aggctctgtg gcctcctatg agctgactca gccaccctca gtgtcggtgt ccccaggaca
      121 gacagccagc atcacctgct ctggaaataa attggggaat gtatatgctt actggttcca
      181 gcagaagcca ggccaggccc ctgtagtggt catctacaaa gataccaacc ggccctcagg
      241 gatccctgag cgattctctg gctccgactc agggaacacg gccaccctga ccatcagcag
      301 ggtcgaggct ggggatgagg ccgactattt ttgtgctgca gcctatggca gtggcagcag
      361 ctggcagtgg gtattcggcg gagggacccg gctaatcgtc ctaggtcagc ccaaggctgc
      421 cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001904             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:20431:11261
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001904
VERSION     KCWK01001904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20431:11261"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67642.1"
                     /translation="DYYCQVWDISSDHVLF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          139 c          140 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctccgcggcc tcctttgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa cttgtgaact ggtaccaaca gaggccaccg caggcccctg tgctggtcat
      241 gtatgctgat gacgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gagtacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattagta gtgatcatgt gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001905             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:2375:15643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001905
VERSION     KCWK01001905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:2375:15643"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..399
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67643.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       401..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           86 a          162 c          119 g          109 t
ORIGIN      
        1 acatgggggt ggcctcagag gtagccgtgt ccaccatggc cctgactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgactcag ccaccctccc
      121 tgtctgcatc cccgggagca tcggccagac tcccctgcac cctgagcagt gacctcagtg
      181 ttggtagtaa aaacatgtac tggtaccagc agaagccagg gagcgctccc aggttattcc
      241 tgtactacta ctccgactca gacaagcagc tgggacctgg ggtccccaat cgagtctctg
      301 gctccaagga gacctcaagt aacacagcgt ttttgctcat ctctgggctc cagcctgagg
      361 acgaggccga ttatttctgc cagctgtttg acagtagtgt tgtgttcttc ggaggaggga
      421 cccgactgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001906             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:17459:14067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001906
VERSION     KCWK01001906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17459:14067"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67644.1"
                     /translation="DYYCSSYAGSNTFVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           84 a          158 c          124 g          109 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata attatgtctc ctggtaccaa cagtctccag gcacagcccc
      241 caaactcgtg atttttgagg tcaataaacg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagcctg aggacgaggc
      361 tgattattac tgcagctcat atgcaggcag caacactttc gtgttgttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001907             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:16062:4593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001907
VERSION     KCWK01001907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16062:4593"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..365
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <329..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67645.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       369..401
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>439
                     /gene="IGLC"
BASE COUNT           90 a          138 c          123 g           88 t
ORIGIN      
        1 acatggggac ggtgcctcag ccatggcctg gacccttctc ctcctcggcc tcctcgctta
       61 ctgcacaggc tctgcgacct cctatgaact gactcagtca ccctcagtgt cagcggcctc
      121 aggacagccg gccaggatca cctgtggggg agacaacatt ggaattaaaa ctgtacactg
      181 gtaccagcag aagccaccgc agggccctgt attggtcatc tttgctgata gtaagcggcc
      241 cacagggatc cctgagcgat tctctggctc caactcaggg aacaccgcca ccctgaccat
      301 cagcagggtc gaggccgggg atgaggctga ctattactgt caggtgtggg acagtagtag
      361 taaatggata ttcggcgggg ggacccggct aaccgtccta ggtcagccca aggctgcccc
      421 ctcggtcact ctcttcccg
//
LOCUS       KCWK01001908             375 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:18153:4119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001908
VERSION     KCWK01001908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 375)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18153:4119"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..337
                     /note="immunoglobulin light chain variable region"
     V_region        13..337
     V_segment       13..300
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>309
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67646.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       304..337
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        338..>375
                     /gene="IGLC"
BASE COUNT           78 a          109 c          112 g           76 t
ORIGIN      
        1 acatgggcgg cctcctatga tctgactcag gcaccctcga tttcagtgtc ccccggacag
       61 acggccagga tcacctgtgg gggagacaac attggaagtg aagttgtgaa ctggtaccag
      121 cagaagccac cgcaggcccc tgtgttggtc atgtatgctg atagcgagcg gccctcaggg
      181 atccctgagc gattctctgg ctccaaatca gggaacacgg ccaccctgac catcagcggg
      241 gtcgaggccg gggatgaggc tgactattac tgtcaggtgt gggacatgaa tagtcatcat
      301 ctattattcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      361 gtcactctct tcccg
//
LOCUS       KCWK01001909             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:8328:10197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001909
VERSION     KCWK01001909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:8328:10197"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..267
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67647.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       272..306
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           71 a          104 c           85 g           84 t
ORIGIN      
        1 acatgggagt cagactcagc tgcaccttga gcagtggcat caatgttggt tcttacacca
       61 tattctggta ccagcagaag ccagggagtc ctccccggtt ccttctgtac tactactcag
      121 actcaaataa tcaccagggc tctggagtcc ccagccgctt ctctggatcc aaagatgctt
      181 cagccaatgc agggctttta ctgatctctg ggctccagtc tgaagatgag gctgactatt
      241 actgtgccat gtggcacagc agcgcttatg ccttattcgg aggagggacc cggctgaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001910             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:22709:10696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001910
VERSION     KCWK01001910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:22709:10696"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67648.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       397..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           82 a          155 c          126 g          106 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcatctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccaatctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagcattggc aacagctatg tgtactggtt ccagcagcgg ccgggcagcg tccccactat
      241 tgtgatttac aaagatgacc aaagaccctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctgga ctgaagtctg gggacgaggc
      361 tgactattac tgtcagtctt ttgacagcag cagtgtctta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001911             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:21885:5813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001911
VERSION     KCWK01001911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21885:5813"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..227
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67649.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       228..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           72 a           84 c           87 g           58 t
ORIGIN      
        1 acatgggggc ggagacaaca ttggaattaa aaatgtccac tggtaccagc agaagccagc
       61 acaggcccct gtggtagtca tctatgctga taacaaacgg ccctcaggga tccctgagcg
      121 actctctggc tccaactcag ggaatattgc caccctgacc atcagcaggg tcgaggccgg
      181 ggatgaggca gactattact gtcaggtgtg ggacagtagt agtaaatggg tattcggcgg
      241 agggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01001912             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:28879:9327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001912
VERSION     KCWK01001912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:28879:9327"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..421
                     /note="immunoglobulin light chain variable region"
     V_region        91..421
     V_segment       91..382
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67650.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       391..421
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           90 a          151 c          114 g          104 t
ORIGIN      
        1 acatgggagg aggcagcact caggacagtc tccagcatgg cctggtctct ccttctcact
       61 ctgctggttc actgcacagg gtcctgggcc cagtctgtgc tgacgcagcc gccctcagca
      121 tctggggccc ccggacagag ggtcaccatc tcctgcatta gcagcagctc caacatcggg
      181 gcggcttatt atgtatcctg gtaccaacag ttcccaggaa cagcccccaa actcctcatc
      241 tttgaaaata ataagcgacc ctcaggggtt tctgaccgat tctctggctc caagtctggt
      301 ccctcagcct ccctgaccat cactggactc caatctgagg atgaggctga ttattactgt
      361 ttagcatggg ataccagcct gaattggatc ttcggcggag ggacccgcct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001913             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:16023:9356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001913
VERSION     KCWK01001913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16023:9356"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67651.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          149 c          116 g          109 t
ORIGIN      
        1 acatgggggg agtcagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001914             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:16044:11368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001914
VERSION     KCWK01001914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16044:11368"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67652.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           92 a          161 c          116 g          111 t
ORIGIN      
        1 acatggggca ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgttgcct accacataca ctggtaccag cagaagccag ggagtccccc ccggtatctt
      241 ctgaggtaca aatcagactc agataagggc cagggcgctg gagtccccag ccgcttctct
      301 ggatccaata atgtttcagc gaacacaggg attttacgca tctctggcct ccagtctgag
      361 gatgaggctg actattactg tgccattggg cacagcagcg gtccttacat cttcggtgct
      421 gggacccgtc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01001915             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:4774:18290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001915
VERSION     KCWK01001915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:4774:18290"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    60..408
                     /note="immunoglobulin light chain variable region"
     V_region        60..408
     V_segment       60..371
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67653.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       374..408
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           83 a          153 c          107 g          103 t
ORIGIN      
        1 acatgggctg gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc
       61 agcctgtgct gacccagcca acctccctct cagcatctcc gggagcatca gccagactca
      121 actgcacctt gagcagtggc gtcaatgtgg gtagttacag catattctgg taccagcaga
      181 agccagggag tcctccccgg taccttctgt actaccagtc agactcaagg aagcaccagg
      241 gctctggagt ccccagccgc ttctctggat ccaaagatgc ttcagccaat gcagggctgt
      301 tactgatctc tgggctccag tctgaagatg aggctgacta ttactgtgcc ctatggcaca
      361 gcagcgcttc ttgcatcttc ggtggtggga cccggctcac cgtcctaggt cagcccaagg
      421 cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01001916             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:6907:16846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001916
VERSION     KCWK01001916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6907:16846"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67654.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaataccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001917             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:20281:9252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001917
VERSION     KCWK01001917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20281:9252"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67655.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       405..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           88 a          153 c          127 g          112 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc tccttctcac tctgctgctt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagc atctggggcc cccgggcaga gggtcaccat ctcctgctct
      181 gggagcagct ccaacatcgg ggcgggtttt tatgtatcct ggtaccagca gttcccagga
      241 acagccccca aactcctcat ctttgaaaat aataagcgac cctcaggggt ttctgaccga
      301 ttctctggct ccaagtctgg ttcctcagcc tccctgacca tcactggact ccaatctgag
      361 gatgaggctg attattattg ttcatcatgg gaaagcagcc tgaattgggt attcggcgga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001918             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:12699:8930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001918
VERSION     KCWK01001918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12699:8930"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67656.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          143 c          131 g           94 t
ORIGIN      
        1 acatgggctg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgaa ttgactcagt
      121 caccctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa aactgtgcac tggtaccaac agaagccacc gcagggccct gtattggtca
      241 tctttgctga tagtagacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001919             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:13387:19927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001919
VERSION     KCWK01001919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13387:19927"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67657.1"
                     /translation="DYYCHVYDSSRNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          165 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcgtcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agctgctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctcc gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtcgtaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001920             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:21991:18214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001920
VERSION     KCWK01001920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21991:18214"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67658.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          160 c          117 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgttgccta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggcgctgg agtccccagc cgcttctctg
      301 gatccaataa tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tccttacatc ttcggtgctg
      421 ggacccgtct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001921             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:10842:6941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001921
VERSION     KCWK01001921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10842:6941"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..406
                     /note="immunoglobulin light chain variable region"
     V_region        58..406
     V_segment       58..369
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67659.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       370..406
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           86 a          149 c          107 g          102 t
ORIGIN      
        1 acatgggtga ctcctctcct cctcctgctc ctctctcact gcacaggttc cctctcccag
       61 cctgtgctga ctcagccacc ctccctgtct gcatccccgg gagcatcggc cagactcccc
      121 tgcaccctga gcagtgacct cagtgttggt gttaaaaaca tgtactggta ccagcagaag
      181 ccagggagcg ctcccaggtc attcctatac tactactccg actcagacaa gcagctggga
      241 cctggggtcc ccaatcgagt ctctggctcc aaggagacct caagtaacac agcgtttttg
      301 ctcatctctg gactccagcc tgaggacgag gccgattatt actgtcaggt gtatgacagt
      361 agtgctaatg tgttattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct
      421 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001922             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:13253:13760
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001922
VERSION     KCWK01001922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13253:13760"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..395
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67660.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       398..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           82 a          155 c          127 g          106 t
ORIGIN      
        1 acatgggggg tggctcagga agcagagcct ggagcatctc caccatggcc tgggctccac
       61 tcctcctcac cctcctcgct cactgcacag ggtcttgggc tgaggttgtg ttcactcagc
      121 cccaatctgt gtcggggtct ccggggcaga cggtcaccat ctcctgcacc cgcagcagtg
      181 gcagcattgg caacagctat gtgtactggt tccagcagcg gccgggcagc gtccccacta
      241 ttgtgattta caaagatgac caaagaccct ctggggtccc tgatcggttc tctggctcca
      301 tcgacagctc ctccaactct gcctccctca ccatctctgg actgaagtct ggggacgagg
      361 ctgactatta ctgtcagtct tttgacagca gcagtgtctt attcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001923             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:21116:10419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001923
VERSION     KCWK01001923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:21116:10419"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67661.1"
                     /translation="DYYCSAWDSSLTGGLF"
     J_segment       410..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           97 a          157 c          124 g          107 t
ORIGIN      
        1 acatgggggc tcagcttcag ctgtggctag agaagacagg actcaggaca atctccagca
       61 tggcctgctt ccctctcatc ctcaccgtcc tcactcactg tgcaggatcc tgggcccagt
      121 ctgtgctgac tcaaccaccc tcagcgtctg gggcccccgg gcagagtgtc accatctcct
      181 gttctggaag cagctccaac atcggaagta attatgtata ctggtaccag cagttctcag
      241 ggaaggcccc caaactcctc atccataata ataatcagcg accctcaggg gtccctgatc
      301 gattctctgg ctccaagtct ggcacgtcag cctccctggc catcagtggg ctccagtccg
      361 aggatgaggc tgattattac tgctcagcat gggatagcag tctgaccggt ggcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01001924             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:14432:4881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001924
VERSION     KCWK01001924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14432:4881"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67662.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       390..424
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT          106 a          136 c          120 g          100 t
ORIGIN      
        1 acatggggtg gttctaggag gaagagctct gggtgtctca ccatgacctg gaccactgtt
       61 ctgctcccct ttctcactct ctgcacaggc tctgaggcct cctatgagct gacacagcca
      121 ccctcagtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agaaatactg
      181 gcaaaaaaat atactcagtg gttccagcag cagccaggcc aggccccttt cctggtgata
      241 tataaagaca gtgagaggcc ctcagggatc cctgagcgat tctctagctc cagttcaggg
      301 acaacaatta ccttgaccat cagtggggcc caggcagaag atgaggctga ctattactgt
      361 caatcagtag acagcagtgg aaatcttccg ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001925             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:14889:9570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001925
VERSION     KCWK01001925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:14889:9570"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67663.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           88 a          153 c          128 g          111 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg aggttattat gtgcagtggt accagcagct tccagggacg
      241 gcccccaaac tcctcatcta tgaaaatgat aaacgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctgattc ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagcttga gtgttgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001926             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:19167:9686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001926
VERSION     KCWK01001926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19167:9686"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67664.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       386..421
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           97 a          143 c          121 g           98 t
ORIGIN      
        1 acatgggggg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactcccca tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agaagaattg
      181 ccaaaaaaat atgcttattg gttccagcag aagccaggcc agtcccctgt ccagatcatc
      241 tatgaggaca gtaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cactggggcc caggtggagg atgaagctga ctactactgt
      361 ttctcaacag acaccagtgg taatcgggta ttcggcggag ggacccgtct aaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001927             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:3393:15266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001927
VERSION     KCWK01001927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:3393:15266"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..398
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67665.1"
                     /translation="DYYCSSYGGSNTLFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           89 a          152 c          121 g          109 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 actccctctg tgtccgggtc tcctggacag tcggtcacca tcacctgcac tggaaccagc
      181 agtgatattg ggtattatca tgctgtgtct tggtaccagc atcatccagg caaagccccc
      241 aaactcatga tttatgaggt caataaacgg cccgcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacgcggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 gattattact gcagctcata tggaggcagc aatactttat tcttcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01001928             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:25027:9533
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001928
VERSION     KCWK01001928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:25027:9533"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..404
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67666.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           95 a          157 c          119 g          109 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggtacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcagc ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct
      181 ggaagcacct ccaacatcgg aagcaataat gtatcctggt accagcagct cccaggaaca
      241 gctcccaaac tcctctttta ttataatgat caacgagcct caggtgtctc tgaccgattc
      301 tcttgctcca agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat
      361 gaggctgatt attactgcgc agcatgggat gataacctga gcggctacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01001929             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:17871:15374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001929
VERSION     KCWK01001929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17871:15374"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67667.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           81 a          148 c          139 g           96 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtccgtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttcgaaggga agttgtgaac tggtaccagc agaagccagc gcaggcccct gtcttggtca
      241 tctttgctga ttccgaacgg ccctcaggga tccccgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atccgcgggg tcgaggccgg ggatgaggct gacttttact
      361 gtcaggtgtg ggacattcgt agtgatcgtc cgctattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001930             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:13749:6955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001930
VERSION     KCWK01001930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13749:6955"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..388
                     /note="immunoglobulin light chain variable region"
     V_region        58..388
     V_segment       58..349
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <313..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67668.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       354..388
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           79 a          136 c          108 g          103 t
ORIGIN      
        1 acatgggggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
       61 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt cacgatctcc
      121 tgcagtggga gcaactccaa cattggatat tattatgtgc agtggtacca gcagcttcca
      181 ggaacggccc ccaaactcct catctatgaa aataataagc gaccctctgg ggtttctgat
      241 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      301 gaggatgagg ctgattatta ctgccactcc tatgacagca gtttgagtgg tgtcttattc
      361 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      421 ttcccg
//
LOCUS       KCWK01001931             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:8749:10590
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001931
VERSION     KCWK01001931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:8749:10590"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67669.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       415..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          164 c          120 g          113 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtggtaaaaa catttactgg taccagcaga agccagggcg cgctcccagg
      241 tttttcctgt actacaactc cgactcagac aagcagctgg gacctggggt ccccaatcgc
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcac gtatatgaca gtagtactaa tgttttattc
      421 ggaggaggga cccgtctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01001932             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:5018:13685
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001932
VERSION     KCWK01001932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:5018:13685"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67670.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       414..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           96 a          157 c          127 g          108 t
ORIGIN      
        1 acatggggga agcgcagctt cagctgtggg tacagaaggc aggactcagg acaatctcca
       61 gcatggcctg gttccctctc gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc
      121 agtctgtgct gactcagcct ccctcagcgt ctgaggccgc caggaacagt gtcgccatct
      181 cctgttctgg aagcagctcc aacatcggaa gtcatagtgt atcctggtac cagcagctcc
      241 caggaacagc tcccaaactc ctcatctatt atgatgatca acgagcctca agtgtctctg
      301 accgattctc tggctccagg tctggcacgt cagcctccct ggccatcagt gggctccaga
      361 ccgaggatga ggctgattat tactgcgcag catgggatga tagcctgaga ggttacatct
      421 tcggtgatgg gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCWK01001933             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:22593:10233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001933
VERSION     KCWK01001933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22593:10233"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..450
                     /note="immunoglobulin light chain variable region"
     V_region        114..450
     V_segment       114..407
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67671.1"
                     /translation="DYYVSAWDSSLSINYIF"
     J_segment       413..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           95 a          158 c          123 g          112 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaacatc ggggcgggtt attatgtatc ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaaa ataataaacg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattac gtctcagcat gggatagcag cctgagtatc aattacatct
      421 tcggttctgg gacccgtctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCWK01001934             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:8075:5999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001934
VERSION     KCWK01001934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8075:5999"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..380
                     /note="immunoglobulin light chain variable region"
     V_region        87..380
     V_segment       87..343
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>352
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67672.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       347..380
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        381..>418
                     /gene="IGLC"
BASE COUNT           82 a          123 c          127 g           86 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagt gtcccccgga cagacggcca ggatcacctg
      121 tgggggagac aacattggaa gtgaagttgt gaactggtac cagcagaagc caccgcaggc
      181 ccctgtgttg gtcatgtatg ctgatagcga gcggccctca gggatccctg agcgattctc
      241 tggctccaaa tcagggaaca cggccaccct gaccatcagc ggggtcgagg ccggggatga
      301 ggctgactat tactgtcagg tgtgggacat gaatagtcat catctattat tcggaggagg
      361 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001935             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:14187:13141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001935
VERSION     KCWK01001935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14187:13141"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67673.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       402..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          161 c          117 g          108 t
ORIGIN      
        1 acatgggggt ggcctcagag gtagccgtgt ccaccatggc cctgactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgactcag ccaccctccc
      121 tgtctgcatc cccgggagca tcggccagac tcccctgcac cctgagcagt gacctcagtg
      181 ttggtaataa aaacatgtac tggtaccaac agaagccagg gagcgctccc aggttattcc
      241 tgtactacta ctccgactca gacaagcagc tgggacctgg ggtccccaat cgagtctctg
      301 gctccaagga gacctcaact aacacagcgt ttttgctcat ctctgggctc cagcctgagg
      361 acgaggccga ttattactgt caggtgtttg acagtagtgc tgtgttattc ggaggaggga
      421 cccgactgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001936             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:4617:15526
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001936
VERSION     KCWK01001936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4617:15526"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67674.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          157 c          120 g          110 t
ORIGIN      
        1 acatggggga gcctcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcctcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgttgactca gcctccctca gcgtctgagg ccgccgggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata gtgtatcctg gtaccaacaa ctcccagaaa
      241 cggctcccaa actcctcatg tattataatc atcggcgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acttcagcct ccctggccat cagtggcctc cagaccgagg
      361 atgaggctga ttattactgc gcagtatggg atgatagcct gaccggttac atcttcggta
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01001937             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:9031:14783
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001937
VERSION     KCWK01001937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9031:14783"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67675.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          157 c          124 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggcggttata actatgtctc ctggtaccaa caacatccag acacagcccc
      241 caaactcatg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctcctggctg aggacgaggc
      361 tgattattac tgctgctcac atgcaggcag tgatattttc gtattattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001938             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:21865:3392
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001938
VERSION     KCWK01001938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21865:3392"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67676.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          159 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc ccaaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacga tagtgctgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001939             295 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:12151:15648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001939
VERSION     KCWK01001939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 295)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12151:15648"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..257
                     /note="immunoglobulin light chain variable region"
     V_region        5..257
     V_segment       5..221
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <185..>229
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67677.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       225..257
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>295
                     /gene="IGLC"
BASE COUNT           66 a           85 c           84 g           60 t
ORIGIN      
        1 acatggggac aacattggaa ctaaaactgt gcactggtac cagcagaagc caccgcaggg
       61 ccctgtattg gtcatctttg ctgatagtaa acggccctca gggatccctg agcgattctc
      121 tggctccaac tcagggaaca ccgccaccct gaccatcagc agggtcgagg ccggggatga
      181 ggctgactat tactgtcagg tttgggacag tagtagtaaa tggatattcg gcggggggac
      241 ccggctaacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001940             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:11486:19525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001940
VERSION     KCWK01001940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11486:19525"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..418
                     /note="immunoglobulin light chain variable region"
     V_region        101..418
     V_segment       101..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67678.1"
                     /translation="DYYCYSPDNNSKWIF"
     J_segment       390..418
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>460
                     /gene="IGLC"
BASE COUNT          100 a          141 c          123 g           96 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatagcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgaga tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttcccgca gaaggcaggc cagcccccta tggtgatcat
      241 ctatgaggac accaaacggc cctctgggat cccggagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttactcacca gacaacaata gtaaatggat attcgacgga gggacccggc tgaccgtcgt
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01001941             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:16782:6220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001941
VERSION     KCWK01001941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16782:6220"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..394
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67679.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       408..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           88 a          157 c          121 g          110 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccccga
      121 ctcagactcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tattgggtat tatcatgctg tgtcttggta ccagcatcat ccaggcaaag
      241 cccccaaact catgatttat gaggtcaata aacggcccgc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag actgaggatg
      361 agcctgatta ttactgcagc tcatatgcag gcagcaacgc tttattcttc ggaggaggga
      421 cccgcctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001942             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:4519:6459
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001942
VERSION     KCWK01001942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4519:6459"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67680.1"
                     /translation="DYYCQVWDSSSYHRVF"
     J_segment       392..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          152 c          131 g           91 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gcctctgcga cctcctatgg actgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acgaccacga tcacctgtgg gggagacaac
      181 attggaagta aatatgtaca ttggtaccag cagaagccaa cacaggcccc tgtgcaggtc
      241 atctatgctg ataccagacg gccctcaggg atccctgacc gcttctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagttatcat cgggtcttcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001943             285 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:15236:12266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001943
VERSION     KCWK01001943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 285)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15236:12266"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..247
                     /note="immunoglobulin light chain variable region"
     V_region        9..247
     V_segment       9..210
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <172..>219
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67681.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       213..247
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        248..>285
                     /gene="IGLC"
BASE COUNT           55 a           87 c           84 g           59 t
ORIGIN      
        1 acatgggcta aatatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
       61 atctatgctg ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      121 gggaacaccg ccaccctgac catcagcggg gtcgaggccg ggtatgaggc tgactatttc
      181 tgtcaggtgt gggacgatag tagtgatcat ccggtattcg gcggagggac ccggctgacc
      241 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001944             490 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:17820:9511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001944
VERSION     KCWK01001944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 490)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17820:9511"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..452
                     /note="immunoglobulin light chain variable region"
     V_region        122..452
     V_segment       122..415
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>424
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67682.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       416..452
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>490
                     /gene="IGLC"
BASE COUNT           92 a          158 c          124 g          116 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcacttc acagttccag ggtcctgggc
      121 ccagtctgtg ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat
      181 ctcctgcact gggagcagct ccaacattgg agattatttt gtgcagtggt accagcacct
      241 tccaggaacg gcccccaaac tcctcatcta tgaaaataat aagcgaccct cagggatttc
      301 tgatcgattc tctggctccc agtctggaac ctcagcctcc ctgaccatca ctggactcca
      361 gtctgaggat gaggctgatt attactgcca gtcctatgac agcagtttga ttgctgtgtt
      421 attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac
      481 tctcttcccg
//
LOCUS       KCWK01001945             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:4286:11919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001945
VERSION     KCWK01001945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4286:11919"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..391
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67683.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          144 c          133 g           95 t
ORIGIN      
        1 acatgggggg tctgggtctc aggaggcagc attgacggtg cctcagccat ggcctggacc
       61 cttctcctcc tcggcctcct cgcttactgc acaggctctg cgacctccta tgaattgact
      121 cagtcaccct cagtgtcagc ggcctcagga cagccggcca ggatcacctg tgggggagac
      181 aacattggaa ctaaaactgt gcactggtac caacagaagc caccgcaggg ccctctattg
      241 gtcatctttg ctgatagtag acggccctca gggatccctg agcgattctc tggctccaac
      301 tcagggaaca ccgccaccct gaccatcagc agggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtagtaaa tggatattcg gcggggggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001946             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:17184:9182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001946
VERSION     KCWK01001946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17184:9182"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..444
                     /note="immunoglobulin light chain variable region"
     V_region        96..444
     V_segment       96..405
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67684.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       407..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           97 a          155 c          113 g          117 t
ORIGIN      
        1 acatggggcc cactgcaggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcgcagcc tgtgctgact cagccaacct
      121 ccctctcagc atctcctgga gcatcagcca gactcacctg caccttgaac agtggcatca
      181 gtgttggtaa ttacaggata ttctggtacc accagaagcc agggagtcct ccccggtatc
      241 ttctgaacta ccacacagac tcagatattc atcaggggtc tggagtcccc agccgcttct
      301 ctggatccaa agatgcttcg gccaatgcag ggattttact catctctgga ctccagtctg
      361 aggatgaggc tgactattac tgtatgattt ggcacaacaa tgcttattgg gttttcggcg
      421 gagggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001947             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:10638:4537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001947
VERSION     KCWK01001947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:10638:4537"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..407
                     /note="immunoglobulin light chain variable region"
     V_region        87..407
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67685.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       372..407
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>446
                     /gene="IGLC"
BASE COUNT           93 a          141 c          115 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aagatcacct gctctggaga tgcactgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcgat gaggacacca
      241 aacgaccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gcagtggtta tggcttattc ggaggaggga cccggctgac cgtcctacgt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001948             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:15894:12341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001948
VERSION     KCWK01001948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15894:12341"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..455
                     /note="immunoglobulin light chain variable region"
     V_region        125..455
     V_segment       125..418
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67686.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       419..455
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           97 a          157 c          129 g          110 t
ORIGIN      
        1 acatggggtg ggtgaagcgc agcttcagct gtgggtacag aaggcaggac tcaggacaat
       61 ctccagcatg gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg
      121 ggcccagtct gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac
      181 catctcctgt tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca
      241 cctcccagga acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt
      301 ctctgaccga ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct
      361 ccagaccgag gatgaggctg attattactg cgcagcgtgg gatgataggc tgagcagtta
      421 catcttcgct gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt
      481 cactctgttc ccg
//
LOCUS       KCWK01001949             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:8419:3848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001949
VERSION     KCWK01001949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8419:3848"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    29..275
                     /note="immunoglobulin light chain variable region"
     V_region        29..275
     V_segment       29..238
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <200..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67687.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       239..275
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>313
                     /gene="IGLC"
BASE COUNT           67 a           93 c           83 g           70 t
ORIGIN      
        1 acatgggaat caacgcagag tacatgggat cggaagtcat agtgtatcct ggtaccagca
       61 gctcccagga acagctccca aactcctcat ctattatgat gatcaacgag cctcgggtgt
      121 ctctgaccga ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct
      181 ccagaccgag gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta
      241 catcttcggt gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt
      301 cactctgttc ccg
//
LOCUS       KCWK01001950             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:13651:3632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001950
VERSION     KCWK01001950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13651:3632"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67688.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           91 a          153 c          120 g          109 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctactgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgactatta ctgcagctca tatgcaggca gcaacagttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001951             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:6321:15920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001951
VERSION     KCWK01001951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6321:15920"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..282
                     /note="immunoglobulin light chain variable region"
     V_region        8..282
     V_segment       8..245
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67689.1"
                     /translation="DYYCQVWDISSDHVLF"
     J_segment       246..282
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>320
                     /gene="IGLC"
BASE COUNT           67 a           87 c          101 g           65 t
ORIGIN      
        1 acatgggggc caggatcacc tgtgggggag acaacattgg aagtgaactt gtgaactggt
       61 accaacagag gccaccgcag gcccctgtgc tggtcatgta tgctgatagc gaacggccct
      121 cagggatccc tgagcgattc tctggctcca aatcagggaa tacggccacc ctgaccatca
      181 gcggggtcga ggccggggat gaggctgact attactgtca ggtgtgggac attagtagtg
      241 atcatgtgtt attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      301 cctcggtcac tctcttcccg
//
LOCUS       KCWK01001952             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:14101:10381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001952
VERSION     KCWK01001952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14101:10381"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67690.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          157 c          121 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc aacgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca actccaacat cggaagttat aatgtgtcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01001953             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:16249:15447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001953
VERSION     KCWK01001953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16249:15447"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67691.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       398..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           87 a          156 c          122 g          104 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcatctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagcattgac aacggctttg tgtactggta ccagcagcgg ccgggcagcg ctcccaccac
      241 tgtgatttac aaagataacc aaagaccctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctgga ctgaaatctg aggacgaggc
      361 tgactattac tgtcagtctt atgacagcag cagtgtatta ttcggaggag ggacccgact
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001954             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:17115:13200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001954
VERSION     KCWK01001954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17115:13200"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..336
                     /note="immunoglobulin light chain variable region"
     V_region        12..336
     V_segment       12..299
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <261..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67692.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       302..336
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           76 a          108 c          112 g           78 t
ORIGIN      
        1 acatgggggc ctcctatgag ttgcctcagc cacgctcagt gtccgtgtcc ccaggacaga
       61 cggccaggat cacctgtggg ggagacaaca ttggaagtaa tagtgtgcat tggtaccagc
      121 agaagccacc gcgggcccct gtattggtca tctctgttga tagcgaacgg ccctcaggga
      181 tccctgagcg attctctggt tccagatcag ggaacaccgc caccctgacc atcagcgggg
      241 tcgaggccgg ggatgaggct gactattact gtcaggtgtg ggataatatt tataaatacg
      301 cggtattcgg cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      361 tcactctctt cccg
//
LOCUS       KCWK01001955             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:24849:16064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001955
VERSION     KCWK01001955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24849:16064"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..336
                     /note="immunoglobulin light chain variable region"
     V_region        12..336
     V_segment       12..298
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <261..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67693.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       300..336
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           80 a          115 c          104 g           75 t
ORIGIN      
        1 acatgggggc ctcctatgat ctgactcagc caccctcggt gtcagtgtcc ccaggacaga
       61 cggccaggat cacctgtggg ggagacaaca ttggaagtca aagtgtgcac tggtaccagc
      121 acaagccacc gcaggcccct gtactggtca tcttttatta taccgaacgg ccctcaggaa
      181 tccctgagcg attctctggc tccaaatcag ggaataccgc caccctgacc atcagcgggg
      241 tcgaggccgg ggatgaggct gactattact gtcaggtgtg ggacacaact attgatcacg
      301 gcttattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      361 tcactctctt cccg
//
LOCUS       KCWK01001956             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:5836:14321
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001956
VERSION     KCWK01001956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:5836:14321"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67694.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           84 a          157 c          127 g          107 t
ORIGIN      
        1 acatgggggg ggtctcggga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggcggttata actatgtctc ctggtaccga caacatccag acacagcccc
      241 caaactcatg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctgctcac atgcaggcag tgatattttc gtgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001957             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:7973:10266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001957
VERSION     KCWK01001957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7973:10266"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67695.1"
                     /translation="DYHCQVFDSSDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          162 c          123 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtttgacag tagtgatgtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001958             455 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:20064:5619
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001958
VERSION     KCWK01001958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 455)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20064:5619"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..417
                     /note="immunoglobulin light chain variable region"
     V_region        87..417
     V_segment       87..378
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <345..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67696.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       387..417
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>455
                     /gene="IGLC"
BASE COUNT           88 a          148 c          114 g          105 t
ORIGIN      
        1 acatgggggc agcactcagg acagtctcca gcatggcctg gtctctcctt ctcactctgc
       61 tggttcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc tcagtatctg
      121 gggcccccgg acagagggtc accatctcct gcattagcag cagctccaac atcggggcgg
      181 cttattatgt atcctggtac caacagttcc caggaacagc ccccaaactc ctcatctttg
      241 aaaataataa gcgaccctca ggggtttctg accgattctc tggctccaag tctggtccct
      301 cagcctccct gaccatcact ggactccaat ctgaggatga gggtgattat tactgtttag
      361 catgggatac cagcctgaat tggatcttcg gcggagggac ccggctgacc gtcctaggtc
      421 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001959             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:8088:6771
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001959
VERSION     KCWK01001959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8088:6771"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67697.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       387..424
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           89 a          136 c          140 g           97 t
ORIGIN      
        1 acatggggga ctttgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctttacaggc tctgcggcct cctatgaggt gactcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtaaaa gtgtgcagtg gtaccagcag acgccaccgc aggcccctgt actggtcatt
      241 tatggtgata gggaacggcc ctcagggatc cctgagcgat tctctggttc caactcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg atagtagtag taaatatgtg ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001960             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18082:17435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001960
VERSION     KCWK01001960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18082:17435"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..444
                     /note="immunoglobulin light chain variable region"
     V_region        96..444
     V_segment       96..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67698.1"
                     /translation="DYYCGLGHSSGDYIF"
     J_segment       407..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           96 a          161 c          117 g          108 t
ORIGIN      
        1 acatggggcc cactgtgggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctccaagcc tatgctgact cagccggcct
      121 ccctctcagc atctcctgga gcatcagcca gtctcacatg caccttcacg ggtggcatca
      181 atgttgctga ctaccacata cactggtacc agcagaagcc agggagtccc ccccggtatc
      241 ttctgaggta caaatcagac tcagataagg gccagggctc tggagtcccc agccgcttct
      301 ctggatccaa agatgcttca gcgaacacag ggattttaca catctctgga ctccagtctg
      361 aggatgaggc tgactattac tgtggccttg ggcacagcag cggtgattac atcttcgctg
      421 atgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01001961             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:14104:17692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001961
VERSION     KCWK01001961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14104:17692"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67699.1"
                     /translation="YYYCSSYAGSHTYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           81 a          165 c          118 g          111 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacagggtcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtgctt ataactatgt ctcctggttc cagcagcacc caggcaaagc
      241 ccccaaactc atgatttatg atgtcactca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctggctaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggcttattat tactgcagct catatgcagg cagccacact tacatcttcg gtcctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001962             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:20404:13282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001962
VERSION     KCWK01001962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20404:13282"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67700.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          163 c          120 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acccggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001963             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:14317:14931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001963
VERSION     KCWK01001963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14317:14931"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..424
                     /note="immunoglobulin light chain variable region"
     V_region        101..424
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67701.1"
                     /translation="DYYCQVWDTSFDHGLF"
     J_segment       389..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>463
                     /gene="IGLC"
BASE COUNT           91 a          145 c          129 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtt ttgatcacgg cttatttgga ggagggaccc ggctgaccgt
      421 cctaagtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001964             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:19412:17141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001964
VERSION     KCWK01001964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19412:17141"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..387
                     /note="immunoglobulin light chain variable region"
     V_region        97..387
     V_segment       97..352
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <315..>359
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67702.1"
                     /translation="DYYCSSYGGRNTLFF"
     J_segment       357..387
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        388..>425
                     /gene="IGLC"
BASE COUNT           86 a          134 c          107 g           98 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg acagtcggtc accatctcct
      121 gcactggaac cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc
      181 caggcaaagc ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg
      241 atcgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga
      301 ctgaggatga ggctgattat tactgcagct catatggagg cagaaacact ttattcttcg
      361 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg ctcactctct
      421 tcccg
//
LOCUS       KCWK01001965             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14150:12804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001965
VERSION     KCWK01001965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14150:12804"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67703.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          161 c          120 g          108 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcgtcaatg
      181 tgggtagtta cagcgtattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacca gtcagactca aggaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc tgttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccctatggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001966             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:7496:8774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001966
VERSION     KCWK01001966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:7496:8774"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..336
                     /note="immunoglobulin light chain variable region"
     V_region        8..336
     V_segment       8..292
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67704.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       306..336
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           74 a          116 c           95 g           89 t
ORIGIN      
        1 acatgggggc tgccccgact cagactccct ctgtgtccgg gtctcctgga cagtcggtca
       61 ccatctcctg cactggaacc agcagtgata ttgggtatta tcatgctgtg tcttggtacc
      121 agcatcatcc aggcaaagcc cccaaactca tgatttatga ggtcaataaa cggcccgcag
      181 gggtctctga tcgcttctct ggctccaagt ctggcaacac ggcctccctg accatctctg
      241 ggctccagac tgaggatgag gctgattatt actgtagctc atatgcaggc agcaacagtt
      301 tattcttcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      361 tcactctctt cccg
//
LOCUS       KCWK01001967             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:22201:8380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001967
VERSION     KCWK01001967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:22201:8380"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67705.1"
                     /translation="DYYCQVWDISSDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           87 a          143 c          135 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagc ctctgcggcc tcctatgctc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacct
      181 tggatatgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgtggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacattagta gtgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001968             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:13942:16770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001968
VERSION     KCWK01001968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13942:16770"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67706.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       392..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          140 c          141 g           96 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgc ggcctcctat gaggtgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taaaagtgtg cagtggtacc agcagacgcc accgcaggcc cctgtactgg
      241 tcatttatgg tgatagggaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggatagc agtagtaaat atgtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001969             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:14860:15477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001969
VERSION     KCWK01001969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14860:15477"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67707.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          162 c          111 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcatgttc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctggtctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001970             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:19013:13473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001970
VERSION     KCWK01001970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19013:13473"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..398
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67708.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       400..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           95 a          154 c          110 g          116 t
ORIGIN      
        1 acatggggca gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctcgca gcctgtgctg actcagccaa cctccctctc
      121 agcttctcct ggagcatcag ccagactcac ctgcaccttg aacagtggca tcagtgttgc
      181 taattacagg atattctggt accaccagaa gccagggagt cctccccggt atcttctgaa
      241 ctaccacaca gactcagata ttcaccaggg ctctggagtc cccagccgct tctctggatc
      301 caaagatgct tcggccaatg cagggatttt actcatctct ggactccagt ctgaggatga
      361 ggctgactat tactgtatga tttggcacaa caatgcttat tgggttttcg gcggagggac
      421 ccggctaacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001971             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:5621:16947
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001971
VERSION     KCWK01001971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5621:16947"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67709.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggctgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001972             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:11451:8218
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001972
VERSION     KCWK01001972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11451:8218"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..441
                     /note="immunoglobulin light chain variable region"
     V_region        111..441
     V_segment       111..404
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67710.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          154 c          126 g          105 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actgtgcagg gtcctgggcc cagtctgtgc
      121 tgactcagac tccctcagcg tctgaggccg ccaggaagag tgtcaccatc tcctgttctg
      181 gaagcagctc caacatcgga agaaatagtg tatcctggta ccagcagctc ccaggaacag
      241 ctcccaaact cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct
      301 ctggctccaa gtctggcacg tcagcctccc tggccatcag cgggctccag gccgaggatg
      361 aggctgatta ttactgcgca gcatgggatg atagcctgag cggttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001973             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:14684:11301
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001973
VERSION     KCWK01001973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14684:11301"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67711.1"
                     /translation="DYYCSIGHSSGLYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          157 c          117 g          114 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtttcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgagggtga ctattactgt tccattggac acagcagcgg tctttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01001974             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:11781:6670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001974
VERSION     KCWK01001974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11781:6670"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67712.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          153 c          121 g          111 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat tatgctgtgt cttggtacca gcatcatcca ggcaaagccc
      241 ccaagctcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01001975             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:16205:5127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001975
VERSION     KCWK01001975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16205:5127"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67713.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          152 c          116 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccgg gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta atagtgtatc ctggtaccaa caactcccag aaacggctcc caaactcctc
      241 atgtattata atcatcggcg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacttcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagtat gggatgatag cctgaccggt tacatcttcg gtggtgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001976             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:21565:17157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001976
VERSION     KCWK01001976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:21565:17157"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67714.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          162 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgtaccctg agcagtgccc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001977             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:5773:17937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001977
VERSION     KCWK01001977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:5773:17937"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..424
                     /note="immunoglobulin light chain variable region"
     V_region        79..424
     V_segment       79..387
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67715.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       390..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           83 a          159 c          114 g          106 t
ORIGIN      
        1 acatggggag ccgtgtccac catggccctg actcctctcc tcctcctgct cctctctcac
       61 tgcacaggtt ccctctccca gcctgtgctg actcagccac cctccctgtc tgcatccccg
      121 ggagcatcgg ccagactccc ctgcaccctg agcagtgacc tcagtgttgg tagtaaaaac
      181 atgtactggt accagcagaa gccagggagc gctcccaggt tattcctgta cttctactcc
      241 gactcagaca agcagctggg acctggggtc cccgatcgcg tctctggctc caaggagacc
      301 tcaagtaaca cagcgttttt gctcatctct gggctccagc ctgaggacga ggccgattat
      361 tactgtcagg tgtttgacag tagtgctgtc ttattcggag gagggacccg actgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01001978             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:5370:14458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001978
VERSION     KCWK01001978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5370:14458"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..446
                     /note="immunoglobulin light chain variable region"
     V_region        110..446
     V_segment       110..403
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67716.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       409..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           95 a          156 c          123 g          110 t
ORIGIN      
        1 acatgggggg cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctctc cttctcactc tgctggttca ctgcacaggg tcctgggccc agtctgtgct
      121 gacgcagccg ccctcagcat ctggggcccc cgggcagagg gtcaccatct cctgcactgg
      181 gagcagctcc aacatcgggg cgggttatta tgtatcctgg taccagcagt tcccaggaac
      241 agcccccaaa ctcctcatct atgaaaataa taaacgaccc tcaggggttt ctgaccgatt
      301 ctctggctcc aagtctggta cctcagcctc cctgaccatc actggactcc aatctgagga
      361 tgaggctgat tattactgct cagcatggga tagcagcctg agtatcaatt acatcttcgg
      421 ttctgggacc cgtctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01001979             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:17757:13771
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001979
VERSION     KCWK01001979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17757:13771"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..387
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67717.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       393..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          152 c          116 g          106 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gcatctgggg cccccgggca gagggtcacc atctcctgca ctgggagcag ctccaacatc
      181 ggggcgggtt attatgtatc ctggtaccag cagttcccag gaacagcccc caaactcctc
      241 atctatgaaa ataataaacg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggtacctcag cctccctgac catcactgga ctccaatctg aggatgaggc tgattattac
      361 tgctcagcat gggatagcag cctgagtatc aattacatct tcggttctgg gacccgtctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01001980             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:21163:2975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001980
VERSION     KCWK01001980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21163:2975"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..313
                     /note="immunoglobulin light chain variable region"
     V_region        7..313
     V_segment       7..276
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <241..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67718.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       277..313
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>351
                     /gene="IGLC"
BASE COUNT           79 a          109 c           84 g           79 t
ORIGIN      
        1 acatggggag catcagccag tctcacatgc accttcagcg gtggcatcaa tgttgttgcc
       61 taccacatac actggtacca gcagaagcca gggagtcccc cccggtatct tctgagttac
      121 aaatcagact cagataaggg ccagggctct ggagtcccca gccgcttctc tggatccaaa
      181 aatggttcaa caaacacagg cattttacac atctctgggc tccagtctga ggatgaggct
      241 gactatttct gtgccattgg acacagcagc ggtccttaca tcttcggtac tgggacccgg
      301 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01001981             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16061:8733
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001981
VERSION     KCWK01001981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16061:8733"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..388
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67719.1"
                     /translation="DYYCGAWDSSLSGYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          153 c          117 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg acttgggaca atcttcatca tgacctggtc ccctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtcctgac gcagccgccc
      121 tcagtgtctg cggccccagg gcagaaggtc accatctcct gctctggaag tagctccaac
      181 atcgggagaa attctgtctc ctggtaccag caggtcccag gaacggcccc caaactcctc
      241 acctatgaca atgataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggttcctcag cctccctggc catcactgga ctccagactg gagatgaggc tgattattac
      361 tgcggagcat gggatagcag tctgagtggt tacattttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001982             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:26660:6723
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001982
VERSION     KCWK01001982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:26660:6723"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67720.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          150 c          117 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacgctg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001983             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:22570:10013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001983
VERSION     KCWK01001983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22570:10013"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67721.1"
                     /translation="DYYCATWDDSLSGPVF"
     J_segment       411..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          155 c          129 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccggcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtatcct ggtaccagca gttcccagaa
      241 acggctccca aattcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcaacatgg gatgatagcc tgagcggtcc ggtattcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001984             361 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:9915:23158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001984
VERSION     KCWK01001984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 361)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9915:23158"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..323
                     /note="immunoglobulin light chain variable region"
     V_region        8..323
     V_segment       8..286
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <251..>295
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67722.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       287..323
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        324..>361
                     /gene="IGLC"
BASE COUNT           79 a          116 c           86 g           80 t
ORIGIN      
        1 acatggggca actcctggag catcagccag tctcacatgc accttcagcg gtggcatcaa
       61 tgttgctgcc taccacatac actggtacca gcagaagcca gggagtcccc cccggtatct
      121 tctgacttac aaatcagact cagataaggg ccagggctct ggagtcccca gccgcttctc
      181 tggatccaaa aatgcttcaa cgaacacagg cattttacac atctctgggc tccagtctga
      241 ggatgaggct gactatttct gtgccattgg acacagcagc ggtccttaca tcttcggtgc
      301 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      361 g
//
LOCUS       KCWK01001985             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:10059:15883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001985
VERSION     KCWK01001985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10059:15883"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-38"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67723.1"
                     /translation="DYYCYSGDDYNLGVF"
     J_segment       396..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          141 c          132 g          103 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgaacg tctcaccatg gcctggatcc
       61 ctctcctgct ccccctcctc gccctctgca cagtctctgt ggcctcctgt gagctgacac
      121 agccaccctc ggtgtcgttg tcccttggac agacggccaa gattacctgc tctggagatg
      181 tactggcaaa agactttgct cattggtatc aacagaagcc aggccaggcg cctgtaatgg
      241 tgatttataa agacgttgag aggccctcag ggatccctga gcgattctct ggctccagct
      301 cagggaccac agtcaccctg agcatcagcg gggcccaggc tgaggatgag gctgactatt
      361 actgttactc tggggatgac tataatctag gagtgttcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01001986             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:5558:19973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001986
VERSION     KCWK01001986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:5558:19973"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67724.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       414..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          164 c          123 g          109 t
ORIGIN      
        1 acatggggtg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcct
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcactgac
      181 ctcagtgttg gtggtaaaaa catgtactgg taccagcaga agccaggaag cgctcccagg
      241 ttattgctgt attaccactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgccaa cacgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01001987             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:13283:7050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001987
VERSION     KCWK01001987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13283:7050"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..429
                     /note="immunoglobulin light chain variable region"
     V_region        81..429
     V_segment       81..390
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67725.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       395..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          158 c          109 g          114 t
ORIGIN      
        1 acatggggga ggctgtgtcc accatggcct ggactcctct cctcctcctg ctcctctctc
       61 actgcacagg ttccctttcc cagcctgtgc tgacccagcc aacctccctc tcagcatctc
      121 cgggagcatc agtccgactc agctgcacct tgagcagtgg catcaatgtt ggttcttaca
      181 ccatattctg gtaccagcag aagccaggga gtcctccccg gttccttctg tactactact
      241 cagactcaaa taatcaccag ggctctggag tccccagccg cttctctgga tccaaagatg
      301 cttcagccaa tgcagggctt ttactgatct ctgggctcca gtctgaagat gaggctgact
      361 attactgtgc catgtggcac agcagcgctt atgccttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01001988             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:8693:21466
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001988
VERSION     KCWK01001988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8693:21466"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67726.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       398..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           86 a          156 c          122 g          105 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcatctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagcattgac aacggctttg tgtactggta ccagcagcgg ccgggcagcg ctcccaccac
      241 tgtgatttac aaagataacc aaagaccctc tggggtccct gatcggttct cttgctccat
      301 cgacagctcc tccaactctg cctccctcac catctctgga ctgaaatctg aggacgaggc
      361 tgactattac tgtcagtctt atgacagcag cagtgtatta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001989             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:24597:21217
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001989
VERSION     KCWK01001989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24597:21217"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67727.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          155 c          115 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccgg cacctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgataa cctgagcggt tacatcttcg gttctgggac ccgactcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01001990             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:20513:5952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001990
VERSION     KCWK01001990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20513:5952"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..448
                     /note="immunoglobulin light chain variable region"
     V_region        121..448
     V_segment       121..408
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67728.1"
                     /translation="DYYCQVWDIYFDHPVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          149 c          143 g          104 t
ORIGIN      
        1 acatgggggg gaggaacctg cccagcctgg gcctcaggag gcagcattga cggtgcctca
       61 gccatggcct ggacttttct cctcctcggc ctccttgctt actgcacagg ctctgcggcc
      121 tcctatgatc tgactcagcc accctcggtg tcagtgtccc caggacagac ggccaggatc
      181 acctgtggag gagacaacat tggaagtgaa gttgtcaact ggtaccagca gaggccaccg
      241 caggcccctg tgctggtcat ctatgctgat tgtgaacggc cctcaggggt ccctgagcga
      301 ttctctggct ccaaatcagg gaacacggcc accctgacca tcagcggagt cgagcccggg
      361 gatgaggctg actattattg tcaggtgtgg gacatttatt ttgaccatcc ggtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01001991             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:20303:15605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001991
VERSION     KCWK01001991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20303:15605"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67729.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           86 a          163 c          122 g          112 t
ORIGIN      
        1 acatggggtg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aaccagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta tttctgccag gtgtttgaca gtagtgttgt gttcttcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01001992             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:6637:17694
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001992
VERSION     KCWK01001992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:6637:17694"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..450
                     /note="immunoglobulin light chain variable region"
     V_region        105..450
     V_segment       105..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67730.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       413..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           88 a          164 c          123 g          113 t
ORIGIN      
        1 acatggggaa ccctgggtct gtggcctcag aggtagccgt gtccaccatg gccctgactc
       61 ctctcctcct cctgctcctc tctcactgca caggttccct ctcccagcct gtgctgactc
      121 agccaccctc cctgtctgca tccccgggag catcggccag actcccctgc accctgagca
      181 gtgacctcag tgttggtagt aaaaacatgt actggtacca gcagaagcca gggagcgctc
      241 ccaggttatt cctgtactac tactccgact cagacaagca gctgggacct ggggtcccca
      301 atcgagtctc tggttccaag gagacctcaa gtaacacagc gtttttgctc atctctgggc
      361 tccagcctga ggacgaggcc gattatttct gccaggtgtt tgacagtagt gttgtgttct
      421 tcggaggagg gacccgactg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01001993             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:14141:20624
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001993
VERSION     KCWK01001993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14141:20624"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67731.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          138 c          135 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatt acctgtggag gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg aaggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01001994             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16675:18657
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001994
VERSION     KCWK01001994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16675:18657"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..398
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67732.1"
                     /translation="DYYCSAWDSSLTGGLF"
     J_segment       400..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           95 a          153 c          123 g          104 t
ORIGIN      
        1 acatggggag ctgtggctag agaagacagg actcaggaca atctccagca tggcctgctt
       61 ccctctcatc ctcaccgtcc tcactcactg tgcaggatcc tgggcccagt ctgtgctgac
      121 tcaaccaccc tcagcgtctg gggcccccgg gcagagtgtc accatctcct gttctggaag
      181 cagctccaac atcggaagta attatgtata ctggtaccag cagttctcag ggaaggcccc
      241 caaactcctc atccataata ataatcagcg accctcaggg gtccctgatc gattctctgg
      301 ctccaagtct ggcacgtcag cctccctggc catcagtggg ctccagtccg aggatgaggc
      361 tgattattac tgctcagcgt gggatagcag tctgaccggt ggcttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01001995             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:20738:5060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001995
VERSION     KCWK01001995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20738:5060"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..420
                     /note="immunoglobulin light chain variable region"
     V_region        100..420
     V_segment       100..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67733.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       385..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>459
                     /gene="IGLC"
BASE COUNT           94 a          143 c          123 g           99 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactcccca tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaagatca cctgctctgg agatgcactg
      181 ccaaaaaaat atgcttattg gttccagcag aagccaggcc agtcccctgt gttgatcatc
      241 gatgaggaca ccaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtggagg atgaagctga ctactactgt
      361 tactcagcag acagcagtgg ttatggctta ttcggaggag ggacccggct gaccgtccta
      421 cgtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01001996             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15348:9840
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001996
VERSION     KCWK01001996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15348:9840"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67734.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          159 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaattttgg aaataaaaac atatactggt accagcagag gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagttggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacga tagtgctgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001997             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:22590:17279
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001997
VERSION     KCWK01001997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22590:17279"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67735.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           82 a          162 c          122 g          102 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtggccac
      181 tacagctaca ccatcgcatg gcatcagcag cagcaaggga aggcccctcg gttcttgatg
      241 tggcttaaga gtgatggcag ccacaccaag ggggacgggg tccctgatcg cttctcaggc
      301 tccagctccg gggctgagtg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatattggc atttgggtat tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01001998             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:17723:5121
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001998
VERSION     KCWK01001998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17723:5121"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67736.1"
                     /translation="DYYCSSLESSLNWVF"
     J_segment       407..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          153 c          128 g          114 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgct
      181 ctgggagcag ctccaacatc ggggcgggtt tttatgtttc ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctttgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattat tgttcatcat tggaaagcag cctgaattgg gtattcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01001999             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:18014:5425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01001999
VERSION     KCWK01001999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18014:5425"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67737.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       402..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           85 a          159 c          124 g          108 t
ORIGIN      
        1 acatggggtg gggtctcagg aggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggcggttat aactatgtct cctggtacca acaccatcca gacacagccc
      241 ccaaactcat gatttatgag gtcactaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgctgctca catgcaggca gtgatatttt cgtgttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002000             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:9261:6473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002000
VERSION     KCWK01002000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9261:6473"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67738.1"
                     /translation="DYYCSSWASSLNWVF"
     J_segment       408..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           86 a          155 c          128 g          114 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg gttcactgca cagggtcctg ggcccagtct
      121 gttctgacgc agccgccctc agcatctggg gcccccgggc agagggtcac catctcctgc
      181 actgggagca gctccaacat cggggcgggt ttttctgttt cctggtacca gcagttcccg
      241 ggaacagccc ccaaactcct catctttgaa aataataacc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggttcctca gcctccctga ccatcactgg actccaatct
      361 gaggatgagg ctgattatta ttgttcatca tgggcaagca gcctgaattg ggtatttggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002001             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:21056:5718
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002001
VERSION     KCWK01002001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21056:5718"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..435
                     /note="immunoglobulin light chain variable region"
     V_region        92..435
     V_segment       92..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67739.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          161 c          112 g          112 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc tgcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatcg gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttcct
      241 tctactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt gctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002002             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:18709:5084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002002
VERSION     KCWK01002002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:18709:5084"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67740.1"
                     /translation="DYYCQSADSDGNHPLF"
     J_segment       398..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          105 a          136 c          124 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac agtctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc agtggttcca gcagaagcca ggccaggccc ctgtgttggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 aggaacaaca gttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagcg atggtaatca tccgttgttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002003             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:24421:16738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002003
VERSION     KCWK01002003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24421:16738"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..423
                     /note="immunoglobulin light chain variable region"
     V_region        93..423
     V_segment       93..384
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67741.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       386..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           85 a          148 c          121 g          107 t
ORIGIN      
        1 acatggggga ggcagcactc aggacagtct ccagcatggc ctggtctcct ctcctcctca
       61 cccttctcat tcactgcaca gggtcctggg cccagtctgt gctgacgcag ccgccctcag
      121 tgtctggggc gcccgggcag agggtcacca tctcctgcac tgggagcagc tccaacattg
      181 gaggttatta tgtgcagtgg taccagcagc ttccaggagc ggcccccaaa ctcctcatct
      241 atgaaaatga taaacgaccc tcaggggttt ctgatcgatt ctctggctcc cagtctgatt
      301 cctcagcctc cctgaccatc actggactcc agtctgagga tgaggctgat tattactgcc
      361 agtcctatga cagcagcttg agtgttgtgt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002004             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:10899:13340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002004
VERSION     KCWK01002004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10899:13340"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67742.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          156 c          120 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgttggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcggactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacgcaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002005             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:11598:8555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002005
VERSION     KCWK01002005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11598:8555"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67743.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          158 c          127 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtc cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaggca gctccaacat cggcagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctggccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002006             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:17291:11289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002006
VERSION     KCWK01002006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17291:11289"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67744.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       402..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           90 a          161 c          117 g          109 t
ORIGIN      
        1 acatgggggg tggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc aagcctatgc tgactcagcc ggcctccctc
      121 tctgcatctc ctggagcttc agccagtctc acatgcacct tcaccggtgg catcaatgtt
      181 gctgcctacc acatacactg gtaccagcag aagccaggga gtcctccccg gtatcttctg
      241 agatataaat cagactcaga taaggaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cctcagcgaa cacggggctt ttgcgcatct ctgggctcca gtctgaggat
      361 gaggctgact actactgtgc cattggacac agcagcggtg attacatctt cggtgctggg
      421 acccgcctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01002007             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:14568:5190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002007
VERSION     KCWK01002007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14568:5190"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..398
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67745.1"
                     /translation="DYYCSSYGGSNTLFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>470
                     /gene="IGLC"
BASE COUNT           90 a          151 c          120 g          109 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 actccctctg tgtccgggtc tcctggacag tcggtcacca tcacctgcac tggaaccagc
      181 agtgatattg ggtattatca tgctgtgtct tggtaccagc atcatccagg caaagccccc
      241 aaactcatga tttatgaggt caataaacgg cccgcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 gattattact gcagctcata tggaggcagc aatactttat tcttcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctttcccg
//
LOCUS       KCWK01002008             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:22695:14918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002008
VERSION     KCWK01002008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22695:14918"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67746.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          153 c          121 g          112 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca gtggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002009             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18505:13069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002009
VERSION     KCWK01002009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18505:13069"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67747.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           91 a          158 c          119 g          106 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcatctcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 gactaccaca tacactggta ccagcagaag ccagggagtc ccccccggta tcttctgaga
      241 tacagatcag actcagataa gggccagggc tctggagtcc ccagccggtt ctctggatcc
      301 aaagatgctg cagcgaacac agggatttta cgcatctctg ggctccagtc tgaggatgag
      361 gctgactatt actgtgccat tgggcacagc agcggtcctt acttcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01002010             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:20760:7560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002010
VERSION     KCWK01002010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20760:7560"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67748.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       396..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          143 c          139 g           97 t
ORIGIN      
        1 acatggggca gcctgacttt gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgctcacttt acaggctctg cggcctccta tgcggtgact
      121 cagccacgct cagtgtccgt gtccccagga caggcggcca ggatcacctg tgggggagac
      181 aacattggaa gtaaaagtgt ccagtggtac cagcagacgc caccgcaggc ccctgtactg
      241 gtcatttatg gtgataggga acggccctca gggatccctg aacgattctc tggctccaac
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggatag tagtagtaaa tatgtcttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002011             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:17151:11182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002011
VERSION     KCWK01002011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17151:11182"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..277
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67749.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       278..314
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           77 a          112 c           85 g           78 t
ORIGIN      
        1 acatggggga gcatcagcca gtctcacatg caccttcagc ggtggcatca atgttgctgc
       61 ctaccacata cactggtacc agcagaagcc agggagtccc ccccggtatc ttctgactta
      121 caaatcagac tcagataagg gccagggctc tggagtcccc agccgcttct ctggatccaa
      181 aaatgcttca acgaacacag gcattttaca catctctggg ctccagtctg aggatgaggc
      241 tgactatttc tgtgccattg gacacagcag cggtccttac atcttcggtg ctgggacccg
      301 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002012             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:14728:10476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002012
VERSION     KCWK01002012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14728:10476"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67750.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          158 c          125 g          109 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtctcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcggcatggg atgatagcct gagcggttac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01002013             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:24136:9359
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002013
VERSION     KCWK01002013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:24136:9359"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67751.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          162 c          118 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctata ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccatc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002014             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12927:12998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002014
VERSION     KCWK01002014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12927:12998"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..406
                     /note="immunoglobulin light chain variable region"
     V_region        58..406
     V_segment       58..369
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67752.1"
                     /translation="DYSCAIGHSSGPYIF"
     J_segment       370..406
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           91 a          154 c           98 g          101 t
ORIGIN      
        1 acatggggga ctcctctcct cctcctgctc ctctctcact gcacaggttc cctctccaag
       61 cctatgctga ctcagccggc ctccctctca gcaactcctg gagcatcagc cagtctcaca
      121 tgcaccttca gcggtggcat caatgttgct gactaccaca tacactggta ccagcagaag
      181 ccagggagtc ccccccggta tcttctgagt tacaaatcag actcagataa gggccagggc
      241 tctggagtcc ccagccgctt ctctggatcc aaaaatactt caacgaacac aggcatttta
      301 cacatctctg ggctccagtc tgaggatgag gctgactatt cctgtgccat tggacacagc
      361 agcggtcctt acatcttcgg tgctgggacc cggctcaccg tcctaggtca gcccaaggct
      421 tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01002015             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:7698:5136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002015
VERSION     KCWK01002015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7698:5136"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67753.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       391..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          149 c          136 g           92 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctatgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa tatgtgcact ggtaccagca gaagccagcg caggcccctg tgttggtcat
      241 ctatgctgat accagacggc cctcagggat ccctgagcga ttctctggct ccaactccgg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg tatgaggctg actatttctg
      361 tcaggtgtgg gacgatagta gtgatcatcc ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002016             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:18321:13940
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002016
VERSION     KCWK01002016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18321:13940"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67754.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       399..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           96 a          154 c          110 g          114 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcgcag cctgtgctga ctcagccaac ctccctctca
      121 gcatctcctg gagcatcagc cagactcacc tgcaccttga acagtggcat cagtgttgct
      181 aattacagga tattctggta ccaccagaag ccagggagtc ctccccggta tcttctgaac
      241 taccacacag actcagatat tcaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cggccaatgc agggatttta ctcatctctg gactccagtc tgaggatgag
      361 gctgactatt actgtatgat ctggcacaac aatgcttatt gggttttcgg cggagggacc
      421 cggctaaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002017             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:7908:4797
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002017
VERSION     KCWK01002017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7908:4797"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..274
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67755.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       277..314
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           75 a          106 c           90 g           81 t
ORIGIN      
        1 acatggggga gcatcagcca gtctcacatg caccttcagc ggtggcatca atgttgctga
       61 ctaccacgta cactggtatc agcagaagcc agggagtccc ccccggtatc ttctgaggta
      121 caaatcagac tcagataagg gcctgggctc tggagtcccc agccgcttct ctggatccaa
      181 agatgcttca gcgaatacag ggattttaca catctctggt ttccagtctg aggatgaggc
      241 tgactattac tgtgccattg gccacggcag cggtgattac atcttcgcta ctgggacccg
      301 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002018             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18320:19576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002018
VERSION     KCWK01002018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18320:19576"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67756.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          161 c          120 g          108 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcgtcaatg
      181 tgggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacca gtcagactca aggaagcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc tgttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccctatggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002019             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:16199:15445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002019
VERSION     KCWK01002019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16199:15445"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67757.1"
                     /translation="DYYCQSADSSGNHPLF"
     J_segment       393..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT          106 a          133 c          124 g          102 t
ORIGIN      
        1 aatgggggct gtggttctag gaggaagagc tctgggtgtc tcaccatgac ctggaccact
       61 gttctgctcc cctttctcac tctcttcaca ggctctgagg cctcctatga gctgacacag
      121 ccaccctcag tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagaaata
      181 ctggcaaaaa aatatgctca gtggttccag cagaagccag gccaggcccc tgtgttggtg
      241 atatataaag acagtgagag gccctcaggg atccctgaac gattctctag ttccagtaca
      301 gggacaacac ttaccttgac catcagtggg gcccaggtgg aagatgaggc tgactattac
      361 tgtcaatcag cagacagcag tggtaatcat ccgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002020             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:25152:14058
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002020
VERSION     KCWK01002020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:25152:14058"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67758.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           83 a          165 c          122 g          101 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggc
      181 cactacagct acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggttcttg
      241 atgtggctta agagtgatgg cagccacacc aagggggacg gggtccctga tcgcttctca
      301 ggctccagct ccgggcctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatatt ggcatttggg tattcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002021             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:21588:5456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002021
VERSION     KCWK01002021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:21588:5456"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67759.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          157 c          125 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca actccaacat cggaagtcat agtgtctcct ggtaccagca ggtcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002022             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11999:13739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002022
VERSION     KCWK01002022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11999:13739"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..277
                     /note="immunoglobulin light chain variable region"
     V_region        10..277
     V_segment       10..239
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <202..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67760.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       241..277
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>315
                     /gene="IGLC"
BASE COUNT           68 a           95 c           88 g           64 t
ORIGIN      
        1 acatggggga tcacctgtgg gggagacaac attggaagtc aaagtgtaca ctggtaccag
       61 cacaagccac cgcaggcccc tgttctgctc atcttttatt ataccgaacg gccctcagga
      121 atccctgagc gattctctgg ctccaaatca gggaacaccg ccaccctgac catcagcggg
      181 gtcgaggccg gggatgaggc tgactattac tgtcaggtgt gggacacaac tattgatcac
      241 ggcttgttcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      301 gtcactctct tcccg
//
LOCUS       KCWK01002023             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:13255:7441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002023
VERSION     KCWK01002023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:13255:7441"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67761.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          156 c          125 g          114 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cacttcacag ttccagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt cgccatctcc
      181 tgcactggga gcagctccaa cattggagat tattttgtgc agtggtacca gcaccttcca
      241 ggaacggccc ccaaactcct catctatgaa aataataagc gaccctcagg gatttctgat
      301 cgattctctg gctcccagtc tggaacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtttgattgc tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01002024             310 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:7145:9704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002024
VERSION     KCWK01002024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 310)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7145:9704"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    75..272
                     /note="immunoglobulin light chain variable region"
     V_region        75..272
     V_segment       75..236
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <200..>244
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67762.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       237..272
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        273..>310
                     /gene="IGLC"
BASE COUNT           55 a          102 c           77 g           76 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcacccccc aactcataat ttttgaggtc aataagcggc cctcaggggt
      121 ctctgatcgc ttctctggct ccaagtctgg caacacggcc tccctgacca tctctgggct
      181 ccaggctgag gatgaggctg attattactg ctgctcatat gtaggcagca acacttacat
      241 cttcgatgtt gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac
      301 tctgttcccg
//
LOCUS       KCWK01002025             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:12778:10644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002025
VERSION     KCWK01002025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12778:10644"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67763.1"
                     /translation="DYYCQSYDRSLNAVLF"
     J_segment       414..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           95 a          150 c          126 g          114 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatttcct
      181 gcaccgggag cagctccaac attggagatt attatgtgca gtggtaccag caggttccag
      241 gaacggcccc catactcctc atctatgaaa ataataagcg accctcaggg gcttccaatc
      301 gattctctgg ctcccagtct ggtacctcag cctcgctgac cataagtgga ctccagtctg
      361 aagatgaggc tgactattat tgtcagtctt atgacagaag tttaaatgct gttttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002026             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:24815:10352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002026
VERSION     KCWK01002026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:24815:10352"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67764.1"
                     /translation="DYFCQLFDTSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          164 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacac tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002027             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:28039:15695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002027
VERSION     KCWK01002027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:28039:15695"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67765.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          101 a          138 c          124 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctggg gcctcctatg aggtgacaca
      121 gtcaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagcaat
      181 actggcaaat aattatgctc agtggttcca gcagaagcca gaccaggccc ctgtgttggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcca gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gttgacagca gtgcccatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002028             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18115:10536
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002028
VERSION     KCWK01002028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18115:10536"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67766.1"
                     /translation="DYFCAAWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          160 c          122 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtccag ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaacca gctccaacat cggaagtaat agtgtgtcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat ctattataat catcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attatttctg cgcagcatgg gatgatagcc tgaccggtta cattttcggt
      421 cctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002029             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:16924:10887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002029
VERSION     KCWK01002029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16924:10887"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67767.1"
                     /translation="DYYCQSYDRSLSAVLF"
     J_segment       215..251
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           60 a           84 c           75 g           70 t
ORIGIN      
        1 acatggggga gattattatg tgcagtggta ccagcagctt ccaggaacgg cccccagact
       61 cctcatcttt gaaaataata agcgaccctc agggacttct gatcgattct ctggctccca
      121 gtctggtacc tcagcctcgc tgaccataag tgggctccag tctgaggatg aggctgacta
      181 ttactgccag tcttatgaca gaagcttgag tgctgtgtta ttcggagcag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002030             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:21382:19689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002030
VERSION     KCWK01002030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21382:19689"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..404
                     /note="immunoglobulin light chain variable region"
     V_region        87..404
     V_segment       87..370
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67768.1"
                     /translation="DYYCYSSDSNSKWLF"
     J_segment       376..404
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>446
                     /gene="IGLC"
BASE COUNT           96 a          139 c          115 g           96 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tagcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagatgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt cccgcagaag gcaggccagc cccctatggt gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aaggtgacta ctactgttac tcatcagaca
      361 gcaatagtaa atggctattc gacggaggga cccggctgac cgtcgtaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002031             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18361:13763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002031
VERSION     KCWK01002031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18361:13763"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..409
                     /note="immunoglobulin light chain variable region"
     V_region        79..409
     V_segment       79..370
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67769.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       372..409
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           82 a          144 c          115 g          106 t
ORIGIN      
        1 acatggggga cagtctccag catggcctgg tctcctctcc tcctcaccct tctcattcac
       61 tgcacagggt cctgggccca gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc
      121 gggcagaggg tcaccatctc ctgcactggg agcagctcca acattggagg ttattatgtg
      181 cagtggtacc agcagcttcc aggaacggcc cccaaactcc tcatctatga aaatgataaa
      241 cgaccctcag gggtttctga tcgattctct ggctcccagt ctgattcctc agcctccctg
      301 accatcactg gactccagtc tgaggatgag gctgattatt actgccagtc ctatgacagc
      361 agcttgagtg ttgtgttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002032             392 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:19897:16927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002032
VERSION     KCWK01002032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 392)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19897:16927"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    24..354
                     /note="immunoglobulin light chain variable region"
     V_region        24..354
     V_segment       24..319
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <282..>326
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67770.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       324..354
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        355..>392
                     /gene="IGLC"
BASE COUNT           78 a          124 c           99 g           91 t
ORIGIN      
        1 acatgggcac aggatcctgg gctcaggctg ccccgactca gactccctct gtgtccgggt
       61 ctcctggaca gtcggtcacc atctcctgca ctggaaccag cagtgatatt gggtattatc
      121 atgctgtgtc ttggtaccag catcatccag gcaaagcccc caaactcatg atttatgagg
      181 tcaataaacg gcccgcaggg gtctctgatc gcttctctgg ctccaagtct ggcaacacgg
      241 cctccctgac catctctggg ctccagactg aggatgaggc tgattattac tgcagctcat
      301 atgcaggcag caacacttta ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      361 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002033             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:22742:13277
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002033
VERSION     KCWK01002033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22742:13277"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67771.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          160 c          120 g          106 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgactacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 gatacagatc agactcagat aagggccagg gctctggagt cccccgccgc ttctctggat
      301 ccaaagatgc tgcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ctactgtgcc attgggcaca gcagcggtcc ttacttcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002034             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:18729:17650
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002034
VERSION     KCWK01002034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18729:17650"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..260
                     /note="immunoglobulin light chain variable region"
     V_region        4..260
     V_segment       4..224
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>232
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67772.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       228..260
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>298
                     /gene="IGLC"
BASE COUNT           67 a           85 c           87 g           59 t
ORIGIN      
        1 acatggggga gacaacattg gaactaaaac tgtgcactgg taccagcaga agccaccgca
       61 gggccctgta ttggtcatct ttgctgatag taaacggccc tcagggatcc ctgagcgatt
      121 ctctggctcc aactcaggga acaccgccac cctgaccatc agcagggtcg aggccgggga
      181 tgaggctgac tattactgtc aggtgtggga cagtagtagt aaatggatat tcggcggggg
      241 gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002035             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:14272:17798
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002035
VERSION     KCWK01002035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14272:17798"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67773.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          140 c          137 g          103 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct tggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002036             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:26009:15610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002036
VERSION     KCWK01002036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:26009:15610"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67774.1"
                     /translation="DYYCQVWDISSDHHVLF"
     J_segment       390..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          137 c          141 g           99 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacagac tctgtggcct cctatgatct gactcagcct
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagggaag ttgtgagctg gtaccagcag aagccaccgc aggcccctgt gctggtcatg
      241 tatgctgata gcgaacggcc ctcagggatc cctgagcgat tctctggctc gaaatcaggg
      301 aacacggcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acattagtag tgatcatcat gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002037             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:9857:8325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002037
VERSION     KCWK01002037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9857:8325"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67775.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          156 c          117 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacgtacac tggtatcagc ggaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc tgggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aatacaggaa ttttacacat ctctggtttc cagtctgagg
      361 atgaggctga ctattactgt gccattggcc acggtagcgg tgactacatc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002038             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:19219:2843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002038
VERSION     KCWK01002038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19219:2843"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67776.1"
                     /translation="DYYCQVWDNSNKYAIF"
     J_segment       398..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          143 c          135 g           98 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactttac aggctctgcg gcctcctatg aattgactca
      121 gccacgctca gtgtccgtgt ccccgggaca gacggccagg atcacctgtg ggggagacaa
      181 gattggaatt aaaagtgtac actggtacca gcagaggcca ccgcaggccc ctgtattggt
      241 catctatgtt gatggcgacc ggccctcagg gatccctgaa cgattctctg gttccaactc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggataata gtaataaata cgcgatcttc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002039             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:15451:17489
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002039
VERSION     KCWK01002039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15451:17489"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..408
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67777.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          164 c          115 g          117 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg acccagccaa
      121 cctccctctc agcatctccg ggagcatcag tcagactcag ctgcaccttg agcagtggca
      181 tcaatgttgg ttcttacacc atattctggt accagcagaa gccagggagt cctccccggt
      241 tccttctgta ctactactca gactcaaata atcaccaggg ctctggagtc cccagccgct
      301 tctctggatc caaagatgct tcagccaatg cagggctttt actgatctct gggctccagt
      361 ctgaagatga ggctgactat tactgtgcca tgtggcacag cagcgcttat gccttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002040             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:24844:10330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002040
VERSION     KCWK01002040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:24844:10330"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67778.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          160 c          117 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctctgcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgaggttcaa atcagactca gataaggacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcctcagcg aacacaggga ttttacgcat ctctgggatc cagtctgagg
      361 atgaggctga ctactactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccgcct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002041             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18266:5327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002041
VERSION     KCWK01002041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18266:5327"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..424
                     /note="immunoglobulin light chain variable region"
     V_region        106..424
     V_segment       106..389
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67779.1"
                     /translation="DYYCQVWDSDSKWVF"
     J_segment       391..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>465
                     /gene="IGLC"
BASE COUNT           91 a          147 c          137 g           90 t
ORIGIN      
        1 acatgggggg tctgggtctc aggaggcagc attgacggtg cctcagccat ggcctggacc
       61 cttctcctcc tcggcctcct cgcttactgc acaggctctg cgacctccta tgagctgact
      121 cagccaccct cagtgtcagc ggcctcagga cagacggcca ggatcacctg tggcggggac
      181 agccttggaa caaaatatgt gcactggtac cagcagaagc caacgcaggc ccctgtggtg
      241 gtcatctatg ctgataataa acggccctca gggatccctg agcgattctc tggctccaac
      301 tcagggaaca ccgccaccct gaccatcagc agggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tgatagtaag tgggtcttcg gcggagggac ccggctaacc
      421 gtcccaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002042             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:22423:10291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002042
VERSION     KCWK01002042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22423:10291"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67780.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          152 c          122 g          112 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagtg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002043             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18148:3515
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002043
VERSION     KCWK01002043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18148:3515"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..404
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67781.1"
                     /translation="DYYCSSYEGTNSFIF"
     J_segment       405..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           87 a          159 c          123 g          107 t
ORIGIN      
        1 acatgggggg ctggggtctc aggaggcagc gctctcagga cgtctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggacc ctgggctcag gctgccctga
      121 ctcagcctcc ctctgtgtct gggtctcccg gacagtcggt caccatctcc tgcacgggaa
      181 ccagcagtga catcggtggt tataactatg tctcctggta ccagcagcac ccaggcaaag
      241 cccccaaact catgatttat gatgtcagta agcggccctc aggggtctct gatcgcttct
      301 ctggctccaa atctggcaac acggcctccc tgaccatctc tgggctccag gctgaggatg
      361 aggctgatta ttactgcagc tcatatgaag gcaccaacag tttcatcttc ggtgttggga
      421 cccggctcac cgtactaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002044             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:5503:13231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002044
VERSION     KCWK01002044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5503:13231"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..265
                     /note="immunoglobulin light chain variable region"
     V_region        1..265
     V_segment       1..227
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67782.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       229..265
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           67 a           91 c           85 g           60 t
ORIGIN      
        1 acatgggggg gagacaacat tggaagtcaa agtgtgcact ggtaccagca caagccaccg
       61 caggcccctg tactggtcat cttttattat accgaacggc cctcaggaat ccctgagcga
      121 ttctctggct ccaaatcagg gaacaccgcc accctgacca tcagcggggt cgaggccggg
      181 gatgaggctg actattactg tcaggtgtgg gacacaacta ttgatcacgg cttattcgga
      241 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      301 ccg
//
LOCUS       KCWK01002045             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:12929:22569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002045
VERSION     KCWK01002045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12929:22569"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67783.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          150 c          115 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttggga gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002046             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:21693:19012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002046
VERSION     KCWK01002046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:21693:19012"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..274
                     /note="immunoglobulin light chain variable region"
     V_region        8..274
     V_segment       8..237
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <199..>246
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67784.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       238..274
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        275..>312
                     /gene="IGLC"
BASE COUNT           67 a           93 c           76 g           76 t
ORIGIN      
        1 acatggggca ctgggagcag ctccaacatt ggagattatt ttgtgcagtg gtaccagcac
       61 cttccaggaa cggcccccaa actcctcatc tatgaaaata ataagcgacc ctcagggatt
      121 tctgatcgat tctctggctc ccagtctgga acctcagcct ccctgaccat cactggactc
      181 cagtctgagg atgaggctga ttattactgc cagtcctatg acagcagttt gattgctgtg
      241 ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      301 actctcttcc cg
//
LOCUS       KCWK01002047             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:11861:15777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002047
VERSION     KCWK01002047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:11861:15777"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67785.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       416..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           95 a          157 c          123 g          109 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctctccttc tcactctgct ggttcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagcatctgg ggcccccgga cagagggtca ccatctcctg
      181 cattagcagc agctccaaca tcggggcggc ttattatgta tcctggtacc aacagttccc
      241 aggaacagcc cccaaactcc tcatctatga aaataataag cgaccctcag gggtttctga
      301 ccgattctct ggctccaagt ctggtccctc agcctccctg accatcactg gactccaatc
      361 tgaggatgag gctgattatt actgtttagc atgggatacc agcctgaatt ggatcttcgg
      421 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01002048             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:3880:18355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002048
VERSION     KCWK01002048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:3880:18355"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67786.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          157 c          124 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctactataat gatcaacggg gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagac tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002049             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:12296:4926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002049
VERSION     KCWK01002049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:12296:4926"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..450
                     /note="immunoglobulin light chain variable region"
     V_region        117..450
     V_segment       117..413
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67787.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       414..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           87 a          164 c          133 g          104 t
ORIGIN      
        1 acatgggggg cagtgtggct gcctcagcag agccctgagg agtctgcacc atggcctgga
       61 ccccaatcct cctcctcctc ctcactctcc tccttcactg cacagggtct ctctcccagc
      121 ctgtgctgac tcagtcgccc tctgcctctg cctccctggg agcctcggtc aagctcacct
      181 gcactctgag cagtggacac aggagctaca ccatcgcgtg gcatcagcag cagcaaggga
      241 aggcccctcg atacttgatg tggcttaaaa gtgatggcag ccacagcaag ggggacggga
      301 tccctgatcg cttctcaggc tccagctccg gggctgagcg ctacctcacc atctccaacc
      361 tccagtctga ggatgaggct gattattatt gtcagacgtg ggatattggc atttgggtgt
      421 tcggcggagg gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01002050             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:18665:14187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002050
VERSION     KCWK01002050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18665:14187"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..392
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67788.1"
                     /translation="DYYCQSYDSSLSGVLF"
     J_segment       397..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          150 c          124 g          107 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctcctct
       61 cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc tgacgcagcc
      121 gccctcagtg tctggggcgc ccgggcagag ggtcaccatc tcctgcagtg ggagcaactc
      181 caacattgga tactattatg tgcagtggta ccagcagctt ccagggacgg cccccaaact
      241 cctcatctat gaaaataata agcgaccctc tggggtttct gatcgattct ctggctccca
      301 gtctggtacc tcagcctccc tgaccatcac tggactccag tctgaggatg aggctgatta
      361 ttactgccag tcctatgaca gcagtttgag tggtgtctta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002051             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:4271:9162
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002051
VERSION     KCWK01002051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4271:9162"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67789.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          161 c          122 g          109 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc aggctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtaataaaaa catgtactgg taccaacaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaactaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002052             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:10817:20841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002052
VERSION     KCWK01002052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:10817:20841"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67790.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          150 c          116 g          107 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgacctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002053             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:24825:14716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002053
VERSION     KCWK01002053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24825:14716"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67791.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          157 c          125 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctccagtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002054             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:10394:3728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002054
VERSION     KCWK01002054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:10394:3728"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67792.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          157 c          118 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacgtacac tggtatcagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gagaagggcc tgggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aatacaggga ttttacacat ctctggcttc cagtctgagg
      361 atgaggctga ctattactgt gccattggcc acggcagcgg tgattacatc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002055             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:17531:19868
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002055
VERSION     KCWK01002055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17531:19868"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..213
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67793.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       219..251
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           58 a           84 c           91 g           56 t
ORIGIN      
        1 acatggggga agtgaagttg tgaactggta ccagcagaag ccagcgcagg cccctgtgct
       61 ggtcatctat gctgatagcg aacggccctc agggatccct gagcgattct ctggctccaa
      121 atcagggaac atggccaccc tgaccatcag cggggtcgag gccgggggtg aggctgacta
      181 ttactgtcag gtgtgggaca tgcgtagtga tcaaccgcta ttcggcggag ggacccggct
      241 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002056             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:20269:6444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002056
VERSION     KCWK01002056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20269:6444"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..408
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67794.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           97 a          165 c          112 g          109 t
ORIGIN      
        1 acatgggggc ccactgtggg gaaagaggct gtgtccacca tggcctggac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctccaagc ctatgctgac tcagccggcc
      121 tccctctcag caactcctgg agcatcagcc agtctcacat gcaccttcag cggtggcatc
      181 aatgttgctg cctaccacat acactggtac cagcagaagc cagggagtcc cccccggtat
      241 cttctgagtt acaaatcaga ctcagataag ggccagggct ctggagtccc cagccgcttc
      301 tctggatcca aaaatgcttc aacaaacaca ggcattttac acatctctgg gctccagtct
      361 gaggatgagg ctgactattt ctgtgccatt ggacacagca gcggtcctta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002057             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:25991:4589
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002057
VERSION     KCWK01002057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:25991:4589"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67795.1"
                     /translation="DYFCAAWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          158 c          121 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtccag ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaacca gctccaacat cggaagtaat agtgtatcct ggtaccagca gctcccagaa
      241 acgtctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attatttctg cgcagcatgg gatgatagcc tgaccggtta cattttcggt
      421 actgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002058             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:23348:5668
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002058
VERSION     KCWK01002058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23348:5668"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67796.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          127 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgctttc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002059             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:19675:6779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002059
VERSION     KCWK01002059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:19675:6779"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67797.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          147 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagtcaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttcttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002060             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:5693:18109
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002060
VERSION     KCWK01002060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5693:18109"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67798.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          150 c          115 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccaacaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002061             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:13971:2671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002061
VERSION     KCWK01002061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13971:2671"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..445
                     /note="immunoglobulin light chain variable region"
     V_region        112..445
     V_segment       112..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67799.1"
                     /translation="DYYCQSYDSNLSAMLF"
     J_segment       410..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          153 c          127 g          113 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagtagtt ccaacttcgg ggcgggttat tatgtgcact ggtaccagca acttccagga
      241 acggccccca aactcctcat ctatgaaaac aatatgcgac cctcaggggt ttctgatcga
      301 ttctctggct ccaagtctgg tacctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagtaatt tgagtgctat gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002062             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:21191:13676
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002062
VERSION     KCWK01002062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21191:13676"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..332
                     /note="immunoglobulin light chain variable region"
     V_region        8..332
     V_segment       8..288
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <260..>304
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67800.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       302..332
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        333..>370
                     /gene="IGLC"
BASE COUNT           76 a          116 c           92 g           86 t
ORIGIN      
        1 acatggggcc ccgactcaga ctccctctgt gtccgggtct cctggacagt cggtcaccat
       61 ctactgcact ggaaccagca gtgatattgg gtattatcat gctgtgtctt ggtaccaaca
      121 tcatccaggc aaagccccca aactcatgat ttatgaggtc aataaacggc ccgcaggggt
      181 ctctgatcgc ttctctggct ccaagtctgg caacacggcc tccctgacca tctctgggct
      241 ccagactgag gatgaggctg actattactg cagctcatat gcaggcagca acagtttatt
      301 cttcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac
      361 tctcttcccg
//
LOCUS       KCWK01002063             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:5480:13775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002063
VERSION     KCWK01002063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:5480:13775"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67801.1"
                     /translation="DYYCQVFDSSAVLL"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          161 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctata ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattaggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002064             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:20979:11775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002064
VERSION     KCWK01002064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20979:11775"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67802.1"
                     /translation="DYYCGAWDSSLSGYIF"
     J_segment       413..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           96 a          157 c          123 g          112 t
ORIGIN      
        1 acatggggga agctctgcct cagctgtgag cacagaaggc aggacttggg acaatcttca
       61 tcatgacctg gtcccctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtcct gacgcagccg ccctcagtgt ctgcggcccc agggcagaag gtcaccatct
      181 cctgctctgg aagtagttcc aacatcggga gaaattctgt ctcctggtac cagcaggtcc
      241 caggaacggc ccccaaactc ctcagttatg acaatgataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggttcct cagcctccct ggccatcact ggactccaga
      361 ctggagatga ggctgattat tactgcggag catgggatag cagtctgagt ggttacattt
      421 tcggtgctgg gacccaactc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCWK01002065             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:7441:15041
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002065
VERSION     KCWK01002065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7441:15041"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..403
                     /gene="IGLV5-104"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67803.1"
                     /translation="DYYCKIWHDSANVLF"
     J_segment       404..439
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           98 a          145 c          119 g          115 t
ORIGIN      
        1 acatggggga ctggcgtgtc agctgtgtcc accatggtct ggacatctct tctccttgtg
       61 cttctctccc actgcacagg ttctctctcc cagtctgtgc tgactcagcc accctccctc
      121 tctgcatccc tggaagcatt agccagactc acctgcaccc tgagcagtgg catcagtgtt
      181 ggtggaaaaa ttgtatactg gtaccagcag aagccaggga gcaatccccg gtatctcctg
      241 agctactact cagagtcaag taagcaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg gctcaactaa ctcagagatt ctgcacatct ctgggctgca gcctgaggat
      361 gaggctgact attattgtaa gatatggcat gacagcgcta atgtgttatt cggaggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002066             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:20254:6872
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002066
VERSION     KCWK01002066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20254:6872"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67804.1"
                     /translation="DYYCQVWDSSSDHWIF"
     J_segment       388..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          147 c          135 g           89 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacaga ctctgcgacc tcctatgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaaa tatgtgcact ggtaccagca gaggccaccg caggcccctg tgcaagtcat
      241 ctatactgat agcagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcgcggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtgatcattg gatattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002067             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12211:9068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002067
VERSION     KCWK01002067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12211:9068"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67805.1"
                     /translation="DYHCQVYDSSDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          161 c          122 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agtagtgacc
      181 tcagtgttgg aagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtatgacag tagtgatgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002068             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:16571:5786
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002068
VERSION     KCWK01002068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16571:5786"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67806.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       409..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           90 a          161 c          120 g          109 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggta gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aaataacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcaggtg tatgacagta gtgctgtatt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002069             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:6315:13238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002069
VERSION     KCWK01002069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:6315:13238"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67807.1"
                     /translation="DYYCASWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          158 c          119 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcatcatgg gatgataacc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002070             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:16993:7047
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002070
VERSION     KCWK01002070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16993:7047"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67808.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           92 a          142 c          132 g           95 t
ORIGIN      
        1 acatggggtg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag tctctgcgac ctcctatgaa ctgactcagt
      121 caccctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca
      181 ttggaattaa aactgtgcac tggtaccagc agaagccacc gcagggccct gtattggtca
      241 tctttgctga tagtaaacgg ccctcgggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002071             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:24789:6095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002071
VERSION     KCWK01002071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24789:6095"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..404
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67809.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       406..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           87 a          163 c          120 g          111 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt agtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt tctgccagct atttgacagt agtgttgtgt tcttcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01002072             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:21462:5524
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002072
VERSION     KCWK01002072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:21462:5524"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67810.1"
                     /translation="DYYCQVYDSSANVVF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           93 a          160 c          125 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagaaaaaag atgtactggt accagcagaa ggcagggagc gctcccaggt
      241 tatacctcta ctacgactcc gactcagaca aacagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagccttttt gttcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtggtattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002073             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:22508:19351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002073
VERSION     KCWK01002073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22508:19351"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67811.1"
                     /translation="DYSCAIGHSSGPYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           98 a          162 c          112 g          108 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcaa ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctgact accacataca ctggtaccag cagaagccag ggagtccccc ccggtatctt
      241 ctgagttaca aatcagactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaaa atacttcaac gaacacaggc attttacaca tctctgggct ccagtctgag
      361 gatgaggctg actattcctg tgccattgga cacagcagcg gtccttacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002074             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:15823:9112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002074
VERSION     KCWK01002074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15823:9112"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..440
                     /note="immunoglobulin light chain variable region"
     V_region        92..440
     V_segment       92..403
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67812.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       404..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           92 a          162 c          110 g          114 t
ORIGIN      
        1 acatggggac tgcagggaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc ccagcctgta ctgacccagc caacctccct
      121 ctcagcatct ccgggagcat cagccagact cagctgcacc ttgagcagtg gcatcaatgt
      181 tggtagttac agcgtattct ggtaccagca gaagccaggg agtcctcccc ggttccttct
      241 gtactactac tcagactcaa gtaaacacca gggctctgga gtccccagcc gcttctctgg
      301 atccaaagat gcttcggcca atgcaggcct tttactgatc tctaggctcc agtctgaaga
      361 tgaggctgac tattactgtg ccatatggca cagcagcgct tcttacttct tcggtactgg
      421 gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01002075             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:13637:10843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002075
VERSION     KCWK01002075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13637:10843"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67813.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          157 c          125 g          106 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagaaat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagcgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002076             284 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:11645:6357
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002076
VERSION     KCWK01002076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 284)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:11645:6357"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..246
                     /note="immunoglobulin light chain variable region"
     V_region        1..246
     V_segment       1..210
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <174..>218
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67814.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       214..246
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        247..>284
                     /gene="IGLC"
BASE COUNT           62 a           82 c           82 g           58 t
ORIGIN      
        1 acatgggaac taaaactgtg cactggtacc aacagaagcc accgcagggc cctgtattgg
       61 tcatctttgc tgatagtaga cggccctcag ggatccctga gcgattctct ggctccaatt
      121 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      181 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      241 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002077             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:22519:12059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002077
VERSION     KCWK01002077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22519:12059"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67815.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          157 c          118 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacatacac tggtaccagc agaagtcagg gagtcctccc cggtatcttc
      241 taagatacaa atcagactca gatcagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacgggga ttttacacgt ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002078             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:23558:17837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002078
VERSION     KCWK01002078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23558:17837"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..437
                     /note="immunoglobulin light chain variable region"
     V_region        92..437
     V_segment       92..400
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67816.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       401..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           94 a          162 c          108 g          111 t
ORIGIN      
        1 acatgggact gcagggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc ccagcctgtg ctgacccagc caacctccct
      121 ctcagcatct ccgggaacat cagccagact cagctgcacc ttgagcagtg gcaatgttgg
      181 tagttacagc atattctggt accagcagaa gccagggagt cctccccggt accttcttta
      241 ctactactca gactcaagta accaccagga ctctggagtc cccagccgct tctctggatc
      301 gaaagatgct tcagccaatg cagggctttt actgatctct gggctccagt ctgaagatga
      361 ggctgactat tactgtgcca catggcacag cagcgcttct tacatcttcg gtcctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002079             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:16881:16472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002079
VERSION     KCWK01002079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16881:16472"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..435
                     /note="immunoglobulin light chain variable region"
     V_region        93..435
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67817.1"
                     /translation="DYYCAIGLSSGYIF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>476
                     /gene="IGLC"
BASE COUNT           92 a          157 c          119 g          108 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgtac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacacacac tggtaccagc agaagccagg gaggcctccc cggtatcttc
      241 tgagatacaa atcagactca gataggggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgtttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc tcagcagcgg ttacatcttc ggtactggga
      421 cccggctcac cgtcccaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002080             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:13097:12053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002080
VERSION     KCWK01002080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13097:12053"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..411
                     /note="immunoglobulin light chain variable region"
     V_region        81..411
     V_segment       81..374
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67818.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       376..411
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           85 a          151 c          113 g          100 t
ORIGIN      
        1 acatggggag gacagtctcc agcatggcct cgtctcctct cctcctcacc cttctcattc
       61 actgcacagg gtcctgggcc cagtctgtgc tgacacagcc gccctcagtg tctggggccc
      121 cagggcagag ggtcaccatc tcctgcactg ggagcagctc caacattgga ggttattata
      181 tatcctggta ccagcagctc ccaggaacgg cccccaaact cctcgtctat gacaataata
      241 agcgaccctc aggggtttct gaccgattct ctggctccaa gtctggttcc tcagccaccc
      301 tgaccatcac tgggctccag actgaggatg aggctgatta ttactgccag tcctatgaca
      361 gcagtctgag tgctcgggta ttcggcggag ggacccggct aaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002081             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:13463:11620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002081
VERSION     KCWK01002081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13463:11620"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67819.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          142 c          142 g           91 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttggaagtga agttgtgaac tggtaccaga agaagccagc gcaggcccct gcactggtca
      241 tctatgctga tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagggggg tcgaggccgg gggtgaggct gactattact
      361 gtcaggtgtg ggacatgcgt agtgatcaac cgctattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002082             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11247:6421
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002082
VERSION     KCWK01002082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11247:6421"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67820.1"
                     /translation="DYYCSSYGGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          153 c          121 g          111 t
ORIGIN      
        1 acatgggggc ttggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatcacct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatggagg cagcaatact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002083             329 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:7452:5756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002083
VERSION     KCWK01002083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 329)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:7452:5756"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..291
                     /note="immunoglobulin light chain variable region"
     V_region        8..291
     V_segment       8..242
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67821.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       254..291
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>329
                     /gene="IGLC"
BASE COUNT           73 a           94 c           96 g           66 t
ORIGIN      
        1 acatgggagg acagacggcc aggatcacct gtgggggaga caacattgga attaaatttg
       61 tccactggta ccagcagaag ccagcgcagg cccctgtgaa ggtcatctat gctgatgaca
      121 aacggccctc agggatccct gagagattct ctggctccaa ttcagggaac accgccaccc
      181 tgaccatcag cggggtcgag gccggggatg aggctgacta ttcctgtcag gtgtgggaca
      241 gtgagactga tcattacatc ttcggtgttg ggacccggct caccgtccta ggtcagccca
      301 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002084             378 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:16812:9908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002084
VERSION     KCWK01002084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 378)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 378)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16812:9908"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..340
                     /note="immunoglobulin light chain variable region"
     V_region        13..340
     V_segment       13..300
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>312
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67822.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       304..340
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        341..>378
                     /gene="IGLC"
BASE COUNT           79 a          108 c          110 g           81 t
ORIGIN      
        1 acatgggcgg cctcctatga tctgactcag ccaccctcgg tgtcagtgtc cccaggaaag
       61 acggccagga tcacctgtgg gggagacaat attggaagtg aagttgtcaa ctggtaccag
      121 cagaagccac cgcaggcccc tgtggtggtc atctatgctg attatgaacg gccctcaggg
      181 atccctgagc gattctctgg ctccaaatca gggaacacgg ccaccctgac catcagcgga
      241 gtcgaggccg gggatgaggc tgactattac tgtcaggttt gggacattta tattgatcat
      301 ccggtgttat tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc
      361 tcggtcactc tcttcccg
//
LOCUS       KCWK01002085             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:17723:5485
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002085
VERSION     KCWK01002085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17723:5485"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..400
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67823.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       409..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           93 a          154 c          122 g          108 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc ggacagaggg tcaccatctc ctgcattagc
      181 agcagctcca acatcggggc ggcttattat gtatcctggt accaacagtt accaggaaca
      241 gcccccaaac tcctcatctt tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggtcc ctcagcctcc ctgaccatca ctggactcca atctgaggat
      361 gaggctgatt attactgttt agcatgggat accagcctga attggatctt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002086             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:16554:5528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002086
VERSION     KCWK01002086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16554:5528"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67824.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       396..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           94 a          150 c          115 g          110 t
ORIGIN      
        1 acatggggtc tggagccagg gatcccttcc aatatcagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctccagg gtccaattct caggctgtag tgactcagga
      121 gccctcaatg actgtgtccc caggagggac agtcactctc acctgtgctt ccagcactgg
      181 agcagtcacc agtggtcact ctccacactg gttccagcag aaacctggac aagcccccaa
      241 gacactgatt tataatacaa actacagaca ctcctggact cctgcccggt tctcaggctc
      301 cctccttggg ggtaaagctg ccctgacact gtcaggtgcg cagcctgagg atgaggctga
      361 gtattattgt ttactgtact atagtggtgc tcagctgtta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002087             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:19957:15646
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002087
VERSION     KCWK01002087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:19957:15646"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..445
                     /note="immunoglobulin light chain variable region"
     V_region        121..445
     V_segment       121..408
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67825.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       411..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          144 c          143 g          104 t
ORIGIN      
        1 acatgggaac gcagagtaca tgggggcctg actttgggaa gcagccttgg cggtgcctca
       61 gccatggccg ggacccttct cctcctcggc ctccttgctc actttacagg ctctgtggcc
      121 tcctatgagt tgcctcagcc acgctcagtg tccgtgtccc caggacagac ggccaggatc
      181 acctgtgggg gagacaacat tggaagtaat agtgtgcatt ggtaccagca gaagccaccg
      241 cgggcccctg tattggtcat ctctgttgat agcgaacggc cctcagggat ccctgagcga
      301 ttctctggtt ccagatcagg gaacaccgcc accctgacca tcagcggggt cgaggccggg
      361 gatgaggctg actattactg tcaggtgtgg gataatattt ataaatacgc ggtattcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002088             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:13046:12629
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002088
VERSION     KCWK01002088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13046:12629"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67826.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       398..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           86 a          156 c          123 g          104 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcatctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagcattgac aacggctttg tgtactggta ccagcagcgg ccgggcagcg ctcccaccac
      241 tgtgatttac aaagataacc aaagaccctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctgga ctgaaatctg aggacgaggc
      361 tgactattac tgtcagtctt atgacagcag cagtgtatta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002089             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:15683:12812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002089
VERSION     KCWK01002089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15683:12812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67827.1"
                     /translation="DYYCGAWDSSLSGYIF"
     J_segment       407..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          158 c          122 g          109 t
ORIGIN      
        1 acatggggct gcctcagctg tgagcacaga aggcaggact tgggacaatc ttcatcatga
       61 cctggtcccc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tcctgacgca gccgccctca gtgtctgcgg ccccagggca gaaggtcacc atctcctgct
      181 ctggaagtag ctccaacatc gggagaaatt ctgtctcctg gtaccagcag gtcccaggaa
      241 cggcccccaa actcctcagc tatgacaatg ataagcgacc ctcaggggtt tctgaccgat
      301 tctctggctc caagtctggt tcctcagcct ccctggccat cactggactc cagactggag
      361 atgaggctga ttattactgc ggagcatggg atagcagtct gagtggttac attttcggtg
      421 ctgggacccg actcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01002090             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:14019:7006
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002090
VERSION     KCWK01002090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14019:7006"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67828.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           98 a          153 c          111 g          117 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttgctaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcatc agggctctgg agtccacagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002091             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:14138:17249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002091
VERSION     KCWK01002091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14138:17249"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67829.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          162 c          122 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctt agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002092             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:19732:9092
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002092
VERSION     KCWK01002092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19732:9092"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..264
                     /note="immunoglobulin light chain variable region"
     V_region        6..264
     V_segment       6..226
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67830.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       232..264
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>302
                     /gene="IGLC"
BASE COUNT           63 a           86 c           96 g           57 t
ORIGIN      
        1 acatgggggg agacaagatt ggaagtgaag ttgtgaactg gtaccagcag aagccagcgc
       61 aggcccctgt gctggtcatc tatgctgata gcgaacggcc ctcagggatc cctgagcgat
      121 tctctggctc caaatcaggg aacacggcca ccctgaccat cagcggggtc gaggccgggg
      181 gtgaggctga ctattactgt caggtgtggg acatgcgtag tgatcaaccg ctattcggcg
      241 gagggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      301 cg
//
LOCUS       KCWK01002093             323 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:19767:16686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002093
VERSION     KCWK01002093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 323)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19767:16686"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..285
                     /note="immunoglobulin light chain variable region"
     V_region        5..285
     V_segment       5..249
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <213..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67831.1"
                     /translation="DYYCSSYAGTNTYIF"
     J_segment       250..285
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>323
                     /gene="IGLC"
BASE COUNT           69 a          103 c           75 g           76 t
ORIGIN      
        1 acatgggcac catctcctgc actggaacca gcagtgacat cggtggttat aactatgtct
       61 cctggtacca gcagcaccca ggcaaagccc ccaaattcat aatttatgat gtcagtaagc
      121 ggccctcagg ggtctctgat cgcttctctg gctccaaatc tggcaacacg gcctccctga
      181 ccatctctgg gctccaggct gaggatgagg ctgattatta ctgcagttca tatgcaggca
      241 ccaacactta catcttcggt gttgggaccc ggctcaccgt cctaggtcag cccaaggctt
      301 cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002094             363 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:12481:15011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002094
VERSION     KCWK01002094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 363)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12481:15011"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..325
                     /note="immunoglobulin light chain variable region"
     V_region        8..325
     V_segment       8..282
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <247..>297
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67832.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       288..325
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        326..>363
                     /gene="IGLC"
BASE COUNT           77 a          117 c           86 g           83 t
ORIGIN      
        1 acatgggcgc cctcagcatc tggggccccc gggcagaggg tcaccatctc ctgcactggg
       61 agcagctcca acatcggggc gggttattat gtatcctggt accagcagtt cccaggaaca
      121 gcccccaaac tcctcatcta tgaaaataat aaacgaccct caggggtttc tgaccgattc
      181 tctggctcca agtctggtac ctcagcctcc ctgaccatca ctggactcca atctgaggat
      241 gaggctgatt attactgctc agcatgggat agcagcctga gtatcaatta catcttcggt
      301 tctgggaccc gtctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      361 ccg
//
LOCUS       KCWK01002095             406 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:20820:16014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002095
VERSION     KCWK01002095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 406)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20820:16014"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..368
                     /note="immunoglobulin light chain variable region"
     V_region        87..368
     V_segment       87..332
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <296..>340
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67833.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       333..368
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        369..>406
                     /gene="IGLC"
BASE COUNT           88 a          122 c          108 g           88 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg acagacggcc aggatcacct gctctggaga
      121 agaattgcca aaaaaatatg cttattggtt ccagcagaag ccaggccagt cccctgtcca
      181 gatcatctat gaggacagta aacggccctc tgggatccct gagagattct ctggctccag
      241 ctcagggaca gtggccacct tgactatcac tggggcccag gtggaggatg aagctgacta
      301 ctactgtttc tcaacagaca ccagtggtaa tcgggtattc ggcggaggga cccgtctaac
      361 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002096             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20590:10912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002096
VERSION     KCWK01002096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20590:10912"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67834.1"
                     /translation="DYYCQVWDISSDHVLF"
     J_segment       375..411
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           86 a          135 c          130 g           98 t
ORIGIN      
        1 acatggggag cattgacggt gcctcagcca tggcctggac ttttctcctc ctcggcctcc
       61 ttgcttactg cacaggctcc gcggcctcct ttgatctgac tcagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gtggaggaga caacattgga agtgaacttg
      181 tgaactggta ccaacagagg ccaccgcagg cccctgtgct ggtcatgtat gctgatagcg
      241 aacggccctc agggatccct gagcgattct ctggctccaa atcagggaat acggccaccc
      301 tgaccatcag cggggtcgag gcctgggatg aggctgacta ttactgtcag gtgtgggaca
      361 ttagtagtga tcatgtgtta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002097             342 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:22041:19993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002097
VERSION     KCWK01002097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 342)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22041:19993"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..304
                     /note="immunoglobulin light chain variable region"
     V_region        8..304
     V_segment       8..267
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <232..>276
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67835.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       268..304
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        305..>342
                     /gene="IGLC"
BASE COUNT           72 a          105 c           86 g           79 t
ORIGIN      
        1 acatgggcag ccagactcag ctgcaccttg agcagtggca atgttggtag ttacagcata
       61 ttctggtacc agcagaagcc agggagtcct ccccggtacc ttctttacta ctactcagac
      121 tcaagtaacc accaggactc tggagtcccc agccgcttct ctggatcgaa agatgcttca
      181 gccaatgcag ggcttttact gatctctggg ctccagtctg aagatgaggc tgactattac
      241 tgtgccacat ggcacagcag cgcttcttac atcttcgggg gggggacccg gctcaccgtc
      301 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002098             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:22310:15093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002098
VERSION     KCWK01002098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22310:15093"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..438
                     /note="immunoglobulin light chain variable region"
     V_region        92..438
     V_segment       92..403
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67836.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>478
                     /gene="IGLC"
BASE COUNT           90 a          164 c          109 g          115 t
ORIGIN      
        1 acatgggact gcagggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc ccagcctgtg ctgacccagc caacctccct
      121 ctcagcatct ccgggagcat cagccagact cagctgcacc tttagcagtg gcatcaatgt
      181 tggtagttac agcatattct ggtaccagca gaagccaggg agtcctcccc ggtaccttct
      241 ctactactac tcagactcat ctaaacacca gggctctgga gtccccagcc gcttctctgg
      301 atccaaggat gcttcggcca atgcaggcct tttactgatc tctgggctcc agtctgaaga
      361 tgaggctgac tattactgtg ccatatggca cagcagcgct tcttacttct tcggtactgg
      421 gacccggctc accgtcctgg gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01002099             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:19390:4803
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002099
VERSION     KCWK01002099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19390:4803"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..404
                     /note="immunoglobulin light chain variable region"
     V_region        87..404
     V_segment       87..370
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67837.1"
                     /translation="DYYCYSSDNNSKCIF"
     J_segment       376..404
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>446
                     /gene="IGLC"
BASE COUNT           99 a          137 c          113 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tagcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagatgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt cccgcagaag gcaggccagc cccctatggt gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aaggtgacta ctactgttac tcatcagaca
      361 acaatagtaa atgtatattc gacggaggga cccggctgac cgtcgtaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002100             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:7028:9854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002100
VERSION     KCWK01002100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7028:9854"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67838.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          142 c          136 g           99 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gactctgcgg cctcctatga tctgactcag
      121 ccaccctcga tttcagtgtc cccaggacag acggccaggg tcacctgtgg gggagacaac
      181 atcggaggtg aagttgtgaa ttggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atctatgctg atagcgagcg gccctcaggg atcccggagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gagatgaggc tgactattac
      361 tgtcaggtgt gggaccttaa tagtcatcat ctgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002101             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:15588:22949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002101
VERSION     KCWK01002101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15588:22949"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..303
                     /note="immunoglobulin light chain variable region"
     V_region        118..303
     V_segment       118..266
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <228..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67839.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       267..303
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           58 a          109 c           95 g           79 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 attatagtga tcaacgagcc tctggtgtct ctgaccgatt ctctggcgct cagtctggca
      181 cgtcagcctc cctggccatc agtgggctcc agaccgagga tgaggctgat tattactgcg
      241 cagcatggga tgatagcctg agcggttaca tcttcggtgc tgggacccgg ctcgccgtcc
      301 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01002102             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:17683:11629
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002102
VERSION     KCWK01002102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:17683:11629"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..434
                     /note="immunoglobulin light chain variable region"
     V_region        110..434
     V_segment       110..391
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67840.1"
                     /translation="DYYCQVWDSTSDHYIF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          155 c          135 g           96 t
ORIGIN      
        1 acatgggggc cctgtctggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggcc tcctcgctca ctgcacaggc tctgcgacct cctatgagct
      121 gactcagcca ccctcggtgt cagcggcctc aggacagacg gccagggtca cctgtggggg
      181 agacaacatt ggaactacgt ttgtgcactg gtaccagcag aatccgccgc aggcccctgt
      241 gcaggtcctc tttgcggata acaaacggcc ctcagggatc cctgaacgat tctctggctc
      301 caactcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga
      361 ctattactgt caggtgtggg acagtactag tgatcattac atcttcggtg gtgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002103             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:19976:17832
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002103
VERSION     KCWK01002103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19976:17832"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..393
                     /note="immunoglobulin light chain variable region"
     V_region        63..393
     V_segment       63..358
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <321..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67841.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       360..393
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>431
                     /gene="IGLC"
BASE COUNT           79 a          138 c          109 g          105 t
ORIGIN      
        1 acatgggggt ctgggctctg ctcctcctca ccctcctcac tcagggcaca ggatcctggg
       61 ttcaggctgc cccgactcag cctccctctg tgtccgggtc tcctggacag tcggtcacca
      121 tctcctgcac tggaaccagc agtgatattg ggtattataa cgctgtgtct tggtaccaac
      181 agcatccagg caaagccccc aaactcataa tttttgacgt cattaagcgg ccctcagggg
      241 tctctgatcg cttctctggc tccaagtctg gcgacacggc ctccctgacc atctctgggc
      301 tccgggctga ggatgaggct gattattact gcagctcata tgcaggcaga aataattttt
      361 tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      421 ctctcttccc g
//
LOCUS       KCWK01002104             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:25546:8869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002104
VERSION     KCWK01002104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25546:8869"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..266
                     /note="immunoglobulin light chain variable region"
     V_region        8..266
     V_segment       8..229
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67842.1"
                     /translation="DYSCQVWDSESDYYIF"
     J_segment       230..266
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           66 a           85 c           90 g           63 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaattaa atttgtccac tggtaccagc agaagccagc
       61 gcaggcccct gtgaaggtca tctatgctga tgacaaacgg ccctcaggga tccctgagag
      121 attctctggc tccaattcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      181 ggatgaggct gactattcct gtcaggtgtg ggacagtgag agtgattatt acatcttcgg
      241 tggtgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      301 cccg
//
LOCUS       KCWK01002105             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:6570:18059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002105
VERSION     KCWK01002105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6570:18059"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..278
                     /note="immunoglobulin light chain variable region"
     V_region        5..278
     V_segment       5..238
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <206..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67843.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       241..278
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>316
                     /gene="IGLC"
BASE COUNT           67 a           99 c           81 g           69 t
ORIGIN      
        1 acatgggggc atcactgttg ctgcctacca catacactgg taccaacaga agccagggag
       61 tcctccccgg tatcttctga ggttcaaatc agactcagat aaggaccagg gctctggagt
      121 ccccagccgc ttctctggat ccaaagatgc ctcagcgaac acagggattt tacgcatctc
      181 tgggctccag tctgaggatg aggctgacta ctactgtgcc attgggcaca gcagcggtga
      241 ttacatcttc ggtgctggga cccgcctcac cgtcctaggt cagcccaagg cttcccccac
      301 ggtcactctg ttcccg
//
LOCUS       KCWK01002106             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:24305:16959
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002106
VERSION     KCWK01002106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:24305:16959"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67844.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          129 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac gaccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002107             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:8883:10557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002107
VERSION     KCWK01002107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:8883:10557"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67845.1"
                     /translation="DYYCASYEGSNTFLF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          157 c          121 g          106 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca gtggaaccag
      181 cactaagatt gggtatcaca atgctgtgtc ctggtaccaa gagcatccag gcaaagcccc
      241 caaactcatg atttttgacg tcaataagcg gtccacaggg atctctgatc ggttctctgg
      301 ctccaagtct ggcgacacgg cctccctgac catctctggg ctccaggctg atgatgaggc
      361 tgattattac tgcgcctcat atgaaggcag caacactttc ctcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002108             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:25183:10183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002108
VERSION     KCWK01002108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:25183:10183"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67846.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          160 c          121 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccggca cctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcggtta catcttcggt
      421 tctgggaccc gactcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002109             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:9958:12713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002109
VERSION     KCWK01002109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9958:12713"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67847.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          156 c          119 g          108 t
ORIGIN      
        1 acatgggggg gatctcacga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtcc ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcgggg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002110             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:14267:16719
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002110
VERSION     KCWK01002110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14267:16719"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..388
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67848.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       390..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          150 c          120 g          107 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accctctcct gcactgggag cagctccaac
      181 attggagatt attatgtgca gtggtaccag cagcttccag gaacggcccc caaactcctc
      241 atctatgaaa ataataagcg accctcaggg gtttctgatc gattctctgg ctcccagtct
      301 ggtacctcag cctccctgac catcactgga ctccagtctg acgatgaggc tgattattac
      361 tgtcagtcct atgatagcag cctgagtgtt gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002111             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:5909:10080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002111
VERSION     KCWK01002111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:5909:10080"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..401
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67849.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       404..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           87 a          157 c          130 g          102 t
ORIGIN      
        1 acatgggggg ctgtggctca ggaagcagag cctggagcgt ctccaccatg gcctgggctc
       61 cactcctcct caccctcctc gctcactgca cagggtcttg ggctgaggtt ctgttcacgc
      121 agccccattc tgtgtcgggg tctccggggc agacggtcac catctcctgt acccgcagca
      181 gaggcaacat tgacaatagt tatgtgcagt ggtaccagca gcgcccgggc agtgccccga
      241 ccacagtgat ttacagagat aaccaaagag cctctggggt ccctgatcgg ttctctggct
      301 ccatcgacag ctcctccaac tctgcctccc tcaccatctc tgggctgaag tctggggacg
      361 aggctgacta ctactgtcag tctactgatg gcaactacaa tcggttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002112             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:25293:11671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002112
VERSION     KCWK01002112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:25293:11671"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..261
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <233..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67850.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       275..305
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           71 a          102 c           88 g           82 t
ORIGIN      
        1 acatgggggg tctcctggac agtcggtcac catctcctgc actggaacca gcagtgatat
       61 tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc ccaaactcat
      121 gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg gctccaagtc
      181 tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg ctgattatta
      241 ctgtagctca tatgcaggca gcaacagttt attcttcgga ggagggaccc ggctgaccgt
      301 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002113             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:20886:18689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002113
VERSION     KCWK01002113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20886:18689"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..289
                     /note="immunoglobulin light chain variable region"
     V_region        8..289
     V_segment       8..253
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67851.1"
                     /translation="VYYCCSYTTSSTYIF"
     J_segment       254..289
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           62 a          106 c           78 g           81 t
ORIGIN      
        1 acatgggcgg tcaccttctc ctgcactgga accagcactg acgttggtgg ttataactct
       61 gtctcctggt accaacagga ccccggcaaa gcccccaaac tcatcattta tggtgtcagt
      121 aatcggccct caggggtctc tgatcgcttc tctggctcca agtctggcag cacggcctcc
      181 ctgaccatct ctgggctcca ggctgaggac gaggctgttt attactgttg ttcatataca
      241 accagtagca cttacatctt cggtgctggg acccggctaa ccgtcctagg tcagcccaag
      301 gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01002114             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:17318:17123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002114
VERSION     KCWK01002114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17318:17123"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67852.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           89 a          157 c          126 g          115 t
ORIGIN      
        1 acatggggct ctgcttcacc ggtgttgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tctccatctc
      181 ctgcactggg agcagctcca acattggaga tttttatgtg cagtggtacc agcaccttcc
      241 aggaacggcc cccaaactcc tcatctatga aaataataag cgaccctcag gggtttctga
      301 tcgattctct ggctcccagt ctggaacctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agtttgattg ctgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01002115             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:7099:10708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002115
VERSION     KCWK01002115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7099:10708"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67853.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           83 a          163 c          122 g          103 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggc
      181 cactacactt acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggttcttg
      241 atgtggctta agagtgatgg cagccatacc aagggggacg gggtccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatatt ggcatttggg tattcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002116             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:11646:21477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002116
VERSION     KCWK01002116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:11646:21477"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67854.1"
                     /translation="DYYCQMWGMTSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          141 c          141 g           94 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccaatga tctgactcag
      121 ccaacctcgg tgtcagagtc cccaggacag acggccagga tcacctgtgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atctctggtg atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcagatgt ggggcatgac tagtgatcat ccggtattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002117             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:4795:15473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002117
VERSION     KCWK01002117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:4795:15473"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67855.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       392..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          155 c          118 g          102 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctcgtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac acagccgccc
      121 tcagtgtctg gggccccagg gcagagggtc accatctcct gcactgggag cagctccaac
      181 attggaggtt attatatatc ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 gtctatgaca ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggttcctcag ccaccctgac catcactggg ctccagactg aggatgaggc tgattattat
      361 tgccagtcct atgacagcag tctgagtgct cgggtattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002118             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:12266:9817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002118
VERSION     KCWK01002118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12266:9817"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67856.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          157 c          116 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacgtacac tggtatcagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc tgggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aatacaggga ttttacacat ctctggtttc cagtctgagg
      361 atgaggctga ctattactgt gccattggcc acggcagcgg tgattacatc ttcgctactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002119             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:26111:19877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002119
VERSION     KCWK01002119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:26111:19877"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67857.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          162 c          109 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggtt
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002120             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18147:9248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002120
VERSION     KCWK01002120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18147:9248"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..437
                     /note="immunoglobulin light chain variable region"
     V_region        111..437
     V_segment       111..401
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67858.1"
                     /translation="DYYCQSADGNYRVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          165 c          121 g          103 t
ORIGIN      
        1 acatggggct ggctgtgact cagaaagcag agcctggggc gtctccacca tggcctgggc
       61 tccactcctc ctcaccctcc tcgctcactg cacagggtct tgggctgaac ttatgttcac
      121 tcagccccat tctgtgtcgg ggtctccggg gcagacggtc accatctcct gcacccgcag
      181 cattggcaac attgacagtg aatatgtgca gtggtaccag cagcgcccgg gcagtgcccc
      241 caccacactg atttacaaag atacccaaag accctctggg gtccctgatc ggttctctgg
      301 ctccatcgac agctcctcca actctgcctc cctcgccatc tctgggctac agtctgagga
      361 cgaggctgac tactactgtc agtctgctga tggcaactac agggtcttcg gcggagggac
      421 ccgtctaacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002121             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:16143:8425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002121
VERSION     KCWK01002121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16143:8425"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67859.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          151 c          121 g          111 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca cttagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002122             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:12327:12679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002122
VERSION     KCWK01002122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12327:12679"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67860.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       407..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           91 a          159 c          124 g          106 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tcgtctcctc tcctcctcac ccttttcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacacagc cgccctcagt gtctggggcc ccagggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg aggttattat atatcctggt accagcagct cccaggaacg
      241 gcccccaaac tcctcgtcta tgacaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggttc ctcagccacc ctgaccatca ctgggctcca gactgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagtctga gtgctcgggt attcggcgga
      421 gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002123             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:15059:12545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002123
VERSION     KCWK01002123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15059:12545"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67861.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       404..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          162 c          128 g           98 t
ORIGIN      
        1 acatggggga gcagagccct gaggagtctg caccatggcc tggaccccaa tcctcctcct
       61 cctcctcact ctcctccttc actgcacagg gtctctctcc cagcctgtgg tgactcagtc
      121 gtcctctgcc tctgcctccc tgggagcctc ggtcaagctc acctgcactc tgagcggtgg
      181 gcacagcgac tacaccatcg catggcatca gcagcagcaa gggaaggccc ctcggtattt
      241 gatgtggctt aaaagtgatg gcagccacag caagggggac gggatccctg atcgcttctc
      301 cggctccagc tccggggctg agcgctacct caccatctcc aacctccagt ctgaggatga
      361 ggctgattat tactgtcaga cctgggagac tggcattcag gtgttcggcg gagggacccg
      421 gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002124             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:14919:9822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002124
VERSION     KCWK01002124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14919:9822"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67862.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       411..447
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           93 a          157 c          127 g          108 t
ORIGIN      
        1 acatgggggc gcagcttcag ctgtgggtac agaaggcagg actcaggaca atctccagca
       61 tggcctggtt ccctctcgtc ctcaccctcc tcactcactg tgcagggtcc tgggcccagt
      121 ctgtgctgac tcagcctccc tcagcgtctg aggccgccag gaacagtgtc gccatctcct
      181 gttctggaag cagctccaac atcggaagtc atagtgtatc ctggtaccag cagctcccag
      241 gaacagctcc caaactcctc atctattatg atgatcaacg agcctcaggt gtctctgacc
      301 gattctctgg ctccaggtct ggcacgtcag cctccctggc catcagtggg ctccagaccg
      361 aggatgaggc tgattattac tgcgcagcat gggatgatag cctgagaggt tacatcttcg
      421 gtgatgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt
      481 tcccg
//
LOCUS       KCWK01002125             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:7191:14900
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002125
VERSION     KCWK01002125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:7191:14900"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..229
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <197..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67863.1"
                     /translation="DYFCAIGHSSGDYIF"
     J_segment       232..269
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           64 a           93 c           80 g           70 t
ORIGIN      
        1 acatggggtc gctggctacc acatacactg gtaccagctg aagccaggga gtcctcccca
       61 ctatcttctg agatacaaat cggactcaga taagggccag ggctctggag tccccagccg
      121 cttctctgga tccaaagatg cttcagcgaa cacagggatt ttacgcatct ctgggctcca
      181 gtctgaggat gaggctgact atttctgtgc cattgggcac agcagtggtg attacatctt
      241 cggtactggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      301 gttcccg
//
LOCUS       KCWK01002126             498 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:14201:6334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002126
VERSION     KCWK01002126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 498)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14201:6334"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..460
                     /note="immunoglobulin light chain variable region"
     V_region        130..460
     V_segment       130..423
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>432
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67864.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       424..460
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        461..>498
                     /gene="IGLC"
BASE COUNT           97 a          158 c          131 g          112 t
ORIGIN      
        1 acatggggag atttgggtga agcgcagctt cagctgtggg tacagaaggc aggactcagg
       61 acaatctcca gcatggcctg gttccctctc gtcctcaccc tcctcactca ctgtgcaggg
      121 tcctgggccc agtctgtgct gactcagcct ccctcagcgt ctgaggccgc caggaagagt
      181 gtcaccatct cctgttctgg gagcagctcc aacatcggaa gtcatagtgt atcctggtac
      241 cagcagctcc caggaacaac tcccaaactc ctcatctatt atagtgatca acgagcctca
      301 ggtgtctctg accgattctc tggctccaag tctggcacgt cagcctccct ggccatcagt
      361 gggctccaga ccgaggatga ggctgactat tactgcgcag catgggatga tagcctgagc
      421 ggttacatct tcggtgttgg gacccggctc accgtcctag gtcagcccaa ggcttccccc
      481 acggtcactc tgttcccg
//
LOCUS       KCWK01002127             497 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:7106:12650
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002127
VERSION     KCWK01002127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 497)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 497)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..497
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7106:12650"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    129..459
                     /note="immunoglobulin light chain variable region"
     V_region        129..459
     V_segment       129..421
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>431
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67865.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       423..459
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        460..>497
                     /gene="IGLC"
BASE COUNT           99 a          159 c          126 g          113 t
ORIGIN      
        1 acatggggga tttgggtgaa gcgcagcttc agctgtgggt acagaaggca ggactcagga
       61 caatctccag catggcctgg ttccctctcg tcctcaccct cctcactcac tgtgcagggt
      121 cctgggccca gtctgtgctg actcagcctc cctcagcgtc tgaggccgcc aggaagagtg
      181 tcaccatctc ctgttctgga agcacctcca acatcggaag caataatgta tcctggtacc
      241 agcagctccc aggaacagct cccaaactcc tcttttatta taatgatcaa cgagcctcag
      301 gtgtctctga ccgattctct tgctccaagt ctggcacgtc agcctccctg gccatcagtg
      361 ggctccagac cgaggatgag gctgattatt actgcgcagc atgggatgat aacctgagcg
      421 gctacatctt cggtgctggg acccggctca ccgtcctagg tcagcccaag gcttccccca
      481 cggtcactct gttcccg
//
LOCUS       KCWK01002128             515 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:7929:8567
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002128
VERSION     KCWK01002128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 515)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 515)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..515
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:7929:8567"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    153..477
                     /note="immunoglobulin light chain variable region"
     V_region        153..477
     V_segment       153..440
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <402..>449
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67866.1"
                     /translation="DYYCQSSHSRVNHPFF"
     J_segment       447..477
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        478..>515
                     /gene="IGLC"
BASE COUNT          116 a          151 c          142 g          106 t
ORIGIN      
        1 acatgggggc cccaaaagcc tgagagggaa taagagcggc ctggggagcc cagctgtgct
       61 gtggttctag gaggaagacc tctgggtgtc tcaccatgac ctggaccact gttctgctcc
      121 cctttctcac tctctgcaca ggctctgagg cctcctatga gctgacacag ccaccctcag
      181 tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagaaaca ctggcaaaaa
      241 aatatgctca gtggttccag cagaagccag gccaggcccc tgtgttggtg atatataaag
      301 acagtgagag gccctcaggg atccctgagc gattctctag ctccagttca gggacaacag
      361 ttaccttgac catcagtggg gcccaggcag aagatgaggc tgactattac tgtcaatcat
      421 cgcacagcag ggttaatcat ccgtttttcg gaggagggac ccggctgacc gtcctaggtc
      481 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002129             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:12720:8817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002129
VERSION     KCWK01002129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12720:8817"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67867.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          155 c          119 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagtatctcc tggagcatca gccagtctca catgcacctt cggcggtggc atcaatgttg
      181 ctggctacca catacactgg taccaacaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt caccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtga ttacatcttc ggtgctggga
      421 cccgactcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002130             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:10920:6235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002130
VERSION     KCWK01002130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:10920:6235"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67868.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          148 c          130 g           95 t
ORIGIN      
        1 acaggggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttcttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002131             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:14368:16864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002131
VERSION     KCWK01002131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14368:16864"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..269
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67869.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       272..306
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           70 a          105 c           91 g           78 t
ORIGIN      
        1 acatgggagc cagactcaac tgcaccttga gcagtggcgt caatgtgggt agttacagca
       61 tattctggta ccagcagaag ccagggagtc ctccccggta ccttctgtac taccagtcag
      121 actcaaggaa gcaccagggc tctggagtcc ccagccgctt ctctggatcc aaagatgctt
      181 cagccaatgc agggctgtta ctgatctctg ggctccagtc tgaagatgag gctgactatt
      241 actgtgccct atggcacagc agcgcttctt gcatcttcgg tggtgggacc cggctcaccg
      301 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01002132             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:24158:10090
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002132
VERSION     KCWK01002132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24158:10090"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67870.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       403..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           84 a          161 c          127 g           99 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtggt gactcagtcg
      121 tcctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcggtggg
      181 cacagcgact acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggtatttg
      241 atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctga tcgcttctcc
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggagact ggcattcagg tgttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ctctcggtca ctctcttccc g
//
LOCUS       KCWK01002133             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:26821:7249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002133
VERSION     KCWK01002133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:26821:7249"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..440
                     /note="immunoglobulin light chain variable region"
     V_region        114..440
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67871.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>482
                     /gene="IGLC"
BASE COUNT           88 a          156 c          127 g          111 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtctcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc tcagtctggc acgtcagcct ccctggccat cagtgggctc caggccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagtct gagcggttac atcttcggtg
      421 ctgggacccg gctcgccgtc gtaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01002134             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16109:18532
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002134
VERSION     KCWK01002134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16109:18532"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..274
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67872.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       277..314
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           72 a          106 c           95 g           79 t
ORIGIN      
        1 acatggggga gcatcagcca gtctcacatg caccttcagc ggtggcatca atgttgctgg
       61 ctaccacata cactggtacc agcagaagtc tgggagtcct ccccggtatc ttctaagata
      121 caaatcagac tcggatcagg gccagggctc tggggtcccc agccgcttct ctggatccaa
      181 agatgcttca gcgaacacgg ggattttaca cgtctctggg ctccagtctg aggatgaggc
      241 tgactattac tgtgccattg ggcacagcag cggtgattac atcttcggtg ctgggacccg
      301 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002135             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:9799:6223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002135
VERSION     KCWK01002135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9799:6223"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..453
                     /note="immunoglobulin light chain variable region"
     V_region        117..453
     V_segment       117..410
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67873.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       416..453
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           94 a          158 c          129 g          110 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac atcggggcgg gttattatgt atcctggtac cagcagttcc
      241 caggagcagc ccccaaactc ctcatctatg aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtgcct cagcctccct gaccatcact ggactccaat
      361 ctgaggatga ggctgattat tactgctcag catgggatag cagcctgagt atcaattaca
      421 tcttcggtgc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      481 ctctgttccc g
//
LOCUS       KCWK01002136             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:25076:9270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002136
VERSION     KCWK01002136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:25076:9270"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..434
                     /note="immunoglobulin light chain variable region"
     V_region        86..434
     V_segment       86..397
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67874.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       400..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          159 c          118 g          107 t
ORIGIN      
        1 acatgggggg aaagaggctg tgtccaccat ggcctggact cctctcctcc tcctgctcct
       61 ctctcactgc acaggttccc tctcccagcc tgtgctgacc cagccaacct ccctctcagc
      121 atctccggga gcatcagcca gactcagctg caccttgagc agtggcgtca atgtgggtag
      181 ttacagcata ttctggtacc agcagaagcc agggagtcct ccccggtacc ttctgtacta
      241 ccagtcagac tcaaggaagc accagggctc tggagtcccc agccgcttct ctggatccaa
      301 agatgcttca gccaatgcag ggctgttact gatctctggg ctccagtctg aagatgaggc
      361 tgactattac tgtgccctat ggcacagcag cgcttcttgc atcttcggtg gtgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002137             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:21592:5079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002137
VERSION     KCWK01002137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21592:5079"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67875.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          150 c          117 g          107 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 cgccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002138             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:12875:15362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002138
VERSION     KCWK01002138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12875:15362"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67876.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          141 c          135 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccacgatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaggccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002139             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:20812:15661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002139
VERSION     KCWK01002139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:20812:15661"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67877.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          160 c          124 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagag gccagggagc gctcccaggt
      241 tattcctgta ttactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaggtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggacagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002140             339 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:12444:10583
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002140
VERSION     KCWK01002140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 339)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12444:10583"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..301
                     /note="immunoglobulin light chain variable region"
     V_region        8..301
     V_segment       8..261
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <229..>273
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67878.1"
                     /translation="DYYCGLGHSSGDYIF"
     J_segment       264..301
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        302..>339
                     /gene="IGLC"
BASE COUNT           74 a          103 c           87 g           75 t
ORIGIN      
        1 acatggggtc tcacatgcac cttcacgggt ggcatcaatg ttgctgacta ccacatacac
       61 tggtaccagc agaagccagg gagtcccccc cggtatcttc tgaggtacaa atcagactca
      121 gataagggcc agggctctgg agtccccagc cgcttctctg gatccaaaga tgcttcagcg
      181 aacacaggga ttttacacat ctctggactc cagtctgagg atgaggctga ctattactgt
      241 ggccttgggc acagcagcgg tgattacatc ttcgctgatg ggacccggct caccgtccta
      301 ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002141             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:6155:11617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002141
VERSION     KCWK01002141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:6155:11617"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67879.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       408..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          154 c          128 g          112 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg cttcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agcatctggg gcccccgggc agagggtcac catctcctgc
      181 tctgggagca gctccaacat cggggcgggt ttttatgtat cctggtacca gcagttccca
      241 ggaacagccc ccaaactcct catctttgaa aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggttcctca gcctccctga ccatcactgg actccaatct
      361 gaggatgagg ctgattatta ttgttcatca tgggaaagca gcctgaattg ggtattcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002142             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:22889:17048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002142
VERSION     KCWK01002142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22889:17048"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..409
                     /note="immunoglobulin light chain variable region"
     V_region        79..409
     V_segment       79..372
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67880.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       373..409
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           87 a          147 c          111 g          102 t
ORIGIN      
        1 acatgggggg acatctccac catggcctgg gatctgctcc tcttcaccct cctcactcag
       61 ggcacaggat cctgggctca ggctgccctg actcagcctc cctcaatgtc tgggtctcct
      121 ggacagtcgg tcaccatctc ctacactgga accagcagtg acattggtgg ttataaccgt
      181 gtctcctggt accaacagca cccaggcaaa gaccccaaat tcatgattta tgaggtcagt
      241 caacggccct caggggtctc tgatcgtatc tctggctcca agtctggcaa cacggcctcc
      301 ctgaccatct ctgggctcca gactgaggat gaggctggtt attactgcag ctcatttgca
      361 ggtaccaaca ctggcttaat cggtggaggg acccggctga ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002143             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:20151:17054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002143
VERSION     KCWK01002143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20151:17054"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..433
                     /note="immunoglobulin light chain variable region"
     V_region        104..433
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67881.1"
                     /translation="DYYCSSFAGRNSFFF"
     J_segment       404..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>472
                     /gene="IGLC"
BASE COUNT           84 a          155 c          120 g          113 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatctt gggtatttta atgctgtgtc ttggtaccaa caacatccag gcaaagcccc
      241 caaactcatg atttatgacg tcactaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagttcat ttgccggcag gaacagtttc tttttcggag gagggacccg
      421 gctgaccgtc ctaagtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002144             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:22458:9353
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002144
VERSION     KCWK01002144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22458:9353"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67882.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          155 c          120 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg agttcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgactat tactgcagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002145             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:14184:6251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002145
VERSION     KCWK01002145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14184:6251"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67883.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       392..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           92 a          140 c          138 g           97 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgc ggcctcctat gaactgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taaaagtgtg cagtggtacc agcagacgcc accgcaggcc cctatactgg
      241 tcatttatgg tgatagggaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggatagt agtagtaaat atgtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002146             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:15276:10886
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002146
VERSION     KCWK01002146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15276:10886"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67884.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          160 c          125 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgtt ctaccagtcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gttcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgcaaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcacactct
      481 tcccg
//
LOCUS       KCWK01002147             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:8812:3741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002147
VERSION     KCWK01002147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8812:3741"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67885.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          141 c          136 g          102 t
ORIGIN      
        1 acatggggcc tgactttggg aagcagcctt ggcggtgcct cagccatggc cgggaccctt
       61 ctcctcctcg gcctccttgc tcactttaca ggctctgtgg cctcctatga gttgcctcag
      121 ccacgctcag tgtccgtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta atagtgtgca ttggtaccag cagaagccac cgcgggcccc tgtattggtc
      241 atctctgttg atagcgaacg gccctcaggg atccctgagc gattctctgg ttccagatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggataatat ttataaatac gcggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002148             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:10445:14130
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002148
VERSION     KCWK01002148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:10445:14130"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67886.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          148 c          130 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gtactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccatggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002149             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:21069:9814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002149
VERSION     KCWK01002149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21069:9814"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..449
                     /note="immunoglobulin light chain variable region"
     V_region        101..449
     V_segment       101..412
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67887.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           90 a          159 c          126 g          112 t
ORIGIN      
        1 acatggggct gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgg tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcactc tgagtagtga
      181 cctcagtgtt ggtggtaaaa acatgtactg gtaccagcag aagccaggga gcgctcccag
      241 gttattcctg ttctaccagt ccgactcaga caagcagctg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctggactcca
      361 gcctgaggac gaggccgatt attactgtca ggtgtatgac agtagtgcaa atgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01002150             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:15245:17241
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002150
VERSION     KCWK01002150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:15245:17241"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    44..392
                     /note="immunoglobulin light chain variable region"
     V_region        44..392
     V_segment       44..353
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <320..>364
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67888.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       355..392
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>430
                     /gene="IGLC"
BASE COUNT           88 a          138 c           97 g          107 t
ORIGIN      
        1 acatgggctc ctgctcctct ctcactgcac aggttccctc tcgcagcctg tgctgactca
       61 gccaacctcc ctctcagcat ctcctggagc atcagccaga ctcacctgca ccttgaacag
      121 tggcatcagt gttgctaatt acaggatatt ctggtaccac cagaagccag ggagtcctcc
      181 ccggtatctt ctgaactacc acacagactc agatattcat cagggctctg gagtccccag
      241 ccgcttctct ggatccaaag atgcttcggc caatgcaggg attttactca tctctggact
      301 ccagtctgag gatgaggctg actattactg tatgatttgg cacaacaatg cttattgggt
      361 tttcggcgga gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac
      421 tctcttcccg
//
LOCUS       KCWK01002151             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:18803:11477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002151
VERSION     KCWK01002151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18803:11477"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67889.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           93 a          159 c          114 g          107 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtgac aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttag tgatctctgg gctccagtcc gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggg ggggggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002152             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:2354:14106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002152
VERSION     KCWK01002152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:2354:14106"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67890.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          160 c          116 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 ctgcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatataaatc agactcagat aaggaccagg actctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ctcagcgaac acggggcttt tgcacatctc tgggctccag tctgaggatg
      361 aggctgacta ctactgtgcc attgggcaca gcagcggtga ttacatcttc ggtgctggga
      421 cccgcctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002153             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:18841:5532
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002153
VERSION     KCWK01002153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18841:5532"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..440
                     /note="immunoglobulin light chain variable region"
     V_region        92..440
     V_segment       92..403
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67891.1"
                     /translation="DYSCAIGHSSGPYIF"
     J_segment       404..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           97 a          161 c          112 g          108 t
ORIGIN      
        1 acatgggggt gtggggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc caagcctatg ctgactcagc cggcctccct
      121 ctcagcaact cctggagcat cagccagtct cacatgcacc ttcagcggtg gcatcaatgt
      181 tgctgactac cacatacact ggtaccagca gaagccaggg agtccccccc ggtatcttct
      241 gagttacaaa tcagactcag ataagggcca gggctctgga gtccccagcc gcttctctgg
      301 atccaaaaat acttcaacga acacaggcat tttacacatc tctgggctcc agtctgagga
      361 tgaggctgac tattcctgtg ccattggaca cagcagcggt ccttacatct tcggtgctgg
      421 gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01002154             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16582:11401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002154
VERSION     KCWK01002154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16582:11401"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67892.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       398..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          155 c          116 g          115 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaagct gccccgactc
      121 agcctccctc tgtgtccggg tctcctgggc agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtcttat aatgctgtgt cttggtacca acaacatcca ggcaaagccc
      241 cccaactcat aatttttgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatttctgg gctccaggct gaggatgagg
      361 ctgattatta ctgctgctca tatgtaggca gcaacactta catcttcgat gttgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002155             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:10148:4821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002155
VERSION     KCWK01002155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10148:4821"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67893.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          160 c          115 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgttgccta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagagcc agggcgctgg agtccccagt cgcttctctg
      301 gatccaataa tgcttcagcg aacacaggga ttttacgcat ctctggcctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tccttacatc ttcggtgctg
      421 ggacccgtct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002156             278 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:14258:20194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002156
VERSION     KCWK01002156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 278)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14258:20194"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..240
                     /note="immunoglobulin light chain variable region"
     V_region        8..240
     V_segment       8..201
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <171..>212
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67894.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       203..240
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        241..>278
                     /gene="IGLC"
BASE COUNT           54 a           85 c           76 g           63 t
ORIGIN      
        1 acatgggcca gcagaagcca gggagcgctc ccaggttatt cctgtactac tactccgact
       61 cagacaagca gctgggacct ggggtcccca atcgagtctc tggctccaag gagacctcaa
      121 gtaacacagc gtttttgctc atctctgggc tccagcctga ggacgaggcc gattatttct
      181 gccaggtgtt tgacagtagt gttgtgttct tcggaggagg gacccgactg accgtcctag
      241 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002157             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:13849:3244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002157
VERSION     KCWK01002157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13849:3244"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..401
                     /note="immunoglobulin light chain variable region"
     V_region        74..401
     V_segment       74..361
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <323..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67895.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       365..401
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>439
                     /gene="IGLC"
BASE COUNT           85 a          132 c          123 g           99 t
ORIGIN      
        1 acatggggcc tcagccatgg cctggacttt tctcctcctc ggcctccttg cttactgcac
       61 aggctctgcg gcctcctatg atctgactca gccaccctcg gtgtcagtgt ccccaggaaa
      121 gacggccagg atcacctgtg ggggagacaa tattggaagt gaagttgtca actggtacca
      181 gcagaagcca ccgcaggccc ctgtggtggt catctatgct gattatgaac ggccctcagg
      241 gatccctgag cgattctctg gctccaaatc agggaacacg gccaccctga ccatcagcgg
      301 agtcgaggcc ggggatgagg ctgactatta ctgtcaggtt tgggacattt atattgatca
      361 tccggtgtta ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc
      421 ctcggtcact ctcttcccg
//
LOCUS       KCWK01002158             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:9084:16203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002158
VERSION     KCWK01002158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:9084:16203"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..400
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67896.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       401..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           93 a          159 c          111 g          112 t
ORIGIN      
        1 acatggggga gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccca gcctgtgctg acccagccaa cctccctctc
      121 agcatctccg ggagcatcag ccagactcag ctgcaccttg agcagtggca tcaatgttgg
      181 tagttacagc atattctggt accagcagaa gccagggagt cctccccggt accttctgta
      241 ctactactca gactcaagta aacaccagga ctctggagtc cccagccgct tctctggatc
      301 caaagatgct tcggccaatg caggcctttt agtgatctct gggctccagt ctgaagatga
      361 ggctgactat tactgtgcca tatggcacag cagcgcttct tacttcttcg gtactgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002159             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:18656:4083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002159
VERSION     KCWK01002159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18656:4083"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67897.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          160 c          112 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtcctta caccatattc tggtacaagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcaggac ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002160             278 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:21787:3600
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002160
VERSION     KCWK01002160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 278)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21787:3600"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..240
                     /note="immunoglobulin light chain variable region"
     V_region        8..240
     V_segment       8..200
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <168..>212
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67898.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       207..240
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        241..>278
                     /gene="IGLC"
BASE COUNT           60 a           82 c           74 g           62 t
ORIGIN      
        1 acatggggca gaagccaggg agtccccccc ggtatcttct gaggtacaaa tcagactcag
       61 ataagggcca gggctctgga gtccccagcc gcttctctgg atccaaagat gcttcagcga
      121 acacagggat tttacgcata tctggactcc agtctgagga tgaggctgac tattactgtg
      181 ccattggaca cagcagcggt gattatatct tcggtgctgg gacccgtctc accgtcctag
      241 gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01002161             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:7219:19815
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002161
VERSION     KCWK01002161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7219:19815"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67899.1"
                     /translation="DYYCSSYAGRNSFLF"
     J_segment       400..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          157 c          121 g          111 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggttg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatgtt ggctattctc atgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 caaactcatg atttatgatg tcactaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaaggct ggcaacacgg cctccctcac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag gaactctttc ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002162             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:15052:19486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002162
VERSION     KCWK01002162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15052:19486"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67900.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          156 c          119 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catacactgg taccagcaga agtcagggag tcctccccgg tatcttctaa
      241 gatacaaatc agactcagat cagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaggatgc ttcagcgaac acggggattt tacacgtctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacaca gcagcggtga ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002163             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:23497:5035
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002163
VERSION     KCWK01002163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:23497:5035"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67901.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           98 a          142 c          121 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cttactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaagaatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tccagatcat
      241 ctatgaggac agtaaacggc cctctgggat ccctgagaga atctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 tttctcaaca gacaccagtg gtaatcgggt attcggcgga gggacccgtc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002164             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:13271:11119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002164
VERSION     KCWK01002164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13271:11119"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67902.1"
                     /translation="DYYCAVWSSSAYIF"
     J_segment       400..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           82 a          156 c          118 g          117 t
ORIGIN      
        1 acatgggggc ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctgtcac agcctgtgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gtcagactca cctgcacctt gcgcactggc ctcaatgttg
      181 gtggctacta catattctgg taccagcaga agccagggag tcctccccgg ttccttctga
      241 attactactc agactcaaat cagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgt ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc gtttggtcca gcagcgctta catcttcggt ggtgggactc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002165             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:7874:3751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002165
VERSION     KCWK01002165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7874:3751"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67903.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          156 c          126 g          112 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggagatt attatgtgca gtggtaccag caccttccag
      241 gaacggcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggaacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag tttgattgct gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002166             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:11603:9121
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002166
VERSION     KCWK01002166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:11603:9121"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67904.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       394..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           95 a          150 c          114 g          108 t
ORIGIN      
        1 acatggggga gccagggatc ccttccaata tcagcaccat ggcctggact ctgctcctcc
       61 tccagttcct cctcacttgc tgcccagggt ccaattctca ggctgtagtg actcaggagc
      121 cctcaatgac tgtgtcccca ggagggacag tcactctcac ctgtgcttcc agcactggag
      181 cagtcaccag tggtcactct ccacactggt tccagcagaa acctggacaa gcccccaaga
      241 cactgattta taatacaaac tacagacact cctggactcc tgcccggttc tcaggctccc
      301 tccttggggg taaagctgcc ctgacactgt caggtgcgca gcctgaggat gaggctgagt
      361 attattgttt actatactat agtggtgctc agctgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002167             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:22435:16374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002167
VERSION     KCWK01002167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22435:16374"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67905.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          155 c          126 g          106 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggtacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcaga ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct
      181 gggagcagct ccaacatcgg aagaaatagt gtatcctggt accagcagct cccaggaaca
      241 gctcccaaac tcctcatcta ttatagtgat caacgagcct caggtgtctc tgaccgattc
      301 tctggctcca agtctggcac gtcagcctcc ctggccatca gcgggctcca ggccgaggat
      361 gaggctgatt attactgcgc agcatgggat gatagcctga gcggttacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002168             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:9901:14710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002168
VERSION     KCWK01002168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9901:14710"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67906.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          144 c          141 g           92 t
ORIGIN      
        1 acatgggggg gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccag cgcacgcccc tgtgctggtc
      241 atctatgcta atagcgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg ggggtgaggc tgactattac
      361 tgtcaggtgt gggacatgcg tagtgatcaa ccgctattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002169             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:13329:14456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002169
VERSION     KCWK01002169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13329:14456"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67907.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          146 c          129 g           99 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 tcaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaataccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002170             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:28178:8594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002170
VERSION     KCWK01002170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:28178:8594"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..404
                     /note="immunoglobulin light chain variable region"
     V_region        101..404
     V_segment       101..367
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <329..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67908.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       371..404
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>442
                     /gene="IGLC"
BASE COUNT           86 a          131 c          130 g           95 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcaggc
      121 accctcgatt tcagtgtccc ccggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 gtatgctgat agcgagcgat tctctggctc caaatcaggg aacacggcca ccctgaccat
      301 cagcggggtc gaggccgggg atgaggctga ctattactgt caggtgtggg acatgaatag
      361 tcatcatcta ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc
      421 cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002171             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11105:14702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002171
VERSION     KCWK01002171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11105:14702"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67909.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          157 c          123 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002172             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:9364:14430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002172
VERSION     KCWK01002172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:9364:14430"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67910.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          163 c          124 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagtagtgac
      181 ctcagtgttg gtagtaaaaa catctactgg taccagctga agccagggag cgctcccagg
      241 tcattcctgt actactactc cgactcagac aagcagcggg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtctatgaca gtagtgctaa tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01002173             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:18849:17621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002173
VERSION     KCWK01002173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18849:17621"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67911.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           87 a          157 c          125 g          111 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggtacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcagc ctccctcagc gtctgaggcc gccaggaaga gtgtctccat ctcctgttct
      181 ggaagcagct ccaacatcgg aagtcatagt gtctcctggt accagcaact cccaggaaca
      241 gctcccaaac tcctcatcta ttatagtgct caacgagcct caggtgtctc tgaccgattc
      301 tctggctctc agtctggcac gtcagcctcc ctggccatca gtgggctcca ggccgaggat
      361 gaggctgatt attactgcgc agcatgggat gatagtctga gcggttacat cttcggtgct
      421 gggacccggc tcgccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002174             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:19229:7907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002174
VERSION     KCWK01002174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19229:7907"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..393
                     /note="immunoglobulin light chain variable region"
     V_region        63..393
     V_segment       63..358
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <321..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67912.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       359..393
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>431
                     /gene="IGLC"
BASE COUNT           81 a          142 c          109 g           99 t
ORIGIN      
        1 acatgggggt ctgggctctg ctcctcctca ccctcctcac tcagggcaca ggatcctggg
       61 ctcaggctgc cccgactcag actccctctg tggccgggtc tcctggacag tcggtcacca
      121 tctcctgcac tggaaccagc agtgatattg ggtattatca tgctgtgtct tggtaccaac
      181 atcatccagg caaagccccc aaactcatga tttatgaggt caataaacgg cccgcagggg
      241 tctctgatcg cttctctggc tccaagtccg gcaacacggc ctccctgacc atctctgggc
      301 tccagactga ggatgaggct gattattact gcagctcata tgcaggcagc aacactttgt
      361 tcttcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      421 ctctcttccc g
//
LOCUS       KCWK01002175             371 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16770:5550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002175
VERSION     KCWK01002175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 371)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16770:5550"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..332
                     /note="immunoglobulin light chain variable region"
     V_region        126..332
     V_segment       126..296
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <261..>305
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67913.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       297..332
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        333..>371
                     /gene="IGLC"
BASE COUNT           69 a          121 c           98 g           83 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctcata ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg ccagtcccct gtgttgatca tcgatgagga caccaaacgg ccctctggga
      181 tccctgagag attctctggc tccagctcag ggacagtggc caccttgact atcagtgggg
      241 cccaggtgga ggatgaagct gactactact gttactcagc agacagcagt ggttatggct
      301 tattcggagg agggacccgg ctgaccgtcc tacgtcagcc caaggctgcc ccctcggtca
      361 ctctcttccc g
//
LOCUS       KCWK01002176             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:12655:19211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002176
VERSION     KCWK01002176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12655:19211"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..441
                     /note="immunoglobulin light chain variable region"
     V_region        111..441
     V_segment       111..402
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67914.1"
                     /translation="DYYCSAWDSSLTGGLF"
     J_segment       404..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          153 c          124 g          108 t
ORIGIN      
        1 atggggagct tcagctgtgg ctagagaaga caggactcag gacaatctcc agcatggcct
       61 gcttccctct catcctcacc gtcctcactc actgtgcagg atcctgggcc cagtctgtgc
      121 tgactcaacc accctcagcg tctggggccc ccgggcagag tgtcaccatc tcctgttctg
      181 gaagcagctc caacatcgga agtaattttg tatactggta ccagcagttc tcagggaagg
      241 cccccaaact cctcatccat aataataatc agcgatcctc aggggtccct gatcgattct
      301 ctggctccaa gtctggcacg tcagcctccc tggccatcag tgggctccgg tccgaggatg
      361 aggctgatta ttactgctca gcatgggata gcagtctgac cggtggctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002177             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:11114:18853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002177
VERSION     KCWK01002177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:11114:18853"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67915.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       411..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          156 c          129 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtatcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat cttttataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtcc ggtattcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccctctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002178             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:27620:13211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002178
VERSION     KCWK01002178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:27620:13211"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..386
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67916.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       387..418
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>456
                     /gene="IGLC"
BASE COUNT           90 a          141 c          126 g           99 t
ORIGIN      
        1 acatgggggg gctcagaagc agagctctgg ggtgtctcca ccatggcctg gactcctctc
       61 tggctcaccc tcctcagtct ttgcacaggt tctatggttt cttctgagct gactcaggac
      121 cctgcagtgt ctgtggcctt gggacagaca gtcaggatta cctgccaagg agacagcctc
      181 agaagctctt atgcaagctg gtaccaacag aggccaggcc aggcccctgt gctggtcgtc
      241 tatggtaaca actaccggcc ctcagggatc ccagagcgat tctctggctc ctactcacga
      301 aacacagctt ccttgaccat ctctggggct caggtggaag atgaggctga ctattactgt
      361 gactcctggg acagcagcgg aacccaattc ggaggaggga cccggctgac cgtcctaggt
      421 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002179             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:6858:15600
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002179
VERSION     KCWK01002179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:6858:15600"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67917.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       408..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          156 c          115 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatatac tggtaccacc agaagccagg gagtcccccc cggtatcttc
      241 tgaggttcaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcaacg aacacaggga ttttacgcat ctctagactc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tgattatatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002180             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:6633:9375
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002180
VERSION     KCWK01002180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:6633:9375"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67918.1"
                     /translation="DYYCCSYAGSDTFVLF"
     J_segment       404..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           84 a          163 c          123 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caacaacatc cagccacagc
      241 ccccaaactc gtgatttttg aggtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct ggcctccagc ctgacgacga
      361 ggctgattat tactgctgct catatgcagg cagcgacact ttcgtgttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002181             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22885:13290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002181
VERSION     KCWK01002181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22885:13290"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..424
                     /note="immunoglobulin light chain variable region"
     V_region        101..424
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67919.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          128 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacacaagtc ttgatcacgg cttatttgga ggagggaccc ggctgaccgt
      421 cctaagtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002182             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:4352:5309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002182
VERSION     KCWK01002182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4352:5309"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67920.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          163 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtacca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002183             361 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:8419:15165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002183
VERSION     KCWK01002183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 361)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:8419:15165"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..323
                     /note="immunoglobulin light chain variable region"
     V_region        12..323
     V_segment       12..287
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <251..>295
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67921.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       291..323
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        324..>361
                     /gene="IGLC"
BASE COUNT           80 a          105 c          106 g           70 t
ORIGIN      
        1 acatggggaa ttgactcagt caccctcagt gtcagcggcc tcaggacagc cggccaggat
       61 cacctgtggg ggagacaaca ttggaactaa aactgtgcac tggtaccaac agaagccacc
      121 gcagggccct gtattggtca tctttgctga tagtagacgg ccctcaggga tccctgagcg
      181 attctctggc tccaactcag ggaacaccgc caccctgacc atcagcaggg tcgaggccgg
      241 ggatgaggct gactattact gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg
      301 ggggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      361 g
//
LOCUS       KCWK01002184             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:15385:16340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002184
VERSION     KCWK01002184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:15385:16340"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67922.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          143 c          133 g           95 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gaactgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaat taaaactgta cactggtacc agcagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgatagtaag cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002185             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:8662:5292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002185
VERSION     KCWK01002185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8662:5292"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67923.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          136 c          123 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 ggcaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002186             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:22408:2817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002186
VERSION     KCWK01002186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22408:2817"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..433
                     /note="immunoglobulin light chain variable region"
     V_region        85..433
     V_segment       85..396
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67924.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       399..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           88 a          158 c          119 g          106 t
ORIGIN      
        1 acatggggag aggtagccgt gtccaccatg gccctgactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctcccagcct gtgttgactc agccaccctc cctgtctgca
      121 tccccgggag catcggccag actcccctgc accctgagca gtgacctcag tgttggtggt
      181 acaaacatgt actggtacca gcagaagcca gggcgcgctc ccaggttttt cctgtactac
      241 aactccgact cagacaagca ggtgggacct ggggtcccca atcgagtctc tggctccaag
      301 gagacctcaa gaaacacagc gtttttgctc atctctgggc tccagcctga ggacgaggcc
      361 gattattact gtcaggtgta tgacagtagt gctaatgtct tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002187             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:24052:10932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002187
VERSION     KCWK01002187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24052:10932"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67925.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       400..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          156 c          120 g          107 t
ORIGIN      
        1 acatgggggg gatctcacga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtggccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtcc ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacactttg ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002188             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:13325:12063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002188
VERSION     KCWK01002188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13325:12063"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..446
                     /note="immunoglobulin light chain variable region"
     V_region        98..446
     V_segment       98..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67926.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          163 c          121 g          111 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gtagtgacct
      181 cagtgttggt agtaaaaaca tctactggta ccagctgaag ccagggagcg ctcccaggtc
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt ctatgacagt agtgctaatg tgttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01002189             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:12280:8015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002189
VERSION     KCWK01002189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12280:8015"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..303
                     /note="immunoglobulin light chain variable region"
     V_region        8..303
     V_segment       8..264
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67927.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       266..303
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           70 a          103 c           91 g           77 t
ORIGIN      
        1 acatgggggc cagactcccc tgcaccctga gcagtgacct cagtgttggt agtaaaaaca
       61 tgtactggta ccagcagaag ccagggagcg ctcccaggtt attcctgtac tactactccg
      121 actcagacaa ccagctggga cctggggtcc ccaatcgagt ctctggctcc aaggagacct
      181 caagtaacac agcgtttttg ctcatctctg ggctccagcc tgaggacgag gccgattatt
      241 tctgccaggt gtttgacagt agtgttgtgt tcttcggagg agggacccga ctgaccgtcc
      301 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002190             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:6645:16004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002190
VERSION     KCWK01002190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6645:16004"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67928.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          153 c          119 g          114 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcgtca gccagtctca cttgcacctt cagtggtggc atcaatgttg
      181 ctggctacca catacactgg taccagcaga agccagggag tcctccccgg tttcttctga
      241 gatacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcatcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gtagtggtga ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002191             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:20392:5004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002191
VERSION     KCWK01002191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20392:5004"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67929.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       401..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>476
                     /gene="IGLC"
BASE COUNT           93 a          155 c          117 g          111 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgactacca cgtacactgg tatcagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggcctgg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaat acagggattt tacacatctc tggtttccag tctgaggatg
      361 aggctgacta ttactgtgcc attggccacg gcagcggtga ttacatcttc ggtactggga
      421 cccggctcac cgtccaaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002192             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:22531:18218
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002192
VERSION     KCWK01002192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22531:18218"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..403
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67930.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       408..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           92 a          160 c          114 g          114 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagtcaga ctcagctgca ccttgagcag tggcatcaat
      181 gttggttctt acaccatatt ctggtaccag cagaagccag ggagtcctcc ccggttcctt
      241 ctgtactact actcagactc aaataatcac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc caatgcaggg cttttactga tctctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccatgtgg cacagcagcg cttatgcctt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002193             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:7216:12248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002193
VERSION     KCWK01002193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7216:12248"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67931.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       413..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           90 a          155 c          130 g          113 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag gttattatgt gcagtggtac cagcagcttc
      241 cagggacggc ccccaaactc ctcatctatg aaaatgataa acgaccctca ggggtttctg
      301 atcgattctc tggctcccag tctgattcct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagcttgagt gttgtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01002194             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:10843:10140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002194
VERSION     KCWK01002194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:10843:10140"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67932.1"
                     /translation="DYYCQSYDSNLSAMLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          149 c          121 g          109 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag tagttccaac
      181 ttcggggcgg gttattatgt gcactggtac cagcaacttc caggaacggc ccccaaactc
      241 ctcatctatg aaaacaatat gcgaccctca ggggtttctg atcgattctc tggctccaag
      301 tctggtacct cagcctccct gaccatcact ggactccagt ctgaggatga ggctgattat
      361 tactgccagt cctatgacag taatttgagt gctatgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002195             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:8459:8631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002195
VERSION     KCWK01002195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:8459:8631"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..439
                     /note="immunoglobulin light chain variable region"
     V_region        113..439
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67933.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>481
                     /gene="IGLC"
BASE COUNT           88 a          155 c          126 g          112 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctct cagtctggca cgtcagcctc cctggccatc agttggctcc aggccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagtctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcgccgtcg taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01002196             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:28786:10109
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002196
VERSION     KCWK01002196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:28786:10109"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67934.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           89 a          162 c          120 g          108 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcgtcaatg
      181 tgggtagtta cagcgtattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacca gtcagactca aggaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaacga tgcttcagcc aatgcagggc tgttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccctatggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002197             383 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:7659:19814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002197
VERSION     KCWK01002197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 383)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 383)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7659:19814"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..345
                     /note="immunoglobulin light chain variable region"
     V_region        3..345
     V_segment       3..305
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <273..>317
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67935.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       308..345
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        346..>383
                     /gene="IGLC"
BASE COUNT           80 a          125 c           94 g           84 t
ORIGIN      
        1 acatggggac tcagccggcc tccctctctg catctcctgg agcatcagcc agtctcacat
       61 gcaccttcag cggtggcatc aatgttgctg cctaccacat acactggtac cagcagaagc
      121 cagggagtcc tccccggtat cttctgagat acaaatcaga ctcagataag gaccagggct
      181 ctggagtccc cagccgcttc tctggatcca aagatgcctc agcgaacaca gggattttac
      241 gcatctctgg gctccagtct gaggatgagg ctgactacta ctgtgccatt gggcacagca
      301 gcggtgatta cattttcgct gctgggaccc gcctcaccgt cctaggtcag cccaaggctt
      361 cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002198             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:21191:8449
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002198
VERSION     KCWK01002198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21191:8449"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67936.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          148 c          129 g           97 t
ORIGIN      
        1 acatgggctg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gttctggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg aatctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaagt cttgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002199             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:18714:5172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002199
VERSION     KCWK01002199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18714:5172"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67937.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           92 a          145 c          133 g           94 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctcttc gacctcctat gaactgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc agcagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgacagtaaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002200             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:22535:8322
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002200
VERSION     KCWK01002200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22535:8322"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67938.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           89 a          163 c          119 g          110 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgccct
      181 cagtgttggt aataaaaaca tgtactggta ccaacagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caactaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtttgacagt agtgctgtgt tattcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01002201             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:3194:16159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002201
VERSION     KCWK01002201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:3194:16159"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67939.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          161 c          113 g          109 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggggggggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002202             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:19551:9412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002202
VERSION     KCWK01002202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19551:9412"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..255
                     /note="immunoglobulin light chain variable region"
     V_region        10..255
     V_segment       10..218
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <180..>227
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67940.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       221..255
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        256..>293
                     /gene="IGLC"
BASE COUNT           58 a           89 c           84 g           62 t
ORIGIN      
        1 acatgggcat tggaactaaa tatgtgcact ggtaccagca gaagccagcg caggcccctg
       61 tgttggtcat ctatgctgat accagacggc cctcagggat ccctgagcga ttctctggct
      121 ccaactcagg gaacaccgcc accctgacca tcaccggggt cgaggccggg tatgaggctg
      181 actatttctg tcaggtttgg gacgatagta gtgatcatcc ggtattcggc ggagggaccc
      241 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002203             415 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:28698:13192
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002203
VERSION     KCWK01002203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 415)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:28698:13192"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    29..377
                     /note="immunoglobulin light chain variable region"
     V_region        29..377
     V_segment       29..337
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>349
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67941.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       341..377
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>415
                     /gene="IGLC"
BASE COUNT           84 a          134 c          102 g           95 t
ORIGIN      
        1 acatgggcac tgcacaggtt ccctctccaa gcctatgctg actcagccgg cctccctctc
       61 agcatctcct ggagcatcag ccagtctcac atgcaccttc agcggtggca tcaatgttgc
      121 tgactaccac gtacactggt atcagcggaa gccagggagt cccccccggt atcttctgag
      181 gtacaaatca gactcagata agggcctggg ctctggagtc cccagccgct tctctggatc
      241 caaagatgct tcagcgaata cagggatttt acacatctct ggtttccagt ctgaggacga
      301 ggctgactat tactgtgcca ttggccacgg tagcggtgac tacatcttcg gtactgggac
      361 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002204             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:9510:15442
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002204
VERSION     KCWK01002204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9510:15442"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67942.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       396..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>435
                     /gene="IGLC"
BASE COUNT           84 a          124 c          132 g           95 t
ORIGIN      
        1 acatggggga gcctgacttt gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgctcacttt acaggctctg tggcctccta tgagttgcct
      121 cagccacgct cagtgtccgt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aacattggaa gtaatagtgt gcattggtac cagcagaagc caccgcgggc ccctgtattg
      241 gtcatctctg ttgatagcga acggccctca gggatccctg agcgattctc tggttccaga
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggataa tatttataaa tacgcggtat tcggcggagg gacccggctg
      421 accgtcctag gtcag
//
LOCUS       KCWK01002205             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:23136:8377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002205
VERSION     KCWK01002205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:23136:8377"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67943.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          155 c          126 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gcgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gttccaacat cggaagtcat agtgtatcct ggtatcagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002206             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:24055:17824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002206
VERSION     KCWK01002206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24055:17824"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..439
                     /note="immunoglobulin light chain variable region"
     V_region        94..439
     V_segment       94..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67944.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       403..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           92 a          164 c          109 g          112 t
ORIGIN      
        1 acatggggca ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggaac atcagccaga ctcagctgca ccttgagcag tggcaatgtt
      181 ggcagttaca gcatattctg gtaccagcag aagccaggga gtcctccccg gttccttctt
      241 tactactact cagactcaag taaccaccag gactctggag tccccagccg cttctctgga
      301 tcgaaagatg cttcagccaa tgcagggctt ttactgatct ctgggctcca gtctgatgat
      361 gaggctgact attactgtgc cacatggcac agcagcgctt cttacatctt cggtcctggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01002207             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:13654:10074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002207
VERSION     KCWK01002207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13654:10074"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..254
                     /note="immunoglobulin light chain variable region"
     V_region        8..254
     V_segment       8..217
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67945.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       218..254
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           59 a           87 c           77 g           69 t
ORIGIN      
        1 acatgggatc ggaagtcata gtgtatcctg gtaccagcag tttccaggaa cagctcccaa
       61 actcctcatc tattatgatg atcaacgagc ctcgggtgtc tctgaccgat tctctggctc
      121 caggtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg atgaggctga
      181 ttattactgc gcagcatggg atgatagcct gagaggttac atcttcggtg atgggacccg
      241 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002208             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:20390:15948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002208
VERSION     KCWK01002208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20390:15948"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67946.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>460
                     /gene="IGLC"
BASE COUNT           94 a          143 c          124 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaagatc acctgctctg gagatgcact
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 cgatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002209             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:29434:11360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002209
VERSION     KCWK01002209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:29434:11360"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67947.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggtgtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002210             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:9878:13299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002210
VERSION     KCWK01002210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:9878:13299"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67948.1"
                     /translation="DYYCCSYRSENTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          155 c          123 g          109 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgta ttggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag caacactcag agacagcccc
      241 cacactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattac tgttgttcat ataggagtga aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002211             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:6485:19529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002211
VERSION     KCWK01002211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6485:19529"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67949.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          157 c          120 g          108 t
ORIGIN      
        1 acagggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcacc tccaacatcg gaagcaataa tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctctttt attataatga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctcttgctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgataacctg agcggctaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01002212             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:17762:6829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002212
VERSION     KCWK01002212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:17762:6829"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67950.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       411..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           91 a          162 c          124 g          107 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctcgtct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
      121 tgtgctgaca cagccgccct cagtgtctgg ggccccaggg cagagggtca ccatctcctg
      181 cactgggagc agctccaaca ttggaggtta ttatatatcc tggtaccagc agctcccagg
      241 aacggccccc aaactcctcg tctatgacaa taataagcga ccctcagggg tttctgaccg
      301 attctctggc tccaagtctg gttcctcagc caccctgacc atcactgggc tccagactga
      361 ggatgaggct gattattact gccagtccta tgacagcagt ctgagtgctc gggtattcgg
      421 cggagggacc cggctaaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01002213             398 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:23647:3376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002213
VERSION     KCWK01002213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 398)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:23647:3376"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    30..360
                     /note="immunoglobulin light chain variable region"
     V_region        30..360
     V_segment       30..323
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <285..>332
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67951.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       326..360
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        361..>398
                     /gene="IGLC"
BASE COUNT           72 a          126 c          108 g           92 t
ORIGIN      
        1 acatgggtca ctgtgcaggg tcctgggccc agtctgtgct gactcagcca ccctcagcgt
       61 ctggggctcc cgggcagagt gtcaccatct cttgttctgg aagcatctcc agcattggaa
      121 gtagtgatgt atgttggtac cagcaactcc caggaacggc ccccaaactc ctcatcaatt
      181 atagtgatca gcgactctca ggggtccctg accgattctc tggctctaag tctggcacct
      241 cagcctccct ggccatcact ggtctccgat ctgaggatga ggctgattat tactgtgcag
      301 cctgggatag cagcctgagc agtccggtat tcggcggagg gacccggctg accgtcctag
      361 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002214             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:14229:16621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002214
VERSION     KCWK01002214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14229:16621"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67952.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          158 c          123 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgcccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002215             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:24334:5226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002215
VERSION     KCWK01002215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24334:5226"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67953.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          156 c          121 g          110 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggaac atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgttggct accacataca ctggtaccag cagaagccag ggagtcctcc ccggtatctt
      241 ctgagataca aatcggactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc gaacgcaggg attttacgca tctctgggct ccagtctgag
      361 gatgaggctg actattactg tgccattggg cacagcagcg gtgattacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002216             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:9751:7984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002216
VERSION     KCWK01002216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:9751:7984"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67954.1"
                     /translation="DYYCSSYAGSNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          156 c          117 g          112 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtaat attggatatt atcatgctgt ttcttggtac caacaccgtc caggcaaagc
      241 ccccaaactc atgatttatg acgtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctgacaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacaat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002217             373 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:19407:18370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002217
VERSION     KCWK01002217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 373)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19407:18370"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    131..335
                     /note="immunoglobulin light chain variable region"
     V_region        131..335
     V_segment       131..298
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <260..>307
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67955.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       300..335
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        336..>373
                     /gene="IGLC"
BASE COUNT           67 a          126 c           94 g           86 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctcgtc tcctctcctc ctcacccttt tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac acggccccca aactcctcgt ctatgacaat aataagcgac cctcaggggt
      181 ttctgaccga ttctctggct ccaagtctgg ttcctcagcc accctgacca tcactgggct
      241 ccagactgag gatgaggctg attattactg ccagtcctat gacagcagtc tgagtgctcg
      301 ggtattcggc ggagggaccc ggctaaccgt cctaggtcag cccaaggctg ccccctcggt
      361 cactctcttc ccg
//
LOCUS       KCWK01002218             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:27263:13360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002218
VERSION     KCWK01002218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:27263:13360"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..451
                     /note="immunoglobulin light chain variable region"
     V_region        121..451
     V_segment       121..414
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67956.1"
                     /translation="DYYCQAYDSSLIAVLF"
     J_segment       415..451
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT           93 a          157 c          125 g          114 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc actcacttca cagttccagg gtcctgggcc
      121 cagtctgtgc tgacgcagcc gccctcagtg tctggggcgc ccgggcagag ggtcaccatc
      181 tcctgcactg ggagcagctc caacattgga gattattttg tgcagtggta ccagcacctt
      241 ccaggaacgg cccccaaact cctcatctat gaaaataata agcgaccctc agggatttct
      301 gatcgaatct ctggctccca gtctggaacc tcagcctccc tgaccatcac tggactccag
      361 tctgaggatg aggctgatta ttactgccag gcctatgata gcagtttgat tgctgtgtta
      421 ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCWK01002219             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:4805:9216
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002219
VERSION     KCWK01002219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4805:9216"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67957.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           81 a          165 c          114 g          115 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 caccagtgac gttggtggtt ctaactctgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaactc atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagt ctgaggacga
      361 ggctgattat tactgttgtt cacattcaac cagtagcact tacgtcttcg gtcctgggac
      421 ccggctctcc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002220             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:21762:18206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002220
VERSION     KCWK01002220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21762:18206"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67958.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          157 c          118 g          111 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctgact accacataca ctggtaccag cataagtcag ggagtcctcc ccggtatctt
      241 ctaagataca aatcagactc agatcagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc gaacacgggg attttacacg tctctgggct ccagtctgag
      361 gatgaggctg actattactg tgccattggg cacagcagcg gtgattacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002221             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:11526:15136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002221
VERSION     KCWK01002221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11526:15136"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67959.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          162 c          120 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcaatatcg gtaataaaaa catgtactgg taccagcaga agccagggag cgctcccaag
      241 ttattcctgt actactactc cgactcagac atgcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtcat acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctgt attattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002222             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:14752:22286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002222
VERSION     KCWK01002222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14752:22286"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67960.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          157 c          121 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagtctgg gagtcctccc cggtatcttc
      241 taagatacaa atcagactcg gatcagggcc agggctctgg ggtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacgggga ttttacacgt ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002223             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:21622:9330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002223
VERSION     KCWK01002223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21622:9330"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..277
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67961.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       278..314
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           77 a          113 c           85 g           77 t
ORIGIN      
        1 acatggggga gcatcagcca gtctcacatg caccttcagc ggtggcatca atgttgctgc
       61 ctaccacata cactggtacc agcagaagcc agggagtccc ccccggtatc ttctgactta
      121 caaaccagac tcagataagg gccagggctc tggagtcccc agccgcttct ctggatccaa
      181 aaatgcttca acgaacacag gcattttaca catctctggg ctccagtctg aggatgaggc
      241 tgactatttc tgtgccattg gacacagcag cggtccttac atcttcggtg ctgggacccg
      301 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002224             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:22009:15698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002224
VERSION     KCWK01002224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22009:15698"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67962.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       402..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          150 c          123 g          113 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggttcaggct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatgt tgggtattat aacgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 ccaaactcat gatttatgac gtcattaagc ggccctcagg ggtttctgat cgcttctctg
      301 gctccaagtc tggcgacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gaaataattt tttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002225             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:25287:12990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002225
VERSION     KCWK01002225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:25287:12990"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67963.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          161 c          111 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt tagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaggatgc ttcggccaat gcaggccttt tagtgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002226             397 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20555:8879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002226
VERSION     KCWK01002226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 397)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20555:8879"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..359
                     /note="immunoglobulin light chain variable region"
     V_region        14..359
     V_segment       14..323
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <290..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67964.1"
                     /translation="DYYCAVWSSSAYIF"
     J_segment       324..359
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>397
                     /gene="IGLC"
BASE COUNT           72 a          127 c           99 g           99 t
ORIGIN      
        1 acatgggctg tcacagcctg tgctgactca gccggcctcc ctctcagcat ctcctggagc
       61 atcagtcaga ctcacctgca ccttgcgcac tggcctcaat gttggtggct actacatatt
      121 ctggtaccag cagaagccag ggagtcctcc ccggttcctt ctgaattact actcagactc
      181 aaatcagggc cagggctctg gagtccccag ccgcttctct ggatccaaag atgtttcagc
      241 caatgcaggg cttttactga tctctgggct ccagtctgag gatgaggctg actattactg
      301 tgccgtttgg tccagcagcg cttacatctt cggtggtggg actcggctca ccgtcctagg
      361 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01002227             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:17623:21574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002227
VERSION     KCWK01002227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17623:21574"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67965.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          162 c          118 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatattgg caataaaaac atgtactggt accagcagaa gccagggagc gctcccaagt
      241 tattcctgta ctactactcc gactcagaca tgcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gaggaacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002228             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:22915:10182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002228
VERSION     KCWK01002228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22915:10182"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..269
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67966.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       270..306
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           74 a          103 c           90 g           77 t
ORIGIN      
        1 acatgggggc cagactcccc tgcaccctga gcagtgacct cagtgttggt ggtaaaaaca
       61 tgtactggta ccagcagaag ccagggcgcg ctcccaggtt tttcctgtac tacaactccg
      121 actcagacaa gcagctggga cctggggtcc ccaatcgagt ctctggctcc aaggagacct
      181 caagtaacac agcgtttttg ctcatctctg ggctccagcc tgaggacgag gccgattatt
      241 actgtcacgt atatgacagt agtactaatg tgttattcgg aggagggacc cgtctgaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002229             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:18620:14005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002229
VERSION     KCWK01002229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18620:14005"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67967.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           85 a          151 c          137 g           92 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga cctggctcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta actatgtgca ctggtaccag cagaagccag cgcaggcccc tgtcgagatc
      241 atctttgctg ataacaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggatcaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactatttc
      361 tgtcaggtgt ggggcagtcg tagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002230             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:13626:7298
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002230
VERSION     KCWK01002230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13626:7298"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67968.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          161 c          125 g          109 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 tcatttctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tggactccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgcgaa tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01002231             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:7678:5220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002231
VERSION     KCWK01002231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7678:5220"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67969.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          155 c          126 g          108 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa cagtgtcgcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtatcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatgatg atcaacgaac ctcgggtgtc tctgaccgat
      301 tctctggctc caggtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagaggttac atcttcggtg
      421 atgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01002232             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12699:6428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002232
VERSION     KCWK01002232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12699:6428"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..441
                     /note="immunoglobulin light chain variable region"
     V_region        94..441
     V_segment       94..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67970.1"
                     /translation="DYFCAIGHSSGNYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          154 c          123 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccgagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgtac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatatac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacag atcagagtca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattgggc acagcagcgg taattacatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002233             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:19286:15972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002233
VERSION     KCWK01002233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19286:15972"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67971.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           98 a          142 c          130 g           92 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga gctgactcag
      121 gcaccctcag tgtcagcggc ctcaggacag acggccagga tcacctgtgg cggagacaac
      181 attggaatta aaaatgtcca ctggtaccag cagaagccag cacaggcccc tgtggtagtc
      241 atctatgctg ataacaaacg gccctcaggg atccctgagc gactctctgg ctccaactca
      301 gggaatattt ccaccctgac catcagcagg gtcgaggccg gggatgaggc agactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg gtattcggcg gagggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002234             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:17913:19039
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002234
VERSION     KCWK01002234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:17913:19039"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..380
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67972.1"
                     /translation="AYYCQVWDSDTDHYIF"
     J_segment       392..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          151 c          130 g           95 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gacctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaac taattttgtg cactggtacc agcagaagcc agcgcaggcc cctatgcagg
      241 tcatctatgc tgatagcaaa cggccctcag ggatccctga gagattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gagtcgaggc cggggatgag gctgcctatt
      361 actgtcaggt gtgggacagt gatactgatc attacatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01002235             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:18536:7569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002235
VERSION     KCWK01002235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:18536:7569"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <348..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67973.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       393..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           92 a          148 c          132 g           95 t
ORIGIN      
        1 acatgggggg cttcagaagc agcatctggg acatgtcagc catggcctgg acgcctctcc
       61 tcctcagcct cctcgctcac tgcacaggct ctgtggcctc ctatgagctg actcagccac
      121 cctcagtgtc ggtgtcccca ggacagacag ccagcatcac ctgctctgga aataaattgg
      181 ggaatgtata tgcttactgg ttccagcaga agccaggcca ggcccctgta gtggtcatct
      241 acaaagatac caaccggccc tcagggatcc ctgagcgatt ctctggctcc gactcaggga
      301 acacggccac cctgaccatc agcagggtcg aggctgggga tgaggccgac tatttttgtg
      361 ctgcagccta tggcagtggc agcagctggc agtgggtatt cggcggaggg acccggctaa
      421 tcgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002236             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:18176:6180
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002236
VERSION     KCWK01002236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18176:6180"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67974.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          143 c          132 g           96 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gaattgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc aacagaagcc accgcagggc cctctattgg
      241 tcatctttgc tgatagtaga cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gtcccctcgg tcactctctt cccg
//
LOCUS       KCWK01002237             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:18631:7760
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002237
VERSION     KCWK01002237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18631:7760"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67975.1"
                     /translation="DYYCQSADSSGNHPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          106 a          132 c          123 g          102 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tcttcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatgctcagt ggttccagca gaagccaggc caggcccctg tgttggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgaacga ttctctagtt ccagttcagg
      301 gacaacagtt accttgacca tcagtggggc ccaggtagaa gatgaggctg actattactg
      361 tcaatcagca gacagcagtg gtaatcatcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002238             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:21453:4624
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002238
VERSION     KCWK01002238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21453:4624"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67976.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           91 a          143 c          124 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctaccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002239             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:13438:16387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002239
VERSION     KCWK01002239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13438:16387"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..334
                     /note="immunoglobulin light chain variable region"
     V_region        8..334
     V_segment       8..299
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67977.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       300..334
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        335..>374
                     /gene="IGLC"
BASE COUNT           77 a          118 c           88 g           91 t
ORIGIN      
        1 acatgggaac ctccctctca gcatctccgg gagcatcagc cagactcagc tgcaccttta
       61 gcagtggcat caatgttggt agttacagca tattctggta ccagcagaag ccagggagtc
      121 ctccccggta ccttctctac tactactcag actcaagtaa acaccagggc tctggagtcc
      181 ccagccgctt ctctggatcc aaagatgctt cggccaatgc aggcctttta ctgatctctg
      241 gggtccagtc tgaagatgag gctgactatt actgtgccat atggcacagt agcgcttctt
      301 acttcttcgg tactgggacc cggctcaccg tcctgggtca gcccaaggct tcccccacgg
      361 tcactctgtt cccg
//
LOCUS       KCWK01002240             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:9647:18679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002240
VERSION     KCWK01002240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9647:18679"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67978.1"
                     /translation="VYYCQVWDSSSDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          151 c          129 g           96 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaagccac cgcaggcccc tgtgcaggtc
      241 atctattctg ataccaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgtctattac
      361 tgtcaggtgt gggacagtag tagtgatcat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002241             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:17932:22119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002241
VERSION     KCWK01002241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17932:22119"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67979.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           81 a          157 c          129 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcagcact cagggacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg gtcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tattgttgct catataggag tggaaacact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002242             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:14834:5143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002242
VERSION     KCWK01002242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14834:5143"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..278
                     /note="immunoglobulin light chain variable region"
     V_region        8..278
     V_segment       8..241
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <206..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67980.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       245..278
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>316
                     /gene="IGLC"
BASE COUNT           68 a           92 c           81 g           75 t
ORIGIN      
        1 acatggggac ctcagtgttg gtggtaaaaa catttactgg taccagcaga agccagggcg
       61 cgctcccagg tttttcctgt actacaactc cgactcagac aagcagctgg gacctggggt
      121 ccccaatcgc gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc
      181 tgggctccag cctgaggacg aggccgatta ttactgtcac gtatatgaca gtagtactaa
      241 tgttttattc ggaggaggga cccgtctgac cgtcctaggt cagcccaagg ctgccccctc
      301 ggtcactctc ttcccg
//
LOCUS       KCWK01002243             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:14646:9015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002243
VERSION     KCWK01002243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14646:9015"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..312
                     /note="immunoglobulin light chain variable region"
     V_region        8..312
     V_segment       8..275
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67981.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       276..312
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>350
                     /gene="IGLC"
BASE COUNT           76 a          102 c           95 g           77 t
ORIGIN      
        1 acatgggggg agcatcggcc agactcccct gcaccctgag cagtgacctc agtgttggaa
       61 ataaaaacat atactggtac cagcagaagc cagggagcgc tcccaggtta ttcctgtact
      121 actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc tctggctcca
      181 aggagacctc aagtcataca gcgtttttgc tcatttctgg gctccagcct gaggacgagg
      241 ccgattatta ctgtcaggtg tatgacgata gtgctgtgtt attcggagga gggacccggc
      301 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002244             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:11383:8000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002244
VERSION     KCWK01002244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11383:8000"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67982.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          158 c          126 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcggcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002245             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:16426:5624
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002245
VERSION     KCWK01002245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:16426:5624"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..434
                     /note="immunoglobulin light chain variable region"
     V_region        88..434
     V_segment       88..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67983.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       400..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>474
                     /gene="IGLC"
BASE COUNT           92 a          160 c          108 g          114 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttta acagtggcat caatgttggt
      181 agttacagca tattctggta ccagcagaag ccagggagtc ctccccggta ccttctctac
      241 tactactcag actcaattaa acaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cggccaatgc aggcctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccat atggcacagc agcgcttctt acttcttcgg tagtgggacc
      421 cggctcaccg tcctgggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01002246             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:10292:18135
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002246
VERSION     KCWK01002246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10292:18135"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67984.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          147 c          129 g           97 t
ORIGIN      
        1 acatgggggt gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tatactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002247             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:6054:9118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002247
VERSION     KCWK01002247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:6054:9118"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67985.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       409..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           88 a          155 c          128 g          110 t
ORIGIN      
        1 acatggggag cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtactca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag ccaccctcag cgtctggggc tcccgggcag agtgtcacca tctcttgttc
      181 tggaagcatc tccagcattg gaagtagtga tgtatgttgg taccagcaac tcccaggaac
      241 ggcccccaaa ctcctcatca attatagtga tcagcgactc tcaggggtcc ctgcccgatt
      301 ctctggctct aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga
      361 tgaggctgat tattactgtg cagcctggga tagcagcctg agcagtccgg tattcggcgg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01002248             411 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:10980:20502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002248
VERSION     KCWK01002248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 411)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10980:20502"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    25..373
                     /note="immunoglobulin light chain variable region"
     V_region        25..373
     V_segment       25..333
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <301..>345
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67986.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       336..373
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        374..>411
                     /gene="IGLC"
BASE COUNT           85 a          131 c          102 g           93 t
ORIGIN      
        1 acatggggca caggttccct ctccaagcct atgctgactc agccggcctc cctctcagca
       61 tctcctggaa catcagccag tctcacatgc accttcagcg gtggcatcaa tgttgttggc
      121 taccacatac actggtacca gcagaagcca gggagtcctc cccggtatct tctgagatac
      181 aaatcggact cagataaggg ccagggctct ggagtcccca gccgcttctc tggatccaaa
      241 gatgcttcat cgaacgcagg gattttacgc atctctggac tccagtctga ggatgaggct
      301 gactattact gtgccattgg gcacagcagc ggtgattaca tcttcggtgc tgggacccgg
      361 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01002249             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:9042:12759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002249
VERSION     KCWK01002249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:9042:12759"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..404
                     /note="immunoglobulin light chain variable region"
     V_region        80..404
     V_segment       80..367
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <329..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67987.1"
                     /translation="DYYCQSSHSRVNHPFF"
     J_segment       374..404
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>442
                     /gene="IGLC"
BASE COUNT           98 a          134 c          114 g           96 t
ORIGIN      
        1 acatgggtct gggtgtctca ccatgacctg gaccactgtt ctgctcccct ttctcactct
       61 ctgcacaggc tctgaggcct cctatgagct gacacagcca ccctcagtgt cagtgtcccc
      121 aggacagacg gccaggatca cctgctctgg agaaacactg gcaaaaaaat atgctcagtg
      181 gttccagcag aagccaggcc aggcccctgt gttggtgata tataaagaca gtgagaggcc
      241 ctcagggatc cctgagcgat tctctagctc cagttcaggg acaacagtta ccttgaccat
      301 cagtggggcc caggcagaag atgaggctga ctattactgt caatcatcgc acagcagggt
      361 taatcatccg tttttcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc
      421 cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002250             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:26824:10965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002250
VERSION     KCWK01002250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:26824:10965"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67988.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          150 c          135 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gcctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta agtatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
      241 atctatgctg ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 ggaaacaccg ccaccctgac catcagcggg gtcgaggccg ggtatgaggc tgactatttc
      361 tgtcaggtgt gggacgatag tagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002251             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:10669:14134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002251
VERSION     KCWK01002251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10669:14134"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67989.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           85 a          155 c          119 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag cagctcccag gcacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctctcagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagctt gggatgatag cctgagcggt tacatcttcg gtgctgggac ccggctcgcc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002252             376 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:23396:14101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002252
VERSION     KCWK01002252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 376)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23396:14101"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..338
                     /note="immunoglobulin light chain variable region"
     V_region        14..338
     V_segment       14..295
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <263..>310
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67990.1"
                     /translation="DYFCQVWDSISDHPLF"
     J_segment       304..338
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        339..>376
                     /gene="IGLC"
BASE COUNT           80 a          113 c          110 g           73 t
ORIGIN      
        1 acatggggcg acctcctatg agctgactca gccaccctcg gtgtcagcgg cctcaggaca
       61 gacggccagg atcacctgtg ggggagacaa cattggaact aaatatgtgc actggtacca
      121 gcagaagcca gcgcaggccc ctgtgcaggt catttatggt gataccaaac ggcactcagg
      181 gatccctgag cgattctctg gctccaactc agggaacacc gccaccctga ccatcagcgg
      241 ggtcgaggcc ggggatgagg ctgactattt ctgtcaggtg tgggacagta ttagtgatca
      301 tcccttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      361 ggtcactctc ttcccg
//
LOCUS       KCWK01002253             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:20547:12141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002253
VERSION     KCWK01002253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20547:12141"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67991.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           92 a          140 c          133 g          102 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtgga ggagacaaca
      181 ttggaagtga agttgtcaac tggtaccagc agaggccacc gcaggcccct atactggtca
      241 tctatgctga ttatgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagtggag tcgaggccgg ggatgaggct gactattatt
      361 gtcaggtgtg ggacatatat attgaccatc cggtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002254             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:13652:16054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002254
VERSION     KCWK01002254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13652:16054"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67992.1"
                     /translation="YYYCSSYAGSHTYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           78 a          164 c          121 g          112 t
ORIGIN      
        1 acatgggggc tggggtctca gggggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacagggtcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt cttctggttc cagcagcacc ccggcaaagc
      241 ccccaaactc atgatttatg atgtcactca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctggctaca cggcctccct gaccatctct gggctccagg ctgcggatga
      361 ggcttattat tactgcagct catatgcggg cagccacact tacatcttcg gtactgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002255             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:7076:18081
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002255
VERSION     KCWK01002255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7076:18081"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67993.1"
                     /translation="DYYCSSYAGRNSFLF"
     J_segment       400..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          155 c          125 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctgggaccag
      181 cagtgatgtt gggtattctc atgccgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 caaactcatg atttatgatg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg gtccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag gaactctttc ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002256             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:20354:15336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002256
VERSION     KCWK01002256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20354:15336"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..432
                     /note="immunoglobulin light chain variable region"
     V_region        90..432
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67994.1"
                     /translation="DYYCAIGLSSGYIF"
     J_segment       399..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>473
                     /gene="IGLC"
BASE COUNT           91 a          156 c          119 g          107 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgtacctt cagcggtggc atcaatgttg
      181 ctggctacca cacacactgg taccagcaga agccagggag gcctccccgg tatcttctga
      241 gatacaaatc agactcagat aggggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgt ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggctca gcagcggtta catcttcggt actgggaccc
      421 ggctcaccgt cccaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002257             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:10174:7834
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002257
VERSION     KCWK01002257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:10174:7834"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..456
                     /note="immunoglobulin light chain variable region"
     V_region        108..456
     V_segment       108..416
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67995.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       419..456
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           99 a          159 c          125 g          111 t
ORIGIN      
        1 acatgggcaa cgcagagtac atgggggtgg ggaaagaggc tgtgtccacc atggcctgga
       61 ctcctctcct cctcctgctc ctctctcact gcacaggttc cctctccaag cctatgctga
      121 ctcagccggc ctccctctca gcatctcctg gaacatcagc cagtctcaca tgcaccttca
      181 gcggtggcat caatgttgtt ggctaccaca tacactggta ccagcagaag ccagggagtc
      241 ctccccggta tcttctgaga tacaaatcgg actcagataa gggccagggc tctggagtcc
      301 ccagccgctt ctctggatcc aaagatgctt cagcgaacgc agggatttta cgcatctctg
      361 gactccagtc tgaggatgag gctgactatt actgtgccat tgggcacagc agcggtgatt
      421 acatcttcgg tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg
      481 tcactctgtt cccg
//
LOCUS       KCWK01002258             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:5183:5281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002258
VERSION     KCWK01002258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:5183:5281"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    67..400
                     /note="immunoglobulin light chain variable region"
     V_region        67..400
     V_segment       67..363
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <331..>372
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67996.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       364..400
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        401..>438
                     /gene="IGLC"
BASE COUNT           78 a          149 c          116 g           95 t
ORIGIN      
        1 acatggggga ccccaatcct cctcctcctc ctcactctcc tccttcactg cacagggtct
       61 ctctcccagc ctgtgctgac tcagtcgccc tctgcctctg cctccctggg agcctcggtc
      121 aagctcacct gcactctgag cagtggacac aggagctaca ccatcgcgtg gcatcagcag
      181 cagcaaggga aggcccctcg atacttgatg tggcttaaag gtgatggcag ccacagcaag
      241 ggggacggga tccctgatcg cttctcaggc tccagctccg gggctgagcg ctacctcacc
      301 atctccaacc tccagtctga ggatgaggct gattattatt gtcagacgtg ggatattggc
      361 atttgggtgt tcggcggagg gacccggcta accgtcctag gtcagcccaa ggctgccccc
      421 tcggtcactc tcttcccg
//
LOCUS       KCWK01002259             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:15999:5773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002259
VERSION     KCWK01002259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15999:5773"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..387
                     /note="immunoglobulin light chain variable region"
     V_region        63..387
     V_segment       63..350
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <312..>359
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67997.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       351..387
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        388..>425
                     /gene="IGLC"
BASE COUNT           81 a          136 c          117 g           91 t
ORIGIN      
        1 acatgggggc ctggactttt ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg
       61 cctccgatga tctgactcag ccaccctcgg tgtcagtgtc cccaggacag acggccagga
      121 tcacctgtgg gggagacaac attggaagta agagtgtgca ctggtaccag cacaagccac
      181 cgcaggcccc tatcctggtc atctattatt ataccgaacg gccctcggcg atccctgagc
      241 gattctctgg ctccaaatca gggaacaccg ccaccctgac catcagcggg gtcgaggccg
      301 gggatgaggc tgactattac tgtcaggtgt gggacactac tattgatcat ggctttttcg
      361 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      421 tcccg
//
LOCUS       KCWK01002260             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:11660:8616
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002260
VERSION     KCWK01002260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11660:8616"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67998.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          156 c          127 g          112 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagtc tgagtggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002261             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:21901:9275
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002261
VERSION     KCWK01002261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21901:9275"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV67999.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       400..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          155 c          127 g          108 t
ORIGIN      
        1 acatgggggg tgtggctcag gaagcagagc ctggagcatc tccaccatgg cctgggctcc
       61 actcctcctc accctcctcg ctcactgcac agggtcttgg gctgacgttg tgttcactca
      121 gccccaatct gtgtcggggt ctccggggca gacggtcacc atctcctgca cccgcagcag
      181 tggcagcatt ggcaacagct atgtgtactg gttccagcag cggccgggca gcgtccccac
      241 tattgtgatt tacaaagatg accaaagacc ctctggggtc cctgatcggt tctctggctc
      301 catcgacagc tcctccaact ctgcctccct catcatctct ggactgaagt ctggggacga
      361 ggctgactat tactgtcagt cttttgacag cagcagtgtc ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002262             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:17215:18421
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002262
VERSION     KCWK01002262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17215:18421"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68000.1"
                     /translation="DYYCQTWETGIVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          161 c          120 g           99 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aaactcacct gcactctgaa cagtgggcac
      181 agcagctaca ccatcgcgtg gcatcagcaa cagcaaggga aggccccccg gtacttgatg
      241 tggcttaaaa ctgatggcag ccatagcaag ggggacggga tccctgatcg cttctcaggc
      301 tccagttccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggaaactggc attgtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002263             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:11291:12134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002263
VERSION     KCWK01002263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11291:12134"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..279
                     /note="immunoglobulin light chain variable region"
     V_region        5..279
     V_segment       5..242
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <204..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68001.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       245..279
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>317
                     /gene="IGLC"
BASE COUNT           75 a           90 c           84 g           68 t
ORIGIN      
        1 acatgggcag gatcacctgc tctggagcaa tactggcaaa taattatgct cagtggttcc
       61 agcagaagcc agaccaggcc cctgtgttgg tgatatataa agacactgag aggccctcag
      121 ggatccctga gcgattctct agctccagtt cagggacaac agttaccttg accatcagtg
      181 gggcccaggc agaagatgag gctgactatt actgtcaatc agttgacagc agtgcccatc
      241 atccgttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct
      301 cggtcactct cttcccg
//
LOCUS       KCWK01002264             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:26232:18409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002264
VERSION     KCWK01002264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:26232:18409"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68002.1"
                     /translation="DYYCQSYDSSLTGVLF"
     J_segment       416..450
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           92 a          156 c          127 g          113 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcagtgg gagcaactcc aacattggat actattatgt gcagtggtac cagcagcttc
      241 caggaacggc ccccaaactc ctcatctatg aaaataataa gcgaccctct ggggtttctg
      301 atcgattctc tggctcccag tctggtacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagtttgact ggtgtcttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01002265             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:8894:14749
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002265
VERSION     KCWK01002265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:8894:14749"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68003.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          160 c          122 g          108 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtact gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gaagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcaactgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag atgtatgaca gtagtgatgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002266             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:20476:7669
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002266
VERSION     KCWK01002266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20476:7669"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68004.1"
                     /translation="DYHCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          163 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccgc catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agtagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctccccggt
      241 tattcctgtt ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaaataaca cagcgttttt gctcatctct ggcctccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtatgacag tagtgcaaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002267             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:26326:10708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002267
VERSION     KCWK01002267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:26326:10708"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68005.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       412..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           90 a          155 c          129 g          113 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg agcagctcca acattggagg ttattatgtg cagtggtacc agcagcttcc
      241 agggacggcc cccaaactcc tcatctatga aaatgataaa cgaccctcag gggtttctga
      301 tcgattctct ggctcccagt ctgattcctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agcttgagtg ttgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01002268             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:18943:11952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002268
VERSION     KCWK01002268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18943:11952"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..394
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68006.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           85 a          159 c          119 g          113 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc gccctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcaa gctgccccga
      121 ctcagcctcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tattgggtct tataatgctg tgtcttggta ccaacagcgt ccaggcaaag
      241 ccccccaact catagttttt gaggtcaata agcggccctc aggggtctct gatcgcttct
      301 ctggctccaa ctctggcaac acggcctccc tgaccatctc tgggctccag gctgaggatg
      361 aggctgatta ttactgctgc tcatatgtag gcagcaacac ttacatcttc gatgttggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002269             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:25751:11246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002269
VERSION     KCWK01002269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:25751:11246"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68007.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           91 a          153 c          119 g          110 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat aatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaagacg gcctccctga ccatctctgg actccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacgcttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002270             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:8481:3316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002270
VERSION     KCWK01002270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8481:3316"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68008.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          129 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccacc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002271             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:16145:9523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002271
VERSION     KCWK01002271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16145:9523"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68009.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          165 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002272             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:27043:11587
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002272
VERSION     KCWK01002272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:27043:11587"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..395
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68010.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       396..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           93 a          152 c          121 g          104 t
ORIGIN      
        1 acatgggggg ggtacagaag gcaggactca ggacaatctc cagcatggcc tggttccctc
       61 tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg ctgactcagc
      121 ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct ggaagcagct
      181 ccaacatcgg aagtaataat gtgtcctggt accagcacct cccaggaaca gctcccaaac
      241 tcctcatcta ttataatgat caacgaggct caggtgtctc tgaccgattc tctggctcca
      301 agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat gaggctgatt
      361 attactgcgc agcgtgggat gataggctga gcagttacat cttcgctgct gggacccggc
      421 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002273             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17202:15948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002273
VERSION     KCWK01002273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17202:15948"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..336
                     /note="immunoglobulin light chain variable region"
     V_region        8..336
     V_segment       8..296
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68011.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       299..336
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           80 a          117 c           94 g           83 t
ORIGIN      
        1 acatgggggc ctccctctca gcatctcctg gaacatcagc cagtctcaca tgcaccttca
       61 gcggtggcat caatgttgct ggctaccaca tacactggta ccagcagaag ccagggagtc
      121 ctccccgata tcttctgaga tacaaatcgg actcagataa gggccagggc tctggagtcc
      181 ccagccgctt ctctggatcc aaagatgctt cagcgaacac agggatttta cgcatctctg
      241 ggctccagtc tgaggatgag gctgactatt actgtgccat tggacacagc agcggtgatt
      301 acatcttcgg tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg
      361 tcactctgtt cccg
//
LOCUS       KCWK01002274             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:23024:7812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002274
VERSION     KCWK01002274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:23024:7812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68012.1"
                     /translation="DYYCSSWESNLNLIF"
     J_segment       412..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          153 c          127 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaacatc ggggcgggtt tttatgtttc ctggtaccag caattcccag
      241 gaacagcccc caaactcctc atctttgaag ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattat tgttcatcat gggagagcaa cctgaatttg atattcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002275             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:20376:8918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002275
VERSION     KCWK01002275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20376:8918"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68013.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          157 c          120 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca cgaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaatgc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tccggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttattcttcg ggggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002276             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:7855:8965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002276
VERSION     KCWK01002276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7855:8965"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68014.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          158 c          128 g          107 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcagcact cagggacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tactgttgct catataggag tggaaacact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002277             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:24207:16831
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002277
VERSION     KCWK01002277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:24207:16831"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68015.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          140 c          137 g          102 t
ORIGIN      
        1 atggggagcc tgactttggg aagcagcctt ggcggtgcct cagccatggc cgggaccctt
       61 ctcctcctcg gcctccttgc tcactttaca ggctctgtgg cctcctatga gttgcctcag
      121 ccacgctcag tgtccgtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta atagtgtgca ttggtaccag cagaagccac cgcgggcccc tgtattggtc
      241 atctctgttg atagcgaacg gccctcaggg atccctgagc gattctctgg ttccagatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggataatat ttataaatac gcggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002278             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:23960:11431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002278
VERSION     KCWK01002278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23960:11431"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..453
                     /note="immunoglobulin light chain variable region"
     V_region        123..453
     V_segment       123..416
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68016.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       417..453
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           92 a          161 c          123 g          115 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactt cacagttcca gggtcctggg
      121 cccagtctgt gctgacgcag ccgccctcag tgtctggggc gcccggccag agggtcacca
      181 tctcctgcac tgggagcagc tccaacattg gagattattt tgtccagtgg taccagcacc
      241 ttccaggaac ggcccccaaa ctcctcatct atgaaaataa taagcgaccc tcagggattt
      301 ctgatcgatt ctctggctcc cagtctggaa cctcagcctc cctgaccatc actggactcc
      361 agtccgagga tgaggctgat tattactgcc agtcctatga cagcagtttg attgctgtgt
      421 tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      481 ctctcttccc g
//
LOCUS       KCWK01002279             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:21496:19278
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002279
VERSION     KCWK01002279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21496:19278"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..426
                     /note="immunoglobulin light chain variable region"
     V_region        103..426
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68017.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>465
                     /gene="IGLC"
BASE COUNT           91 a          146 c          130 g           98 t
ORIGIN      
        1 acatgggggt gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttatttg gaggagggac ccggctgacc
      421 gtcctaagtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002280             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:12922:19199
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002280
VERSION     KCWK01002280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12922:19199"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..415
                     /note="immunoglobulin light chain variable region"
     V_region        95..415
     V_segment       95..379
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68018.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       380..415
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>454
                     /gene="IGLC"
BASE COUNT           94 a          143 c          119 g           98 t
ORIGIN      
        1 acatgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc ctctcctact
       61 ccccatcctc actttctgca caggctctgc agcctcctat gagctgacac agccaccctc
      121 ggtgtcagtg tccccaggac agacggccaa gatcacctgc tctggagatg cactgccaaa
      181 aaaatatgct tattggttcc agcagaagcc aggccagtcc cctgtgttga tcatcgatga
      241 ggacaccaaa cggccctctg ggatccctga gagattctct ggctccagct cagggacagt
      301 ggccaccttg actatcagtg gggcccaggt ggaggatgaa gctgactact actgttactc
      361 agcagacagc agtggttatg gcttattcgg aggagggacc cggctgaccg tcctacgtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002281             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:7762:9488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002281
VERSION     KCWK01002281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:7762:9488"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..433
                     /note="immunoglobulin light chain variable region"
     V_region        88..433
     V_segment       88..396
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68019.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           93 a          160 c          109 g          109 t
ORIGIN      
        1 acagggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gaacatcagc cagactcagc tgcaccttga gcagtggcaa tgttggtagt
      181 tacagcatat tctggtacca gcagaagcca gggagtcctc cccggtacct tctttactac
      241 tactcagact caagtaacca ccaggactct ggagtcccca gccgcttctc tggatcgaaa
      301 gatgcttcag ccaatgcagg gcttttactg atctctgggc tccagtctga agatgaggct
      361 gactattact gtgccacatg gcacagcagc gcttcttaca tcttcggtcc tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01002282             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:13084:19330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002282
VERSION     KCWK01002282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13084:19330"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68020.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          101 a          137 c          123 g          102 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctggggcc tcctatgagg tgacacagtc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagcaatact
      181 ggcaaataat tatgctcagt ggttccagca gaagccagac caggcccctg tgttggtgat
      241 atataaagac actgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacaatt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagtt gacagcagtg cccatcatcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactcccttc ccg
//
LOCUS       KCWK01002283             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:12478:15318
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002283
VERSION     KCWK01002283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12478:15318"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..392
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68021.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       406..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           89 a          154 c          120 g          111 t
ORIGIN      
        1 acatggggct gggatctcag caggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccccgact
      121 cagactccct ctgtgtccgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgata ttgggtatta tcatgctgtg tcttggtacc agcatcatcc aggcaaagcc
      241 cccaaactca tgatttatga ggtcaataaa cggcccgcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccagac tgaggatgag
      361 gctgattatt actgtagctc atatgcaggc agcaacagtt tattcttcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002284             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:21020:14841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002284
VERSION     KCWK01002284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21020:14841"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..432
                     /note="immunoglobulin light chain variable region"
     V_region        108..432
     V_segment       108..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68022.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       395..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           89 a          150 c          134 g           97 t
ORIGIN      
        1 atgggggccc tgtctgggtc tcaggaggca gcattgacgg tgcctcagcc atggcctgga
       61 cccttctcct cctcggcctc ctcgctcact gcacaggctc tgcgacctcc tttgagctga
      121 ctcagccacc ctcggtgtca gcggcctcag gacagacggc caggatcacc tgtgggggag
      181 acaacattgg aattaaattt gtccactggt accagcagaa gccagcgcag gcccctgtga
      241 aggtcatcta tgctgatgac aaacggccct cagggatccc tgagagattc tctggctcca
      301 attcagggaa caccgccacc ctgaccatca gcggggtcga ggccggggat gaggctgact
      361 attcctgtca ggtgtgggac agtgagactg atcattacat cttcggtgct gggacccggc
      421 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002285             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:26010:11692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002285
VERSION     KCWK01002285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:26010:11692"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..441
                     /note="immunoglobulin light chain variable region"
     V_region        96..441
     V_segment       96..405
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68023.1"
                     /translation="DYYCMIWHNNAWVF"
     J_segment       406..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          153 c          119 g          111 t
ORIGIN      
        1 acatggggcc cactgcaggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcgcagcc tgtggtgact cagccaacct
      121 ccctctcagc agctcctgga gcatcagcca gactcacctg caccttgagc agtggcatca
      181 gtgttggtag ttacaggata ttctggtacc agcagaagcc agggagtcct ccccggtatc
      241 ttctgaatta ccacacagaa tcagataagc accagggctc tggagtcccc agccgcttct
      301 ctggatccaa agatgcttcg gccaatgcag ggattttact catctctggg ctccagtctg
      361 aggatgaggc tgactattac tgtatgattt ggcacaacaa tgcttgggta ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002286             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:22552:17770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002286
VERSION     KCWK01002286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22552:17770"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68024.1"
                     /translation="DYYCAAWDESLRGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           94 a          152 c          124 g           99 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgcgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtcaccatc tcctgttctg ggagcagctc
      181 caacatcgga agaaatagtg tatcctggta ccagcagctc ccaggaacag ctcccaaaat
      241 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctccaa
      301 gtctggcacg tcagccgccc tggccatcag cgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcatgggatg aaagcctgag gggttacatc ttcggtgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002287             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:19870:10233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002287
VERSION     KCWK01002287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19870:10233"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68025.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          138 c          133 g          103 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggaaagacgg ccaggatcac ctgtggggga gacaatattg
      181 gaagtgaagt tgtcaactgg taccagcaga agccaccgca ggcccctgtg gtggtcatct
      241 atgctgatta tgaacggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acacggccac cctgaccatc agcggagtcg aggccgggga tgaggctgac tattactgtc
      361 aggtttggga catttatatt gatcatccgg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002288             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:5212:4043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002288
VERSION     KCWK01002288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:5212:4043"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68026.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggacct ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002289             394 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:22990:8192
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002289
VERSION     KCWK01002289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 394)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22990:8192"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..356
                     /note="immunoglobulin light chain variable region"
     V_region        8..356
     V_segment       8..317
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>328
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68027.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       319..356
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        357..>394
                     /gene="IGLC"
BASE COUNT           85 a          121 c           92 g           96 t
ORIGIN      
        1 acatgggcag cctgtgctga ctcagccaac ctccctctca gcatctcctg gagcatcagc
       61 cagactcacc tgcaccttga acagtggcat cagtgttgct aattacagga tattctggta
      121 ccaccagaag ccagggagtc ctccccggta tcttctgaac taccacacag actcagatat
      181 tcatcagggc tctggagtcc ccagccgctt ctctggatcc aaagatgctt cggccaatgc
      241 agggatttta ctcatctctg gactccagtc tgaggatgag gctgactatt actgtatgat
      301 ttggcacaac aatgcttatt gggttttcgg cggagggacc cggctaaccg tcctaggtca
      361 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002290             345 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:12259:8698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002290
VERSION     KCWK01002290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 345)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12259:8698"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..307
                     /note="immunoglobulin light chain variable region"
     V_region        8..307
     V_segment       8..270
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <235..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68028.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       271..307
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>345
                     /gene="IGLC"
BASE COUNT           72 a          107 c           89 g           77 t
ORIGIN      
        1 acatgggcag ccagtctcac atgcaccttc agcggtggca tcaatgttgt tgcctaccac
       61 atacactggt accagcagaa gccagggagt cccccccggt atcttctgag gtacaaatca
      121 gactcagata agggccaggg cgctggagtc cccagccgct tctctggatc caataatgct
      181 tcagggaaca cagggatttt acgcatctct gggctccagt ctgaggatga ggctgactat
      241 tactgtgcca ttgggcacag cagcggtcct tacatcttcg gtgctgggac ccgtctcacc
      301 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002291             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:13561:4774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002291
VERSION     KCWK01002291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:13561:4774"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68029.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           94 a          146 c          129 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca gactctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccacga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atactaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002292             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:6835:9025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002292
VERSION     KCWK01002292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6835:9025"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..303
                     /note="immunoglobulin light chain variable region"
     V_region        87..303
     V_segment       87..266
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68030.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       267..303
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           67 a          100 c           99 g           75 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagc ggaagccagg ccagtcccct gtgttgatca
      121 tctatgagga caacaaacgg tcttctggga tcgctgagag attctctggc tccagctcag
      181 ggacagtggc caccttgagt atcagtgggg cccaggggga ggatgaagct gactactact
      241 gttactcagc agacagcagt ggtaatggct tattcggagg agggacccga ctgaccgtcc
      301 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002293             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:20654:3675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002293
VERSION     KCWK01002293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20654:3675"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..443
                     /note="immunoglobulin light chain variable region"
     V_region        95..443
     V_segment       95..403
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68031.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       406..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           93 a          159 c          116 g          113 t
ORIGIN      
        1 acatgggcaa cgcagagtac atggggctgt gtccaccatg gcctggactc ctctcctcct
       61 cctgctcctc tctcactgca caggttccct ctccaagcct atgctgactc agccggcctc
      121 cctctcagca tctcctggag catcagccag tctcacatgc accttcagcg gtggcatcaa
      181 tgttgctgac taccacgtac actggtatca gcagaagcca gggggtcccc cccggtatct
      241 tctgaggtac aaatcagact cagataaggg cctgggctct ggagtcccca gccgcttctc
      301 tggatccaaa gatgcttcag cgaatacagg gattttacac atctctggtt tccagtctga
      361 ggatgaggct gactattact gtgccattgg ccacggcagc ggtgattaca tcttcggtac
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01002294             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:7376:19680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002294
VERSION     KCWK01002294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7376:19680"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68032.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          159 c          121 g          110 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtctcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccggcac ctcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgataacct gagcggttac atcttcggtt
      421 ctgggacccg actcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01002295             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:11904:15371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002295
VERSION     KCWK01002295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11904:15371"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..392
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68033.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       394..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           89 a          146 c          124 g          110 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctcctct
       61 cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc tgacgcagcc
      121 gccctcagtg tctggggcgc ccgggcagag ggtcagtatt tcttgcactg ggagcagctc
      181 caacattgga ggttattatg tgcagtggta ccagcagctt ccaggaacgg cccccaaact
      241 cctcatctat gaaaatgata aacgaccctc agggatttct gatcgattct ctggctccca
      301 gtctgattcc tcagcctccc tgaccatcac tggactccag tctgaggatg aggctgatta
      361 ttactgccag tcctatgaca gcagcttgag tgttgtgtta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002296             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18483:4909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002296
VERSION     KCWK01002296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18483:4909"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68034.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          109 a          137 c          121 g           99 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg acctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagaagcca ggccagggcc ctacactggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagcgg ggcccagaca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagaa gtcctaatca tgtgtttttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002297             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:18414:4894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002297
VERSION     KCWK01002297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18414:4894"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68035.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          146 c          131 g           97 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gactctgcga cctcctttga gctgactcag
      121 ccaccctcgg tgtcagtggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaatta aatttgtcca ctggtaccag cagaagccag cgcaggcccc tgtgaaggtc
      241 atctatgctg atgacaaacg gccctcaggg atccctgaga gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattcc
      361 tgtcaggtgt gggacagtga gactgatcat tacatcttcg gtgttgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002298             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:25099:15910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002298
VERSION     KCWK01002298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:25099:15910"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..265
                     /note="immunoglobulin light chain variable region"
     V_region        7..265
     V_segment       7..228
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <193..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68036.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       229..265
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           68 a           87 c           78 g           70 t
ORIGIN      
        1 acatggggtg gtaaaaacat gtactggtat cagcagaagc cagggcgcgc tcccaggttt
       61 ttcctgtact acaactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      121 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      181 gaagacgagg ccgattatta ctgtcacgta tatgacagta gtactaatgt gttattcgga
      241 ggagggaccc gtctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      301 ccg
//
LOCUS       KCWK01002299             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:8425:8895
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002299
VERSION     KCWK01002299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8425:8895"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..388
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68037.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       390..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          149 c          121 g          107 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag cagctccaac
      181 attggaggtt attatgtgca gtggtaccag cagcttccag gaacggcccc caaactcctc
      241 atctatgaaa atgataaacg accctcaggg gtttctgatc gattctctgg ctcccagtct
      301 gattcctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgccagtcct atgacagcag cttgagtgtt gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002300             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:20144:19346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002300
VERSION     KCWK01002300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20144:19346"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68038.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          163 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cccctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002301             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:15916:16104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002301
VERSION     KCWK01002301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15916:16104"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68039.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       409..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           97 a          156 c          117 g          110 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggaac atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctggct accacatata ctggtaccac cagaagccag ggagtccccc ccggtatctt
      241 ctgaggtaca aatcagactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc gaacacaggg attttacaca tctctggact ccagtctgag
      361 gatgaggctg actattactg tgccattgga cacagcagcg gtgattatat cttcggtggt
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002302             342 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:19277:17844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002302
VERSION     KCWK01002302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 342)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19277:17844"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    2..304
                     /note="immunoglobulin light chain variable region"
     V_region        2..304
     V_segment       2..265
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <232..>276
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68040.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       274..304
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        305..>342
                     /gene="IGLC"
BASE COUNT           72 a          109 c           83 g           78 t
ORIGIN      
        1 acatgggggg cccccggaca gagggtcacc atctcctgca ttagcagcag ctccaacatc
       61 ggggcggctt attatgtatc ctggtaccaa cagttcccag gaacagcccc caaactcctc
      121 atctttgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      181 ggtccctcag cctccctgac catcactgga ctccaatctg aggatgaggc tgattattac
      241 tgtttagcat gggataccag cctgaattgg atcttcggcg gagggacccg gctgaccgtc
      301 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002303             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:7910:19347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002303
VERSION     KCWK01002303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:7910:19347"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..252
                     /note="immunoglobulin light chain variable region"
     V_region        8..252
     V_segment       8..215
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <177..>224
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68041.1"
                     /translation="DYYCAAWDDRLTSYIF"
     J_segment       216..252
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        253..>290
                     /gene="IGLC"
BASE COUNT           60 a           91 c           73 g           66 t
ORIGIN      
        1 acatgggcgg aagtaataat gtgtcctggt accagcacct cccaggaaca gctcccaaac
       61 tcctcatcta ttataatgat caacgaggct caggtgtctc tgaccgattc tctggctcca
      121 agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat gaggctgatt
      181 attactgcgc agcgtgggat gataggctga ccagttacat cttcgctgct gggacccggc
      241 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002304             310 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:20120:6237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002304
VERSION     KCWK01002304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 310)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20120:6237"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..272
                     /note="immunoglobulin light chain variable region"
     V_region        8..272
     V_segment       8..232
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>244
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68042.1"
                     /translation="DYYCQVWDISTDHPVLF"
     J_segment       236..272
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        273..>310
                     /gene="IGLC"
BASE COUNT           66 a           87 c           91 g           66 t
ORIGIN      
        1 acatgggtgt ggaggagaca accttggata tgaagttgtc aactggtacc agcagaagcc
       61 accgcaggcc cctgtggtgg tcatctatgc tgattatgaa cggccctcag ggatccctaa
      121 ccgattctct ggctccaaat cagggaacac ggccaccctg accatcagcg gagtcgaggc
      181 cggggatgag gctgactatt attgtcaggt gtgggacatt agtactgacc atccggtgtt
      241 attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac
      301 tctcttcccg
//
LOCUS       KCWK01002305             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:7882:13996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002305
VERSION     KCWK01002305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7882:13996"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68043.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           93 a          160 c          109 g          111 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggaacatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatttctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt cctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002306             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:12563:6039
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002306
VERSION     KCWK01002306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12563:6039"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..390
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68044.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       391..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           85 a          156 c          125 g           99 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 actctcctcc ttcactgcac agggtctctc tcccagcctg tgctgactca gtcgccctct
      121 gcctctgcct ccctgggagc ctcggtcaag ctcacctgca ctctgagcag tggacacagg
      181 agctacacca tcgcgtggca tcagcagcag caagggaagg cccctcgata cttgatgtgg
      241 cttaaaagtg atggcagcca cagcaagggg gacgggatcc ctgatcgctt ctcaggctcc
      301 agctccgggg ctgagcgcta cctcaccatc tccaacctcc agtctgagga tgaggctgat
      361 tattattgtc agacgtggga tattggcatt tgggtgttcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002307             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:8203:8344
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002307
VERSION     KCWK01002307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:8203:8344"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68045.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          154 c          111 g          118 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcttc tcctggagca tcagtcagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttgctaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002308             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:5468:15363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002308
VERSION     KCWK01002308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5468:15363"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68046.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           94 a          156 c          122 g          110 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata gtgtttcctg gtaccagcaa ctcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaacgacc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagcggttac attttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01002309             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:10794:15587
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002309
VERSION     KCWK01002309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10794:15587"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..258
                     /note="immunoglobulin light chain variable region"
     V_region        5..258
     V_segment       5..222
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <186..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68047.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       226..258
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           67 a           83 c           85 g           61 t
ORIGIN      
        1 acatgggaga caacattgga actaaaactg tgcactggta ccaacagaag ccaccgcagg
       61 gccctgtatt ggtcatcttt gctgatagta gacggccctc agggatccct gagcgattct
      121 ctggctccaa ttcagggaac accgccaccc tgaccatcag cagggtcgag gccggggatg
      181 aggctgacta ttactgtcag gtgtgggaca gtagtagtaa atggatattc ggcgggggga
      241 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcctg
//
LOCUS       KCWK01002310             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:11279:5878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002310
VERSION     KCWK01002310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11279:5878"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68048.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           95 a          157 c          124 g          108 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aagagtgtca ccatctcctg
      181 ttctggaagc agctccaaca tcggaagtaa taatgtgtcc tggtaccagc acctcccagg
      241 aacagctccc aaactcctca tctattataa tgatcaacga ggctcaggtg tctctgaccg
      301 attctctggc tccaagtctg gcacgtcagc ctccctggcc atcagtgggc tccagaccga
      361 ggatgaggct gattattact gcgcagcgtg ggatgatagc ctgagcagtt acatcttcgc
      421 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01002311             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:18381:16053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002311
VERSION     KCWK01002311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18381:16053"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..403
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68049.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       408..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           92 a          159 c          114 g          115 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ttctcagcat ctccgggagc atcagtcaga ctcagctgca ccttgagcag tggcatcaat
      181 gttggttctt acaccatatt ctggtaccag cagaagccag ggagtcctcc ccggttcctt
      241 ctgtactact actcagactc aaataatcac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc caatgcaggg cttttactga tctctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccatgtgg cacagcagcg cttatgcctt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002312             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:19667:5526
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002312
VERSION     KCWK01002312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19667:5526"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68050.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          155 c          120 g          110 t
ORIGIN      
        1 acatggaggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002313             503 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:20345:14085
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002313
VERSION     KCWK01002313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 503)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 503)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..503
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20345:14085"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    193..465
                     /note="immunoglobulin light chain variable region"
     V_region        193..465
     V_segment       193..429
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <393..>437
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68051.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       430..465
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        466..>503
                     /gene="IGLC"
BASE COUNT           92 a          165 c          131 g          115 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggtgacacc tccagggaag gggcttctgg
      121 gtccttgact gatccttggt ctcctgctcc tcaggctcac ctgggcccag cactgactca
      181 ctggactgtg tttctcctgc actggaacca gcagtgacat cggtggttat aactatgtct
      241 cctggtacca acagcatcca ggcacagccc ccaaagtcat gatttatgag gtcagtaagc
      301 ggccctcagg ggtctctgat cgcttctctg gctccaagtc tggcaacacg gcctccctga
      361 ccatctctgg gctccaggct gaggacgagg ctgattatta ctgcagctca tatacaggca
      421 tcaacagtta catcttcggt ggtgggaccc ggctcaccgt cctaggtcag cccaaggctt
      481 cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002314             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:20638:3290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002314
VERSION     KCWK01002314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20638:3290"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..275
                     /note="immunoglobulin light chain variable region"
     V_region        8..275
     V_segment       8..240
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <203..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68052.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       242..275
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>313
                     /gene="IGLC"
BASE COUNT           66 a           89 c           81 g           77 t
ORIGIN      
        1 acatgggtgc actggaacca gcagtgatgt tgggtattat aacgctgtgt cttggtacca
       61 acagcatcca ggcaaagccc ccaaactcat gatttatgac gtcattaagc ggccctcagg
      121 ggtttctgat cgcttctctg gctccaagtc tggcgacacg gcctccctga ccatctctgg
      181 gctccaggct gaggatgagg ctgattatta ctgcagctca tatgcaggca gaaataattt
      241 tttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      301 cactctcttc ccg
//
LOCUS       KCWK01002315             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:18683:8708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002315
VERSION     KCWK01002315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18683:8708"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..271
                     /note="immunoglobulin light chain variable region"
     V_region        8..271
     V_segment       8..227
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <199..>243
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68053.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       234..271
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        272..>309
                     /gene="IGLC"
BASE COUNT           62 a           93 c           76 g           78 t
ORIGIN      
        1 acatgggctg gaaccggcag tgattttggg tcttataatg ctgtgtcttg gtaccaacag
       61 catccaggca aagcccccca actcataatt tttgaggtca ataagcggcc ctcaggggtc
      121 tctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc
      181 caggctgagg atgaggctga ttattactgc tgctcatatg taggcagcaa cacttacatc
      241 ttcgatgttg ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact
      301 ctgttcccg
//
LOCUS       KCWK01002316             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11743:17698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002316
VERSION     KCWK01002316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11743:17698"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..437
                     /note="immunoglobulin light chain variable region"
     V_region        93..437
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68054.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>479
                     /gene="IGLC"
BASE COUNT           93 a          153 c          119 g          114 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagct tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtata ccacatatat tggtaccagc agaagccagg gagtcccccc cggtttcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagtagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtcata ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002317             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:24792:12447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002317
VERSION     KCWK01002317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24792:12447"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    77..422
                     /note="immunoglobulin light chain variable region"
     V_region        77..422
     V_segment       77..383
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68055.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       385..422
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           83 a          158 c          113 g          106 t
ORIGIN      
        1 acatggggcc gtgtccacca tggccctgac tcctctcctc ctcctgctcc tctctcactg
       61 cacaggttcc ctctcccagc ctgtgctgac tcagccaccc tccctgtctg catccccggg
      121 agcatcggcc agactcccct gcaccctgag cagtgacctc agtgttggta gtaaaaacat
      181 gtactggtac cagcagaagc cagggagcgc tcccaggtta ttcctgtact actactccga
      241 ctcagacaag cagctgggac ctggggtccc caatcgagtc tctggctcca aggagacctc
      301 aagtaacaca gcgtttttgc tcatctctgg gctccagcct gaggacgagg ccgattattt
      361 ctgccaggtg tttgacagta gtgttgtgtt cttcggagga gggacccgac tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002318             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:8589:15341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002318
VERSION     KCWK01002318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8589:15341"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68056.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       395..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           92 a          149 c          132 g           96 t
ORIGIN      
        1 acatggggct ggcttcagaa gcagcatctg ggacatgtca gccatggcct ggacgcctct
       61 cctcctcagc ctcctcgctc actgcacagg ctctgtggcc tcctatgagc tgactcagcc
      121 accctcagtg tcggtgtccc caggacagac agccagcatc acctgctctg gaaataaatt
      181 ggggaatgta tatgcttact ggttccagca gaagccaggc caggcccctg tagtggtcat
      241 ctacaaagat accaaccggc cctcagggat ccctgagcga ttctctggct ccgactcagg
      301 gaacacggcc accctgacca tcagcagggt cgaggctggg gatgaggccg actatttttg
      361 tgctgcagcc tatggcagtg gcagcagctg gcagtgggta ttcggcggag ggacccggct
      421 aatcgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002319             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:5714:17668
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002319
VERSION     KCWK01002319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5714:17668"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..395
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68057.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       409..439
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           91 a          154 c          121 g          111 t
ORIGIN      
        1 acatgggggt gctgggatct caggaggcag cgctctcagg acttctccac catggtctgg
       61 gctctgctcc tcctcaccct cctcactcag ggcacaggat cctgggctca ggctgccccg
      121 actcagactc cctctgtgtc cgggtctcct ggacagtcgg tcaccatctc ctgcactgga
      181 accagcagtg atattgggta ttatcatgct gtgtcttggt accaacatca tccaggcaaa
      241 gcccccaaac tcataattta tgaggtcaat aaacggcccg caggggtctc tgatcgcttc
      301 tctggctcca agtctggcaa gacggcctcc ctgaccatct ctggactcca gactgaggat
      361 gaggctgatt attactgcag ctcatatgca ggcagcaacg ctttattctt cggaggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002320             319 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12456:18209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002320
VERSION     KCWK01002320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 319)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 319)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12456:18209"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..279
                     /note="immunoglobulin light chain variable region"
     V_region        8..279
     V_segment       8..242
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <209..>253
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68058.1"
                     /translation="DYYCSIGHSSGLYIF"
     J_segment       244..279
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>319
                     /gene="IGLC"
BASE COUNT           64 a           95 c           84 g           76 t
ORIGIN      
        1 acatgggggt ggcatcaatg ttgctgtcta ccacatacac tggtaccagc agaagccagg
       61 gagtcccccc cggtttcttc tgaggtacaa atcagactca gataagggcc agggctctgg
      121 agtccccagc cgcttctctg gatccagtaa tgcttcagcg aacacaggga ttttacgcat
      181 ttctgggctc cagtctgagg atgaggctga ctattactgt tccattggac acagcagcgg
      241 tctttacatc ttcggtgctg ggacccggct caccgtcctg ggtcagccca aggcttcccc
      301 cacggtcact ctgttcccg
//
LOCUS       KCWK01002321             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:21681:4518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002321
VERSION     KCWK01002321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:21681:4518"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68059.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          160 c          113 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtccgactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002322             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:25015:12399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002322
VERSION     KCWK01002322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:25015:12399"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..268
                     /note="immunoglobulin light chain variable region"
     V_region        7..268
     V_segment       7..231
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <193..>240
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68060.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       232..268
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        269..>306
                     /gene="IGLC"
BASE COUNT           64 a           90 c           76 g           76 t
ORIGIN      
        1 acatggggga gcagctccaa cattggagat ttttatgtgc agtggtacca gcaccttcca
       61 ggaacggccc ccagactcct catctatgaa aataataagc gaccctcagg ggtttctgat
      121 cgattctctg gctcccagtc tggaacctca gcctccctga ccatcactgg actccagtct
      181 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtttgattgc tgtgttattc
      241 ggaggaggga cccggttgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      301 ttcccg
//
LOCUS       KCWK01002323             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:14833:3499
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002323
VERSION     KCWK01002323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14833:3499"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..426
                     /note="immunoglobulin light chain variable region"
     V_region        96..426
     V_segment       96..389
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68061.1"
                     /translation="DYYCAAWDNSLTSPLL"
     J_segment       392..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          155 c          113 g          105 t
ORIGIN      
        1 acatgggaca gaaggcagga ctcaggataa tctccagcat ggcctggttc cctctcgtcc
       61 tcaccctcct cactcactgt gcagggtcct gggcccagtc tgtgctgact cagccaccct
      121 cagcgtctgg ggctcccggg cagagtgtca ccatctcttg ctctggaagc agctccaaca
      181 ttcgaactaa ttatgtatac tggtaccagc agctcccagg aacggccccc aaagtcctca
      241 tctattatag taatcagcga ccctcagggg tccctgaccg attctctgcc tctaagtctg
      301 gcacctcagc ctccctggcc atcactggtc tccgatctga ggatgaggct gattattact
      361 gtgcagcgtg ggataacagc ctaactagtc cgttactcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002324             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:17557:20025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002324
VERSION     KCWK01002324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17557:20025"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..390
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68062.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          156 c          120 g          100 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 actctcctcc ttcactgcac agggtctctc tcccagcctg tgctgactca gtcgccctct
      121 gtctctgcct ccctgggagc ctcggtcaaa ctcacctgta ctttgaacag tgggcacagc
      181 agctacacca tcgcatggca tcagcagcag caagggaagg ccccccggta cttgatgtgg
      241 cttaaaagtg aaggcagcca tagcaagggg gacgggatcc ctgatcgctt ctcaggctcc
      301 agctccgggg ctgagcgcta cctcaccatc tccaacctcc agtctgagga tgaggctgat
      361 tattactgtc agacctggga tactgacatt gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002325             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:23412:20578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002325
VERSION     KCWK01002325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23412:20578"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68063.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          157 c          128 g          111 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga ggagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagtc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002326             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:25186:7251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002326
VERSION     KCWK01002326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:25186:7251"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68064.1"
                     /translation="DYYCCSYRSGPTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          159 c          124 g          109 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt ataatggcgt ctcctggtac caacaacact cagggacagc
      241 ccccaaactc ctgatttatg atctgaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgctgct catataggag tggacccact tgggttttcg tcggagggac
      421 ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002327             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11448:18351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002327
VERSION     KCWK01002327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11448:18351"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68065.1"
                     /translation="DYYCAAWDDRLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          157 c          127 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcgggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatcgcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002328             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:11795:4595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002328
VERSION     KCWK01002328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11795:4595"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68066.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       414..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           91 a          157 c          125 g          115 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcacttcac agttccaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag attattttgt gcagtggtac cagcaccttc
      241 caggaacggc ccccaaactc ctcatctatg aaaataataa gcggccctca gggatttctg
      301 atcgattctc tggctcccag tctggaacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagtttgatt gctgtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01002329             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18421:5952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002329
VERSION     KCWK01002329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18421:5952"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68067.1"
                     /translation="DYYCQVWDIYTDHPVIF"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          142 c          135 g          101 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag cctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtcaac tggtaccagc agaagccacc gcaggcccct gtggtggtca
      241 tctatgctga ttatgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcggag tcgaggccgg ggatgaggct gactattact
      361 gtcaggtttg ggacatttat actgatcatc cggtgatatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002330             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:20313:3744
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002330
VERSION     KCWK01002330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20313:3744"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68068.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       414..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          158 c          123 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccggaca gagggtcacc atctcctgca
      181 ttagcagcag ctccaacatc ggggcggctt attatgtatc ctggtaccaa cagttcccag
      241 gaacagcccc caaactcctc atctttgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtccctccg cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattac tgtttagcat gggataccag cctgaattgg atcttcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002331             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:10631:11404
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002331
VERSION     KCWK01002331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10631:11404"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68069.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           83 a          161 c          123 g          101 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtggccac
      181 tacagctaca ccatcgcatg gcatcagcag cagcaaggga aggcccctcg gttcttgatg
      241 tggcttaaga gtgatggcag ccacaccaag ggggacgggg tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatattggc atttgggtat tcggcggagg gacccggcta
      421 atcgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002332             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:20242:4931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002332
VERSION     KCWK01002332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20242:4931"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68070.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          159 c          113 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002333             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:12284:17991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002333
VERSION     KCWK01002333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:12284:17991"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68071.1"
                     /translation="VYFCAIGHSSGPYIF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           95 a          162 c          109 g          108 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcaactcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 gcctaccaca tacactggta ccaacagaag ccagggagtc ccccccggta tcttctgagt
      241 tacaaatcag actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaaaatgctt caacgaacac aggcatttta cacatctctg ggctccagtc tgacgatgag
      361 gctgtctatt tctgtgccat tggacacagc agcggtcctt acatcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01002334             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:16084:18678
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002334
VERSION     KCWK01002334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16084:18678"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68072.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       388..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           92 a          146 c          119 g          105 t
ORIGIN      
        1 acatgggggg gctcagaagc agaactctgg gtcctctcca ccatggcctg gacccctccc
       61 ctgctcatcc tcctcactct ctgcacaggt tccgtggttt cctctgagct gactcaggag
      121 cctgcattgt ctgtggcctt gggacataca gtcaggatga cctgccaagg agacagcctc
      181 aaaacctatt atgcaagctg gtaccagcag aagccaggcc aggtccctgt gctggtcatc
      241 tatggtaaca actaccggcc ctcagggatc ccaggccgat tctctgtctc ctggtcagga
      301 aacacaggtt ccttgaccat cactgcggct caggtggaag atgaggctga ctattattgt
      361 aagtcctggg acagcagtgg tacccattac atcttcggtg ctgggacccg gctcaccgtc
      421 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002335             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:9111:19174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002335
VERSION     KCWK01002335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9111:19174"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..227
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68073.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       231..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           67 a           86 c           89 g           59 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaactaa aactgtgcac tggtaccaac agaagccacc
       61 gcagggccct ctattggtca tctttgctga tagtagacgg ccctcaggga tccctgagcg
      121 attctctggc tccaactcag ggaacaccgc caccctgacc atcagcaggg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg
      241 ggggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01002336             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:18748:6901
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002336
VERSION     KCWK01002336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18748:6901"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68074.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          138 c          139 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcaggc
      121 accctcgatt tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 gtatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacatgaata gtcatcatct gttattcgga ggggggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002337             342 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:18071:9217
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002337
VERSION     KCWK01002337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 342)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18071:9217"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    2..304
                     /note="immunoglobulin light chain variable region"
     V_region        2..304
     V_segment       2..265
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <232..>276
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68075.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       267..304
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        305..>342
                     /gene="IGLC"
BASE COUNT           67 a          105 c           89 g           81 t
ORIGIN      
        1 acatgggggg cccccgggca gagggtcacc atctcctgct ctgggagcag ctccaacatc
       61 ggggcgggtt tttatgtttc ctggtaccag cagttcccag gaacagcccc caaactcctc
      121 atctttgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      181 ggttcctcag cctccctgac catcactgga ctccaatctg aggatgaggc tgattattat
      241 tgttcatcat gggaaagcag cctgaattgg gtattcggcg gagggacccg gctgaccgtc
      301 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002338             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:17396:11098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002338
VERSION     KCWK01002338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:17396:11098"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68076.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          147 c          132 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgggcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002339             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16159:9628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002339
VERSION     KCWK01002339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16159:9628"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..254
                     /note="immunoglobulin light chain variable region"
     V_region        8..254
     V_segment       8..217
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68077.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       222..254
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           59 a           91 c           76 g           66 t
ORIGIN      
        1 acatgggatt ggaagtaatt ctgtatactg gtaccagcag ttcccaggaa cggcccccaa
       61 actcctcatc tattatagta atcagcgacc ctcaggggtc cctgaccgag tctctggctc
      121 taagtcgggc acctcagcct ccctggccat cactggtctc cgatctgagg atgaggctga
      181 ttattactgt gcagcatggg atgacagcct gagaagtccg ctattcggcg gagggacccg
      241 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002340             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:13996:19327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002340
VERSION     KCWK01002340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13996:19327"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68078.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          156 c          122 g          108 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggtacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcagc ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct
      181 ggaagcagct ccaacatcgg aagtaataat gtgtcctggt accagcacct cccaggaaca
      241 gctcccaaac tcctcatcta ttataatgat caacgaggct caggtgtctc tgaccgattc
      301 tctggctcca agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat
      361 gaggctgatt attactgcgc agcgtgggat gatagcctga gcagttacat cttcgctgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002341             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:21916:9973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002341
VERSION     KCWK01002341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21916:9973"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    62..392
                     /note="immunoglobulin light chain variable region"
     V_region        62..392
     V_segment       62..357
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <320..>364
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68079.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       362..392
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>430
                     /gene="IGLC"
BASE COUNT           82 a          141 c          106 g          101 t
ORIGIN      
        1 acatggggtc tgggctctgc tcctcctcac cctcctcact cagggcacag gatcctgggc
       61 tcaggctgcc ccgactcaga ctccctctgt gtccgggtct cctggacagt cggtcaccat
      121 ctcctgcagt ggaaccagca gtgatattgg gtattatcat gctgtgtctt ggtaccaaca
      181 tcgtccaggc aaagccccca aactcatgat ttatgaggtc aataaacggc ccgcaggggt
      241 ctctgatcgc ttctctggct ccaagtctgg caacacggcc tccctgacca tctctgggct
      301 ccagactgag gatgaagctg attattactg cagctcatat gcaggcagca acactttatt
      361 cttcggacga gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac
      421 tctcttcccg
//
LOCUS       KCWK01002342             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:9760:2671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002342
VERSION     KCWK01002342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9760:2671"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..390
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68080.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       397..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           83 a          159 c          126 g           97 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 actctcctcc ttcactgcac agggtctctc tcccagcctg tggtgactca gtcgtcctct
      121 gcctctgcct ccctgggagc ctcggtcaag ctcacctgca ctctgagcgg tgggcacagc
      181 gactacacca tcgcatggca tcagcagcag caagggaagg cccctcggta tttgatgtgg
      241 cttaaaagtg atggcagcca cagcaagggg gacgggatcc ctgatcgctt ctccggctcc
      301 agctccgggg ctgagcgcta cctcaccatc tccaacctcc agtctgagga tgaggctgat
      361 tattactgtc agacctggga gactggcatt caggtgttcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002343             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:12749:12939
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002343
VERSION     KCWK01002343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12749:12939"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    75..396
                     /note="immunoglobulin light chain variable region"
     V_region        75..396
     V_segment       75..360
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <324..>368
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68081.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       364..396
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        397..>434
                     /gene="IGLC"
BASE COUNT           88 a          138 c          120 g           88 t
ORIGIN      
        1 acatgggtgc ctcagccatg gcctggaccc ttctcctcct cggcctcctc gcttactgca
       61 caggctctgc gacctcctat gaactgactc agtcaccctc agtgtcagcg gcctcaggac
      121 agccggccag gatcacctgt gggggagacg acattggaac taaaactgta cactggtacc
      181 agcagaagcc accgcagggc cctgtattgg tcatctttgc tgatagtaaa cggccctcag
      241 ggatccctga gcgattctct ggctccaact cagggaacac cgccaccctg accatcagca
      301 gggtcgaggc cggggatgag gctgactatt actgtcaggt gtgggacagt agtagtaaat
      361 ggatattcgg cggggggacc cggctaaccg tcctaggtca gcccaaggct gccccctcgg
      421 tcactctctt cccg
//
LOCUS       KCWK01002344             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:24805:9505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002344
VERSION     KCWK01002344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24805:9505"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..252
                     /note="immunoglobulin light chain variable region"
     V_region        8..252
     V_segment       8..215
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <177..>224
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68082.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       216..252
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        253..>290
                     /gene="IGLC"
BASE COUNT           56 a           93 c           75 g           66 t
ORIGIN      
        1 acatgggcgg aagtcatagt gtctcctggt accagcaact cccaggaaca gctcccaaac
       61 tcctcatcta ttatagtgat caacgagcct caggtgtctc tgaccgattc tctggctccc
      121 agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat gaggctgatt
      181 attactgcgc ggcatgggat gatagcctga gcggttacat cttcggtgct gggacccggc
      241 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002345             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:11390:18167
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002345
VERSION     KCWK01002345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11390:18167"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68083.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       389..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           86 a          139 c          135 g          101 t
ORIGIN      
        1 acatggggac tttgggaagc agccttggcg gtgcctcagc catggccggg acccttctcc
       61 tcctcggcct ccttgctcac tttacaggct ctgtggcctc ctatgagttg cctcagccac
      121 gctcagtgtc cgtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtaatag tgtgcattgg taccagcaga agccaccgcg ggcccctgta ttggtcatct
      241 ctgttgatag cgaacggccc tcagggatcc ctgagcgatt ctctggttcc agatcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga taatatttat aaatacgcgg tattcggcgg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002346             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:8988:18003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002346
VERSION     KCWK01002346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8988:18003"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68084.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       409..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           87 a          154 c          132 g          111 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctctccttc tcactctgct ggttcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagcatctgg ggcccccggg cagagggtta ccatctcctg
      181 cactgggagc agctccaaca tcggggcggg tttttatgtg tcctggtacc agcagttccc
      241 tgggacagcc cccaaactcc tcatctttga aaataataag cgaccctcag gggtttctga
      301 ccgattctct ggctccaagt ctggttcctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgctcatc atgggaaagc agcctgaatt gggtattcgg
      421 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01002347             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12006:2640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002347
VERSION     KCWK01002347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12006:2640"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68085.1"
                     /translation="DYYCQVWDSTSDHYIF"
     J_segment       389..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          152 c          131 g           93 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag gctctgcgac ctcctatgag ctgactcagc
      121 caccctcggt gtcagcggcc tcaggacaga cggccagggt cacctgtggg ggagacaaca
      181 ttggaactac gtttgtccac tggtaccagc agaatccacc gcaggcccct gtgcaggtca
      241 tctttgcgga taacaaacgg ccctcaggga tccctgaacg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtact agtgatcatt acatcttcgg tggtgggacc cgcctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01002348             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:21220:6975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002348
VERSION     KCWK01002348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21220:6975"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68086.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       403..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           92 a          161 c          111 g          113 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtac tgacccagcc aacctccctc
      121 tcagcatctc cgggagcatc agccagactc agctgcacct tgagcagtgg catcaatgtt
      181 ggtagttaca gcgtattctg gtaccagcag aagccaggga gtcctccccg gttccttctg
      241 tactactact cagactcaag taaacaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcggccaa tgcaggcctt ttactgatct ctaggctcca gtctgaagat
      361 gaggctgact attactgtgc catatggcac agcagcgctt cttacttctt cggtactggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01002349             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:14959:18413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002349
VERSION     KCWK01002349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14959:18413"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..434
                     /note="immunoglobulin light chain variable region"
     V_region        109..434
     V_segment       109..399
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68087.1"
                     /translation="DYYCQSADGNYRVF"
     J_segment       400..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>473
                     /gene="IGLC"
BASE COUNT           86 a          163 c          123 g          101 t
ORIGIN      
        1 acatgggggg ctgtgactca gaaagcagag cctggggcgt ctccaccatg gcctgggctc
       61 cactcctcct caccctcctc gctcactgca cagggtcttg ggctgaactt gtgttcactc
      121 agccccattc tgtgtcgggg tctccggggc agacggtcac catctcctgc acccgcagca
      181 ttggcaacat tgacagtgaa tatgtgcagt ggtaccagca gcgcccgggc agtgccccca
      241 ccacactgat ttacaaagat agtcaaagac cctctggggt ccctgaccgg ttctctggct
      301 ccatcgacag ctcctccaac tctgcctccc tcgccatctc tgggctacag tctgaggacg
      361 aggctgacta ctactgtcag tctgctgatg gcaactacag ggtcttcggc ggagggaccc
      421 ggctaaccgt cctaagtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002350             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:7893:14855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002350
VERSION     KCWK01002350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7893:14855"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68088.1"
                     /translation="DYYCAIWHSSASYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          164 c          108 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcttc tccgggagca tcagccagac tcagctgcac cttgaacagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tttactacta ctcagactca acttaccacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacatc ttcggtcctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002351             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:11981:18416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002351
VERSION     KCWK01002351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11981:18416"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68089.1"
                     /translation="DYYCSSYAGRNNILF"
     J_segment       402..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           89 a          151 c          121 g          112 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggttcaggct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tggatattat aacgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 ccaaactcat aatttttgac gtcattaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcgacacg gcctccctga ccatctctgg gctccgggct gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gaaataatat tttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002352             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:19609:13398
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002352
VERSION     KCWK01002352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19609:13398"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..282
                     /note="immunoglobulin light chain variable region"
     V_region        8..282
     V_segment       8..245
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <210..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68090.1"
                     /translation="EHYCLLYYSGAQLLF"
     J_segment       247..282
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>320
                     /gene="IGLC"
BASE COUNT           66 a          100 c           80 g           74 t
ORIGIN      
        1 acatgggtct cacctgtgct tccagcactg gagcagtcac cagtggtcac tctccacact
       61 ggttccagca gaaacctgga caagccccca agacactgat ttataataca aactacagac
      121 actcctggac tcctgcccgg ttctcaggct ccctccttgg gggtaaagct gccctgacac
      181 tgtcaggtgc gcagcctgag gatgaggctg agcattattg tttactgtac tatagtggtg
      241 ctcagctgtt attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      301 cctcggtcac tctcttcccg
//
LOCUS       KCWK01002353             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:9181:5184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002353
VERSION     KCWK01002353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9181:5184"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..409
                     /note="immunoglobulin light chain variable region"
     V_region        79..409
     V_segment       79..370
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68091.1"
                     /translation="VYYCGAWDSSLSGYIF"
     J_segment       372..409
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           85 a          147 c          112 g          103 t
ORIGIN      
        1 acatggggga caatcttcat catgacctgg tcccctctcc tcctcaccct tctcattcac
       61 tgcacagggt cctgggccca gtctgtgctg acgcagccgc cctcagtgtc tacggcccca
      121 gggcagaagg tcaccatctc ctgctctgga agtagctcca acatcgggag aaattctgta
      181 tcctggtacc agcaggtccc aggaacggcc cccaaagtcc tcatctatga caataataag
      241 cgcccctcgg gggtttctga ccgattctct ggctccaagt ctggtacctc agcctccctg
      301 gccatcactg gactccaggc tggagatgag gctgtttatt actgcggagc atgggatagc
      361 agtctgagtg gttacatctt cggtgatggg acccggctca ccgtcctagg tcagcccaag
      421 gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01002354             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:5299:8000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002354
VERSION     KCWK01002354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:5299:8000"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68092.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          155 c          127 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctatgaaa atgataaacg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct gattcctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cttgagtgtt gtgttattcg
      421 gaggagggac ccgactgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002355             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:24218:5434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002355
VERSION     KCWK01002355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:24218:5434"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68093.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           89 a          143 c          127 g          102 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc catcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacagc cggccaggat cacctgctct ggagatgtat
      181 tgccaaaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtattggtca
      241 tctctgagga caccgaacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttactcagc agacagtagt ggtcatggct tcttcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002356             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:24686:12575
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002356
VERSION     KCWK01002356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24686:12575"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68094.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          164 c          118 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatattgg caataaaaac atgtactggt accagcagaa gccagggagc gctcccaagt
      241 tcttcctgta ctactactcc gactcagaca tgcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagccc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002357             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:14311:14896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002357
VERSION     KCWK01002357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:14311:14896"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68095.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          163 c          109 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gcagttacag catattctgg taccagcaga agccagggag tcctccccgg ttccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgatgatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002358             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:13485:18594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002358
VERSION     KCWK01002358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13485:18594"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68096.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          152 c          120 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgagctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctcct gctctggaag cagctccaat
      181 attggaagta attctgtata ctggtaccag cagttcccag gaacggcccc caaactcctc
      241 atctattata gtaatcagcg accctcaggg gtccctgacc gagtctctgg ctctaagtcg
      301 ggcacctcag tctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgacag cctgagaagt ccgctattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002359             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:11535:8389
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002359
VERSION     KCWK01002359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11535:8389"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68097.1"
                     /translation="DYHCQVYDGSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          160 c          124 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agtagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctacttctcc gactcagaca agcagttggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtatgacgg tagtgctgtt ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002360             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:13924:10518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002360
VERSION     KCWK01002360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13924:10518"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68098.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT          109 a          137 c          122 g           99 t
ORIGIN      
        1 acatgggggg ctgtggttct aggaggaaga gctctgggtg tctcaccatg acctggacca
       61 ctgttctgct cccctttctc actctctgca caggctctga ggcctcctat gacctgacac
      121 agccaccctc agtgtcagtg tccccaggac agacggccag gatcacctgc tctggagaaa
      181 tactggcaaa aaaatatact cagtggttcc agcagaagcc aggccagggc cctacactgg
      241 tgatatataa agacagtgag aggccctcag ggatccctga gcgattctct agctccagtt
      301 cagggacaac agttaccttg accatcagcg gggcccagac agaagatgag gctgactatt
      361 actgtcaatc agcagacaga agtcctaatc atgtgttttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002361             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:18496:10866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002361
VERSION     KCWK01002361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18496:10866"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..411
                     /note="immunoglobulin light chain variable region"
     V_region        81..411
     V_segment       81..372
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68099.1"
                     /translation="DYYCQSYDSDLRGVLF"
     J_segment       374..411
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           81 a          147 c          120 g          101 t
ORIGIN      
        1 acatggggag gacagtctcc agcatggcct ggtctcctct cctcctcacc cttctcattc
       61 actgcacagg gtcctgggcc cagtctgtgc tgacgcagcc gccctcagtg tctggggcgc
      121 ccgggcagag ggtcaccatc tcctgcactg ggagcaactc caacattgga ggttattatg
      181 tgcagtggta ccagcacctg ccaggaacgg cccccagact cctcatctat gaaaataata
      241 agcgaccctc aggggtttct gatcgattct ctggctccca gtctgggacc tcagcctccc
      301 tgaccatcac tggaccccag tctgaggatg aggctgatta ttactgccag tcctatgaca
      361 gcgacttgcg tggtgtgttg ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002362             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:12709:12470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002362
VERSION     KCWK01002362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12709:12470"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..385
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68100.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       387..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           88 a          147 c          121 g          106 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gcatctgggg cccccgggca gagggtcacc atctcctgca ctgggagcag ctccaacatc
      181 ggggcggatt tttatgtttc ctggtaccag cagttcccag gaacagcccc caaactcctc
      241 atctttgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggttcctcag cctccctgac catcactgga ctccaatctg aggatgaggc tgattattat
      361 tgttcatcat gggaaagcag cctgaattgg gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002363             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:15497:8417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002363
VERSION     KCWK01002363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15497:8417"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    69..410
                     /note="immunoglobulin light chain variable region"
     V_region        69..410
     V_segment       69..372
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <338..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68101.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       376..410
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>448
                     /gene="IGLC"
BASE COUNT           87 a          146 c          119 g           96 t
ORIGIN      
        1 acatgggggg gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctgactcagc caccctccct gtctgcatcc ccgggagcat cggccagact
      121 cccctgcacc ctgagcactg acctcagtgt tggtggtaaa aacatgtact ggtaccagca
      181 gaagccagga agcgctccca ggttattgct gtattaccac tccgactcag acaagcagct
      241 gggacctggg gtccccaatc gagtctctgg ctccaaggag acctcaagta acacagcgtt
      301 tttgctcatc tctgggctcc agcctgagga cgaggccgat tattactgtc aggtgtatga
      361 cagtagtgcc aacacgttat tcggaggagg gacccggctg accgtcctag gtcagcccaa
      421 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002364             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:14849:18533
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002364
VERSION     KCWK01002364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14849:18533"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..232
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68102.1"
                     /translation="DYYCQSYDVSLSAVLF"
     J_segment       236..269
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           63 a           90 c           78 g           76 t
ORIGIN      
        1 acatgggggg agcagctcca acattggagg ttattatgta tactggtacc agcagttccc
       61 aggaatggcc cccaaactcc tcatctatga caataataag cgaccctcag gggtttctga
      121 ccgattctct ggctccaagt ctggtacctc agcctccctg accatcgctg ggctccagac
      181 tgaggatgag gctgattatt attgccagtc ctatgacgtc agtctgagtg ctgttttatt
      241 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01002365             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:10911:8115
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002365
VERSION     KCWK01002365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10911:8115"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..434
                     /note="immunoglobulin light chain variable region"
     V_region        110..434
     V_segment       110..385
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68103.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          151 c          134 g           97 t
ORIGIN      
        1 acatgggggc cctgtctggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggcc tcctcgctca ctgcacaggc tctgcgacct cctttgagct
      121 gactcagcca ccctcggtgt cagcggcctc aggacagacg gccaggatca cctgtggggg
      181 agacaacatt ggaattaaat ttgtccactg gtaccagcag aagccagcgc aggcccctgt
      241 gaaggtcatc tatgctgatg acaaacggcc ctcagggatc cctgagagat tctctggctc
      301 caattcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga
      361 ctattcctgt caggtgtggg acagtgagac tgatcattac atcttcggtg ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002366             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:14320:20894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002366
VERSION     KCWK01002366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14320:20894"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..442
                     /note="immunoglobulin light chain variable region"
     V_region        118..442
     V_segment       118..405
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68104.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT          112 a          138 c          129 g          101 t
ORIGIN      
        1 acatggggca gagtacatgg gggctgtggt tctaggagga agagctctgg gtgtctcacc
       61 atgacctgga ccactgttct gctccccttt ctcactctct gcacaggctc tgaggcctcc
      121 tatgacctga cacagccacc ctcagtgtca gtgtccccag ggcagacggc caggatcacc
      181 tgctctggag aaatactggc aaaaaaatat actcagtggt tccagcagaa gtcaggccag
      241 ggccctagac tggtgatata taaagacagt gagaggccct cagggatccc tgagcgattc
      301 tctagctcca gttcagggac aacagtcacc ttgaccatca gcggggccca gacagaagat
      361 gaggctgact attactgtca atcagcagac agaagtccta atcatgtgtt tttcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002367             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:19932:16206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002367
VERSION     KCWK01002367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19932:16206"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..278
                     /note="immunoglobulin light chain variable region"
     V_region        5..278
     V_segment       5..238
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <206..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68105.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       241..278
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>316
                     /gene="IGLC"
BASE COUNT           70 a           93 c           84 g           69 t
ORIGIN      
        1 acatgggggc atcaatgttg ctggctacca catacactgg taccagcaga agccagggag
       61 tcctccccga tatcttctga gatacaaatc ggactcagat aagggccagg gctctggagt
      121 ccccagccgc ttctctggat ccaaagatgc ttcagggaac acagggattt tacgcatctc
      181 tggactccag tctgaggatg aggctgacta ttactgtgcc atcggacaca gcagcggtga
      241 ttacatcttc ggtgctggga cccggctcag cgtcctaggt cagcccaagg cttcccccac
      301 ggtcactctg ttcccg
//
LOCUS       KCWK01002368             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:23810:10948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002368
VERSION     KCWK01002368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23810:10948"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..258
                     /note="immunoglobulin light chain variable region"
     V_region        8..258
     V_segment       8..221
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <177..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68106.1"
                     /translation="DYWCAAGYGSGSTWQWVF"
     J_segment       222..258
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           58 a           89 c           93 g           56 t
ORIGIN      
        1 acatgggggg gaatgtatat gcttcctggt accagcagaa gccaggccag gcccctgtac
       61 tggtcatcta caaagatacc aaccggccct cagggattcc tcagcgattc tctggctcca
      121 actcagggga cacggccacc ctgaccatca gcagggtcga ggctggggat gaggccgact
      181 attggtgtgc tgcaggctat ggcagtggga gcacctggca gtgggtattc ggcggaggga
      241 cccggctaag cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002369             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22074:19206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002369
VERSION     KCWK01002369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22074:19206"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68107.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          140 c          137 g          103 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggatcc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002370             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:13494:13516
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002370
VERSION     KCWK01002370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13494:13516"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..380
                     /note="immunoglobulin light chain variable region"
     V_region        87..380
     V_segment       87..343
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>352
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68108.1"
                     /translation="DYHCQVWDINSHHLLF"
     J_segment       345..380
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        381..>418
                     /gene="IGLC"
BASE COUNT           81 a          126 c          125 g           86 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagt gtccccagga cagacggcca ggatcacctg
      121 tgggggagac aacattggaa gtgaagttgt gaactggtac caacagaagc caccgctggc
      181 ccctgtgttg gtcatctatg ctgatagcga ccggccctca gggatccctg agcgattctc
      241 tggctccaaa tcagggacca cggccaccct gagcatcagc ggggtcgagg ccggggatga
      301 ggctgactat cactgtcagg tgtgggacat taatagccat catctgttat tcggaggagg
      361 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002371             295 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:13081:2692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002371
VERSION     KCWK01002371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 295)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:13081:2692"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..257
                     /note="immunoglobulin light chain variable region"
     V_region        8..257
     V_segment       8..218
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <185..>229
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68109.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       220..257
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>295
                     /gene="IGLC"
BASE COUNT           63 a           86 c           73 g           73 t
ORIGIN      
        1 acatgggagg atattctggt accaccagaa gccagggagt cctccccggt atcttctgaa
       61 ctaccacaca gactcagata ttcatcaggg ctctggagtc cccagccgct tctctggatc
      121 caaagatgct tcggccaatg cagggatttt actcatctct ggactccagt ctgaggatga
      181 ggctgactat tactgtatga tttggcacaa caatgcttat tgggttttcg gcggagggac
      241 ccggctaacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002372             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:23015:17286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002372
VERSION     KCWK01002372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:23015:17286"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68110.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          155 c          119 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaccg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002373             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:17884:15380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002373
VERSION     KCWK01002373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17884:15380"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68111.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          149 c          137 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta aatatgtcca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
      241 atctatgctg atagcagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggagcaccg ccaccctgac catcagcggg gtcgaggccg ggtatgaggc tgactatttc
      361 tgtcaggtgt gggacgatag tagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002374             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:12348:14881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002374
VERSION     KCWK01002374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12348:14881"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68112.1"
                     /translation="DYYCQVWGMTSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          142 c          138 g           95 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgagtcag
      121 ccaccctcgg tgtcagtgtc cccaggagag acggccagga tcacctgtgg cggacacaaa
      181 attggaagtg aagtagtgaa ttggtaccag cagaagccac cgcaggcccc tgtgctggtc
      241 atctatgctg ataacgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt ggggcatgac tagtgatcat ccggtattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002375             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:13502:8728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002375
VERSION     KCWK01002375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13502:8728"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..303
                     /note="immunoglobulin light chain variable region"
     V_region        8..303
     V_segment       8..266
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68113.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       267..303
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           74 a          108 c           82 g           77 t
ORIGIN      
        1 acatgggcag tctcacatgc accttcagcg gtggcatcaa tgttgctgcc taccacatac
       61 actggtacca gcagaagcca gggagtcccc cccggtatct tctgagttac aaatcagact
      121 cagataaggg ccagggctct ggagtcccca gccgcttctc tggatccaaa aatgcttcaa
      181 cgaacacagg cattttacac atctctgggc tccagtctga ggatgaggct gactatttct
      241 gtgccattgg acacagcagc ggtccttaca tcttcggtgc tgggacccgg ctcaccgtcc
      301 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01002376             406 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:5238:9231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002376
VERSION     KCWK01002376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 406)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5238:9231"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    41..368
                     /note="immunoglobulin light chain variable region"
     V_region        41..368
     V_segment       41..328
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <290..>340
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68114.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       332..368
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        369..>406
                     /gene="IGLC"
BASE COUNT           82 a          122 c          115 g           87 t
ORIGIN      
        1 acatgggggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
       61 accctcggtg tcagtgtccc ccggacagac ggccaggatc acctgtggag gagacaacat
      121 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tgctggtcat
      181 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      241 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      301 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccgactgac
      361 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002377             364 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:24666:13690
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002377
VERSION     KCWK01002377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 364)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:24666:13690"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..326
                     /note="immunoglobulin light chain variable region"
     V_region        8..326
     V_segment       8..287
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <254..>298
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68115.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       292..326
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        327..>364
                     /gene="IGLC"
BASE COUNT           75 a          111 c           90 g           88 t
ORIGIN      
        1 acatgggtca gcatctccgg gagcatcagt cagactcagc tgcaccttga gcagtggcat
       61 caatgttggt tcttacacca tattctggta ccagcagaag ccagggagtc ctccccggtt
      121 ccttctgtac tactactcag actcaaataa tcaccagggc tctggagtcc ccagccgctt
      181 ctctggatcc aaagatgctt cagccaatgc agggctttta ctgatctctg ggctccagtc
      241 tgaagatgag gctgactatt actgtgccat gtggcacagc agcgcttatg ccttattcgg
      301 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      361 cccg
//
LOCUS       KCWK01002378             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:17221:17286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002378
VERSION     KCWK01002378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17221:17286"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68116.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          161 c          119 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctata ctactacttc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002379             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:19965:6568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002379
VERSION     KCWK01002379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19965:6568"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68117.1"
                     /translation="DYYCQVYDSGANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          164 c          124 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagcgttgg tagtaaaaat atgtactggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacag tggtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002380             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:12998:10833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002380
VERSION     KCWK01002380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12998:10833"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68118.1"
                     /translation="DYYCSAWDSSLTGGFF"
     J_segment       406..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           97 a          154 c          123 g          107 t
ORIGIN      
        1 acatggggag cttcagctgt ggctagagaa gacaggactc aggacaatct ccagcatggc
       61 ctgcttccct ctcatcctca ccgtcctcac tcactgtgca ggatcctggg cccagtctgt
      121 gctgactcaa ccaccctcag cgtctggggc ccccgggcag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaatta tgtatactgg taccagcagt tctcagggaa
      241 ggcccccaaa ctcctcatcc ataataataa tcagcgaccc tcaggggtcc ctgatcgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggacatc agtgggctcc agtccgagga
      361 tgaggctgat tattactgct cagcatggga tagcagtctg accggtggct ttttcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01002381             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:7203:5886
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002381
VERSION     KCWK01002381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7203:5886"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..268
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68119.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       270..306
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           75 a          103 c           99 g           67 t
ORIGIN      
        1 acatgggggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
       61 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gtactggtca
      121 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      181 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      241 gtcaggtgtg ggacacaact attgatcacg gcttattcgg aggagggacc cggctgaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002382             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:4000:11522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002382
VERSION     KCWK01002382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:4000:11522"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68120.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          153 c          121 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggccacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002383             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:18595:17552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002383
VERSION     KCWK01002383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18595:17552"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..271
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <233..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68121.1"
                     /translation="DYYCASYEGSNTFLF"
     J_segment       275..305
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           73 a          107 c           87 g           76 t
ORIGIN      
        1 acatgggggg tctcctggac agtcggtcac catctcctgc agtggaacca gcagtaagat
       61 tgggtatcac aatgctgtgt cctggtacca agagcatcca ggcaaagccc ccaaactcat
      121 gatttatgac gtcaataagc ggcccacagg gatctctgat cgcttctctg gctccaagtc
      181 tggcgacacg gcctccctga ccatctctgg gctccaggct gatgatgaag ctgattatta
      241 ctgcgcctca tatgaaggca gcaacacttt cctcttcgga ggagggaccc ggctgaccgt
      301 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002384             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:10326:19990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002384
VERSION     KCWK01002384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:10326:19990"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68122.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          162 c          109 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagtc tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002385             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:8569:7618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002385
VERSION     KCWK01002385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:8569:7618"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68123.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          100 a          137 c          124 g          105 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg aggtgacaca
      121 gtcaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagcaat
      181 actggcaaat aattatgctc agtggttcca gcagaagcct gaccaggccc ctgtgttggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gttgacagca gtgcccatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002386             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:17871:15652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002386
VERSION     KCWK01002386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17871:15652"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68124.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          163 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccactcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002387             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:11974:14386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002387
VERSION     KCWK01002387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11974:14386"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..420
                     /note="immunoglobulin light chain variable region"
     V_region        90..420
     V_segment       90..383
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <345..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68125.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       384..420
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           89 a          151 c          117 g          101 t
ORIGIN      
        1 acatgggggc aggactcagg acaatctcca gcatggcctg gttccctctc gtcctcaccc
       61 tcctcactca ctgtgcaggg tcctgggccc agtctgtgct gactcagact ccctcagcgt
      121 ctgaggccgc caggaagagt gtcaccatct cctgttctgg aagcagctcc aacatcggaa
      181 gaaatagtgt atcctggtac cagcagctcc caggaacagc tcccaaactc ctcatctatt
      241 atagtgatca acgagcctca ggtgtctctg accgattctc tggctccaag tctggcacgt
      301 cagcctccct ggccatcagc gggctccagg ccgaggatga ggctgattat tactgcgcag
      361 catgggatga tagcctgagc ggttacatct tcggtgctgg gacccggctc accgtcctag
      421 gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01002388             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:14852:15660
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002388
VERSION     KCWK01002388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14852:15660"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..261
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <233..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68126.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       268..305
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           69 a          104 c           84 g           86 t
ORIGIN      
        1 acatgggggg tctcctgggc agtcggtcac catctcctgc actggaacca gcagtgatat
       61 tgggtcttat aatgctgtgt cttggtacca acaacatcca ggcaaagccc cccaactcat
      121 aatttttgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg gctccaagtc
      181 tggcaacacg gcctccctga ccatttctgg gctccaggct gaggatgagg ctgattatta
      241 ctgctgctca tatgtaggca gcaacactta catcttcgat gttgggaccc ggctcaccgt
      301 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002389             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:13941:12671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002389
VERSION     KCWK01002389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13941:12671"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68127.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           98 a          151 c          113 g          117 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttggtaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcatc aggggtctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002390             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:13516:5799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002390
VERSION     KCWK01002390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13516:5799"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68128.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>430
                     /gene="IGLC"
BASE COUNT           85 a          127 c          133 g           85 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccagcg cacgcccctg tgctggtcat
      241 ctatgctaat agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg ggtgaggctg actattactg
      361 tcaggtgtgg gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag
//
LOCUS       KCWK01002391             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:5166:13784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002391
VERSION     KCWK01002391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5166:13784"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..399
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68129.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       401..436
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           95 a          152 c          117 g          110 t
ORIGIN      
        1 acatggggag ctctggagcc agggatccct tccaatatca gcaccatggc ctggactctg
       61 ctcctcctcc agttcctcct cacttgctgc ccagggtcca attctcaggc tgtagtgact
      121 caggagccct caatgactgt gtccccagga gggacagtca ctctcacctg tgcttccagc
      181 actggagcag tcaccagtgg tcactctcca cactggttcc agcagaaacc tggacaagcc
      241 cccaagacac tgatttataa tacaaactac agacactcct ggactcctgc ccggttctca
      301 ggctccctcc ttgggggtaa agctgccctg acactgtcag gtgcgcagcc tgaggatgag
      361 gctgagtatt attgtttact gtactatagt ggtgctcagc tgttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002392             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:10180:14644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002392
VERSION     KCWK01002392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10180:14644"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68130.1"
                     /translation="DYFCAAWDDSLTGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           94 a          157 c          120 g          110 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcctcctca ccctcctcac tcactgtgca gggtccaggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaaccagc tccaacatcg gaagtaatag tgtatcctgg taccagcagc tcccagaaac
      241 gtctcccaaa ctcctcatct attataatga tcggcgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tatttctgcg cagcatggga tgatagcctg accggttaca ttttcggtac
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01002393             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:20262:18367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002393
VERSION     KCWK01002393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20262:18367"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68131.1"
                     /translation="DYYCQVWDSTSDHVFF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          141 c          136 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 gccctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacgacat
      181 tggaagtaaa tatgtgcact ggtaccagca gaagccaccg caggcccctg tgctggtcat
      241 ctattatgat tgcgaacggc cctcagggat ccctgagcga ttctctgact ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtacta gtgatcatgt gtttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002394             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:13157:12607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002394
VERSION     KCWK01002394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13157:12607"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68132.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       395..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          151 c          122 g          108 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctcctct
       61 cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc tgacgcagcc
      121 gccctcagtg tctggggcgc ccgggcagag ggtctccatc tcctgcactg ggagcagctc
      181 caacattgga gatttttatg tgcagtggta ccagcacctt ccaggaacgg cccccaaact
      241 cctcatctat gaaaataata agcgaccctc aggggtttct gatcgattct ctggctccca
      301 gtctggaacc tcagcctccc tgaccatcac tggactccag tctgaggatg aggctgatta
      361 ttactgccag tcctatgaca gcagtttgat tgctgtgtta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002395             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:17832:7637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002395
VERSION     KCWK01002395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:17832:7637"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68133.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          158 c          118 g          113 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ccctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcaag ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtctt ataatgctgt gtcttggtac caacagcgtc caggcaaagc
      241 cccccaactc ataatttttg aggtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgctgct catatgtagg cagcaacact tacatcttcg atgttgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002396             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10571:10336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002396
VERSION     KCWK01002396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10571:10336"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68134.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          160 c          116 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 ctgcatctcc tggagcatcg gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatacaaatc agactcagat aaggaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ctcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ctactgtgcc attgggcaca gcagcggtga ttacattttc gctgctggga
      421 cccgcctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002397             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13947:5965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002397
VERSION     KCWK01002397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13947:5965"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68135.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       399..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>449
                     /gene="IGLC"
BASE COUNT           83 a          146 c          118 g          102 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa cagcatccag gcacagcccc
      241 caaagtcatg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat atacaggcat caacagttac atcttcggtg gtgggacccg
      421 gctcaccgtc ctaggtcact ctgttcccg
//
LOCUS       KCWK01002398             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:19699:6523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002398
VERSION     KCWK01002398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19699:6523"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68136.1"
                     /translation="DYHCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           97 a          162 c          113 g          104 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gtcagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgactacca cacacactgg taccaacaga agccagggag tcccccccga tatcttctga
      241 aatacaaatc agacacagac cagggccagg ggtctggagt ccccagccgc ttctctggat
      301 ccaaagatcc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta tcactgtgcc attggtcaca gcagcggtcc atacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002399             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:12096:2838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002399
VERSION     KCWK01002399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12096:2838"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68137.1"
                     /translation="DYYCCSYTTSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           90 a          154 c          117 g          112 t
ORIGIN      
        1 acatgggggg gggtctcaga aggcagcgct ctcaggacgt ctccaccatg gcctggactc
       61 tgctcctcgt caccctcctc actcaaggca caggatcctg ggctcagtct gccccgactc
      121 agcctccctc tatgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 ccagtgacat tggtggttat aattatgtct cctggtacca gcagcaccca gacaaagccc
      241 ccaaactcat aatttatggt gtcagaaatc ggccctcagg ggtctcttat cgcttctctg
      301 gctccaagtc tggtaatacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgttgttca tatacaacca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002400             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:22513:13384
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002400
VERSION     KCWK01002400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22513:13384"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..258
                     /note="immunoglobulin light chain variable region"
     V_region        8..258
     V_segment       8..221
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <183..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68138.1"
                     /translation="DYSCQVWDSSSDHYIF"
     J_segment       222..258
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           63 a           90 c           82 g           61 t
ORIGIN      
        1 acatgggcaa tattggaatt acatatgtga actggtacca gcagaagcca gcgcaggccc
       61 ctgtgcaggt catctatgct gataccaaac ggccctcagg gatccctgag cgattctctg
      121 gctccaactc agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg
      181 ctgactattc ctgtcaggtg tgggacagca gtagtgatca ttacatcttc ggtgctggga
      241 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002401             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:9524:4265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002401
VERSION     KCWK01002401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9524:4265"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68139.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>460
                     /gene="IGLC"
BASE COUNT           94 a          143 c          123 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaagatc acctgctctg tagatgcact
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 cgatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002402             389 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17419:9236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002402
VERSION     KCWK01002402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 389)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 389)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..389
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17419:9236"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    30..351
                     /note="immunoglobulin light chain variable region"
     V_region        30..351
     V_segment       30..315
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <279..>323
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68140.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       319..351
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        352..>389
                     /gene="IGLC"
BASE COUNT           85 a          116 c          111 g           77 t
ORIGIN      
        1 acatgggtta ctgcacaggc tctgcgacct cctatgaact gactcagtca ccctcagtgt
       61 cagcggcctc aggacagccg gccaggatca cctgtggggg agacaacatt ggaactaaaa
      121 ctgtgcactg gtaccagcag aagccaccgc agggccctgt attggtcatc tttgctgata
      181 gtaaacggcc ctcagggatc cctgagcgat tctctggctc caactcaggg aacaccgcca
      241 ccctgaccat cagcagggtc gaggccgggg atgaggctga ctattactgt caggtgtggg
      301 acagtagtag taaatggata ttcggcgggg ggacccggct aaccgtccta ggtcagccca
      361 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002403             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:23487:12072
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002403
VERSION     KCWK01002403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:23487:12072"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68141.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       398..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          156 c          115 g          115 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaagct gccccgactc
      121 agcctccctc tgtgtccggg tctcctgggc agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtcttat aatgctgtgt cttggtacca acaacatcca ggcaaagccc
      241 cccaactcat aatttttgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatttctgg gctccaggct gaggatgagg
      361 ctgattatta ctgctgctca tatgtaggca gcaacactta catcttcgat gttgggaccc
      421 ggctcaccgt cctagctcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002404             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:21140:10324
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002404
VERSION     KCWK01002404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21140:10324"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68142.1"
                     /translation="VYYCGAWDSSLSGYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          155 c          124 g          108 t
ORIGIN      
        1 acatgggggc ctcagctgtg agcacagaag gcaggacttg ggacaatctt catcatgacc
       61 tggtcccctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctacggcc ccagggcaga aggtcaccat ctcctgctct
      181 ggaagtagct ccaacatcgg gagaaattct gtatcctggt accagcaggt cccaggaacg
      241 gcccccaaag tcctcatcta tgacaataat aagcgcccct cgggggtttc tgaccgattc
      301 tctggctcca agtctggtac ctcagcctcc ctggccatca ctggactcca ggctggagat
      361 gaggctgttt attactgcgg agcatgggat agcagtctga gtggttacat cttcggtgat
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002405             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:6823:10807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002405
VERSION     KCWK01002405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:6823:10807"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68143.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          162 c          111 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcttc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catcttctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002406             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17148:19580
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002406
VERSION     KCWK01002406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17148:19580"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..388
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68144.1"
                     /translation="DYYCAAWDDSLRSYIF"
     J_segment       392..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           93 a          152 c          119 g          103 t
ORIGIN      
        1 acatgggggt acagaaggca ggactcagga caatctccag catggcctgg ttccctctcg
       61 tcctcaccct cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagcctc
      121 cctcagcgtc tgaggccgcc aggaagagtg tcaccatctc ctgttctgga agcagctcca
      181 acatcggaag taataatgtg tcctggtacc agcacctccc aggaacagct cccaaactcc
      241 tcatctacta taatgatcaa cgaggctcag gtgtctctga ccgattctct ggctccaagt
      301 ctggcacgtc agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt
      361 actgcgcagc gtgggatgat agcctgagga gttacatctt cgctgctggg acccgggtca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01002407             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:18449:6267
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002407
VERSION     KCWK01002407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18449:6267"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68145.1"
                     /translation="AYYCQLWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          143 c          132 g          103 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagc ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagactacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg cctattattg
      361 tcagctgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002408             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:11032:3567
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002408
VERSION     KCWK01002408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11032:3567"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..400
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68146.1"
                     /translation="DYSCCSYRSGNTWLF"
     J_segment       401..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           81 a          158 c          127 g          108 t
ORIGIN      
        1 acatggggct ggggtctcag gaggcagcgc tctcgggacg tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcagtc tgccctgact
      121 cagcctccct cagtgtccaa gtctcttgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgaca ttggtggtta tgatggcgtc tcctggtacc agcagcactc agggacagcc
      241 cccagactcc tgatttatga tgtcactaag cggccctcag gggtctcgga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctc accatctctg ggctccagac tgaggacgag
      361 gctgattatt cttgttgctc atataggagt ggaaacactt ggctattcgg cggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002409             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:11786:15787
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002409
VERSION     KCWK01002409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11786:15787"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68147.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          154 c          129 g          112 t
ORIGIN      
        1 acatgggggc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac catctcctgc
      181 actgggagca gctccaacat tggaggttat tatgtgcagt ggtaccagca gcttccagga
      241 gcggccccca aactcctcat ctatgaaaat gataaacgac cctcaggggt ttctgatcga
      301 ttctctggct cccagtctga ttcctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagcagct tgagtgttgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002410             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:9241:5973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002410
VERSION     KCWK01002410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:9241:5973"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68148.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          158 c          126 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtc cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaggca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctggccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002411             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:15910:7597
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002411
VERSION     KCWK01002411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15910:7597"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..388
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68149.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          148 c          119 g          108 t
ORIGIN      
        1 acatggggac aggaggcaac actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc acgatctcct gcagtgggag caactccaac
      181 attggatatt attatgtgca gtggtaccag cagcttccag gaacggcccc caaactcctc
      241 atctatgaaa ataataagcg accctctggg gtttctgatc gattctctgg ctcccagtct
      301 ggtacctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgccactcct atgacagcag tttgagtggt gtcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002412             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:21821:10716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002412
VERSION     KCWK01002412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21821:10716"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..404
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68150.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       406..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           86 a          161 c          121 g          113 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt agtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggttcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgat gccgattatt tctgccaggt gtttgacagt agtgttgtgt tcttcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01002413             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:17178:17052
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002413
VERSION     KCWK01002413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:17178:17052"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    67..397
                     /note="immunoglobulin light chain variable region"
     V_region        67..397
     V_segment       67..360
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <328..>369
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68151.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       361..397
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        398..>435
                     /gene="IGLC"
BASE COUNT           75 a          153 c          111 g           96 t
ORIGIN      
        1 acatggggga ccccaatcct cctcctcctc ctcactctcc tccttcactg cacagggtct
       61 ctctcccagc ctgtgctgac tcagtcgccc tctgcctctg cctccctggg agcctcggtc
      121 aagctcacct gcactctgag cagtggccac tacagctaca ccatcgcatg gcatcagcag
      181 cagcaaggga aggcccctcg gttcttgatg tggcttaaga gtgatggcag ccacaccaag
      241 gggggggtcc ctgatcgctt ctcaggctcc agctccgggg ctgagcgcta cctcaccatc
      301 tccaacctcc agtctgagga tgaggctgat tattactgtc agacctggga tattggcatt
      361 tgggtattcg gcggagggac ccggctaacc gtcctaggtc agcccaaggc tgccccctcg
      421 gtcactctct tcccg
//
LOCUS       KCWK01002414             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:9118:9503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002414
VERSION     KCWK01002414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9118:9503"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68152.1"
                     /translation="DYYCSSYGGSNNLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          151 c          122 g          112 t
ORIGIN      
        1 acatgggggc ttggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc agcatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatggagg cagcaataat ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002415             353 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:17160:17386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002415
VERSION     KCWK01002415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 353)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17160:17386"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..315
                     /note="immunoglobulin light chain variable region"
     V_region        112..315
     V_segment       112..276
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <240..>287
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68153.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       278..315
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        316..>353
                     /gene="IGLC"
BASE COUNT           66 a          116 c           86 g           85 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcggccccca
      121 aactcctcat ctatgaaaat aataagcgac cctcaggggt ttctgatcga ttctctggct
      181 cccagtctgg tacctcagcc tccctgacca tcactggact ccagtctgac gatgaggctg
      241 attattactg tcagtcctat gatagcagcc tgagtgttgt gttattcgga ggagggaccc
      301 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002416             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:10713:3642
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002416
VERSION     KCWK01002416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10713:3642"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68154.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          154 c          120 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca gtggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcgtccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcgtctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaagc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcggac gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002417             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:10407:18792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002417
VERSION     KCWK01002417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10407:18792"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68155.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       413..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           91 a          154 c          129 g          114 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag gttattatgt gcagtggtac cagcagcttc
      241 caggaacggc ccccaaactc ctcatctatg aaaatgataa acgaccctca ggggtttctg
      301 atcgattctc tggctcccag tctgattcct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagcttgagt gttgtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgtcccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01002418             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:4743:12392
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002418
VERSION     KCWK01002418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:4743:12392"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68156.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcaaccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002419             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:10015:3521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002419
VERSION     KCWK01002419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10015:3521"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68157.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          163 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctata ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactacca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002420             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:12627:14142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002420
VERSION     KCWK01002420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12627:14142"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68158.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          147 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtatacact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002421             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:21225:12343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002421
VERSION     KCWK01002421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21225:12343"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68159.1"
                     /translation="DYHCQVFDSSDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          161 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tgataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 ttttcctgta ctacttctcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaagagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtttgacag tagtgatgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002422             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:11969:4142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002422
VERSION     KCWK01002422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11969:4142"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..403
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68160.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       408..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          161 c          112 g          114 t
ORIGIN      
        1 acatggggca ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagtcaga ctcagctgca ccttgagcag tggcatcaat
      181 gttggttctt acaccatatt ctggtaccag cagaagccag ggagtcctcc ccggttcctt
      241 ctgtactact actcagactc aaataatcac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc caatgcaggg cttttactga tctctggact ccagtctgaa
      361 gatgaggctg actattactg tgccatgtgg cacagcagcg cttatgcctt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002423             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:20948:17730
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002423
VERSION     KCWK01002423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20948:17730"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68161.1"
                     /translation="DYYCCSRSSSSTYVF"
     J_segment       399..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           82 a          161 c          117 g          112 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacgtt ggtggttata actctgtctc ctggtaccaa caacacccag gcaaagcccc
      241 caaagtcatg atttttggtg tcaataatcg gccctctggg gtctctgacc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagtctg aggacgaggc
      361 tgattattac tgttgttcac gttcaagcag cagcacttac gtcttcggtc ctgggacccg
      421 gctcaccgtc ctgggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002424             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:13470:3947
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002424
VERSION     KCWK01002424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:13470:3947"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68162.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          101 a          136 c          123 g          103 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagg tgacacagtc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagcaatact
      181 ggcaaataat tatgctcagt ggttccagca gaagccagac caggcccctg tgttggtgat
      241 atataaagac actgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacagtt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagtt gacagcagtg cccatcatcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002425             394 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:19508:2899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002425
VERSION     KCWK01002425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 394)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19508:2899"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..356
                     /note="immunoglobulin light chain variable region"
     V_region        23..356
     V_segment       23..319
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <287..>328
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68163.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       320..356
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        357..>394
                     /gene="IGLC"
BASE COUNT           71 a          129 c          110 g           84 t
ORIGIN      
        1 acatgggaca gggtctctct cccagcctgt gctgactcag tcgccctctg cctctgcgtc
       61 cctgggagcc tcggtcaagc tcacctgcac tctgagcagt ggccactaca gctacaccat
      121 cgcatggcat cagcagcagc aagggaaggc ccctcggttc ttgatgtggc ttaagagtga
      181 tggcagccac accaaggggg acggggtccc tgatcgcttc tcaggctcca gctccggggc
      241 tgagcgctac ctcaccatct ccaacctcca gtctgaggat gaggctgatt attactgtca
      301 gacctgggat attggcattt gggtattcgg cggagggacc cggctaaccg tcctaggtca
      361 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002426             453 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:7277:19364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002426
VERSION     KCWK01002426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 453)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7277:19364"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..379
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <343..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68164.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       383..415
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>453
                     /gene="IGLC"
BASE COUNT           92 a          143 c          129 g           89 t
ORIGIN      
        1 acatgggcag gaggcagcat tgacggtgcc tcagccatgg cctggaccct tctcctcctc
       61 ggcctcctcg cttactgcac aggctctgcg acctcctatg aactgactca gtcaccctca
      121 gtgtcagcgg cctcaggaca gccggccagg atcacctgtg ggggagacaa cattggaact
      181 aaaactgtgc actggtacca gcagaagcca ccgcagggcc ctgtattggt catctttgct
      241 gacagtaaac ggccctcagg gatccctgag cgattctctg gctccaactc agggaacacc
      301 gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta ctgtcaggtg
      361 tgggacagta gtagtaaatg gatattcggc ggggggaccc ggctaaccgt cctaggtcag
      421 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002427             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:12553:9643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002427
VERSION     KCWK01002427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12553:9643"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68165.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       399..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           82 a          162 c          114 g          114 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccac
      181 cagtgacgtt ggtggttcta attctgtctc ctggtaccaa caacacccag gcaaagcccc
      241 caaagtcatg atttttggtg tcaataatcg gccctctggg gtctctgacc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagtctg aggacgaggc
      361 tgattattac tgttgttcac attcaaccag tagcacttac gtcttcggtc ctgggacccg
      421 gctcaccgtc ctgggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002428             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:12678:11845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002428
VERSION     KCWK01002428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12678:11845"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68166.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          151 c          116 g          107 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagctcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002429             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:10991:9709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002429
VERSION     KCWK01002429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:10991:9709"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68167.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       399..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           83 a          164 c          112 g          113 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccac
      181 cagtgacgtt ggtggttcta actctgtctc ctggtaccaa caacacccag acaaagcccc
      241 caaactcatg atttttggtg tcaataatcg gccctctggg gtctctgacc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagtctg aggacgaggc
      361 tgattattac tgttgttcac attcaaccag tagcacttac gtcttcggtc ctgggacccg
      421 gctcaccgtc ctgggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002430             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11177:11108
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002430
VERSION     KCWK01002430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11177:11108"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68168.1"
                     /translation="DYHCQVWDLNSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          143 c          135 g          100 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctcactcag
      121 ccaccctcga tttcagtgtc cccaggacag acgaccaggg tcacctgtgg gggagacaac
      181 attgggagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atctatgctg atagcgagcg gccctcaggg atccctgaac ggttctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactatcac
      361 tgtcaggtgt gggaccttaa tagtcatcat ttgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002431             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17186:7979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002431
VERSION     KCWK01002431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17186:7979"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..376
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68169.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       388..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          144 c          131 g           97 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctttgagt tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaattaaa tttgtccact ggtaccagca gaagccagcg caggcccctg tgaaggtcat
      241 ctatgctgat gacaaacggc cctcagggat ccctgagaga ttctctggct ccaattcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg attattcctg
      361 tcaggtgtgg gacagtgaga ctgattatta catcttcggt actgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002432             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:13827:9869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002432
VERSION     KCWK01002432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13827:9869"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68170.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       215..251
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           60 a           86 c           71 g           72 t
ORIGIN      
        1 acatggggga gattattttg tgcagtggta ccagcacctt ccaggaacgg cccccaaact
       61 cctcatctat gaaaataata agcggccctc agggatttct gatcgattct ctggctccca
      121 gtctggaacc tcagcctccc tgaccatcac tggactccag tctgaggatg aggctgatta
      181 ttactgccag tcctatgaca gcagtttgat tgctgtgtta ttcggaggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002433             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:10280:13695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002433
VERSION     KCWK01002433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10280:13695"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..257
                     /note="immunoglobulin light chain variable region"
     V_region        8..257
     V_segment       8..220
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <183..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68171.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       222..257
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>296
                     /gene="IGLC"
BASE COUNT           65 a           90 c           80 g           61 t
ORIGIN      
        1 acatgggcaa cattggaagt caaagtgtgc actggtacca gcacaagcca ccgcaggccc
       61 ctgttctggt catcttttat tataccgaac ggccctcagg aatccctgag cgaatctctg
      121 gctccaaatc agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg
      181 ctgactatta ctgtcaggtg tgggacacaa gtcttgatca cggcttattt ggaggaggga
      241 cccggctgac cgtcctaagt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002434             366 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17146:17326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002434
VERSION     KCWK01002434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 366)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17146:17326"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..328
                     /note="immunoglobulin light chain variable region"
     V_region        126..328
     V_segment       126..291
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <256..>300
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68172.1"
                     /translation="DYYCQVYDSTANVLF"
     J_segment       292..328
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        329..>366
                     /gene="IGLC"
BASE COUNT           63 a          126 c           92 g           85 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgg tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt actactactc cgactcagac aagcagctgg gacctggggt ccccactcga
      181 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tggactccag
      241 cccgaggacg aggccgatta ttactgtcag gtgtatgaca gtactgctaa tgtgttattc
      301 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      361 ttcccg
//
LOCUS       KCWK01002435             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:15175:10911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002435
VERSION     KCWK01002435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15175:10911"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    174..366
                     /note="immunoglobulin light chain variable region"
     V_region        174..366
     V_segment       174..327
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <291..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68173.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       329..366
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>404
                     /gene="IGLC"
BASE COUNT           68 a          131 c          107 g           98 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac catctcctca
      181 tctatgaaaa tgataaacga ccctcagggg tttctgatcg attctctggc tcccagtctg
      241 attcctcagc ctccctgacc gtcactggtc tccagtctga ggatgaggct gattattact
      301 gccagtccta tgacagcagc ttgagtgttg tgttattcgg aggagggacc cggctgaccg
      361 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002436             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:21939:3765
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002436
VERSION     KCWK01002436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21939:3765"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68174.1"
                     /translation="DYYCQVWDISSDHPVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          143 c          134 g          101 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacagcc tctgcggcct cctatgctct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggagg agacaacctt
      181 ggatatgaag ttgtcaactg gtaccagcag aagccaccgc aggcccctgt ggtggtcatc
      241 tatgctgatt atgaacggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacacggcca ccctgaccat cagcggagtc gtggccgggg atgaggctga ctattattgt
      361 caggtgtggg acattagtag tgaccatccg gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002437             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:12710:21035
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002437
VERSION     KCWK01002437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12710:21035"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68175.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          101 a          138 c          123 g          104 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctggg gcctcctatg aggtgacaca
      121 gtcaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagcaat
      181 actggcaaat aattatgctc agtggttcca gcagaagcca gaccaggccc ctgtgttggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgac cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gttgacagca gtgcccatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002438             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:20628:3132
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002438
VERSION     KCWK01002438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20628:3132"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68176.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           89 a          159 c          119 g          107 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttga gcagtggcgt caatgtgggt
      181 agttacagcg tattctggta ccagcagaag ccagggagtc ctccccggta ccttctgtac
      241 taccagtcag actcaaggaa acaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagccaatgc agggctgtta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccct atggcacagc agcgcttctt gcatcttcgg tggtgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01002439             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:24607:5087
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002439
VERSION     KCWK01002439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:24607:5087"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68177.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          155 c          126 g          108 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtaacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtatcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatgatg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caggtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcggcatggg atgatagcct gagaggttac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01002440             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:13874:5357
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002440
VERSION     KCWK01002440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13874:5357"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68178.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          148 c          131 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccgatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta agagtgtgca ctggtaccag cacaagccac cgcaggcccc tatcctggtc
      241 atctattatt ataccgaacg gccctcggcg atccctgagc gattctctgg ctccaaaaca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacactac tattgatcat ggctttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002441             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13886:13999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002441
VERSION     KCWK01002441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13886:13999"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..365
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <329..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68179.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       369..401
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>439
                     /gene="IGLC"
BASE COUNT           89 a          139 c          123 g           88 t
ORIGIN      
        1 acatggggac ggtgcctcag ccatggcctg gacccttctc ctcctcggcc tcctcgctta
       61 ctgcacagac tctgcgacct cctatgaact gactcagtca ccctcagtgt cagcggcctc
      121 gggacagccg gccaggatca cctgtggggg agacaacatt ggaactaaaa ctgtgcactg
      181 gtaccagcag aagccaccgc agggccctgt attggtcatc tttgctgata gtaaacggcc
      241 ctcagggatc cctgagcgat tctctggctc caactcaggg aacaccgcca ccctgaccat
      301 cagcagggtc gaggccgggg atgaggctga ctattactgt caggtgtggg acagtagtag
      361 taaatggata ttcggcgggg ggacccggct aaccgtccta ggtcagccca aggctgcccc
      421 ctcggtcact ctcttcccg
//
LOCUS       KCWK01002442             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:14204:7435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002442
VERSION     KCWK01002442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14204:7435"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68180.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          141 c          136 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctaa
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002443             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:20848:5135
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002443
VERSION     KCWK01002443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20848:5135"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68181.1"
                     /translation="DYYCQVFDDSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          160 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacga tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002444             376 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:9515:17315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002444
VERSION     KCWK01002444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 376)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9515:17315"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..338
                     /note="immunoglobulin light chain variable region"
     V_region        8..338
     V_segment       8..302
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <266..>310
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68182.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       303..338
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        339..>376
                     /gene="IGLC"
BASE COUNT           70 a          120 c           98 g           88 t
ORIGIN      
        1 acatgggcag tctgccctga ctcagcctcc ctcagtgtcc aagtctcttg gacagtcggt
       61 caccatctcc tgcactggaa ccagcagtga cattggtggt tatgatggcg tctcctggta
      121 ccagcagcac tcagggacag cccccagact cctgatttat gatgtcacta agcggccctc
      181 aggggtctcg gatcgcttct ctggctccaa gtctggcaac acggcctccc tcaccatctc
      241 tgggctccag actgaggacg aggctgatta ttattgttgc tcatatagga gtggaaacac
      301 ttggctattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      361 ggtcactctc ttcccg
//
LOCUS       KCWK01002445             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:8714:7417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002445
VERSION     KCWK01002445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8714:7417"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68183.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          153 c          121 g          112 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggaggtac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002446             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:13641:10667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002446
VERSION     KCWK01002446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13641:10667"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68184.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          148 c          130 g           96 t
ORIGIN      
        1 acagggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002447             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:21054:15712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002447
VERSION     KCWK01002447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:21054:15712"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..379
                     /note="immunoglobulin light chain variable region"
     V_region        58..379
     V_segment       58..343
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <307..>351
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68185.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       347..379
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        380..>417
                     /gene="IGLC"
BASE COUNT           85 a          130 c          116 g           86 t
ORIGIN      
        1 acatggggga cccttctcct cctcggcctc ctcgcttact gcacagtctc tgcgacctcc
       61 tatgaactga ctcagtcacc ctcagtgtca gcggcctcag gacagccggc caggatcacc
      121 tgtgggggag acaacattgg aattaaaact gtgcactggt accagcagaa gccaccgcag
      181 ggccctgtat tggtcatctt tgctgatagt aaacggccct cggggatccc tgagcgattc
      241 tctggctcca actcagggaa caccgccacc ctgaccatca gcagggtcga ggccggggat
      301 gaggctgact attactgtca ggtgtgggac agtagtagta aatggatatt cggcgggggg
      361 acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002448             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:18763:7937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002448
VERSION     KCWK01002448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18763:7937"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68186.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          160 c          120 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagtgttttt gatcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002449             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:14286:7799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002449
VERSION     KCWK01002449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14286:7799"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68187.1"
                     /translation="GYYCQVWDISSDHVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          141 c          138 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctttga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aacttgtgaa ctggtaccaa cagaggccac cgcaggcccc tgtgctggtc
      241 atctatgctg atagcgaacg gccctcaggg atccctgaac gaatctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tggctattac
      361 tgtcaggtgt gggacattag tagtgatcat gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002450             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:11266:8688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002450
VERSION     KCWK01002450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11266:8688"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68188.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           82 a          157 c          127 g          107 t
ORIGIN      
        1 acatggggtg gggtctcagg aggcagcgct ctcgggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcagtct gccctgactc
      121 agcctccctc agtgtccaag tctcttggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat tggtggttat gatggcgtct cctggtacca gcagcactca gggacagccc
      241 ccagactcct gatttatgat gtcactaagc ggccctcagg ggtctcggat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctca ccatctctgg gctccagact gaggacgagg
      361 ctgattatta ctgttgctca tataggagtg gaaacacttg gctattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002451             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:11497:9176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002451
VERSION     KCWK01002451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11497:9176"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..388
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68189.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       389..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           94 a          138 c          126 g          100 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagagctct ggggtgtctc caccatggcc tggactcctc
       61 tctggctcac cctcctcagt ctttgcacag gttctgtggt ttcttctgag ctgactcagg
      121 accctgcagt gtctgtggcc ttgggacaga cagtcaggat cacctgccaa ggagacagcc
      181 tcagaagtta ttatgcaagt tggtaccagc agaagccagg ccaggcccct atactgatcg
      241 tctatggtaa caattaccgg ccctcaggga tcccagagcg attctctggc tccagtacac
      301 gaaacacagc ttccttgacc atcactgggg ctcaggtgga agatgaggct gactattact
      361 gtgactcctg ggacagccgc ggaacccaat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002452             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:22804:14925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002452
VERSION     KCWK01002452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22804:14925"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..440
                     /note="immunoglobulin light chain variable region"
     V_region        92..440
     V_segment       92..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68190.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       407..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           94 a          153 c          118 g          113 t
ORIGIN      
        1 acatgggggt gtggggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc caagcctatg ctgactcagc cggcctccct
      121 ctcagcatct cctggagcat cagccagtct cacatgcacc ttcagcggtg gcatcactgt
      181 tgctggctac catatatatt ggtaccagca gaagccaggg agtccccccc ggtatcttct
      241 gaggtacaaa tcagactcag ataagggcca gggctctgga gtccccagcc gcttctctgg
      301 atccaaagat gcttcagcga acacagggat tttacgcata tctggactcc agtctgagga
      361 tgaggctgac tattactgtg ccattggaca cagcagcggt gattatatct tcggtgctgg
      421 gacccgtctc accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01002453             376 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:18894:12332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002453
VERSION     KCWK01002453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 376)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18894:12332"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..338
                     /note="immunoglobulin light chain variable region"
     V_region        14..338
     V_segment       14..299
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <263..>310
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68191.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       304..338
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        339..>376
                     /gene="IGLC"
BASE COUNT           93 a          109 c           98 g           76 t
ORIGIN      
        1 acatggggag gcctcctatg agctgacaca gccaccctca gtgtctgtgt ccccaggaca
       61 gacggccagg atcacctgct ctggagaaat actggcaaaa aaatatactc agtggttcca
      121 acagcagcca ggccaggccc ctttcctggt gatatataaa gacagtgaga ggccctcagg
      181 gatccctgag cgattctcta gctccagttc agggacaaca attaccttga ccatcagtgg
      241 ggcccaggca gaagatgagg ctgactatta ctgtcaatca gtagacagca gtggaaatct
      301 tccgttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      361 ggtcactctc ttcccg
//
LOCUS       KCWK01002454             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:25192:6606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002454
VERSION     KCWK01002454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:25192:6606"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..260
                     /note="immunoglobulin light chain variable region"
     V_region        4..260
     V_segment       4..220
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>232
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68192.1"
                     /translation="DYYCAIGHMSGNYVF"
     J_segment       228..260
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>298
                     /gene="IGLC"
BASE COUNT           65 a           88 c           77 g           68 t
ORIGIN      
        1 acatgggtac cacacacact ggtaccagca gaagccaggg agtcctcccc ggtatcttct
       61 gagatataaa tcagactcag ataagggcca gggctctgga gtccccagcc gcttctctgg
      121 atccaaagat gcttcagcga acacagggat tttacgcatc tctgggctcc agtctgagga
      181 tgaggctgac tattactgtg ccattgggca catgagcggt aattatgtct tcggttctgg
      241 gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01002455             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:11745:8746
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002455
VERSION     KCWK01002455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:11745:8746"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..330
                     /note="immunoglobulin light chain variable region"
     V_region        9..330
     V_segment       9..294
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <258..>302
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68193.1"
                     /translation="DYYCQVWDSSSEWVF"
     J_segment       295..330
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        331..>368
                     /gene="IGLC"
BASE COUNT           78 a          108 c          111 g           71 t
ORIGIN      
        1 acatgggctc ctatgagttg actcaggcac cctcagtgtc agcggcctca ggacagacgg
       61 ccaggatcac ctgtggggga gacaacattg gaagtaaaac tgtgcactgg taccaacaga
      121 aggcagcgca ggcccctgtg ctggtcatct ttgctgatag caaacggccc tcagggatcc
      181 ctgaccgatt ctctggctcc aactcaggga acaccgccac cctgaccatc agcggggtcg
      241 aggccgggga tgaggctgac tattactgtc aggtgtggga cagtagtagt gaatgggttt
      301 tcggcggagg gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      361 tcttcccg
//
LOCUS       KCWK01002456             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:19224:7320
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002456
VERSION     KCWK01002456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19224:7320"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..268
                     /note="immunoglobulin light chain variable region"
     V_region        8..268
     V_segment       8..225
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <197..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68194.1"
                     /translation="DYYCSSFAGRNNLFF"
     J_segment       239..268
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        269..>307
                     /gene="IGLC"
BASE COUNT           65 a           91 c           76 g           75 t
ORIGIN      
        1 acatggggga accagcagta atcttgggta ttttaatgct gtgtcttggt accaacaaca
       61 tccaggcaaa gcccccaaac tcatgattta cgacgtcact aagcggccct caggggtctc
      121 tgatcgcttc tctggctcca agtctggcaa cacggcctcc ctgaccatct ctgggctcca
      181 ggctgaggat gaggctgatt attactgcag ttcatttgcc ggcaggaaca atttattttt
      241 cggaggaggg acccggctga ccgtcctaag tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01002457             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:10158:17390
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002457
VERSION     KCWK01002457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10158:17390"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..403
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68195.1"
                     /translation="DYHCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          163 c          114 g          107 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagtcagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacacacac tggtaccaac agaagccagg gagtcccccc cggtatcttc
      241 tgaaatacaa atcagacaca gaccagggcc aggggtctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttctgcg aacacaggtc ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctatcactgt gccattggtc acagcagcgg tccatacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002458             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:13212:16154
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002458
VERSION     KCWK01002458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13212:16154"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68196.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          141 c          134 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatgg tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtattggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002459             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:25168:13528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002459
VERSION     KCWK01002459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:25168:13528"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68197.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           92 a          147 c          129 g           96 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct atactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002460             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:7296:19141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002460
VERSION     KCWK01002460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7296:19141"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68198.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          162 c          121 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtaataaaaa catgtactgg taccaacaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaactaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtttgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002461             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:9301:12055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002461
VERSION     KCWK01002461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9301:12055"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68199.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          151 c          119 g          110 t
ORIGIN      
        1 acatgggggg aggcagcact caggacagtc tccagcatgg cctggtctcc tctcctcctc
       61 acccttctca ttcacttcac agttccaggg tcctgggccc agtctgtgct gacgcagccg
      121 ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct cctgcactgg gagcagctcc
      181 aacattggag attattttgt gcagtggtac cagcaccttc caggaacggc ccccaaactc
      241 ctcatctatg aaaataataa gcggccctca gggatttctg atcgattctc tggctcccag
      301 tctggaacct cagcctccct gaccatcact ggactccagt ctgaggatga ggctgattat
      361 tactgccagt cctatgacag cagtttgatt gctgtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002462             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17303:6030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002462
VERSION     KCWK01002462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17303:6030"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68200.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          151 c          137 g           93 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaac taagtatgtg cactggtacc agcagaagcc accgcaggcc cctgtgttgg
      241 tcatctatgc tgataccaga cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cgggtatgag gctgactatt
      361 tctgtcaggt gtgggacgat agcagtgatc atccggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002463             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:20421:5151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002463
VERSION     KCWK01002463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20421:5151"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68201.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          157 c          115 g          115 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcaag ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtctt ataatgctgt gtcttggtac caacatcatc caggcaaagc
      241 cccccaactc ataatttttg aagtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgctgct catatgtagg cagcaacact tacatcttcg atgttgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002464             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:6097:13745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002464
VERSION     KCWK01002464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6097:13745"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..394
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68202.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           84 a          157 c          119 g          116 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcaa gctgccccga
      121 ctcagcctcc ctctgtgtcc gggtctcctg gacagtcggt caccttctcc tgcactggaa
      181 ccggcagtga ttttgggtct tataatgctg tgtcttggta ccaacagcat ccaggcaaag
      241 ccccccaact cataattttt gaggtcaata agcggccctc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag gctgaggatg
      361 aggctgatta ttactgctgc tcatatgtag gcagcaacac ttacatcttc gatgttggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002465             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:27510:9465
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002465
VERSION     KCWK01002465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:27510:9465"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..450
                     /note="immunoglobulin light chain variable region"
     V_region        117..450
     V_segment       117..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68203.1"
                     /translation="DYYCQSYDSNLNTHILF"
     J_segment       417..450
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           96 a          158 c          121 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag caactccaac attggagatt attatgtgca gtggtaccaa caccttccag
      241 gaacggcccc cagactcctc atctatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcaa cttgaatact catattttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01002466             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:7175:2824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002466
VERSION     KCWK01002466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7175:2824"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..445
                     /note="immunoglobulin light chain variable region"
     V_region        117..445
     V_segment       117..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68204.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          156 c          126 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggccctgtct
      121 gtactgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcgggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002467             414 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:11303:9139
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002467
VERSION     KCWK01002467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 414)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:11303:9139"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    31..376
                     /note="immunoglobulin light chain variable region"
     V_region        31..376
     V_segment       31..337
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <307..>348
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68205.1"
                     /translation="DYHCQVFDSSDVLF"
     J_segment       343..376
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        377..>414
                     /gene="IGLC"
BASE COUNT           84 a          134 c          103 g           93 t
ORIGIN      
        1 acatgggctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc accctccctg
       61 tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagcagtga cctcagtgtt
      121 ggtgataaaa acatgtactg gtaccaacag aagccaggga gcgctcccaa attattcctg
      181 tactacttct ccgactcaga caagcagctg ggacctgggg tccccaatcg agtctctggc
      241 tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctgggctcca gcctgaggac
      301 gaggccgatt atcactgtca ggtgtttgac agtagtgatg ttttattcgg aggagggacc
      361 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002468             397 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:25900:9066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002468
VERSION     KCWK01002468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 397)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:25900:9066"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..359
                     /note="immunoglobulin light chain variable region"
     V_region        11..359
     V_segment       11..319
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <287..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68206.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       322..359
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>397
                     /gene="IGLC"
BASE COUNT           83 a          131 c           96 g           87 t
ORIGIN      
        1 acatgggtcc aagcctatgc tgactcagcc ggcctccctc tctgcatctc ctggagcatc
       61 agccagtctc acatgcacct tcagcggtgg catcaatgtt gctgcctacc acatacactg
      121 gtaccagcag aagccaggga gtcctccccg gtatcttctg agatacaaat cagactcaga
      181 taaggaccag ggctctggag tccccagccg cttctctgga tccaaagatg cctcagcgaa
      241 cacagggatt ttacgcatct ctgggctcca gtctgaggat gaggctgact actactgtgc
      301 cattgggcac agcagcggtg attacatctt cgctgctggg acccgcctca ccgtcctagg
      361 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01002469             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:12806:12742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002469
VERSION     KCWK01002469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12806:12742"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..418
                     /note="immunoglobulin light chain variable region"
     V_region        88..418
     V_segment       88..381
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <337..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68207.1"
                     /translation="DYYCGAAFGSGLTWQYIF"
     J_segment       382..418
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>456
                     /gene="IGLC"
BASE COUNT           88 a          154 c          116 g           98 t
ORIGIN      
        1 acatggggca gcatctggga catgtcagcc atggcctgga cgcctctcct cctcagcctc
       61 ctcgctcact gcacaggctc tatggcctcc tatgagctga ctcagccacc ctcagtgtcg
      121 gtgtccccag gacagacagc cagcatcacc tgttctggaa ataatttggg gaatgtttat
      181 gcttactggt atcaacagaa gccaggccag gcccctctgc tggtcatcta caaagatacc
      241 aaccggccct cagggatccc tgagcgattt tctggctcca actcagggaa ctcggccacc
      301 ctgaccatca ccagggtcga ggccggggat gaggccgact attactgtgg tgcagccttt
      361 ggcagtggcc tcacctggca gtacatcttc gctcctggga cccggctcac cgtcctaggt
      421 cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002470             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:9650:22043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002470
VERSION     KCWK01002470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9650:22043"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..389
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68208.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       391..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          148 c          125 g          107 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctctcct
       61 tctcactctg ctggttcact gcacagggtc ctgggcccag tctgtgctga cgcagccgcc
      121 ctcagcatct ggggcccccg ggcagagggt caccatctcc tgctctggga gcagctccaa
      181 catcggggcg ggtttttatg tttcctggta ccagcagttc ccaggaacag cccccaaact
      241 cctcatcttt gaaaataata agcgaccctc aggggtttct gaccgattct ctggctccaa
      301 gtctggttcc tcagcctccc tgaccatcac tggactccaa tctgaggatg aggctgatta
      361 ttattgttca tcatgggaaa gcagcctgaa ttgggtattc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002471             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:13515:6015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002471
VERSION     KCWK01002471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13515:6015"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68209.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       408..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          157 c          118 g          110 t
ORIGIN      
        1 acatggggca gccccagctc tggagccagg gatcccttcc aatatcagca ccatggcctg
       61 gactctgctc ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt
      121 agtgactcag gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcacctgtgc
      181 ttccagcact ggagcagtca ccagtggtca ctctccacac tggttccagc agaaacctgg
      241 acaagccccc aagacactga tttataatac aaactacaga cactcctgga ctcctgcccg
      301 gttctcaggc tccctccttg ggggtaaagc tgccctgaca ctgtcaggtg cgcagcctga
      361 ggatgaggct gagtattatt gtttactgta ctatagtggt gctcagctgt tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01002472             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:18411:4825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002472
VERSION     KCWK01002472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18411:4825"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68210.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          158 c          126 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtggtg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcactctg agtagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgtt ctaccagtcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgcaaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002473             517 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:13937:18630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002473
VERSION     KCWK01002473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 517)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13937:18630"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    149..479
                     /note="immunoglobulin light chain variable region"
     V_region        149..479
     V_segment       149..442
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <404..>451
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68211.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       443..479
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        480..>517
                     /gene="IGLC"
BASE COUNT          106 a          159 c          137 g          115 t
ORIGIN      
        1 acatggggag agtatgaaga gagggagaga tttgggtgaa gcgcagcctc agctgtgggt
       61 acagaaggca ggactcagga caatctccag catggcctgg ttccctctcc tcctcaccct
      121 cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagcctc cctcagcgtc
      181 tgaggccgcc gggaagagtg tcaccatctc ctgttctgga agcagctcca acatcggaag
      241 taatagtgta tcctggtacc aacaactccc agaaacggct cccaaactcc tcatgtatta
      301 taatcatcgg cgagcctcag gtgtctctga ccgattctct ggctccaagt ctggcacttc
      361 agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt actgcgcagt
      421 atgggatgat agcctgaccg gttacatctt cggtgctggg acccggctca ccgtcctagg
      481 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01002474             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:8006:7244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002474
VERSION     KCWK01002474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8006:7244"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68212.1"
                     /translation="DYYCSSYAGSNILVF"
     J_segment       405..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          154 c          123 g          108 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcggcact ctcgggacat ctccaccatg gcctgggatc
       61 tgctcctctt caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctccctc aatgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat tggtagttat aaccgtgtct cctggtacca acatcaccca gacaaagccc
      241 ccaaagtcat gatttatgag ggcagtcagc ggccctcagg ggtctctgat cgcttctctg
      301 cctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ttgcagctca tatgcaggca gcaatatttt ggttttcggc ggagggaccc
      421 ggctaaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002475             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:10056:12262
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002475
VERSION     KCWK01002475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10056:12262"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..386
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68213.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          152 c          116 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccaga ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta ataatgtgtc ctggtaccag cacctcccag gaacagctcc caaactcctc
      241 atctattata atgatcaacg aggctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcgt gggatgatag cctgagtagt tacatcttcg ctgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002476             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:8301:17064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002476
VERSION     KCWK01002476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8301:17064"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..251
                     /note="immunoglobulin light chain variable region"
     V_region        1..251
     V_segment       1..214
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68214.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       215..251
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           61 a           92 c           70 g           66 t
ORIGIN      
        1 caacatcgga agtaataatg tgtcctggta ccagcacctc ccaggaacag ctcccaaact
       61 cctcatctat tataatgatc aacgaggctc aggtgtctct gaccgattct ctggctccaa
      121 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      181 ttactgcgca gcgtgggatg atagcctgag cagttacatc ttcgctgctg ggacccggct
      241 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002477             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:24443:10319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002477
VERSION     KCWK01002477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:24443:10319"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68215.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          151 c          116 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctccggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002478             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:14023:15115
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002478
VERSION     KCWK01002478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14023:15115"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68216.1"
                     /translation="DYYCQVWDSDSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           96 a          143 c          132 g           91 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggtactgcga cctcctatga actgactcag
      121 ccaccctcag tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta aaaatgtgca ctggtaccag cagaagccag cgcagggccc tgtattggtc
      241 atgtttgctg ataccagacg gccctcaggg atccctgacc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtga tagtaaatgg atattcggcg gagggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002479             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:9100:17909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002479
VERSION     KCWK01002479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9100:17909"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68217.1"
                     /translation="DYYCAMWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          162 c          111 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgaacagt ggcatcaatg
      181 ttggtagtta cagcattttc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002480             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:16003:21898
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002480
VERSION     KCWK01002480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16003:21898"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68218.1"
                     /translation="DYYCQMYDNSDVLF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          160 c          121 g          108 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtact gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gaagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcaactgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag atgtatgaca atagtgatgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002481             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:13670:1975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002481
VERSION     KCWK01002481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13670:1975"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68219.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          157 c          122 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctagcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002482             276 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:3743:8113
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002482
VERSION     KCWK01002482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 276)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 276)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..276
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:3743:8113"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..238
                     /note="immunoglobulin light chain variable region"
     V_region        8..238
     V_segment       8..201
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <166..>210
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68220.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       204..238
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        239..>276
                     /gene="IGLC"
BASE COUNT           57 a           82 c           75 g           62 t
ORIGIN      
        1 acatgggaga agccagggag cgctcccagg ttattcctgt actactactc cgactcagac
       61 aagcagctgg gacctggggt ccccaatcga gtctctggct ccaaggagac ctcaagtaac
      121 acagcgtttt tgctcatctc tgggctccag cctgaggacg aggccgatta ttactgtcag
      181 gtgtatgaca gtagtgctaa tgtcttattc ggaggaggga cccggctgac cgtcctaggt
      241 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002483             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:9453:12452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002483
VERSION     KCWK01002483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:9453:12452"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..400
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68221.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       403..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          159 c          121 g          107 t
ORIGIN      
        1 atggggggca gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccca gcctgtgctg acccagccaa cctccctctc
      121 agcatctccg ggagcatcag ccagactcag ctgcaccttg agcagtggcg tcaatgtggg
      181 tagttacagc atattctggt accagcagaa gccagggagt cctccccggt accttctgta
      241 ctaccagtca gactcaagga agcaccaggg ctctggagtc cccagccgct tctctggatc
      301 caaagatgct tcagccaatg cagggctgtt actgatctct gggctccagt ctgaagatga
      361 ggctgactat tactgtgccc tatggcacag cagcgcttct tgcatcttcg gtggtgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002484             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:16695:16236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002484
VERSION     KCWK01002484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16695:16236"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68222.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          142 c          133 g           93 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgaac tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaattaaa actgtacact ggtaccagca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgat agtaagcggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc gccctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002485             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:11296:11224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002485
VERSION     KCWK01002485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11296:11224"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68223.1"
                     /translation="DYYCQVWDISTDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          144 c          133 g          100 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagc ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccagggtc acctgtggag gagacaacct
      181 tggatatgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctaaccga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacattagta ctgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002486             331 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:23883:10474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002486
VERSION     KCWK01002486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 331)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23883:10474"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..293
                     /note="immunoglobulin light chain variable region"
     V_region        5..293
     V_segment       5..256
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <221..>265
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68224.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       258..293
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        294..>331
                     /gene="IGLC"
BASE COUNT           69 a          102 c           84 g           76 t
ORIGIN      
        1 actgggaggg acagtcactc tcacctgtgc ttccagcact ggagcagtca ccagtggtca
       61 ctctccacac tggttccagc agaaacctgg acaagccccc aagacactga tttataatac
      121 aaactacaga cactcctgga ctcctgcccg gttctcaggc tccctccttg ggggtaaagc
      181 tgccctgaca ctgtcaggtg cgcagcctga ggatgaggct gagtattatt gtttactgta
      241 ctatagtggt gctcagctgt tattcggagg agggacccgg ctgaccgtcc taggtcagcc
      301 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002487             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11416:2184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002487
VERSION     KCWK01002487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11416:2184"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..423
                     /note="immunoglobulin light chain variable region"
     V_region        93..423
     V_segment       93..384
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68225.1"
                     /translation="DYYCSAWDSSLTGGFF"
     J_segment       386..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          150 c          116 g          102 t
ORIGIN      
        1 acatggggaa gacaggactc aggacaatct ccagcatggc ctgcttccct ctcatcctca
       61 ccgtcctcac tcactgtgca ggatcctggg cccagtctgt gctgactcaa ccaccctcag
      121 cgtctggggc ccccgggcag agtgtcacca tctcctgttc tggaagcagc tccaacatcg
      181 gaagtaatta tgtatactgg taccagcagt tctcagggaa ggcccccaaa ctcctcatcc
      241 ataataataa tcagcgaccc tcaggggtcc ctgatcgatt ctctggctcc aagtctggca
      301 cgtcagcctc cctggacatc agtgggctcc agtccgagga tgaggctgat tattactgct
      361 cagcatggga tagcagtctg accggtggct ttttcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002488             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:17594:17075
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002488
VERSION     KCWK01002488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17594:17075"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..314
                     /note="immunoglobulin light chain variable region"
     V_region        7..314
     V_segment       7..277
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68226.1"
                     /translation="DYYCHVYDSSSNVLF"
     J_segment       280..314
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           74 a          107 c           94 g           77 t
ORIGIN      
        1 acatggggga gcgtcggcca gactcccctg caccctgagc agtgacctca gtgttggtgg
       61 taaaaacctg tactggtacc agcagaagcc agggcgcgct cccaggtttt tcctgtacta
      121 caactccgac tcagacaagc agctgggacc tggggtcccc aatcgagtct ctggctccaa
      181 ggagacctca agtaacacag cgtttttgct catctccggg ctccagcctg aggacgaggc
      241 cgattattac tgtcacgtat atgacagtag tagtaatgtc ttattcggag gagggacccg
      301 tctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002489             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:8179:17948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002489
VERSION     KCWK01002489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8179:17948"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..389
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68227.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       391..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          148 c          126 g          104 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctctcct
       61 tctcactctg ctggttcact gcacagggtc ctgggcccag tctgtgctga cgcagccgcc
      121 ctcagcatct ggggcccccg ggcagagggt caccatctcc tgcactggga gcagctccaa
      181 catcggggcg ggtttttatg tatcctggta ccagcagttc ccaggaaaag cccccaagct
      241 cctcatcttt gaaaataaca agcgaccctc aggggtttct gaccgattct ctggctccaa
      301 gtctggttcc tcagcctccc tgaccatcac tggactccaa tctgaggatg aggctgatta
      361 ttattgttca tcatgggaaa gcagcctgaa ttgggtattc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002490             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:20590:4738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002490
VERSION     KCWK01002490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20590:4738"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68228.1"
                     /translation="DYYCQMWGMTSDHPVF"
     J_segment       391..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          142 c          140 g           93 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccaatgatc tgactcagcc
      121 accctcggtg tcagagtccc caggacagac ggccaggatc acctgtgggg gagacaagat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctc tgttggtcat
      241 ctctggtgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcagatgtgg ggcatgacta gtgatcatcc ggtattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002491             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:18565:15229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002491
VERSION     KCWK01002491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18565:15229"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..395
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68229.1"
                     /translation="DYYCCSYRSGPTWVF"
     J_segment       396..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           79 a          156 c          126 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg atcctgggct cagtctgccc tgactcagcc
      121 tccctcagtg tccaagtctc ttggacagtc ggtcaccatc tcctgcactg gaaccagcag
      181 tgacattgga ggttataatg gcgtctcctg gttccagcag cactcaggga cagcccccaa
      241 actcctgatt tatgatgtga ataagcggcc ctcaggggtc tctgatcgct tctctggctc
      301 caagtctggc aacacggcct ccctgaccat ctctgggctc caggctgagg acgaggctga
      361 ttattactgc tgctcatata ggagtggacc cacttgggtt ttcggcggag ggacccgcct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002492             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:11289:3626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002492
VERSION     KCWK01002492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11289:3626"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68230.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           90 a          154 c          120 g          109 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002493             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20065:14534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002493
VERSION     KCWK01002493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20065:14534"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68231.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          143 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctgact ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002494             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:16446:20186
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002494
VERSION     KCWK01002494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16446:20186"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68232.1"
                     /translation="DYYCHVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          149 c          128 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtaca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcacgtgt gggacacaac tattgatcac ggcttgttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002495             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18652:10474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002495
VERSION     KCWK01002495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18652:10474"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68233.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          157 c          126 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagca agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca agtcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgaggggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002496             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:6875:5682
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002496
VERSION     KCWK01002496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6875:5682"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68234.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          149 c          135 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta aatatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
      241 atctatgctg ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggt gtcgaggccg ggtatgaggc tgactatttc
      361 tgtcaggtgt gggacgatag tagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002497             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:26721:10073
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002497
VERSION     KCWK01002497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:26721:10073"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68235.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          162 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc cagggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcgtag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002498             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:20804:11967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002498
VERSION     KCWK01002498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20804:11967"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..395
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <351..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68236.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       396..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           92 a          149 c          133 g           96 t
ORIGIN      
        1 acatgggggc tggcttcaga agcagcatct gggacatgtc agccatggcc tggacgcctc
       61 tcctcctcag cctcctcgct cactgcacag gctctgtggc ctcctatgag ctgactcagc
      121 caccctcagt gtcggtgtcc ccaggacaga cagccagcat cacctgctct ggaaataaat
      181 tggggaatgt atatgcttac tggttccagc agaagccagg ccaggcccct gtagtggtca
      241 tctacaaaga taccaaccgg ccctcaggga tccctgagcg attctctggc tccgactcag
      301 ggaacacggc caccctgacc atcagcaggg tcgaggctgg ggatgaggcc gactattttt
      361 gtgctgcagc ctatggcagt ggcagcagct ggcagtgggt attcggcgga gggacccggc
      421 taatcgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002499             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:13163:17851
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002499
VERSION     KCWK01002499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:13163:17851"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68237.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          162 c          123 g          105 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcgtg atttatgagg tcaatcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct gccaacacgg cctccctgac catctctggc ctccagcctg aggacgaggc
      361 tgattattac tgcagctcat atgcaggcag cgacactttc gtgttgttcg gaggagggac
      421 ccgactgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002500             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:8184:8802
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002500
VERSION     KCWK01002500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8184:8802"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..249
                     /note="immunoglobulin light chain variable region"
     V_region        6..249
     V_segment       6..214
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <177..>221
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68238.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       216..249
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        250..>287
                     /gene="IGLC"
BASE COUNT           58 a           84 c           74 g           71 t
ORIGIN      
        1 atggggggta ttataacgct gtgtcttggt accaacagca tccaggcaaa gcccccaaac
       61 tcataatttt tgacgtcatt aagcggccct caggggtctc tgatcgcttc tctggctcca
      121 agtctggcga cacggcctcc ctgaccatct ctgggctccg ggctgaggat gaggctgatt
      181 attactgcag ctcatatgca ggcagaaata attttttatt cggaggaggg acccggctga
      241 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002501             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:11486:18302
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002501
VERSION     KCWK01002501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:11486:18302"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68239.1"
                     /translation="DYYCSAWDSSLTGGLF"
     J_segment       406..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          157 c          124 g          105 t
ORIGIN      
        1 acatggggag cttcagctgt ggctagagaa gacaggactc aggacaatct ccagcatggc
       61 ctgcttccct ctcatcctca ccgtcctcac tcactgtgca ggatcctggg cccagtctgt
      121 gctgactcaa ccaccctcag cgtctggggc ccccgggcag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gatgtaattt tgtatactgg taccagcagt tctcagggaa
      241 ggcccccaaa ctcctcatcc ataatagtaa tcagcgaccc tcaggggtcc ctgatcgatt
      301 ccctggctcc aagactggca cgtcagcctc cctggccatc agtgggctcc agtccgagga
      361 tgaggctgac tattactgct cagcatggga tagcagtctg accggtggct tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01002502             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:15038:14487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002502
VERSION     KCWK01002502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15038:14487"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68240.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          162 c          109 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt tagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002503             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:7193:13860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002503
VERSION     KCWK01002503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7193:13860"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68241.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          142 c          134 g           95 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gaattgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc aacagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgatagtaga cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctgtt cccg
//
LOCUS       KCWK01002504             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:4972:15165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002504
VERSION     KCWK01002504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:4972:15165"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68242.1"
                     /translation="DYYCQTWDTGIQVF"
     J_segment       399..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           88 a          166 c          119 g           98 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggg
      181 cacagcagct acaccatcgc atggcatcag cagcagcaag ggatggcccc tcggtacttg
      241 atgtggctta aaactgatgg cagccacacc aaggggaacg ggatccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatact ggcattcagg tattcggcgg agggacccga
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002505             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:21728:12375
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002505
VERSION     KCWK01002505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21728:12375"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..229
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68243.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       233..269
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           64 a           86 c           92 g           65 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaagtga agttgtcaac tggtaccaac agaagccacc
       61 gcaggcccct gtggtggtca tctatgctga ttatgaacgg ccctcaggga tccctgagcg
      121 attctctggc tccaaatcag ggaacacggc caccctgacc atcagcggag tcgcggccgg
      181 ggatgaggct gactattact gtcaggtttg ggacatttat actgatcatc cggtgttgtt
      241 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01002506             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:13058:15909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002506
VERSION     KCWK01002506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13058:15909"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..268
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <230..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68244.1"
                     /translation="DYYCAVWDNSLTSPLF"
     J_segment       275..305
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           71 a          108 c           85 g           79 t
ORIGIN      
        1 acatgggggg actcccgggc agagtgtcac catctcttgc tctggaagca actccaacat
       61 tggaaataat tatgtatact ggtaccagca cctcccagga acggccccca agctcctcat
      121 ctattatagt tatcagcgac cctcaggggt ccctgaccga ttctctggct ctaagtctgg
      181 cacctcagcc tccctggcca tcactggtct ccgaactgag gatgaggctg attattactg
      241 tgcagtatgg gataacagcc tgaccagtcc gttgttcgga ggagggaccc ggctgaccgt
      301 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002507             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:9028:18704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002507
VERSION     KCWK01002507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:9028:18704"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..408
                     /note="immunoglobulin light chain variable region"
     V_region        78..408
     V_segment       78..372
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68245.1"
                     /translation="LYYCCSYTTSSTYIF"
     J_segment       373..408
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           82 a          153 c          103 g          108 t
ORIGIN      
        1 acatggggga cgtctccacc atggcctgga ctctgctcct cgtcaccctc ctcactcaag
       61 gcacaggatc ctgggctcag tctgccccga ctcagcctcc ctctgtgtct gggtctcctg
      121 gacagtcggt caccatctcc tgcactggaa ccagcactga cgttggtggt tataactctg
      181 tctcctggta ccaacaggac ccaggcaaag cccccaaact catcatttat ggtgtcagta
      241 atcggccctc aggggtctct gatcgcttct ctggctccaa gtctggcaac acggcctccc
      301 tgaccatctc tgggctccag gctgaggacg aggctcttta ttactgttgt tcatatacaa
      361 ccagtagcac ttacatcttc ggtactggga cccggctaac cgtcctaggt cagcccaagg
      421 cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002508             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:14489:13843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002508
VERSION     KCWK01002508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14489:13843"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68246.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       400..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           90 a          154 c          123 g          107 t
ORIGIN      
        1 acatgggggt ggggtctcag gaggcggcac tctcgggaca tctccaccat ggcctgggat
       61 ctgctcctct tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagcctccct caatgtctgg gtctcctgga cagtcggtca ccatctccta cactggaacc
      181 agcagtgaca ttggtggtta taaccgtgtc tcctggtacc aacagcaccc aggcaaagac
      241 cccaaattca tgatttatga ggtcagtcaa cggccctcag gggtctctga tcgtatctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccagac tgaggatgag
      361 gctggttatt actgcagctc atttgcaggt accaacactg gcttaatcgg tggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002509             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:14672:7494
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002509
VERSION     KCWK01002509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14672:7494"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68247.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           96 a          161 c          110 g          107 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcaactcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 gcctaccaca tacactggta ccagcagaag ccagggagtc ccccccggta tcttctgagt
      241 tacaaatcag actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaaaatgctt caacaaacac aggcatttta cacatctctg ggctccagtc tgaggatgag
      361 gctgactatt tctgtgccat tggacacagc agcggtcctt acatcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01002510             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:9453:8452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002510
VERSION     KCWK01002510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9453:8452"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68248.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           97 a          138 c          124 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagacacatt
      181 gccaaaaaaa tatgcttatt ggttccagcg gaaggcaggc cagtcccctg tgctgatcat
      241 ctatgaggac aacaaacggt cttctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaaactg actactactg
      361 ttactcagca gacagtagtg gtaatggctt attcggagga gggacccgac tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002511             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:14799:16604
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002511
VERSION     KCWK01002511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14799:16604"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68249.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          143 c          132 g          101 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtgaagt tgtcaactgg taccaacaga agccaccgca ggcccctgtg gtggtcatct
      241 atgctgatta tgaacggccc tcagggatcc ctgaccgatt ctctggctcc aaatcaggga
      301 acacggccac cctgaccatc agcggagtcg cggccgggga tgaggctgac tattactgtc
      361 aggtttggga catttatact gatcatccgg tgttgttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002512             326 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:18786:11713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002512
VERSION     KCWK01002512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 326)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18786:11713"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..288
                     /note="immunoglobulin light chain variable region"
     V_region        9..288
     V_segment       9..252
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>260
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68250.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       256..288
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        289..>326
                     /gene="IGLC"
BASE COUNT           72 a           93 c           99 g           62 t
ORIGIN      
        1 acatgggggg acagccggcc aggatcacct gtgggggaga caacattgga actaaaactg
       61 tgcactggta ccagcagaag ccaccgcagg gccctgtatt ggtcatcttt gctgatagta
      121 aacggccctc agggatccct gagcgattct ctggctccaa ctcagggaac accgccaccc
      181 tgaccatcag cagggtcgag gccggggatg aggctgacta ttactgtcag gtgtgggaca
      241 gtagtagtaa atggatattc ggcgggggga cccggctaac cgtcctaggt cagcccaagg
      301 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002513             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:14454:13700
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002513
VERSION     KCWK01002513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14454:13700"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68251.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          155 c          117 g          112 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catacactgg tatcagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggcctgg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaat acagggattt tacacatctc tggtttccag tctgaggatg
      361 aggctgacta ttactgtgcc attggccacg gcagcggtga ttacatcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002514             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:12969:20875
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002514
VERSION     KCWK01002514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12969:20875"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68252.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          153 c          111 g          118 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttgctaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcatc agggctctgg agtccccagt cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002515             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:17532:11743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002515
VERSION     KCWK01002515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17532:11743"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..408
                     /note="immunoglobulin light chain variable region"
     V_region        63..408
     V_segment       63..371
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68253.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       372..408
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           85 a          152 c          107 g          102 t
ORIGIN      
        1 acatgggggc cctgactcct ctcctcctcc tgctcctctc tcactgcaca ggttccctct
       61 cccagcctgt gctgactcag ccaccctccc tgtctgcatc cccgggagca tcggccagac
      121 tcccctgcac cctgagcagt gacctcagtg ttggtaataa aaacatgtac tggtaccaac
      181 agaagccagg gagcgctccc aggttattcc tgtactacta ctccgactca gacaagcagc
      241 tgggacctgg ggtccccaat cgagtctctg gctccaagga gacctcaact aacacagcgt
      301 ttttgctcat ctctgggctc cagcctgagg acgaggccga ttattactgt caggtgtttg
      361 acagtagtgc tgtgttattc ggaggaggga cccgactgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002516             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:8404:3807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002516
VERSION     KCWK01002516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8404:3807"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68254.1"
                     /translation="DYHCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           96 a          162 c          113 g          105 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gtcagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgactacca cacacactgg taccaacaga agccagggag tcccccccga tatcttctga
      241 aatacaaatc agacacagac cagggccagg ggtctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acaggtcttt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta tcactgtgcc attggtcaca gcagcggtcc atacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002517             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:8608:21405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002517
VERSION     KCWK01002517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:8608:21405"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..392
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68255.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           87 a          156 c          116 g          115 t
ORIGIN      
        1 acatggggct gggatctcag gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaagc tgccccgact
      121 cagcctccct ctgtgtccgg gtctcctggg cagtcggtca ccatctcctg cactggaacc
      181 agcagtgata ttgggtctta taatgctgtg tcttggtacc aacaacatcc aggcaaagcc
      241 ccccaactca taatttttga ggtcaataag cggccctcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatttctg ggctccaggc tgaggatgag
      361 gctgattatt actgctgctc atatgtaggc agcaacactt acatcttcga tgttgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01002518             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:12528:11908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002518
VERSION     KCWK01002518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12528:11908"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68256.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          139 c          138 g           98 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagg
      121 caccctcgat ttcagtgtcc cccggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtgaac tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tgtatgctga tagcgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacatgaat agtcatcatc tattattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002519             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:13198:17610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002519
VERSION     KCWK01002519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13198:17610"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68257.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcga ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002520             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:10929:11962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002520
VERSION     KCWK01002520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10929:11962"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..424
                     /note="immunoglobulin light chain variable region"
     V_region        106..424
     V_segment       106..392
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68258.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       393..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           95 a          139 c          127 g          101 t
ORIGIN      
        1 acatggggag ctgtgggctc agaagcagag ctctggggtg tctccaccat ggcctggact
       61 cctctctggc tcaccctcct cagtctttgc acaggttctg tggtttcttc tgagctgact
      121 caggaccctg cagtgtctgt ggccttggga cagacagtca ggatcacctg ccaaggagac
      181 agcctcagaa gttattatgc aagttggtac cagcagaagc caggccaggc ccctatactg
      241 atcgtctatg gtaacaatta ccggccctca gggatcccag agcgattctc tggctccagt
      301 acacgaaaca cagcttcctt gaccatcact ggggctcagg tggaagatga ggctgactat
      361 tactgtgact cctgggacag ccgcggaacc caattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002521             295 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:9492:4593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002521
VERSION     KCWK01002521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 295)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9492:4593"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..257
                     /note="immunoglobulin light chain variable region"
     V_region        5..257
     V_segment       5..221
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <185..>229
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68259.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       222..257
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>295
                     /gene="IGLC"
BASE COUNT           71 a           83 c           83 g           58 t
ORIGIN      
        1 acatggggac aacattggaa ttaaaaatgt ccactggtac cagcagaagc cagcacaggc
       61 ccctgtggta gtcatctatg ctgataacaa acggccctca gggatccctg agcgactctc
      121 tggctccaac tcagggaata ttgccaccct gaccatcagc agggtcgagg ccggggatga
      181 ggcagactat tactgtcagg tgtgggacag tagtagtaaa tgggtattcg gcggagggac
      241 ccggctaacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002522             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:12772:14732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002522
VERSION     KCWK01002522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12772:14732"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68260.1"
                     /translation="DYYCAIGHSSGNYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          155 c          119 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgtt gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctcg catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catacactgg taccagcgga agccagggag tcctccccgg tatcttctga
      241 gatacaagtc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acaggaattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtaa ttacatcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002523             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:11390:10206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002523
VERSION     KCWK01002523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11390:10206"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    69..399
                     /note="immunoglobulin light chain variable region"
     V_region        69..399
     V_segment       69..362
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <324..>371
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68261.1"
                     /translation="DYYCAVWDNSLTSPLF"
     J_segment       369..399
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        400..>437
                     /gene="IGLC"
BASE COUNT           82 a          146 c          107 g          102 t
ORIGIN      
        1 acatggggag catggcctgg ttccctctcg tcctcaccct cctcactcac tgtgcagggt
       61 cctgggccca gtctgtgctg actcagccac cctcagcgtc tgggactccc gggcagagtg
      121 tcaccatctc ttgctctgga agcaactcca acattggaaa taattatgta tactggtacc
      181 agcacctccc aggaacggcc cccaagctcc tcatctatta tagttatcag cgaccctcag
      241 gggtccctga ccgattctct ggctctaagt ctggcacctc agcctccctg gccatcactg
      301 gtctccgaac tgaggatgag gctgattatt actgtgcagt atgggataac agcctgacca
      361 gtccgttgtt cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct
      421 cggtcactct cttcccg
//
LOCUS       KCWK01002524             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:7578:11432
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002524
VERSION     KCWK01002524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:7578:11432"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68262.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          162 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca aacagctggg acctggggta cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002525             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:6739:19345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002525
VERSION     KCWK01002525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:6739:19345"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68263.1"
                     /translation="DYYCQVWDISSDHVLF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          139 c          141 g           98 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctccgcggc ctcctttgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga acttgtgaac tggtaccaac agaggccacc gcaggcccct gtgctggtca
      241 tgtatgctga tgacgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggagtacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacattagt agtgatcatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002526             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:27786:12093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002526
VERSION     KCWK01002526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:27786:12093"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68264.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          161 c          120 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acatggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002527             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:19042:17300
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002527
VERSION     KCWK01002527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19042:17300"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68265.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       398..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           86 a          155 c          123 g          105 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcatctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagtattgac aacggctttg tgtactggta ccagcagcgg ccgggcagcg ctcccaccac
      241 tgtgatttac aaagataacc aaagaccctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctgga ctgaaatctg aggacgaggc
      361 tgactattac tgtcagtctt atgacagcag cagtgtatta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002528             277 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:20664:23192
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002528
VERSION     KCWK01002528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 277)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:20664:23192"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..239
                     /note="immunoglobulin light chain variable region"
     V_region        8..239
     V_segment       8..202
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <164..>211
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68266.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       203..239
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        240..>277
                     /gene="IGLC"
BASE COUNT           53 a           93 c           70 g           61 t
ORIGIN      
        1 acatggggtc tcctggtacc aacaacatcc aggcacagcc cccaaactcg tgatttatga
       61 ggtcaatcag cggccctcag gggtctctga tcgcttctct ggctccaagt ctgacaacac
      121 ggcctccctg accatctctg gcctccagcc tgaggacgag gctgattatt actgcagctc
      181 gtatgcaggc agcgacactt tcgtgttatt cggaggaggg acccggctga ccgtcctagg
      241 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002529             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:24779:13156
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002529
VERSION     KCWK01002529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:24779:13156"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68267.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           92 a          161 c          108 g          113 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttta gcagtggcat caatgttggt
      181 agttacagca tattctggta ccagcagaag ccagggagtc ctccccggta ccttctctac
      241 tactactcag actcaagtaa acaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cggccaatgc aggcctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccat atggcacagc agcgcttctt acttcttcgg tactgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01002530             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:20664:7143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002530
VERSION     KCWK01002530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20664:7143"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68268.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           89 a          157 c          121 g          112 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacgtacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc aggggtctgg ggtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tctttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002531             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10418:17339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002531
VERSION     KCWK01002531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10418:17339"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..395
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68269.1"
                     /translation="DYYCQSFDSSTVLF"
     J_segment       401..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           81 a          157 c          128 g          107 t
ORIGIN      
        1 acatgggggg ctgtggctca ggaagcagag cctggagcat ctccaccatg gcctgggctc
       61 cgctcctcct caccctcctc gctcactgca cagggtcttg ggctgaggtt gtgttcactc
      121 agccccaatc tgtgtcgggg tctccggggc agacggtcac catctcctgc acccgcagca
      181 gtggcagcat tggcaacagc tatgtgtact ggttccagca gcggccgggc agcgtcccca
      241 ctattgtgat ttacaaagat gaccaaagac cctctggggt ccctgatcgg ttctctggct
      301 ccatcgacag ctcctccaac tctgcctccc tcaccatctc tggactgaag tctggggacg
      361 aggctgacta ttactgtcag tcttttgaca gcagcactgt cttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002532             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:20501:21038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002532
VERSION     KCWK01002532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20501:21038"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68270.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          158 c          119 g          109 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcacc tccaacatcg gaagcaataa tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctctttt attataatga tcaacgcgcc tcaggtgtct ctgaccgatt
      301 ctcttgctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgataacctg agcggctaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01002533             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:19130:10826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002533
VERSION     KCWK01002533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19130:10826"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..419
                     /note="immunoglobulin light chain variable region"
     V_region        103..419
     V_segment       103..389
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68271.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       390..419
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>459
                     /gene="IGLC"
BASE COUNT           89 a          141 c          129 g          100 t
ORIGIN      
        1 acatgggggg tgggctcaga agcagagctc tggggtgtct ccaccatggc ctggactcct
       61 ctctggctca ccctcctcag tctttgcaca ggttctatgg tttcttctga gctgactcag
      121 gaccctgcag tgtctgtggc cttgggacag acagtcagga ttacctgcca aggagacagc
      181 ctcagaagct cttatgcaag ctggtaccaa cagaggccag gccaggcccc tgtgctggtc
      241 gtctatggta acaactaccg gccctcaggg atcccagagc gattctctgg ctcctactca
      301 cgaaacacag cttccttgac catctctggg gctcaggtgg aagatgaggc tgactattac
      361 tgtgactcct gggacagcag cggaacccaa ttcggaggag ggacccggct gaccgtcctg
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002534             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:22378:7539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002534
VERSION     KCWK01002534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:22378:7539"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..250
                     /note="immunoglobulin light chain variable region"
     V_region        7..250
     V_segment       7..211
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <178..>222
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68272.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       213..250
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        251..>288
                     /gene="IGLC"
BASE COUNT           58 a           85 c           72 g           73 t
ORIGIN      
        1 acatgggggg cgggttttta tgtttcctgg taccagcagt tcccaggaac agcccccaaa
       61 ctcctcatct ttgaaaataa taagcgaccc tcaggggttt ctgaccgatt ctctggctcc
      121 aagtctggtt cctcagcctc cctgaccatc actggactcc aatctgagga tgaggctgat
      181 tattattgtt catcatggga aagcagcctg aattgggtat tcggcggagg gacccggctg
      241 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002535             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:7785:8513
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002535
VERSION     KCWK01002535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:7785:8513"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68273.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          159 c          118 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttggtgtcta ccacatacac tggtaccaac tgaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttgcgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002536             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:21814:4558
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002536
VERSION     KCWK01002536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21814:4558"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68274.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          156 c          125 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaagtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002537             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18457:13719
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002537
VERSION     KCWK01002537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18457:13719"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..401
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68275.1"
                     /translation="DYYCSSYEGTNSFIF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          158 c          121 g          107 t
ORIGIN      
        1 acatggggtg gggtctcagg aggcagcgct ctcaggacgt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggaccctg ggctcaggct gccctgactc
      121 agcctccctc tgtgtctggg tctcccggac agtcggtcac catctcctgc acgggaacca
      181 gcagtgacat cggtggttat aactatgtct cctggtacca gcagcaccca ggcaaagccc
      241 ccaaactcat gatttatgat gtcagtaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaaatc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgcagctca tatgaaggca ccaacagttt catcttcggt gttgggaccc
      421 ggctcaccgt actaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002538             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:20601:3543
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002538
VERSION     KCWK01002538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20601:3543"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68276.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          156 c          127 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggagatt tttatgtgca gtggtaccag caccttccag
      241 gaacggcccc cagactcctc atctatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggaacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag tttgattgct gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002539             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:7850:13148
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002539
VERSION     KCWK01002539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7850:13148"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68277.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           91 a          142 c          133 g          102 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtatc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtgctggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002540             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:8930:11808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002540
VERSION     KCWK01002540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8930:11808"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..450
                     /note="immunoglobulin light chain variable region"
     V_region        114..450
     V_segment       114..407
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68278.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       413..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           94 a          156 c          127 g          111 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaacatc ggggcgggtt attatgtatc ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattac tgctcagcat gggatagcag cctgagtatt aattacatct
      421 tcggtggtgg gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCWK01002541             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:20689:15616
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002541
VERSION     KCWK01002541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:20689:15616"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68279.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           81 a          164 c          115 g          115 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac gttggtggtt ctaactctgt ctcctggtac caacaacacc caggcagagc
      241 ccccaaactc atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct ggcctccagt ctgaggacga
      361 ggctgattat tactgttgtt cacattcaac cagtagtact tacgtcttcg gtcctgggac
      421 ccggctcacc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002542             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:8189:17785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002542
VERSION     KCWK01002542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8189:17785"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68280.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>484
                     /gene="IGLC"
BASE COUNT           90 a          160 c          126 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tcgggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca actcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct cccagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcggcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt ccccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01002543             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:24876:4017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002543
VERSION     KCWK01002543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24876:4017"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..431
                     /note="immunoglobulin light chain variable region"
     V_region        104..431
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68281.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       395..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          143 c          136 g          102 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt gaagttgtca actggtacca acagaagcca ccgcaggccc ctgtggtggt
      241 catctatgct gattatgaac ggccctcagg gatccctgag cgattctctg gctccaaatc
      301 agggaacacg gccaccctga ccatcagcgg agtcgcggcc ggggatgagg ctgactatta
      361 ctgtcaggtt tgggacattt atactgatca tccggtgttg ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002544             498 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:18107:17312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002544
VERSION     KCWK01002544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 498)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18107:17312"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..460
                     /note="immunoglobulin light chain variable region"
     V_region        130..460
     V_segment       130..423
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>432
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68282.1"
                     /translation="DYYCAAWDESLRGYIF"
     J_segment       424..460
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        461..>498
                     /gene="IGLC"
BASE COUNT          100 a          157 c          134 g          107 t
ORIGIN      
        1 acatggggag atttgggtga agcgcagctt cagctgtggg tacagaaggc aggactcagg
       61 acaatctcca gcatggcctg gttccctctc gtcctcaccc tcctcactca ctgcgcaggg
      121 tcctgggccc agtctgtgct gactcagcct ccctcagcgt ctgaggccgc caggaagagt
      181 gtcaccatct cctgttctgg gagcagctcc aacatcggaa gaaatagtgt atcctggtac
      241 cagcagctcc caggaacagc tcccaaaatc ctcatctatt atagtgatca acgagcctca
      301 ggtgtctctg accgattctc tggctccaag tctggcacgt cagccgccct ggccatcagc
      361 gggctccaga ccgaggatga ggctgattat tactgcgcag catgggatga aagcctgagg
      421 ggttacatct tcggtgctgg gacccggctc accgtcctag gtcagcccaa ggcttccccc
      481 acggtcactc tgttcccg
//
LOCUS       KCWK01002545             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:23649:13289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002545
VERSION     KCWK01002545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:23649:13289"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..392
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68283.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       394..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          150 c          124 g          107 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctcctct
       61 cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc tgacgcagcc
      121 gccctcagtg tctggggcgc ccgggcagag ggtcaccatc tcctgcactg ggagcagctc
      181 caacattgga ggttattatg tgcagtggta ccagcagctt ccaggaacgg cccccaaact
      241 cctcatctat gaaaatgata aacgaccctc aggggtttct gatcgattct ctggctccca
      301 gtctgattcc tcagcctccc tgaccatcac tggactccag tctgaggatg aggctgatta
      361 ttactgccag tcctatgaca gcagcttgag tgttgtgtta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002546             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:12672:10394
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002546
VERSION     KCWK01002546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12672:10394"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68284.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       403..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           88 a          157 c          120 g          112 t
ORIGIN      
        1 acatgggggg tggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc aagcctatgc tgactcagcc ggcctccctc
      121 tcagcatctc ctggagcatc agccagtctc acatgcacct tcagcggtgg catcaatgtt
      181 gctgtctacc acgtacactg gtaccagcag aagccaggga gtcccccccg gtttcttctg
      241 aggtacaaat cagactcaga taagggccag ggctctggag tccccagccg cttctctgga
      301 tccagtaatg tttcagcgaa cacagggatt ttacgcattt ctgggctcca gtctgaggat
      361 gaggctgact attactgtgc cattgggcac agcagcggtc cttacatctt cggtgctggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01002547             415 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:20914:2464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002547
VERSION     KCWK01002547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 415)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20914:2464"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..377
                     /note="immunoglobulin light chain variable region"
     V_region        86..377
     V_segment       86..340
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>349
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68285.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       343..377
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>415
                     /gene="IGLC"
BASE COUNT           77 a          133 c          108 g           97 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcag ctgcaccttg agcagtggcg tcaatgtggg
      121 tagttacagc gtattctggt accagcagaa gccagggagt cctccccggt accttctgta
      181 ctaccagtca gactcaagga aacaccaggg ctctggagtc cccagccgct tctctggatc
      241 caaagatgct tcagccaatg cagggctgtt actgatctct gggctccagt ctgaagatga
      301 ggctgactat tactgtgccc tatggcacag cagcgcttct tgcatcttcg gtggtgggac
      361 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002548             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:12360:5967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002548
VERSION     KCWK01002548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12360:5967"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..388
                     /note="immunoglobulin light chain variable region"
     V_region        58..388
     V_segment       58..351
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <313..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68286.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       352..388
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           74 a          143 c          109 g          100 t
ORIGIN      
        1 acatgggggt tccctctcgt cctcaccctc ctcactcact gtgcagggtc ctgggcccag
       61 tctgtgctga ctcagcctcc ctcagcgtct gaggccgccg ggaagagtgt ctccatctcc
      121 tgttctggaa gcagctccaa catcggaagt catagtgtct cctggtacca gcagctccca
      181 ggaacagctc ccaaactcct catctattat agtgatcaac gagcctcagg tgtctctgac
      241 cgattctctg gctctcagtc tggcacgtca gcctccctgg ccatcagtgg gctccagacc
      301 gaggatgagg ctgattatta ctgcgcagca tgggatgata gcctgagcgg ttacatcttc
      361 ggtgctggga cccggctcgc cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      421 ttcccg
//
LOCUS       KCWK01002549             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:12007:6935
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002549
VERSION     KCWK01002549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12007:6935"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68287.1"
                     /translation="DYFCQVWGSRSDHPIF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          148 c          137 g           92 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctggctcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta actatgtaca ctggtaccag cagaagccag ggcaggcccc tgtagagatc
      241 atctttgctg ataacaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggatcaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactatttc
      361 tgtcaggtgt ggggcagtcg tagtgatcat ccgatattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002550             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:23869:10030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002550
VERSION     KCWK01002550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:23869:10030"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68288.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          163 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtagcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002551             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:5117:15036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002551
VERSION     KCWK01002551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5117:15036"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68289.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          155 c          116 g          110 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggaacatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catacactgg taccaacaaa agtcagggag tcctccccgg tatcttctga
      241 gatacaaatc agactcagat aggggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tggtctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtga ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002552             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:24489:14078
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002552
VERSION     KCWK01002552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24489:14078"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68290.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       384..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           89 a          143 c          125 g          101 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagccgg ccaggatcac ctgctctgga gatgtattgc
      181 caaaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgta ttggtcatct
      241 ctgaggacac cgaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcagcaga cagtagtggt catggcttct tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002553             358 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:9474:11627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002553
VERSION     KCWK01002553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 358)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 358)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..358
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9474:11627"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..320
                     /note="immunoglobulin light chain variable region"
     V_region        9..320
     V_segment       9..285
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <248..>292
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68291.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       290..320
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        321..>358
                     /gene="IGLC"
BASE COUNT           72 a          111 c           89 g           86 t
ORIGIN      
        1 acatgggact ccctctgtgt ccgggtctcc tggacagtcg gtcaccatct cctgcactgg
       61 aaccagcagt gatattgggt attatcatgc tgtgtcttgg taccagcatc atccaggcaa
      121 agcccccaaa ctcatgattt atgaggtcaa taaacggccc gcaggggtct ctgatcgctt
      181 ctctggctcc aagtctggca acacggcctc cctgaccatc tctgggctcc agactgagga
      241 tgaggctgat tattactgca gctcatatgc aggcagcaac actttattct tcggaggagg
      301 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002554             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:11478:4649
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002554
VERSION     KCWK01002554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11478:4649"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..303
                     /note="immunoglobulin light chain variable region"
     V_region        8..303
     V_segment       8..263
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68292.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       266..303
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           74 a          103 c           88 g           76 t
ORIGIN      
        1 acatgggcag tctcacatgc accttcagcg gtggcatcaa tgttgctggc taccacatac
       61 actggtacca gcagaagcca gggagtcctc cccgatatct tctgagatac aaatcggact
      121 cagataaggg ccagggctct ggagtcccca gccgcttctc tggatccaaa gatgcttcag
      181 cgaacacagg gattttacgc atctctgggc tccagtctga ggatgaggct gactattact
      241 gtgccattgg acacagcagc ggtgattaca tcttcggtgc tgggacccgg ctcaccgtcc
      301 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01002555             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:11901:11942
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002555
VERSION     KCWK01002555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:11901:11942"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..387
                     /note="immunoglobulin light chain variable region"
     V_region        63..387
     V_segment       63..350
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <312..>359
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68293.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       351..387
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        388..>425
                     /gene="IGLC"
BASE COUNT           83 a          128 c          121 g           93 t
ORIGIN      
        1 acatgggggc ctggactttt ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg
       61 cctcctatga tctgactcag ccagcctcgg tgtcagtgtc cccgggacag acggccagga
      121 tcacctgtgg gggagacaat attggaagta aaaatgtgca ctggtaccag caggagccac
      181 cgcaggcccc tgtgttggtc atcttttatg ataacaaacg gccctcaggg atccctgagc
      241 gattctctgg ctccaaatca gggaacatcg ccaccctgac catcagcgag gccgaggccg
      301 gggatgaggc tgactattac tgtcagctgt gggacagtag tgttgatcat ggcttattcg
      361 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      421 tcccg
//
LOCUS       KCWK01002556             359 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:24120:17681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002556
VERSION     KCWK01002556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 359)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 359)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:24120:17681"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..321
                     /note="immunoglobulin light chain variable region"
     V_region        8..321
     V_segment       8..284
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <249..>293
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68294.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       286..321
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        322..>359
                     /gene="IGLC"
BASE COUNT           75 a          111 c           92 g           81 t
ORIGIN      
        1 acatggggga gccctcaatg actgtgtccc caggagggac agtcactctc acctgtgctt
       61 ccagcactgg agcagtcacc agtggtcact ctccacactg gttccagcag aaacctggac
      121 aagcccccaa gacactgatt tataatacaa actacagaca ctcctggact cctgcccggt
      181 tctcaggctc cctccttggg ggtaaagctg ccctgacact gtcaggtgcg cagcctgagg
      241 atgaggctga gtattattgt ttactgtact atagtggtgc tcagctgtta ttcggaggag
      301 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002557             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:22060:8790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002557
VERSION     KCWK01002557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22060:8790"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68295.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          161 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tgttaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 cattcctata ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggtcgattat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002558             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:10572:14728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002558
VERSION     KCWK01002558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:10572:14728"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..406
                     /note="immunoglobulin light chain variable region"
     V_region        88..406
     V_segment       88..374
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68296.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       375..406
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           88 a          140 c          119 g           97 t
ORIGIN      
        1 tcagaagcag agctctgggg tgtctccacc atggcctgga ctcctctctg gctcaccctc
       61 ctcagtcttt gcacaggttc tatggtttct tctgagctga ctcaggaccc tgcagtgtct
      121 gtggccttgg ggcagacagt caggattacc tgccaaggag acagcctcag aagctcttat
      181 gcaaactggt accaacagag gccaggccag gcccctgtgc tggtcgtcta tggtaacaac
      241 taccggccct cagggatccc agagcgattc tctggctcct actcccgaaa cacagcttcc
      301 ttgaccatca ctggggctca ggtggaagat gaggctgact attactgtga ctcctgggac
      361 agcagcggaa cccaattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct
      421 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002559             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:6758:19566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002559
VERSION     KCWK01002559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6758:19566"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68297.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          163 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagcaggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002560             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:18858:7863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002560
VERSION     KCWK01002560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18858:7863"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68298.1"
                     /translation="DYFCQVWGSRSDRPIF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          147 c          141 g           91 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gactctgcga cctcctatga gctggctcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta actatgtgca ctggtaccag cagaagccag ggcaggcccc tgtagagatc
      241 atctttgctg ataacaaacg gccctcaggg atccctgagc gattctctgg ctccagctca
      301 gggatcaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactatttc
      361 tgtcaggtgt ggggcagtcg tagtgatcgt ccgatattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002561             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:18628:18134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002561
VERSION     KCWK01002561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18628:18134"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68299.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           96 a          157 c          120 g          109 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcac ctccaacatc ggaagcaata atgtatcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcttt tattataatg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctcttgctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgataacct gagcggctac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01002562             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:28454:7413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002562
VERSION     KCWK01002562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:28454:7413"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..390
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68300.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       395..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT          105 a          137 c          124 g          101 t
ORIGIN      
        1 acatgggggg ctgtggttct aggaggaaga gctctgggtg tctcaccatg acctggacca
       61 ctgttctgct cccctttctc actctctgca caggctctga ggcctcctat gagctgacac
      121 agccaccctc agtgtcagtg tccccaggac agacggccag gatcacctgc tctggagaaa
      181 tactggcaaa aaaatatact cagtggttcc agcagcagcc aggccaggcc cctttcctgg
      241 tgatatataa agacagtgag aggccctcag ggatccctgg gcgattctct agctccagtt
      301 cagggacaac aattaccttg accatcagtg gggcccaggc agaagatgag gctgactatt
      361 actgtcaatc agtagacagc agtggaaatc ttccgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002563             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:22389:8423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002563
VERSION     KCWK01002563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22389:8423"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68301.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       402..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           85 a          161 c          124 g          106 t
ORIGIN      
        1 acatggggtg gggtctcagg aggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catcccctgc actggaacca
      181 acagtgacat cggtgattat gactttgtct cctggtacca acaacatcca ggcacagccc
      241 ccagactcgt gatttatgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg cctccagcct gaggacgagg
      361 ctgattatta ctgcagctca tatgcaggca gcgacacttt cgtgttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002564             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12401:9009
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002564
VERSION     KCWK01002564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12401:9009"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68302.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          140 c          137 g          103 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagtgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002565             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:18403:9618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002565
VERSION     KCWK01002565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18403:9618"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..401
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68303.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       406..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           90 a          155 c          119 g          110 t
ORIGIN      
        1 acatggggct gggatctcag gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccccgact
      121 cagactccct ctgtgtccgg gtctcctgga cagtcggtca ccatctcctg cagtggaacc
      181 agcagtgata ttgggtatta tcatgctgtg tcttggtacc aacatcgtcc aggcaaagcc
      241 cccaaactca tgatttatga ggtcaataaa cggcccgcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccagac tgaggatgaa
      361 gctgattatt actgcagctc atatgcaggc agcaacactt tattcttcgg acgagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002566             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:6182:12081
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002566
VERSION     KCWK01002566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6182:12081"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68304.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          142 c          136 g          102 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaggccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg cccccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002567             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:12285:13606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002567
VERSION     KCWK01002567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12285:13606"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..423
                     /note="immunoglobulin light chain variable region"
     V_region        103..423
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68305.1"
                     /translation="DYFCQVWDSGSDHYIF"
     J_segment       390..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>465
                     /gene="IGLC"
BASE COUNT           86 a          149 c          132 g           98 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gttgactcag
      121 ccaccctcgg tgtcagcggc ctctggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta catatgtgca ctggtaccag cagaagccac cacaggcccc tgtgcaggtc
      241 atctttgctg atagcaaacg gccctcaggg gtccctgacc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactatttc
      361 tgtcaggtgt gggacagtgg tagtgatcat tacatcttcg gtgttgggac ccggctcacc
      421 gtcttaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002568             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:15469:2607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002568
VERSION     KCWK01002568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15469:2607"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68306.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          160 c          118 g          109 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctctgcat ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctgcct accacataca ctggtaccag cagaagccag ggagtcctcc ccggtatctt
      241 ctgaggttca aatcagactc agataaggac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcctcagc gaacacaggg attttacgca tctctgggat ccagtctgag
      361 gatgaggctg actactactg tgccattggg cacagcagcg gtgattacat cttcggtgct
      421 gggacccgcc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002569             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:3888:7054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002569
VERSION     KCWK01002569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:3888:7054"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68307.1"
                     /translation="DYFCQVWDSGSDHYIF"
     J_segment       389..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>464
                     /gene="IGLC"
BASE COUNT           86 a          149 c          132 g           97 t
ORIGIN      
        1 acatggggct gggtccagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag gctctgcgac ctcctatgag ttgactcagc
      121 caccctcggt gtcagcggcc tctggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaactac atatgtgcac tggtaccagc agaagccacc acaggcccct gtgcaggtca
      241 tctttgctga tagcaaacgg ccctcagggg tccctgaccg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactatttct
      361 gtcaggtgtg ggacagtggt agtgatcatt acatcttcgg tgttgggacc cggctcaccg
      421 tcttaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01002570             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:13500:19070
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002570
VERSION     KCWK01002570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:13500:19070"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..252
                     /note="immunoglobulin light chain variable region"
     V_region        8..252
     V_segment       8..215
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <180..>224
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68308.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       218..252
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        253..>290
                     /gene="IGLC"
BASE COUNT           57 a           92 c           75 g           66 t
ORIGIN      
        1 acatgggatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt ctgtactacc
       61 agtcagactc aaggaaacac cagggctctg gagtccccag ccgcttctct ggatccaaag
      121 atgcttcagc caatgcaggg ctgttactga tctctgggct ccagtctgaa gatgaggctg
      181 actattactg tgccctatgg cacagcagcg cttcttgcat cttcggtggt gggacccggc
      241 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002571             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:16951:4183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002571
VERSION     KCWK01002571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16951:4183"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..404
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68309.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          157 c          123 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgcccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagtagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002572             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:17548:5883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002572
VERSION     KCWK01002572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17548:5883"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68310.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          161 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggcta caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002573             318 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:15869:6614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002573
VERSION     KCWK01002573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 318)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15869:6614"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..280
                     /note="immunoglobulin light chain variable region"
     V_region        8..280
     V_segment       8..240
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>252
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68311.1"
                     /translation="DYYRQVWDIYIDHPVLF"
     J_segment       244..280
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        281..>318
                     /gene="IGLC"
BASE COUNT           67 a           87 c           95 g           69 t
ORIGIN      
        1 acatggggga tcacctgtgg gggagacaat attggaagtg aagttgtcaa ctggtaccag
       61 cagaagccac cgcaggcccc tgtggtggtc atctatgctg attatgaacg gccctcaggg
      121 atccctgagc gattctctgg ctccaaatca gggaacacgg ccaccctgac catcagcgga
      181 gtcgaggccg gggatgaggc tgactattac cgtcaggttt gggacattta tattgatcat
      241 ccggtgttat tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc
      301 tcggtcactc tcttcccg
//
LOCUS       KCWK01002574             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10065:18433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002574
VERSION     KCWK01002574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10065:18433"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..433
                     /note="immunoglobulin light chain variable region"
     V_region        85..433
     V_segment       85..396
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68312.1"
                     /translation="DYYCHVYDSGANVLF"
     J_segment       397..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           88 a          159 c          115 g          109 t
ORIGIN      
        1 acatggggag aggtagccgt gtccaccatg gccctgactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctcccagcct gtgctgactc agccaccctc cctgtctgca
      121 tccccgggag catcggccag actcccctgc actctgagca gtgacctcag tgttggtggt
      181 aaaaacatgt actggtacca gcagaagcca gggagcgctc ccaggttatt cctgttctac
      241 tactccgact cagacaacca gttgggacct ggggtcccca atcgagtctc tggctccaag
      301 gagacctcaa ctaacacagc gtttttgctc atctctgggc tccagcctga ggacgaggcc
      361 gattattact gtcacgtata tgacagtggt gctaatgtgt tattcggcgg agggacccga
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002575             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10990:7993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002575
VERSION     KCWK01002575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10990:7993"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68313.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          162 c          110 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtacttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002576             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:22040:19465
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002576
VERSION     KCWK01002576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:22040:19465"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68314.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       410..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          153 c          131 g          110 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac atcggggcgg gtttttatgt atcctggtac cagcagttcc
      241 caggaaaagc ccccaagctc ctcatctttg aaaataacaa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggttcct cagcctccct gaccatcact ggactccaat
      361 ctgaggatga ggctgattat tattgttcat catgggaaag cagcctgaat tgggtattcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002577             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:10839:17596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002577
VERSION     KCWK01002577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10839:17596"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68315.1"
                     /translation="DYYCQTWDIGIWIF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           85 a          165 c          121 g          100 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggc
      181 cactacagct acaccatcgc atggcatcag cagcaacaag ggaaggcccc tcggttcttg
      241 atgtggctta agagtgatgg cagccacacc aagggggacg gggtccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggacatt ggcatttgga tattcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002578             332 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:15700:15217
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002578
VERSION     KCWK01002578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 332)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15700:15217"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..294
                     /note="immunoglobulin light chain variable region"
     V_region        7..294
     V_segment       7..257
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <219..>266
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68316.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       258..294
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>332
                     /gene="IGLC"
BASE COUNT           72 a          103 c           82 g           75 t
ORIGIN      
        1 acatggggaa gagtgtcacc atctcctgtt ctggaagcag ctccaacatc ggaagtaata
       61 atgtgtcctg gtaccagcac ctcccaggaa cagctcccaa actcctcatc tactataatg
      121 atcaacgagg ctcaggtgtc tctgaccgat tctctggctc caagtctggc acgtcagcct
      181 ccctggccat cagtgggctc cagaccgagg atgaggctga ttattactgc gcagcgtggg
      241 atgatagact gagcagttac atcttcgctg ctgggacccg gctcaccgtc ctaggtcagc
      301 ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002579             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:6686:12773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002579
VERSION     KCWK01002579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6686:12773"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..435
                     /note="immunoglobulin light chain variable region"
     V_region        93..435
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68317.1"
                     /translation="DYYCAIGLSSGYIF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>441
                     /gene="IGLC"
BASE COUNT           87 a          141 c          112 g          101 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgtac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacacacac tggtaccagc agaagccagg gaggcctccc cggtatcttc
      241 tgagatacaa atcagactca gataggggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgtttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc tcagcagcgg ttacatcttc ggtactggga
      421 cccggctcac cgtcccaggt c
//
LOCUS       KCWK01002580             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:9218:2825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002580
VERSION     KCWK01002580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9218:2825"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68318.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       400..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           83 a          161 c          126 g           98 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtggtgac tcagtcgtcc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cggtgggcac
      181 agcgactaca ccatcgcatg gcatcagcag cagcaaggga aggcccctcg gtatttgatg
      241 tggcttaaaa gtgatggcag ccacagcaag ggggacggga tccctgatcg cttctccggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggagactggc attcaggtgt tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002581             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:27281:12326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002581
VERSION     KCWK01002581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:27281:12326"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68319.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtgacc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002582             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:15494:12910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002582
VERSION     KCWK01002582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15494:12910"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68320.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          160 c          116 g          107 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatcccc tggaacatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgtctaccc catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 catacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ctcagcgaac acagggattt tacgcatctc tggcctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtga ttacatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002583             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:2313:10299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002583
VERSION     KCWK01002583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:2313:10299"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..385
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68321.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       389..421
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           93 a          142 c          131 g           93 t
ORIGIN      
        1 acatgggggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg gacccttctc
       61 ctcctcggcc tcctcgctta ctgcacaggc tctgcgacct cctatgaatt gactcagtca
      121 ccctcagtgt cagcggcctc aggacagccg gccaggatca cctgtggggg agacaacatt
      181 ggaactaaaa ctgtgcactg gtaccaacag aagccaccgc agggccctgt attggtcatc
      241 tttgctgata gtagacggcc ctcagggatc cctgagcgat tctctggctc caactcaggg
      301 aacaccgcca ccctgaccat cagcagggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag taaatggata ttcggcgggg ggacccggct aaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002584             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15459:12090
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002584
VERSION     KCWK01002584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15459:12090"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68322.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       390..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           86 a          142 c          135 g           99 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcgattt cagtgtcccc aggacagacg gccagggtca cctgtggggg agacaacatc
      181 ggaggtgaag ttgtgaattg gtaccagcag aagccaccgc aggcccctgt gttggtcatc
      241 tatgctgata gcgagcggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacgcggcca ccctgaccat cagcggggtc gaggccggag atgaggctga ctattactgt
      361 caggtgtggg accttaatag tcatcatctc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002585             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:20137:4011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002585
VERSION     KCWK01002585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20137:4011"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..336
                     /note="immunoglobulin light chain variable region"
     V_region        8..336
     V_segment       8..299
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68323.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       300..336
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           80 a          121 c           89 g           84 t
ORIGIN      
        1 acatgggggc ctccctctca gcaactcctg gagcatcagc cagtctcaca tgcaccttca
       61 gcggtggcat caatgttgtt gcctaccaca tacactggta ccagcagaag ccagggagtc
      121 ccccccggta tcttctgagt tacgaatcag actcagataa gggccagggc tctggagtcc
      181 ccagccgctt ctctggatcc aaaaatgctt caacaaacac aggcatttta cacatctctg
      241 ggctccagtc tgaggatgag gctgactatt tctgtgccat tggacacagc agcggtcctt
      301 acatcttcgg tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg
      361 tcactctgtt cccg
//
LOCUS       KCWK01002586             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:19194:12370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002586
VERSION     KCWK01002586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19194:12370"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68324.1"
                     /translation="DYYCAIGHYSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          158 c          115 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cgatatcttc
      241 tgagatacaa atcggactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctggcctc cagtctgagg
      361 atgaggctga ctattactgt gccattggac actacagcgg tgattacatc ttcggtgctg
      421 ggacccgact caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002587             295 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:25981:16013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002587
VERSION     KCWK01002587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 295)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25981:16013"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..257
                     /note="immunoglobulin light chain variable region"
     V_region        115..257
     V_segment       115..220
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>229
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68325.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       221..257
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>295
                     /gene="IGLC"
BASE COUNT           48 a          105 c           72 g           70 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgctt
      121 ctcaggctcc agctccgggg ctgagcgcta cctcaccatc tccaacctcc agtctgagga
      181 tgaggctgat tattactgtc agacctggga tattggcatt tgggtattcg gcggagggac
      241 ccggctaatc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002588             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:20833:1970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002588
VERSION     KCWK01002588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20833:1970"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..432
                     /note="immunoglobulin light chain variable region"
     V_region        100..432
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68326.1"
                     /translation="DYYCQTWDTGIVFF"
     J_segment       397..432
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>471
                     /gene="IGLC"
BASE COUNT           90 a          164 c          119 g           98 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaaactca cctgcactct gaacagtggg
      181 cacagcagct acaccatcgc atggcatcag cagcagaaag ggaaggcccc ccggtacttg
      241 atgtggctta aaactgatgg cagccataac aacggggacg ggatccctga tcgcttcgca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatact ggcattgtgt tcttcggagg agggacccgg
      421 ctgaccgtcc taagtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002589             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:20905:4539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002589
VERSION     KCWK01002589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20905:4539"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68327.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          161 c          124 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actgctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002590             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:14290:23806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002590
VERSION     KCWK01002590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14290:23806"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68328.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          154 c          122 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcacca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002591             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:26004:9104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002591
VERSION     KCWK01002591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:26004:9104"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..431
                     /note="immunoglobulin light chain variable region"
     V_region        107..431
     V_segment       107..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68329.1"
                     /translation="YYSCNSYAGSGVYIF"
     J_segment       394..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           84 a          154 c          117 g          114 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcattgga tattataatg ctgtgtcttg gtaccaacaa catccaggca aagcccccaa
      241 actcatgatt tatgaggtca gtaagcggcc ctcaggggtc tctgatcgct tctctggctc
      301 caagtctggc aacacggcct ccctatccat ctctgggctc caggctgagg acgaggctta
      361 ttattcttgc aactcatatg caggtagtgg tgtttacatc ttcggtgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002592             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:7148:12509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002592
VERSION     KCWK01002592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7148:12509"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68330.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          156 c          123 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca ttagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002593             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:16670:10715
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002593
VERSION     KCWK01002593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16670:10715"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68331.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          161 c          111 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgttgccta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagttacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaaa tgcttcaaca aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002594             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:28688:9411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002594
VERSION     KCWK01002594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:28688:9411"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68332.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          154 c          126 g          110 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcaag tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga taaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg aggggttaca tcttcggtgc
      421 tgggacccgg ctcgccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01002595             318 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:12423:6253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002595
VERSION     KCWK01002595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 318)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12423:6253"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..280
                     /note="immunoglobulin light chain variable region"
     V_region        7..280
     V_segment       7..243
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>252
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68333.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       244..280
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        281..>318
                     /gene="IGLC"
BASE COUNT           70 a           99 c           77 g           72 t
ORIGIN      
        1 acatggggtg gcatcaatgt tgctgcctac cacatacact ggtaccagca gaagccaggg
       61 agtccccccc ggtatcttct gagttacaaa tcagactcag ataagggcca gggctctgga
      121 gtccccagcc gcttctctgg atccaaaaat gcttcaacaa acacaggcat tttacacatc
      181 tctgggctcc agtctgagga tgaggctgac tatttctgtg ccattggaca cagcagcggt
      241 ccttacatct tcggtgctgg gacccggctc accgtcctag gtcagcccaa ggcttccccc
      301 acggtcactc tgttcccg
//
LOCUS       KCWK01002596             505 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:5105:6458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002596
VERSION     KCWK01002596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 505)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:5105:6458"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    137..467
                     /note="immunoglobulin light chain variable region"
     V_region        137..467
     V_segment       137..430
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <392..>439
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68334.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       431..467
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        468..>505
                     /gene="IGLC"
BASE COUNT           96 a          160 c          137 g          112 t
ORIGIN      
        1 acatggggga gggagagatt tgggtgaagc gcagcttcag ctgtgggtac agaaggcagg
       61 actcaggaca atctccagca tggcctggtt ccctctcgtc ctcaccctcc tcactcactg
      121 tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc tcagcgtctg aggccgccag
      181 gaagagtgtc tccatctcct gttcgggaag cagctccaac atcggaagtc atagtgtctc
      241 ctggtaccag caactcccag gaacagctcc caaactcctc atctattata gtgatcaacg
      301 agcctcaggt gtctctgacc gattctctgg ctcccagtct ggcacgtcag cctccctggc
      361 catcagtggg ctccagaccg aggatgaggc tgattattac tgcgcggcat gggatgatag
      421 cctgagcggt tacatcttcg gtgctgggac ccggctcacc gtcctaggtc agcccaaggc
      481 ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002597             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:20920:17258
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002597
VERSION     KCWK01002597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20920:17258"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68335.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           98 a          160 c          112 g          110 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcaa ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgttgcct accacataca ctggtaccag cagaagccag ggagtccccc ccggtatctt
      241 ctgagttaca aatcagactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaaa atggttcaac aaacacaggc attttacaca tctctgggct ccagtctgag
      361 gatgaggctg actatttctg tgccattgga cacagcagcg gtccttacat cttcggtact
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002598             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:19893:2767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002598
VERSION     KCWK01002598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19893:2767"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..258
                     /note="immunoglobulin light chain variable region"
     V_region        8..258
     V_segment       8..221
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <183..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68336.1"
                     /translation="DYYCQVWDSTSDHYIF"
     J_segment       222..258
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           62 a           93 c           79 g           62 t
ORIGIN      
        1 acatgggcaa cattggaact acgtttgtcc actggtacca gcagaatcca ccgcaggccc
       61 ctgtgcaggt catctttgcg gataacaaac ggccctcagg gatccctgaa cgattctctg
      121 gctccaactc agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg
      181 ctgactatta ctgtcaggtg tgggacagta ctagtgatca ttacatcttc ggtggtggga
      241 cccgcctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002599             453 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:18698:19511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002599
VERSION     KCWK01002599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 453)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18698:19511"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..415
                     /note="immunoglobulin light chain variable region"
     V_region        91..415
     V_segment       91..372
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68337.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       381..415
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>453
                     /gene="IGLC"
BASE COUNT           85 a          148 c          131 g           89 t
ORIGIN      
        1 acatggggag gcagcattga cggtgcctca gccatggcct ggacccttct cctcctcggc
       61 ctcctcgctc actgcacagg ctctgcgacc tcctatgagc tgactcagcc accctcggtg
      121 tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat tggaactaag
      181 tatgtgcact ggtaccagca gaagccaccg caggcccctg tgttggtcat ctatgctgat
      241 accagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg gaacaccgcc
      301 accctgacca tcagcggggt cgaggccggg tatgaggctg actatttctg tcaggtgtgg
      361 gacgatagca gtgatcatcc ggtattcggc ggagggaccc ggctgaccgt cctaggtcag
      421 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002600             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:8967:12572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002600
VERSION     KCWK01002600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8967:12572"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68338.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       401..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           96 a          153 c          111 g          116 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcatctcc tggagcatca gccagactca cctgcacctt gaacagtggc atcagtgttg
      181 ctaattacag gatattctgg taccaccaga agccagggag tcctccccgg tatcttctga
      241 actaccacac agactcagat attcatcagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcagggattt tactcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtatg atttggcaca acaatgctta ttgggttttc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002601             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:20997:18552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002601
VERSION     KCWK01002601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20997:18552"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68339.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          162 c          108 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt tagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccaacaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002602             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:4793:11337
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002602
VERSION     KCWK01002602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:4793:11337"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68340.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       404..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          152 c          117 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcttc tcctggagca tcagccagac tcacctgcac cttgagcagt ggcatcagtg
      181 ttggtactta caggatattc tggtaccagc agaggccagg gagtcctccc cggtatcttc
      241 tgaaccacca cacagactca gataaacatc agggctctgg agtccccagc cgcttctctg
      301 gatcaaaaga tgcttcggcc aatgcaggga ttttgctcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttatgtgtta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002603             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:18493:4027
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002603
VERSION     KCWK01002603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18493:4027"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68341.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          150 c          134 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta aatatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
      241 atctatgctg ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcaccggg gtcgaggccg ggtatgaggc tgactatttc
      361 tgtcaggttt gggacgatag tagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002604             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:16756:12699
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002604
VERSION     KCWK01002604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16756:12699"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68342.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          157 c          127 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattac tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002605             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:18268:3816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002605
VERSION     KCWK01002605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18268:3816"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..350
                     /note="immunoglobulin light chain variable region"
     V_region        20..350
     V_segment       20..311
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <278..>322
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68343.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       320..350
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        351..>388
                     /gene="IGLC"
BASE COUNT           76 a          127 c           98 g           87 t
ORIGIN      
        1 acatgggggg tcctgggccc agtctgtgct gacgcagccg ccctcagcat ctggggcccc
       61 cggacagagg gtcaccatct cctgcattag cggcagctcc aacatcgggg cggcttatta
      121 tgtatcctgg taccaacagt tcccaggaac agcccccaaa ctcctcatct ttgaaaataa
      181 taagcgaccc tcaggggttt ctgaccgatt ctctggctcc aagtctggtc cctcagcctc
      241 cctgaccatc actggactcc aatctgacga tgaggctgat tattactgtt tagcatggga
      301 taccagcctg aattggatct tcggcggagg gacccggctg accgtcctag gtcagcccaa
      361 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002606             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:27003:10092
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002606
VERSION     KCWK01002606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:27003:10092"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68344.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          151 c          116 g          107 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactccca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002607             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:9772:12147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002607
VERSION     KCWK01002607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:9772:12147"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..449
                     /note="immunoglobulin light chain variable region"
     V_region        101..449
     V_segment       101..412
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68345.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           89 a          164 c          122 g          112 t
ORIGIN      
        1 acatggggct gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagtagtga
      181 cctcagtgtt ggtagtaaaa acatctactg gtaccagctg aagccaggga gcgctcccag
      241 gtcattcctg tactactact ccgactcaga caagcagctg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt attactgtca ggtctatgac agtagtgcta atgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01002608             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17028:9799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002608
VERSION     KCWK01002608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17028:9799"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68346.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          153 c          121 g          114 t
ORIGIN      
        1 acatgggggc tgggatctca gcaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggttcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt ataacgctgt gtcttggtac caacagcatc caggcaaagc
      241 ccccaaactc ataatttttg acgtcattaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccggg ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagaaataat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002609             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:14117:21384
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002609
VERSION     KCWK01002609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14117:21384"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68347.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          164 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca aacagctggg acctggggtc cccaatcgcg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002610             496 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:20058:15523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002610
VERSION     KCWK01002610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 496)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20058:15523"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..458
                     /note="immunoglobulin light chain variable region"
     V_region        110..458
     V_segment       110..421
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>430
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68348.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       422..458
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        459..>496
                     /gene="IGLC"
BASE COUNT           92 a          171 c          124 g          109 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcca ccctccctgt ctgcgtcccc gggagcatcg gccagactcc cctgcaccct
      181 gaccagtgac ctcagcgttg gtagtaaaaa catgtattgg taccagcaga agccagggag
      241 cgctcccagg tcattcctct actactactc cgactcagac aagcagctgg gacctggggt
      301 ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc
      361 tgggctccag cctgaggacg aggccgacta ttactgtcag gtgtatgaca gtagtgctaa
      421 tgtgttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      481 ggtcactctc ttcccg
//
LOCUS       KCWK01002611             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20810:13292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002611
VERSION     KCWK01002611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20810:13292"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68349.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          156 c          123 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ttctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002612             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:14039:13939
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002612
VERSION     KCWK01002612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14039:13939"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..409
                     /note="immunoglobulin light chain variable region"
     V_region        85..409
     V_segment       85..371
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68350.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       373..409
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           88 a          143 c          121 g           95 t
ORIGIN      
        1 acatggggca ttgacggtgc ctcagccatg gcctggactt ttctcctcct cggcctcctt
       61 gcttactgca caggctctgc ggcctcctat gatctgactc agccaccctc ggtgtcagtg
      121 tccccaggac agacggccag gatcacctgt gggggagaca acattggaag tcaaagtgtg
      181 cactggtacc agcacaagcc accgcaggcc cctgtactgg tcatctttta ttataccgaa
      241 cggccctcag gaatccctga gcgattctct ggctccaaat cagggaacac cgccaccctg
      301 accatcagcg gggtcgaggc cggggatgag gctgactatt actgtcaggt gtgggacaca
      361 actattgatc acggcttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002613             326 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:11401:12538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002613
VERSION     KCWK01002613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 326)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:11401:12538"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..286
                     /note="immunoglobulin light chain variable region"
     V_region        8..286
     V_segment       8..252
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>260
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68351.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       253..286
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        287..>326
                     /gene="IGLC"
BASE COUNT           60 a          108 c           76 g           82 t
ORIGIN      
        1 acatgggggt caccatctcc tgcactggaa ccagcagtga cgttggtggt tctaactctg
       61 tctcctggta ccaacaacac ccaggcagag cccccaaact catgattttt ggtgtcaata
      121 atcggccctc tggggtctct gaccgcttct ctggctccaa gtctggcaac acggcctccc
      181 tgaccatctc tggcctccag tctgaggacg aggctgatta ttactgttgt tcacattcaa
      241 ccagtagtac ttacgtcttc ggtcctggga cccggctcac cgtcctgggt cagcccaagg
      301 cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002614             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:21388:18539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002614
VERSION     KCWK01002614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21388:18539"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68352.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          160 c          111 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggaaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002615             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:14660:9420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002615
VERSION     KCWK01002615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14660:9420"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68353.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           87 a          153 c          122 g          107 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtctccatc tcctgttctg gaagcagctc
      181 caacatcgga agtcatagtg tctcctggta ccagcagctc ccaggaacag ctcccaaact
      241 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctctca
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcatgggatg atagtctgag cggttacatc ttcggcgctg ggacccggct
      421 cgccgtccta ggtcagtcca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002616             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:9173:8658
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002616
VERSION     KCWK01002616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9173:8658"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..401
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68354.1"
                     /translation="DYYCAAWDDSLRSYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          155 c          123 g          108 t
ORIGIN      
        1 acatgggggc ttcagctgtg gttacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcagc ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct
      181 ggaagcagct ccaacatcgg aagtaataat gtgtcctggt accagcacct cccaggaaca
      241 gctcccaaac tcctcatcta ctataatgat caacgaggct caggtgtctc tgaccgattc
      301 tctggctcca agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat
      361 gaggctgatt attactgcgc agcgtgggat gatagcctga ggagttacat cttcgctgct
      421 gggacccggg tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002617             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:14407:12800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002617
VERSION     KCWK01002617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14407:12800"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..385
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68355.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       387..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           84 a          148 c          124 g          106 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gcatctgggg cccccgggca gagggttacc atctcctgca ctgggagcag ctccaacatc
      181 ggggcgggtt tttatgtgtc ctggtaccag cagttccctg gaacagcccc caaactcctc
      241 atctttgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggttcctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgctcatcat gggaaagcag cctgaattgg gttttcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002618             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20086:11184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002618
VERSION     KCWK01002618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20086:11184"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..274
                     /note="immunoglobulin light chain variable region"
     V_region        8..274
     V_segment       8..238
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>246
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68356.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       242..274
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        275..>312
                     /gene="IGLC"
BASE COUNT           69 a           88 c           93 g           62 t
ORIGIN      
        1 acatggggga tcacctgtgg gggagacaac attggaacta aaactgtgca ctggtaccaa
       61 cagaagccac cgcagggccc tgtattggtc atctttgctg atagtagacg gccctcaggg
      121 atccctgagc gattctctgg ctccaactca gggaacaccg ccaccctgac catcagcagg
      181 gtcgaggccg gggatgaggc tgactattac tgtcaggtgt gggacagtag tagtaaatgg
      241 atattcggcg gggggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      301 actctcttcc cg
//
LOCUS       KCWK01002619             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:19572:17480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002619
VERSION     KCWK01002619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:19572:17480"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68357.1"
                     /translation="DYYCQSSDSSANHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          136 c          122 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagac ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gtcaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc agtggttcca acagaagcca ggccaggccc ctgtgttggt
      241 gatatataaa gacaatgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca tcggacagca gtgctaatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002620             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:9692:14399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002620
VERSION     KCWK01002620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:9692:14399"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68358.1"
                     /translation="AYYCQVWDGDSDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          148 c          129 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gactctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcaacggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaagccag cgcaggcccc tatgcaggtc
      241 atctatgctg ataacaaacg gccctcaggg atctctgaga gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctattac
      361 tgtcaggtgt gggacggtga tagtgatcat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002621             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:3475:8948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002621
VERSION     KCWK01002621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:3475:8948"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..411
                     /note="immunoglobulin light chain variable region"
     V_region        63..411
     V_segment       63..374
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68359.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       375..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           86 a          154 c          104 g          105 t
ORIGIN      
        1 acatgggggc ctggactcct ctcctcctcc tgctcctctc tcactgcaca ggttccctct
       61 ccaagcctat gctgactcag ccggcctccc tctcagcatc tcctggagca tcagccagtc
      121 tcacatgcac cttcagcggt ggcatcaatg ttgttgccta ccacatacac tggtaccagc
      181 agaagccagg gagtcccccc cggtatcttc tgaggtacaa atcagactca gataagagcc
      241 agggcgctgg agtccccagt cgcttctctg gatccaataa tgcttcagcg aacacaggga
      301 ttttacgcat ctctggcctc cagtctgagg atgaggctga ctattactgt gccattgggc
      361 acagcagcgg tccttacatc ttcggtgctg ggacccgtct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002622             495 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:16793:12387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002622
VERSION     KCWK01002622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 495)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16793:12387"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..454
                     /note="immunoglobulin light chain variable region"
     V_region        109..454
     V_segment       109..419
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68360.1"
                     /translation="DYYCQVYDSRANTLF"
     J_segment       423..454
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>495
                     /gene="IGLC"
BASE COUNT           94 a          172 c          123 g          106 t
ORIGIN      
        1 acatgggggc ccaaccctgg gtctgtggcc tcagaggtag ccgtgtccac catggccctg
       61 actcctctcc tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg
      121 actcagccac cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg
      181 agcactgacc tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc
      241 gctcccaggt tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc
      301 cccaatcgag tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct
      361 gggctccagc ctgaggacga ggccgattat tactgtcagg tctatgacag tagagccaac
      421 acgttattcg gaggagggac ccggctgacc gtcccaggtc agcccaaggc tgccccctcg
      481 gtcactctct tcccg
//
LOCUS       KCWK01002623             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:17412:18228
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002623
VERSION     KCWK01002623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17412:18228"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..413
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68361.1"
                     /translation="DYYCAAWDDSLRSYIF"
     J_segment       417..454
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           97 a          157 c          130 g          108 t
ORIGIN      
        1 acatgggggg gtgaagcgca gcttcagctg tgggtacaga aggcaggact caggacaatc
       61 tccagcatgg cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg
      121 gcccagtctg tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc
      181 atctcctgtt ctggaagcag ctccaacatc ggaagtaata atgtgtcctg gtaccagcac
      241 ctcccaggaa cagctcccaa actcctcatc tactataatg atcaacgagg ctcaggtgtc
      301 tctgaccgat tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc
      361 cagaccgagg atgaggctga ttattactgc gcagcgtggg atgatagcct gaggagttac
      421 atcttcgctg ctgggacccg ggtcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCWK01002624             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:17536:18682
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002624
VERSION     KCWK01002624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17536:18682"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68362.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           98 a          143 c          122 g           97 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaagaatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tccagatcat
      241 ctatgaggac agtaaacggc cctctgggat ccctgagaga atcgctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 tttctcaaca gacaccagtg gtaatcgggt attcggcgga gggacccgtc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002625             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:5052:17183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002625
VERSION     KCWK01002625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:5052:17183"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68363.1"
                     /translation="DYYCHVYDSNTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          161 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca ggctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaagc atctactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaattcc gactcagaca agcagatggg acctggggtc cccagtcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagg
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag taacactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002626             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:25901:11824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002626
VERSION     KCWK01002626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25901:11824"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..295
                     /note="immunoglobulin light chain variable region"
     V_region        7..295
     V_segment       7..256
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <220..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68364.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       258..295
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        296..>333
                     /gene="IGLC"
BASE COUNT           68 a           99 c           86 g           80 t
ORIGIN      
        1 acatgggggc agagggtcac catctcctgc actgggagca gctccaacat tggaggttat
       61 tatgtgcagt ggtaccagca gcttccaggg acggccccca aactcctcat ctatgaaaat
      121 gataaacgac cctcaggggt ttctgatcga ttctctggct cccagtctga ttcctcagcc
      181 tccctgacca tcactggact ccagtctgag gatgaggctg attattactg ccagtcctat
      241 gacagcagct tgagtgttgt gttattcgga ggagggaccc ggctgaccgt cctaggtcag
      301 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002627             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:19772:6448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002627
VERSION     KCWK01002627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19772:6448"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68365.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          162 c          120 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt atcagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaagacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002628             360 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15250:7013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002628
VERSION     KCWK01002628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 360)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 360)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..360
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15250:7013"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..322
                     /note="immunoglobulin light chain variable region"
     V_region        8..322
     V_segment       8..285
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <253..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68366.1"
                     /translation="DYYCQSHDTSSVFF"
     J_segment       286..322
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>360
                     /gene="IGLC"
BASE COUNT           66 a          122 c           94 g           78 t
ORIGIN      
        1 acatgggagc cccattctgt gtcggggtct ccggggcaga cggtcaccat ctcctgcacc
       61 cgcagcagtg gcagcattga caacagtttt gtgtactggt accagcagcg gccgggcagc
      121 gcccccacca ctgtgattta cgcagataac caaagaccct ctggggtccc tgatcggttc
      181 tctggctcca tcgacagctc ctccaactct gcctccctca ccatctctgg actgaagtct
      241 gaggacgagg ctgactacta ctgtcagtct catgacacca gcagtgtgtt tttcggagga
      301 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002629             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:11754:15611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002629
VERSION     KCWK01002629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11754:15611"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68367.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          161 c          119 g          107 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gaccagtggc gtcaatgtgg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctgt
      241 actaccagtc agactcaagg aagcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggctgt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc ctatggcaca gcagcgcttc ttgcatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002630             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:17790:17426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002630
VERSION     KCWK01002630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17790:17426"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68368.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          143 c          140 g           93 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttggaagtga agttgtgaac tggtaccagc agaagccagc gcacgcccct gtgctggtca
      241 tctatgctaa tagcgaacgg ccctcaggga tccctgagcg attttctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg gggtgaggct gactattact
      361 gtcaggtgtg ggacatgcgt agtgatcaac cgctattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002631             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:13702:10941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002631
VERSION     KCWK01002631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13702:10941"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68369.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           88 a          160 c          123 g          110 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt agtaaaaaca tgtactggta ccagcagagg ccagggagcg ctcccaggtt
      241 attcctgtat tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caggtaacac agcgtttttg ctcatctctg gactccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtatgacagt agtgctgtgt tattcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01002632             272 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:10511:7686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002632
VERSION     KCWK01002632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 272)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 272)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..272
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10511:7686"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..234
                     /note="immunoglobulin light chain variable region"
     V_region        8..234
     V_segment       8..198
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <162..>206
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68370.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       202..234
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        235..>272
                     /gene="IGLC"
BASE COUNT           55 a           82 c           82 g           53 t
ORIGIN      
        1 acatggggca ctggtaccag cagaagccac cgcagggccc tgtattggtc atctttgctg
       61 acagtaaacg gccctcaggg atccctgagc gattctctgg ctccaactca gggaacaccg
      121 ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac tgtcaggtgt
      181 gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc ctaggtcagc
      241 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002633             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:24862:10718
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002633
VERSION     KCWK01002633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24862:10718"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68371.1"
                     /translation="DYYCAVWDNSLTSPLF"
     J_segment       413..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           94 a          157 c          120 g          110 t
ORIGIN      
        1 acatggggag cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag ccaccctcag cgtctgggac tcccgggcag agtgtcacca tctcttgctc
      181 tggaagcaac tccaacattg gaaataatta tgtatactgg taccagcacc tcccaggaac
      241 ggcccccaag ctcctcatct attatagtta tcagcgaccc tcaggggtcc ctgaccgatt
      301 ctctggctct aagtctggca cctcagcctc cctggccatc actggtctcc gaactgagga
      361 tgaggctgat tattactgtg cagtatggga taacagcctg accagtccgt tgttcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01002634             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:19017:12565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002634
VERSION     KCWK01002634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19017:12565"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68372.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          143 c          141 g           93 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttggaagtga agttgtgaac tggtaccagc agaagccagc gcaggcccct gtgctggtca
      241 tctatgctga tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg gggtgaggct gactattact
      361 gtcaggtgtg ggacatgcgt agtgatcaac cgctattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002635             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:23768:19544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002635
VERSION     KCWK01002635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23768:19544"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68373.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          105 a          138 c          122 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgcg cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002636             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:16111:3623
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002636
VERSION     KCWK01002636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16111:3623"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68374.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       389..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          120 g          106 t
ORIGIN      
        1 acatggggtg ggctcagaag cagaactctg ggtcctctcc accatggcct ggacccctcc
       61 cctgctcatc ctcctcactc tctgcacagg ttccgtggtt tcctctgagc tgactcagga
      121 gcctgcattg tctgtggcct tgggacatac agtcaggatg acctgccaag gagacagcct
      181 cagaacctat tatgcaagct ggtaccagca gaagccaggc caggtccctg tgctggtcat
      241 ctatggtaac aactaccggc cctcagggat cccaggccga ttctctgtct cctggtcagg
      301 aaacacaggt tccttgacca tcactgcggc tcaggtggaa gatgaggctg actattattg
      361 taagtcctgg gacagcagtg gtacccatta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002637             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:16803:6921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002637
VERSION     KCWK01002637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16803:6921"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68375.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       393..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>465
                     /gene="IGLC"
BASE COUNT           89 a          145 c          135 g           96 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gactctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaggtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtcctggtc
      241 atctatgcta ataacgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt ggggcgttac tagtgatcat cccttattcg gaggagggac ccggctgacc
      421 gtccaaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002638             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:12067:6864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002638
VERSION     KCWK01002638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12067:6864"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68376.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          157 c          116 g          114 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaagctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctgggca gtcggtcacc atctcctgca ctggacccag
      181 cagtgatatt gggtcttcta atgctgtgtc ttggtaccaa caacatccag gcaaagcccc
      241 ccaactcata atttttgagg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catttctggg ctccaggctg aggatgaggc
      361 tgattattac tgctgctcat atgtaggcag caacacttac atcttcgatg ttgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002639             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:27355:12025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002639
VERSION     KCWK01002639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:27355:12025"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68377.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           95 a          161 c          111 g          107 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcaactcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 gcctaccaca tacactggta ccagcagaag ccagggagtc ccccccggta tcttctgagt
      241 tacaaatcag actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaaaatgctt caacgaacac aggcatttta cacatctctg ggctccagtc tgaggatgag
      361 gctgactatt tctgtgccat tggacacagc agcggtcctt acatcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01002640             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:15844:11062
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002640
VERSION     KCWK01002640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:15844:11062"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68378.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           90 a          158 c          125 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 gggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcaac tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cggcatggga tgatagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01002641             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:14543:6283
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002641
VERSION     KCWK01002641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14543:6283"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..343
                     /note="immunoglobulin light chain variable region"
     V_region        13..343
     V_segment       13..308
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68379.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       310..343
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>381
                     /gene="IGLC"
BASE COUNT           73 a          117 c           98 g           93 t
ORIGIN      
        1 acatgggggg ttcaggctgc cccgactcag cctccctctg tgtccgggtc tcctggacag
       61 tcggtcacca tctcctgcac tggaaccagc agtgatattg ggtattataa cgctgtgtct
      121 tggtaccaac agcatccagg caaagccccc aaactcataa tttttgacgt cattaagcgg
      181 ccctcagggg tctctgatcg cttctctggc tccaagtctg gcgacacggc ctccctgacc
      241 atctctgggc tccgggctga ggatgaggct gattattact gcagctcata tgcaggcaga
      301 aataattttt tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      361 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002642             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:15987:4731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002642
VERSION     KCWK01002642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15987:4731"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68380.1"
                     /translation="DYYCQVWDISSDHVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          140 c          140 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctccgcgg cctcctttga cctgactcag
      121 ccacgctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aacttgtgaa ctggtaccaa cagaggccac cgcaggcccc tgtgctggtc
      241 atgtatgctg atagcgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaatacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacattag tagtgatcat gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002643             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:19292:13866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002643
VERSION     KCWK01002643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19292:13866"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68381.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          161 c          123 g          105 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcgtg atttatgagg tcaatcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct gacaacacgg cctccctgac catctctggc ctccagcctg aggacgaggc
      361 tgattattac tgcagctcat atgcaggcag cgacactttc gtgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002644             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:16621:3664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002644
VERSION     KCWK01002644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16621:3664"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68382.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           90 a          156 c          118 g          109 t
ORIGIN      
        1 acatggggtg ggatctcacg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc cggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002645             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:5028:9193
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002645
VERSION     KCWK01002645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5028:9193"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..440
                     /note="immunoglobulin light chain variable region"
     V_region        99..440
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68383.1"
                     /translation="DYYCQVYDNNDVLF"
     J_segment       407..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>482
                     /gene="IGLC"
BASE COUNT           92 a          158 c          123 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 cggaggacga ggccgattat tactgtcagg tatatgacaa taatgatgtg ttgttcggag
      421 gagggacccg gctgaccgtc gtaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002646             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:9165:8702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002646
VERSION     KCWK01002646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9165:8702"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68384.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       409..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          155 c          127 g          113 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca ccatctcctg
      181 cactgggagc gactccaaca ttggaggtta ttatgtgcag tggtaccagc agcttccagg
      241 aacggccccc aaactcctca tctatgaaaa tgataaacga ccctcagggg tttctgatcg
      301 attctctggc tcccagtctg attcctcagc ctccctgacc atcactggac tccagtctga
      361 ggatgaggct gattattact gccagtccta tgacagcagc ttgagtgttg tgttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01002647             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:6393:17430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002647
VERSION     KCWK01002647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:6393:17430"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..408
                     /note="immunoglobulin light chain variable region"
     V_region        78..408
     V_segment       78..371
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68385.1"
                     /translation="DYYCQSYDRSLSAVLF"
     J_segment       372..408
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           84 a          143 c          117 g          102 t
ORIGIN      
        1 acatggggac agtctccagc atggcctggt ctcctctcct cctcaccctt ctcattcact
       61 gcacagggtc ctgggcccag tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg
      121 ggcagagggc caccatctcc tgcactggga gcagctccaa cattggagat tattatgtgc
      181 agtggtacca gcagcttcca ggaacggccc ccagactcct catctatgaa aataataaac
      241 gacgctcagg ggcttctgat cgattctctg gctcccagtc tggtacctca gcctcgctga
      301 ccataagtgg actccagtct gaggatgagg ctgactatta ctgccagtct tatgacagaa
      361 gcttgagtgc tgtgttattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002648             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:8693:14932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002648
VERSION     KCWK01002648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:8693:14932"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68386.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          107 a          136 c          124 g           99 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg acctgacaca
      121 gccaccctca gtgtcagtgt ccccagggca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagaagtca ggccagggcc ctagactggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctggg cgattctcta gctccagttc
      301 agggacaaca gtcaccttga ccatcagcgg ggcccagaca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagaa gtcctaatca tgtgtttttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002649             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:14554:7032
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002649
VERSION     KCWK01002649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14554:7032"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68387.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          156 c          129 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtc cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaggca gctccaacat cggaagtcat agtgtatcct ggtaccagca ggtcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacggg cctcaggtgt ctctggccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002650             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:8669:19541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002650
VERSION     KCWK01002650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8669:19541"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68388.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          157 c          126 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 acctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattac tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002651             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:7232:18382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002651
VERSION     KCWK01002651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7232:18382"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68389.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          154 c          111 g          117 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttgctaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcatc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002652             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:13884:16084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002652
VERSION     KCWK01002652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13884:16084"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68390.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          163 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagcaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002653             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:12632:12796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002653
VERSION     KCWK01002653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12632:12796"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68391.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          160 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacga tagtgctgtg ttattcggag
      421 gagggacccg tctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002654             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:21059:7207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002654
VERSION     KCWK01002654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:21059:7207"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..389
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68392.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           86 a          156 c          120 g          109 t
ORIGIN      
        1 catggggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 actccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgatgttg ggtattatca tgctgtgtct tggtaccagc atcatccagg caaagccccc
      241 aaactcatga tttatgaggt caataaacgg cccgcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 gattattact gcagctcata tgcaggcagc aacgctttat tcttcggacg agggacccgc
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002655             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:11083:11863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002655
VERSION     KCWK01002655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11083:11863"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68393.1"
                     /translation="DYYCAIGHFSGNYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          157 c          115 g          112 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatct gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gataccaatc agagtcagat cacggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcact tcagcggtaa ttacatattc ggtgctggga
      421 cccgtctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002656             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:8543:10492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002656
VERSION     KCWK01002656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8543:10492"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..255
                     /note="immunoglobulin light chain variable region"
     V_region        8..255
     V_segment       8..215
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <183..>227
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68394.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       222..255
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        256..>293
                     /gene="IGLC"
BASE COUNT           65 a           87 c           76 g           65 t
ORIGIN      
        1 acatgggcat atactggtac caccagaagc cagggagtcc cccccggtat cttctgaggt
       61 acaaatcaga ctcagataag ggccagggct ctggagtccc cagccgcttc tctggatcca
      121 aagatgcttc agcgaacaca gggattttac acatctctgg actccagtct gaggatgagg
      181 ctgactatta ctgtgccatt ggacacagca gcggtgatta tatcttcggt ggtgggaccc
      241 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002657             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:25192:13606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002657
VERSION     KCWK01002657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:25192:13606"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    164..358
                     /note="immunoglobulin light chain variable region"
     V_region        164..358
     V_segment       164..319
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <286..>330
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68395.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       321..358
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        359..>396
                     /gene="IGLC"
BASE COUNT           73 a          125 c          107 g           91 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg tcaccaaact cctcatcttt
      181 gaaaataata agcgaccctc aggggtttct gaccgattct ctggctccaa gtctggttcc
      241 tcagcctccc tgaccatcac tggactccaa tctgaggatg aggctgatta ttattgttca
      301 tcatgggaaa gcagcctgaa ttgggtattc ggcggaggga cccggctgac cgtcctaggt
      361 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002658             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18237:4458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002658
VERSION     KCWK01002658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18237:4458"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..444
                     /note="immunoglobulin light chain variable region"
     V_region        111..444
     V_segment       111..402
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68396.1"
                     /translation="DYYCSAWDSSLTTRVF"
     J_segment       409..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          159 c          127 g          104 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctct ccttctcact ctgctggttc actgcacagg gtcctgggcc cagtctgtgc
      121 tgacgcagcc gccctcagca tctggggccc ccgggcagag ggtcaccatc tcctgcactg
      181 ggagcagctc caacatcggg gcgggttatt atgtatcctg gcaccagcag ttcccaggaa
      241 cagcccccaa actcctcatc tatgaaaata ataagcgacc ctcagggctt tctgaccgat
      301 tctcgggctc caagtctggt acctcagcct ccctgaccat cactcgactc caatctgagg
      361 atgaggctga ttattactgt tcagcatggg atagcagcct gactaccagg gttttcggcg
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002659             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:17805:2434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002659
VERSION     KCWK01002659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17805:2434"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68397.1"
                     /translation="DYYCAMWHSSVYGLF"
     J_segment       399..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           94 a          153 c          113 g          114 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttga gcagtggcat caatgttggt
      181 agttacagca tattctggta ccagcagaag ccagggagtc ctccccgatt ccttctgtac
      241 tactactcag actcaaataa tcaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatactt cagccaatgc agggctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccat gtggcacagt agtgtttatg gcttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002660             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:24511:10819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002660
VERSION     KCWK01002660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:24511:10819"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68398.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          154 c          122 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgcc ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002661             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:5610:10417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002661
VERSION     KCWK01002661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5610:10417"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..248
                     /note="immunoglobulin light chain variable region"
     V_region        8..248
     V_segment       8..212
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>220
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68399.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       216..248
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        249..>286
                     /gene="IGLC"
BASE COUNT           63 a           82 c           84 g           57 t
ORIGIN      
        1 acatggggga actaaaactg tgcactggta ccagcagaag ccaccgcagg gccctgtatt
       61 ggtcatcttt gctgatagta aacggccctc agggatccct gagcgattct ctggctccaa
      121 ctcagggaac accgccaccc tgaccatcag cagggtcgag gccggggatg aggctgacta
      181 ttactgtcag gtgtgggaca gtagtagtaa atggatattc ggcgggggga cccggctaac
      241 cgtcctaggt cagccaaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002662             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:16109:8159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002662
VERSION     KCWK01002662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16109:8159"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68400.1"
                     /translation="DYYCAAWDDRLTSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          157 c          123 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgataggc tgaccagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002663             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:5109:12212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002663
VERSION     KCWK01002663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5109:12212"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68401.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          156 c          126 g          114 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accctctcct
      181 gcactgggag cagctccaac tttggaaatt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag tctccctgac catcactgga ctccagtctg
      361 acgatgaggc tgattattac tgtcagtcct atgatagcag cctgagtgct gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002664             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:17526:9728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002664
VERSION     KCWK01002664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:17526:9728"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68402.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          150 c          137 g           92 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga ggtgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta agtatgtgca ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atctatgctg ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg ggtatgaggc tgactatttc
      361 tgtcaggtgt gggacgatag cagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002665             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:10806:8990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002665
VERSION     KCWK01002665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10806:8990"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68403.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       394..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          142 c          139 g           97 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactttac aggctctgcg gcctcctatg cggtgactca
      121 gccacgctca gtgtccgtgt ccccaggaca ggcggccagg atcacctgtg ggggagacaa
      181 cattggaagt aaaagtgtcc agtggtacca gcagacgcca ccgcaggccc ctgtactggt
      241 catttatggt gatagggaac ggccctcagg gatccctgaa cgattctctg gctccaactc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggatagta gtagtaaata tgtcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002666             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:9761:18515
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002666
VERSION     KCWK01002666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9761:18515"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68404.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          140 c          133 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgttcc caggacagac ggccagggtc acctgtggag gagacagcat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tgctggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgaacga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtattattc ggaggaggga cccgactgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002667             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:11097:6367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002667
VERSION     KCWK01002667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:11097:6367"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68405.1"
                     /translation="DYYCQSYDSSLSVALF"
     J_segment       416..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           91 a          157 c          128 g          112 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccctct
      181 cctgcactgg gagcagctcc aacattggag attattatgt gcagtggtac cagcagcttc
      241 caggaacggc ccccaaactc ctcatctatg aaaataataa gcgaccctca ggggtttctg
      301 atcgattctc tggctcccag tctggtacct cagcctccct gaccatcact ggactccagt
      361 ctgacgatga ggctgattat tactgtcagt cctatgatag cagcctgagt gttgcgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01002668             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:19819:18539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002668
VERSION     KCWK01002668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19819:18539"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68406.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       401..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           91 a          158 c          119 g          107 t
ORIGIN      
        1 acatggggtg gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccaa gcctatgctg actcagccgg cctccctctc
      121 agcatctcct ggagcatcag ccagtctcac atgcaccttc agcggtggca tcaatgttgc
      181 tgactaccac atacactggt accagcagaa gccagggagt cccccccggt atcttctgag
      241 atacagatca gactcagata agggccaggg ctctggagtc cccagccggt tctctggatc
      301 caaagatgct gcagcgaaca cagggatttt acgcatctct gggctccagt ctgaggatga
      361 ggctgactat tactgtgcca ttgggcacag cagcggtcct tacttcttcg gtgctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002669             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:13492:16466
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002669
VERSION     KCWK01002669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13492:16466"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..384
                     /note="immunoglobulin light chain variable region"
     V_region        82..384
     V_segment       82..341
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68407.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       347..384
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>422
                     /gene="IGLC"
BASE COUNT           89 a          135 c          101 g           97 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggcccccg ggcagagggt caccatctcc tgcactggga
      121 gcagctccaa catcggggcg ggttattatg tatcctggta ccagcagttc ccaggaacag
      181 cccccaaact cctcatctat gaaaataata aacgaccctc aggggtttct gaccgattct
      241 ctggctccaa gtctggtacc tcagcctccc tgaccatcac tggactccaa tctgaggatg
      301 aggctgatta ttactgctca gcatgggata gcagcctgag tatcaattac atcttcggtt
      361 ctgggacccg tctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      421 cg
//
LOCUS       KCWK01002670             403 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:13058:3493
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002670
VERSION     KCWK01002670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 403)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13058:3493"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    41..365
                     /note="immunoglobulin light chain variable region"
     V_region        41..365
     V_segment       41..327
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <290..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68408.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       329..365
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>403
                     /gene="IGLC"
BASE COUNT           82 a          128 c          111 g           82 t
ORIGIN      
        1 acatgggggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
       61 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      121 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      181 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      241 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      301 tcaggtgtgg gacacaacta ttgatcacgg cttcttcgga ggagggaccc ggctgaccgt
      361 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002671             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:10169:7754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002671
VERSION     KCWK01002671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10169:7754"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..425
                     /note="immunoglobulin light chain variable region"
     V_region        80..425
     V_segment       80..388
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68409.1"
                     /translation="DYYCAIGHSSGYIF"
     J_segment       389..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          157 c          113 g          105 t
ORIGIN      
        1 acatggggag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc tcctctctca
       61 ctgcacaggc tccctctcca agcctatgct gactcagccg gcctccctct cagcatctcc
      121 tggagcatca gccagtctca catgcacctt cagtggtggc atcaatgttg ctggctacca
      181 cacacactgg taccagcaga agccagggag tcctccccgg tatcttctga gatacaaatc
      241 agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat ccagagatgc
      301 ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg aggctgacta
      361 ttactgtgcc attgggcaca gcagcggtta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002672             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:19599:9538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002672
VERSION     KCWK01002672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19599:9538"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..266
                     /note="immunoglobulin light chain variable region"
     V_region        8..266
     V_segment       8..228
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68410.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       230..266
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           67 a           91 c           86 g           60 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaagtca aagtgtgcac tggtaccagc acaagccacc
       61 gcaggcccct gtactggtca tcttttatta taccgaacgg ccctcaggaa tccctgagcg
      121 attctctggc tccaaatcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggacacaact attgatcacg gcttattcgg
      241 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      301 cccg
//
LOCUS       KCWK01002673             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:10620:12984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002673
VERSION     KCWK01002673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10620:12984"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68411.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          141 c          138 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggagcac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002674             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:8482:9468
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002674
VERSION     KCWK01002674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:8482:9468"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68412.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          142 c          134 g           92 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag ggtctgcgac ctcctatgaa ctgactcagt
      121 caccctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa aactgtgcac tggtaccagc agaagccacc gcagggccct gtattggtca
      241 tctttgctga tagtaaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002675             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:15260:7250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002675
VERSION     KCWK01002675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:15260:7250"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68413.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          157 c          117 g          114 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcaag ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg gcagtcggtc accacctcct gcactggaac
      181 cagcagtgat attgggtctt ataatgctgt gtcttggtac caacaacatc caggcaaagc
      241 cccccaactc ataatttttg aggtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatttct gggctccagg ctgaggatga
      361 ggctgattat tactgctgct catatgtagg cagcaacact tacatcttcg atgttgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002676             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:10083:19664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002676
VERSION     KCWK01002676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10083:19664"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..389
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68414.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       392..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          140 c          136 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa tagtgtgcat tggtaccagc agaagccacc gcgggcccct gtattggtca
      241 tctctgttga tagcgaacgg ccctcaggga tccctgagcg attctctggt tccagatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggataatatt tataaatacg cggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002677             338 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:10636:5785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002677
VERSION     KCWK01002677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 338)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10636:5785"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..300
                     /note="immunoglobulin light chain variable region"
     V_region        10..300
     V_segment       10..264
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>272
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68415.1"
                     /translation="DYYCAIWHTGVYIF"
     J_segment       265..300
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        301..>338
                     /gene="IGLC"
BASE COUNT           68 a          103 c           84 g           83 t
ORIGIN      
        1 acatgggggg actcagctgc accttgagca gcggcatcaa tgttggtatt tacagcatat
       61 tctggtacca gcagaagcca gggagtcctc cccggtacct tctgtactac tactcagact
      121 caagtagaca ccacggctct ggagtcccca gccgcttctc tgggtccaaa gatgcttcag
      181 ccaatgcagg gcttttactg atctctgggc tccagtctga agatgaggct gattattact
      241 gtgccatatg gcacaccggc gtttacatct tcggttctgg gacccggctc accgtcctag
      301 gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01002678             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:13159:4214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002678
VERSION     KCWK01002678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13159:4214"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..230
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68416.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       232..269
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           63 a           90 c           79 g           75 t
ORIGIN      
        1 acatgggggg agcagctcca acattggagg ttattatgtg cagtggtacc agcagcttcc
       61 aggagcggcc cccaaactcc tcatctatga aaatgataaa cgaccctcag gggtttctga
      121 tcgattctct ggctcccagt ctgattcctc agcctccctg accatcactg gactccagtc
      181 tgaggatgag gctgattatt actgccagtc ctatgacagc agcttgagtg ttgtgttatt
      241 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01002679             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:21729:8601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002679
VERSION     KCWK01002679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21729:8601"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68417.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          156 c          126 g          110 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtctcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcaa gtcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc tcagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gaggggttac atcttcggtg
      421 ctgggacccg gctcgccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01002680             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13346:20634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002680
VERSION     KCWK01002680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13346:20634"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..381
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68418.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       393..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          147 c          133 g           98 t
ORIGIN      
        1 acatgggggg tctgggtctc aggaggcagc attgacggtg cctcagccat ggcctggacc
       61 cttctcctcc tcggcctcct cgctcactgc acaggctctg cgacctcctt tgagctgact
      121 cagccaccct cggtgtcagc ggcctcagga cagacggcca ggatcacctg tgggggagac
      181 aacattggaa ttaaatttgt ccactggtac cagcagaagc cagcgcaggc ccctgtgaag
      241 gtcatctatg ctgatgacaa acggccctca gggatccctg agagattctc tggctccaat
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tcctgtcagg tgtgggacag tgagactgat tattacatct tcggttctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01002681             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:19170:14295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002681
VERSION     KCWK01002681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19170:14295"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68419.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          100 a          137 c          124 g          105 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg aggtgacaca
      121 gtcaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagcaat
      181 tctggcaaat aattatgctc agtggttcca gcagaagcca gaccaggccc ctgtgttggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gttgacagca gtgcccatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002682             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:7172:4988
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002682
VERSION     KCWK01002682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7172:4988"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..443
                     /note="immunoglobulin light chain variable region"
     V_region        119..443
     V_segment       119..404
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68420.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       409..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT          108 a          141 c          128 g          104 t
ORIGIN      
        1 acatgggggg ggagcccagc tgtgctgtgg ttctaggagg aagagctctg ggtgtctcac
       61 catgacctgg accactgttc tgctcccctt tctcactctc tgcacaggct ctgaggcctc
      121 ctatgagctg acacagccac cctcagtgtc tgtgtcccca ggacagacgg ccaggatcac
      181 ctgctctgga gaaatactgg caaaaaaata tactcagtgg ttccaacagc agccaggcca
      241 ggcccctttc ctggtgatat ataaagacag tgagaggccc tcagggatcc ctgagcgatt
      301 ctctagctcc agttcaggga caacaattac cttgaccatc agtggggccc aggcagaaga
      361 tgaggctgac tattactgtc aatcagtaga cagcagtgga aatcttccgt tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01002683             390 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:14550:16480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002683
VERSION     KCWK01002683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 390)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 390)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..390
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14550:16480"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    22..352
                     /note="immunoglobulin light chain variable region"
     V_region        22..352
     V_segment       22..308
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <280..>324
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68421.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       322..352
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        353..>390
                     /gene="IGLC"
BASE COUNT           77 a          121 c          100 g           92 t
ORIGIN      
        1 acatgggcag gatcctgggc tcaggctgcc ccgactcaga ctccctctgt gtccgggtct
       61 cctggacagt cggtcaccat ctcctgcact ggaaccagca gtgatattgg gtattatcat
      121 gctgtgtctt ggtaccagca tcatccaggc aaagccccca aactcatgat ttatgaggtc
      181 aataaacggc ccgcaggggt ctctgatcgc ttctctggct ccaagtctgg caacacggcc
      241 tccctgacca tctctgggct ccagactgag gatgaggctg attattactg tagctcatat
      301 gcaggcagca acagtttatt cttcggagga gggacccggc tgaccgtcct aggtcagccc
      361 aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002684             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17894:10811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002684
VERSION     KCWK01002684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17894:10811"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..428
                     /note="immunoglobulin light chain variable region"
     V_region        107..428
     V_segment       107..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68422.1"
                     /translation="VYYCQVWDSSSEWVF"
     J_segment       392..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          146 c          136 g           94 t
ORIGIN      
        1 acatggggct gtctgggtct caggaggcag cattgacggt gcctcagcca tggcctggac
       61 ccttctcctc ctcggcctcc tcgcttactg cacaggctct gcgacctcct atgagctgac
      121 tcagccaccc tcagtgtcag cggcctcagg acagacggcc aggatcacct gtgggggaga
      181 caacattgga actaaaactg tgcactggta ccaacagaag gcagcacagg cccctatgct
      241 ggtcatcttt gctgatagca aacggccctc agggatccct gaccgattct ctggctccaa
      301 ctcagggaac accggcaccc tgaccatcag cggggtcgag gccggggatg aggctgtcta
      361 ttactgtcag gtgtgggaca gtagtagtga gtgggttttc ggcggaggga cccggctaac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002685             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:10551:5601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002685
VERSION     KCWK01002685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:10551:5601"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..433
                     /note="immunoglobulin light chain variable region"
     V_region        85..433
     V_segment       85..396
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68423.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       397..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           94 a          157 c          117 g          103 t
ORIGIN      
        1 acatggggag aggtagccgt gtccaccatg gccctgactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctcccagcct gtgctgacgc agccaccctc cctgtctgca
      121 tccccgggag caccggccag actcccctgc accctgagca gtgacctcag tgttggcagt
      181 aaaaacatgt actggtacca acagaagcca gggagcgctc ccaggttatt tctgtactac
      241 aactccgact cagacaagca gctgggacct ggggtcccca atcgagtctc tggctccaag
      301 gagacctcaa gtaacacagc gtttttgatc atctctgggc tccagcctga ggacgaggcc
      361 gattattact gtcaggtata tgacagtagt gctaatgtgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002686             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17296:12323
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002686
VERSION     KCWK01002686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17296:12323"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68424.1"
                     /translation="DYYCQVFDDSAVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          160 c          123 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gaagtaaaaa catatactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtcat acagcgtttt tgctcatttc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtttgacg atagtgctgt attattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002687             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:22318:14356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002687
VERSION     KCWK01002687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22318:14356"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..450
                     /note="immunoglobulin light chain variable region"
     V_region        117..450
     V_segment       117..413
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68425.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       416..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           89 a          160 c          132 g          107 t
ORIGIN      
        1 acatgggggg gctcattcct ggctgtggct caggaagcag agcctggagc gtctccacca
       61 tggcctgggc tccactcctc ctcaccctcc tcgctcactg cacagggtct tgggttgagg
      121 ttctgttcac gcagccccat tctgtgtcgg ggtctccggg gcagacggtc accatctcct
      181 gtacccgcag cagaggcaac attgacaata gttatgtgca gtggtaccag cagcgcccgg
      241 gcagtgcccc gaccacagtg atttacagag ataaccaaag agcctctggg gtccctgatc
      301 ggttctctgg ctccatcgac agctcctcca actctgcctc cctcaccatc tctgggctga
      361 agtctgagga cgaggctgac tactactgtc agtctactga tggcaactac aatcggttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01002688             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:17688:16275
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002688
VERSION     KCWK01002688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17688:16275"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68426.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          142 c          135 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccacga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaggccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tattgatcat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002689             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:9179:8910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002689
VERSION     KCWK01002689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:9179:8910"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68427.1"
                     /translation="DYYCGIGHSSGNYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          156 c          118 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat cctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa gtcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggaa ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt ggcattgggc acagcagcgg taattacata ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002690             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:19560:10927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002690
VERSION     KCWK01002690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:19560:10927"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..455
                     /note="immunoglobulin light chain variable region"
     V_region        110..455
     V_segment       110..418
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68428.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       419..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           93 a          166 c          123 g          111 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      181 gagcagtgac ctcagtgttg gaaataaaaa catatactgg taccagcaga agccagggag
      241 cgctcccagg ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt
      301 ccccaatcga gtctctggct ccaaggagac ctcaagtcat acagcgtttt tgctcatttc
      361 tgggctccag cctgaggacg aggccgatta ttactgtcag gtgtatgacg atagtgctgt
      421 gttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01002691             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:19421:4980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002691
VERSION     KCWK01002691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19421:4980"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..266
                     /note="immunoglobulin light chain variable region"
     V_region        8..266
     V_segment       8..229
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68429.1"
                     /translation="DYYCQVWDISTDHCVF"
     J_segment       233..266
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           64 a           85 c           93 g           62 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaagtga agttgtaaac tggtaccagc agaagccacc
       61 gcaggcccct gtgctggtca tctatgctga tagtgaccgg ccctcaggga tccctgagcg
      121 attctctggc tccaaatcag ggaacacggc caccctgacc atcagcgggg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggacattagt actgatcatt gtgtattcgg
      241 cggagggacc cggctaaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      301 cccg
//
LOCUS       KCWK01002692             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18931:6175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002692
VERSION     KCWK01002692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18931:6175"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68430.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          158 c          127 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002693             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:12947:6934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002693
VERSION     KCWK01002693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12947:6934"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68431.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           95 a          159 c          120 g          110 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aagagtgtca ccatctcctg
      181 ttctggaagc acctccaaca tcggaagcaa taatgtatcc tggtaccagc agctcccagg
      241 aacagctccc aaactcctct tttattataa tgatcaacga gcctcaggtg tctctgaccg
      301 attctcttgc tccaagtctg gcacgtcagc ctccctggcc atcagtgggc tccagaccga
      361 ggatgaggct gattattact gcgcatcatg ggatgatacc ctgagcggct acatcttcgg
      421 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01002694             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:13267:9849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002694
VERSION     KCWK01002694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13267:9849"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68432.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          157 c          126 g          111 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtctcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc tcagtctggc acgtcagcct ccctggccat cagtgggctc caggccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagtct gagcggttac atcttcggtg
      421 ctgggacccg gctcgccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01002695             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:19080:14319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002695
VERSION     KCWK01002695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19080:14319"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68433.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          158 c          120 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002696             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:16712:5268
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002696
VERSION     KCWK01002696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16712:5268"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68434.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          156 c          120 g          109 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcaa cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcaac tccaacatcg gaagttataa tgtgtcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attataatga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agcggttaca tcttcgctgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01002697             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:7849:9348
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002697
VERSION     KCWK01002697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7849:9348"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68435.1"
                     /translation="DYYCSSYGGRNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          153 c          122 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg ctcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagtt catatggagg cagaaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002698             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:18139:4750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002698
VERSION     KCWK01002698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18139:4750"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..399
                     /note="immunoglobulin light chain variable region"
     V_region        97..399
     V_segment       97..362
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <324..>371
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68436.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       363..399
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        400..>437
                     /gene="IGLC"
BASE COUNT           94 a          138 c          110 g           95 t
ORIGIN      
        1 acatgggatc aacgcagagt acatggggtc agaagcagaa ctctgggtcc tctccaccat
       61 ggcctggacc cctcccctgc tcatcctcct cactctctgc attgtctgtg gccttgggac
      121 aaacagtcag gatgacctgc caaggagaca gcctcaaaac ctattatgca agctggtacc
      181 agcagaagcc aggccaggtc cctgtgctgg tcatctatgg taacaactac cggccctcag
      241 ggatcccagg ccgattctct gtctcctggt caggaaacac aggttccttg accatcactg
      301 cggctcaggt ggaagatgag gctgactatt actgtaagtc ctgggacagc agtggtaccc
      361 attacatctt cggtgctggg acccggctca ccgtcctagg tcagcccaag gcttccccca
      421 cggtcactct gttcccg
//
LOCUS       KCWK01002699             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:8441:10846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002699
VERSION     KCWK01002699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8441:10846"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68437.1"
                     /translation="DYYCAIWHSSAYIF"
     J_segment       403..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           97 a          160 c          109 g          110 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcaggcagac tcagctgcac cttgagcagt gacatcaatg
      181 ttggtactta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacaa ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcaggac ttttactgat ctctggtctc cggtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttacatcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002700             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:10439:9720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002700
VERSION     KCWK01002700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:10439:9720"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..456
                     /note="immunoglobulin light chain variable region"
     V_region        126..456
     V_segment       126..417
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68438.1"
                     /translation="DYYCQSYDSSLIVVLF"
     J_segment       419..456
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           96 a          157 c          123 g          118 t
ORIGIN      
        1 acatggggaa agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca cttcacagtt ccagggtcct
      121 gggcccagtc tgtgctgacg cagccgccct caatctctgg ggcgcccggg cagagggtca
      181 ccatctcctg cactgggagc agctccaaca ttggagatta ttttgtgcag tggtaccagc
      241 accttccagg aacggccccc aaacttctca tctatgaaaa taataagcga ccctcaggga
      301 tttctgatcg attctctggc tcccagtctg gaacctcagc ctccctgacc atcactggac
      361 tccagtctga ggatgaggct gattattact gccagtccta tgacagcagt ttgattgttg
      421 tgttattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      481 tcactctctt cccg
//
LOCUS       KCWK01002701             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:7527:13133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002701
VERSION     KCWK01002701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7527:13133"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68439.1"
                     /translation="VYYCQVWDSSSEWVF"
     J_segment       391..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          145 c          137 g           93 t
ORIGIN      
        1 acatgggggg tctgggtctc aggaggcagc attgacggtg cctcagccat ggcctggacc
       61 cttctcctcc tcggcctcct cgcttactgc acaggctctg cgacctccta tgagctgact
      121 cagccaccct cagtgtcagc ggcctcagga cagacggcca ggatcacctg tgggggagac
      181 aacattggaa ctaaaactgt gcactggtac caacagaagg cagcacaggc ccctatgctg
      241 gtcatctttg ctgatagcaa acggccctca gggatccctg accgattctc tggctccaac
      301 tcagggaaca ccggcaccct gaccatcagc ggggtcgagg ccggggatga ggctgtctat
      361 tactgtcagg tgtgggacag tagtagtgag tgggttttcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002702             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11503:11490
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002702
VERSION     KCWK01002702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11503:11490"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68440.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          162 c          120 g          110 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggta gtaaaaacat gtactggtac caacagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcaggtg tatgacagta gtgctaatgt cttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002703             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:11678:9763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002703
VERSION     KCWK01002703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11678:9763"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68441.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           92 a          140 c          134 g          102 t
ORIGIN      
        1 acatgggggt gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaggccac cgcaggcccc tatactggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagtgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacatata tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002704             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:7254:7066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002704
VERSION     KCWK01002704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:7254:7066"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68442.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          163 c          120 g          111 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag tagtgacctc
      181 agtgttggta gtaaaaacat ctactggtac cagctgaagc cagggagcgc tcccaggtca
      241 ttcctgtact actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcaggtc tatgacagta gtgctaatgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002705             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:8397:10053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002705
VERSION     KCWK01002705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:8397:10053"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68443.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          146 c          129 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtacact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttgttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg tcccctcggt cactctcttc ccg
//
LOCUS       KCWK01002706             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:15727:14520
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002706
VERSION     KCWK01002706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15727:14520"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68444.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          161 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtttgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002707             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:6640:9799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002707
VERSION     KCWK01002707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6640:9799"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68445.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           89 a          156 c          121 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacgtacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg ggtccccagc cgcttctctg
      301 gatccagtaa tggttcagtg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tctttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002708             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:19606:17596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002708
VERSION     KCWK01002708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19606:17596"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..436
                     /note="immunoglobulin light chain variable region"
     V_region        91..436
     V_segment       91..399
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68446.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       400..436
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           90 a          162 c          116 g          106 t
ORIGIN      
        1 acatgggggg cctcagaggt agccgtgtcc accatggccc tgactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc accctccctg
      121 tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagcagtga cctcagtgtt
      181 ggtaataaaa acatgtactg gtaccaacag aagccaggga gcgctcccag gttattcctg
      241 tactactatt ccgactcaga caagcagctg ggacctgggg tcccccatcg agtctctggc
      301 tccaaggaga cctcaactaa cacagcgttt ttgctcatct ctgggctcca gcctgaggac
      361 gaggccgatt actactgtca ggtgtatgac agtagtgctg tgttattcgg aggagggacc
      421 cgactgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002709             274 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:13110:3265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002709
VERSION     KCWK01002709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 274)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 274)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13110:3265"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..236
                     /note="immunoglobulin light chain variable region"
     V_region        8..236
     V_segment       8..200
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <164..>208
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68447.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       204..236
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        237..>274
                     /gene="IGLC"
BASE COUNT           56 a           81 c           82 g           55 t
ORIGIN      
        1 acatggggtg cactggtacc agcagaagcc accgcagggc cctgtattgg tcatctttgc
       61 tgatagtaaa cggccctcag ggatccctga gcgattctct ggctccaact cagggaacac
      121 cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt actgtcaggt
      181 gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg tcctaggtca
      241 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002710             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:7146:4290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002710
VERSION     KCWK01002710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7146:4290"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..430
                     /note="immunoglobulin light chain variable region"
     V_region        85..430
     V_segment       85..391
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68448.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       393..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           87 a          159 c          115 g          107 t
ORIGIN      
        1 acatggggag aggtagccgt gtccaccatg gccctgactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctcccagcct gtgctgactc agccaccctc cctgtctgca
      121 tccccgggag catcggccag actcccctgc accctgagca gtgacctcag tgttggtagt
      181 aaaaacatgt actggtacca gcagaagcca gggagcgctc ccaggttatt cctgtactac
      241 tactccgact cagacaagca gctgggacct ggggtcccca atcgagtctc tggctccaag
      301 gagacctcaa gtaacacagc gtttttgctc atctctgggc tccagcctga ggacgaggcc
      361 gattatttct gccagctatt tgacagtagt gttgtgttct tcggaggagg gacccgactg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002711             336 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:13645:12491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002711
VERSION     KCWK01002711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 336)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13645:12491"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..298
                     /note="immunoglobulin light chain variable region"
     V_region        8..298
     V_segment       8..261
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <226..>270
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68449.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       262..298
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        299..>336
                     /gene="IGLC"
BASE COUNT           71 a          104 c           85 g           76 t
ORIGIN      
        1 acatgggctg gacagtcggt caccatctcc tacactggaa ccagcagtga cattggtggt
       61 tataaccgtg tctcctggta ccaacagcac ccaggcaaag accccaaatt catgatttat
      121 gaggtcagtc aacggccctc aggggtctct gatcgtatct ctggctccaa gtctggcaac
      181 acggcctccc tgaccatctc tgggctccag actgaggatg aggctggtta ttactgcagc
      241 tcatttgcag gtaccaacac tggcttaatc ggtggaggga cccggctgac cgtcctaggt
      301 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002712             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11061:10213
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002712
VERSION     KCWK01002712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11061:10213"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68450.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           92 a          160 c          124 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg acgcagccac
      121 cctccctgtc tgcatccccg ggagcaccgg ccagactccc ctgcaccctg agcagtgact
      181 tcagtgttgg tggtaaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tatttctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tatatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002713             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:22964:16226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002713
VERSION     KCWK01002713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22964:16226"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68451.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           87 a          142 c          135 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctttgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaggccaccg caggcccctg tgctggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgaccga ttctctggct ccaagtcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002714             299 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:23015:10716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002714
VERSION     KCWK01002714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 299)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:23015:10716"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..261
                     /note="immunoglobulin light chain variable region"
     V_region        6..261
     V_segment       6..225
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>233
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68452.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       226..261
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        262..>299
                     /gene="IGLC"
BASE COUNT           72 a           84 c           85 g           58 t
ORIGIN      
        1 acatgggcgg agacaacatt ggaattaaaa atgtccactg gtaccagcag aagccagcac
       61 aggcccctgt ggtagtcatc tatgctgata acaaacggcc ctcagggatc cctgagcgac
      121 tctctggctc caactcaggg aatattgcca ccctgaccat cagcagggtc gaggccgggg
      181 atgaggcaga ctattactgt caggtgtggg acagtagtag taaatgggta ttcggcggag
      241 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002715             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:15319:5980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002715
VERSION     KCWK01002715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15319:5980"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68453.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          140 c          133 g           95 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgaa ttgactcagt
      121 cattctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa aactgtgcac tggtaccaac agaagccacc gcagggccct gtattggtca
      241 tctttgctga tagtagacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002716             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:11268:19195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002716
VERSION     KCWK01002716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:11268:19195"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..395
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68454.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       396..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           93 a          153 c          120 g          104 t
ORIGIN      
        1 acatgggggg ggtacagaag gcaggactca ggacaatctc cagcatggcc tggttccctc
       61 tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg ctgactcagc
      121 ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct ggaagcagct
      181 ccaacatcgg aagtaataat gtgtcctggt accagcacct cccaggaaca gctcccaaac
      241 tcctcatcta ttataatgat caacgaggct caggtgtctc tgaccgattc tctggctcca
      301 agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat gaggctgatt
      361 attactgcgc agcgtgggat gatagcctga gcagttacat cttcgctgct gggacccggc
      421 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002717             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:13647:13534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002717
VERSION     KCWK01002717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13647:13534"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68455.1"
                     /translation="EYYCLLYCSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          150 c          117 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtactg tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002718             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:23899:15964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002718
VERSION     KCWK01002718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23899:15964"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68456.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          143 c          134 g           94 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca cagggtctgc gacctcctat gaactgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc agcagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgatagtaaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002719             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:27491:17815
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002719
VERSION     KCWK01002719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:27491:17815"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68457.1"
                     /translation="DYYCQVWDSTSDHVFF"
     J_segment       387..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           87 a          141 c          135 g           98 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccgc
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacgacattg
      181 gaagtaaata tgtgcactgg taccagcaga agccaccgca ggcccctgtg ctggtcatct
      241 attatgatgg cgaacggccc tcagggatcc ctgagcgatt ctctgactcc aaatcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cagtactagt gatcatgtgt ttttcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002720             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10270:10951
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002720
VERSION     KCWK01002720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10270:10951"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68458.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          158 c          112 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tggactccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcctaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002721             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:18023:15546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002721
VERSION     KCWK01002721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18023:15546"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68459.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       398..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          153 c          122 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctaca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagaccc
      241 caaattcatg atttatgagg tcagtcaacg gccctcaggg gtctctgatc gtatctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tggttattac tgcagctcat ttgcaggtac caacactggc ttaatcggtg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgt cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002722             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:23204:6788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002722
VERSION     KCWK01002722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23204:6788"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68460.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          161 c          123 g          110 t
ORIGIN      
        1 atgggggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggta gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcaggtg tatgacagta gtgctaatgt cttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002723             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:22661:9370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002723
VERSION     KCWK01002723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:22661:9370"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68461.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       413..448
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           92 a          162 c          125 g          107 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctcgt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cacagccgcc ctcagtgtct ggggccccag ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggaggt tattatatat cctggtacca gcagctccca
      241 ggaacggccc ccaaactcct cgtctatgac aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggttcctca gccaccctga ccatcactgg gctccagact
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtctgagtgc tcgggtattc
      421 ggcggaggga cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01002724             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:18485:11144
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002724
VERSION     KCWK01002724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18485:11144"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..394
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68462.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           87 a          156 c          118 g          115 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcaa gctgccccga
      121 ctcagcctcc ctctgtgtcc gggtctcctg ggcagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tattgggtct tataatgctg tgtcttggta ccaacaacat ccaggcaaag
      241 ccccccaact cataattttt gaggtcaata agcggccctc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatttc tgggctccag gctgaggatg
      361 aggctgatta ttactgctgc tcatatgtag gcagcaacac ttacatcttc gatgttggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002725             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:8169:2756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002725
VERSION     KCWK01002725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8169:2756"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..442
                     /note="immunoglobulin light chain variable region"
     V_region        113..442
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68463.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       413..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>481
                     /gene="IGLC"
BASE COUNT           94 a          160 c          120 g          107 t
ORIGIN      
        1 acatggggag cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag ccaccctcag cgtctggggc tcccgggcag agtgtcacca tctcgtgctc
      181 tggaagcagc tccaacattg gaactaatta tgtatactgg taccaacacc tcccaggaac
      241 ggcccccaaa ctcctcatct attatagtaa tcagcgaccc tcaggggtcc ctgaccgatt
      301 ctctggctct aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga
      361 tgaggctgat tattactgtg cagcatggga taacagcctg accagtccgg tcttcggagg
      421 agggacccgg ctgaccgtcc taagtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01002726             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:11865:17709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002726
VERSION     KCWK01002726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11865:17709"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..287
                     /note="immunoglobulin light chain variable region"
     V_region        8..287
     V_segment       8..250
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <212..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68464.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       255..287
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>325
                     /gene="IGLC"
BASE COUNT           66 a          103 c           82 g           74 t
ORIGIN      
        1 acatggggtc accatctcct gctctggaag cagctccaat attggaagta attctgtata
       61 ctggtaccag cagttcccag gaacggcccc caaactcctc atctattata gtaatcagcg
      121 accctcaggg gtccctgacc gagtctctgg ctctaagtcg ggcacctcag cctccctggc
      181 catcactggt ctccgatctg aggatgaggc tgattattac tgtgcagcat gggatgacag
      241 cctgagaagt ccgctattcg gcggagggac ccggctgacc gtcctaggtc agcccaaggc
      301 tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002727             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:21545:2923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002727
VERSION     KCWK01002727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21545:2923"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68465.1"
                     /translation="VYYCQVWDSSSEWVF"
     J_segment       386..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          144 c          135 g           91 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgagc tgactcagcc
      121 accctcagtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa actgtgcact ggtaccaaca gaaggcagca caggccccta tgctggtcat
      241 ctttgctgat agcaaacggc cctcagggat ccctgaccga ttctctggct ccaactcagg
      301 gaacaccggc accctgacca tcagcggggt cgaggccggg gatgaggctg tctattactg
      361 tcaggtgtgg gacagtagta gtgagtgggt tttcggcgga gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002728             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:19462:16794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002728
VERSION     KCWK01002728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19462:16794"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68466.1"
                     /translation="AYYCQVWDSDTDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          153 c          128 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gcctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 atcggaacta gttttgtgca ctggtaccag cagaagccag cgcaggcccc tatacaggtc
      241 atctatgctg ataccaaacg gccctcaggg atccctgaga gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctattac
      361 tgtcaggtgt gggacagtga tactgatcat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002729             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:21052:11600
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002729
VERSION     KCWK01002729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21052:11600"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68467.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          161 c          124 g          105 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcgtg atttatgagg tcaatcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct gacaacacgg cctccctgac catctctggc ctccagcctg aggacgaggc
      361 tgattattac tgcagctcgt atgcaggcag cgacactttc gtgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002730             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:12160:16062
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002730
VERSION     KCWK01002730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12160:16062"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68468.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          147 c          131 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctccgatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa gagtgtgcac tggtaccagc acaagccacc gcaggcccct atcctggtca
      241 tctattatta taccgaacga ccctcggcga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacactact attgatcatg gctttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002731             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:16088:13254
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002731
VERSION     KCWK01002731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16088:13254"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68469.1"
                     /translation="DYYCQVWDSTSDHYIF"
     J_segment       392..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          153 c          131 g           95 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag ggtcacctgt gggggagaca
      181 acattggaac tacgtttgtc cactggtacc agcagaatcc accgcaggcc cctgtgcagg
      241 tcatctttgc ggataacaaa cggccctcag ggatccctga acgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt actagtgatc attacatctt cggtggtggg acccgcctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01002732             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:6324:13452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002732
VERSION     KCWK01002732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:6324:13452"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..446
                     /note="immunoglobulin light chain variable region"
     V_region        113..446
     V_segment       113..409
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68470.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       410..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           84 a          167 c          129 g          104 t
ORIGIN      
        1 acatgggggc agtgtggctg cctcagcaga gccctgagga gtctgcacca tggcctggac
       61 cccaatcctc ctcctcctca ctctcctcct tcactgcaca gggtctctct cccagcctgt
      121 gctgactcag tcgccctctg cctctgcctc cctgggagcc tcggtcaagc tcacctgcac
      181 tctgagcagt ggccactaca gctacaccat cgcatggcat cagcagcagc aagggaaggc
      241 ccctcggttc ttgatgtggc ttaagagtga tggcagccac accaaggggg acggggtccc
      301 tgatcgcttc tcaggctcca gctccggggc tgagcgctac ctcaccatct ccaacctcca
      361 gtctgaggat gaggctgatt attactgtca gacctgggat attggcattt gggtattcgg
      421 cggagggacc cggctaaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01002733             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:9462:17612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002733
VERSION     KCWK01002733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9462:17612"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..449
                     /note="immunoglobulin light chain variable region"
     V_region        120..449
     V_segment       120..413
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68471.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       418..449
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>488
                     /gene="IGLC"
BASE COUNT           97 a          161 c          121 g          109 t
ORIGIN      
        1 acatggggga gcttcagctg cgggtacaga aggcaggact caggataatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agttccaggg tcctgggccc
      121 agtctgtgct gactcagcca ccctcagcgt ctgggactcc cgggcagagt gtcaccatct
      181 cgtgctctgg aagcagctcc aacattggaa ctaattatgt atactggtac caacacctcc
      241 caggaacggc ccccaaactc ctcatctatt atagtaatca gcgaccctca ggggtccctg
      301 accgattctc tggctctaag tctggcacct cagcctccct ggccatcact ggtctccgat
      361 ctgaggatga ggctgattat tactgtgcag catgggataa cagcctgacc agtccggtat
      421 tcggaggagg gacccggctg accgtcctaa gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01002734             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:20026:16007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002734
VERSION     KCWK01002734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20026:16007"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68472.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          154 c          126 g          112 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac catctcctgc
      181 actgggagca gctccaacat tggaggttat tatgtgcagt ggtaccagca gcttccagga
      241 acggccccca aactcctcat ctatgaaaat gataaacgac cctcaggggt ttctgatcga
      301 ttctctggct cccagtctga tacctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagcagct taagtgttgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002735             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:10529:7813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002735
VERSION     KCWK01002735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10529:7813"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..226
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68473.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       228..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           63 a           95 c           74 g           69 t
ORIGIN      
        1 acatgggagc tccaacattg gaggttatta tatatcctgg taccagcagc tcccaggaac
       61 ggcccccaaa ctcctcgtct atgacaataa taagcgaccc tcaggggttt ctgaccgatt
      121 ctctggctcc aagtctggtt cctcagccac cctgaccatc actgggctcc agactgagga
      181 tgaggctgat tattactgcc agtcctatga cagcagtctg agtgctcggg tattcggcgg
      241 agggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01002736             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22679:10640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002736
VERSION     KCWK01002736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22679:10640"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68474.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          130 g           95 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca gcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002737             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:14414:19926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002737
VERSION     KCWK01002737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14414:19926"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68475.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          155 c          126 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agactccctc agcgtctgag gtcgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagaaat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagcgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002738             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:14678:13218
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002738
VERSION     KCWK01002738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14678:13218"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68476.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           91 a          154 c          119 g          109 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat cgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat aatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaagacg gcctccctga ccatctctgg actccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacgcttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002739             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:24018:4137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002739
VERSION     KCWK01002739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:24018:4137"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68477.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          142 c          133 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tgctggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgaccga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002740             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:14220:16748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002740
VERSION     KCWK01002740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14220:16748"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68478.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           81 a          165 c          115 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac gttggtggtt ctaactctgt ctcctggtac caacaacacc caggcagagc
      241 ccccaaactc atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct ggcctccagt ctgaggacga
      361 ggctgattat tactgttgtt cacattcaac cagtagcact tacgtcttcg gtcctgggac
      421 ccggctcacc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002741             354 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:25282:16955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002741
VERSION     KCWK01002741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 354)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25282:16955"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..316
                     /note="immunoglobulin light chain variable region"
     V_region        8..316
     V_segment       8..273
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <241..>288
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68479.1"
                     /translation="DYYCQVWGSRSDHPVF"
     J_segment       282..316
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        317..>354
                     /gene="IGLC"
BASE COUNT           70 a          107 c          108 g           69 t
ORIGIN      
        1 acatgggagc caccctcggt gtcagcggcc tcaggacaga cggccagggt cacctgtggg
       61 gcaggtaaca ttggaagtaa ttttgttcac tggtaccagc agaagccacc gcaggcccct
      121 gttcaggtca tctatgcaga taacagacgg ccctcaggga tccctgagcg attctctggc
      181 tccaattcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct
      241 gactattact gtcaggtgtg gggcagtcgt agtgatcatc cggtattcgg cggagggacc
      301 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002742             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:17129:13942
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002742
VERSION     KCWK01002742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17129:13942"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..350
                     /note="immunoglobulin light chain variable region"
     V_region        20..350
     V_segment       20..313
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <278..>322
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68480.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       314..350
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        351..>388
                     /gene="IGLC"
BASE COUNT           77 a          123 c           99 g           89 t
ORIGIN      
        1 acatggggga tcctgggctc aggctgccct gactcagcct ccctcaatgt ctgggtctcc
       61 tggacagtcg gtcaccatct cctacactgg aaccagcagt gacattggtg gttataaccg
      121 tgtctcctgg taccaacagc acccaggcaa agaccccaaa ttcatgattt atgaggtcag
      181 tcaacggccc tcaggggtct ctgatcgtat ctctggctcc aagtctggca acacggcctc
      241 cctgaccatc tctgggctcc agactgagga tgaggctggt tattactgca gctcatttgc
      301 aggtaccaac actggcttaa tcggtggagg gacccggctg accgtcctag gtcagcccaa
      361 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002743             278 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:22122:19070
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002743
VERSION     KCWK01002743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 278)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:22122:19070"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..238
                     /note="immunoglobulin light chain variable region"
     V_region        8..238
     V_segment       8..203
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <168..>212
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68481.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       204..238
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        239..>278
                     /gene="IGLC"
BASE COUNT           53 a           92 c           67 g           66 t
ORIGIN      
        1 acatggggca gaagccaggg agtcctcccc ggtaccttct ctactactac tcagactcaa
       61 gtaaacacca gggctctgga gtccccagcc gcttctctgg atccaaagat gcttcggcca
      121 atgcaggcct tttactgatc tctgggctcc agtctgaaga tgaggctgac tattactgtg
      181 ccatatggca cagcagcgct tcttacttct tcggttccgg gacccggctc accgtcctgg
      241 gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01002744             514 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:3028:8792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002744
VERSION     KCWK01002744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 514)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:3028:8792"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    295..476
                     /note="immunoglobulin light chain variable region"
     V_region        295..476
     V_segment       295..436
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <404..>448
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68482.1"
                     /translation="VYYCQVWDSSSEWVF"
     J_segment       440..476
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        477..>514
                     /gene="IGLC"
BASE COUNT          112 a          124 c          161 g          117 t
ORIGIN      
        1 acatgggggc tttttctttc ggcggagcgc ggcggcaaga tggccgtgca aatttccaag
       61 aagaggaagt ttgtcgctga tggcatcttc aaagctgaac tgaatgagtt tcttactcgg
      121 gagctggctg aagatggcta ctctggagtt gaggtgcgag ttacaccaac caggacagaa
      181 atcattatct tagccaccag aacacagaat gttcttggtg agaagggccg gcggattcgg
      241 gaactgactg ctgtagttca gaagaggttt ggctttccag agggcagtgt agagctttgc
      301 tgatagcaaa cggccctcag ggatccctga ccgattctct ggctccaact cagggaacac
      361 cggcaccctg accatcagcg gggtcgaggc cggggatgag gctgtctatt actgtcaggt
      421 gtgggacagt agtagtgagt gggttttcgg cggagggacc cggctaaccg tcctaggtca
      481 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002745             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:11601:11501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002745
VERSION     KCWK01002745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11601:11501"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68483.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           81 a          160 c          127 g          107 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt ctgatggcgt ctcctggtac cagcagcact cagggacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 cgctgattat tactgttgct catataggag tggaaacact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002746             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:13519:15283
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002746
VERSION     KCWK01002746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13519:15283"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68484.1"
                     /translation="DYYCASYEGSNTFLF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          158 c          121 g          105 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca gtggaaccag
      181 cagtaagatt gggtatcaca atgctgtgtc ctggtaccaa gagcatccag gcaaagcccc
      241 caaactcatg atttatgacg tcaataagcg gccctcaggg atctctgatc gcttctctgg
      301 ctccaagtct ggcgacacgg cctccctgac catctctggg ctccagcctg atgatgaggg
      361 tgattattac tgcgcctcat atgaaggcag caacactttc ctcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002747             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:10421:12047
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002747
VERSION     KCWK01002747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10421:12047"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68485.1"
                     /translation="HYYCQVWDISSEHVLF"
     J_segment       392..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          142 c          135 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagc ctctgcggcc tcctatgaac tgactcagcc
      121 accctcggtg tcagtgtccc ccggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgat gttgtgaatt ggtaccacca gaagccaccg caggcccctg tactggtcat
      241 ctatgctgat agcgatcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctc actattactg
      361 tcaggtgtgg gacattagta gtgagcatgt attattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002748             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:12814:5424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002748
VERSION     KCWK01002748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12814:5424"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..455
                     /note="immunoglobulin light chain variable region"
     V_region        110..455
     V_segment       110..416
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68486.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       418..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           89 a          168 c          124 g          112 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      181 gagcagtgac ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag
      241 cgctcccagg ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt
      301 ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc
      361 tgggctccag cctgaggacg aggccgatta tttctgccag gtgtttgaca gtagtgttgt
      421 gttcttcgga ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01002749             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15445:3097
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002749
VERSION     KCWK01002749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15445:3097"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68487.1"
                     /translation="DYYCAAWDNSLSSYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           97 a          156 c          120 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaataa tgtgtcctgg taccagcacc tcccaggaac
      241 agctcccaaa ctcctcatct attataatga tcaacgagac tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcgtggga taatagcctg agcagttaca tcttcgctgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01002750             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:15031:13902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002750
VERSION     KCWK01002750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15031:13902"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68488.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          161 c          111 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaagga tgcttcggcc aatgcaggcc ttttagtgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc tttggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002751             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:28056:13238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002751
VERSION     KCWK01002751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:28056:13238"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68489.1"
                     /translation="DYYCQSADSSGNHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          134 c          124 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctcttcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc agtggttcca gcagaagcca ggccaggccc ctgtgttggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgaa cgattctcta gttccagtac
      301 agggacaaca cttaccttga ccatcagtgg ggcccaggtg gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagca gtggtaatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002752             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:21549:9984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002752
VERSION     KCWK01002752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:21549:9984"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68490.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          152 c          120 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctga
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002753             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:22953:16826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002753
VERSION     KCWK01002753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22953:16826"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68491.1"
                     /translation="DYYCGLGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          157 c          117 g          107 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cacgggtggc atcaatgttg
      181 ctgactacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacacatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtggc cttgggcaca gcagcggtga ttacatcttc gctgatggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002754             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:19339:6181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002754
VERSION     KCWK01002754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:19339:6181"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..248
                     /note="immunoglobulin light chain variable region"
     V_region        8..248
     V_segment       8..212
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>220
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68492.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       216..248
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        249..>286
                     /gene="IGLC"
BASE COUNT           63 a           82 c           84 g           57 t
ORIGIN      
        1 acatggggga attaaaactg tacactggta ccagcagaag ccaccgcagg gccctgtatt
       61 ggtcatcttt gctgatagta agcggcccac agggatccct gagcgattct ctggctccaa
      121 ctcagggaac accgccaccc tgaccatcag cagggtcgag gccggggatg aggctgacta
      181 ttactgtcag gtgtgggaca gtagtagtaa atggatattc ggcgggggga cccggctaac
      241 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002755             363 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:22148:13967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002755
VERSION     KCWK01002755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 363)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22148:13967"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..325
                     /note="immunoglobulin light chain variable region"
     V_region        8..325
     V_segment       8..285
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <253..>297
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68493.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       292..325
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        326..>363
                     /gene="IGLC"
BASE COUNT           79 a          109 c           94 g           81 t
ORIGIN      
        1 acatgggcag catctcctgg agcatcagcc agtctcacat gcaccttcag cggtggcatc
       61 aatgttgctg gctaccacat atactggtac cagcagaagc cagggagtcc cccccggtat
      121 cttctgaggt acaaatcaga ctcagataag ggccaggggt ctggagtccc cagccgcttc
      181 tctggatcca aagatgcttc agcgaacaca gggattttac gcatctctgg actccagtct
      241 gaggatgagg ctgactatta ctgtgccatc ggacacagca gcggtgatta tatcttcggt
      301 gctgggaccc ggctcatcgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      361 ccg
//
LOCUS       KCWK01002756             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:25172:11929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002756
VERSION     KCWK01002756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25172:11929"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68494.1"
                     /translation="DYYCQSADSSSHHYIF"
     J_segment       395..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          105 a          134 c          120 g          107 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg aactgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 gctggaaaaa aaatatactc agtggttcca gcggaagcca ggccaggccc ctgttttggt
      241 gatctataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gttccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ttgtcaatca gcagacagta gtagtcatca ttatatcttc ggtcctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002757             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:23170:12284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002757
VERSION     KCWK01002757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23170:12284"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68495.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           94 a          134 c          118 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tacattgcca aaaaaatatg
      181 cttattggtt ccagcggaag ccaggccagt cccctgtgtt gatcatctat gaggacaaca
      241 aacggtcttc tgggatcgct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgagtatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gcagtggtaa tggcttattc ggaggaggga cccgactgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002758             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:19485:23010
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002758
VERSION     KCWK01002758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19485:23010"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..242
                     /note="immunoglobulin light chain variable region"
     V_region        8..242
     V_segment       8..205
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <170..>214
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68496.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       208..242
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        243..>280
                     /gene="IGLC"
BASE COUNT           53 a           91 c           74 g           62 t
ORIGIN      
        1 acatgggcag cagaagccag ggagtcctcc ccggtacctt ctgtactacc agtcagactc
       61 aaggaagcac cagggctctg gagtccccag ccgcttctct ggatccaaag atgcttcagc
      121 caatgcaggg ctgttactga tctctgggct ccagtctgaa gatgaggctg actattactg
      181 tgccctctgg cacagcagcg cttcttgcat cttcggtggt gggacccggc tcaccgtcct
      241 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002759             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:16003:13045
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002759
VERSION     KCWK01002759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16003:13045"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68497.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          152 c          113 g          117 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttggtaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcatc aggggtctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002760             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:19011:17795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002760
VERSION     KCWK01002760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19011:17795"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..341
                     /note="immunoglobulin light chain variable region"
     V_region        13..341
     V_segment       13..307
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68498.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       308..341
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        342..>381
                     /gene="IGLC"
BASE COUNT           66 a          130 c           90 g           95 t
ORIGIN      
        1 acatgggggg ctcagtctgc cccgactcag cctccctctg tgtctgggtc tcctggacag
       61 tcggtcacca tctcctgcac tggaaccacc agtgacgttg gtggttctaa ctctgtctcc
      121 tggtaccaac aacacccagg caaagccccc aaactcatga tttttggtgt caataatcgg
      181 ccctctgggg tctctgaccg cttctctggc tccaagtctg gcaacacggc ctccctgacc
      241 atctctgggc tccagtctga ggacgaggct gattattact gttgttcaca ttcaaccagt
      301 agcacttacg tcttcggtcc tgggacccgg ctcaccgtcc tgggtcagcc caaggcttcc
      361 cccacggtca ctctgttccc g
//
LOCUS       KCWK01002761             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:18737:15220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002761
VERSION     KCWK01002761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18737:15220"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68499.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          155 c          120 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacgcttta ttcttcggag gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002762             450 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:19728:4444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002762
VERSION     KCWK01002762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19728:4444"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..412
                     /note="immunoglobulin light chain variable region"
     V_region        82..412
     V_segment       82..373
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68500.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       382..412
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>450
                     /gene="IGLC"
BASE COUNT           88 a          147 c          111 g          104 t
ORIGIN      
        1 acatggggac tcaggacagt ctccagcatg gcctggtctc tccttctcac tctgctggtt
       61 cactgcacag ggtcctgggc ccagtctgtg ctgacgcagc cgccctcagc atctggggcc
      121 cccggacaga gggtcaccat ctcctgcatt agcagcagct ccaacatcgg ggcggcttat
      181 tatgtatcct ggtaccaaca gttaccagga acagccccca aactcctcat ctttgaaaat
      241 aataagcgac cctcaggggt ttctgaccga ttctctggct ccaagtctgg tccctcagcc
      301 tccctgacca tcactggact ccaatctgag gatgaggctg attattactg tttagcatgg
      361 gataccagcc tgaattggat cttcggcgga gggacccggc tgaccgtcct aggtcagccc
      421 aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002763             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18145:3116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002763
VERSION     KCWK01002763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18145:3116"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68501.1"
                     /translation="DYYCAIGHYSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          157 c          115 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catacactgg taccagcaga agccagggag tcctccccga tatcttctga
      241 gatacaaatc ggactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tggcctccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacact acagcggtga ttacatcttc ggtgctggga
      421 cccgactcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002764             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:14248:17185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002764
VERSION     KCWK01002764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14248:17185"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..227
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68502.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       231..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           67 a           84 c           90 g           60 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaactaa aactgtgcac tggtaccaac agaagccacc
       61 gcagggccct gtattggtca tctttgctga tagtagacgg ccctcaggga tccctgagcg
      121 attctctggc tccaattcag ggaacaccgc caccctgacc atcagcaggg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg
      241 ggggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01002765             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:25362:18483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002765
VERSION     KCWK01002765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25362:18483"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68503.1"
                     /translation="DYYCHVYDNSTNVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          163 c          120 g          112 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctatgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtggtaaaaa catttactgg taccagcaga agccagggcg cgctcccagg
      241 tttttcctgt actacaactc cgactcagac aagcagctgg gacctggggt ccccaatcgc
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcac gtatatgaca atagtactaa tgtgttattc
      421 ggaggaggga cccgtgtgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01002766             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:9454:11127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002766
VERSION     KCWK01002766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:9454:11127"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68504.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          160 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacga tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002767             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:15917:4894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002767
VERSION     KCWK01002767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15917:4894"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68505.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          165 c          123 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagcctc
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgccgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002768             450 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:11401:9399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002768
VERSION     KCWK01002768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:11401:9399"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..412
                     /note="immunoglobulin light chain variable region"
     V_region        91..412
     V_segment       91..376
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68506.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       380..412
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>450
                     /gene="IGLC"
BASE COUNT           92 a          140 c          127 g           91 t
ORIGIN      
        1 acatggggag gcagcattga cggtgcctca gccatggcct ggacccttct cctcctcggc
       61 ctcctcgctt actgcacagg ctctgcgacc tcctatgaat tgactcagtc accctcagtg
      121 tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat tggaactaaa
      181 actgtgcact ggtaccaaca gaagccaccg cagggccctg tattggtcat ctttgctgat
      241 agtagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg gaacaccgcc
      301 accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg tcaggtgtgg
      361 gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct aggtcagccc
      421 aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002769             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:19947:9500
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002769
VERSION     KCWK01002769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19947:9500"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68507.1"
                     /translation="DYFCAAWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          159 c          122 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtccag ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaacca gctccaacat cggaagtaat agtgtgtcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat ctattataat catcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attatttctg cgcagcatgg gatgatagcc tgaccggtta cattttcggt
      421 actgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002770             401 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:25629:20028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002770
VERSION     KCWK01002770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 401)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25629:20028"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    42..363
                     /note="immunoglobulin light chain variable region"
     V_region        42..363
     V_segment       42..327
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <291..>335
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68508.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       328..363
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        364..>401
                     /gene="IGLC"
BASE COUNT           90 a          121 c          113 g           77 t
ORIGIN      
        1 acatgggcgg cctcctcgct tactgcacag gctctgcgac ctcctatgag ctgactcagg
       61 caccctcagt gtcagcggcc tcaggacaga cggccaggat cacctgtggc ggagacaaca
      121 ttggaattaa aaatgtccac tggtaccagc agaagccagc acaggcccct gtggtagtca
      181 tctatgctga taacaaacgg ccctcaggga tccctgagcg actctctggc tccaactcag
      241 ggaatattgc caccctgacc atcagcaggg tcgaggccgg ggatgaggca gactattact
      301 gtcaggtgtg ggacagtagt agtaaatggg tattcggcgg agggacccgg ctaaccgtcc
      361 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002771             318 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:17363:17266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002771
VERSION     KCWK01002771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 318)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17363:17266"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..280
                     /note="immunoglobulin light chain variable region"
     V_region        7..280
     V_segment       7..243
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>252
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68509.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       244..280
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        281..>318
                     /gene="IGLC"
BASE COUNT           65 a           97 c           85 g           71 t
ORIGIN      
        1 acatggggtg gcgtcaatgt tgctgactac cacatacact ggtaccagca gaagccaggg
       61 agtccccccc gatatcttct gaggtacaaa tcagactcag ataagggcca gggctctgga
      121 gtccccagcc gcttctctgg atccaaagat gctgcagcga acacagggat tttacgcatc
      181 tctgggctcc agtctgagga tgaggctgac tattactgtg ccattgggca cagcagcggt
      241 ccttacttct tcggtgctgg gacccggctc tccgtcctag gtcagcccaa ggcttccccc
      301 acggtcactc tgttcccg
//
LOCUS       KCWK01002772             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:14958:12087
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002772
VERSION     KCWK01002772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14958:12087"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..446
                     /note="immunoglobulin light chain variable region"
     V_region        113..446
     V_segment       113..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68510.1"
                     /translation="DYYCQSYDSNLSAMLF"
     J_segment       411..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           91 a          153 c          128 g          112 t
ORIGIN      
        1 acatgggggg cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag tgtctggggc gcccgggcag agggtcacca tctcctgcac
      181 tgggagtagt tccaacttcg gggcgggtta ttatgtgcac tggtaccagc aacttccagg
      241 aacggccccc aaactcctca tctatgaaaa caatatgcga ccctcagggg tttctgatcg
      301 attctctggc tccaagtctg gaacctcagc ctccctgacc atcactggac tccagtctga
      361 ggatgaggct gattattact gccagtccta tgacagtaat ttgagtgcta tgttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01002773             285 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:20756:17319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002773
VERSION     KCWK01002773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 285)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20756:17319"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..247
                     /note="immunoglobulin light chain variable region"
     V_region        7..247
     V_segment       7..210
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <178..>219
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68511.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       217..247
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        248..>285
                     /gene="IGLC"
BASE COUNT           56 a           88 c           84 g           57 t
ORIGIN      
        1 acatgggcca tcgcatggca tcagcagcag caagggaagg cccctcggta tttgatgtgg
       61 cttaaaagtg atggcagcca cagcaagggg gacgggatcc ctgatcgctt ctccggctcc
      121 agctccgggg ctgagcgcta cctcaccatc tccaacctcc agtctgagga tgaggctgat
      181 tattactgtc agacctggga gactggcatt caggtgttcg gcggagggac ccggctaacc
      241 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002774             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17160:16800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002774
VERSION     KCWK01002774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17160:16800"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68512.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          120 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca atcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002775             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:15329:19253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002775
VERSION     KCWK01002775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15329:19253"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68513.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           92 a          147 c          128 g           97 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct atactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002776             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:26044:4040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002776
VERSION     KCWK01002776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:26044:4040"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..305
                     /note="immunoglobulin light chain variable region"
     V_region        10..305
     V_segment       10..266
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <233..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68514.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       271..305
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           70 a          104 c           85 g           84 t
ORIGIN      
        1 acatggggtc agactcagct gcaccttgag cagtggcatc aatgttggtt cttacaccat
       61 attctggtac cagcagaagc cagggagtcc tccccggttc cttctgtact actactcaga
      121 ctcaaataat caccagggct ctggagtccc cagccgcttc tctggatcca aagatgcttc
      181 agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg ctgactatta
      241 ctgtgccatg tggcacagca gcgcttatgc cttattcgga ggagggaccc ggctgaccgt
      301 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002777             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:19999:19998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002777
VERSION     KCWK01002777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19999:19998"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68515.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          149 c          116 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcacggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002778             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:20509:4062
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002778
VERSION     KCWK01002778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20509:4062"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..314
                     /note="immunoglobulin light chain variable region"
     V_region        7..314
     V_segment       7..277
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68516.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       278..314
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           75 a          105 c           94 g           78 t
ORIGIN      
        1 acatggggga gcatcggcca gactcccctg caccctgagt agtgacctca gtgttggtag
       61 taaaaacatc tactggtacc agctgaagcc agggagcgct cccaggtcat tcctgtacta
      121 ctactccgac tcagacaagc agctgggacc tggggtcccc aatcgagtct ctggctccaa
      181 ggagacctca agtaacacag cgtttttgct catctctggg ctccagcctg aggacgaggc
      241 cgattattac tgtcaggtct atgacagtag tgctaatgtg ttattcggag gagggacccg
      301 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002779             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:19166:17569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002779
VERSION     KCWK01002779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19166:17569"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..456
                     /note="immunoglobulin light chain variable region"
     V_region        126..456
     V_segment       126..419
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68517.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       420..456
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           94 a          158 c          126 g          116 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca cttcacagtt ccagggtcct
      121 gggcccagtc tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca
      181 ccatctcctg cactgggagc agctccaaca ttggagatta ttttgtgcag tggtaccagc
      241 accttccagg aacggccccc aaactcctca tctatgaaaa taataagcgg ccctcaggga
      301 tttctgatcg attctctggc tcccagtctg gaacctcagc ctccctgacc atcactggac
      361 tccagtctga ggatgaggct gattattact gccagtccta tgacagcagt ttgattgctg
      421 tgttattcgg aggagggacc cgactgaccg tcctaggtca gcccaaggct gccccctcgg
      481 tcactctctt cccg
//
LOCUS       KCWK01002780             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:5664:10071
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002780
VERSION     KCWK01002780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5664:10071"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..357
                     /note="immunoglobulin light chain variable region"
     V_region        9..357
     V_segment       9..320
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <285..>329
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68518.1"
                     /translation="DYSCAIGHSSGPYIF"
     J_segment       321..357
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        358..>395
                     /gene="IGLC"
BASE COUNT           87 a          130 c           92 g           86 t
ORIGIN      
        1 acatgggcaa gcctatgctg actcagccgg cctccctctc agcaactcct ggagcatcag
       61 ccagtctcac atgcaccttc agcggtggca tcaatgttgc tgactaccac atacactggt
      121 accagcagaa gccagggagt cccccccggt atcttctgag ttacaaatca gactcagata
      181 agggccaggg ctctggagtc cccagccgct tctctggatc caaaaatact tcaacgaaca
      241 caggcatttt acacatctct gggctccagt ctgaggatga ggctgactat tcctgtgcca
      301 ttggacacag cagcggtcct tacatcttcg gtgctgggac ccggctcacc gtcctaggtc
      361 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002781             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:6473:19477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002781
VERSION     KCWK01002781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:6473:19477"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68519.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           91 a          153 c          118 g          110 t
ORIGIN      
        1 acatgggtgg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcata atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaagacgg cctccctgac catctctgga ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacgcttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002782             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:3495:11664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002782
VERSION     KCWK01002782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:3495:11664"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68520.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          120 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctgggttc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002783             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:9615:4919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002783
VERSION     KCWK01002783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:9615:4919"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68521.1"
                     /translation="DYYCAIWHSSASYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          161 c          112 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagctttttc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tttactacta ctcagagtca agtaaccacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002784             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:11164:14586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002784
VERSION     KCWK01002784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11164:14586"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68522.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          156 c          125 g          106 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gactccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagaaata gtgtatcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagcgggctc caggccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagcggttac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01002785             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:19252:13707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002785
VERSION     KCWK01002785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19252:13707"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68523.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          160 c          126 g          106 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggtccc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaggca cctccaacat cggaagtaat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctggccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagcgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcctgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002786             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:9226:9993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002786
VERSION     KCWK01002786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9226:9993"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68524.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           91 a          153 c          118 g          111 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat aatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaagacg gcctccctga ccatctctgg actccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaactcttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002787             375 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:16750:5433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002787
VERSION     KCWK01002787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 375)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:16750:5433"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..337
                     /note="immunoglobulin light chain variable region"
     V_region        13..337
     V_segment       13..288
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>309
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68525.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       300..337
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        338..>375
                     /gene="IGLC"
BASE COUNT           79 a          112 c          107 g           77 t
ORIGIN      
        1 acatgggcga cctcctttga gctgactcag ccaccctcgg tgtcagtggc ctcaggacag
       61 acggccagga tcacctgtgg gggagacaac attggaatta aatttgtcca ctggtaccag
      121 cagaagccag cgcaggcccc tgtgaaggtc atctatgctg atgacaaacg gccctcaggg
      181 atccctgaga gattctctgg ctccaattca gggaacaccg ccaccctgac catcagcggg
      241 gtcgaggccg gggatgaggc tgactattcc tgtcaggtgt gggacagtga gactgatcat
      301 tacatcttcg gtgttgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg
      361 gtcactctgt tcccg
//
LOCUS       KCWK01002788             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:23242:8587
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002788
VERSION     KCWK01002788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:23242:8587"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68526.1"
                     /translation="DYYCATWDDRLNGWVF"
     J_segment       395..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          150 c          125 g          104 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cctcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgttc tgactcagcc
      121 tccctcagcg tctgaggccg ccgggaagag tgtcaccatc tcctgttctg gaagcagctc
      181 caacatcgga agcaatagtg tgtcctggta ccaacagctc ccagaaacgg ctcccaaact
      241 cctcatcttt tataatgatc ggcgagcctc aggtgtctct gaccgattct ctggctccga
      301 gtctggcacg tcagcctccc tggccatcag tggactccag accgaggatg aggctgatta
      361 ttactgcgca acatgggatg ataggctgaa tggttgggtg ttcggcggag ggacccgact
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002789             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:10671:14057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002789
VERSION     KCWK01002789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10671:14057"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68527.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           86 a          162 c          124 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctccc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggtt ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta tttctgccag gtgtttgaca gtagtgttgt gttcttcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002790             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:17112:8113
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002790
VERSION     KCWK01002790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17112:8113"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68528.1"
                     /translation="DYYCHVYDSSSNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          164 c          123 g          109 t
ORIGIN      
        1 acaggggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaagc atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagccttttt gctcatctcc gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtagtaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002791             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:16910:13634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002791
VERSION     KCWK01002791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16910:13634"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68529.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          142 c          133 g           93 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacaga ctctgcgacc tcctatgaat tgactcagtc
      121 gccctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacgacat
      181 tggaactaaa actgtgcact ggtaccaaca gaagccaccg cagggccctc tattggtcat
      241 ctttgctgat agtagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taagcgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002792             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:10033:12596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002792
VERSION     KCWK01002792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10033:12596"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68530.1"
                     /translation="DYYCSSYAGSNILFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           90 a          151 c          120 g          112 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gtaatatttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002793             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:15356:17950
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002793
VERSION     KCWK01002793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15356:17950"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68531.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       395..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          156 c          120 g          102 t
ORIGIN      
        1 acatgggggg cacaggaggc agcactcagg acagtctcca gcatggcctc gtctcctctc
       61 ctcctcaccc ttttcattca ctgcacaggg tcctgggccc agtctgtgct gacacagccg
      121 ccctcagtgt ctggggcccc agggcagagg gtcaccatct cctgcactgg gagcagctcc
      181 aacattggag gttattatat atcctggtac cagcagctcc caggaacggc ccccaaactc
      241 ctcgtctatg acaataataa gcgaccctca ggggtttctg accgattctc tggctccaag
      301 tctggttcct cagccaccct gaccatcact gggctccaga ctgaggatga ggctgattat
      361 tactgccagt cctatgacag cagtctgagt gctcgggtat tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002794             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:11554:15476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002794
VERSION     KCWK01002794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:11554:15476"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68532.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       412..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           95 a          155 c          119 g          111 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggaac atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctggct accacataca ctggtaccag cagaagccag ggagtcctcc ccgatatctt
      241 ctgagataca aatcggactc agataagggc cagggctcta gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc gaacgcaggg attttacgca tctctgggct ccagtctgag
      361 gatgaggctg actattactg tgccattggg cacagcagcg gtgattatat tttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002795             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:7244:4068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002795
VERSION     KCWK01002795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7244:4068"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68533.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       398..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           86 a          157 c          117 g          113 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgcc ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaagct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtcttat aatgctgtgt cttggtacca acagcgtcca ggcaaagccc
      241 cccaactcat aatttttgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgctgctca tatgtaggca gcaacactta catcttcgat gttgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002796             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:8791:14930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002796
VERSION     KCWK01002796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8791:14930"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68534.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           93 a          152 c          122 g          102 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagac
      121 tccctcagcg tctgaggccg ccaggaagag tgtcaccatc tcctgttctg gaagcagctc
      181 caacatcgga agaaatagtg tatcctggta ccagcagctc ccaggaacag ctcccaaact
      241 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctccaa
      301 gtctggcacg tcagcctccc tggccatcag cgggctccag gccgaggatg aggctgatta
      361 ttactgcgca gcatgggatg atagcctgag cggttacatc ttcggtgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002797             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:15396:12379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002797
VERSION     KCWK01002797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15396:12379"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68535.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          162 c          110 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt actgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcgtattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctaggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002798             329 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:17500:2900
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002798
VERSION     KCWK01002798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 329)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17500:2900"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..291
                     /note="immunoglobulin light chain variable region"
     V_region        8..291
     V_segment       8..254
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <219..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68536.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       257..291
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>329
                     /gene="IGLC"
BASE COUNT           69 a          106 c           84 g           70 t
ORIGIN      
        1 acatgggggt caccatctcc tgtacccgca gcagaggcaa cattgacaat agttatgtgc
       61 agtggtacca gcagcgcccg ggcagtgccc cgaccacagt gatttacaga gataaccaaa
      121 gagcctctgg ggtccctgat cggttctctg gctccatcga cagctcctcc aactctgcct
      181 ccctcaccat ctctgggctg aagtctgagg acgaggctga ctactactgt cagtctactg
      241 atggcaacta caatcggtta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      301 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002799             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:8322:16030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002799
VERSION     KCWK01002799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8322:16030"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..386
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68537.1"
                     /translation="DYYCQSAENSAKYYIF"
     J_segment       397..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT          108 a          132 c          121 g          104 t
ORIGIN      
        1 acatgggggt gtggttctag gaggaagagc tctgggtgtc tcaccatgac ctggaccact
       61 gttctgctcc cctttctcac tctctgcaca ggctctgagg cctcctatga gctgacacag
      121 ccaccctcag tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagaaata
      181 ctggcaaaaa aatatggtca gtggttccag cagaagccag gtcaggcccc tgtgttggtg
      241 atatataaag acagtgagag gccctcaggg atccctgagc gactctctag ttccagttca
      301 ggaacaacac ttaccttgac catcactggg gcccaggcag aagatgaggc tgactattac
      361 tgtcaatcag cagagaacag tgctaagtat tatatattcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002800             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:22118:9093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002800
VERSION     KCWK01002800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22118:9093"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..313
                     /note="immunoglobulin light chain variable region"
     V_region        8..313
     V_segment       8..277
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <241..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68538.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       281..313
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>351
                     /gene="IGLC"
BASE COUNT           78 a          103 c          103 g           67 t
ORIGIN      
        1 acatgggagt caccctcagt gtcagcggcc tcaggacaga cggccaggat cacctgtggg
       61 ggagacaaca ttggaactaa aactgtgcac tggtaccagc agaagccacc gcagggccct
      121 gtattggtca tctttgctga tagtaaacgg ccctcaggga tccctgagcg attctctggc
      181 tccaactcag ggaacaccgc caccctcacc atcagcaggg tcgaggccgg ggatgaggct
      241 gactattact gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg
      301 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002801             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:15920:4584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002801
VERSION     KCWK01002801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15920:4584"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68539.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          161 c          111 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002802             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:14332:8763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002802
VERSION     KCWK01002802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14332:8763"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68540.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       385..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           89 a          143 c          125 g          102 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactcccca tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagccg gccaggatca cctgctctgg agatgtattg
      181 ccaaaaaaat atgcttattg gttccagcag aagccaggcc agtcccctgt attggtcatc
      241 tctgaggaca ccgaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtggagg atgaagctga ctactactgt
      361 tactcagcag acagtagtgg tcatggcttc ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002803             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:11175:6677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002803
VERSION     KCWK01002803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11175:6677"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68541.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       396..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           94 a          154 c          117 g          105 t
ORIGIN      
        1 acatgggggg ggtacagaag gcaggactca ggacaatctc cagcatggcc tggttccctc
       61 tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg ctgactcagc
      121 ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct ggaagcacct
      181 ccaacatcgg aagcaataat gtatcctggt accagcagct cccaggaaca gctcccaaac
      241 tcctctttta ttataatgat caacgagcct caggtgtctc tgaccgattc tcttgctcca
      301 agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat gaggctgatt
      361 attactgcgc agcatgggat gataacctga gcggctacat cttcggtgct gggacccggc
      421 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002804             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:22282:17634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002804
VERSION     KCWK01002804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22282:17634"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68542.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          154 c          120 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttcgggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag caactcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctcccagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcggcat gggatgatag cctgagcggt tacatcttcg gtggtgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002805             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:18618:3522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002805
VERSION     KCWK01002805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18618:3522"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..249
                     /note="immunoglobulin light chain variable region"
     V_region        6..249
     V_segment       6..211
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <174..>221
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68543.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       217..249
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        250..>287
                     /gene="IGLC"
BASE COUNT           58 a           85 c           89 g           55 t
ORIGIN      
        1 atgggggaag tgaagttgtg aactggtacc agcagaagcc agcgcacgcc cctgtgctgg
       61 tcatctatgc taatagcgaa cggccctcag ggatccctga gcgattctct ggctccaaat
      121 cagggaacac ggccaccctg accatcagcg gggtcgaggc cgggggtgag gctgactatt
      181 actgtcaggt gtgggacatg cgtagtgatc aaccgctatt cggcggaggg acccggctaa
      241 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002806             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:9730:21168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002806
VERSION     KCWK01002806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9730:21168"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..402
                     /note="immunoglobulin light chain variable region"
     V_region        78..402
     V_segment       78..363
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <327..>374
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68544.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       370..402
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        403..>440
                     /gene="IGLC"
BASE COUNT           79 a          144 c          127 g           90 t
ORIGIN      
        1 acatgggcgg tgcctcagcc atggcctgga cttttctcct cctcggcctc cttgcttact
       61 gcacagactc tgcggcctcc catgatctga ctcagccacc ctcggtgacc gtgtccccag
      121 gacagacggc caggatcacc tgcgggggag acaagattcg aagtgaagtt gtgaactggt
      181 accagcagaa gccagcgcag gcccctgtat tggtcatctt tgctgatacc gaacggcccg
      241 cagggatccc cgagcgattc tctggctcca aatcagggaa cacggccacc ctgaccatcc
      301 gcggggtcga ggccggggat gaggctgact tttactgtca ggtgtgggac attcgtagtg
      361 atcgtccgct attcggcgga gggacccggc tcaccgtcct aggtcagccc aaggctgccc
      421 cctcggtcac tctcttcccg
//
LOCUS       KCWK01002807             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:10515:13041
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002807
VERSION     KCWK01002807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:10515:13041"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68545.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           90 a          156 c          119 g          108 t
ORIGIN      
        1 acatgggggg ggatctcacg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tatgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc cggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt attcttcggg ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002808             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:18951:7016
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002808
VERSION     KCWK01002808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18951:7016"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68546.1"
                     /translation="DYYCSSYGGSNTLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           90 a          152 c          120 g          111 t
ORIGIN      
        1 acatggggtt ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catcacctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatggaggca gcaatacttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002809             510 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:18443:6433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002809
VERSION     KCWK01002809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 510)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18443:6433"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    142..472
                     /note="immunoglobulin light chain variable region"
     V_region        142..472
     V_segment       142..433
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <400..>444
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68547.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       442..472
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        473..>510
                     /gene="IGLC"
BASE COUNT          101 a          158 c          138 g          113 t
ORIGIN      
        1 acatggggga agaggggcag ggagagattt ggggaagctc tgcttcagct gtgggcacag
       61 gaggcagcac tcaggacagt ctccagcatg gcctggtctc tccttctcac tctgctggtt
      121 cactgcacag ggtcctgggc ccagtctgtg ctgacgcagc cgccctcagc atctggggcc
      181 cccggacaga gggtcaccat ctcctgcatt agcagcagct ccaacatcgg ggcggcttat
      241 tatgtatcct ggtaccaaca gttcccagga acagccccca aactcctcat ctttgaaaat
      301 aataagcgac cctcaggggt ttctgaccga ttctctggct ccaagtctgg tccctcagcc
      361 tccctgacca tcactggact ccaatctgag gatgaggctg attattactg tttagcatgg
      421 gataccagcc tgaattggat cttcggcgga gggacccggc tgaccgtcct aggtcagccc
      481 aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002810             345 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:13754:11294
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002810
VERSION     KCWK01002810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 345)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13754:11294"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..307
                     /note="immunoglobulin light chain variable region"
     V_region        8..307
     V_segment       8..258
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <232..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68548.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       270..307
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>345
                     /gene="IGLC"
BASE COUNT           75 a           99 c          100 g           71 t
ORIGIN      
        1 acatgggcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
       61 attggaatta aatttgtcca ctggtaccag cagaagccag cgcaggcccc tgtgaagttc
      121 atctatgctg atgacaaacg gccctcaggg atccctgaga gattctctgg ctccaattca
      181 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgattattcc
      241 tgtcaggtgt gggacagtga gactgattat tacatcttcg gtactgggac ccggctcacc
      301 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002811             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:21913:6247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002811
VERSION     KCWK01002811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21913:6247"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68549.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           86 a          161 c          124 g          112 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggtt ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta tttctgccag gtgtttgaca gtagtgttgt gttcttcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002812             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:4464:8359
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002812
VERSION     KCWK01002812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:4464:8359"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68550.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          160 c          112 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agtgctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002813             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:7535:11850
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002813
VERSION     KCWK01002813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7535:11850"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68551.1"
                     /translation="DYYCQSSHSRVNHPFF"
     J_segment       395..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          103 a          137 c          123 g          100 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagacctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaacact
      181 ggcaaaaaaa tatgctcagt ggttccagca gaagccaggc caggcccctg tgttggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacagtt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcatcg cacagcaggg ttaatcatcc gtttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002814             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:23480:17576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002814
VERSION     KCWK01002814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23480:17576"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68552.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          139 c          136 g          104 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggaaag acggccagga tcacctgtgg gggagacaat
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgggc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tattgatcat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002815             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:15721:17785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002815
VERSION     KCWK01002815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15721:17785"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68553.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       402..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           85 a          161 c          125 g          105 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggttat aactatgtct cctggtacca acaacatcca ggcacagccc
      241 ccaaactcgt gatttatgag gtcaatcagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tgacaacacg gcctccctga ccatctctgg cctccagcct gaggacgagg
      361 ctgattatta ctgcagctcg tatgcaggca gcgacacttt cgtgttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002816             406 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:19575:12583
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002816
VERSION     KCWK01002816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 406)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19575:12583"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    177..368
                     /note="immunoglobulin light chain variable region"
     V_region        177..368
     V_segment       177..331
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <299..>340
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68554.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       335..368
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        369..>406
                     /gene="IGLC"
BASE COUNT           73 a          134 c          102 g           97 t
ORIGIN      
        1 acatgggggc tcattcctgg ctgtggctca ggaagcagag cctggagcat ctccaccatg
       61 gcctgggctc cactcctcct caccctcctc actcactgca cagggtcttg ggctgaggtt
      121 gtgttcactc agccccattc tgtgtcgggg tctccggggc agacggtcac catctcctgt
      181 gatttacaaa gataaccaaa gaccctctgg ggtccctgat cggttctctg gctccatcga
      241 cagctcctcc aactctgcct ccctcaccat ctctggactg aaatctgagg acgaggctga
      301 ctattactgt cagtcttatg acagcagcag tgtattattc ggaggaggga cccggctgac
      361 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002817             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17257:8606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002817
VERSION     KCWK01002817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17257:8606"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..343
                     /note="immunoglobulin light chain variable region"
     V_region        13..343
     V_segment       13..299
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68555.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       313..343
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>381
                     /gene="IGLC"
BASE COUNT           75 a          118 c           98 g           90 t
ORIGIN      
        1 acatgggggg ctcaggctgc cccgactcag actccctctg tgtccgggtc tcctggacag
       61 tcggtcacca tctcctgcac tggaaccagc agtgatattg ggtattatca tgctgtgtct
      121 tggtaccagc atcatccagg caaagccccc aaactcatga tttatgaggt caataaacgg
      181 cccgcagggg tctctgatcg cttctctggc tccaagtctg gcaacacggc ctccctgacc
      241 atctctgggc tccagactga ggatgaggct gattattact gtagctcata tgcaggcagc
      301 aacagtttat tcttcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      361 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002818             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:4003:10700
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002818
VERSION     KCWK01002818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4003:10700"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68556.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          165 c          123 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagccc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002819             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:19126:5664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002819
VERSION     KCWK01002819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19126:5664"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68557.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          146 c          130 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtctc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002820             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:13784:3864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002820
VERSION     KCWK01002820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13784:3864"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68558.1"
                     /translation="DYHCQVWDLNSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          141 c          137 g          100 t
ORIGIN      
        1 acatgggggt gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcga tttcagtgtc cccaggacag acggccaggg tcacctgtgg gggagacaac
      181 attgggagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atctatgctg atagcgagcg gccctcaggg atccctgaac gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactatcac
      361 tgtcaggtgt gggaccttaa tagtcatcat ttgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002821             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:12443:15125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002821
VERSION     KCWK01002821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12443:15125"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68559.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          164 c          124 g          108 t
ORIGIN      
        1 catggggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagcctc
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002822             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:18952:14484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002822
VERSION     KCWK01002822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18952:14484"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68560.1"
                     /translation="DYYCQSYDSSLSGVLF"
     J_segment       411..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          154 c          127 g          113 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac catctcctgc
      181 agtgggagca actccaacat tggatactat tatgtgcagt ggtaccagca gcttccaggg
      241 acggccccca aactcctcat ctatgaaaat aataagcgac cctctggggt ttctgatcga
      301 ttctctggct cccagtctgg tacctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagcagtt tgagtggtgt cttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002823             364 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:19092:12894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002823
VERSION     KCWK01002823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 364)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19092:12894"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..326
                     /note="immunoglobulin light chain variable region"
     V_region        8..326
     V_segment       8..288
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <251..>298
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68561.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       290..326
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        327..>364
                     /gene="IGLC"
BASE COUNT           80 a          112 c          101 g           71 t
ORIGIN      
        1 acatggggat ctgactcagc caccctcggt gtcagtgtcc ccaggacaga cggccaggat
       61 cacctgtggg ggagacaaca ttggaagtca aagtgtgcac tggtaccagc acaagccacc
      121 gcaggcccct atactggtca tcttttatta taccgaacgg ccctcaggaa tccctgagcg
      181 attctctggc tccaaatcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      241 ggatgaggct gactattact gtcaggtgtg ggacacaact attgatcacg gcttattcgg
      301 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      361 cccg
//
LOCUS       KCWK01002824             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:28051:7654
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002824
VERSION     KCWK01002824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:28051:7654"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68562.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           81 a          157 c          128 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacgcgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattac tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002825             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:21600:12879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002825
VERSION     KCWK01002825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21600:12879"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..427
                     /note="immunoglobulin light chain variable region"
     V_region        109..427
     V_segment       109..395
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68563.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       396..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          143 c          128 g          103 t
ORIGIN      
        1 acatggggct tagctgtggg ctcagaagca gagctctggg gtgtctccac catggcctgg
       61 actcctctct ggctcaccct cctcagtctt tgcacaggtt ctatggtttc ttctgagctg
      121 actcaggacc ctgcagtgtc tgtggccttg gggcagacag tcaggattac ctgccaagga
      181 gacagcctca gaagttctta tgcaaactgg taccaacaga ggccaggcca ggcccctgtg
      241 ctggtcgtct atggtaacaa ctaccggccc tcagggatcc cagaacgatt ctctggctcc
      301 tcctcccgaa acacagcttc cttgaccatc actggggctc aggtggaaga tgaggctgac
      361 tattactgtg actcctggga cagcagggga acccaattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002826             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:22982:17980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002826
VERSION     KCWK01002826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22982:17980"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    220..423
                     /note="immunoglobulin light chain variable region"
     V_region        220..423
     V_segment       220..384
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68564.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       389..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           96 a          143 c          119 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggtgctgac ccctggccct gccccaggct
      121 cagtccccac agatcccaag ttgagcctac cctgaatcct gagcaaagcc cagacacagc
      181 ctctgggtgg gactcctggg aatgggtcct tcatcttcaa gccccctttc ctggtgatat
      241 ataaagacag tgagaggccc tcagggatcc ctgagcgatt ctctagctcc agttcaggga
      301 caacaattac cttgaccatc agtggggccc aggcagaaga tgaggctgac tattactgtc
      361 aatcagtaga cagcagtgga aatcttccgt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002827             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16644:16701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002827
VERSION     KCWK01002827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16644:16701"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..440
                     /note="immunoglobulin light chain variable region"
     V_region        112..440
     V_segment       112..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68565.1"
                     /translation="DYYCQSYDRSLNAVLF"
     J_segment       406..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>480
                     /gene="IGLC"
BASE COUNT           91 a          151 c          130 g          108 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg agattattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccagac tcctcatcta tgaaaataat aagcgacgct cagggacttc tgatcgattc
      301 tctggctccc agtctggtac ctcagcctcg ctgaccataa gtggactcca gtctgaggat
      361 gaggctgact attactgcca gtcttatgac aggagcttga atgctgtgtt attcggagga
      421 gggacccggc tgaccgtcct cggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002828             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:4626:7716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002828
VERSION     KCWK01002828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:4626:7716"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68566.1"
                     /translation="DYHCAIGHSSGPYFF"
     J_segment       406..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          159 c          116 g          106 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gtcagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgactacca cacacactgg taccaacaga agccagggag tcccccccgg tatcttctga
      241 gatacaaatc agacacagac aagggccagg ggtctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tgggttccag tctgaggatg
      361 aggctgacta tcactgtgcc attggtcaca gcagcggtcc atacttcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002829             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:26652:16656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002829
VERSION     KCWK01002829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:26652:16656"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..405
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68567.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          165 c          116 g          108 t
ORIGIN      
        1 acatgggggc ccactgtggg gaaagaggct gtgtccacca tggcctggac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctccaagc ctatgctgac tcagccggcc
      121 tccctctctg catctcctgg agcatcagcc agtctcacat gcaccttcag cggtggcatc
      181 aatgttgctg cctaccacat acactggtac cagcagaagc cagggagtcc tccccggtat
      241 cttctgagat acaaatcaga ctcagataag gaccagggct ctggagtccc cagccgcttc
      301 tctggatcca aagatgcctc agcgaacaca gggattttac gcatctctgg gctccagtct
      361 gaggatgagg ctgactacta ctgtgccatt gggcacagca gcggtgatta catcttcgct
      421 gctgggaccc gcctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002830             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:20112:20625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002830
VERSION     KCWK01002830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20112:20625"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..260
                     /note="immunoglobulin light chain variable region"
     V_region        4..260
     V_segment       4..223
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>232
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68568.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       226..260
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>298
                     /gene="IGLC"
BASE COUNT           63 a           94 c           76 g           65 t
ORIGIN      
        1 acatgggaac attgacaata gttatgtgca gtggtaccag cagcgcccgg gcagtgcccc
       61 gaccacagtg atttacagag ataaccaaag agcctctggg gtccctgatc ggttctctgg
      121 ctccatcgac agctcctcca actctgcctc cctcaccatc tctgggctga agtctgagga
      181 cgaggctgac tactactgtc agtctactga tggcaactac aatcggttat tcggaggagg
      241 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002831             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:23685:5150
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002831
VERSION     KCWK01002831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23685:5150"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68569.1"
                     /translation="DYYCCSYTTDSTYIF"
     J_segment       400..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           86 a          162 c          117 g          108 t
ORIGIN      
        1 acatgggggg gggtctcaga aggcagcgct ctcaggacgt ctccaccatg gcctggactc
       61 tgctcctcgt caccctcctc actcaaggca caggatcctg ggctcagtct gccccgactc
      121 agcctccctc tgtgtctggg tctcctggac agtccgtcac catctcctgc agtggaacca
      181 tcagtgacgt gggtggtcat aactctgtct cctggtacca acaccaccca ggcaaacccc
      241 ccaaagtcct gacttatggt gtcagtaatc gggcctcagg ggtctctgac cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgttgttca tatacaaccg atagcactta catcttcggt agtgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002832             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:14442:21833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002832
VERSION     KCWK01002832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14442:21833"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68570.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          158 c          123 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgcg gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002833             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:17524:17919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002833
VERSION     KCWK01002833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17524:17919"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..436
                     /note="immunoglobulin light chain variable region"
     V_region        107..436
     V_segment       107..400
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68571.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       405..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>475
                     /gene="IGLC"
BASE COUNT           95 a          157 c          117 g          106 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gataatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagt tccagggtcc tgggcccagt ctgtgctgac
      121 tcagccaccc tcagcgtctg ggactcccgg gcagagtgtc accatctcgt gctctggaag
      181 cagctccaac attggaacta attatgtata ctggtaccaa cacctcccag gaacggcccc
      241 caaactcctc atctattata gtaatcagcg accctcaggg gtccctgacc gattctctgg
      301 ctctaagtct ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc
      361 tgattattac tgtgcagcat gggataacag cctgaccagt ccggtattcg gaggagggac
      421 ccggctgacc gtcctaagtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002834             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:20409:8481
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002834
VERSION     KCWK01002834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20409:8481"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..445
                     /note="immunoglobulin light chain variable region"
     V_region        112..445
     V_segment       112..403
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <367..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68572.1"
                     /translation="DYYCQSSDGSLSVHVLF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          155 c          127 g          111 t
ORIGIN      
        1 acatgggggc ttcatctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tcgtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacacagc cgccctcagt gtctggggcc ccaggggaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacgttgg aggttattat gtatactggt accagcaggt cccaggaatg
      241 gcccccaaac tcctcattta tgacaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggtac ctcagcctcc ctgaccatca ctgggctcca gactgaggat
      361 gaggctgatt attactgcca gtcctctgac ggcagcctga gtgttcatgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002835             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:6123:9003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002835
VERSION     KCWK01002835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6123:9003"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..430
                     /note="immunoglobulin light chain variable region"
     V_region        85..430
     V_segment       85..393
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68573.1"
                     /translation="DYFCQVFDDNAVLF"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          157 c          114 g          108 t
ORIGIN      
        1 acatggggag aggtagccgt gtccaccatg gccctgactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctcccagcct gtgctgactc agccaccctc cctgtctgca
      121 tccccgggag catcggccag actcccctgc accctgagca gtgacctcag tgttggaagt
      181 aaaaacatat actggtacca gcagaagcca gggagcgctc ccaggttatt cctgtactac
      241 tactccgact cagacaagca cctgggacct ggggtcccca atcgagtctc tggctccaag
      301 gagacctcaa gtcatacagc gtttttgctc atttctgggc tccagcctga ggacgaggcc
      361 gattatttct gtcaggtgtt tgacgataat gctgtattat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002836             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:25615:12623
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002836
VERSION     KCWK01002836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:25615:12623"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68574.1"
                     /translation="DYYCAMWNSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          158 c          113 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggaaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002837             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:19623:5292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002837
VERSION     KCWK01002837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19623:5292"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..423
                     /note="immunoglobulin light chain variable region"
     V_region        93..423
     V_segment       93..386
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68575.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       390..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           87 a          146 c          119 g          109 t
ORIGIN      
        1 acatggggga ggcagcactc aggacagtct ccagcatggc ctggtctcct ctcctcctca
       61 cccttctcat tcactgcaca gggtcctggg cccagtctgt gctgacgcag ccgccctcag
      121 tgtctggggc gcccgggcag agggtcatca tctcctgcac tgggagcagc tccaacattg
      181 gagattatta tgtgcagtgg taccagcagc ttccaggaac ggcccccaaa ctcctcatct
      241 atgaaaatca taagcgaccc tcaggggttt ctgatcgatt ctctggctcc cagtctggta
      301 cttcagcctc cctgaccatc actggactcc agtctgagga tgaggctgat tattactgcc
      361 agtcctatga cagtagtttg agtgctgtat tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002838             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10572:10168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002838
VERSION     KCWK01002838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10572:10168"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68576.1"
                     /translation="DYYCQVWDINSHHLLF"
     J_segment       393..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          142 c          140 g           98 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgacgca
      121 gccaccctcg atttcagtgt ccccaggaca gacggccagg ctgacctgtg ggggagacaa
      181 cattggaagt gaagttgtga actggtacca gcagaggcca ccgcaggccc ctgtgttggt
      241 catctatgct gacagcgagc ggccctcagg gatccctgag cgattctctg gctccaagtc
      301 agggaacacg gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacatta atagtcatca tctgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002839             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:21739:11389
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002839
VERSION     KCWK01002839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21739:11389"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68577.1"
                     /translation="DYYCAIGHMSGNYVF"
     J_segment       409..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          155 c          118 g          112 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacacacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatataa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acatgagcgg taattatgtc ttcggttctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002840             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:14475:22620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002840
VERSION     KCWK01002840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14475:22620"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..411
                     /note="immunoglobulin light chain variable region"
     V_region        63..411
     V_segment       63..374
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68578.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       375..411
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           86 a          150 c          112 g          101 t
ORIGIN      
        1 acatgggggc cctgactcct ctcctcctcc tgctcctctc tcactgcaca ggttccctct
       61 cccagcctgt gctgactcag ccaccctccc tgtctgcatc cccgggagca tcggccagac
      121 tcccctgcac cctgagcagt gacctcagtg ttggtggtaa aaacatgtac tggtaccagc
      181 agaagccagg gagcgctccc aggttattcc tgttctacca gtccgactca gacaagcagc
      241 tgggacctgg ggtccccaat cgagtctctg gctccaagga gacctcaagt aacacagcgt
      301 ttttgttcat ctctggactc cagcctgagg acgaggccga ttattactgt caggtgtatg
      361 acagtagtgc aaatgtgtta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcaca ctcttcccg
//
LOCUS       KCWK01002841             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:17025:5084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002841
VERSION     KCWK01002841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17025:5084"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..404
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68579.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          157 c          122 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagtagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002842             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:23698:3264
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002842
VERSION     KCWK01002842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23698:3264"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68580.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          143 c          141 g           94 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggttctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccag cgcaggcccc tgtgctggtc
      241 atctatgctg atagcgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg ggggtgaggc tgactattac
      361 tgtcaggtgt gggacatgcg tagtgatcaa ccgctattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002843             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:17926:14891
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002843
VERSION     KCWK01002843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17926:14891"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68581.1"
                     /translation="DYYCQSADSSGNYPFF"
     J_segment       398..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          134 c          126 g          100 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaac
      181 actggcaaaa aaatatggtc agtggttcca gcagaagcca ggccaggtcc ctgtgttggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgaatctcta gctctagttc
      301 agggacaaca cttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagca gtggaaatta tccgttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002844             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:12026:17085
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002844
VERSION     KCWK01002844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12026:17085"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..279
                     /note="immunoglobulin light chain variable region"
     V_region        8..279
     V_segment       8..243
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68582.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       247..279
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>317
                     /gene="IGLC"
BASE COUNT           70 a           90 c           95 g           62 t
ORIGIN      
        1 acatgggggc caggatcacc tgtgggggag acaacattgg aactaaaact gtgcactggt
       61 accaacagaa gccaccgcag ggccctgtat tggtcatctt tgctgatagt agacggccct
      121 cagggatccc tgagcgattc tctggctcca actcagggaa caccgccacc ctgaccatca
      181 gcagggtcga ggccggggat gaggctgact attactgtca ggtgtgggac agtagtagta
      241 aatggatatt cggcgggggg acccggctaa ccgtcctagg tcagcccaag gctgccccct
      301 cggtcactct cttcccg
//
LOCUS       KCWK01002845             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:11362:5771
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002845
VERSION     KCWK01002845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11362:5771"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68583.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          138 c          136 g          103 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcggcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002846             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:16391:15385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002846
VERSION     KCWK01002846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16391:15385"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..441
                     /note="immunoglobulin light chain variable region"
     V_region        111..441
     V_segment       111..404
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68584.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       408..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           87 a          159 c          125 g          108 t
ORIGIN      
        1 acatggggat tcctggctgt ggctcaggaa gcagagcctg gagcatctcc accatggcct
       61 gggctccact cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt
      121 tcactcagcc ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc
      181 gcagcagtgg cagcattgac aacggctttg tgtactggta ccagcagcgg ccgggcagcg
      241 ctcccaccac tgtgatttac aaagataacc aaagaccctc tggggtccct gatcggttct
      301 ctggctccat cgacagctcc tccaactctg cctccctcac catctctgga ctgaaatctg
      361 aggacgaggc tgactattac tgtcagtctt atgacagcag cagtgtatta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002847             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:24960:14793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002847
VERSION     KCWK01002847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:24960:14793"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68585.1"
                     /translation="DYYCGIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          156 c          118 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cacgggtggc atcaatgttg
      181 ctgactacca catacactgg taccagctga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtggc attgggcaca gcagcggtga ttacatcttc gctgatggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002848             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:14581:7050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002848
VERSION     KCWK01002848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14581:7050"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68586.1"
                     /translation="DYYCQSGDSSGNHWVF"
     J_segment       392..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          103 a          133 c          128 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgtcaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actgactaaa aaatatactc tgtggttcca gcagaggcca ggccaggccc ctctggtggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag agattctcta gttccagttc
      301 agggccaaca gctaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca ggagacagca gtggtaatca ttgggtattc ggcggaggga cccggctaag
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002849             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:9357:9449
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002849
VERSION     KCWK01002849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9357:9449"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..395
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <351..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68587.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       396..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           92 a          150 c          132 g           96 t
ORIGIN      
        1 acatggggcc tggcttcaga agcagcatct gggacatgtc agccatggcc tggacgcctc
       61 tcctcctcag cctcctcgct cactgcacag gctctgtggc ctcctatgag ctgactcagc
      121 caccctcagt gtcggtgtcc ccaggacaga cagccagcat cacctgctct ggaaataaat
      181 tggggaatgt atatgcttac tggttccagc agaagccagg ccaggcccct gtagtggtca
      241 tctacaaaga taccaaccgg ccctcaggga tccctgagcg attctctggc tccgactcag
      301 ggaacacggc caccctgacc atcagcaggg tcgaggctgg ggatgaggcc gactattttt
      361 gtgctgcagc ctatggcagt ggcagcagct ggcagtgggt attcggcgga gggacccggc
      421 taatcgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002850             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:21343:16891
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002850
VERSION     KCWK01002850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:21343:16891"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68588.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg tcagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002851             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:5749:18433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002851
VERSION     KCWK01002851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5749:18433"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68589.1"
                     /translation="DYYCQVWDSSSDHVFF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          145 c          135 g           93 t
ORIGIN      
        1 acatgggggg gcctcaggaa gcagccttgg cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcggcc tcctatgata tgactcagcc
      121 acgctcagtg tctgtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tagaagtaaa aatgtgaatt ggtaccagca gaagccaccg caggcccccg cgctggtcat
      241 ctattatgat agcgaccggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtgatcatgt gtttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002852             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:10054:8267
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002852
VERSION     KCWK01002852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10054:8267"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..382
                     /note="immunoglobulin light chain variable region"
     V_region        58..382
     V_segment       58..344
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <307..>354
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68590.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       350..382
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>420
                     /gene="IGLC"
BASE COUNT           81 a          131 c          123 g           85 t
ORIGIN      
        1 acatggggga cttttctcct cctcggcctc cttgcttact gcacaggctc tgcggcctcc
       61 tatgatctga ctcagccacc ctcggtgtca gtgtccccag gacagacggc caggatcacc
      121 tgcgggggag acaagattgg aagtgaagtt gtgaactggt accagcagaa gccagcgcac
      181 gcccctgtgc tggtcatcta tgctaatagc gaacggccct cagggatccc tgagcgattc
      241 tctggctcca aatcagggaa cacggccacc ctgaccatca gcggggtcga ggccgggggt
      301 gaggctgact attactgtca ggtgtgggac atgcgtagtg atcaaccgct attcggcgga
      361 gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002853             339 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:8101:2582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002853
VERSION     KCWK01002853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 339)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8101:2582"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..301
                     /note="immunoglobulin light chain variable region"
     V_region        8..301
     V_segment       8..261
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <229..>273
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68591.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       264..301
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        302..>339
                     /gene="IGLC"
BASE COUNT           71 a          101 c           90 g           77 t
ORIGIN      
        1 acatggggtc tcacatgcac cttcagcggt ggcatcaatg ttgttggcta ccacatacac
       61 tggtaccagc agaagccagg gagtcctccc cggtatcttc tgagatacaa atcggactca
      121 gataagggcc agggctctgg agtccccagc cgcttctctg gatccaaaga tgcttcagcg
      181 aacgcaggga ttttacgcat ctctggactc cagtctgagg atgaggctga ctattactgt
      241 gccattgggc acagcagcgg tgattacatc ttcggtgctg ggacccggct caccgtccta
      301 ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002854             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:17349:19770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002854
VERSION     KCWK01002854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17349:19770"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..421
                     /note="immunoglobulin light chain variable region"
     V_region        76..421
     V_segment       76..384
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68592.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       385..421
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           84 a          159 c          111 g          105 t
ORIGIN      
        1 acatgggccg tgtccaccat ggccctgact cctctcctcc tcctgctcct ctctcactgc
       61 acaggttccc tctcccagcc tgtgctgact cagccaccct ccctgtctgc atccccggga
      121 gcatcggcca gactcccctg caccctgagc agtgacctca gtgttggtaa taaaaacctc
      181 tactggtacc agcagaagcc agggagcgct cccaggttat tcctgtacta ctactccgac
      241 tcagacaagc agctgggacc tggggtcccc aatcgagtct ctggctccaa ggagacctca
      301 agtcatacag cgtttttgct catctctggg ctccagcctg aggacgaggc cgattattac
      361 tgtcaggtgt atgacagtag tgctgtgtta ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002855             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:6121:13644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002855
VERSION     KCWK01002855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:6121:13644"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68593.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          160 c          114 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgctgctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002856             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:10590:7189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002856
VERSION     KCWK01002856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10590:7189"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    70..394
                     /note="immunoglobulin light chain variable region"
     V_region        70..394
     V_segment       70..351
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <319..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68594.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       364..394
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>432
                     /gene="IGLC"
BASE COUNT           82 a          141 c          123 g           86 t
ORIGIN      
        1 acatgggcag ccatggcctg gacccttctc ctcctcggcc tcctcgctca ctgcacaggc
       61 tctgcgacct cctatgagct gactcagcca ccctcggtgt cagcggcctc aggacagacg
      121 gccaggatca cctgtggggg agacaacatt ggaactaaat atgtgcactg gtaccagcag
      181 aagccagcgc aggcccctgt gttggtcatc tatgctgata ccagacggcc ctcagggatc
      241 cctgagcgat tctctggctc caactcagga aacaccgcca ccctgaccat cagcggggtc
      301 gaggccgggt atgaggctga ctatttctgt caggtgtggg acgatagtag tgatcatccg
      361 gtgttcggcg gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      421 actctcttcc cg
//
LOCUS       KCWK01002857             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:18612:8214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002857
VERSION     KCWK01002857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18612:8214"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68595.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       409..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           90 a          151 c          129 g          114 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctctccttc tcactctgct ggttcactgc acagggtcct gggcccagtc
      121 tgtgttgacg cagccgccct cagcatctgg ggcccccggg cagagggtca ccatctcctg
      181 cactgggagt agctccaaca tcggggcggg tttttatgtt tcctggtacc agcagttccc
      241 aggaacagcc cccaaactcc tcatctttga aaataataag cgaccctcag gggtttctga
      301 ccgattctct ggctccaagt ctggttcctc agcctccctg accatcactg gactccaatc
      361 tgaggatgag gctgattatt attgttcatc atgggaaagc agcctgaatt gggtattcgg
      421 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01002858             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:13306:24285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002858
VERSION     KCWK01002858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:13306:24285"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..254
                     /note="immunoglobulin light chain variable region"
     V_region        8..254
     V_segment       8..217
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68596.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       218..254
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           57 a           94 c           74 g           67 t
ORIGIN      
        1 acatgggggt ggttataact atgtctcctg gtaccaacaa catccaggca cagcccccaa
       61 actcgtgatt tatgaggtca atcagcggcc ctcaggggtc tctgatcgct tctctggctc
      121 caagtctgac aacacggcct ccctgaccat ctctggcctc cagcctgagg acgaggctga
      181 ttattactgc agctcgtatg caggcagcga cactttcgtg ttattcggag gagggacccg
      241 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002859             332 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14556:14478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002859
VERSION     KCWK01002859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 332)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14556:14478"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..294
                     /note="immunoglobulin light chain variable region"
     V_region        8..294
     V_segment       8..258
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>266
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68597.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       262..294
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>332
                     /gene="IGLC"
BASE COUNT           72 a           95 c          101 g           64 t
ORIGIN      
        1 acatgggggc ctcaggacag ccggccagga tcacctgtgg gggagacaac attggaatta
       61 aaactgtgca ctggtaccag cagaagccac cgcagggccc tgtattggtc atctttgctg
      121 atagtaaacg gccctcgggg atccctgagc gattctctgg ctccaactca gggaacaccg
      181 ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac tgtcaggtgt
      241 gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc ctaggtcagc
      301 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002860             323 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:10087:20393
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002860
VERSION     KCWK01002860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 323)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10087:20393"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..285
                     /note="immunoglobulin light chain variable region"
     V_region        8..285
     V_segment       8..236
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <210..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68598.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       248..285
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>323
                     /gene="IGLC"
BASE COUNT           71 a           93 c           93 g           66 t
ORIGIN      
        1 acatggggac ggccaggatc acctgtgggg gagacaacat tggaattaaa tttgtccact
       61 ggtaccagca gaagccagcg caggcccctg tgaaggtcat ctatgctgat gacaaacggc
      121 cctcagggat ccctgagaga ttctctggct ccaattcagg gaacaccgcc accctgacca
      181 tcagcggggt cgaggccggg gatgaggctg actattcctg tcaggtgtgg gacagtgaga
      241 ctgattatta catcttcggt actgggaccc ggctcaccgt cctaggtcag cccaaggctt
      301 cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002861             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:20079:20900
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002861
VERSION     KCWK01002861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20079:20900"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68599.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       391..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          138 c          141 g           98 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactttac aggctctgcg gcctcctatg aggtgactca
      121 gccacgctca gtgtccgtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt aaaagtgtgc agtggtacca gcagacgcca ccgcaggccc ctgtactggt
      241 catttatggt gatagggaac ggccctcagg gatccctgag cgattctctg gttccaactc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggatagta gtagtaaata tgtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002862             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:24206:16000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002862
VERSION     KCWK01002862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24206:16000"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68600.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          157 c          121 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctgt gctgactcag ccggcctccc
      121 tctcagcatc tcctggggca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagtcagg gagtcctccc cggtatcttc
      241 taagatacaa atcagactca gatcagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacgggga ttttacacgt ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002863             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:8840:4240
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002863
VERSION     KCWK01002863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:8840:4240"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68601.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       392..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          140 c          136 g          101 t
ORIGIN      
        1 acatggggct gactttggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 acctcctcgg cctccttgct cactttacag gctctgtggc ctcctatgag ttgcctcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa tagtgtgcat tggtaccagc agaagccacc gcgggcccct gtattggtca
      241 tctctgttga tagcgaacgg ccctcaggga tccctgagcg attctctggt tccagatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggataatatt tataaatacg cggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002864             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:16903:10687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002864
VERSION     KCWK01002864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16903:10687"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68602.1"
                     /translation="DYYCSSWESSLNWIF"
     J_segment       408..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          154 c          129 g          110 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg gttcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agcatctggg gcccccgggc agagggttac catctcctgc
      181 actgggagca gctccaacat cggggcgggt ttttatgtgt cctggtacca acagttccct
      241 ggaacagccc ccaaactcct catctatgaa aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggttcctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgctcatca tgggaaagca gcctgaattg gatattcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002865             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:16467:19809
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002865
VERSION     KCWK01002865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16467:19809"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68603.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          157 c          121 g          110 t
ORIGIN      
        1 acatgggggc agcctcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgttgactc agcctccctc agcgtctgag gccgccggga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtatcct ggtaccaaca actcccagaa
      241 acggctccca aactcctcat gtattataat catcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacttcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagtatgg gatgatagcc tgaccggtta catcttcggt
      421 actgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002866             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16159:6237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002866
VERSION     KCWK01002866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16159:6237"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68604.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          162 c          112 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggccga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002867             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:18454:4037
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002867
VERSION     KCWK01002867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18454:4037"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68605.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       408..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           89 a          163 c          120 g          108 t
ORIGIN      
        1 acatggggca ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcgtcaat
      181 gtgggtagtt acagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
      241 ctgtactacc agtcagactc aaggaagcac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc caatgcaggg ctgttactga tctctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccctctgg cacagcagcg cttcttgcat cttcggtggt
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002868             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:14927:10777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002868
VERSION     KCWK01002868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14927:10777"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68606.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          150 c          115 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctacccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002869             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:21993:8737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002869
VERSION     KCWK01002869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21993:8737"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68607.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          160 c          114 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 ggtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002870             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:12592:19306
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002870
VERSION     KCWK01002870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12592:19306"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..455
                     /note="immunoglobulin light chain variable region"
     V_region        110..455
     V_segment       110..418
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68608.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       419..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           93 a          169 c          121 g          110 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      181 gagcagtgac ctcagtgttg gtaataaaaa catgtactgg taccaacaga agccagggag
      241 cgctcccagg ttattcctgt actactattc cgactcagac aagcagctgg gacctggggt
      301 cccccatcga gtctctggct ccaaggagac ctcaactaac acagcgtttt tgctcatctc
      361 tgggctccag cctgaggacg aggccgatta ctactgtcag gtgtatgaca gtagtgctgt
      421 gttattcgga ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01002871             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:20508:21547
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002871
VERSION     KCWK01002871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20508:21547"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68609.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           91 a          147 c          128 g           96 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtcaaa gtgtgcactg gtaccagcac aagccaccgc aggcccctgt actggtcatc
      241 ttttattata ccgaacggcc ctcaggaatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acacaactat tgatcacggc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002872             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:23203:12309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002872
VERSION     KCWK01002872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23203:12309"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68610.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       402..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          150 c          122 g          114 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggttcaggct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatgt tgggtattat aacgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 ccaaactcat gatttatgac gtcattaagc ggccctcagg ggtttctgat cgcttctctg
      301 gctccaagtc tggcgacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gaaataattt tttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002873             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:26192:12714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002873
VERSION     KCWK01002873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:26192:12714"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..431
                     /note="immunoglobulin light chain variable region"
     V_region        106..431
     V_segment       106..396
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68611.1"
                     /translation="DYYCQSADGNYRVF"
     J_segment       397..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>470
                     /gene="IGLC"
BASE COUNT           86 a          162 c          122 g          100 t
ORIGIN      
        1 acatgggggg tgactcagaa agcagagcct ggggcgtctc caccatggcc tgggctccac
       61 tcctcctcac cctcctcgct cactgcacag ggtcttgggc tgaacttgtg ttcactcagc
      121 cccattctgt gtcggggtct ccggggcaga cggtcaccat ctcctgcacc cgcagcattg
      181 gcaacattga cagtgaatat gtgcagtggt accagcagcg cccgggcagt gcccccacca
      241 cactgattta caaagatagt caaagaccct ctggggtccc tgaccggttc tctggctcca
      301 tcgacagctc ctccaactct gcctccctcg ccatctctgg gctacagtct gaggacgagg
      361 ctgactacta ctgtcagtct gctgatggca actacagggt cttcggcgga gggacccggc
      421 taaccgtcct aagtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002874             409 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:14427:14539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002874
VERSION     KCWK01002874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 409)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 409)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14427:14539"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    41..371
                     /note="immunoglobulin light chain variable region"
     V_region        41..371
     V_segment       41..332
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <296..>343
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68612.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       334..371
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        372..>409
                     /gene="IGLC"
BASE COUNT           78 a          129 c          106 g           96 t
ORIGIN      
        1 acatgggacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc tgacgcagcc
       61 gccctcagtg tctggggcgc ccgggcagag ggtcaccctc tcctgcactg ggagcagctc
      121 caacattgga gattattatg tgcagtggta ccagcagctt ccaggaacgg cccccaaact
      181 cctcatctat gaaaataata agcgaccctc aggggtttct gatcgattct ctggctccca
      241 gtctggtacc tcagcctccc tgaccatcac tggactccag tctgacgatg aggctgatta
      301 ttactgtcag tcctatgata gcagcctgag tgttgtgtta ttcggaggag ggacccggct
      361 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002875             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:17678:11202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002875
VERSION     KCWK01002875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:17678:11202"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68613.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          155 c          125 g          106 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggtacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcaga ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct
      181 ggaagcagct ccaacatcgg aagaaatagt gtatcctggt accagcagct cccaggaaca
      241 gctcccaaac tcctcatcta ttatagtgat caacgagcct caggtgtctc tgaccgattc
      301 tctggctcca agtctggcac gtcagcctcc ctggccatca gcgggctcca ggccgaggat
      361 gaggctgatt attactgcgc agcatgggat gatagcctga gcggttacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002876             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14100:22336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002876
VERSION     KCWK01002876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14100:22336"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..389
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68614.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       394..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          156 c          118 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agtctcaggt gtctctgacc gattctctgg ctcccagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggacgatag cctgcgcggc tatatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002877             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:17501:8615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002877
VERSION     KCWK01002877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:17501:8615"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68615.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          154 c          122 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg ctcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002878             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:13211:4569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002878
VERSION     KCWK01002878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13211:4569"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68616.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          157 c          118 g          111 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggaacatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgtctacca cgtacactgg taccaacaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggggt ccccagccgc ttctctggat
      301 ccagtaatgc ttcagcgaac acagggattt tacgcatttc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtct ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002879             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:18927:18469
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002879
VERSION     KCWK01002879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:18927:18469"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68617.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       392..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          147 c          138 g           93 t
ORIGIN      
        1 acatggggtg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag gctctgcgac ctcctatgag ctggctcagc
      121 caccctcggt gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa ctatgtgcac tggtaccagc agaagccagc gcaggcccct gtagagatta
      241 tctttgctga taacaaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggatcaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactatttct
      361 gtcaggtgtg gggcagtcgt agtgatcatc cggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002880             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:15136:5024
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002880
VERSION     KCWK01002880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15136:5024"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68618.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          161 c          123 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagt gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002881             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:25673:17524
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002881
VERSION     KCWK01002881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:25673:17524"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..425
                     /note="immunoglobulin light chain variable region"
     V_region        97..425
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68619.1"
                     /translation="DYYCAAWDDSLSGGLF"
     J_segment       391..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>465
                     /gene="IGLC"
BASE COUNT           88 a          153 c          121 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag ccgctccaac
      181 atcggaagta atagtgtatc ctggtaccag cagctcccag gaactgctcc caaactcctc
      241 atctattatg atgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtctg cctccctggc catcagtggg ctccagaccg acgatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagcggt ggcttattcg gaggagggac ccggctgacc
      421 gtcctcggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002882             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:18164:6443
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002882
VERSION     KCWK01002882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18164:6443"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..248
                     /note="immunoglobulin light chain variable region"
     V_region        8..248
     V_segment       8..212
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>220
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68620.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       216..248
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        249..>286
                     /gene="IGLC"
BASE COUNT           62 a           83 c           84 g           57 t
ORIGIN      
        1 acatggggga actaaaactg tgcactggta ccagcagaag ccaccgcagg gccctgtatt
       61 ggtcatcttt gctgatagta aacggccctc agggatccct gagcgattct ctggctccaa
      121 ctcagggaac accgccaccc tgaccatcag cagggtcgag gccggggatg aggctgacta
      181 ttactgtcag gtgtgggaca gtagtagtaa atggatattc ggcgggggga cccggctaac
      241 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002883             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:18898:7778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002883
VERSION     KCWK01002883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:18898:7778"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68621.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          160 c          116 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgttgccta ccacatacac tggtaccagc agaagccagg gagtcccccc cgatatcttc
      241 tgaggtacaa atcagactca gataagggcc agggcgctgg agtccccagc cgcttctctg
      301 gatccaataa tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tccttacatc ttcggtgctg
      421 ggacccgtct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002884             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:14517:13222
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002884
VERSION     KCWK01002884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:14517:13222"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..441
                     /note="immunoglobulin light chain variable region"
     V_region        120..441
     V_segment       120..405
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68622.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       409..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          150 c          136 g           97 t
ORIGIN      
        1 acatggggga aggcacctgc cctgtctggg tctcaggagg cagcattgac ggtgcctcag
       61 ccatggcctg gacccttctc ctcctcggcc tcctcgctta ctgcacaggc tctgcgacct
      121 cctatgaatt gactcagtca ccctcagtgt cagcggcctc aggacagccg gccaggatca
      181 cctgtggggg agacaacatt ggaactaaaa ctgtgcactg gtaccaacag aagccaccgc
      241 agggccctct attggtcatc tttgctgata gtagacggcc ctcagggatc cctgagcgat
      301 tctctggctc caactcaggg aacaccgcca ccctgaccat cagcagggtc gaggccgggg
      361 atgaggctga ctattactgt caggtgtggg acagtagtag taaatggata ttcggcgggg
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002885             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:25837:10810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002885
VERSION     KCWK01002885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:25837:10810"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68623.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       390..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           92 a          146 c          120 g          106 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagaactct gggtcctctc caccatggcc tggacccctc
       61 ccctgctcat cctcctcact ctctgcacag gttccgtggt ttcctctgag ctgactcagg
      121 agcctgcatt gtctgtggcc ttgggacata cagtcaggat gacctgccaa ggagacagcc
      181 tcaaaaccta ttatgcaagc tggtaccagc agaagccagg ccaggtccct gtgctggtca
      241 tctatggtaa caactaccgg ccctcaggga tcccaggccg attctctgtc tcctggtcag
      301 gaaacacagg ttccttgacc atcactgcgg ctcaggtgga agatgaggct gactattatt
      361 gtaagtcctg ggacagcagt ggtacccatt acatcttcgg tgctgggacc cggctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01002886             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:26451:18032
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002886
VERSION     KCWK01002886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:26451:18032"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..436
                     /note="immunoglobulin light chain variable region"
     V_region        103..436
     V_segment       103..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68624.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       400..436
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           84 a          162 c          124 g          104 t
ORIGIN      
        1 catggggggg gtctcaggag gcagcgctct cgggacatct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 cctcgctcag tgtctgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgacatcg gtggttataa ctatgtctcc tggtaccaac aacatccagg cacagccccc
      241 aaactcgtga tttatgaggt caatcagcgg ccctcagggg tctctgatcg cttctctggc
      301 tccaagtctg acaacacggc ctccctgacc atctctggcc tccagcctga ggacgaggct
      361 gattactact gcagctcgta tgcaggcagc gacactttcg tgttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002887             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:13659:7828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002887
VERSION     KCWK01002887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13659:7828"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..423
                     /note="immunoglobulin light chain variable region"
     V_region        97..423
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68625.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>465
                     /gene="IGLC"
BASE COUNT           86 a          152 c          121 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctctcagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccaggccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag tctgagcggt tacatcttcg gtgctgggac ccggctcgcc
      421 gtcgtaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002888             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:17883:4218
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002888
VERSION     KCWK01002888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17883:4218"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68626.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>460
                     /gene="IGLC"
BASE COUNT           95 a          140 c          123 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctctgtg tcagtgtccc caggacagac ggccaagatc acctgctctg gagatgcact
      181 gccaaaaaaa tttgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 cgatgaagac agtaaacggc cctctgggat ccctgagaga atctctggct ccagttcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002889             450 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:27073:7029
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002889
VERSION     KCWK01002889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:27073:7029"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..412
                     /note="immunoglobulin light chain variable region"
     V_region        88..412
     V_segment       88..375
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68627.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       376..412
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>450
                     /gene="IGLC"
BASE COUNT           90 a          145 c          114 g          101 t
ORIGIN      
        1 acatggggag aactctgggt cctctccacc atggcctgga cccctcccct gctcatcctc
       61 ctcactctct gcacaggttc cgtggtttcc tctgagctga ctcaggagcc tgcattgtct
      121 gtggccttgg gacaaacagt caggatgacc cgccaaggag acagcctcaa aacctattat
      181 gcaagctggt accagcagaa gccaggccag gtccctgtgc tggtcatcta tggtaacaac
      241 taccggccct cagggatccc aggccgattc tctgtctcct ggtcaggaaa cacaggttcc
      301 ttgaccatca ctgcggctca ggtggaagat gaggctgact attactgtaa gtcctgggac
      361 agcagtggta cccattacat cttcggtgct gggacccggc tcaccgtcct aggtcagccc
      421 aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002890             321 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:20447:4094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002890
VERSION     KCWK01002890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 321)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20447:4094"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..283
                     /note="immunoglobulin light chain variable region"
     V_region        9..283
     V_segment       9..246
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>255
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68628.1"
                     /translation="DYFCQVWDSISDHPLF"
     J_segment       249..283
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>321
                     /gene="IGLC"
BASE COUNT           68 a           93 c           96 g           64 t
ORIGIN      
        1 acatgggggg ccaggatcac ctgtggggga gacaacattg gaactaaata tgtgcactgg
       61 taccagcaga agccagcgca ggcccctgtg caggtcattt atggtgatac caaacggccc
      121 tcagggatcc ctgagcgatt ctctggctcc aactcaggga acaccgccac cctgaccatc
      181 agcggggtcg aggccgggga tgaggctgac tatttctgtc aggtgtggga cagtattagt
      241 gatcatccct tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      301 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002891             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:13900:16671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002891
VERSION     KCWK01002891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13900:16671"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..441
                     /note="immunoglobulin light chain variable region"
     V_region        96..441
     V_segment       96..402
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68629.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       404..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           86 a          160 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcccagcc tgtgctgact cagccaccct
      121 ccctgtctgc atccccggga gcatcggcca gactcccctg caccctgagc agtgacctca
      181 gtgttggtag taaaaacatg tactggtacc agcagaagcc agggagcgct cccaggttat
      241 tcctgtacta ctactccgac tcagacaagc agctgggacc tggggtcccc aatcgagtct
      301 ctggctccaa ggagacctca agtaacacag cgtttttgct catctctggg ctccagcctg
      361 aggacgaggc cgattatttc tgccaggtgt ttgacagtag tgttgtgttc ttcggaggag
      421 ggacccgact gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002892             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:9487:16390
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002892
VERSION     KCWK01002892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9487:16390"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..309
                     /note="immunoglobulin light chain variable region"
     V_region        8..309
     V_segment       8..269
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>281
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68630.1"
                     /translation="DYYCQVWDISTDHPVLF"
     J_segment       273..309
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        310..>347
                     /gene="IGLC"
BASE COUNT           73 a           99 c          104 g           71 t
ORIGIN      
        1 acatgggggt gtcagtgtcc ccaggacaga cggccagggt cacctgtgga ggagacaacc
       61 ttggatatga agttgtcaac tggtaccagc agaagccacc gcaggcccct gtggtggtca
      121 tctatgctga ttatgaacgg ccctcaggga tccctaaccg attctctggc tccaaatcag
      181 ggaacacggc caccctgacc atcagcggag tcgaggccgg ggatgaggct gactattatt
      241 gtcaggtgtg ggacattagt actgaccatc cggtgttatt cggaggaggg acccggctga
      301 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002893             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:20677:9210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002893
VERSION     KCWK01002893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:20677:9210"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..277
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68631.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       278..314
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           78 a          110 c           85 g           79 t
ORIGIN      
        1 acatggggga gcatcagcca gtctcacatg caccttcagc ggtggcatca atgttgttgc
       61 ctaccacata cactggtacc agcagaagcc agggagtccc ccccggtatc ttctgagtta
      121 caaatcagac tcagataagg gccagggctc tggagtcccc agccgcttct ctggatccaa
      181 aaatgcttca acaaacacag gcattttaca catctctggg ctccagtctg aggatgaggc
      241 tgactatttc tgtgccattg gacacagcag cggtccttac atcttcggtg ctgggacccg
      301 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01002894             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:29297:13527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002894
VERSION     KCWK01002894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:29297:13527"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68632.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          151 c          116 g          107 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ccacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002895             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:28906:15454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002895
VERSION     KCWK01002895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:28906:15454"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68633.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          147 c          131 g           96 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gtactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgggcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002896             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:13185:4838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002896
VERSION     KCWK01002896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13185:4838"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..439
                     /note="immunoglobulin light chain variable region"
     V_region        93..439
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68634.1"
                     /translation="DYYCSIGHSSGLYIF"
     J_segment       404..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>479
                     /gene="IGLC"
BASE COUNT           90 a          159 c          116 g          114 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcaccggt ggcatcaatg
      181 ttgctgtcta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtttcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgaggctga ctattactgt tccattggac acagcagcgg tctttacatc ttcggtgctg
      421 ggacccggct caccgtcctg ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002897             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:5447:7779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002897
VERSION     KCWK01002897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5447:7779"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <349..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68635.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           92 a          149 c          131 g           96 t
ORIGIN      
        1 acatgggctg gcttcagaag cagcatctgg gacatgtcag ccatggcctg gacgcctctc
       61 ctcctcagcc tcctcgctca ctgcacaggc tctgtggcct cctatgagct gactcagcca
      121 ccctcagtgt cggtgtcccc aggacagaca gccagcatca cctgctctgg aaataaattg
      181 gggaatgtat atgcttactg gttccagcag aagccaggcc aggcccctgt agtggtcatc
      241 tacaaagata ccaaccggcc ctcagggatc cctgagcgat tctctggctc cgactcaggg
      301 aacacggcca ccctgaccat cagcagggtc gaggctgggg atgaggccga ctatttttgt
      361 gctgcagcct atggcagtgg cagcagctgg cagtgggtat tcggcggagg gacccggcta
      421 atcgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002898             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:16857:17550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002898
VERSION     KCWK01002898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16857:17550"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68636.1"
                     /translation="AYYCQVWDGDSDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          149 c          129 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gactctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcaacggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaagccag cgcaggcccc tatgcaggtc
      241 atctatgctg ataacaaacg gccctcaggg atccctgaga gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctattac
      361 tgtcaggtgt gggacggtga tagtgatcat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002899             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:25529:5911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002899
VERSION     KCWK01002899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:25529:5911"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68637.1"
                     /translation="DYFCAAWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          159 c          122 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtccag ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggatcca gctccaacat cggaagtaat agtgtgtcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat ctattataat catcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attatttctg cgcagcatgg gatgatagcc tgaccggtta cattttcggt
      421 actgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002900             328 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:13690:22712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002900
VERSION     KCWK01002900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 328)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13690:22712"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..290
                     /note="immunoglobulin light chain variable region"
     V_region        7..290
     V_segment       7..253
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>262
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68638.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       254..290
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        291..>328
                     /gene="IGLC"
BASE COUNT           75 a           99 c           86 g           68 t
ORIGIN      
        1 acatggggga caaacagtca ggatgacctg ccaaggagac agcctcaaaa cctattatgc
       61 aagctggtac cagcagaagc caggccaggt ccctgtgctg gtcatctatg gtaacaacta
      121 ccggccctca gggatcccag gccgattctc tgtctcctgg tcaggaaaca caggttcctt
      181 gaccatcact gcggctcagg tggaagatga ggctgactat tactgtaagt cctgggacag
      241 cagtggtacc cattacatct tcggtgctgg gacccggctc accgtcctag gtcagcccaa
      301 ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01002901             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:21089:4741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002901
VERSION     KCWK01002901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21089:4741"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..282
                     /note="immunoglobulin light chain variable region"
     V_region        8..282
     V_segment       8..233
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68639.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       245..282
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>320
                     /gene="IGLC"
BASE COUNT           69 a           92 c           92 g           67 t
ORIGIN      
        1 acatgggggc caggatcacc tgtgggggag acaacattgg aattaaattt gtccactggt
       61 accagcagaa gccagcgcag gcccctgtga aggtcatcta tgctgatgac aaacggccct
      121 cagggatccc tgagagattc tctggctcca attcagggaa caccgccacc ctgaccatca
      181 gcggggtcga ggccggggat gaggctgact attcctgtca ggtgtgggac agtgagactg
      241 attattacat cttcggttct gggacccggc tcaccgtcct aggtcagccc aaggcttccc
      301 ccacggtcac tctgttcccg
//
LOCUS       KCWK01002902             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:5035:7722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002902
VERSION     KCWK01002902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:5035:7722"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..404
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68640.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          156 c          124 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggcg ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagtagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002903             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:24889:17702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002903
VERSION     KCWK01002903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:24889:17702"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68641.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       409..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          154 c          128 g          113 t
ORIGIN      
        1 acatgggggt ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca ccatctcctg
      181 cactgggagc agctccaaca ttggaggtta ttatgtgcag tggtaccagc agcttccagg
      241 aacggccccc aaactcctca tctatgaaaa tgataaacga ccctcagggg tttctgatcg
      301 attctctggc tcccagtctg attcctcagc ctccctgacc atcactggac tccagtctga
      361 ggatgaggct gattattact gccagtccta tgacagcagc ttgagtgttg tgttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01002904             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:17318:19843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002904
VERSION     KCWK01002904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:17318:19843"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68642.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          155 c          128 g          111 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgagtc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtttcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagtc tgagcggata catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002905             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:5233:10621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002905
VERSION     KCWK01002905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:5233:10621"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68643.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       415..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          157 c          122 g          110 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg gttcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agcatctggg gcccccggac agaggatcac catctcctgc
      181 attagcagca gctccaacat cggggcggct tattatgtat cctggtacca acagttccca
      241 ggaacagccc ccaaactcct catctttgaa aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggtccctca gcctccctga ccatcactgg actccaatct
      361 gaggatgagg ctgattatta ctgtttagca tgggatacca gcctgaattg gatcttcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002906             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:6519:13383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002906
VERSION     KCWK01002906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:6519:13383"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68644.1"
                     /translation="DYYCQVWDSSSDHWIF"
     J_segment       392..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           92 a          148 c          136 g           91 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca cagactctgc gacctcctat gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taaatatgtg cactggtacc agcagaggcc accgcaggcc cctgtgcaag
      241 tcatctatac tgatagcaga cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg cggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attggatatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002907             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:20571:3118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002907
VERSION     KCWK01002907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20571:3118"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..414
                     /note="immunoglobulin light chain variable region"
     V_region        101..414
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68645.1"
                     /translation="DYFCQSGDSSGNHWVF"
     J_segment       389..414
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>463
                     /gene="IGLC"
BASE COUNT          105 a          129 c          130 g           99 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gaaaaatact
      181 ggcaaaaaaa tatactcagt ggttccagca gaagccaggc caggcccctc tgctggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagaga ttttctaggt ccagttcagg
      301 gccaagggat agcttgacca tcagtggggc ccaggcagaa gatgaggctg actatttctg
      361 tcaatcagga gacagcagtg gtaatcattg ggtattcggc ggagggaccc ggctaggcgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002908             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:11773:3097
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002908
VERSION     KCWK01002908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11773:3097"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..229
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68646.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       233..269
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           65 a           85 c           92 g           65 t
ORIGIN      
        1 acatggggga ggagacaaca ttggaagtga agttgtcaac tggtaccagc agaggccacc
       61 gcaggcccct gtgctggtca tctatgctga ttatgaacgg ccctcaggga tccctgagcg
      121 attctctggc tccaaatcag ggaacacggc caccctgacc atcagcggag tcgaggccgg
      181 ggatgaggct gactattatt gtcaggtgtg ggacatttat attgaccatc cggtgttatt
      241 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01002909             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:15907:7094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002909
VERSION     KCWK01002909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15907:7094"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..390
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68647.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       391..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           82 a          160 c          122 g          101 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 actctcctcc ttcactgcac agggtctctc tcccagcctg tgctgactca gtcgccctct
      121 gcctctgcct ccctgggagc ctcggtcaag ctcacctgca ctctgagcag tggccactac
      181 agctacacca tcgcatggca tcagcagcag caagggaagg cccctcggtt cttgatgtgg
      241 cttaagagtg atggcagcca caccaagggg gacggggtcc ctgatcgctt ctcaggctcc
      301 agctccgggg ctgagcgcta cctcaccatc tccaacctcc agtctgagga tgaggctgat
      361 tattactgtc agacctggga tattggcatt tgggtattcg gcggagggac ccggctaatc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002910             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:12467:20189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002910
VERSION     KCWK01002910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12467:20189"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..418
                     /note="immunoglobulin light chain variable region"
     V_region        102..418
     V_segment       102..388
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68648.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       389..418
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>458
                     /gene="IGLC"
BASE COUNT           89 a          141 c          128 g          100 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagagctct ggggtgtctc caccatggcc tggactcctc
       61 tctggctcac cctcctcagt ctttgcacag gttctatggt ttcttctgag ctgactcagg
      121 accctgcagt gtctgtggcc ttgggacaga cagtcaggat tacctgccaa ggagacagcc
      181 tcagaagctc ttatgcaagc tggtaccaac agaggccagg ccaggcccct gtgctggtcg
      241 tctatggtaa caactaccgg ccctcaggga tcccagagcg attctctggc tcctactcac
      301 gaaacacagc ttccttgacc atctctgggg ctcaggtgga agatgaggct gactattact
      361 gtgactcctg ggacagcagc ggaacccaat tcggaggagg gacccggctg accgtcctgg
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002911             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:26425:18011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002911
VERSION     KCWK01002911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:26425:18011"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..403
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68649.1"
                     /translation="DYYCASYEGSNTFLF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          159 c          122 g          106 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcagtggaac
      181 cagcagtaag attgggtatc acaatgctgt gtcctggtac caagagcatc caggcaaagc
      241 ccccaaactc atgatttatg acgtcaataa gcggccctca gggatctctg atcgcttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccagc ctgatgatga
      361 gggtgattat tactgcgcct catatgaagg cagcaacact ttcctcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002912             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:22825:20060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002912
VERSION     KCWK01002912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22825:20060"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68650.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          164 c          119 g          114 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atttactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgcg
      301 tctctggctc caaggagact tcaagtaaca cagcgttttt gctcatctct ggcctccagc
      361 ctgaggacga ggccgattat tactgtcacg tttatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002913             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:17799:4008
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002913
VERSION     KCWK01002913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17799:4008"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..432
                     /note="immunoglobulin light chain variable region"
     V_region        84..432
     V_segment       84..395
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68651.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       398..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           91 a          158 c          115 g          106 t
ORIGIN      
        1 acatgggaga ggtagccgtg tccaccatgg ccctgactcc tctcctcctc ctgctcctct
       61 ctcactgcac aggttccctc tcccagcctg tgctgactca gccaccctcc ctgtctgcat
      121 ccccgggagc atcggccaga ctcccctgca ccctgagcag tgacctcagt gttggtagta
      181 aaaacatgta ctggtaccaa cagaagccag ggagcgctcc caggttattc ctgtactact
      241 actccgactc agacaagcag ctgggacctg gggtccccaa tcgagtctct ggctccaagg
      301 agacctcaag taacacagcg tttttgctca tctctgggct ccagcctgag gacgaggccg
      361 attattactg tcaggtgtat gacagtagtg ctaatgtctt attcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002914             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:22061:10009
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002914
VERSION     KCWK01002914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22061:10009"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68652.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           89 a          152 c          122 g          110 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgtagctca tatgcaggca gcaacagttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002915             497 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:14359:11879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002915
VERSION     KCWK01002915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 497)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 497)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..497
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14359:11879"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    129..459
                     /note="immunoglobulin light chain variable region"
     V_region        129..459
     V_segment       129..420
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>431
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68653.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       422..459
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        460..>497
                     /gene="IGLC"
BASE COUNT           93 a          155 c          133 g          116 t
ORIGIN      
        1 acatggggag atttggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga
       61 cagtctccag catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt
      121 cctgggccca gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg
      181 tcaccatctc ctgcactggg agcagctcca acattggagg ttattatgtg cagtggtacc
      241 agcagcttcc aggaacggcc cccaaactcc tcatctatga aaatgataaa cgaccctcag
      301 gggtttctga tcgattctct ggctcccagt ctgattcctc agcctccctg accatcactg
      361 gactccagtc tgaggatgag gctgattatt actgccagtc ctatgacagc agcttgagtg
      421 ttgtgttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct
      481 cggtcactct cttcccg
//
LOCUS       KCWK01002916             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12110:10825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002916
VERSION     KCWK01002916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12110:10825"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68654.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       411..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          151 c          128 g          116 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt cagtatttct
      181 tgcactggga gcagctccaa cattggaggt tattatgtgc agtggtacca gcagcttcca
      241 ggaacggccc ccaaactcct catctatgaa aatgataaac gaccctcagg gatttctgat
      301 cgattctctg gctcccagtc tgattcctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gcttgagtgt tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01002917             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:18876:18337
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002917
VERSION     KCWK01002917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18876:18337"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68655.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          152 c          123 g          113 t
ORIGIN      
        1 acaggggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggttcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt ataacgctgt gtcttggtac caacagcatc caggcaaagc
      241 ccccaaactc ataatttttg acgtcattaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccggg ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagaaataat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002918             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:10361:22975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002918
VERSION     KCWK01002918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10361:22975"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68656.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          160 c          113 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggcgt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002919             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:4554:15069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002919
VERSION     KCWK01002919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:4554:15069"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..248
                     /note="immunoglobulin light chain variable region"
     V_region        8..248
     V_segment       8..212
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>220
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68657.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       216..248
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        249..>286
                     /gene="IGLC"
BASE COUNT           62 a           82 c           84 g           58 t
ORIGIN      
        1 acatggggga attaaaactg tacactggta ccagcagaag ccaccgcagg gccctgtatt
       61 ggtcatcttt gctgatagta agcggccctc agggatccct gagcgattct ctggctccaa
      121 ctcagggaac accgccaccc tgaccatcag cagggtcgag gccggggatg aggctgacta
      181 ttactgtcag gtgtgggaca gtagtagtaa atggatattc ggcgggggga cccggctaac
      241 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002920             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:7117:13590
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002920
VERSION     KCWK01002920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7117:13590"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..391
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68658.1"
                     /translation="DYYCQSFDSSTVLF"
     J_segment       397..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           81 a          156 c          125 g          107 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcatctcc accatggcct gggctccgct
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccaatctgtg tcggggtctc cggggcagac ggtcaccatc tccttcaccc gcagcagtgg
      181 cagcattggc aacagctatg tgtactggtt ccagcagcgg ccgggcagcg tccccactat
      241 tgtgatttac aaagatgacc aaagaccctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctgga ctgaagtctg gggacgaggc
      361 tgactattac tgtcagtctt ttgacagcag cactgtctta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002921             277 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:17835:9164
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002921
VERSION     KCWK01002921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 277)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17835:9164"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..237
                     /note="immunoglobulin light chain variable region"
     V_region        8..237
     V_segment       8..202
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <164..>211
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68659.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       205..237
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>277
                     /gene="IGLC"
BASE COUNT           50 a           86 c           83 g           58 t
ORIGIN      
        1 acatggggtg cactggtacc agcagaagcc agcgcaggcc cctgtgttgg tcatctatgc
       61 tgataccaga cggccctcag ggatccctga gcgattctct ggctccaact cagggaacac
      121 cgccaccctg accatcagcg gggtcgaggc cgggtatgag gctgactatt tctgtcaggt
      181 ttgggacgat agtagtgatc atccggtatt cggcggaggg acccggctga ccgtccttgg
      241 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002922             451 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:25295:12657
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002922
VERSION     KCWK01002922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 451)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:25295:12657"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..413
                     /note="immunoglobulin light chain variable region"
     V_region        92..413
     V_segment       92..377
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68660.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       381..413
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>451
                     /gene="IGLC"
BASE COUNT           92 a          140 c          128 g           91 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacccttc tcctcctcgg
       61 cctcctcgct tactgcacag gctctgcgac ctcctatgaa ttgactcagt caccctcagt
      121 gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca ttggaactaa
      181 aactgtgcac tggtaccaac agaagccacc gcagggccct gtattggtca tctttgctga
      241 tagtagacgg ccctcaggga tccctgagcg attctctggc tccaactcag ggaacaccgc
      301 caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg
      361 ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc taggtcagcc
      421 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002923             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:12038:16494
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002923
VERSION     KCWK01002923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12038:16494"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    66..396
                     /note="immunoglobulin light chain variable region"
     V_region        66..396
     V_segment       66..352
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <324..>368
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68661.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       366..396
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        397..>434
                     /gene="IGLC"
BASE COUNT           82 a          140 c          109 g          103 t
ORIGIN      
        1 acatgggcat ggtctgggct ctgctcctcc tcaccctcct cactcagggc acaggatcct
       61 gggctcaggc tgccccgact cagactccct ctgtgtccgg gtctcctgga cagtcggtca
      121 ccatctcctg cactggaacc agcagtgata ttgggtatta tcatgctgtg tcttggtacc
      181 agcatcatcc aggcaaagcc cccaaactca tgatttatga ggtcaataaa cggcccgcag
      241 gggtctctga tcgcttctct ggctccaagt ctggcaacac ggcctccctg accatctctg
      301 ggctccagac tgaggatgag gctgattatt actgtagctc atatgcaggc agcaacagtt
      361 tattcttcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      421 tcactctctt cccg
//
LOCUS       KCWK01002924             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:17460:12715
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002924
VERSION     KCWK01002924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:17460:12715"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..260
                     /note="immunoglobulin light chain variable region"
     V_region        6..260
     V_segment       6..227
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68662.1"
                     /translation="DYYCQVWDSSSRYILF"
     J_segment       234..260
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>302
                     /gene="IGLC"
BASE COUNT           69 a           79 c           87 g           67 t
ORIGIN      
        1 acatgggggg tgacaacatt ggaagtaata atgtacactg gtaccagcag aagccagcgc
       61 aggcccctat gttggtcatc tatggtggta gtaaacggcc ctcagggatc cctgagcgat
      121 tctctggctc caactcaggg aacaccgcca ccctgaccat cagcagggtc gaggccgggg
      181 atgaggctga ctattactgt caggtgtggg acagtagtag tagatacatt ttgttcggaa
      241 gaggcaccag gctgaccgtc atcggtcacc ccaaggcttc tcccttggtc actctgtttc
      301 cg
//
LOCUS       KCWK01002925             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:12902:2125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002925
VERSION     KCWK01002925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12902:2125"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68663.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          141 c          132 g           94 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgaat tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa actgtgcact ggtaccaaca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgat agtagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggttgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002926             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:17954:7634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002926
VERSION     KCWK01002926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17954:7634"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..258
                     /note="immunoglobulin light chain variable region"
     V_region        8..258
     V_segment       8..218
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <186..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68664.1"
                     /translation="VYYCAIGHMSGNYVF"
     J_segment       226..258
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           63 a           90 c           76 g           67 t
ORIGIN      
        1 acatgggcca cacacactgg taccagcaga agccagggag tcctccccgg tatcttctga
       61 gatataaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      121 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      181 aggctgtcta ttactgtgcc attgggcaca tgagcggtaa ctatgtcttc ggttctggga
      241 cccgcctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002927             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:12989:7055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002927
VERSION     KCWK01002927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12989:7055"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..443
                     /note="immunoglobulin light chain variable region"
     V_region        115..443
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68665.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>483
                     /gene="IGLC"
BASE COUNT           86 a          158 c          128 g          111 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtccag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagtc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctgggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01002928             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12917:7102
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002928
VERSION     KCWK01002928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12917:7102"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68666.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          149 c          122 g          107 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgta
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctctt gttctggaag catctccagc
      181 attggaagta gtgatgtatg ttggtaccag caactcccag gaacggcccc caaactcctc
      241 atcaattata gtgatcagcg actctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcct gggatagcag cctgagcagt ccggtatttg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002929             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:7318:3946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002929
VERSION     KCWK01002929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7318:3946"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68667.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           91 a          161 c          112 g          110 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttga gcagtggcac caatgttggt
      181 agttacagga tattctggta ccagcagaag ccagggagtc ctccccggta ccttctgtac
      241 tactactcag actcaactaa gcaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagccaatgc agggctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccat atggcacagc agcgcttctt gcatcttcgg tcctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01002930             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:25423:6754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002930
VERSION     KCWK01002930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25423:6754"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..232
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68668.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       233..269
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           67 a           96 c           77 g           67 t
ORIGIN      
        1 acatggggga agcagctcca acatcggaag taataatgtg tcctggtacc agcacctccc
       61 aggaacagct cccaaactcc tcatctacta taatgatcaa cgaggctcag gtgtctctga
      121 ccgattctct ggctccaagt ctggcacgtc agcctccctg gccatcagtg ggctccagac
      181 cgaggatgag gctgattatt actgcgcagc gtgggatgat agactgagca gttacatctt
      241 cgctgctggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      301 gttcccg
//
LOCUS       KCWK01002931             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:26494:12625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002931
VERSION     KCWK01002931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:26494:12625"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..410
                     /note="immunoglobulin light chain variable region"
     V_region        80..410
     V_segment       80..369
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <335..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68669.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       373..410
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>448
                     /gene="IGLC"
BASE COUNT           86 a          148 c          111 g          103 t
ORIGIN      
        1 acatgggggg acaatctcca gcatggcctg gttccctctc gtcctcaccc tcctcactca
       61 ctgtgcaggg tcctgggccc agtctgtgct gactcagcct ccctcagcgt ctgaggccgc
      121 caggaagagt gtcaccatct cctgttctgg aagcagctcc aacatcggaa gtaataatgt
      181 gtcctggtac cagcacctcc caggaacagc tcccaaactc ctcatctatt ataatgatca
      241 acgaggctca ggtgtctctg accgattctc tggctccaag tctggcacgt cagcctccct
      301 ggccatcagt gggctccaga ccgaggatga ggctgattat tactgcgcag cgtgggatga
      361 tagcctgagt agttacatct tcgctgctgg gacccggctc accgtcctag gtcagcccaa
      421 ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01002932             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:12138:13818
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002932
VERSION     KCWK01002932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12138:13818"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68670.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       402..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           91 a          159 c          111 g          113 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagt cagactcagc tgcaccttga gcagtggcat caatgttggt
      181 tcttacacca tattctggta ccagcagaag ccagggagtc ctccccggtt ccttctgtac
      241 tactactcag actcaaataa tcaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagccaatgc aggcctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccat gtggcacagc agcgcttatg ccttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002933             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:11092:11544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002933
VERSION     KCWK01002933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11092:11544"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68671.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       411..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          164 c          121 g          108 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagcctccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cactgacctc
      181 agtgttggtg gtaaaaacat gtactggtac cagcagaagc caggaagcgc tcccaggtta
      241 ttgctgtatt accactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcaggtg tatgacagta gtgccaacac gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01002934             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:22995:17353
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002934
VERSION     KCWK01002934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22995:17353"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..431
                     /note="immunoglobulin light chain variable region"
     V_region        110..431
     V_segment       110..395
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68672.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       399..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           92 a          146 c          134 g           97 t
ORIGIN      
        1 acatgggggc cctgtctggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggcc tcctcgctta ctgcacagtc tctgcgacct cctatgaact
      121 gactcagtca ccctcagtgt cagcggcctc aggacagccg gccaggatca cctgtggggg
      181 agacaacatt ggaattaaaa ctgtgcactg gtaccagcag aagccaccgc agggccctgt
      241 attggtcatc tttgctgata gtaaacggcc ctcggggatc cctgagcgat tctctggctc
      301 caactcaggg aacaccgcca ccctgaccat cagcagggtc gaggccgggg atgaggctga
      361 ctattactgt caggtgtggg acagtagtag taaatggata ttcggcgggg ggacccggct
      421 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002935             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:12567:5696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002935
VERSION     KCWK01002935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12567:5696"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68673.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          153 c          114 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgttgac tcagcctccc
      121 tcagcgtctg aggccgccgg gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta atagtgtatc ctggtaccaa caactcccag aaacggctcc caaactcctc
      241 atgtattata atcatcggcg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcccttcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagtat gggatgatag cctgaccggt tacatcttcg gtactgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002936             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12712:15239
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002936
VERSION     KCWK01002936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12712:15239"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68674.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          155 c          121 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gttgactcag ccggcctccc
      121 tctcagcgtc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcagacgca gataatggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tggttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002937             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:25398:7878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002937
VERSION     KCWK01002937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:25398:7878"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68675.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          143 c          132 g           93 t
ORIGIN      
        1 acatgggctg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag ggtctgcgac ctcctatgaa ctgactcagt
      121 caccctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa aactgtgcac tggtaccagc agaagccacc gcagggccct gtattggtca
      241 tctttgctga tagtaaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002938             455 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:13684:11617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002938
VERSION     KCWK01002938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 455)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13684:11617"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..417
                     /note="immunoglobulin light chain variable region"
     V_region        87..417
     V_segment       87..382
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <345..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68676.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       384..417
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>455
                     /gene="IGLC"
BASE COUNT           83 a          147 c          114 g          111 t
ORIGIN      
        1 acatggggcg ctctcaggac ttctccacca tggtctgggc tctgctcctc ctcaccctcc
       61 tcactcaggg cacaggatcc tgggttcagg ctgccccgac tcagcctccc tctgtgtccg
      121 ggtctcctgg acagtcggtc accatctcct gcactggaac cagcagtgat gttgggtatt
      181 ataacgctgt gtcttggtac caacagcatc caggcaaagc ccccaaactc atgatttatg
      241 acgtcattaa gcggccctca ggggtttctg atcgcttctc tggctccaag tctggcgaca
      301 cggcctccct gaccatctct gggctccagg ctgaggatga ggctgattat tactgcagct
      361 catatgcagg cagaaataat tttttattcg gaggagggac ccggctgacc gtcctaggtc
      421 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002939             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:14596:13887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002939
VERSION     KCWK01002939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14596:13887"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68677.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       384..419
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>458
                     /gene="IGLC"
BASE COUNT           95 a          140 c          122 g          101 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctctgtgtc agtgtcccca ggacagacgg ccaagatcac ctgctctgga gatgcactgc
      181 caaaaaaatt tgcttattgg ttccagcaga agccaggcca gtcccctgtg ttgatcatcg
      241 atgaagacag taaacggccc tctgggatcc ctgagagaat ctctggctcc agttcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcagcaga cagcagtggt tatggcttat tcggaggagg gacccggctg accgtcctac
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002940             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:13089:3255
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002940
VERSION     KCWK01002940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13089:3255"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68678.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           94 a          161 c          108 g          110 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctacacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggaacatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt cctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002941             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20479:5181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002941
VERSION     KCWK01002941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20479:5181"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68679.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          122 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaaataaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002942             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:10485:15631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002942
VERSION     KCWK01002942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10485:15631"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68680.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       215..251
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           62 a           83 c           84 g           60 t
ORIGIN      
        1 acatggggga agtaaaaatg tgcactggta ccagcaggag ccaccgcagg cccctgtgtt
       61 ggtcatcttt tatgataaca aacggccctc agggatccct gagcgattct ctggctccaa
      121 atcagggaac atcgccaccc tgaccatcag cgaggccgag gccggggatg aggctgacta
      181 ttactgtcag ctgtgggaca gtagtgttga tcatggctta ttcggaggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002943             284 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:9818:18666
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002943
VERSION     KCWK01002943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 284)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9818:18666"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..246
                     /note="immunoglobulin light chain variable region"
     V_region        7..246
     V_segment       7..206
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <174..>218
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68681.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       209..246
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        247..>284
                     /gene="IGLC"
BASE COUNT           56 a           85 c           79 g           64 t
ORIGIN      
        1 acatggggta ccagcagaag tctgggagtc ctccccggta tcttctaaga tacaaatcag
       61 actcggatca gggccagggc tctggggtcc ccagccgctt ctctggatcc aaagatgctt
      121 cagcgaacac ggggatttta cacgtctctg ggctccagtc tgaggatgag gctgactatt
      181 actgtgccat tgggcacagc agcggtgatt acatcttcgg tgctgggacc cggctcaccg
      241 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01002944             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:18354:16591
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002944
VERSION     KCWK01002944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18354:16591"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..394
                     /note="immunoglobulin light chain variable region"
     V_region        64..394
     V_segment       64..357
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <319..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68682.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       358..394
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>432
                     /gene="IGLC"
BASE COUNT           76 a          143 c          111 g          102 t
ORIGIN      
        1 acatgggtgg cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg
       61 gcccagtctg tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtctcc
      121 atctcctgtt ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcaa
      181 gtcccaggaa cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc
      241 tctgaccgat tctctggctc tcagtctggc acgtcagcct ccctggccat cagtgggctc
      301 cagaccgagg atgaggctga ttattactgc gcagcatggg atgatagcct gaggggttac
      361 atcttcggtg ctgggacccg gctcgccgtc ctaggtcagc ccaaggcttc ccccacggtc
      421 actctgttcc cg
//
LOCUS       KCWK01002945             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:6505:7844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002945
VERSION     KCWK01002945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:6505:7844"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..454
                     /note="immunoglobulin light chain variable region"
     V_region        109..454
     V_segment       109..417
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68683.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       418..454
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           93 a          168 c          121 g          110 t
ORIGIN      
        1 acatgggggc ccaaccctgg gtctgtggcc tcagaggtag ccgtgtccac catggccctg
       61 actcctctcc tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg
      121 actcagccac cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg
      181 agcagtgacc tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc
      241 gctcccaggt tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc
      301 cccaatcgag tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct
      361 gggctccagc ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtg
      421 ttattcggag gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCWK01002946             379 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:22260:12804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002946
VERSION     KCWK01002946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 379)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 379)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..379
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22260:12804"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..341
                     /note="immunoglobulin light chain variable region"
     V_region        20..341
     V_segment       20..305
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <269..>313
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68684.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       306..341
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        342..>379
                     /gene="IGLC"
BASE COUNT           87 a          111 c          109 g           72 t
ORIGIN      
        1 acatgggggc tctgcgacct cctatgagct gactcaggca ccctcagtgt cagcggcctc
       61 aggacagacg gccaggatca cctgtggcgg agacaacatt ggaattaaaa atgtccactg
      121 gtaccagcag aagccagcac aggcccctgt ggtagtcatc tatgctgata acaaacggcc
      181 ctcagggatc cctgagcgac tctctggctc caactcaggg aatattgcca ccctgaccat
      241 cagcagggtc gaggccgggg atgaggcaga ctattactgt caggtgtggg acagtagtag
      301 taaatgggta ttcggcggag ggacccggct aaccgtccta ggtcagccca aggctgcccc
      361 ctcggtcact ctcttcccg
//
LOCUS       KCWK01002947             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10375:11780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002947
VERSION     KCWK01002947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10375:11780"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68685.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          156 c          120 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagtcagg gagtcctccc cggtatcttc
      241 taagatacaa atcagactca gatcagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacgggga ttttacacgt ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002948             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:10554:2376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002948
VERSION     KCWK01002948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10554:2376"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68686.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       408..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          163 c          111 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtatcagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacta ctccgactca agcaagcacc aggcctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccacatggc acagcagcgc ttcttatatc ttcggttctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002949             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:10713:19371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002949
VERSION     KCWK01002949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10713:19371"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68687.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          162 c          115 g          111 t
ORIGIN      
        1 acatgggggc tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcagtg
      181 ttggtactta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacca ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcaggtc tgttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002950             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:16889:4281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002950
VERSION     KCWK01002950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:16889:4281"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..254
                     /note="immunoglobulin light chain variable region"
     V_region        8..254
     V_segment       8..215
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68688.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       217..254
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           61 a           85 c           72 g           74 t
ORIGIN      
        1 acatgggatt ggagattatt atgtgcagtg gtaccagcag cttccaggaa cggcccccaa
       61 actcctcatc tatgaaaata ataagcgacc ctcaggggtt tctgatcgat tctctggctc
      121 ccagtctggt acctcagcct ccctgaccat cactggactc cagtctgacg atgaggctga
      181 ttattactgt cagtcctatg atagcagcct gagtgttgtg ttattcggag gagggacccg
      241 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002951             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:8013:20386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002951
VERSION     KCWK01002951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8013:20386"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68689.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       411..447
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           95 a          158 c          124 g          108 t
ORIGIN      
        1 acatgggggc gcagcttcag ctgtgggtac agaaggcagg actcaggaca atctccagca
       61 tggcctggtt ccctctcgtc ctcaccctcc tcactcactg tgcagggtcc tgggcccagt
      121 ctgtgctgac tcagcctccc tcagcgtctg aggccgccag gaagagtgtc accatctcct
      181 gttctggaag cagctccaac atcggaagta ataatgtgtc ctggtaccag cacctcccag
      241 gaacagctcc caaactcctc atctattata atgatcaacg aggctcaggt gtctctgacc
      301 gattctctgg ctccaagtct ggcacgtcag cctccctggc catcagtggg ctccagaccg
      361 aggatgaggc tgattattac tgcgcagcgt gggatgatag cctgagcagt tacatcttcg
      421 ctgctgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt
      481 tcccg
//
LOCUS       KCWK01002952             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:10415:3317
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002952
VERSION     KCWK01002952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:10415:3317"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68690.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       403..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           90 a          159 c          114 g          114 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtac tgacccagcc aacctccctc
      121 tcagcatctc cgggagcatc agccagactc agctgcacct tgagcagtgg catcaatgtt
      181 ggtagttaca gcgtattctg gtaccagcag aagccaggga gtcctccccg gttccttctg
      241 tactactact cagactcaag taaacaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcggccaa tgcaggcctt ttactgatct ctggggtcca gtctgaggat
      361 gaggctgact attactgtgc catatggcac agcagcgctt cttacttctt cggtactggg
      421 acccggttca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01002953             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:20294:16609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002953
VERSION     KCWK01002953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20294:16609"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..303
                     /note="immunoglobulin light chain variable region"
     V_region        6..303
     V_segment       6..268
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68691.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       273..303
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           71 a          101 c           87 g           82 t
ORIGIN      
        1 acatggggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc agtgatattg
       61 ggtattatca tgctgtgtct tggtaccagc atcatccagg caaagccccc aaactcatga
      121 tttatgaggt caataaacgg cccgcagggg tctctgatcg cttctctggc tccaagtctg
      181 gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct gattattact
      241 gcagctcata tggaggcagc aatagtttat tcttcggagg agggacccgg ctgaccgtcc
      301 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01002954             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:12240:6782
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002954
VERSION     KCWK01002954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12240:6782"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68692.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          158 c          126 g          110 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccgggaa gagtgtctcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc tcagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagcggttac atcttcggtg
      421 ctgggacccg gctcgccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01002955             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:25525:12051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002955
VERSION     KCWK01002955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:25525:12051"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68693.1"
                     /translation="DYYCQVWDSSSDHYIF"
     J_segment       394..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          149 c          133 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccaggg tcacctgtgg gggagacaac
      181 attggaacta cgtttgtgca ctggtaccag cagaatccac cgcaggcccc tgtgcaggtc
      241 atctttgcgg atgacaaacg accctcaggg atccctgaac gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtgatcat tatatcttcg gtggtgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01002956             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:16095:13605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002956
VERSION     KCWK01002956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16095:13605"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..440
                     /note="immunoglobulin light chain variable region"
     V_region        92..440
     V_segment       92..401
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68694.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       403..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           94 a          153 c          116 g          115 t
ORIGIN      
        1 acatgggact gcagggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc gcagcctgtg ctgactcagc caacctccct
      121 ctcagcttct cctggagcat cagccagact cacctgcacc ttgagcagtg gcatcagtgt
      181 tggtacttac aggatattct ggtaccagca gaggccaggg agtcctcccc ggtatcttct
      241 gaaccaccac acagactcag ataaacatca gggctctgga gtccccagcc gcttctctgg
      301 atccaaagat gcttcggcca atgcagggat tttgctcatc tctgggctcc agtctgagga
      361 tgaggctgac tattactgta tgatttggca caacaatgct tatgtgttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002957             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:17366:5833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002957
VERSION     KCWK01002957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:17366:5833"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68695.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          144 c          132 g           95 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gaattgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc aacagaagcc accgcagggc cctctattgg
      241 tcatctttgc tgatagtaga cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002958             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:20844:13733
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002958
VERSION     KCWK01002958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20844:13733"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68696.1"
                     /translation="VYYCQVWDSSSEWVF"
     J_segment       390..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          145 c          136 g           93 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc agtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc aacagaaggc agcacaggcc cctatgctgg
      241 tcatctttgc tgatagcaaa cggccctcag ggatccctga ccgattctct ggctccaact
      301 cagggaacac cggcaccctg accatcagcg gggtcgaggc cggggatgag gctgtctatt
      361 actgtcaggt gtgggacagt agtagtgagt gggttttcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002959             440 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:9328:14007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002959
VERSION     KCWK01002959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:9328:14007"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    57..402
                     /note="immunoglobulin light chain variable region"
     V_region        57..402
     V_segment       57..363
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>374
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68697.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       365..402
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        403..>440
                     /gene="IGLC"
BASE COUNT           88 a          147 c          106 g           99 t
ORIGIN      
        1 acatggggac tcctctcctc ctcctgctcc tctctcactg cacaggttcc ctctcccagc
       61 ctgtactgac tcagccaccc tccctgtctg catccccggg agcatcggcc agactcccct
      121 gcaccctgag cagtgacctc agtgttggaa gtaaaaacat gtactggtac cagcagaagc
      181 cagggagcgc tcccaggtta ttcctgtact actactccga ctcagacaag caactgggac
      241 ctggggtccc caatcgagtc tctggctcca aggagacctc aagtaacaca gcgtttttgc
      301 tcatctctgg gctccagcct gaggacgagg ccgattatta ctgtcagatg tatgacagta
      361 gtgatgtgtt attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      421 cctcggtcac tctcttcccg
//
LOCUS       KCWK01002960             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:6776:14955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002960
VERSION     KCWK01002960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6776:14955"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..425
                     /note="immunoglobulin light chain variable region"
     V_region        105..425
     V_segment       105..392
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68698.1"
                     /translation="DYYCQVWDSSSRYILF"
     J_segment       399..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>467
                     /gene="IGLC"
BASE COUNT           94 a          140 c          132 g          101 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctct gacctgactc
      121 agccaccctc agtgtcagcg gcctcaggac agacggccag gatcacctgt gggggtgaca
      181 acattggaag taataatgta cactggtacc agcagaagcc agcgcaggcc cctatgttgg
      241 tcatctatgg tggtagtaaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtagat acattttgtt cggaagaggc accaggctga
      421 ccgtcatcgg tcaccccaag gcttctccct tggtcactct gtttccg
//
LOCUS       KCWK01002961             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20504:15002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002961
VERSION     KCWK01002961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20504:15002"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..295
                     /note="immunoglobulin light chain variable region"
     V_region        8..295
     V_segment       8..258
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <220..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68699.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       259..295
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        296..>333
                     /gene="IGLC"
BASE COUNT           64 a          103 c           87 g           79 t
ORIGIN      
        1 acatggggga agagtgtctc catctcctgt tctggaagca gctccaacat cggaagtcat
       61 agtgtctcct ggtaccagca gctcccagga acagctccca aactcctcat ctattatagt
      121 gatcaacgag cctcaggtgt ctctgaccga ttctctggct ctcagtctgg cacgtcagcc
      181 tccctggcca tcagtgggct ccaggccgag gatgaggctg attattactg cgcagcatgg
      241 gatgatagtc tgagcggtta catcttcggt gctgggaccc ggctcgccgt cctaggtcag
      301 cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002962             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:18862:6435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002962
VERSION     KCWK01002962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18862:6435"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..448
                     /note="immunoglobulin light chain variable region"
     V_region        112..448
     V_segment       112..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68700.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       411..448
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           95 a          157 c          122 g          112 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc tccttctcac tctgctggtt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagc atctggggcc cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacatcgg ggcgggttat tatgtatcct ggtaccagca gttcccagga
      241 acagccccca aactcctcat ctatgaaaat aataaacgac cctcaggggt ttctgaccga
      301 ttctctggct ccaagtctgg tacctcagcc tccctgacca tcactggact ccaatctgag
      361 gatgaggctg attattactg ctcagcatgg gatagcagcc tgagtatcaa ttacatcttc
      421 ggttctggga cccgtctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      481 ttcccg
//
LOCUS       KCWK01002963             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:19680:17099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002963
VERSION     KCWK01002963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:19680:17099"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68701.1"
                     /translation="DYYCAIWHSSAIWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          158 c          116 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagttgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tttactacta ctcagactca agtaatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcctcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc tatttgggta ttcggcggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002964             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:5967:3368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002964
VERSION     KCWK01002964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:5967:3368"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..444
                     /note="immunoglobulin light chain variable region"
     V_region        108..444
     V_segment       108..401
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68702.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       407..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          156 c          121 g          110 t
ORIGIN      
        1 acatggggct tcagctgtgg gcacaggagg cagcactcag gacagtctcc agcatggcct
       61 ggtctctcct tctcactctg ctggttcact gcacagggtc ctgggcccag tctgtgctga
      121 cgcagccgcc ctcagcatct ggggcccccg ggcagagggt caccatctcc tgcactggga
      181 gcagctccaa catcggggcg ggttattatg tatcctggta ccagcagttc ccaggaacag
      241 cccccaaact cctcatctat gaaaataata aacgaccctc aggggtttct gaccgattct
      301 ctggctccaa gtctggtacc tcagcctccc tgaccatcac tggactccaa tctgaggatg
      361 aggctgatta ttactgctca gcatgggata gcagcctgag tatcaattac atcttcggtt
      421 ctgggacccg tctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01002965             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:12132:11482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002965
VERSION     KCWK01002965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12132:11482"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68703.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       391..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           98 a          142 c          132 g           92 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gagctgactc
      121 aggcaccctc agtgtcagcg gcctcaggac agacggccag gatcacctgt ggcggagaca
      181 acattggaat taaaaatgtc cactggtacc agcagaagcc agcacaggcc cctgtggtag
      241 tcatctatgc tgataacaaa cggccctcag ggatccctga gcgactctct ggctccaact
      301 cagggaatat tgccaccctg accatcagca gggtcgaggc cggggatgag gcagactatt
      361 actgtcaggt gtgggacagt agtagtaaat gggtattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002966             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:7300:10428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002966
VERSION     KCWK01002966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:7300:10428"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68704.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          163 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccatgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002967             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:7801:6983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002967
VERSION     KCWK01002967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7801:6983"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..295
                     /note="immunoglobulin light chain variable region"
     V_region        7..295
     V_segment       7..251
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <223..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68705.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       265..295
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        296..>333
                     /gene="IGLC"
BASE COUNT           69 a          103 c           83 g           78 t
ORIGIN      
        1 acatggggac agtcggtcac catctcctgc actggaacca gcagtgatgt tgggtattat
       61 catgctgtgt cttggtacca gcatcatcca ggcaaagccc ccaaactcat gatttatgag
      121 gtcaataaac ggcccgcagg ggtctctgat cgcttctctg gctccaagtc tggcaacacg
      181 gcctccctga ccatctctgg gctccagact gaggatgagg ctgattatta ctgcagctca
      241 tatgcaggca gcaacgcttt attcttcgga cgagggaccc gcctgaccgt cctaggtcag
      301 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01002968             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:12061:18540
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002968
VERSION     KCWK01002968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12061:18540"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68706.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          155 c          119 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cgatatattc
      241 tgagatacaa ttcggactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacgcaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caacgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002969             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:2269:13492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002969
VERSION     KCWK01002969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:2269:13492"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68707.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          158 c          127 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtggtg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcactctg agtagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgtt ctaccagtcc gactcagaca agcagctggg accgggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgcaaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002970             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:18368:6944
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002970
VERSION     KCWK01002970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18368:6944"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..264
                     /note="immunoglobulin light chain variable region"
     V_region        7..264
     V_segment       7..227
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68708.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       228..264
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>302
                     /gene="IGLC"
BASE COUNT           60 a           95 c           78 g           69 t
ORIGIN      
        1 acatgggcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcaa gtcccaggaa
       61 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      121 tctctggctc tcagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      181 atgaggctga ttattactgc gcagcatggg atgatagcct gaggggttac atcttcggtg
      241 ctgggacccg gctcgccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      301 cg
//
LOCUS       KCWK01002971             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:18476:8721
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002971
VERSION     KCWK01002971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18476:8721"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..393
                     /note="immunoglobulin light chain variable region"
     V_region        99..393
     V_segment       99..356
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <324..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68709.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       357..393
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>431
                     /gene="IGLC"
BASE COUNT           79 a          144 c          106 g          102 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg attcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc aaggagacct caactaacac agcgtttttg ctcatctctg
      301 ggctccagcc tgaggacgag gccgattatt actgtcaggt gtttgacagt agtgctgtgt
      361 tgttcggagg agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      421 ctctcttccc g
//
LOCUS       KCWK01002972             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:12323:8248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002972
VERSION     KCWK01002972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12323:8248"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68710.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          159 c          114 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt actgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcgtattc tggtaccagc agaagccagg gagtcctccc cggttgcttc
      241 tgtactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctggggtc cagtctgagg
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggtt caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01002973             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:22433:8840
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002973
VERSION     KCWK01002973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:22433:8840"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..446
                     /note="immunoglobulin light chain variable region"
     V_region        101..446
     V_segment       101..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68711.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       413..446
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           91 a          162 c          121 g          110 t
ORIGIN      
        1 acatgggggg gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagcagtga
      181 cctcaatatt ggcaataaaa acatgtactg gtaccagcag aagccaggga gcgctcccaa
      241 gttattcctg tactactact ccgactcaga catgcagctg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtca tacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt attactgtca ggtgtatgac agtagtgctg tattattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01002974             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:19924:6453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002974
VERSION     KCWK01002974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19924:6453"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68712.1"
                     /translation="DYYCASWDDNLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          157 c          118 g          110 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcacc tccaacatcg gaagcaataa tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctctttt attataatga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctcttgctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg catcatggga tgataacctg agcggctaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01002975             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:17441:13380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002975
VERSION     KCWK01002975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17441:13380"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68713.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          140 c          139 g           97 t
ORIGIN      
        1 acatggggcc tgactttggg aagcagcctt ggcggtgcct cagccatggc cgggaccctt
       61 ctcctcctcg gcctccttgc tcactttaca ggctctgcgg cctcctatga ggtgactcag
      121 ccacgctcag tgtccgtgtc ccccggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta aaagtgtgca gtggtaccag cagacgccac cgcaggcccc tgtactggtc
      241 atttatggtg atagggaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggatagtag tagtaaatat gtattattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002976             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:20174:9562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002976
VERSION     KCWK01002976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20174:9562"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68714.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       414..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          164 c          119 g          113 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atttactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgcg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gttttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01002977             332 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:16672:14456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002977
VERSION     KCWK01002977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 332)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16672:14456"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..294
                     /note="immunoglobulin light chain variable region"
     V_region        8..294
     V_segment       8..258
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>266
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68715.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       262..294
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>332
                     /gene="IGLC"
BASE COUNT           72 a           96 c          101 g           63 t
ORIGIN      
        1 acatgggggc ctcaggacag ccggccagga tcacctgtgg gggagacgac attggaacta
       61 aaactgtgca ctggtaccaa cagaagccac cgcagggccc tctattggtc atctttgctg
      121 atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca gggaacaccg
      181 ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac tgtcaggtgt
      241 gggacagtag tagtaaatgg atattcggcg gggggacccg gctaagcgtc ctaggtcagc
      301 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002978             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:23517:6994
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002978
VERSION     KCWK01002978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23517:6994"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..265
                     /note="immunoglobulin light chain variable region"
     V_region        1..265
     V_segment       1..228
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68716.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       229..265
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           64 a           91 c           86 g           62 t
ORIGIN      
        1 acatgggggg gagacaacat tggaagtaag agtgtgcact ggtaccagca caagccaccg
       61 caggccccta tcctggtcat ctattattat accgaacggc cctcggcgat ccctgagcga
      121 ttctctggct ccaaatcagg gaacaccgcc accctgacca tcagcggggt cgaggccggg
      181 gatgaggctg actattactg tcaggtgtgg gacactacta ttgatcatgg ctttttcgga
      241 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      301 ccg
//
LOCUS       KCWK01002979             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:7557:15704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002979
VERSION     KCWK01002979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7557:15704"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68717.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       391..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           89 a          139 c          136 g           98 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcaggca
      121 ccctcgattt cagtgtcccc cggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtgaag ttgtgaactg gtaccagcag aagccaccgc aggcccctgt gttggtcatg
      241 tatgctgata gcgagcggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacacggcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acatgaatag tcatcatcta ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002980             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:22881:17096
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002980
VERSION     KCWK01002980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22881:17096"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68718.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           95 a          143 c          131 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca gactctgcga cctcctatga actgagtcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccag cagaagccac cgcagggccc tatattggtc
      241 atctttgctg atagtaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01002981             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:18018:21732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002981
VERSION     KCWK01002981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18018:21732"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68719.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          158 c          121 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat gttgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg ctcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacgct ttattcttcg gacgagggac
      421 ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002982             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:5862:9474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002982
VERSION     KCWK01002982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:5862:9474"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68720.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          159 c          113 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcaa cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002983             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:8701:4032
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002983
VERSION     KCWK01002983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8701:4032"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68721.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          158 c          120 g          101 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgtctctg cctccctggg agcctcggtc aaactcacct gtactttgaa cagtgggcac
      181 agcagctaca ccatcgcatg gcatcagcag cagcaaggga aggccccccg gtacttgatg
      241 tggcttaaaa gtgaaggcag ccatagcaag ggggacggga tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatactgac attgtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002984             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:22094:20209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002984
VERSION     KCWK01002984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22094:20209"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68722.1"
                     /translation="DYYCQVWDISTDHPVLF"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          142 c          133 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagc ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccagggtc acctgtggag gagagaacct
      181 tggatatgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctaaccga ttctctggct ccaaatcagg
      301 gaatacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacattagta ctgaccatcc ggtattattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002985             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:7242:10656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002985
VERSION     KCWK01002985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7242:10656"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..431
                     /note="immunoglobulin light chain variable region"
     V_region        110..431
     V_segment       110..395
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68723.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       396..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           98 a          145 c          133 g           93 t
ORIGIN      
        1 acatgggggc cctgtctggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggcc tcctcgctta ctgcacaggc tctgcgacct cctatgagct
      121 gactcaggca ccctcagtgt cagcggcctc aggacagacg gccaggatca cctgtggcgg
      181 agacaacatt ggaattaaaa atgtccactg gtaccagcag aagccagcac aggcccctgt
      241 ggtagtcatc tatgctgata acaaacggcc ctcagggatc cctgagcgac tctctggctc
      301 caactcaggg aatattgcca ccctgaccat cagcagggtc gaggccgggg atgaggcaga
      361 ctattactgt caggtgtggg acagtagtag taaatgggta ttcggcggag ggacccggct
      421 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01002986             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:8209:15554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002986
VERSION     KCWK01002986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8209:15554"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..398
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68724.1"
                     /translation="DYYCASYEGSNTFLF"
     J_segment       402..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           89 a          158 c          118 g          105 t
ORIGIN      
        1 acatggggga tctcaggagg cagcgctctc aggacttctc caccatggtc tgggctctgc
       61 tcctcctcac cctcctcact cagggcacag gatcctgggc tcaggctgcc ccgactcagc
      121 ctccctctgt gtccgggtct cctggacagt cggtcaccat ctcctgcagt ggaaccagca
      181 ctaagattgg gtatcacaat gctgtgtcct ggtaccaaga gcatccaggc aaagccccca
      241 aactcatgat ttatgacgtc aataagcggc ccacagggat ctctgatcgc ttctctggct
      301 ccaagtctgg cgacacggcc tccctgacca tctctgggct ccaggctgat gatgaggctg
      361 attattactg cgcctcatat gaaggcagca atactttcct cttcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002987             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:7975:16009
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002987
VERSION     KCWK01002987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7975:16009"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68725.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           92 a          143 c          133 g           96 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca cagtctctgc gacctcctat gaactgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaat taaaactgtg cactggtacc agcagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgatagtaaa cggccctcgg ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01002988             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:25117:17764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002988
VERSION     KCWK01002988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:25117:17764"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68726.1"
                     /translation="DYYCQVWGMTRDHPVF"
     J_segment       388..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           87 a          142 c          139 g           92 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggagagac ggccaggatc acctgtgggg gagaccacat
      181 tggaagtgag gttgtgaact ggtaccaaca gaagccaccg caggcccctg tggtggtcta
      241 tcctaatagc gaacggccct cagggatccc tgagcgattc tctggctcca aatcagggaa
      301 cacggccacc ctgaccatca gcggggtcga ggccggggat gaggctgact attactgtca
      361 ggtgtggggc atgactaggg atcatccggt attcggcgga gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01002989             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:12596:4028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002989
VERSION     KCWK01002989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12596:4028"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..407
                     /note="immunoglobulin light chain variable region"
     V_region        87..407
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68727.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       372..407
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>446
                     /gene="IGLC"
BASE COUNT           93 a          140 c          116 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aagatcacct gctctggaga tgcactgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcgat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gcagtggtta tggcttattc ggaggaggga cccggctgac cgtcctacgt cagcccaagg
      421 ctgccccctc ggtcactctc ttccag
//
LOCUS       KCWK01002990             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:22569:14271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002990
VERSION     KCWK01002990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:22569:14271"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68728.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          163 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgcg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01002991             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:20656:10718
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002991
VERSION     KCWK01002991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20656:10718"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68729.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          160 c          120 g          107 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc gtcaatgtgg
      181 gtagttacag cgtattctgg taccagcaga agccagggag tcctccccgg taccttctgt
      241 actaccagtc agactcaagg aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggctgt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc ctatggcaca gcagcgcttc ttgcatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002992             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:12630:11567
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002992
VERSION     KCWK01002992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12630:11567"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..407
                     /note="immunoglobulin light chain variable region"
     V_region        91..407
     V_segment       91..377
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68730.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       378..407
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>447
                     /gene="IGLC"
BASE COUNT           87 a          139 c          123 g           98 t
ORIGIN      
        1 acatggggag cagagctctg gggtgtctcc accatggcct ggactcctct ctggctcacc
       61 ctcctcagtc tttgcacagg ttctatggtt tcttctgagc tgactcagga ccctgcagtg
      121 tctgtggcct tgggacagac agtcaggatt acctgccaag gagacagcct cagaagctct
      181 tatgcaagct ggtaccaaca gaggccaggc caggcccctg tgctggtcgt ctatggtaac
      241 aactaccggc cctcagggat cccagagcga ttctctggct cctactcacg aaacacagct
      301 tccttgacca tctctggggc tcaggtggaa gatgaggctg actattactg tgactcctgg
      361 gacagcagcg gaacccaatt cggaggaggg acccggctga ccgtcctggg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01002993             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:11341:9752
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002993
VERSION     KCWK01002993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:11341:9752"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68731.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       408..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           89 a          165 c          113 g          113 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcaccaat
      181 gttggtagtt acagcatttt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
      241 ctctactact actcagactc aactaagcac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc caatgcaggg cttttactga tctctgggct ccagtctgag
      361 gatgaggctg actattactg tgccatttgg cacagcagcg cttcttgcat cttcggtcct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01002994             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:17437:12899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002994
VERSION     KCWK01002994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17437:12899"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68732.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          161 c          122 g          105 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa caacatccag acacagcccc
      241 caaactcgtg atttatgagg tcaatcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct gacaacacgg cctccctgac catctctggc ctccagcctg aggacgaggc
      361 tgattattac tgcagctcat atgcaggcag cgacactttc gtgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01002995             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:6821:9156
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002995
VERSION     KCWK01002995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6821:9156"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..436
                     /note="immunoglobulin light chain variable region"
     V_region        90..436
     V_segment       90..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68733.1"
                     /translation="DYYCSIGHSSGLYIF"
     J_segment       401..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           89 a          158 c          116 g          113 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt caccggtggc atcaatgttg
      181 ctgtctacca catacactgg taccagcaga agccagggag tcccccccgg tttcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccagtaatgc ttcagcgaac acagggattt tacgcatttc tgggctccag tctgaggatg
      361 aggctgacta ttactgttcc attggacaca gcagcggtct ttacatcttc ggtgctggga
      421 cccggctcac cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01002996             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:17250:11480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002996
VERSION     KCWK01002996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17250:11480"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..401
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68734.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       404..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           88 a          157 c          129 g          102 t
ORIGIN      
        1 acatgggggg ctgtggctca ggaagcagag cctggagcgt ctccaccatg gcctgggctc
       61 cactcctcct caccctcctc gctcactgca cagggtcttg ggctgaggtt ctgttcacgc
      121 agccccattc tgtgtcgggg tctccggggc agacggtcac catctcctgt acccgcagca
      181 gaggcaacat tgacaatagt tatgtgcagt ggtaccagca gcgcccgggc agtgccccga
      241 ccacagtgat ttacagagat aaccaaagag cctctggggt ccctgatcgg ttctctggct
      301 ccatcgacag ctcctccaac tctgcctccc tcaccatctc tgggctgaag tctgaggacg
      361 aggctgacta ctactgtcag tctactgatg gcaactacaa tcggttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01002997             348 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:13081:2943
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002997
VERSION     KCWK01002997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 348)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13081:2943"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..310
                     /note="immunoglobulin light chain variable region"
     V_region        95..310
     V_segment       95..273
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <238..>282
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68735.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       274..310
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        311..>348
                     /gene="IGLC"
BASE COUNT           63 a          112 c           88 g           85 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca ggttatttct gtactacaac
      121 tccgactcag acaagcagct gggacctggg gtccccaatc gagtctctgg ctccaaggag
      181 acctcaagta acacagcgtt tttgctcatc tctgggctcc agcctgagga cgaggccgat
      241 tattactgtc aggtatatga cagtagtgct aatgtgttat tcggaggagg gacccggctg
      301 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01002998             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:25913:14554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002998
VERSION     KCWK01002998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25913:14554"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68736.1"
                     /translation="DYYCQSTDTSGNYIF"
     J_segment       389..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          104 a          132 c          124 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctggg gcctcctttg agctgacaca
      121 ggcaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggaggaat
      181 actggcaaaa aaatatgctc agtggttgca gcagaagcca ggccaggccc ctgtgttggt
      241 aatatataaa gacagtgaga ggccctcagg gatccctgaa cgattctcta gttccagttc
      301 agggacaaca gttgccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca acagacacca gtggtaatta catcttcggt gctgggaccc ggctcaacgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01002999             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:16223:18209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01002999
VERSION     KCWK01002999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16223:18209"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..438
                     /note="immunoglobulin light chain variable region"
     V_region        91..438
     V_segment       91..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68737.1"
                     /translation="DYYCAIGHSSGNYIF"
     J_segment       405..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          155 c          119 g          112 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctatgct gactcagccg gcctccttct
      121 cagcatctcc tggagcttca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catacactgg taccagcaga agccagggag tcctccccgg tttcttctga
      241 gatacaagtc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaggatgc ttcagcgaac acaggaattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtaa ttatatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003000             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:6471:9725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003000
VERSION     KCWK01003000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:6471:9725"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68738.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       394..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           87 a          141 c          136 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccggaccct
       61 tctcctcctc ggcctccttg ctcactttac aggctctgtg gcctcctatg agttgcctca
      121 gccacgctca gtgtccgtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt aatagtgtgc attggtacca gcagaagcca ccgcgggccc ctgtattggt
      241 catctctgtt gatagcgaac ggccctcagg gatccctgag cgattctctg gttccagatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggataata tttataaata cgcggtattc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003001             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:21757:10271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003001
VERSION     KCWK01003001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21757:10271"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..448
                     /note="immunoglobulin light chain variable region"
     V_region        119..448
     V_segment       119..412
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68739.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       417..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>487
                     /gene="IGLC"
BASE COUNT           97 a          161 c          120 g          109 t
ORIGIN      
        1 acatggggag cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gttccagggt cctgggccca
      121 gtctgtgctg actcagccac cctcagcgtc tgggactccc gggcagagtg tcaccatctc
      181 gtgctctgga agcagctcca acattggaac taattatgta tactggtacc aacacctccc
      241 aggaacggcc cccaaactcc tcatctatta tagtaatcag cgaccctcag gggtccctga
      301 ccgattctct ggctctaagt ctggcacctc agcctccctg gccatcactg gtctccgatc
      361 tgaggatgag gctgattatt actgtgcagc atgggataac agcctgacca gtccggtatt
      421 cggaggaggg acccggctga ccgtcctaag tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01003002             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:12305:14549
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003002
VERSION     KCWK01003002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12305:14549"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..332
                     /note="immunoglobulin light chain variable region"
     V_region        8..332
     V_segment       8..295
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <257..>304
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68740.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       296..332
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        333..>370
                     /gene="IGLC"
BASE COUNT           74 a          117 c           96 g           83 t
ORIGIN      
        1 acatggggtg ctgactcagc ctccctcagc gtctgaggcc gccaggaaca gtgtcgccat
       61 ctcctgttct ggaagcagct ccaacatcgg aagtcatagt gtatcctggt accagcagct
      121 cccaggaaca gctcccaaac tcctcatcta ttatgatgat caacgagcct caggtgtctc
      181 tgaccgattc tctggctcca ggtctggcac gtcagcctcc ctggccatca gtgggctcca
      241 gaccgaggat gaggctgatt attactgcgc agcatgggat gatagcctga gaggttacat
      301 cttcggtgat gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac
      361 tctgttcccg
//
LOCUS       KCWK01003003             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18383:20101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003003
VERSION     KCWK01003003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18383:20101"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68741.1"
                     /translation="DYYCALWYNSAWIF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          158 c          114 g          113 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctgt cacagcctgt gctgactcag ccggcctccc
      121 tctcagtctc tcctggaaca tcagtcagac tcacctgcac cttgcgcact ggcatcaatg
      181 ttggtggctc ctacatattc tggtaccaac agaagacagg gcgtcctccc cggtaccttc
      241 tgaactacta ctcagactca aataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcaggac ttttactgat ctctggcctc cagtctgagg
      361 atgaggctga ctattactgt gccttatggt acaacagcgc ttggatattc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003004             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:11393:21860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003004
VERSION     KCWK01003004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11393:21860"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68742.1"
                     /translation="DYYCALWYNSAWIF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          157 c          114 g          113 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctgt cacagcctgt gctgactcag ccggcctccc
      121 tctcagtatc tcctggaaca tcagtcagac tcacctgcac cttgcgcact ggcatcaatg
      181 ttggtggctc ctacatattc tggtaccaac agaagccagg gcgtcctccc cggtaccttc
      241 tgaactacta ctcagactca aataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcaggac ttttactgat ctctgggctc caatctgagg
      361 atgaggctga ctattactgt gccttatggt acaacagcgc ttggatattc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003005             376 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:12339:20446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003005
VERSION     KCWK01003005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 376)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12339:20446"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..338
                     /note="immunoglobulin light chain variable region"
     V_region        14..338
     V_segment       14..295
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <263..>310
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68743.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       304..338
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        339..>376
                     /gene="IGLC"
BASE COUNT           74 a          116 c          114 g           72 t
ORIGIN      
        1 acatggggcg acctcctatg agctggctca gccaccctcg gtgtcagcgg cctcaggaca
       61 gacggccagg atcacctgtg ggggagacaa cattggaagt aactatgtgc actggtacca
      121 gcagaagcca gcgcaggccc ctgtcgagat catctttgct gataacaaac ggccctcagg
      181 gatccctgag cgattctctg gctccaactc agggatcacc gccaccctga ccatcagcgg
      241 ggtcgaggcc ggggatgagg ctgactattt ctgtcaggtg tggggcagtc gtagtgatca
      301 tccggtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      361 ggtcactctc ttcccg
//
LOCUS       KCWK01003006             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:3026:8354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003006
VERSION     KCWK01003006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:3026:8354"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68744.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           90 a          149 c          127 g          114 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcagtat ttcttgcact
      181 gggagcagct ccaacattgg aggttattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccaaac tcctcatcta tgaaaatgat aaacgaccct cagggatttc tgatcgattc
      301 tctggctccc agtctgattc ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagcttga gtgttgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003007             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16210:9472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003007
VERSION     KCWK01003007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16210:9472"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68745.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          157 c          120 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctt actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003008             339 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:22810:10904
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003008
VERSION     KCWK01003008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 339)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:22810:10904"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    173..301
                     /note="immunoglobulin light chain variable region"
     V_region        173..301
     V_segment       173..264
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <226..>273
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68746.1"
                     /translation="DYYCQVWGSRSDHPVF"
     J_segment       267..301
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        302..>339
                     /gene="IGLC"
BASE COUNT           55 a          114 c          105 g           65 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gtctctgcga cctcctatga actgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccaggg tcacctgtgg ggcagggaac
      181 accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta ttactgtcag
      241 gtgtggggca gtcgtagtga tcatccggta ttcggcggag ggacccggct gaccgtccta
      301 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003009             340 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:15186:6075
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003009
VERSION     KCWK01003009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 340)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15186:6075"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..302
                     /note="immunoglobulin light chain variable region"
     V_region        7..302
     V_segment       7..264
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <227..>274
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68747.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       266..302
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        303..>340
                     /gene="IGLC"
BASE COUNT           74 a          103 c           97 g           66 t
ORIGIN      
        1 acatgggtca gtgtccccag gacagacggc caggatcacc tgtgggggag acaacattgg
       61 aagtcaaagt gtgcactggt accagcacaa gccaccgcag gcccctgttc tggtcatctt
      121 ttattatacc gaacggccct caggaatccc tgagcgaatc tctggctcca aatcagggaa
      181 caccgccacc ctgaccatca gcggggtcga ggccggggat gaggctgact attactgtca
      241 ggtgtgggac acaagtcttg atcacggctt attcggagga gggacccggc tgaccgtcct
      301 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003010             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:12496:15635
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003010
VERSION     KCWK01003010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12496:15635"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68748.1"
                     /translation="DYYCQVWDSSTRYAVF"
     J_segment       399..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          147 c          137 g           95 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc attgccagcg gcctcaggac agacggccag gatcgcctgt gggggagaca
      181 gcattggaag tgaaaatgtg ttctggtacc agcagaagcc acggcaggcc cctgtcctgg
      241 tcatctatgg tgatacgaaa cggccctcag ggatccctga gcgattctct ggctccatct
      301 ctgggaacac cgccaccctg accatcaaca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtactagat acgcggtttt cggcggaggg acccggctaa
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003011             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:18811:15713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003011
VERSION     KCWK01003011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18811:15713"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68749.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           89 a          155 c          120 g          109 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgccgg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003012             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:14869:18128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003012
VERSION     KCWK01003012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14869:18128"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..294
                     /note="immunoglobulin light chain variable region"
     V_region        8..294
     V_segment       8..260
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68750.1"
                     /translation="DYYCCSRSSSSTYVF"
     J_segment       261..294
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>334
                     /gene="IGLC"
BASE COUNT           63 a          108 c           82 g           81 t
ORIGIN      
        1 acatggggga cagtcggtca ccatctcctg cactggaacc agcagtgacg ttggtggtta
       61 taactctgtc tcctggtacc aacaacaccc aggcaaagcc cccaaagtca tgatttttgg
      121 tgtcaataat cggccctctg gggtctctga ccgcttctct ggctccaagt ctggcaacac
      181 ggcctccctg accatctctg ggctccagtc tgaggacgag gctgattatt actgttgttc
      241 acgttcaagc agcagcactt acgtcttcgg tcctgggacc cggctcaccg tcctgggtca
      301 gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01003013             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:23301:14759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003013
VERSION     KCWK01003013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:23301:14759"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68751.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       392..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          148 c          136 g           93 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag gctctgcgac ctcctatgag ctgactcagc
      121 caccctcggt gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa atatgtgcac tggtaccagc agaagccagc gcaggcccct gtgttggtca
      241 tctatgctga taccagacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcggtg tcgaggccgg gtatgaggct gactatttct
      361 gtcaggtgtg ggacgatagt agtgatcatc cggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003014             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:25138:15340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003014
VERSION     KCWK01003014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25138:15340"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..279
                     /note="immunoglobulin light chain variable region"
     V_region        8..279
     V_segment       8..235
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68752.1"
                     /translation="DYYCSTYVGSNTYMF"
     J_segment       242..279
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>317
                     /gene="IGLC"
BASE COUNT           66 a           99 c           80 g           72 t
ORIGIN      
        1 acatgggctc ctgcactgga accagcagtg atattgcgta tgataatgct gtgtcttggt
       61 accagcagca tccaggcaag gcccccaaac tcatgattta tgacgtcagt aagcggccct
      121 caggggtctc tgatcgcttc tcgggctcca agtctggcaa cacggcctcc ctgaccatct
      181 ctgggctcca ggctgaggat gaggctgact attactgcag cacatatgta ggcagcaaca
      241 cttacatgtt cgatcctggg acccggctca ccgtcctagg tcagcccaag gcttccccca
      301 cggtcactct gttcccg
//
LOCUS       KCWK01003015             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16056:14893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003015
VERSION     KCWK01003015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16056:14893"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..453
                     /note="immunoglobulin light chain variable region"
     V_region        123..453
     V_segment       123..416
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68753.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       417..453
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           92 a          158 c          124 g          117 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactt cacagttcca gggtcctggg
      121 cccagtctgt gctgacgcag ccgccctcag tgtctggggc gcccgggcag agggtcacca
      181 tctcctgcac tgggagcagc tccaacattg gagattattt tgtgcagtgg taccagcacc
      241 ttccaggaac ggcccccaaa ctcctcatct atgaaaataa taagcgaccc tcaggcattt
      301 ctgatcgatt ctctggttcc cagtctggaa cctcagcctc cctgaccatc actggactcc
      361 agtctgagga tgaggctgat tattactgcc agtcctatga cagcagtttg attgctgtgt
      421 tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      481 ctctcttccc g
//
LOCUS       KCWK01003016             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:9167:5202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003016
VERSION     KCWK01003016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9167:5202"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68754.1"
                     /translation="DYHCQVWDINSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          144 c          132 g          101 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gtctctgcgg cctcctatga tctgactcag
      121 ccaccctcga tttcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtgaa ctggtaccaa cagaagccac cgctggcccc tgtgttggtc
      241 atctatgctg atagcgaccg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaccacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactatcac
      361 tgtcaggtgt gggacattaa tagtcatcat ctgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003017             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:11689:9284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003017
VERSION     KCWK01003017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11689:9284"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..394
                     /note="immunoglobulin light chain variable region"
     V_region        76..394
     V_segment       76..362
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68755.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       363..394
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>432
                     /gene="IGLC"
BASE COUNT           84 a          136 c          116 g           96 t
ORIGIN      
        1 acatggggtg tctccaccat ggcctggact cctctctggc tcaccctcct cagtctttgc
       61 acaggttcta tggtttcttc tgagctgact caggaccctg cagtgtctgt ggccttggga
      121 cagacagtca ggattacctg ccaaggagac agcctcagaa gctcttatgc aagctggtac
      181 caacagaggc caggccaggc ccctgtgctg gtcgtctatg gtaacaacta ccggccctca
      241 gggatcccag agcgattctc tggctcctac tcacgaaaca cagcttcctt gaccatctct
      301 ggggctcagg tggaaggtga ggctgactat tactgtgact cctgggacag cagcggaacc
      361 caattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      421 actctcttcc cg
//
LOCUS       KCWK01003018             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:10242:8456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003018
VERSION     KCWK01003018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10242:8456"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..434
                     /note="immunoglobulin light chain variable region"
     V_region        86..434
     V_segment       86..397
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68756.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       400..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          161 c          111 g          110 t
ORIGIN      
        1 acatgggggg aaagaggctg tgtccaccat ggcctggact cctctcctcc tcctgctcct
       61 ctctcactgc acaggttccc tctcccagcc tgtgctgacc cagccaacct ccctctcagc
      121 atctccggga gcatcagcca gactcagctg caccttgagc agtggcacca atgttggtag
      181 ttacaggata ttctggtacc agcagaagcc agggagtcct ccccggtacc ttctgtacta
      241 ctactcagac tcaactaagc accagggctc tggagtcccc agccgcttct ctggatccaa
      301 agatgcttca gccaatgcag ggcttttact gatctctggg ctccagtctg aagatgaggc
      361 tgactattac tgtgccatat ggcacagcag cgcttcttgc atcttcggtc ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01003019             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:20335:19225
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003019
VERSION     KCWK01003019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20335:19225"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68757.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          138 c          134 g          103 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggaaagacg gccaggatca cctgtggggg agacaatatt
      181 ggaagtgaag ttgtcaactg gtaccagcag aagccaccgc aggcccctgt ggtggtcatc
      241 tatgctgatt atgaacggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacacggcca ccctgaccat cagcggagtc gaggccgggg atgaggctga ctattactgt
      361 caggtttggg acatttatat tgatcatccg gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003020             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:14638:7499
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003020
VERSION     KCWK01003020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14638:7499"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68758.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          141 c          135 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccaaca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat cactgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgcggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ctgatcatcc ggtgttgttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003021             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:18870:13132
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003021
VERSION     KCWK01003021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18870:13132"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..395
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68759.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       397..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           90 a          157 c          122 g          101 t
ORIGIN      
        1 acatgggggg ggcacaggag gcagcactca ggacagtctc cagcatggcc tcgtctcctc
       61 tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg ctgacacagc
      121 cgccctcagt gtctggggcc ccagggcaga gggtcaccat ctcctgcact gggagcagct
      181 ccaacattgg aggttattat atatcctggt accagcagct cccaggaacg gcccccaaac
      241 tcctcgtcta tgacaataat aagcgaccct caggggtttc tgaccgattc tctggctcca
      301 agtctggttc ctcagccacc ctgaccatca ctgggctcca gactgaggat gaggctgatt
      361 attactgcca gtcctatgac agcagtctga gtgctcgggt attcggcgga gggacccggc
      421 taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003022             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:7751:11100
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003022
VERSION     KCWK01003022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7751:11100"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68760.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           91 a          153 c          119 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcata atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaagacgg cctccctgac catctctgga ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacgcttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003023             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:23847:12527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003023
VERSION     KCWK01003023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23847:12527"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..389
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68761.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          155 c          112 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cacctccaac
      181 atcggaagca ataatgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 ttttattata atgatcaacg agcctcaggt gtctctgacc gattctcttg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcatcat gggatgatac cctgagcggc tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003024             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:12038:6304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003024
VERSION     KCWK01003024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12038:6304"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68762.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          157 c          122 g          107 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaataa tgtgtcctgg taccagcacc tcccaggaac
      241 agctcccaaa ctccccatct attataatga tcaacgaggc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcgtggga tgatagcctg agcagttaca tcttcgctgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01003025             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:23663:21077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003025
VERSION     KCWK01003025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23663:21077"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68763.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          164 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg ccctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003026             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:22687:20182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003026
VERSION     KCWK01003026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22687:20182"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..403
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68764.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       409..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          160 c          119 g          108 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtactgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggaa gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaag caactgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aggtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcagatg tatgacagta gtgatgtatt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003027             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:18239:3976
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003027
VERSION     KCWK01003027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18239:3976"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..413
                     /note="immunoglobulin light chain variable region"
     V_region        90..413
     V_segment       90..376
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68765.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       378..413
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>452
                     /gene="IGLC"
BASE COUNT           89 a          145 c          121 g           97 t
ORIGIN      
        1 acatgggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc ctcctcggcc
       61 tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca ccctcggtgt
      121 cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt ggaagtcaaa
      181 gtgtacactg gtaccagcac aagccaccgc aggcccctgt tctgctcatc ttttattata
      241 ccgaacggcc ctcaggaatc cctgagcgat tctctggctc caaatcaggg aacaccgcca
      301 ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt caggtgtggg
      361 acacaactat tgatcacggc ttgttcggag gagggacccg gctgaccgtc ctatgtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003028             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:20694:7807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003028
VERSION     KCWK01003028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20694:7807"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68766.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          138 c          137 g          103 t
ORIGIN      
        1 acatgggggg gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggaaag acggccagga tcacctgtgg gggagacaat
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tattgatcat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003029             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:21198:6702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003029
VERSION     KCWK01003029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21198:6702"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..312
                     /note="immunoglobulin light chain variable region"
     V_region        8..312
     V_segment       8..273
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <240..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68767.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       282..312
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>350
                     /gene="IGLC"
BASE COUNT           74 a          110 c           88 g           78 t
ORIGIN      
        1 acatgggagc gtctggggcc cccggacaga gggtcaccat ctcctgcatg agcagcagct
       61 ccaacatcgg ggcggcatat tatgtatcct ggtaccaaca gttcccagga acagccccca
      121 aagtcctcat ctttgaaaat aataagcgac cctcaggggt ttctgaccga ttctctggct
      181 ccaagtctgg tccctcagcc tccctgacca tcactggact ccaatctgag gatgaggctg
      241 attattactg tttagcatgg gataccagcc tgaattggat cttcggcgga gggacccggc
      301 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003030             326 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:25833:9365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003030
VERSION     KCWK01003030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 326)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:25833:9365"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..288
                     /note="immunoglobulin light chain variable region"
     V_region        8..288
     V_segment       8..251
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <219..>260
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68768.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       255..288
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        289..>326
                     /gene="IGLC"
BASE COUNT           66 a          107 c           81 g           72 t
ORIGIN      
        1 acatgggggt caccatctcc tgcacccgca gcagtggcag cattgacaac ggctttgtgt
       61 actggtacca gcagcggccg ggcagcgctc ccaccactgt gatttacaaa gataaccaaa
      121 gaccctctgg ggtccctgat cggttctctg gctccatcga cagctcctcc aactctgcct
      181 ccctcaccat ctctggactg aaatctgagg acgaggctga ctattactgt cagtcttatg
      241 acagcagcag tgtattattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      301 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003031             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:25942:18637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003031
VERSION     KCWK01003031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:25942:18637"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68769.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       408..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          154 c          119 g          110 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggaacatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catacactgg taccagcaga agccagggag tcctccccga tatcttctga
      241 gatacaaatc ggactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac gcagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtga ttatattttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003032             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:17460:2448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003032
VERSION     KCWK01003032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17460:2448"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68770.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          163 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agtagtgacc
      181 tcagtgttgg tagtaaaaac atctactggt accagctgaa gccagggagc gctcccaggt
      241 cattcctgta ctactactcc gactcagaca agcagcgggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tctatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003033             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:17486:18774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003033
VERSION     KCWK01003033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17486:18774"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68771.1"
                     /translation="DYYCQSADSSANHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          107 a          135 c          124 g          100 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctcagag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagcgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc agtggttcca gcagaagcca ggccaggccc ctgtgttggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgaa cgattctcta gttccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggta gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagca gtgctaatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003034             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:13732:13602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003034
VERSION     KCWK01003034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13732:13602"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..436
                     /note="immunoglobulin light chain variable region"
     V_region        90..436
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68772.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           90 a          157 c          120 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgactacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 gatacagatc agactcagat aagggccagg gctctggagt ccccagccgg ttctctggat
      301 ccaaagatgc tgcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttattgtgcc attgggcaca gcagcggtcc ttacttcttc ggtgctggga
      421 cccggctcac cgtccttggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003035             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:23276:10053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003035
VERSION     KCWK01003035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:23276:10053"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68773.1"
                     /translation="DYYCAAWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          158 c          120 g          112 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtttcct ggtaccaaca cctcccagaa
      241 acgtctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgctgcatgg gatgatagcc tgaccggtta catattcggt
      421 gttgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003036             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:18768:18485
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003036
VERSION     KCWK01003036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18768:18485"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68774.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           90 a          162 c          119 g          110 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt aataaaaaca tgtactggta ccaacagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caactaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtttgacagt agtgctgtgt tattcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01003037             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:15814:9123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003037
VERSION     KCWK01003037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:15814:9123"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68775.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgttg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003038             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:20896:13040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003038
VERSION     KCWK01003038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20896:13040"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..403
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68776.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       405..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           96 a          154 c          115 g          115 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcgcagcctg tgctgactca gccaacctcc
      121 ctctcagcat ctcctggagc atcagccaga ctcacctgca ccttgaacag tggcatcagt
      181 gttggtaatt acaggatatt ctggtaccac cagaagccag ggagtcctcc ccggtatctt
      241 ctgaactacc acacagactc agatattcac cagggctctg gagtccccag ccgcttctct
      301 gggtccaagg atgcttcggc caatgcaggg attttactca tctctggact ccagtctgag
      361 gatgaggctg actattactg tatgatttgg cacaacaatg cttattgggt attcggcgga
      421 gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003039             283 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:11407:11404
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003039
VERSION     KCWK01003039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 283)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:11407:11404"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..245
                     /note="immunoglobulin light chain variable region"
     V_region        8..245
     V_segment       8..206
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>217
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68777.1"
                     /translation="DYHCQVFDSRDVLF"
     J_segment       208..245
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        246..>283
                     /gene="IGLC"
BASE COUNT           56 a           84 c           79 g           64 t
ORIGIN      
        1 acatgggtgg taccagcaga agccagggag cgctcccagg ttattcctgt actactattc
       61 cgactcagac aagcagctgg gacctggggt ccccaatcga gtctctggct ccaaggagac
      121 ctcaagtaac acagcgtttt tgctcatctc tggactccag cctgaggacg aggccgatta
      181 tcactgtcag gtgtttgaca gtcgtgatgt gttgttcgga ggagggaccc ggctgaccgt
      241 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003040             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:7233:18512
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003040
VERSION     KCWK01003040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7233:18512"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68778.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          161 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatattgg caataaaaac atgtactggt accagcagaa gccagggagc gctcccaagt
      241 tattcctgta ctactactcc gactcagaca tgcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01003041             517 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:16485:7773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003041
VERSION     KCWK01003041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 517)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16485:7773"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    149..479
                     /note="immunoglobulin light chain variable region"
     V_region        149..479
     V_segment       149..442
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <404..>451
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68779.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       443..479
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        480..>517
                     /gene="IGLC"
BASE COUNT          104 a          157 c          142 g          114 t
ORIGIN      
        1 acatggggag agtatgaaga gagggagaga tttgggtgaa gcgcagcttc agctgtgggt
       61 acagaaggca ggactcagga caatctccag catggcctgg ttccctctcg tcctcaccct
      121 cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagcctc cctcagcgtc
      181 tgaggccgcc aggaacagtg tcgccatctc ctgttctgga agcagctcca acatcggaag
      241 tcatagtgta tcctggtacc agcagctccc aggaacagct cccaaactcc tcatctatta
      301 tgatgatcaa cgagcctcgg gtgtctctga ccgattctct ggctccaggt ctggcacgtc
      361 agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt actgcgcagc
      421 atgggatgat agcctgagag gttacatctt cggtgatggg acccggctca ccgtcctagg
      481 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01003042             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:8352:6406
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003042
VERSION     KCWK01003042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8352:6406"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..417
                     /note="immunoglobulin light chain variable region"
     V_region        100..417
     V_segment       100..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68780.1"
                     /translation="DYYCYSSDSNSKWLF"
     J_segment       389..417
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>459
                     /gene="IGLC"
BASE COUNT           99 a          141 c          122 g           97 t
ORIGIN      
        1 acatgggggg ggctcaggag gcagagctct gggtgtctca ccatagcctg gattcctctc
       61 ctactcccca tcctcacttt ctgcacaggc tctgcagcct cctatgagat gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccaaaaaaat atacttattg gttcccgcag aaggcaggcc agccccctat ggtgatcatc
      241 tatgaggaca ccaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactct cagtggggcc caggtggagg atgaaggtga ctactactgt
      361 tactcatcag acagcaatag taaatggcta ttcgacggag ggacccggct gaccgtcgta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003043             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:25708:4923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003043
VERSION     KCWK01003043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:25708:4923"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68781.1"
                     /translation="DYYCMIWHNYAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          153 c          112 g          118 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac ttacctgcac cttgaacagt ggcatcagtg
      181 ttgctaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactg cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaactatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003044             279 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:21564:12215
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003044
VERSION     KCWK01003044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 279)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21564:12215"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..241
                     /note="immunoglobulin light chain variable region"
     V_region        8..241
     V_segment       8..202
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <166..>213
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68782.1"
                     /translation="DYYCSAWDSSLTGGFF"
     J_segment       204..241
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        242..>279
                     /gene="IGLC"
BASE COUNT           56 a           86 c           74 g           63 t
ORIGIN      
        1 acatgggatg tatactggta ccagcagttc tcagggaagg cccccaaact cctcatccat
       61 aataataatc agcgaccctc aggggtccct gatcgattct ctggctccaa gtctggcacg
      121 tcagcctccc tggacatcag tgggctccag tccgaggatg aggctgatta ttactgctca
      181 gcatgggata gcagtctgac cggtggcttt ttcggaggag ggacccggct gaccgtccta
      241 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003045             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:13142:5576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003045
VERSION     KCWK01003045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13142:5576"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <182..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68783.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       218..251
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           59 a           93 c           72 g           65 t
ORIGIN      
        1 acatggggac aacggctttg tgtactggta ccagcagcgg ccgggcagcg ctcccaccac
       61 tgtgatttac aaagataacc aaagaccctc tggggtccct gatcggttct ctggctccat
      121 cgacagctcc tccaactctg cctccctcac catctctgga ctgaaatctg aggacgaggc
      181 tgactattac tgtcagtctt atgacagcag cagtgtatta ttcggaggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003046             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:10283:16334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003046
VERSION     KCWK01003046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10283:16334"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68784.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          106 a          137 c          120 g          100 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatactcagt ggttccagca gcagccaggc caggcccctt tcctggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccacttcagg
      301 gacaacaatt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagta gacagcagtg gaaatcttcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003047             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:13996:4309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003047
VERSION     KCWK01003047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13996:4309"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..404
                     /note="immunoglobulin light chain variable region"
     V_region        87..404
     V_segment       87..370
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68785.1"
                     /translation="DYYCYSSDSNSKWLF"
     J_segment       376..404
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>446
                     /gene="IGLC"
BASE COUNT           98 a          138 c          114 g           96 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tagcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagatgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcaa aaaaaatata
      181 cttattggtt cccgcagaag gcaggccagc cccctatggt gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aaggtgacta ctactgttac tcatcagaca
      361 gcaatagtaa atggctattc gacggaggga cccggctgac cgtcgtaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003048             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:17313:4766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003048
VERSION     KCWK01003048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17313:4766"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68786.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          138 c          121 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccacttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003049             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:15651:10909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003049
VERSION     KCWK01003049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15651:10909"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68787.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       392..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          141 c          137 g          100 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gttctgcggc ctcctatgat ctgactcagc
      121 caccctcgat ttcagcgtcc ccaggacaga cggccagggt cacctgtggg ggagacaaca
      181 tcggaggtga agttgtgaat tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tctatggtga tagcgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacgcggc caccctgacc atcagcgggg tcgaggccgg agatgaggct gactattact
      361 gtcaggtgtg ggaccttaat agtcatcatc tcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003050             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:9951:14866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003050
VERSION     KCWK01003050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9951:14866"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68788.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          159 c          120 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacgag ccccaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003051             328 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:9400:9609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003051
VERSION     KCWK01003051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 328)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9400:9609"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..290
                     /note="immunoglobulin light chain variable region"
     V_region        8..290
     V_segment       8..253
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>262
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68789.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       256..290
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        291..>328
                     /gene="IGLC"
BASE COUNT           70 a           90 c          101 g           67 t
ORIGIN      
        1 acatggggga cagacggcca ggatcacctg tgggggagac aacattggaa gtaatagtgt
       61 gcattggtac cagcagaagc caccgcgggc ccctgtattg gtcatctctg ttgatagcga
      121 acggccctca gggatccctg agcgattctc tggttccaga tcagggaaca ccgccaccct
      181 gaccatcagc ggggtcgagg ccggggatga ggctgactat tactgtcagg tgtgggataa
      241 tatttataaa tacgcggtat tcggcggagg gacccggctg accgtcctag gtcagcccaa
      301 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003052             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:6155:14369
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003052
VERSION     KCWK01003052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6155:14369"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68790.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          155 c          122 g          113 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggttcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 gagcagtgat attggctatt ataacgctgt gtcttggtac caacagcatc caggcaaagc
      241 ccccaaactc atcatttttg acgtcattaa gcggccctca ggggtctctg atcgcttcgc
      301 tgcctccaag tctggcgaca cggcctccct gaccatctct gggctccggg ctgaggatga
      361 ggctgattat tactgcagct catatgccgg cagaaataat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003053             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:23523:13998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003053
VERSION     KCWK01003053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23523:13998"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    40..388
                     /note="immunoglobulin light chain variable region"
     V_region        40..388
     V_segment       40..351
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <316..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68791.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       352..388
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           89 a          145 c           95 g           97 t
ORIGIN      
        1 acatgggtgc tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg
       61 gcctccctct cagcaactcc tggagcatca gccagtctca catgcacctt cagcggtggc
      121 atcaatgttg ctgcctacca catacactgg taccagcaga agccagggag tcccccccgg
      181 tatcttctga gttacaaatc agactcacat aagggccagg gctctggagt ccccagccgc
      241 ttctctggat ccaaaaatgc ttcaacaaac acaggcattt tacacatctc tgggctccag
      301 tctgaggatg aggctgacta tttctgtgcc attggacaca gcagcggtcc ttacatcttc
      361 ggtgctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      421 ttcccg
//
LOCUS       KCWK01003054             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:8232:14993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003054
VERSION     KCWK01003054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8232:14993"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68792.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          152 c          117 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta ataatgtgtc ctggtaccag cacctcccag gaacagctcc caaactcctc
      241 atctattata atgatcaacg aggctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcgt gggatgatag gctgagcagt tacatcttcg ctgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003055             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:11005:12412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003055
VERSION     KCWK01003055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11005:12412"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..455
                     /note="immunoglobulin light chain variable region"
     V_region        110..455
     V_segment       110..416
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68793.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       418..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           90 a          169 c          122 g          112 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      181 gagcagtgac ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag
      241 cgctcccagg ttattcctgt actactactc cgactcagac aaacagctgg gacctggggt
      301 ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc
      361 tgggctccag cctgaggacg aggccgatta tttctgccag ctgtttgaca gtagtgttgt
      421 gttcttcgga ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01003056             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:5569:18085
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003056
VERSION     KCWK01003056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5569:18085"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..409
                     /note="immunoglobulin light chain variable region"
     V_region        88..409
     V_segment       88..373
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68794.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       377..409
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           91 a          138 c          125 g           93 t
ORIGIN      
        1 acatggggca gcattgacgg tgcctcagcc atggcctgga cccttctcct cctcggcctc
       61 ctcgcttact gcacaggctc tgcgacttcc tatgaattga ctcagtcacc ctcagtgtca
      121 gcggcctcag gacagccggc caggatcacc tgtgggggag acaacattgg aactaaaact
      181 gtgcactggt accaacagaa gccaccgcag ggccctgtat tggtcatctt tgctgatagt
      241 agacggccct cagggatccc tgagcgattc tctggctcca attcagggaa caccgccacc
      301 ctgaccatca gcagggtcga ggccggggat gaggctgact attactgtca ggtgtgggac
      361 agtagtagta aatggatatt cggcgggggg acccggctaa ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003057             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:21884:12505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003057
VERSION     KCWK01003057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21884:12505"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68795.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          156 c          121 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacgct ttattcttcg gaggagggac
      421 ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003058             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:21432:13084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003058
VERSION     KCWK01003058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21432:13084"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68796.1"
                     /translation="DYYCQVYDSSAHVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           92 a          162 c          124 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg acgcagccac
      121 cctccctgtc tgcatccccg ggagcaccgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg cagtaaaagc atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tatttctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gatcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tatatgacag tagtgctcat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003059             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:22680:8338
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003059
VERSION     KCWK01003059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22680:8338"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..424
                     /note="immunoglobulin light chain variable region"
     V_region        101..424
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68797.1"
                     /translation="DYYCQSGDSSGNHWVF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>463
                     /gene="IGLC"
BASE COUNT          104 a          136 c          124 g           99 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctctgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 gccaaaaaaa tttactcagt ggttccagca gaagccaggc caggcccctc tgctggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagaga ttctctagct ccagttcagg
      301 gccaacagtt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagga gacagcagtg gtaatcattg ggtattcggc ggagggaccc ggctaagcgt
      421 cctacgtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003060             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:8757:6757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003060
VERSION     KCWK01003060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8757:6757"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68798.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          159 c          120 g          108 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagatacag atcagactca gataagggcc agggctctgg agtccccagc cggttctctg
      301 gatccaaaga tgctgcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tccttacttc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003061             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20876:22461
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003061
VERSION     KCWK01003061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20876:22461"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..404
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68799.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          157 c          123 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctccggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagtagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003062             284 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:23977:8430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003062
VERSION     KCWK01003062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 284)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23977:8430"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..246
                     /note="immunoglobulin light chain variable region"
     V_region        5..246
     V_segment       5..207
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <174..>218
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68800.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       209..246
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        247..>284
                     /gene="IGLC"
BASE COUNT           55 a           86 c           71 g           72 t
ORIGIN      
        1 acatgggggg tttttatgtg tcctggtacc agcagttccc tggaacagcc cccaaactcc
       61 tcatctttga aaataataag cgaccctcag gggtttctga ccgattctct ggctccaagt
      121 ctggttcctc agcctccctg accatcactg gactccagtc tgaggatgag gctgattatt
      181 actgctcatc atgggaaagc agcctgaatt gggttttcgg cggagggacc cggctgaccg
      241 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003063             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:11225:17812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003063
VERSION     KCWK01003063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11225:17812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68801.1"
                     /translation="DYYCCSYGGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          152 c          120 g          114 t
ORIGIN      
        1 acatgggggc ttggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcttccct gaccatctct ggcctccaga ctgaggatga
      361 ggctgattat tactgctgct catatggagg cagcaatagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003064             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:12881:6867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003064
VERSION     KCWK01003064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12881:6867"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..401
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68802.1"
                     /translation="DYYCSLYAGSNTLFF"
     J_segment       406..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           90 a          154 c          119 g          111 t
ORIGIN      
        1 acatggggct gggatctcag gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccccgact
      121 cagactccct ctgtgtccgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgata ttgggtatta tcatgctgtg tcttggtacc aacatcatcc aggcaaagcc
      241 cccaaactca tgatttatga ggtcaataaa cggcccgcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccagac tgaggatgag
      361 gctgattatt actgcagctt atatgcaggc agcaacactt tattcttcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003065             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:25121:3921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003065
VERSION     KCWK01003065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:25121:3921"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..274
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68803.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       281..314
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           77 a          103 c           91 g           81 t
ORIGIN      
        1 acatggggga gcatcagcca gtctcacatg caccttcagc ggtggcatca ctgttgctgg
       61 ctaccatata tattggtacc agcagaagcc agggagtccc ccccggtatc ttctgaggta
      121 caaatcagac tcagataagg gccagggctc tggagtcccc agccgcttct ctggatccaa
      181 agatgcttca gcgaacacag ggattttacg catatctgga ctccagtctg aggatgaggc
      241 tgactattac tgtgccattg gacacagcag cggtgattat atcttcggtg ctgggacccg
      301 tctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01003066             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:26702:13616
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003066
VERSION     KCWK01003066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:26702:13616"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68804.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       390..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>462
                     /gene="IGLC"
BASE COUNT           90 a          144 c          132 g           96 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacagac tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtgaag ttgttaactg gtaccagcag aagccaccgc aggcccctgt cctggtcatc
      241 tatgctaata acgaacggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacacggcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg gcgttactag tgatcatccc ttattcggag gagggacccg gctgaccgtc
      421 caaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003067             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:19451:13274
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003067
VERSION     KCWK01003067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:19451:13274"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..434
                     /note="immunoglobulin light chain variable region"
     V_region        108..434
     V_segment       108..398
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68805.1"
                     /translation="DYYCQSADGNYRVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          164 c          120 g          102 t
ORIGIN      
        1 acatgggggc tgtgactcag aaagcagagc ctggggcgtc tccaccatgg cctgggctcc
       61 actcctcctc accctcctcg ctcactgcac agggtcttgg gctgaactta tgttcactca
      121 gccccattct gtgtcggggt ctccggggca gacggtcacc atctcctgca cccgcagcat
      181 tggcaacatt gacagtgaat atgtgcagtg gtaccagcag cgcccgggca gtgcccccac
      241 cacactgatt tacaaagata cccaaagacc ctctggggtc cctgatcggt tctctggctc
      301 catcgacagc tcctccaact ctgcctccct cgccatctct gggctacagt ctgaggacga
      361 ggctgactac tactgtcagt ctgctgatgg caactacagg gtcttcggcg gagggacccg
      421 tctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003068             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:13232:18151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003068
VERSION     KCWK01003068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13232:18151"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..398
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68806.1"
                     /translation="DYFCGAAYGSGSSWQWVF"
     J_segment       399..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           95 a          149 c          132 g           97 t
ORIGIN      
        1 acatggggga tcctggcttc agaagcagca tctgggacat gtcagccatg gcctggacgc
       61 ctctcctcct cagcctcctc gctcactgca caggctctgt ggcctcctat gagctgactc
      121 agccaccctc agtgtcggtg tccccaggac agacagccag catcacctgc tctggaaata
      181 aattggggaa tgtatatact tactggttcc agcagaagcc aggccaggcc cctatagtgg
      241 tcatctacaa agataccaac cggccctcag ggatccctga gcgattctct ggctccgact
      301 cagggaacac ggccaccctg accatcagca gggtcgaggc tggggatgag gccgactatt
      361 tttgtggtgc agcctatggc agtggcagca gctggcagtg ggtattcggc ggagggaccc
      421 ggctaatcgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003069             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:24919:15948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003069
VERSION     KCWK01003069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:24919:15948"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68807.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       414..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          155 c          127 g          113 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc ctctcctgca
      181 ctgggagcag ctccaacatt ggagattatt ttgtgcagtg gtaccagcag cttccaggaa
      241 cggcccccaa actcctcatc tatgaaaatc ataagcgacc ctcaggggtt tctgatcgat
      301 tctctggctc ccagtctggt acctcagcct ccctgaccat cactggactc cagtctgagg
      361 atgaggctga ttattactgc cagtcctatg acagtagttt gagtgctgta ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003070             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:6887:7722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003070
VERSION     KCWK01003070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6887:7722"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68808.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          163 c          120 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccccctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003071             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12031:22692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003071
VERSION     KCWK01003071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12031:22692"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    152..311
                     /note="immunoglobulin light chain variable region"
     V_region        152..311
     V_segment       152..275
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <240..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68809.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       276..311
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        312..>350
                     /gene="IGLC"
BASE COUNT           64 a          115 c           93 g           78 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aagatcacct gctctgggat ccctgagaga ttctctggct
      181 ccagctcagg gacagtggcc accttgacta tcagtggggc ccaggtggag gatgatgctg
      241 actactactg ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc
      301 tgaccgtcct acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003072             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:18249:15510
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003072
VERSION     KCWK01003072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18249:15510"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68810.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          155 c          127 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgattc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcgggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003073             308 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:28225:16098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003073
VERSION     KCWK01003073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 308)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 308)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:28225:16098"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..270
                     /note="immunoglobulin light chain variable region"
     V_region        8..270
     V_segment       8..233
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <195..>242
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68811.1"
                     /translation="DYYCQSGDSSGNHWVF"
     J_segment       234..270
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        271..>308
                     /gene="IGLC"
BASE COUNT           78 a           81 c           87 g           62 t
ORIGIN      
        1 acatgggctg ctgtggagaa atactggcaa aaaaatatac tcagtggttc cagcagaagg
       61 caggccaggc ccctctgctg gtgatatata aagacagtga gaggccctca gggatccctg
      121 agagattctc tagctccagt ccagggccaa catttacctt gaccaacagt ggggcccagg
      181 cagaagatga ggctgactat tactgtcaat caggagacag cagtggtaat cattgggtat
      241 tcggcggagg gacccggcta agcgtcctag gtcagcccaa ggctgccccc tcggtcactc
      301 tcttcccg
//
LOCUS       KCWK01003074             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:18403:13144
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003074
VERSION     KCWK01003074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18403:13144"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68812.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       412..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           92 a          151 c          128 g          116 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcagtatttc
      181 ttgcactggg agcagctcca acattggagg ttattatgtg cagtggtacc agcagcttcc
      241 aggaacggcc cccaaactcc tcatctatga aaatgataaa cgaccctcag ggatttctga
      301 tcgattctct ggctcccagt ctgattcctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agcttgagtg ttgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01003075             314 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:9844:13426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003075
VERSION     KCWK01003075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 314)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9844:13426"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..276
                     /note="immunoglobulin light chain variable region"
     V_region        6..276
     V_segment       6..237
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <204..>248
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68813.1"
                     /translation="VYYCAIGHSSGLYIF"
     J_segment       239..276
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        277..>314
                     /gene="IGLC"
BASE COUNT           62 a           95 c           83 g           74 t
ORIGIN      
        1 acatgggcat caatgttgct gtctaccacg tacactggta ccagcagaag ccagggagtc
       61 ccccccggta tcttctgagg tacaaatcag actcagataa gggccagggc tctggggtcc
      121 ccagccgctt ctctggatcc agtaatgctt cagcgaacac agggatttta cgcatttctg
      181 ggctccagtc tgaggatgag gctgtctatt actgtgccat tgggcacagc agcggtcttt
      241 acatcttcgg tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg
      301 tcactctgtt cccg
//
LOCUS       KCWK01003076             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:9142:12166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003076
VERSION     KCWK01003076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9142:12166"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..252
                     /note="immunoglobulin light chain variable region"
     V_region        8..252
     V_segment       8..215
                     /gene="IGLV3-35"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <177..>224
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68814.1"
                     /translation="DYYCGSWDNSGKHYIF"
     J_segment       216..252
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        253..>290
                     /gene="IGLC"
BASE COUNT           65 a           85 c           75 g           65 t
ORIGIN      
        1 acatgggcaa aacctattac acaagctggt accaacagaa gccaggccag gtccctgtgc
       61 tggtcatcta tggtaacacc aataggccct cagggatccc aggccgattc tctggctcct
      121 ggtcaggaaa ctcaggttcc ttgaccatca ctggcgctca ggtggaagat gaggctgact
      181 attactgtgg ctcctgggat aacagtggta agcattacat cttcggtgat gggacccggt
      241 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003077             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:19846:17089
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003077
VERSION     KCWK01003077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19846:17089"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..376
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68815.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       388..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          147 c          132 g           94 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctttgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaattaaa tttgtccact ggtaccagca gaagccagcg caggcccctg tgaaggtcat
      241 ctatgctgat gacaaacggc cctcagggat ccctgagaga ttctctggct ccaattcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattcctg
      361 tcaggtgtgg gacagtgaga ctgatcatta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003078             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:24109:3838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003078
VERSION     KCWK01003078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24109:3838"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..418
                     /note="immunoglobulin light chain variable region"
     V_region        101..418
     V_segment       101..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68816.1"
                     /translation="DYYCYSSDSNSKWLF"
     J_segment       390..418
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>460
                     /gene="IGLC"
BASE COUNT           98 a          141 c          123 g           98 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatagcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgaga tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttcccgca gaaggcaggc cagcccccta tggtgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttactcatca gacagcaata gtaaatggct attcgacgga gggacccggc tgaccgtcgt
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003079             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:12103:12797
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003079
VERSION     KCWK01003079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12103:12797"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68817.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          159 c          120 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaccgag cctcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003080             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:15813:14718
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003080
VERSION     KCWK01003080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:15813:14718"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68818.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          160 c          123 g          112 t
ORIGIN      
        1 acatggggtg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga ggccagggag cgctcccagg
      241 ttattcctgt attactactc cgactcatac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaggtaac acagcgtttt tgctcatctc tggactccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01003081             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:23868:17535
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003081
VERSION     KCWK01003081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23868:17535"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..378
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68819.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       380..416
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           90 a          144 c          125 g           95 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacttttc tcctcctcgg
       61 cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc caccctcggt
      121 gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca ttggaagtca
      181 aagtgtgcac tggtaccagc acaagccacc gcaggcccct gtactggtca tcttttatta
      241 taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag ggaacaccgc
      301 caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg
      361 ggacacaact attgatcacg gcttattcgg aggagggacc cggctgaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003082             373 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:8728:19399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003082
VERSION     KCWK01003082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 373)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8728:19399"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..335
                     /note="immunoglobulin light chain variable region"
     V_region        11..335
     V_segment       11..298
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <260..>307
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68820.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       301..335
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        336..>373
                     /gene="IGLC"
BASE COUNT           88 a          109 c           98 g           78 t
ORIGIN      
        1 acatggggcc tcctatgagg tgacacagtc accctcagtg tcagtgtccc caggacagac
       61 ggccaggatc acctgctctg gagcaatact ggcaaataat tatgctcagt ggttccagca
      121 gaagccagac caggcccctg tgttggtgat atataaagac actgagaggc cctcagggat
      181 ccctgagcga ttctctagct ccagttcagg gacaacaatt accttgacca tcagtggggc
      241 ccaggcagaa gatgaggctg actattactg tcaatcagtt gacagcagtg cccatcatcc
      301 gttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      361 cactctcttc ccg
//
LOCUS       KCWK01003083             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:16484:10320
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003083
VERSION     KCWK01003083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16484:10320"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68821.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           97 a          154 c          126 g          106 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agactccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gatccaacat cggaagaaat agtgtatcct ggtaccagaa gctcccagga
      241 acagctccca aactcctcat ctattacagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagcgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta cattttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003084             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:23098:13443
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003084
VERSION     KCWK01003084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23098:13443"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..417
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68822.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       418..454
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           93 a          158 c          125 g          116 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact tcacagttcc agggtcctgg
      121 gcccagtctg tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc
      181 atctcctgca ctgggagcag ctccaacatt ggagattatt ttgtgcagtg gtaccagcac
      241 cttccaggaa cggcccccaa actcctcatc tatgaaaata ataagcgacc ctcagggatt
      301 tctgatcgat tctctggctc ccagtctgga acctcagcct ccctgaccat cactggactc
      361 cagtctgagg atgaggctga ttattactgc cagtcctatg acagcagttt gattgctgtg
      421 ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCWK01003085             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:10343:12184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003085
VERSION     KCWK01003085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10343:12184"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68823.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          106 a          136 c          121 g          100 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatactcagt ggttccagca gcagccaggc caggcccctt tcctggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacaatt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagta gacagcagtg gaaatcttcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003086             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:15238:8714
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003086
VERSION     KCWK01003086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15238:8714"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68824.1"
                     /translation="DYYCQVWDSTSKWTF"
     J_segment       393..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          144 c          132 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag tcggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtaaacg gccgtcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtac tagtaaatgg acattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003087             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:21925:19877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003087
VERSION     KCWK01003087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21925:19877"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68825.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       400..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          157 c          123 g          106 t
ORIGIN      
        1 acatggggtg gggtctcagg aggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggttat aactatgtct cctggtacca acagcatcca ggcacagccc
      241 ccaaagtcat gatttatgag gtcagtaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tatacaggca tcaacagtta catcttcggt ggtgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003088             360 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:10290:22675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003088
VERSION     KCWK01003088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 360)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 360)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..360
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:10290:22675"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..322
                     /note="immunoglobulin light chain variable region"
     V_region        8..322
     V_segment       8..283
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <253..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68826.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       285..322
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>360
                     /gene="IGLC"
BASE COUNT           73 a          110 c           97 g           80 t
ORIGIN      
        1 acatgggctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
       61 agtgttggta gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta
      121 ttcctgtact actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      181 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      241 gaggacgagg ccgattattt ctgccaggtg tttgacagta gtgttgtgtt cttcggagga
      301 gggacccgac tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003089             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:6047:4980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003089
VERSION     KCWK01003089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:6047:4980"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68827.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          159 c          114 g          112 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc gtctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003090             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:18035:13426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003090
VERSION     KCWK01003090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18035:13426"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..237
                     /note="immunoglobulin light chain variable region"
     V_region        8..237
     V_segment       8..200
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <165..>209
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68828.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       201..237
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>275
                     /gene="IGLC"
BASE COUNT           56 a           86 c           70 g           63 t
ORIGIN      
        1 acatggggaa gccagggagt cccccccggt atcttctgag ttacaaatca gactcagata
       61 agggccaggg ctctggagtc cccagccgct tctctggatc caaaaatgct tcaacgaacg
      121 caggcatttt tcacatctct gggctccagt ctgaggatga ggctgactat ttctgtgcca
      181 ttggacacag cagcggtcct tacatcttcg gtgctgggac ccggctcacc gtcctaggtc
      241 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003091             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:3546:8918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003091
VERSION     KCWK01003091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:3546:8918"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68829.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          138 c          134 g          103 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcaag
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003092             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:14837:11335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003092
VERSION     KCWK01003092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14837:11335"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68830.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           88 a          157 c          127 g          109 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccgggaag agggtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcgccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01003093             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:5441:18234
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003093
VERSION     KCWK01003093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5441:18234"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68831.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          154 c          119 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgtcag gagcagtgtc gccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattatg atgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaggtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgcgaggt tacatcttcg gtcatgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003094             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:20970:15333
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003094
VERSION     KCWK01003094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20970:15333"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..444
                     /note="immunoglobulin light chain variable region"
     V_region        96..444
     V_segment       96..407
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68832.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       410..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          164 c          120 g          109 t
ORIGIN      
        1 acatggggcc cactgcaggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcccagcc tgtgctgacc cagccaacct
      121 ccctctcagc atctccggga gcatcagcca gactcagctg caccttgagc agtggcgtca
      181 atgtgggtta ttacagcata ttctggtacc agcagaagcc agggagtcct ccccggtacc
      241 ttctgtacta ccagtcagac tcaaggaagc accagggctc tggagtcccc agccgcttct
      301 ctggatccaa agatgcttca gccaatgcag ggctgttact gatctctggg ctccagtctg
      361 aggatgaggc tgactattac tgtgccctat ggcacagcag cgcttcttgc atcttcggtg
      421 gtgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01003095             342 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:18703:14686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003095
VERSION     KCWK01003095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 342)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18703:14686"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..304
                     /note="immunoglobulin light chain variable region"
     V_region        7..304
     V_segment       7..267
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <232..>276
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68833.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       269..304
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        305..>342
                     /gene="IGLC"
BASE COUNT           71 a          106 c           87 g           78 t
ORIGIN      
        1 acatgggtgt ccccaggagg gacagtcact ctcacctgtg cttccagcac tggagcagtc
       61 accagtggtc actctccaca ctggttccag cagaaacctg gacaagcccc caagacactg
      121 atttataata caaactacag acactcctgg actcctgccc ggttctcagg ctccctcctt
      181 gggggtaaag ctgccctgac actgtcaggt gcgcagcctg aggatgaggc tgagtattat
      241 tgtttactgt actatagtgg tgctcagctg ttattcggag gagggacccg gctgaccgtc
      301 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003096             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:13136:8530
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003096
VERSION     KCWK01003096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13136:8530"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..444
                     /note="immunoglobulin light chain variable region"
     V_region        120..444
     V_segment       120..401
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68834.1"
                     /translation="DYYCQVWDSTSDHYIF"
     J_segment       407..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          159 c          135 g           97 t
ORIGIN      
        1 acatggggga aggcacctgc cctgtctggg tctcaggagg cagcattgac ggtgcctcag
       61 ccatggcctg gacccttctc ctcctcggcc tcctcgctca ctgcacaggc tctgcgacct
      121 cctatgagct gactcagcca ccctcggtgt cagcggcctc aggacagacg gccagggtca
      181 cctgtggggg agacaacatt ggaactacgt ttgtccactg gtaccagcag aatccaccgc
      241 aggcccctgt gcaggtcatc tttgcggata acaaacggcc ctcagggatc cctgaacgat
      301 tctctggctc caactcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg
      361 atgaggctga ctattactgt caggtgtggg acagtactag tgatcattac atcttcggtg
      421 gtgggacccg cctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01003097             451 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:14842:20692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003097
VERSION     KCWK01003097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 451)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14842:20692"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..410
                     /note="immunoglobulin light chain variable region"
     V_region        89..410
     V_segment       89..376
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <338..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68835.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       379..410
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>451
                     /gene="IGLC"
BASE COUNT           88 a          141 c          127 g           95 t
ORIGIN      
        1 acatgggggc agcattgacg gtgcctcagc catggcctgg acttttctcc tcctcggcct
       61 ccttgcttac tgcacagact ctgcggcctc ctatgatctg actcagccac cctcggtgtc
      121 agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg gaagtgaagt
      181 tgttaactgg taccagcaga agccaccgca ggcccctgtc ctggtcatct atgctaataa
      241 cgaacggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga acacggccac
      301 cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc aggtgtgggg
      361 cgttactagt gatcatccct tattcggagg agggacccgg ctgaccgtcc aaggtcagcc
      421 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003098             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:14199:10586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003098
VERSION     KCWK01003098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14199:10586"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68836.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       400..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          156 c          128 g          101 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcgtctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttctgt tcacgcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgtaccc gcagcagagg
      181 caacattgac aatagttatg tgcagtggta ccagcagcgc ccgggcagtg ccccgaccac
      241 agtgatttac agagataacc aaagagcctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctggg ctgaagtctg gggacgaggc
      361 tgactactac tgtcagtcta ctgatggcaa ctacaatcgg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003099             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:13430:7136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003099
VERSION     KCWK01003099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:13430:7136"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68837.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       412..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          161 c          125 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct cccagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gacgatagcc tgcgcggcta tatcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003100             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:2798:12896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003100
VERSION     KCWK01003100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:2798:12896"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68838.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          155 c          121 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaacg cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003101             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:23491:14862
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003101
VERSION     KCWK01003101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23491:14862"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..312
                     /note="immunoglobulin light chain variable region"
     V_region        8..312
     V_segment       8..275
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68839.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       276..312
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>350
                     /gene="IGLC"
BASE COUNT           75 a          105 c           93 g           77 t
ORIGIN      
        1 ccatgggggg agcatcggcc agactcccct gcaccctgag cagtgacctc agtgttggta
       61 ataaaaacat gtactggtac caacagaagc cagggagcgc tcccaggtta ttcctgtact
      121 actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc tctggctcca
      181 aggagacctc aactaacaca gcgtttttgc tcatctctgg gctccagcct gaggacgagg
      241 ccgattatta ctgtcaggtg tttgacagta gtgctgtgtt attcggagga gggacccgac
      301 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003102             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18369:10086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003102
VERSION     KCWK01003102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18369:10086"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68840.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           84 a          150 c          137 g           94 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gactctgcgg cctcccatga tctgactcag
      121 ccaccctcgg tgaccgtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attcgaagtg aagttgtgaa ctggtaccag cagaagccag cgcaggcccc tgtattggtc
      241 atctttgctg ataccgaacg gcccgcaggg atccccgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catccgcggg gtcgaggccg gggatgaggc tgacttttac
      361 tgtcaggtgt gggacattcg tagtgatcgt ccgctattcg gcggagggac ccggctcacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003103             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:25079:6788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003103
VERSION     KCWK01003103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:25079:6788"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68841.1"
                     /translation="DYYCQVWDSSSDHYIF"
     J_segment       394..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          149 c          132 g           96 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gttgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccaggg tcacctgtgg gggagacaac
      181 attggaacta cgtttgtgca ctggtaccag cagaatccac cgcaggcccc tgtgcagctc
      241 atctttgcgg ataacaaacg gccctcaggg atccctgaac gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtgatcat tatatcttcg gtggtgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003104             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10987:12645
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003104
VERSION     KCWK01003104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10987:12645"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68842.1"
                     /translation="DYYCAIWHSSAYIF"
     J_segment       400..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           96 a          159 c          109 g          109 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca ggcagactca gctgcacctt gagcagtgac atcaatgttg
      181 gtacttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctgt
      241 actacaactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcaggacttt tactgatctc tggtctccgg tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgctta catcttcggt actgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003105             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:20237:13816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003105
VERSION     KCWK01003105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20237:13816"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68843.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          162 c          109 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag cattttctgg taccaccaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggtt
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtcctggga
      421 cccgggtcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003106             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:12836:3514
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003106
VERSION     KCWK01003106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12836:3514"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68844.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       384..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           90 a          143 c          124 g          101 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagccgg ccaggatcac ctgctctgga gatgtattgc
      181 caaaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgta ttggtcatct
      241 ctgaggacac caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcagcaga cagtagtggt catggcttct tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003107             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:27468:6539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003107
VERSION     KCWK01003107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:27468:6539"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68845.1"
                     /translation="DFHCQVWDIRSDRPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           82 a          148 c          138 g           95 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tccgtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tcgaagtgaa gttgtgaact ggtaccagca gaagccagcg caggcccctg tgttggtcat
      241 ctttgctgat accgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tccgcggggc cgaggccggg gatgaggctg actttcactg
      361 tcaggtgtgg gacattcgta gtgatcgtcc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003108             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:12334:18631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003108
VERSION     KCWK01003108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12334:18631"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68846.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           94 a          142 c          132 g           92 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgaac tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaattaaa actgtacact ggtaccagca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgat agtaagcggc ccacagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003109             284 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:16535:6631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003109
VERSION     KCWK01003109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 284)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16535:6631"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..246
                     /note="immunoglobulin light chain variable region"
     V_region        7..246
     V_segment       7..206
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <174..>218
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68847.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       209..246
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        247..>284
                     /gene="IGLC"
BASE COUNT           62 a           85 c           76 g           61 t
ORIGIN      
        1 acatggggta ccaacagaag ccagggagtc ccccccggta tcttctgagg tacaaatcag
       61 actcagataa gggccagggc tctggagtca ccagccgctt ctctggatcc aaagatgctt
      121 cagcgaacac agggatttta cgcatctctg ggctccagtc tgaggatgag gctgactatt
      181 actgtgccat tgggcacagc agcggtgatt acatcttcgg tgctgggacc cgactcaccg
      241 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01003110             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:5899:14490
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003110
VERSION     KCWK01003110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5899:14490"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68848.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       417..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           87 a          156 c          128 g          114 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accctctcct
      181 gcactgggag cagctccaac attggagatt attttgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctatgaaa atcataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagtag tttgagtgct gtattgttcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003111             376 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:15384:8229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003111
VERSION     KCWK01003111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 376)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15384:8229"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..338
                     /note="immunoglobulin light chain variable region"
     V_region        14..338
     V_segment       14..300
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <263..>310
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68849.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       302..338
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        339..>376
                     /gene="IGLC"
BASE COUNT           79 a          118 c          105 g           74 t
ORIGIN      
        1 acatggggcg gcctcctatg atctgactca gccaccctcg gtgtcagtgt ccccaggaca
       61 gacggccagg atcacctgtg ggggagacaa cattggaagt caaagtgtgc actggtacca
      121 gcacaagcca ccgcaggccc ctgtactggt catcttttat tataccgaac ggccctcagg
      181 aatccctgag cgattctctg gctccaaatc agggaacacc gccaccctga ccatcagcgg
      241 ggtcgaggcc ggggatgagg ctgactatta ctgtcaggtg tgggacacaa ctattgatca
      301 cggcttcttc ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      361 ggtcactctc ttcccg
//
LOCUS       KCWK01003112             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:22802:21763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003112
VERSION     KCWK01003112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22802:21763"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..313
                     /note="immunoglobulin light chain variable region"
     V_region        7..313
     V_segment       7..276
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <241..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68850.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       277..313
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>351
                     /gene="IGLC"
BASE COUNT           70 a          106 c           94 g           81 t
ORIGIN      
        1 atggggggag catcagccag tctcacatgc accttcagcg gtggcatcaa tgttgctgtc
       61 taccacgtac actggtacca gcagaagcca gggagtcccc cccggtttct tctgaggtac
      121 aaatcagact cagataaggg ccagggctct ggagtcccca gccgcttctc tggatccagt
      181 aatgtttcag cgaacacagg gattttacgc atttctgggc tccagtctga ggatgaggct
      241 gactattact gtgccattgg gcacagcagc ggtccttaca tcttcggtgc tgggacccgg
      301 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01003113             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:12388:3742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003113
VERSION     KCWK01003113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12388:3742"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68851.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           83 a          165 c          123 g          100 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggc
      181 cactacagct acaccatcgc atggcatcag cagcaacaag ggaaggcccc tcggttcttg
      241 atgtggctta agagtgatgg cagccacacc aagggggacg gggtccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccggtc tgaggatgag
      361 gctgattatt actgtcagac ctgggacatt ggcatttggg tattcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003114             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:24993:11319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003114
VERSION     KCWK01003114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24993:11319"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..426
                     /note="immunoglobulin light chain variable region"
     V_region        80..426
     V_segment       80..391
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68852.1"
                     /translation="DFFCAIGHSSGPYIF"
     J_segment       392..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>466
                     /gene="IGLC"
BASE COUNT           87 a          162 c          110 g          107 t
ORIGIN      
        1 acatggggag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc tcctctctca
       61 ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct cagcaactcc
      121 tggagcatca gccagtctca cgtgcacctt cagcggtggc atcaatgttg ctggctacca
      181 catccactgg taccagcaga agccagggag tcccccccgg tatcttctga gtaacaaatc
      241 agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat ccaaagatgc
      301 ttcaacgaac acaggcattt tacacatctc tgggctccag tctgaggatg aggctgactt
      361 tttctgtgcc attgggcaca gcagcggtcc ttacatcttc ggtgctggga cccggctcac
      421 cgtcctcggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003115             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:25089:7842
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003115
VERSION     KCWK01003115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:25089:7842"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..330
                     /note="immunoglobulin light chain variable region"
     V_region        8..330
     V_segment       8..292
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <255..>302
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68853.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       298..330
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        331..>368
                     /gene="IGLC"
BASE COUNT           77 a          110 c          112 g           69 t
ORIGIN      
        1 acatgggcta tgatctgact cagccaccct cggtgtcagt gtccccagga cagacggcca
       61 ggatcacctg cgggggagac aagattggaa gtgaagttgt gaactggtac cagcagaagc
      121 cagcgcacgc ccctgtgctg gtcatctatg ctaatagcga acggccctca gggatccctg
      181 agcgattctc tggctccaaa tcagggaaca cggccaccct gaccatcagc ggggtcgagg
      241 ccgggggtga ggctgactat tactgtcagg tgtgggacat gcgtagtgat caaccgctat
      301 tcggcggagg gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      361 tcttcccg
//
LOCUS       KCWK01003116             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:10910:16415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003116
VERSION     KCWK01003116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10910:16415"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68854.1"
                     /translation="AYYCQVWDSDSDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          148 c          131 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attgggacta attttgtgta ctggtaccag cagaagccag cgcaggcccc tatgcaggtc
      241 atctatgctg ataacaaacg gccctcaggg atccctgaga gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctattac
      361 tgtcaggtgt gggacagtga tagtgatcat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003117             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:20023:3747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003117
VERSION     KCWK01003117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20023:3747"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..416
                     /note="immunoglobulin light chain variable region"
     V_region        99..416
     V_segment       99..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68855.1"
                     /translation="DYYCYSSDSNSKWLF"
     J_segment       388..416
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>458
                     /gene="IGLC"
BASE COUNT           99 a          141 c          121 g           97 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catagcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagatg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 caaaaaaata tacttattgg ttcccgcaga aggcaggcca gccccctatg gtgatcatct
      241 atgaggacac caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactctc agtggggccc aggtggagga tgaaggtgac tactactgtt
      361 actcatcaga cagcaatagt aaatggctat tcgacggagg gacccggctg accgtcgtag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003118             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:19176:11793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003118
VERSION     KCWK01003118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19176:11793"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68856.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          147 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccaaca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003119             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:4367:13869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003119
VERSION     KCWK01003119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:4367:13869"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68857.1"
                     /translation="DYYCQVYDSSAGVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          124 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactcca ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 cattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctggt gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003120             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:13158:17579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003120
VERSION     KCWK01003120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13158:17579"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68858.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          160 c          122 g          111 t
ORIGIN      
        1 acatggggtg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gaaataaaaa catatactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtcat acagcgtttt tgctcatttc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgacg atagtgctgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01003121             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:17163:4608
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003121
VERSION     KCWK01003121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:17163:4608"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..264
                     /note="immunoglobulin light chain variable region"
     V_region        6..264
     V_segment       6..227
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68859.1"
                     /translation="DYYCQVWDSSSDHVFF"
     J_segment       228..264
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>302
                     /gene="IGLC"
BASE COUNT           66 a           86 c           90 g           60 t
ORIGIN      
        1 acatgggggg agacaacatt agaagtaaaa atgtgaattg gtaccagcag aagccaccgc
       61 aggcccccgc gctggtcatc tattatgata gcgaccggcc ctcagggatc cctgagcgat
      121 tctctggctc caactcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg
      181 atgaggctga ctattactgt caggtgtggg acagtagtag tgatcatgtg tttttcggag
      241 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      301 cg
//
LOCUS       KCWK01003122             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:2671:8737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003122
VERSION     KCWK01003122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:2671:8737"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68860.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          145 c          131 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtattggtc
      241 atcttttatt ataccgaacg ggcctcagga atccctgagc gattctctgg gtccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003123             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:17422:7207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003123
VERSION     KCWK01003123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17422:7207"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68861.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       406..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           89 a          156 c          130 g          103 t
ORIGIN      
        1 acatggggct ggctgtggct caggaagcag agcctggagc gtctccacca tggcctgggc
       61 tccactcctc ctcaccctcc tcgctcactg cacagggtct tgggctgagg ttctgttcac
      121 gcagccccat tctgtgtcgg ggtctccggg gcagacggtc accatctcct gtacccgcag
      181 cagaggcaac attgacaata gttatgtgca gtggtaccag cagcgcccgg ggagtgcccc
      241 gaccacagtg atttacagag ataaccaaag agcctctggg gtccctgatc ggttctctgg
      301 ctccatcgac agctcctcca actctgcctc cctcaccatc tctgggctga agtctgagga
      361 cgaggctgac tactactgtc agtctactga tggcaactac aataggttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003124             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:26202:6802
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003124
VERSION     KCWK01003124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:26202:6802"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..423
                     /note="immunoglobulin light chain variable region"
     V_region        104..423
     V_segment       104..398
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68862.1"
                     /translation="DYYCQSFDSSGFWVF"
     J_segment       400..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>475
                     /gene="IGLC"
BASE COUNT           84 a          158 c          126 g          107 t
ORIGIN      
        1 acatgggggc tgtggctcag gaagcagagc ctggagcatc tccaccatgg cctgggctcc
       61 actcctcctc accctcctcg ctcactgcac agggtcttgg gctgaggttg tgttcactca
      121 gccccattct gtgtcggggt ctccggggca gacggtcacc atctcctgca cccgcagcag
      181 tggcagcatt gacaacagct atgtgtactg gtaccagcag cggccgggca gcgcccccac
      241 cactctgatt tacaaagata accaaagacc ctctggggtc cctgatcggt tctctggctc
      301 catcgacagc tcctccaact ctgcctccct caccatctct ggactgaagt ctgaggacga
      361 ggcagactat tactgtcagt cttttgacag cagcggtttt tgggtgttcg gcggagggac
      421 ccgactaagt gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003125             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:4964:9250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003125
VERSION     KCWK01003125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:4964:9250"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..393
                     /note="immunoglobulin light chain variable region"
     V_region        98..393
     V_segment       98..356
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <318..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68863.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       357..393
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>431
                     /gene="IGLC"
BASE COUNT           81 a          145 c          111 g           94 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tggacagtcg gtcaccatct
      121 cctgcactgg aaccagcagt gacatcggtg gttataacta tgtctcctgg taccaacaac
      181 atccaggcac agcccccaaa ctcgtgattt atgaggtcaa tcagcggccc tcaggggtct
      241 ctgatcgctt ctctggctcc aagtctgaca acacggcctc cctgaccatc tctggcctcc
      301 agcctgagga cgaggctgat tattactgca gctcgtatgc aggcagcgac actttcgtgt
      361 tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      421 ctctcttccc g
//
LOCUS       KCWK01003126             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:21840:16757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003126
VERSION     KCWK01003126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21840:16757"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68864.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          151 c          120 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgta accatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattatg atgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaggtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcggcat gggatgatag cctgagaggt tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003127             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:27023:6973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003127
VERSION     KCWK01003127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:27023:6973"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68865.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          130 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct gcaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003128             414 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:9213:7735
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003128
VERSION     KCWK01003128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 414)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9213:7735"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..376
                     /note="immunoglobulin light chain variable region"
     V_region        92..376
     V_segment       92..339
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <301..>348
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68866.1"
                     /translation="DYYCQVWDSSSDHVFF"
     J_segment       340..376
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        377..>414
                     /gene="IGLC"
BASE COUNT           81 a          130 c          123 g           80 t
ORIGIN      
        1 acatggggag cctgggcctc aggaagcagc cttggcggtg cctcagccat ggcctggacc
       61 cttctcctcc tcggcctcct cgctcactgc acaggacaga cggccaggat cacctgtggg
      121 ggagacgaca ctagaagtaa aaatgtgatt tggtaccagc agaagccacc gcaggccccc
      181 gcgctggtca tctattatga tagcgaccgg ccctcaggga tccctcagcg attctctggc
      241 tccaactcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct
      301 gactattact gtcaggtgtg ggacagtagt agtgatcatg tgtttttcgg aggagggacc
      361 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003129             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:17738:17451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003129
VERSION     KCWK01003129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17738:17451"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..409
                     /note="immunoglobulin light chain variable region"
     V_region        79..409
     V_segment       79..373
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <337..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68867.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       374..409
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           79 a          149 c          116 g          103 t
ORIGIN      
        1 acatgggggg acgtctccac catggcctgg gctctgctcc tcctcaccct cctcactcag
       61 ggcacaggat cctgggctca gtctgccctg actcagcctc cctcagtgtc caagtctctt
      121 ggacagtcgg tcaccatctc ctgcactgga accagcagtg acattggtgg ttatgatggc
      181 gtctcctggt accagcagca ctcagggaca gcccccagac tcctgattta tgatgtcact
      241 aagcggccct caggggtctc ggatcgcttc tctggctcca agtctggcaa cacggcctcc
      301 ctcaccatct ctgggctcca gactgaggac gaggctgatt attattgttg ctcatatagg
      361 agtggaaaca cttggctatt cggcggaggg acccggctga ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003130             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:24762:11475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003130
VERSION     KCWK01003130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24762:11475"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68868.1"
                     /translation="DYYCQVWDSDSKWVF"
     J_segment       387..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           90 a          144 c          135 g           92 t
ORIGIN      
        1 acatgggctg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgag ttgactcagc
      121 caccctcagt gtcagcggcc tcaggacaga cggccaggat cacctgtggc ggggacagcc
      181 ttggaactaa aaatgtgcac tggtaccagc agaagccagc gcaggcccct gtggtggtca
      241 tctatgttga taataaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtgat agtaagtggg tcttcggcgg agggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003131             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:10401:19387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003131
VERSION     KCWK01003131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10401:19387"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68869.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           88 a          156 c          126 g          111 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc aggccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagtctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcgccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01003132             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:15383:19978
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003132
VERSION     KCWK01003132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15383:19978"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..421
                     /note="immunoglobulin light chain variable region"
     V_region        74..421
     V_segment       74..381
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68870.1"
                     /translation="DYYCAIGHSSGNYIF"
     J_segment       388..421
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           86 a          154 c          110 g          109 t
ORIGIN      
        1 acatgggggt ccaccatggc ctggactcct ctcctcctcc tgctcctctc tcactgcaca
       61 ggttccctct cccagcctat gctgactcag ccggcctcct tctcagcatc tcctggagct
      121 tcagccagtc tcacatgcac cttcagcggt ggcatcaatg ttgctggcta ccacatacac
      181 tggtaccagc agaagccagg gagtcctccc cggtttcttc tgagatacaa gtcagactca
      241 gataagggcc agggctctgg agtccccagc cgcttctctg gatccaagga tgcttcagcg
      301 aacacaggaa ttttacgcat ctctgggctc cagtctgagg atgaggctga ctattactgt
      361 gccattgggc acagcagcgg taattatatc ttcggtgctg ggacccggct caccgtccta
      421 ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003133             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:8886:19946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003133
VERSION     KCWK01003133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:8886:19946"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68871.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       385..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           97 a          144 c          120 g           97 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gaagaattgc
      181 caaaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtc cagatcatct
      241 atgaggacag taaacggccc cctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc actggggccc aggtggagga tgaagctgac tactactgtt
      361 tctcaacaga caccagtggt aatcgggtat tcggcggagg gacccgtcta accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003134             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:16553:11405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003134
VERSION     KCWK01003134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16553:11405"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68872.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          160 c          115 g          107 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 ctgcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatacaaatc agactcagaa aaggaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ctcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ctactgtgcc attgggcaca gcagcggtga ttacattttc gctgctggga
      421 cccgcctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003135             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:14178:19692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003135
VERSION     KCWK01003135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14178:19692"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68873.1"
                     /translation="DYYCQVFDDSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          161 c          120 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccccctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata caacgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacga tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003136             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:17372:10615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003136
VERSION     KCWK01003136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17372:10615"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..396
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68874.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       401..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          154 c          116 g          109 t
ORIGIN      
        1 acatggggat ctcaggaggc agcgctctca ggacttctcc accatggtct gggctctgct
       61 cctcctcacc ctcctcactc agggcacagg atcctgggct caggctgccc cgactcagac
      121 tccctctgtg tccgggtctc ctggacagtc ggtcaccatc tcctgcactg gaaccagcag
      181 tgatattggg tattatcatg ctgtgtcttg gtaccaacat catccaggca aagcccccaa
      241 actcatgatt tatgaggtca ataaacggcc cgcaggggtc tctgatcgct tctctggctc
      301 caagtctggc aacacggcct ccctgaccat ctctgggctc cagactgagg atgaggctga
      361 ttattactgc agctcatatg caggcagcaa cactttattc ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003137             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:21732:4745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003137
VERSION     KCWK01003137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21732:4745"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68875.1"
                     /translation="DYYCSSWESSLNWLF"
     J_segment       406..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           88 a          151 c          128 g          114 t
ORIGIN      
        1 atggggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct ctccttctca ctctgctggt tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag tatctggggc ccccgggcag agggtcacca tctcctgcac
      181 tgggagcagc tccaacatcg gggcgggttt ttatgtttcc tggtaccagc agttcccagg
      241 aacagccccc aaactcctca tctttgaaaa taataaacga ccctcagggg tttctgaccg
      301 attctctggc tccaagtctg gttcctcagc ctccctgacc atcactggac tccaatctga
      361 ggatgaggct gattattatt gttcatcatg ggaaagcagc ctgaattggt tattcggcgg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01003138             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:7762:15952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003138
VERSION     KCWK01003138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7762:15952"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68876.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           86 a          154 c          123 g          106 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccgggaagag tgtctccatc tcctgttctg gaagcagctc
      181 caacatcgga agtcatagtg tctcctggta ccagcagctc ccaggaacag ctcccaaact
      241 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctctca
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcatgggatg atagcctgag cggttacatc ttcggtgctg ggacccggct
      421 cgccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003139             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:10541:2790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003139
VERSION     KCWK01003139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:10541:2790"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68877.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          158 c          126 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tcgcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcagcact cagagacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tactgttgct catataggag tggaaatact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003140             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:5909:16439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003140
VERSION     KCWK01003140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:5909:16439"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68878.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          140 c          137 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatcactga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003141             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:8839:5560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003141
VERSION     KCWK01003141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8839:5560"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68879.1"
                     /translation="DYHCQSADSSGNHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          134 c          124 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc agtggttcca gcagaagcca ggccaggccc ctgtgttggt
      241 tatatataaa gacagtgaga ggccctcagg gatccctgaa cgattctcta gttccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggta gaagatgagg ctgactatca
      361 ctgtcaatca gcagacagca gtggtaatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003142             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:20224:8553
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003142
VERSION     KCWK01003142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:20224:8553"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68880.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       408..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           86 a          154 c          131 g          112 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg gttcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agcatctggg gcccccgggc agagggttac catctcctgc
      181 actgggagca gctccaacat cggggcgggt ttttatgtgt cctggtacca gcagttccct
      241 ggaacagccc ccaaactcct catctttgaa aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggttcctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgctcatca tgggaaagca gcctgaattg ggttttcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01003143             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:9909:4666
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003143
VERSION     KCWK01003143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9909:4666"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68881.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       392..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           85 a          150 c          137 g           92 t
ORIGIN      
        1 acatggggtg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag gctctgcgac ctcctatgac ctggctcagc
      121 caccctcggt gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa ctatgtgcac tggtaccagc agaagccagc gcaggcccct gtcgagatca
      241 tctttgctga taacaaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggatcaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactatttct
      361 gtcaggtgtg gggcagtcgt agtgatcatc cggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003144             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:10390:2176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003144
VERSION     KCWK01003144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10390:2176"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..367
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68882.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       379..416
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           89 a          143 c          128 g           94 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacccttc tcctcctcgg
       61 cctcctcgct cactgcacag gctctgcgac ctcctttgag ctgactcagc caccctcggt
      121 gtcagtggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca ttggaattaa
      181 atttgtccac tggtaccagc agaagccagc gcaggcccct gtgaaggtca tctatgctga
      241 tgacaaacgg ccctcaggga tccctgagag attctctggc tccaattcag ggaacaccgc
      301 caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattcct gtcaggtgtg
      361 ggacagtgag actgatcatt acatcttcgg tgttgggacc cggctcaccg tcctaggtca
      421 gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01003145             349 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:8410:14740
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003145
VERSION     KCWK01003145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 349)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8410:14740"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    139..311
                     /note="immunoglobulin light chain variable region"
     V_region        139..311
     V_segment       139..272
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <236..>283
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68883.1"
                     /translation="DYYCSAWDSSLTGGFF"
     J_segment       274..311
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        312..>349
                     /gene="IGLC"
BASE COUNT           62 a          116 c           93 g           78 t
ORIGIN      
        1 acatggggtc agcttcagct gtggctagag aagacaggac tcaggacaat ctccagcatg
       61 gcctgcttcc ctctcatcct caccgtcctc actcactgtg caggatcctg ggcccagtct
      121 gtgctgactc aaccaccctc agcgaccctc aggggtccct gatcgattct ctggctccaa
      181 gtctggcacg tcagcctccc tggacatcag tgggctccag tccgaggatg aggctgatta
      241 ttactgctca gcatgggata gcagtctgac cggtggcttt ttcggaggag ggacccggct
      301 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003146             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:18078:16903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003146
VERSION     KCWK01003146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18078:16903"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68884.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           86 a          141 c          119 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagccggcc aggatcacct gctctggaga tgtattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtatt ggtcatctct gaggacaccg
      241 aacggccctc tgggatccct gggagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gtagtggtca tggcttcttc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003147             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:13306:14118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003147
VERSION     KCWK01003147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13306:14118"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..425
                     /note="immunoglobulin light chain variable region"
     V_region        102..425
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68885.1"
                     /translation="DYHCQVWDLNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          143 c          137 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc ccctatgatc tgacgcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccaggctg acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgac agcgagcggc cctcagggat ccctgagcga ttctctggct ctaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actatcactg
      361 tcaggtgtgg gaccttaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003148             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:7562:3094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003148
VERSION     KCWK01003148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:7562:3094"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68886.1"
                     /translation="DYYCSAWDSSLTGGLF"
     J_segment       407..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           96 a          157 c          123 g          106 t
ORIGIN      
        1 acatgaggca gcttcagctg tggctagaga agacaggact caggacaatc tccagcatgg
       61 cctgcttccc tctcatcctc accgtcctca ctcactgtgc aggatcctgg gcccagtctg
      121 tgctgactca accaccctca gcgtctgggg cccccgggca gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggatgtaatt ttgtatactg gtaccagcag ttctcaggga
      241 aggcccccaa actcctcatc cataatagta atcagcgacc ctcaggggtc cctgatcgat
      301 tctctggctc caagactggc acgtcagcct ccctggccat cagtgggctc cagtccgagg
      361 atgaggctga ctattactgc tcagcatggg atagcagtct gaccggtggc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003149             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:13914:9168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003149
VERSION     KCWK01003149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13914:9168"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68887.1"
                     /translation="NYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccaattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003150             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:6276:2907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003150
VERSION     KCWK01003150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:6276:2907"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68888.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          157 c          127 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca agtcccagga
      241 acagctccca aactcctcat ctattctagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgaggggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003151             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:24549:15942
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003151
VERSION     KCWK01003151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24549:15942"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68889.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       412..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          161 c          125 g          108 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctcgtc tcctctcctc ctcacccttt tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac acagccgccc tcagtgtctg gggccccagg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatatatc ctggtaccag cagctcccag
      241 gaacggcccc caaactcctc gtctatgaca ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag ccaccctgac catcactggg ctccagactg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag tctgagtgct cgggtattcg
      421 gcggagggac ccggctaacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003152             308 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:19641:10190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003152
VERSION     KCWK01003152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 308)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 308)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19641:10190"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..270
                     /note="immunoglobulin light chain variable region"
     V_region        8..270
     V_segment       8..234
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <198..>242
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68890.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       238..270
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        271..>308
                     /gene="IGLC"
BASE COUNT           69 a           88 c           90 g           61 t
ORIGIN      
        1 acatgggcac ctgtggggga gacaacattg gaactaaaac tgtgcactgg taccagcaga
       61 agccaccgca gggccctgta ttggtcatct ttgctgatac taaacggccc tcagggatcc
      121 ctgaacgatt ctctggctcc aacgcaggga acaccgccac cctgaccatc agcagggtcg
      181 aggccgggga tgaggctgac tattattgtc aggtgtggga cagtagtagt aaatggatat
      241 tcggcggggg gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      301 tcttcccg
//
LOCUS       KCWK01003153             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:21671:13488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003153
VERSION     KCWK01003153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21671:13488"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68891.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          100 a          137 c          125 g          104 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg aggtgacaca
      121 gtcaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagcaat
      181 actggcaaat aattatgctc agtggttcca gcagaagcca gaccaggccc ctgtgttggt
      241 gatatataaa gacactgaga ggccctcagg gatccctggg cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gttgacagca gtgcccatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003154             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:16751:4867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003154
VERSION     KCWK01003154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16751:4867"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68892.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          162 c          122 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gctagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003155             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10281:12809
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003155
VERSION     KCWK01003155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10281:12809"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68893.1"
                     /translation="DYSCCSYRSGNTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           81 a          157 c          127 g          108 t
ORIGIN      
        1 acatggggtg gggtctcagg aggcagcgct ctcgggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcagtct gccctgactc
      121 agcctccctc agtgtccaag tctcttggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat tggtggttat gatggcgtct cctggtacca gcagcactca gggacagccc
      241 ccagactcct gatttatgat gtcactaagc ggccctcagg ggtctcggat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctca ccatctctgg gctccagact gaggacgagg
      361 ctgattattc ttgttgctca tataggagtg gaaacacttg gctattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003156             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22488:16336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003156
VERSION     KCWK01003156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22488:16336"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..312
                     /note="immunoglobulin light chain variable region"
     V_region        8..312
     V_segment       8..275
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68894.1"
                     /translation="DYHCQVYDSSAVLF"
     J_segment       276..312
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>350
                     /gene="IGLC"
BASE COUNT           74 a          105 c           93 g           78 t
ORIGIN      
        1 acatgggggg agcatcggcc agactcccct gcaccctgag cagtgacctc agtgttggta
       61 ataaaaacat atactggtac cagcagaagc cagggagcgc tcccaggtta ttcctgttct
      121 acttctccga ctcagacaac cagctgggac ctggggtccc caatcgagtc tctggctcca
      181 aggagacctc aattaacaca gcgtttttgc tcatctctgg gctccagcct gaggacgagg
      241 ccgattatca ctgtcaggtg tatgacagta gtgctgtgtt attcggagga gggacccggc
      301 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003157             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:15427:15142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003157
VERSION     KCWK01003157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15427:15142"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68895.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       402..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           86 a          157 c          125 g          108 t
ORIGIN      
        1 acatggggtg gggtctcagg aggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggcggttat aactatgtct cctggtacca acaacatcca gacacagccc
      241 ccaaactcat gatttatgag gtcagtaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgctgctca catgcaggca gtgatatttt cgtgttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003158             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:19400:4072
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003158
VERSION     KCWK01003158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19400:4072"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68896.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          142 c          135 g          102 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtcaac tggtaccaac agaagccacc gcaggcccct gtggtggtca
      241 tctatgctga ttatgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcggag tcgcggccgg ggatgaggct gactattact
      361 gtcaggtttg ggacatttat actgatcatc cggtgttgtt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003159             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:25549:3254
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003159
VERSION     KCWK01003159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25549:3254"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68897.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          165 c          123 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg ccctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003160             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:28398:7325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003160
VERSION     KCWK01003160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:28398:7325"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    69..393
                     /note="immunoglobulin light chain variable region"
     V_region        69..393
     V_segment       69..356
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <318..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68898.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       359..393
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>431
                     /gene="IGLC"
BASE COUNT           82 a          131 c          124 g           94 t
ORIGIN      
        1 acatgggagc catggccggg acccttctcc tcctcggcct ccttgctcac tttacaggct
       61 ctgtggcctc ctatgagttg cctcagccac gctcagtgtc cgtgtcccca ggacagacgg
      121 ccaggatcac ctgtggggga gacaacattg gaagtaatag tgtgcattgg taccagcaga
      181 agccaccgcg ggcccctgta ttggtcatct ctgttgatag cgaacggccc tcagggatcc
      241 ctgagcgatt ctctggttcc agatcaggga acaccgccac cctgaccatc agcggggtcg
      301 aggccgggga tgaggctgac tattactgtc aggtgtggga taatatttat aaatacgcgg
      361 tattcggcgg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      421 ctctcttccc g
//
LOCUS       KCWK01003161             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:10458:18076
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003161
VERSION     KCWK01003161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10458:18076"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..403
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68899.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       405..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           97 a          152 c          114 g          117 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcgcagcctg tgctgactca gccaacctcc
      121 ctctcagcat ctcctggagc atcagccaga ctcacctgca ccttgaacag tggcatcagt
      181 gttggtaatt acaggatatt ctggtaccac cagaagccag ggagtcctcc ccggtatctt
      241 ctgaactacc acacagactc agatattcat caggggtctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatgcaggg attttactca tctctggact ccagtctgag
      361 gatgaggctg actattactg tatgatttgg cacaacaatg cttattgggt tttcggcgga
      421 gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003162             326 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:15601:12063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003162
VERSION     KCWK01003162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 326)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15601:12063"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..288
                     /note="immunoglobulin light chain variable region"
     V_region        7..288
     V_segment       7..249
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>260
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68900.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       258..288
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        289..>326
                     /gene="IGLC"
BASE COUNT           69 a          104 c           75 g           78 t
ORIGIN      
        1 acatgggggt caccatctcc tgcattagca gcagctccaa catcggggcg gcttattatg
       61 tatcctggta ccaacagttc ccaggaacag cccccaaact cctcatcttt gaaaataata
      121 agcgaccctc aggggtttct gaccgattct ctggctccaa gtctggtccc tcagcctccc
      181 tgaccatcac tggactccaa tctgacgatg aggctgatta ttactgttta gcatgggata
      241 ccagcctgaa ttggatcttc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      301 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003163             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:10154:3630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003163
VERSION     KCWK01003163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10154:3630"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68901.1"
                     /translation="DFYCQVWDMNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          139 c          138 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcaggc
      121 accctcgatt tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 gtatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg acttttactg
      361 tcaggtgtgg gacatgaaca gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003164             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:15931:11661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003164
VERSION     KCWK01003164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15931:11661"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68902.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       391..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           90 a          143 c          134 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaatt ggtaccagca gaagccaccg caggcccctg tcctggtcat
      241 ctatgctaat aacgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg ggcgttacta gtgatcatcc cttattcgga ggagggaccc ggctgaccgt
      421 ccaaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003165             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:22930:14172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003165
VERSION     KCWK01003165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22930:14172"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68903.1"
                     /translation="DYYCQVWGSRSDHPVF"
     J_segment       392..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          148 c          138 g           92 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag ggtctgcgac ctcctatgag ctgactcagc
      121 caccctcggt gtcagcggcc tcaggacaga cggccagggt cacctgtggg ggaggcaaca
      181 ttggaagtaa ttttgttcac tggtaccagc agaagccagc gcaggcccct gttcaggtca
      241 tctatgctga taacaaacgg ccctcaggga tccctgaacg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcaccgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg gggcagtcgt agtgatcatc cggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003166             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:19839:16181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003166
VERSION     KCWK01003166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19839:16181"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68904.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       403..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           92 a          159 c          111 g          113 t
ORIGIN      
        1 acatggggca gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccca gcctgtgctg acccagccaa cctccctctc
      121 agcatctccg ggagcatcag tcagactcag ctgcaccttg agcagtggca tcaatgttgg
      181 ttcttacacc atattctggt accagcagaa gccagggagt cctccccagt tccttctgta
      241 ctactactca gactcaaata atcaccaggg ctctggagtc cccagccgct tctctggatc
      301 caaagatgct tcagccaatg cagggctttt actgatctct gggctccagt ctgaagatga
      361 ggctgactat tactgtgcca tgtggcacag cagcgcttat gccttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003167             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:13160:8483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003167
VERSION     KCWK01003167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:13160:8483"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..303
                     /note="immunoglobulin light chain variable region"
     V_region        8..303
     V_segment       8..266
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68905.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       267..303
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           70 a          107 c           82 g           82 t
ORIGIN      
        1 acatgggagc cagactcagc tgcaccttga gcagtggcaa tgttggcagt tacagcatat
       61 tctggtacca gcagaagcca gggagtcctc cccggttcct tctttactac tactcagact
      121 caagtaacca ccaggactct ggagtcccca gccgcttctc tggatcgaaa gatgcttcag
      181 ccaatgcagg gcttttactg atctctgggc tccagtctga tgatgaggct gactattact
      241 gtgccacatg gcacagcagc gcttcttaca tcttcggtcc tgggacccgg ctcaccgtcc
      301 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01003168             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:26809:18900
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003168
VERSION     KCWK01003168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:26809:18900"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..413
                     /note="immunoglobulin light chain variable region"
     V_region        100..413
     V_segment       100..387
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68906.1"
                     /translation="DYFCQSGDSSGNHWVF"
     J_segment       388..413
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>462
                     /gene="IGLC"
BASE COUNT          105 a          129 c          129 g           99 t
ORIGIN      
        1 acatggggtg gttctaggag gaagagctct gggtgtctca ccatgacctg gaccactgtt
       61 ctgctcccct ttctcactct ctgcacaggc tctgaggcct cctatgagct gacacagcca
      121 ccctcagtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg aaaaatactg
      181 gcaaaaaaat atactcagtg gttccagcag aagccaggcc aggcccctct gctggtgata
      241 tataaagaca gtgagaggcc ctcagggatc cctgagagat tttctaggtc cagttcaggg
      301 ccaagggata gcttgaccat cagtggggcc caggcagaag atgaggctga ctatttctgt
      361 caatcaggag acagcagtgg taatcattgg gtattcggcg gagggacccg gctaggcgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003169             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:20152:4211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003169
VERSION     KCWK01003169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20152:4211"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68907.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          153 c          113 g          117 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgagcagt ggcttcagtg
      181 ttggtactta caggatattc tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 ttaactacca cacagactca gataagcacc aggactctgg agtccccagc cgcttctttg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttatgtctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003170             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:18566:4053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003170
VERSION     KCWK01003170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:18566:4053"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..398
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68908.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           89 a          152 c          120 g          110 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 actccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgatattg ggtattatca tgctgtgtct tggtaccagc atcatccagg caaagccccc
      241 aaactcatga tttatgaggt caataaacgg cccgcagggg tctctgatcg cttctctggc
      301 tccaactctg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 gattattact gcagctcata tggaggcagc aatagtttat tcttcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003171             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:5939:9327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003171
VERSION     KCWK01003171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:5939:9327"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..303
                     /note="immunoglobulin light chain variable region"
     V_region        6..303
     V_segment       6..264
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68909.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       266..303
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           67 a          105 c           88 g           81 t
ORIGIN      
        1 acatgggggc ccccgggcag agggtcacca tctcctgctc tgggagcagc tccaacatcg
       61 gggcgggttt ttatgtttcc tggtaccagc agttcccagg aacagccccc aaactcctca
      121 tctttgaaaa taataagcga ccctcagggg tttctgaccg attctctggc tccaagtctg
      181 gttcctcagc ctccctgacc atcactggac tccaatctga ggatgaggct gattattatt
      241 gttcatcatg ggaaagcagc ctgaattggg tattcggcgg agggacccgg ctgaccgtcc
      301 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003172             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:12355:7407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003172
VERSION     KCWK01003172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12355:7407"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68910.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          159 c          121 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagtcac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcaga tgtatgacag tagtgatgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003173             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:23329:18531
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003173
VERSION     KCWK01003173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:23329:18531"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68911.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          139 c          135 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003174             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:7665:16835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003174
VERSION     KCWK01003174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7665:16835"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68912.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       393..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>465
                     /gene="IGLC"
BASE COUNT           91 a          144 c          134 g           96 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gactctgagg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtcctggtc
      241 atctatgcta ataacgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt ggggcgttac tagtgatcat cccttattcg gaggagggac ccggctgacc
      421 gtccaaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003175             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18379:9835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003175
VERSION     KCWK01003175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18379:9835"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..443
                     /note="immunoglobulin light chain variable region"
     V_region        115..443
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68913.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>483
                     /gene="IGLC"
BASE COUNT           86 a          158 c          127 g          112 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtccag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcagttgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagtc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctgggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003176             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:13610:13557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003176
VERSION     KCWK01003176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13610:13557"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..282
                     /note="immunoglobulin light chain variable region"
     V_region        7..282
     V_segment       7..242
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <210..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68914.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       245..282
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>320
                     /gene="IGLC"
BASE COUNT           67 a           94 c           87 g           72 t
ORIGIN      
        1 acatgggcgg tggcatcaat gttgttggct accacataca ctggtaccag cagaagccag
       61 ggagtcctcc ccggtatctt ctgagataca aatcggactc agataagggc cagggctctg
      121 gagtccccag ccgcttctct ggatccaaag atgcttcagc gaacgcaggg attttacgca
      181 tctctggact ccagtctgag gatgaggctg actattactg tgccattggg cacagcagcg
      241 gtgattacat cttcggtgct gggacccggc tcaccgtcct aggtcagccc aaggcttccc
      301 ccacggtcac tctgttcccg
//
LOCUS       KCWK01003177             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:26171:3886
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003177
VERSION     KCWK01003177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:26171:3886"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68915.1"
                     /translation="DYYCGAWDSSLSGYIF"
     J_segment       410..447
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           92 a          160 c          123 g          110 t
ORIGIN      
        1 acatgggggc tctgcctcag ctgtgagcac agaaggcagg acttgggaca atcttcatca
       61 tgacctggtc ccctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtcctgac gcagccgccc tcagtgtctg cggccccagg gcagaaggtc accatctcct
      181 gctctggaag tagctccaac atcgggagaa attctgtctc ctggtaccag caggtcccag
      241 gaacggcccc caaactcctc acctatgaca atgataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag cctccctggc catcactgga ctccagactg
      361 gagatgaggc tgattattac tgcggagcat gggatagcag tctgagtggt tacattttcg
      421 gtgctgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt
      481 tcccg
//
LOCUS       KCWK01003178             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:15412:9391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003178
VERSION     KCWK01003178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15412:9391"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68916.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       391..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          148 c          135 g           93 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctatgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa tatgtgcact ggtaccagca gaagccagcg caggcccctg tgttggtcat
      241 ctatgctgat accagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggtgt cgaggccggg tatgaggctg actatttctg
      361 tcaggtgtgg gacgatagta gtgatcatcc ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003179             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:20711:5671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003179
VERSION     KCWK01003179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20711:5671"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68917.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           83 a          150 c          138 g           94 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gactctgcgg cctcccatga tctgactcag
      121 ccaccctcgg tgaccgtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attcgaagtg aagttgtgaa ctggtaccag cagaagccag cgcaggcccc tgtattggtc
      241 atctttgctg ataccgaacg gcccgcaggg atccccgggc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catccgcggg gtcgaggccg gggatgaggc tgacttttac
      361 tgtcaggtgt gggacattcg tagtgatcgt ccgctattcg gcggagggac ccggctcacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003180             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:20365:7802
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003180
VERSION     KCWK01003180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20365:7802"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68918.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           82 a          146 c          140 g           97 t
ORIGIN      
        1 acatgggggg gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtccgtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attcgaagtg aagttgtgaa ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
      241 atctttgctg ataccgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catccgcggg gtcgaggccg gggatgaggc tgacttttac
      361 tgtcaggtgt gggacattcg tagtgatcgt ccgctattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003181             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:14870:12686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003181
VERSION     KCWK01003181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14870:12686"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68919.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          143 c          131 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgtga cctcctatga attgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tctattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003182             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11256:12185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003182
VERSION     KCWK01003182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11256:12185"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..287
                     /note="immunoglobulin light chain variable region"
     V_region        6..287
     V_segment       6..250
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <212..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68920.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       251..287
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>325
                     /gene="IGLC"
BASE COUNT           68 a           99 c           78 g           80 t
ORIGIN      
        1 acatggggtc accatctcct gcactgggag cagctccaac attggagatt attttgtgca
       61 gtggtaccag caccttccag gaacggcccc caaactcctc atctatgaaa ataataagcg
      121 gccctcaggg atttctgatc gattctctgg ctcccagtct ggaacctcag cctccctgac
      181 catcactgga ctccagtctg aggatgaggc tgattattac tgccagtcct atgacagcag
      241 tttgattgct gtgttattcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc
      301 tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003183             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:19041:10538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003183
VERSION     KCWK01003183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19041:10538"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68921.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       399..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           81 a          164 c          114 g          113 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacgtt ggtggttcta actctgtctc ctggtaccaa caacacccag gcagagcccc
      241 caaactcatg atttttggtg tcaataatcg gccctctggg gtctctgacc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggc ctccagtctg aggacgaggc
      361 tgattattac tgttgttcac attcaaccag tagcacttac gtcttcggtc ctgggacccg
      421 gctcaccgtc ctgggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01003184             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:11315:7782
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003184
VERSION     KCWK01003184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11315:7782"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68922.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          163 c          122 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gatcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctagctc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003185             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14353:8189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003185
VERSION     KCWK01003185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14353:8189"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..409
                     /note="immunoglobulin light chain variable region"
     V_region        91..409
     V_segment       91..377
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68923.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       378..409
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           88 a          140 c          122 g           97 t
ORIGIN      
        1 acatggggag cagagctctg gggtgtctcc accatggcct ggactcctct ctggctcacc
       61 ctcctcagtc tttgcacagg ttctatggtt tcttctgagc tgactcagga ccctgcagtg
      121 tctgtggcct tggggcagac agtcaggatt acctgccaag gagacagcct cagaagctct
      181 tatgcaaact ggtaccaaca gaggccaggc caggcccctg tgctggtcgt ctatggtaac
      241 aactaccggc cctcagggat cccagagcga ttctctggct cctactcccg aaacacagct
      301 tccttgacca tcactggggc tcaggtggaa gatgaggctg actattactg tgactcctgg
      361 gacagcagcg gaacccaatt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003186             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14480:12563
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003186
VERSION     KCWK01003186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14480:12563"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68924.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          164 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccacgt
      241 tattcctgta ctactactcc gactcagaca agcagttggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag cagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003187             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:4788:10463
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003187
VERSION     KCWK01003187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:4788:10463"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68925.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          159 c          120 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaattttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagttggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacga tagtgctgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003188             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:27681:8305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003188
VERSION     KCWK01003188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:27681:8305"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68926.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       408..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           98 a          153 c          114 g          114 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcaacggt ggcatcactg
      181 ttgctaccta ccatatatat tggtaccaac agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat atctggactc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagtgg tgattatatc ttcggtggtg
      421 ggacccgtct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003189             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:6888:20071
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003189
VERSION     KCWK01003189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6888:20071"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68927.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           97 a          153 c          126 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agactccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gatccaacat cggaagaaat agtgtatcct ggtaccagaa gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagcgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta cattttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003190             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:6964:9538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003190
VERSION     KCWK01003190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6964:9538"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68928.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          164 c          124 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt ggtcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003191             390 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:9254:9854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003191
VERSION     KCWK01003191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 390)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 390)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..390
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:9254:9854"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..352
                     /note="immunoglobulin light chain variable region"
     V_region        28..352
     V_segment       28..314
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <277..>324
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68929.1"
                     /translation="DYYCQVWDTTLDHGLF"
     J_segment       316..352
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        353..>390
                     /gene="IGLC"
BASE COUNT           81 a          123 c          108 g           78 t
ORIGIN      
        1 acatgggact gcacaggctc tgcggcctcc tatgatctga ctcagccacc ctcggtgtca
       61 gtgtccccag gacagacggc caggatcacc tgtgggggag acaacattgg aagtcaaagt
      121 gtgcactggt accagcacaa gccaccgcag gcccctgttc tggtcatctt ttattatacc
      181 gaacggccct caggaatccc tgagcgattc tctggctcca aatcagggaa caccgccacc
      241 ctgaccatca gcggggtcga ggccggggat gaggctgact attactgtca ggtgtgggac
      301 acaactcttg atcacggctt attcggagga gggacccggc tgaccgtcct aggtcagccc
      361 aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003192             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:10906:7475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003192
VERSION     KCWK01003192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10906:7475"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..392
                     /note="immunoglobulin light chain variable region"
     V_region        76..392
     V_segment       76..362
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68930.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       363..392
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>432
                     /gene="IGLC"
BASE COUNT           84 a          135 c          116 g           97 t
ORIGIN      
        1 acatggggtg tctccaccat ggcctggact cctctctggc tcaccctcct cagtctttgc
       61 acaggttcta tggtttcttc tgagctgact caggaccctg cagtgtctgt ggccttggga
      121 cagacagtca ggattacctg ccaaggagac agcctcagaa gctcttatgc aagctggtac
      181 caacagaggc caggccaggc ccctgtgctg gtcgtctatg gtaacaacta tcggccctca
      241 gggatcccag agcgattctc tggctcctac tcacgaaaca cagcttcctt gaccatctct
      301 ggggctcagg tggaagatga ggctgactat tactgtgact cctgggacag cagcggaacc
      361 caattcggag gagggacccg gctgaccgtc ctgggtcagc ccaaggctgc cccctcggtc
      421 actctcttcc cg
//
LOCUS       KCWK01003193             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:9444:4579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003193
VERSION     KCWK01003193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9444:4579"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68931.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       414..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          164 c          124 g          108 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcct
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcactgac
      181 ctcagtgttg gtggtaaaaa catgtactgg taccagcaga agccaggaag cgctcccagg
      241 ttattgctgt attaccactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgccaa cacgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01003194             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:13029:4409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003194
VERSION     KCWK01003194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:13029:4409"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..443
                     /note="immunoglobulin light chain variable region"
     V_region        115..443
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68932.1"
                     /translation="DYYCAAWDDSLRGFIF"
     J_segment       411..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>483
                     /gene="IGLC"
BASE COUNT           91 a          156 c          127 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggttt catcttcggt
      421 gatgggaccc ggctcaccgt cctgggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003195             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:21526:16615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003195
VERSION     KCWK01003195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21526:16615"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68933.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       392..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          140 c          137 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ccctgcggcc tcctatgatc tgactcaggc
      121 accctcgatt tcagtgtccc ccggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 gtatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacatgaata gtcatcatct attattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003196             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:13046:2014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003196
VERSION     KCWK01003196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13046:2014"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68934.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          150 c          115 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccgactg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003197             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:24313:5052
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003197
VERSION     KCWK01003197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24313:5052"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68935.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          157 c          121 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catacactgg taccagcaga agtctgggag tcccccccgg tatcttctaa
      241 gatacaaatc agactcggat cagggccagg gctctggggt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acggggattt tacacgtctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtga ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003198             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:22111:3105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003198
VERSION     KCWK01003198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22111:3105"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..383
                     /gene="IGLV3-35"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68936.1"
                     /translation="DYYCGSWDNSDKRYIF"
     J_segment       387..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          139 c          123 g          107 t
ORIGIN      
        1 acatggaggg gctcagaagc agaactctgg gtcgtctcca ccatggcctg gacccctccc
       61 ctgctcatcc tcctcactct ctgcacaggt tccgtggttt cctctgggct gactcaggag
      121 cctgcattgt ctgtggcctt gggacataca gtcaggatga cctgccaagg agacagcctc
      181 aaaacctatt acgcaagctg gtatcagcag aagccaggcc aggtccctgt gctggtcatt
      241 tatggtaaca ccaataggcc ctcagggatc ccaggccgat tctctggctc ctggtcagga
      301 aactcaggtt ccttgaccat cactggggct caggtggaag atgaggctga ctattactgt
      361 ggctcctggg ataacagtga taagcgttac atcttcggtg atgggacccg gttcaccgtc
      421 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01003199             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:9326:8168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003199
VERSION     KCWK01003199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9326:8168"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..403
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68937.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       408..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          159 c          114 g          114 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagtcaga ctcagctgca acttgagcag tggcatcaat
      181 gttggttctt acaccatatt ctggtaccag cagaagccag ggagtcctcc ccggttcctt
      241 ctgtactact actcagactc aaataatcac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc caatgcaggg cttttactga tctctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccatgtgg cacagcagcg cttatgcctt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003200             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:23063:19970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003200
VERSION     KCWK01003200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23063:19970"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68938.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          138 c          136 g          104 t
ORIGIN      
        1 acatgggggt gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggaaag acggccagga tcacctgtgg gggagacaat
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tattgatcat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003201             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:20111:17618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003201
VERSION     KCWK01003201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20111:17618"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68939.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          160 c          125 g          105 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gccgcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcgtg atttatgagg tcaatcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggc ctccagcctg aggacgaggc
      361 tgattattac tgcagttcat atgcaggcag cgacactttc gtgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003202             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:15952:15628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003202
VERSION     KCWK01003202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:15952:15628"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68940.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          161 c          109 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatttc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003203             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:3283:7223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003203
VERSION     KCWK01003203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:3283:7223"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68941.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       390..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           85 a          139 c          137 g          101 t
ORIGIN      
        1 acatggggga ctttgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctttacaggc tctgtggcct cctatgagtt gcctcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtaata gtgtgcattg gtaccagcag aagccaccgc gggcccctgt attggtcatc
      241 tctgttgata gcgaacggcc ctcagggatc cctgggcgat tctctggttc cagatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg ataatattta taaatacgcg gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003204             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:21869:5452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003204
VERSION     KCWK01003204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21869:5452"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68942.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           82 a          163 c          124 g          102 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggc
      181 cactacagct acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggttcttg
      241 atgtggctta agagtgatgg cagccacacc aaggggggcg gggtccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatatt ggcatttggg tattcggcgg agggacccgg
      421 ctaatcgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003205             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:14342:13630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003205
VERSION     KCWK01003205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14342:13630"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68943.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          151 c          116 g          107 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggcccc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003206             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13990:3212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003206
VERSION     KCWK01003206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13990:3212"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68944.1"
                     /translation="DYYCQSADSSGNYPFF"
     J_segment       395..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          106 a          133 c          125 g           99 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaacact
      181 ggcaaaaaaa tatggtcagt ggttccagca gaagccaggc caggtccctg tgttggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga atctctagct ctagttcagg
      301 gacaacactt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagca gacagcagtg gaaattatcc gttcttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003207             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22417:5733
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003207
VERSION     KCWK01003207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22417:5733"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68945.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          106 a          135 c          121 g          101 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatactcagt ggttccagca gcagccaggc caggcccctt tcctggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagtt ccagttcagg
      301 gacaacaatt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagta gacagcagtg gaaatcttcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003208             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:21946:17626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003208
VERSION     KCWK01003208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21946:17626"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..446
                     /note="immunoglobulin light chain variable region"
     V_region        98..446
     V_segment       98..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68946.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           90 a          161 c          122 g          111 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt agtaaaaaca tgtactggta cctgcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caaataacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtatgacagt agtgctaatg tgttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01003209             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:9861:6096
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003209
VERSION     KCWK01003209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9861:6096"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68947.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       407..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          153 c          131 g          112 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgca
      181 ctgggaccag ctccaacatc ggggcgggtt tttgtgtttc ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atgtttgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattat tgttcatcat gggaaagcag cctgaattgg gtgttcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003210             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:5932:12072
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003210
VERSION     KCWK01003210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5932:12072"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68948.1"
                     /translation="DYYCSSYAGSYTFVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          159 c          124 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa cagcatccag ccacagcccc
      241 caaactcatg atttatgagg tcagtaagcg gccctcaggg atctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat atgcaggcag ctacactttc gtgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003211             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:26544:12275
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003211
VERSION     KCWK01003211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:26544:12275"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68949.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          141 c          137 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccagggtc acctgtgggg gagacaacat
      181 cggaggtgaa gttgtgaatt ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat ggcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccgga gatgaggctg actattactg
      361 tcaggtgtgg gaccttaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003212             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:2364:12748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003212
VERSION     KCWK01003212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:2364:12748"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..404
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68950.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          157 c          123 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccgc
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagtagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003213             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:17717:13725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003213
VERSION     KCWK01003213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17717:13725"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68951.1"
                     /translation="DFYCQSYDSNMSAQVF"
     J_segment       397..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          154 c          118 g          103 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag cagctccaac
      181 attgaacatt attatgtgca gtggtacctg cagcttccag gaacggcccc caaactcctc
      241 atctatcaaa ataataagcg accctcaggg atttctgatc gattctctgg ctcccagtct
      301 ggtagctcag cctccctgac catcactgga ctccagtctg aggacgaggc tgatttttac
      361 tgccagtcct atgacagcaa catgagtgct caggtgttcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003214             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:12419:21095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003214
VERSION     KCWK01003214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12419:21095"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68952.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          150 c          136 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcccctgtgg gggagacaac
      181 attggaacta aatatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
      241 atctatgctg ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg ggtatgaggc tgactatttc
      361 tgtcaggtgt gggacgatag tagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003215             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:6448:14453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003215
VERSION     KCWK01003215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:6448:14453"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68953.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           88 a          147 c          130 g           97 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct ccgatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtaaga gtgtgcactg gtaccagcac aagccaccgc aggcccctat cctggtcatc
      241 tattattata ccgaacggcc ctcggcgatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acactactat tgatcatggc tttttcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003216             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:8516:19515
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003216
VERSION     KCWK01003216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8516:19515"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68954.1"
                     /translation="DYYCQSADTSGNHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          108 a          135 c          122 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg aactgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagcaat
      181 actggaaaaa aaatatgctc agtggttcca gaagaagcca ggccaggccc ctatattggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gtttccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacacca gtggtaatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003217             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:19958:13812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003217
VERSION     KCWK01003217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19958:13812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68955.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          160 c          113 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt actgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcgtattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctggggtc cagtctgagg
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggtt caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003218             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:10306:3710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003218
VERSION     KCWK01003218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10306:3710"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68956.1"
                     /translation="DYFCQVWDSDSDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          150 c          133 g           96 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctctggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta catatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgcaggtc
      241 atctttgctg atagcaaacg gccctcaggg gtccctgacc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactatttc
      361 tgtcaggtgt gggacagtga tagtgatcat tacatcttcg gtgttgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003219             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:8136:19633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003219
VERSION     KCWK01003219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8136:19633"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68957.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          150 c          117 g          107 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggacgc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003220             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:4189:12325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003220
VERSION     KCWK01003220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:4189:12325"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..421
                     /note="immunoglobulin light chain variable region"
     V_region        91..421
     V_segment       91..377
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68958.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       391..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           86 a          150 c          115 g          108 t
ORIGIN      
        1 acatgggggc agcgctctca ggacttctcc accatggtct gggctctgct cctcctcacc
       61 ctcctcactc agggcacagg atcctgggct caggctgccc cgactcagac tccctctgtg
      121 tccgggtctc ctggacagtc ggtcaccatc tcctgcactg gaaccagcag tgatattggg
      181 tattatcatg ctgtgtcttg gtaccagcat catccaggca aagcccccaa actcatgatt
      241 tatgaggtca ataaacggcc cgcaggggtc tctgatcgct tctctggctc caagtctggc
      301 aacacggcct ccctgaccat ctctgggctc cagactgagg atgaggctga ttattactgt
      361 agctcatatg caggcagcaa cagtttattc ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003221             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:24035:16928
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003221
VERSION     KCWK01003221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24035:16928"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68959.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          155 c          119 g          107 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cggcggtggc atcaatgttg
      181 ctggctacca catacactgg taccaacaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt caccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtga ttacatcttc ggtgctggga
      421 cccgactcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003222             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:8582:4274
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003222
VERSION     KCWK01003222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8582:4274"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68960.1"
                     /translation="DYYCQVWDISTDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          144 c          133 g          101 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag cctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccagggt cacctgtgga ggagacaacc
      181 ttggatatga agttgtcaac tggtaccagc agaagccacc gcaggcccct gtggtggtca
      241 tctatgctga ttatgaacgg ccctcaggga tccctaaccg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcggag tcgaggccgg ggatgaggct gactattatt
      361 gtcaggtgtg ggacattagt actgaccatc cggtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003223             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:12881:17552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003223
VERSION     KCWK01003223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12881:17552"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68961.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          161 c          112 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcatcaat
      181 gttggtagtt acagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
      241 ctgtactact actcagactc aagtaaacac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatgcaggc cttttagtga tctctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccatatgg cacagcagcg cttcttactt cttcggtact
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003224             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:18220:18508
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003224
VERSION     KCWK01003224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18220:18508"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68962.1"
                     /translation="DYYCNSYGGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          152 c          121 g          112 t
ORIGIN      
        1 acatgggggc ttggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcaact catatggagg cagcaatagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003225             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:13673:18481
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003225
VERSION     KCWK01003225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13673:18481"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68963.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          158 c          128 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccggaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003226             338 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:4724:17171
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003226
VERSION     KCWK01003226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 338)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4724:17171"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..297
                     /note="immunoglobulin light chain variable region"
     V_region        5..297
     V_segment       5..262
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <228..>272
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68964.1"
                     /translation="DYYCQVWDSDSKWVF"
     J_segment       264..297
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>338
                     /gene="IGLC"
BASE COUNT           73 a          100 c          104 g           61 t
ORIGIN      
        1 acatggggtc agcggcctca ggacagacgg ccaggatcac ctgtggcggg gacagccttg
       61 gaacaaaata tgtgcactgg taccagcaga agccaacgca ggcccctgtg gtggtcatct
      121 atgctgataa taaacggccc tcagggatcc ctgagcgatt ctctggctcc aactcaggga
      181 acaccgccac cctgaccatc agcagggtcg aggccgggga tgaggctgac tattactgtc
      241 aggtgtggga cagtgatagt aagtgggtct tcggcggagg gacccggcta accgtcccag
      301 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003227             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:14842:13090
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003227
VERSION     KCWK01003227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14842:13090"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68965.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          136 c          139 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcaggc
      121 accctcgatt tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccagca gaaggcaccg caggcccctg tgttggtcat
      241 gtatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatgaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003228             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:21203:17814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003228
VERSION     KCWK01003228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21203:17814"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..388
                     /note="immunoglobulin light chain variable region"
     V_region        58..388
     V_segment       58..344
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <316..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68966.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       358..388
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           83 a          139 c          106 g           98 t
ORIGIN      
        1 acatgggggg ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag
       61 gctgccccga ctcagactcc ctctgtgtcc gggtctcctg gacagtcggt caccatctac
      121 tgcactggaa ccagcagtga tattgggtat tatcatgctg tgtcttggta ccaacatcat
      181 ccaggcaaag cccccaaact catgatttat gaggtcaata aacggcccgc aggggtctct
      241 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag
      301 actgaggatg aggctgacta ttactgcagc tcatatgcag gcagcaacag tttattcttc
      361 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      421 ttcccg
//
LOCUS       KCWK01003229             423 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16993:12454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003229
VERSION     KCWK01003229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16993:12454"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..385
                     /note="immunoglobulin light chain variable region"
     V_region        58..385
     V_segment       58..345
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <307..>357
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68967.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       349..385
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        386..>423
                     /gene="IGLC"
BASE COUNT           83 a          125 c          119 g           96 t
ORIGIN      
        1 acatggggga cttttctcct cctcggcctc cttgcttact gcacaggctc tgcggcctcc
       61 tatgatctga ctcagccacc ctcggtgtca gtgtccccag gaaagacggc caggatcacc
      121 tgtgggggag acaatattgg aagtgaagtt gtcaactggt accagcagaa gccaccgcag
      181 gcccctgtgg tggtcatcta tgctgattat gaacggccct cagggatccc tgagcgattc
      241 tctggctcca aatcagggaa cacggccacc ctgaccatca gcggagtcga ggccggggat
      301 gaggctgact attactgtca ggtttgggac atttatattg atcatccggt gttattcgga
      361 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      421 ccg
//
LOCUS       KCWK01003230             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:17055:9174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003230
VERSION     KCWK01003230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17055:9174"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68968.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       391..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          140 c          138 g           97 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactttac aggctctgcg gcctcctatg aactgactca
      121 gccacgctca gtgtccgtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt aaaagtgtgc agtggtacca gcagacgcca ccgcaggccc ctatactggt
      241 catttatggt gatagggaac ggccctcagg gatccctgag cgattctctg gctccaactc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggatagta gtagtaaata tgtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003231             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:24529:16223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003231
VERSION     KCWK01003231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:24529:16223"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68969.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          164 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggatgc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003232             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:14324:13104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003232
VERSION     KCWK01003232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14324:13104"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68970.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          157 c          117 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cgatatcttc
      241 tgagatacaa atcggactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003233             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:15420:10106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003233
VERSION     KCWK01003233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15420:10106"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..433
                     /note="immunoglobulin light chain variable region"
     V_region        85..433
     V_segment       85..394
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68971.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       396..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           95 a          150 c          110 g          116 t
ORIGIN      
        1 acatggggga aagaggctgt gtccaccatg gcctggactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctcgcagcct gtgctgactc agccaacctc cctctcagca
      121 tctcctggag catcagccag actcacctgc accttgaaca gtggcatcag tgttggtaat
      181 tacaggatat tctggtacca ccagaagcca gggagtcctc cccggtatct tctgaactac
      241 cacacagact cagatattca tcaggggtct ggagtcccca gccgcttctc tggatccaaa
      301 gatgcttcgg ccaatgcagg gattttactc atctctggac tccagtctga ggatgaggct
      361 gactattact gtatgatttg gcacaacaat gcttattggg ttttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003234             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:15182:20346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003234
VERSION     KCWK01003234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:15182:20346"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68972.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          140 c          137 g          103 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggttga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003235             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:24685:9426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003235
VERSION     KCWK01003235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:24685:9426"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..398
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68973.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       400..435
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           94 a          152 c          116 g          111 t
ORIGIN      
        1 acatggggtc tctggagcca gggatccctt ccaatatcag caccatggcc tggactctgc
       61 tcctcctcca gttcctcctc acttgctgcc cagggtccaa ttctcaggct gtagtgactc
      121 aggagccctc aatgactgtg tccccaggag ggacagtcac tctcacctgt gcttccagca
      181 ctggagcagt caccagtggt cactctccac actggttcca gcagaaacct ggacaagccc
      241 ccaagacact gatttataat acaaactaca gacactcctg gactcctgcc cggttctcag
      301 gctccctcct tgggggtaaa gctgccctga cactgtcagg tgcgcagcct gaggatgagg
      361 ctgagtatta ttgtttactg tactatagtg gtgctcagct gttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003236             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:7069:6216
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003236
VERSION     KCWK01003236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7069:6216"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..396
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68974.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       403..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           96 a          155 c          115 g          108 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcatctcctg gaacatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 ggctaccaca tatactggta ccaccagaag ccagggagtc ccccccggta tcttctgagg
      241 tacaaatcag actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagcgaacac agggatttta cacatctctg gactccagtc tgaggatgag
      361 gctgactatt actgtgccat tggacacagc agcggtgatt atatcttcgg tggtgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01003237             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17217:11101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003237
VERSION     KCWK01003237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17217:11101"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68975.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          149 c          139 g           91 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gggactgcga cctcctatga gctggctcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta actatgtgca ctggtaccag cagaagccag cgcaggcccc tgtagaggtc
      241 atctttgctg ataacaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggatcaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactatttc
      361 tgtcaggtgt ggggcagtcg tagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003238             277 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:24447:14103
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003238
VERSION     KCWK01003238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 277)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24447:14103"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..237
                     /note="immunoglobulin light chain variable region"
     V_region        10..237
     V_segment       10..203
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <167..>211
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68976.1"
                     /translation="DYYCCSRSTSSTYVF"
     J_segment       204..237
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>277
                     /gene="IGLC"
BASE COUNT           50 a           93 c           65 g           69 t
ORIGIN      
        1 acatgggtct gtctcctggt accaacaaca cccaggcaaa gcccccaaag tcatgatttt
       61 tggtgtcaat aatcggccct ctggggtctc tgaccgcttc tctggctcca agtctggcaa
      121 cacggcctcc ctgaccatct ctgggctcca gtctgaggac gaggctgatt attactgttg
      181 ttcacgttca accagtagca cttacgtctt cggtcctggg acccggctca ccgtcctggg
      241 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01003239             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:6707:15831
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003239
VERSION     KCWK01003239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6707:15831"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..378
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68977.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       380..416
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>433
                     /gene="IGLC"
BASE COUNT           88 a          133 c          123 g           89 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacttttc tcctcctcgg
       61 cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc caccctcggt
      121 gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca ttggaagtca
      181 aagtgtgcac tggtaccagc acaagccacc gcaggcccct gttctggtca tcttttatta
      241 taccgaacgg ccctcaggaa tccctgagcg aatctctggc tccaaatcag ggaacaccgc
      301 caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg
      361 ggacacaagt cttgatcacg gcttattcgg aggagggacc cggctgaccg tcctaggtca
      421 gcccaaggct gcc
//
LOCUS       KCWK01003240             294 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:21249:9980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003240
VERSION     KCWK01003240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 294)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21249:9980"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..256
                     /note="immunoglobulin light chain variable region"
     V_region        3..256
     V_segment       3..219
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <175..>228
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68978.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       220..256
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        257..>294
                     /gene="IGLC"
BASE COUNT           58 a           88 c           89 g           59 t
ORIGIN      
        1 acatggggga atgtatatgc ttactggttc cagcagaagc caggccaggc ccctgtagtg
       61 gtcatctaca aagataccaa ccggccctca gggatccctg agcgattctc tggctccgac
      121 tcagggaaca cggccaccct gaccatcagc agggtcgagg ctggggatga ggccgactat
      181 ttttgtgctg cagcctatgg cagtggcagc agctggcagt gggtattcgg cggagggacc
      241 cggctaatcg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003241             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:15068:9171
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003241
VERSION     KCWK01003241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15068:9171"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..450
                     /note="immunoglobulin light chain variable region"
     V_region        117..450
     V_segment       117..413
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68979.1"
                     /translation="DYYCQSYDSNLSAMLF"
     J_segment       415..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           90 a          155 c          128 g          115 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag tagttccaac ttcggggcgg gttattatgt gcactggtac cagcaacttc
      241 caggaacggc ccccaaactc ctcatctatg aaaacaatat gcgaccctca ggggtttctg
      301 atcgattctc tggctccaag tctggtacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag taatttgagt gctatgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01003242             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:11189:13957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003242
VERSION     KCWK01003242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11189:13957"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68980.1"
                     /translation="DYYCCSYTTSGTYIF"
     J_segment       399..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          158 c          119 g          112 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca gtggaaccag
      181 cagtgacgtt ggtggttata actctgtctc ctggtaccag cagcacccag gcaaagcccc
      241 caaactcatg atttatggtg tcagtcatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgttgttcgt atacaaccag tggcacttac atcttcgatg ttgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01003243             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:24693:7697
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003243
VERSION     KCWK01003243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24693:7697"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68981.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          156 c          128 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ctattatgat gatcagcgag cctcgggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003244             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:22393:11544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003244
VERSION     KCWK01003244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22393:11544"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..274
                     /note="immunoglobulin light chain variable region"
     V_region        8..274
     V_segment       8..237
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>246
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68982.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       238..274
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        275..>312
                     /gene="IGLC"
BASE COUNT           64 a           98 c           73 g           77 t
ORIGIN      
        1 acatgggtca atgttggtag ttacagcatc ttctggtacc agcagaagcc agggagtcct
       61 ccccggtacc ttctctacta ctactcagac tcaagtaaac accagggctc tggagtcccc
      121 agccgcttct ctggatccaa agatgcttcg gccaatgcag gccttttact gatctctggg
      181 ctccagtctg aagatgaggc tgactattac tgtgccatat ggcacagcag cgcttcttac
      241 ttcttcggaa ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      301 actctgttcc cg
//
LOCUS       KCWK01003245             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:16216:19952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003245
VERSION     KCWK01003245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16216:19952"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68983.1"
                     /translation="DYFCAAWDDSLTGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           94 a          158 c          120 g          110 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcctcctc accctcctca ctcactgtgc agggtccagg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaaccag ctccaacatc ggaagtaata gtgtatcctg gtaccagcag ctcccagaaa
      241 cgtctcccaa actcctcatc tattataatg atcggcgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttatttctgc gcagcatggg atgatagcct gaccggttac attttcggta
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01003246             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:21121:21060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003246
VERSION     KCWK01003246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21121:21060"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..268
                     /note="immunoglobulin light chain variable region"
     V_region        1..268
     V_segment       1..228
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>240
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68984.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       232..268
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        269..>306
                     /gene="IGLC"
BASE COUNT           64 a           87 c           90 g           65 t
ORIGIN      
        1 acatgggggg gagacaacat tggaagtgaa gttgtcaact ggtaccaaca gaagccaccg
       61 caggcccctg tggtggtcat ctatgctgat tatgaacggc cctcagggat ccctgaccga
      121 ttctctggct ccaaatcagg gaacacggcc accctgacca tcagcggagt cgcggccggg
      181 gatgaggctg actattactg tcaggtttgg gacatttata ctgatcatcc ggtgttgttc
      241 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      301 ttcccg
//
LOCUS       KCWK01003247             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:12385:20597
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003247
VERSION     KCWK01003247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12385:20597"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..446
                     /note="immunoglobulin light chain variable region"
     V_region        101..446
     V_segment       101..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68985.1"
                     /translation="DYHCQVYDGSAVLF"
     J_segment       413..446
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           87 a          161 c          123 g          113 t
ORIGIN      
        1 acatggggct gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagtagtga
      181 cctcagtgtt ggtagtaaaa acatgtactg gtaccagcag aagccaggga gcgctcccag
      241 gttattcctg tactacttct ccgactcaga caagcagttg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtaa cacagcgttt ttactcatct ctgggctcca
      361 gcctgaggac gaggccgatt atcactgtca ggtgtatgac ggtagtgctg ttttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01003248             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:8593:9225
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003248
VERSION     KCWK01003248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8593:9225"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68986.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          161 c          110 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtact gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc atcaatgttg
      181 gtagttacag cgtattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc taggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003249             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:7084:5518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003249
VERSION     KCWK01003249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7084:5518"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68987.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          143 c          132 g           93 t
ORIGIN      
        1 acatggggtg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag actctgcgac ctcctatgaa ctgactcagt
      121 caccctcagt gtcagcggcc tcgggacagc cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa aactgtgcac tggtaccagc agaagccacc gcagggccct gtattggtca
      241 tctttgctga tagtaaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003250             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:22447:2044
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003250
VERSION     KCWK01003250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:22447:2044"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68988.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       395..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           91 a          149 c          133 g           96 t
ORIGIN      
        1 acatggggct ggcttcagaa gcagcatctg ggacatgtca gccatggcct ggacgcctct
       61 cctcctcagc ctcctcgctc actgcacagg ctctgtggcc tcctatgagc tgactcagcc
      121 accctcagtg tcggtgtccc caggacagac agccagcatc acctgctctg gaaataaatt
      181 ggggaatgta tatgcttact ggttccagca gaagccaggc caggcccctg tagtggtcat
      241 ctacaaagat accaaccggc cctcagggat ccctgggcga ttctctggct ccgactcagg
      301 gaacacggcc accctgacca tcagcagggt cgaggctggg gatgaggccg actatttttg
      361 tgctgcagcc tatggcagtg gcagcagctg gcagtgggta ttcggcggag ggacccggct
      421 aatcgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003251             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:9213:9873
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003251
VERSION     KCWK01003251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9213:9873"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68989.1"
                     /translation="AYYCQVWDSDSDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          149 c          130 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaagccag cgcaggcccc tatgcaggtc
      241 atctatgctg atagcaaacg gccctcaggg atccctgaga gattctctgg ctccaactca
      301 ggaaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctattac
      361 tgtcaggtgt gggacagtga tagtgatcat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003252             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:16787:11804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003252
VERSION     KCWK01003252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:16787:11804"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..429
                     /note="immunoglobulin light chain variable region"
     V_region        84..429
     V_segment       84..392
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68990.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       393..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          159 c          107 g          110 t
ORIGIN      
        1 acatggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc ctgctcctct
       61 ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc ctctcagcat
      121 ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcaatgtt ggtagttaca
      181 gcatattctg gtaccagcag aagccaggga gtcctccccg gtaccttctt tactactact
      241 cagactcaag taaccaccag gactctggag tccccagccg cttctctgga tcgaaagatg
      301 cttcagccaa tgcagggctt ttactgatct ctgggctcca gtctgaagat gaggctgact
      361 attactgtgc cacatggcac agcagcgctt cttacatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01003253             366 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:20670:8327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003253
VERSION     KCWK01003253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 366)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:20670:8327"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    141..328
                     /note="immunoglobulin light chain variable region"
     V_region        141..328
     V_segment       141..288
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <256..>300
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68991.1"
                     /translation="DYYCGAWDSSLDYIF"
     J_segment       291..328
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        329..>366
                     /gene="IGLC"
BASE COUNT           63 a          123 c           96 g           84 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcatctat gacaataatc agcgaccctc agggatttct
      181 gaccgattct ctggctccag gtctggttcc tcagcctccc tgaccatcac tgggctccag
      241 cctggggatg aggctgatta ttactgcgga gcatgggata gcagcctgga ttacatcttc
      301 ggggctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      361 ttcccg
//
LOCUS       KCWK01003254             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:14433:19797
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003254
VERSION     KCWK01003254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14433:19797"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68992.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       409..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          153 c          129 g          113 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctctccttc tcactctgct ggttcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagcatctgg ggcccccggg cagagggtca ccatctcctg
      181 ctctgggagc agctccaaca tcggggcggg tttttatgtt tcctggtacc agcagttccc
      241 aggaacagcc cccaaactcc tcatctttga aaataataag cgaccctcag gggtttctga
      301 ccgattctct ggctccaagt ctggttcctc agcctccctg accatcactg gactccaatc
      361 tgaggatgag gctgattatt attgttcatc atgggaaagc agcctgaatt gggtattcgg
      421 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01003255             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:7064:10703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003255
VERSION     KCWK01003255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7064:10703"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68993.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          159 c          125 g          112 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga ggccagggag cgctcccagg
      241 ttattcctgt attactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaggtaac acagcgtttt tgctcatttc tggactccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtttgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01003256             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:4396:13766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003256
VERSION     KCWK01003256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:4396:13766"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..397
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68994.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           93 a          156 c          118 g          108 t
ORIGIN      
        1 acatgggggg gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccaa gcctatgctg actcagccgg cctccctctc
      121 agcatctcct ggagcatcag ccagtctcac atgcaccttc agcggtggca tcaatgttgc
      181 tgactaccac atacactggt accagcagaa gtcagggagt cctccccggt atcttctaag
      241 atacaaatca gactcagatc agggccaggg ctctggagtc cccagccgct tctctggatc
      301 caaagatgct tcagcgaaca cggggatttt acacgtctct gggctccagt ctgaggatga
      361 ggctgactat tactgtgcca ttgggcacag cagcggtgat tacatcttcg gtgctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003257             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20610:15209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003257
VERSION     KCWK01003257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20610:15209"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..439
                     /note="immunoglobulin light chain variable region"
     V_region        112..439
     V_segment       112..403
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68995.1"
                     /translation="DYYCQSHDTSLSVLF"
     J_segment       407..439
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           91 a          155 c          125 g          106 t
ORIGIN      
        1 acatgggggc ttcatctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tcgtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacacagc cgccctcagt gtctggggcc ccagggcaga gggtcagcat ctcctgcact
      181 gggagcagct ccaacattgg aggttattat gtatactggt accagcaggt cccaggaatg
      241 gcccccaaac tcctcatcta tgacaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggtgc ctcaggctcc ctgaccatca ctgggctcca gactgaggat
      361 gaggctgatt attactgcca gtcccatgac accagcctga gtgttctatt cggaggaggg
      421 acgcggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003258             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:18078:19039
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003258
VERSION     KCWK01003258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18078:19039"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68996.1"
                     /translation="DYYCQVWDTSIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          146 c          129 g           96 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtgag ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct atactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaagt attgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003259             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:25774:6646
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003259
VERSION     KCWK01003259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:25774:6646"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..416
                     /note="immunoglobulin light chain variable region"
     V_region        86..416
     V_segment       86..377
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68997.1"
                     /translation="DYYCGAWDSSLSGYIF"
     J_segment       379..416
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           86 a          150 c          113 g          105 t
ORIGIN      
        1 acatggggga cttgggacaa tcttcatcat gacctggtcc cctctcctcc tcacccttct
       61 cattcactgc acagggtcct gggcccagtc tgtcctgacg cagccgccct cagtgtctgc
      121 ggccccaggg cagaaggtca ccatctcctg ctctggaagt agctccaaca tcgggagaaa
      181 ttctgtctcc tggtaccagc aggtcccagg aacggccccc aaactcctca gctatgacaa
      241 tgataagcga ccctcagggg tttctgaccg attctctggc tccaagtctg gttcctcagc
      301 ctccctggcc atcactggac tccagactgg agatgaggct gattattact gcggagcatg
      361 ggatagcagt ctgagtggtt acattttcgg tgctgggacc cgactcaccg tcctaggtca
      421 gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01003260             397 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:9036:11000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003260
VERSION     KCWK01003260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 397)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9036:11000"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    29..359
                     /note="immunoglobulin light chain variable region"
     V_region        29..359
     V_segment       29..322
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68998.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       323..359
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>397
                     /gene="IGLC"
BASE COUNT           78 a          126 c          101 g           92 t
ORIGIN      
        1 acatgggcac tgtgcagggt cctgggccca gtctgtgttg actcagcctc cctcagcgtc
       61 tgaggccgcc gggaagagtg tcaccatctc ctgttctgga agcagctcca acatcggaag
      121 taatagtgta tcctggtacc aacaactccc agaaacggct cccaaactcc tcatgtatta
      181 taatcatcgg cgagcctcag gtgtctctga ccgattctct ggctccaagt ctggcccttc
      241 agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt actgcgcagt
      301 atgggatgat agcctgaccg gttacatctt cggtactggg acccggctca ccgtcctagg
      361 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01003261             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:11865:17296
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003261
VERSION     KCWK01003261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11865:17296"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV68999.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       416..450
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           92 a          154 c          128 g          114 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcacgatct
      181 cctgcagtgg gagcaactcc aacattggat attattatgt gcagtggtac cagcagcttc
      241 caggaacggc ccccaaactc ctcatctatg aaaataataa gcgaccctct ggggtttctg
      301 atcgattctc tggctcccag tctggtacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccact cctatgacag cagtttgagt ggtgtcttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01003262             390 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:12191:12226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003262
VERSION     KCWK01003262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 390)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 390)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..390
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12191:12226"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    22..352
                     /note="immunoglobulin light chain variable region"
     V_region        22..352
     V_segment       22..313
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <277..>324
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69000.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       318..352
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        353..>390
                     /gene="IGLC"
BASE COUNT           75 a          119 c          105 g           91 t
ORIGIN      
        1 acatgggcag ggtcctgggc ccagtctgtg ctgacgcagc cgccctcagt gtctggggcg
       61 cccgggcaga gggtcacgat ctcctgcagt gggagcaact ccaacattgg atattattat
      121 gtgcagtggt accagcagct tccaggaacg gcccccaaac tcctcatcta tgaaaataat
      181 aagcgaccct ctggggtttc tgatcgattc tctggctccc agtctggtac ctcagcctcc
      241 ctgaccatca ctggactcca gtctgaggat gaggctgatt attactgcca ctcctatgac
      301 agcagtttga gtggtgtctt attcggagga gggacccggc tgaccgtcct aggtcagccc
      361 aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003263             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16711:17767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003263
VERSION     KCWK01003263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16711:17767"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69001.1"
                     /translation="HYYCQVWDINSDHVLF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          141 c          132 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgat gttgtgaatt ggtaccacca gaagccaccg caggcccctg tactggtcat
      241 ctatgctaat accgatcggc cctcagggat ccctgagcga ttctctggct ccatatcagg
      301 gaacacggcc accctgacca tcaacggggt cgaggccggg gatgaggctc actattactg
      361 tcaggtgtgg gacattaata gtgatcatgt gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003264             453 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:11003:5150
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003264
VERSION     KCWK01003264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 453)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:11003:5150"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..415
                     /note="immunoglobulin light chain variable region"
     V_region        88..415
     V_segment       88..375
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69002.1"
                     /translation="DYYCDSWDTTGTHPVLF"
     J_segment       378..415
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>453
                     /gene="IGLC"
BASE COUNT           89 a          146 c          118 g          100 t
ORIGIN      
        1 tcagaagcag agctctgggg tgtctccacc atggcctgga ctcctctctg gctcaccctc
       61 ctcagtcttt gcacaggttc tgtggtttcc tctggcctga ctcaggaccc tgcagtgtct
      121 gtggccttgg gacagactgt caggatcacc tgccaaggag acagcctcag aaccagttat
      181 gcaagctggt accagcagaa gccaggccag gcccctgtcc tggtcgtcta tggtaacaac
      241 taccggccct cagggatccc agagcgattc tctggctcca actcaagaaa cacagcttcc
      301 ttgaccatca ctgggactca ggtggaagat gaggctgact attactgtga ctcctgggac
      361 accaccggta cccatcctgt gttattcgga ggagggaccc ggctgaccgt cctaggtcag
      421 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003265             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:7976:10982
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003265
VERSION     KCWK01003265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7976:10982"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69003.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          152 c          118 g          102 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagactccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagaa atagtgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagctgg ctccaggccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagcggt tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003266             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:16953:3019
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003266
VERSION     KCWK01003266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:16953:3019"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69004.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          161 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagtcac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003267             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14175:16368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003267
VERSION     KCWK01003267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14175:16368"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69005.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          143 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcaaccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003268             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:9175:3960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003268
VERSION     KCWK01003268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9175:3960"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..449
                     /note="immunoglobulin light chain variable region"
     V_region        116..449
     V_segment       116..412
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69006.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       413..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           83 a          169 c          129 g          106 t
ORIGIN      
        1 acatgggggc agtgtggctg cctcagcaga gccctgagga gtctgcacca tggcctggac
       61 cccaatcctc ctcctcctcc tcactctcct ccttcactgc acagggtctc tctcccagcc
      121 tgtgctgact cagtcgccct ctgcctctgc ctccctggga gcctcggtca agctcacctg
      181 cactctgagc agtggccact acagctacac catcgcatgg catcagcagc agcaagggaa
      241 ggcccctcgg ttcttgatgt ggcttaagag tgatggcagc cacaccaagg gggacggggt
      301 ccctgatcgc ttctcaggct ccagctccgg ggctgagcgc tacctcacca tctccaacct
      361 ccagtctgag gatgaggctg attattactg tcagacctgg gatattggca tttgggtttt
      421 cggcggaggg acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01003269             361 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:22710:19978
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003269
VERSION     KCWK01003269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 361)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22710:19978"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..323
                     /note="immunoglobulin light chain variable region"
     V_region        8..323
     V_segment       8..289
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <251..>295
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69007.1"
                     /translation="DYYCASYEGSNTFLF"
     J_segment       293..323
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        324..>361
                     /gene="IGLC"
BASE COUNT           72 a          116 c           91 g           82 t
ORIGIN      
        1 acatgggcag cctccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcag
       61 tggaaccagc agtaagattg ggtatcacaa tgctgtgtcc tggtaccaag agcatccagg
      121 caaagccccc aaactcatga tttatgacgt caataagcgg ccctcaggga tctctgatcg
      181 cttctctggc tccaagtctg gcgacacggc ctccctgacc atctctgggc tccagcctga
      241 tgatgagggt gattattact gcgcctcata tgaaggcagc aacactttcc tcttcggagg
      301 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      361 g
//
LOCUS       KCWK01003270             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20939:4662
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003270
VERSION     KCWK01003270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20939:4662"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69008.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          148 c          120 g          104 t
ORIGIN      
        1 acatgggggg tgggctcaga agcagaactc tgggtcctct ccaccatggc ctggacccct
       61 cccctgctca tcctcctcac tctctgcaca ggttccgtgg tttcctctga gctgactcag
      121 gagcctgcat tgtctgtggc cttgggacaa acagtcagga tgacctgcca aggagacagc
      181 ctcaaaacct attatgcaac ctggtaccag cagaagccag gccaggtccc tgtgctggtc
      241 atctatggta acaactaccg gccctcaggg atcccaggcc gattctctgt ctcctggtca
      301 ggaaacacag gttccttgac catcactgcg gctcaggtgg aagatgaggc tgactattac
      361 tgtaagtcct gggacagcag tggtacccat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003271             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:6313:11578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003271
VERSION     KCWK01003271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6313:11578"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69009.1"
                     /translation="DYYCLAWDTSLNWLF"
     J_segment       414..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          158 c          124 g          109 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccggaca gagggtcacc atctcctgca
      181 ttagcagcag ctccaacatc ggggcggctt attatgtgtc ctggtaccaa cagtacccag
      241 gaacagcccc caaactcctc atctttgaaa acaataagcg accttcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtccctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattac tgtttagcat gggataccag cctgaattgg ctcttcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003272             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:27090:7223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003272
VERSION     KCWK01003272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:27090:7223"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69010.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          161 c          121 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaaataaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003273             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:23711:5953
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003273
VERSION     KCWK01003273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23711:5953"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    176..379
                     /note="immunoglobulin light chain variable region"
     V_region        176..379
     V_segment       176..342
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>351
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69011.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       343..379
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        380..>417
                     /gene="IGLC"
BASE COUNT           73 a          136 c          112 g           96 t
ORIGIN      
        1 acatggggga agcgcagctt cagctgtggg tacagaaggc aggactcagg acaatctcca
       61 gcatggcctg gttccctctc gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc
      121 agtctgtgct gactcagcct ccctcagcgt ctgaggccgc caggaagagt gtctccatct
      181 cccaaactcc tcatctatta tagtgatcaa cgagcctcag gtgtctctga ccgattctct
      241 ggctctcagt ctggcacgtc agcctccctg gccatcagtg ggctccaggc cgaggatgag
      301 gctgattatt actgcgcagc atgggatgat agtctgagcg gttacatctt cggtgctggg
      361 acccggctcg ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01003274             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:12731:11562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003274
VERSION     KCWK01003274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12731:11562"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..444
                     /note="immunoglobulin light chain variable region"
     V_region        96..444
     V_segment       96..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69012.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       410..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          163 c          113 g          114 t
ORIGIN      
        1 acatggggcc cactgcaggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcccagcc tgtgctgacc cagccaacct
      121 ccctctcagc atctccggga gcatcagtca gactcagctg caccttgagc agtggcatca
      181 atgttggttc ttacaccata ttctggtacc agcagaagcc agggagtcct ccccggttcc
      241 ttctgtacta ctactcagac tcaaataatc accagggctc tggagtcccc agccgcttct
      301 ctggatccaa agatgcttca gccaatgcag ggcttttact gatctctggg ctccagtctg
      361 aagatgaggc tgactattac tgtgccatgt ggcacagcag cgcttatgcc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003275             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:15335:21559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003275
VERSION     KCWK01003275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15335:21559"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..392
                     /note="immunoglobulin light chain variable region"
     V_region        76..392
     V_segment       76..362
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69013.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       363..392
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>432
                     /gene="IGLC"
BASE COUNT           84 a          135 c          116 g           97 t
ORIGIN      
        1 acatggggtg tctccaccat ggcctggact cctctctggc tcaccctcct cagtctttgc
       61 acaggttcta tggtttcttc tgagctgact caggaccctg cagtgtctgt ggccttggga
      121 cagacagtca ggattacctg ccaaggagac agcctcagaa gctcttatgc aagctggtac
      181 caacagaggc caggccaggc ccctgtgctg gtcgtctatg gtaacaacta ccggccctca
      241 gggatcccag agcgattctc tggctcctac tcacgaaaca cagcttcctt gactatctct
      301 ggggctcagg tggaagatga ggctgactat tactgtgact cctgggacag cagcggaacc
      361 caattcggag gagggacccg gctgaccgtc ctgggtcagc ccaaggctgc cccctcggtc
      421 actctcttcc cg
//
LOCUS       KCWK01003276             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:5361:12877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003276
VERSION     KCWK01003276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5361:12877"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..268
                     /note="immunoglobulin light chain variable region"
     V_region        8..268
     V_segment       8..231
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <199..>240
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69014.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       232..268
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        269..>306
                     /gene="IGLC"
BASE COUNT           67 a           85 c           83 g           71 t
ORIGIN      
        1 acatggggtg ttggaaataa aaacatatac tggtaccagc agaagccagg gagcgctccc
       61 aggttattcc tgtactacta ctccgactca gacaagcagc tgggacctgg ggtccccaat
      121 cgagtctctg gctccaagga gacctcaagt catacagcgt ttttgctcat ttctgggctc
      181 cagcctgagg acgaggccga ttattactgt caggtgtatg acgatagtgc tgtgttattc
      241 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      301 ttcccg
//
LOCUS       KCWK01003277             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12718:4581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003277
VERSION     KCWK01003277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12718:4581"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69015.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          145 c          131 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctcttcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccag cagaagccac cacagggccc tgtattggtc
      241 atctttgctg acagtaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003278             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:13802:7737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003278
VERSION     KCWK01003278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13802:7737"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69016.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           96 a          157 c          124 g          107 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aagagtgtca ccatctcctg
      181 ttctggaagc agctccaaca tcggaagtaa taatgtgtcc tggtaccagc acctcccagg
      241 aacagctccc aaactcctca tctactataa tgatcaacga ggctcaggtg tctctgaccg
      301 attctctggc tccaagtctg gcacgtcagc ctccctggcc atcagtgggc tccagaccga
      361 ggatgaggct gattattact gcgcagcgtg ggatgataga ctgagcagtt acatcttcgc
      421 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01003279             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:23654:13125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003279
VERSION     KCWK01003279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23654:13125"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..431
                     /note="immunoglobulin light chain variable region"
     V_region        107..431
     V_segment       107..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69017.1"
                     /translation="DYYCQVWDSTSDHYIF"
     J_segment       394..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          153 c          132 g           96 t
ORIGIN      
        1 acatggggct gtctgggtct caggaggcag cattgacggt gcctcagcca tggcctggac
       61 ccttctcctc ctcggcctcc tcgctcactg cacaggctct gcgacctcct atgagctgac
      121 tcagccaccc tcggtgtcag cggcctcagg acagacggcc agggtcacct gtgggggaga
      181 caacattgga actacgtttg tgcactggta ccagcagaat ccaccgcagg cccctgtgca
      241 ggtcatcttt gcggataaca aacggccctc agggatccct gaacgattct ctggctccaa
      301 ctcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      361 ttactgtcag gtgtgggaca gtactagtga tcattacatc ttcggtggtg ggacccgcct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003280             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:7065:17846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003280
VERSION     KCWK01003280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7065:17846"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..431
                     /note="immunoglobulin light chain variable region"
     V_region        107..431
     V_segment       107..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69018.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       394..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          147 c          133 g           99 t
ORIGIN      
        1 acatggggct gtctgggtct caggaggcag cattgacggt gcctcagcca tggcctggac
       61 ccttctcctc ctcggcctcc tcgctcactg cacaggctct gcgacctcct ttgagctgac
      121 tcagccaccc tcggtgtcag tggcctcagg acagacggcc aggatcacct gtgggggaga
      181 caacattgga attaaatttg tccactggta ccagcagaag ccagcgcagg cccctgtgaa
      241 ggtcatctat gctgatgaca aacggccctc agggatccct gagagattct ctggctccaa
      301 ttcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      361 ttcctgtcag gtgtgggaca gtgagactga tcattacatc ttcggtgttg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003281             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:20152:4211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003281
VERSION     KCWK01003281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20152:4211"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69019.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          144 c          132 g           92 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctcttcgacc tcctatgaac tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa actgtgcact ggtaccagca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgac agtaaacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003282             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:10259:15870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003282
VERSION     KCWK01003282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10259:15870"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..296
                     /note="immunoglobulin light chain variable region"
     V_region        8..296
     V_segment       8..252
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69020.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       266..296
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>334
                     /gene="IGLC"
BASE COUNT           71 a           99 c           85 g           79 t
ORIGIN      
        1 acatggggga cagtcggtca ccatctcctg cactggaacc agcagtgata ttgggtatta
       61 tcatgctgtg tcttggtacc agcatcatcc aggcaaagcc cccaaactca tgatttatga
      121 ggtcaataaa cggcccgcag gggtctctga tcgcttctct ggctccaagt ctggcaacac
      181 ggcctccctg accatctctg ggctccagac tgaggatgag gctgattatt actgtagctc
      241 atatgcaggc agcaacagtt tattcttcgg aggagggacc cggctgaccg tcctaggtca
      301 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003283             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:14922:8645
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003283
VERSION     KCWK01003283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14922:8645"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..392
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69021.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       394..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           87 a          150 c          125 g          107 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctcctct
       61 cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc tgacgcagcc
      121 gccctcagtg tctggggcgc ccgggcagag ggtcaccatc tcctgcactg ggagcagctc
      181 caacattgga ggttattatg tgcagtggta ccagcagctt ccaggagcgg cccccaaact
      241 cctcatctat gaaaatgata aacgaccctc aggggtttct gatcgattct ctggctccca
      301 gtctgattcc tcagcctccc tgaccatcac tggactccag tctgaggatg aggctgatta
      361 ttactgccag tcctatgaca gcagcttgag tgttgtgtta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003284             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:24433:9375
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003284
VERSION     KCWK01003284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:24433:9375"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    53..382
                     /note="immunoglobulin light chain variable region"
     V_region        53..382
     V_segment       53..346
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <308..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69022.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       351..382
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>421
                     /gene="IGLC"
BASE COUNT           83 a          142 c          101 g           95 t
ORIGIN      
        1 acatggggtc ctcaccctcc tcactcactg tgcagttcca gggtcctggg cccagtctgt
       61 gctgactcag ccaccctcag cgtctgggac tcccgggcag agtgtcacca tctcgtgctc
      121 tggaagcagc tccaacattg gaactaatta tgtatactgg taccaacacc tcccaggaac
      181 ggcccccaaa ctcctcatct attatagtaa tcagcgaccc tcaggggtcc ctgaccgatt
      241 ctctggctct aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga
      301 tgaggctgat tattactgtg cagcatggga taacagcctg accagtccgg tattcggagg
      361 agggacccgg ctgaccgtcc taagtcagcc caaggctgcc ccctcggtca ctctcttccc
      421 g
//
LOCUS       KCWK01003285             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:11061:7682
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003285
VERSION     KCWK01003285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:11061:7682"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69023.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          155 c          127 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gcgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gttccaacat cggaagtcat agtgtatcct ggtatcagca gctcccagga
      241 acagctccca aactcctcat ctattatgat ggtcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003286             401 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:19863:7058
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003286
VERSION     KCWK01003286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 401)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19863:7058"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    39..363
                     /note="immunoglobulin light chain variable region"
     V_region        39..363
     V_segment       39..320
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <288..>335
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69024.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       329..363
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        364..>401
                     /gene="IGLC"
BASE COUNT           78 a          125 c          119 g           79 t
ORIGIN      
        1 acatggggct cctcgctcac tgcacaggct ctgcgacctc ctatgagctg gctcagccac
       61 cctcggtgtc agcggcctca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      121 gaagtaacta tgtgcactgg taccagcaga agccagcgca ggcccctgta gagattatct
      181 ttgctgataa caaacggccc tcagggatcc ctgagcgatt ctctggctcc aactcaggga
      241 tcaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tatttctgtc
      301 aggtgtgggg cagtcgtagt gatcatccgg tattcggcgg agggacccgg ctgaccgtcc
      361 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003287             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:14610:1956
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003287
VERSION     KCWK01003287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14610:1956"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69025.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          142 c          137 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggctccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003288             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:20857:7433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003288
VERSION     KCWK01003288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20857:7433"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..411
                     /note="immunoglobulin light chain variable region"
     V_region        81..411
     V_segment       81..372
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69026.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       374..411
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           82 a          144 c          117 g          106 t
ORIGIN      
        1 acatggggag gacagtctcc agcatggcct ggtctcctct cctcctcacc cttctcattc
       61 actgcacagg gtcctgggcc cagtctgtgc tgacgcagcc gccctcagtg tctggggcgc
      121 ccgggcagag ggtcaccatc tcctgcactg ggagcagctc caacattgga ggttattatg
      181 tgcagtggta ccagcagctt ccaggagcgg cccccaaact cctcatctat gaaaatgata
      241 aacgaccctc aggggtttct gatcgattct ctggctccca gtctgattcc tcagcctccc
      301 tgaccatcac tggactccag tctgaggatg aggctgatta ttactgccag tcctatgaca
      361 gcagcttgag tgttgtgtta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003289             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:17610:17976
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003289
VERSION     KCWK01003289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17610:17976"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69027.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           86 a          162 c          123 g          112 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc ttctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aaccagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta tttctgccag gtgtttgaca gtagtgttgt gttcttcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01003290             434 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:20811:20825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003290
VERSION     KCWK01003290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 434)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20811:20825"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..382
                     /note="immunoglobulin light chain variable region"
     V_region        63..382
     V_segment       63..357
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <324..>368
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69028.1"
                     /translation="DYYCQSFDSSGFWVF"
     J_segment       359..382
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>434
                     /gene="IGLC"
BASE COUNT           75 a          146 c          113 g          100 t
ORIGIN      
        1 acatgggggc ctgggctcca ctcctcctca ccctcctcgc tcactgcaca gggtcttggg
       61 ctgaggttgt gttcactcag ccccattctg tgtcggggtc tccggggcag acggtcacca
      121 tctcctgcac ccgcagcagt ggcagcattg acaacagcta tgtgtactgg taccagcagc
      181 ggccgggcag cgcccccacc actctgattt acaaagataa ccaaagaccc tctggggtcc
      241 ctgatcggtt ctctggctcc atcgacagct cctccaactc tgcctccctc accatctctg
      301 gactgaagtc tgaggacgag gcagactatt actgtcagtc ttttgacagc agcggttttt
      361 gggtgttcgg cggagggacc cgactaagtg tccttggtca gcccaaggct gccccctcgg
      421 tcactctctt cccg
//
LOCUS       KCWK01003291             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:13306:6613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003291
VERSION     KCWK01003291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13306:6613"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..446
                     /note="immunoglobulin light chain variable region"
     V_region        98..446
     V_segment       98..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69029.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           91 a          162 c          121 g          110 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt gttaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtc
      241 attcctatac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg gactccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtatgacagt agtgctaatg tgttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01003292             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:5614:3717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003292
VERSION     KCWK01003292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:5614:3717"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69030.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          161 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggta cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003293             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:12309:7165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003293
VERSION     KCWK01003293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12309:7165"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..443
                     /note="immunoglobulin light chain variable region"
     V_region        115..443
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69031.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>483
                     /gene="IGLC"
BASE COUNT           87 a          158 c          128 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctgggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003294             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17437:11584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003294
VERSION     KCWK01003294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17437:11584"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69032.1"
                     /translation="DYYCAAWDDSLSSLFF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          150 c          116 g          108 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtata ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctattata ataatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacttcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgacag cctgagcagt ttgttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003295             532 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:4587:9756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003295
VERSION     KCWK01003295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 532)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 532)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..532
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:4587:9756"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    170..494
                     /note="immunoglobulin light chain variable region"
     V_region        170..494
     V_segment       170..457
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <419..>466
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69033.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       459..494
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        495..>532
                     /gene="IGLC"
BASE COUNT          103 a          156 c          162 g          111 t
ORIGIN      
        1 acatgggggc tgatttgcat cacaggctgc gctctccagc agggggataa gaggcctggg
       61 aggaacctgc ccagcctggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg
      121 gacttttctc ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct
      181 gactcaggca ccctcgattt cagtgtcccc aggacagacg gccaggatca cctgtggggg
      241 agacaacatt ggaagtgaag ttgtgaactg gtaccagcag aaggcaccgc aggcccctgt
      301 gttggtcatg tatgctgata gcgagcggcc ctcagggatc cctgagcgat tctctggctc
      361 caaatcaggg aacacggcca ccctgaccat cagcggggtc gaggccgggg atgaggctga
      421 ctattattgt caggtgtggg acatgaatag tcatcatctg ttattcggag gagggacccg
      481 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003296             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:27510:18623
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003296
VERSION     KCWK01003296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:27510:18623"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..380
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69034.1"
                     /translation="DYYCQVWDSSSDHYIF"
     J_segment       390..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           88 a          148 c          130 g           95 t
ORIGIN      
        1 acatgggggt ctcaggaggc agcattgacg gtgcctcagc catggcctgg acccttctcc
       61 tcctcggcct cctcgctcac tgcacaggct ctgcgacctc ctatgagttg actcagccac
      121 cctcggtgtc agcggcctca ggacagacgg ccagggtcac ctgtggggga gacaacattg
      181 gaactacgtt tgtgcactgg taccagcaga atccaccgca ggcccctgtg cagctcatct
      241 ttgcggataa caaacggccc tcagggatcc ctgaacgatt ctctggctcc aactcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cagtagtagt gatcattata tcttcggtgg tgggacccgg ctcaccgtcc
      421 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01003297             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:18752:11128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003297
VERSION     KCWK01003297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18752:11128"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <170..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69035.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       215..251
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           56 a           88 c           87 g           58 t
ORIGIN      
        1 acatggggta tatgcttact ggttccagca gaagccaggc caggcccctg tagtggtcat
       61 ctacaaagat accaaccggc cctcagggat ccctgagcga ttctctggct ccgactcagg
      121 gaacacggcc accctgacca tcagcagggt cgaggctggg gatgaggccg actatttttg
      181 tgctgcagcc tatggcagtg gcagcagctg gcagtgggta ttcggcggag ggacccggct
      241 aatcgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003298             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:12936:4816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003298
VERSION     KCWK01003298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12936:4816"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..284
                     /note="immunoglobulin light chain variable region"
     V_region        7..284
     V_segment       7..252
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69036.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       253..284
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>322
                     /gene="IGLC"
BASE COUNT           72 a          101 c           89 g           60 t
ORIGIN      
        1 acatgggggg cagacagtca ggattacctg ccaaggagac agcctcagaa gctcttatgc
       61 aaactggtac caacagaggc caggccaggc ccctgtgctg gtcgtctatg gtaacaacta
      121 ccggccctca gggatcccag agcgattctc tggctcctac tcccgaaaca cagcttcctt
      181 gaccatcact ggggctcagg tggaagatga ggctgactat tactgtgact cctgggacag
      241 cagcggaacc caattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc
      301 cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003299             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18624:11423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003299
VERSION     KCWK01003299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18624:11423"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69037.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          161 c          122 g          110 t
ORIGIN      
        1 acatggggtg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaaataac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctgt attattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01003300             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:13914:8413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003300
VERSION     KCWK01003300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13914:8413"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69038.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          163 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 ccctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003301             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:10621:9444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003301
VERSION     KCWK01003301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:10621:9444"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69039.1"
                     /translation="DYYCQSADSSSHHYIF"
     J_segment       394..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT          105 a          134 c          120 g          106 t
ORIGIN      
        1 acatgggggt gtggttctag gaggaagagc tctgggtgtc tcaccatgac ctggaccact
       61 gttctgctcc cctttctcac tctctgcaca ggctctgagg cctcctatga actgacacag
      121 ccaccctcag tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagaaatg
      181 ctggaaaaaa aatatactca gtggttccag cggaagccag gccaggcccc tgttttggtg
      241 acctataaag acagtgagag gccctcaggg atccctgagc gattctctag ttccagttca
      301 gggacaacag ttaccttgac catcagtggg gcccaggcag aagatgaggc tgactattat
      361 tgtcaatcag cagacagtag tagtcatcat tatatcttcg gtcctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003302             354 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:24314:6249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003302
VERSION     KCWK01003302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 354)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24314:6249"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..316
                     /note="immunoglobulin light chain variable region"
     V_region        8..316
     V_segment       8..279
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <241..>288
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69040.1"
                     /translation="DYHCQVWDLNSHHLLF"
     J_segment       281..316
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        317..>354
                     /gene="IGLC"
BASE COUNT           73 a          103 c          107 g           71 t
ORIGIN      
        1 acatgggagc caccctcgat ttcagtgtcc ccaggacaga cggccagggt cacctgtggg
       61 ggagacaaca ttgggagtga agttgtgaac tggtaccagc agaagccacc gcaggcccct
      121 gtgttggtca tctatgctga tagcgagcgg ccctcaggga tccctgaacg attctctggc
      181 tccaaatcag ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct
      241 gactatcact gtcaggtgtg ggaccttaat agtcatcatt tgttattcgg aggagggacc
      301 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003303             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:9639:10491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003303
VERSION     KCWK01003303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:9639:10491"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69041.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           88 a          144 c          127 g          103 t
ORIGIN      
        1 actgggggct gtgggctcag gaggcagagc tctgggtgtc tcaccatggc ctggattcct
       61 ctcctactcc ccatcctcac tttctgcaca ggctctgcag cctcctatga gctgacacag
      121 ccaccctcgg tgtcagtgtc cccaggacag ccggccagga tcacctgctc tggagatgta
      181 ttgccaaaaa aatatgctta ttggttccag cagaagccag gccagtcccc tgtattggtc
      241 atctctgagg acaccgaacg gccctctggg atccctgaga gattctctgg ctccagctca
      301 gggacagtgg ccaccttgac tatcagtggg gcccaggtgg aggatgaagc tgactactac
      361 tgttactcag cagacagtag tggtcatggc ttcttcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003304             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:10368:9626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003304
VERSION     KCWK01003304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:10368:9626"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..396
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69042.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       398..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           95 a          150 c          116 g          110 t
ORIGIN      
        1 acatggggtc tggagccagg gatcccttcc aatatcagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcacctgtgc ttccagcact
      181 ggagcagtca ccagtggtca ctctccacac tggttccagc agaaacctgg acaagccccc
      241 aagacactga tttataatac aaactacaga cactcctgga ctcctgcccg gttctcaggc
      301 tccctccttg ggggtaaagc tgccctgaca ctgtcaggtg cgcagcctga ggatgaggct
      361 gagtattatt gtttactgta ctatagtggt gctcagctgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctaggtca ctctcttccc g
//
LOCUS       KCWK01003305             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:12472:11075
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003305
VERSION     KCWK01003305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:12472:11075"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..403
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69043.1"
                     /translation="DYHCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          162 c          113 g          107 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagtcagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacacacac tggtaccaac agaagccagg aagtcccccc cggtatcttc
      241 tgaaattcaa atcagacaca gaccagggcc aggggtctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggta ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctatcactgt gccattggtc acagcagcgg tccatacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003306             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:21955:17488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003306
VERSION     KCWK01003306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21955:17488"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69044.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          158 c          113 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003307             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:4122:12230
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003307
VERSION     KCWK01003307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4122:12230"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..430
                     /note="immunoglobulin light chain variable region"
     V_region        94..430
     V_segment       94..387
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69045.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       393..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          153 c          116 g          106 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gcatctgggg cccccgggca gagggtcacc atctcctgca ctgggagcag ctccaacatc
      181 ggggcgggtt attatgtatc ctggtaccag cagttcccag gaacagcccc caaactcctc
      241 atctatgaaa ataataaacg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggtacctcag cctccctgac catcactgga ctccaatctg aggatgaggc tgattattac
      361 tgctcagcat gggatagcag cctgagtatc aattacatct tcggttctgg gacccgtctc
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003308             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:17499:10977
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003308
VERSION     KCWK01003308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17499:10977"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69046.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           93 a          154 c          126 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtaacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatgatga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aggtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cggcatggga tgatagcctg agaggttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01003309             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:20330:2830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003309
VERSION     KCWK01003309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20330:2830"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69047.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       388..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           93 a          143 c          130 g           92 t
ORIGIN      
        1 acatgggggt ctcaggaggc agcattgacg gtgcctcagc catggcctgg acccttctcc
       61 tcctcggcct cctcgcttac tgcacagact ctgcgacctc ctatgaactg actcagtcac
      121 cctcagtgtc agcggcctcg ggacagccgg ccaggatcac ctgtggggga gacaacattg
      181 gaactaaaac tgtgcactgg taccagcaga agccaccgca gggccctgta ttggtcatct
      241 ttgctgatag taaacggccc tcagggatcc ctgagcgatt ctctggctcc aactcaggga
      301 acaccgccac cctgaccatc agcagggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cagtagtagt aaatggatat tcggcggggg gacccggcta accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003310             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:10161:8590
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003310
VERSION     KCWK01003310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10161:8590"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69048.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          163 c          122 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtggtaaaaa catgtactgg taccagcaga agccagggcg cgctcccagg
      241 tttttcctgt actacaattc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcac gtatatgaca gtagcactaa tgtgttattc
      421 ggaggaggga cccgtctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01003311             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:9177:11839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003311
VERSION     KCWK01003311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9177:11839"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69049.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       412..448
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          159 c          127 g          109 t
ORIGIN      
        1 acatggggag cgcagcttca gctgtgggta cagaaggcag gactcaggac aatctccagc
       61 atggcctggt tccctctcgt cctcaccctc ctcactcact gtgcagggtc ctgggcccag
      121 tctgtgctga ctcagcctcc ctcagcgtct gaggccgcca ggaagagtgt ctccatctcc
      181 tgttctggaa gcagctccaa catcggaagt catagtgtct cctggtacca gcagctccca
      241 ggaacagctc ccaaactcct catctattat agtgatcaac gagcctcagg tgtctctgac
      301 cgattctctg gctccaagtc tggcacgtca gcctccctgg ccatcagtgg gctccagacc
      361 gaggatgagg ctgattatta ctgcgcggca tgggatgata gcctgagcgg ttacatcttc
      421 ggtgctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      481 ttcccg
//
LOCUS       KCWK01003312             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:6676:11092
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003312
VERSION     KCWK01003312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:6676:11092"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..260
                     /note="immunoglobulin light chain variable region"
     V_region        4..260
     V_segment       4..223
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>232
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69050.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       224..260
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>298
                     /gene="IGLC"
BASE COUNT           67 a           94 c           72 g           65 t
ORIGIN      
        1 acatggggac cacatacact ggtaccagca gaagccaggg agtccccccc ggtatcttct
       61 gagttacaaa tcagactcag ataagggcca gggctctgga gtccccagcc gcttctctgg
      121 atccaaaaat gcttcaacaa acacaggcat tttacacatc tctgggctcc agtctgagga
      181 tgaggctgac tatttctgtg ccattggaca cagcagcggt ccttacatct tcggtgctgg
      241 gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01003313             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:11938:8138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003313
VERSION     KCWK01003313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11938:8138"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..422
                     /note="immunoglobulin light chain variable region"
     V_region        98..422
     V_segment       98..385
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69051.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       386..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          144 c          117 g          107 t
ORIGIN      
        1 acatgggggc tcagaagcag aactctgggt cctctccacc atggcctgga cccctcccct
       61 gctcatcctc ctcactctct gcacaggttc cgtggtttcc tctgagctga ctcaggagcc
      121 tgcattgtct gtggccttgg gacatacagt caggatgacc tgccaaggag acagcctcaa
      181 aacctattat gcaagctggt accagcagaa gccaggccag gtccctgtgt tggtcatcta
      241 tggtaacaac tatcggccct cagggatccc aggccgattc tctgtctcct ggtcaggaaa
      301 cacaggttcc ttgaccatca ctgcggctca ggtggaagat gaggctgact attactgtaa
      361 gtcctgggac agcagtggta cccattacat cttcggtgct gggacccggc tcaccgtcct
      421 aggtcagccc aaggtttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003314             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:14582:4817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003314
VERSION     KCWK01003314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14582:4817"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69052.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          162 c          116 g          108 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctctgcat ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctgcct accacataca ctggtaccag cagaagccag ggagtcctcc ccggtatctt
      241 ctgagataca aatcagactc agataaggac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcctcagc gaacacaggg attttacgca tctctgggct ccagtctgag
      361 gatgaggctg actactactg tgccattggg cacagcagcg gtgattacat cttcgctgct
      421 gggacccgcc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003315             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:18823:19494
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003315
VERSION     KCWK01003315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18823:19494"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69053.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       409..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          161 c          124 g          106 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctcgtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacaca gccgccctca gtgtctgggg ccccagggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaacatt ggaggttatt atatatcctg gtaccagcag ctcccaggaa
      241 cggcccccaa actcctcgtc tatgacaata ataagcgacc ctcaggggtt tctgaccgat
      301 tctctggctc caagtctggt tcctcagcca ccctgaccat cactgggctc cagactgagg
      361 atgaggctga ttattactgc cagtcctatg acagcagtct gagtgctcgg gtattcggcg
      421 gagggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003316             345 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12431:5862
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003316
VERSION     KCWK01003316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 345)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12431:5862"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    2..307
                     /note="immunoglobulin light chain variable region"
     V_region        2..307
     V_segment       2..270
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <232..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69054.1"
                     /translation="DYYCLEWHDSLSTGLF"
     J_segment       271..307
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>345
                     /gene="IGLC"
BASE COUNT           74 a          105 c           88 g           78 t
ORIGIN      
        1 acatgggggg cccccgggca gagggtcacc atctcctgca ctgggaacag ccccaatatc
       61 ggggcgaatt attatgtatc gtggtaccag catttcccag gaacagcccc caaactcctc
      121 atctatgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      181 ggtacctcag cctccctgac catcactggg ctccagtctg aggatgaggc tgattattac
      241 tgcttagaat ggcatgatag cctgagtact ggcttattcg gaggagggac ccggctgacc
      301 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003317             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:15846:12396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003317
VERSION     KCWK01003317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15846:12396"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..265
                     /note="immunoglobulin light chain variable region"
     V_region        1..265
     V_segment       1..228
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69055.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       231..265
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           61 a           90 c           92 g           60 t
ORIGIN      
        1 acatgggggg gagacaacat tggaactaac tatgtgcact ggtaccagca gaagccagcg
       61 caggcccctg tagaggtcat ctttgctgat aacaaacggc cctcagggat ccctgagcga
      121 ttctctggct ccaactcagg gatcaccgcc accctgacca tcagcggggt cgaggccggg
      181 gatgaggctg actatttctg tcaggtgtgg ggcagtcgta gtgatcatcc ggtattcggc
      241 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      301 ccg
//
LOCUS       KCWK01003318             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:21863:8811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003318
VERSION     KCWK01003318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21863:8811"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..440
                     /note="immunoglobulin light chain variable region"
     V_region        110..440
     V_segment       110..403
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69056.1"
                     /translation="DYFCAAWDDSLTGYIF"
     J_segment       404..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           91 a          158 c          120 g          109 t
ORIGIN      
        1 acatggggtt cagctgtggg tacagaaggc aggactcagg acaatctcca gcatggcctg
       61 gttccctctc ctcctcaccc tcctcactca ctgtgcaggg tccagggccc agtctgtgct
      121 gactcagcct ccctcagcgt ctgaggccgc caggaagagt gtcaccatct cctgttctgg
      181 aaccagctcc aacatcggaa gtaatagtgt gtcctggtac cagcagctcc cagaaacggc
      241 tcccaaactc ctcatctatt ataatcatcg gcgagcctca ggtgtctctg accgattctc
      301 tggctccaag tctggcacgt cagcctccct ggccatcagt gggctccaga ccgaggatga
      361 ggctgattat ttctgcgcag catgggatga tagcctgacc ggttacattt tcggtcctgg
      421 gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01003319             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:18949:2609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003319
VERSION     KCWK01003319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18949:2609"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69057.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          152 c          116 g          116 t
ORIGIN      
        1 acatgggggc tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgagcagt ggcttcagta
      181 ttggtaatta caggatattc tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagctacca cacagactca gatatgcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgtttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggta ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003320             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:21548:5573
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003320
VERSION     KCWK01003320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21548:5573"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69058.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          160 c          112 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta catcatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003321             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:24373:4622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003321
VERSION     KCWK01003321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:24373:4622"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..212
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69059.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       221..251
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           60 a           89 c           70 g           70 t
ORIGIN      
        1 acatgggggg gcggcttatt atgtatcctg gtaccaacag ttcccaggaa cagcccccaa
       61 actcctcatc tttgaaaata ataagcgacc ctcaggggtt tctgaccgat tctctggctc
      121 caagtctggt ccctcagcct ccctgaccat cactggactc caatctgagg atgaggctga
      181 ttattactgt ttagcatggg ataccagcct gaattggatc ttcggcggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003322             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:17722:3222
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003322
VERSION     KCWK01003322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17722:3222"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69060.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          142 c          131 g           94 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgaac tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaattaaa actgtacact ggtaccagca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgat agtaagcggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgatgctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003323             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:12473:15321
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003323
VERSION     KCWK01003323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12473:15321"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..426
                     /note="immunoglobulin light chain variable region"
     V_region        104..426
     V_segment       104..389
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69061.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       392..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          139 c          136 g          103 t
ORIGIN      
        1 acatggggct gactttggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactttacag gctctgtggc cttctatgag ttgcctcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa tagtgtgcat tggtaccagc agaagccacc gcgggcccct gtattggtca
      241 tctctgttga tagcgaacgg ccctcaggga tccctgagcg attctctggt tccagatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggataatatt tataaatacg cggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003324             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:14152:15033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003324
VERSION     KCWK01003324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14152:15033"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..404
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69062.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       406..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           85 a          162 c          123 g          111 t
ORIGIN      
        1 catggggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt agtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt tctgccaggt gtttgacagt agtgttgtgt tcttcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01003325             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:24586:12333
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003325
VERSION     KCWK01003325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:24586:12333"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..392
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69063.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           87 a          157 c          114 g          116 t
ORIGIN      
        1 acatggggct gggatctcag gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaagc tgccccgact
      121 cagcctccct ctgtgtccgg gtctcctgga cagtcggtca ccatctcctg cactggatcc
      181 atcagtgata ttgggtctta taatgctgtg tcttggtacc aacagcatcc aggcaaagcc
      241 ccccaactca taatttttga ggtcaataag cggccctcag gggtctctga tcgcttctct
      301 ggctccaagt ctgacaacac ggcctccctg accatctctg ggctccaggc tgaggatgag
      361 gctgattatt actgctgctc atatgtaggc agcaacactt acatcttcga tgttgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01003326             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:16652:16504
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003326
VERSION     KCWK01003326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16652:16504"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..213
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69064.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       218..251
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           55 a           94 c           75 g           65 t
ORIGIN      
        1 acatggggga agtcatagtg tctcctggta ccagcagctc ccaggaacag ctcccaaact
       61 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctccca
      121 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      181 ttactgcgca gcatgggacg atagcctgcg cggctatatc ttcggtgctg ggacccggct
      241 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003327             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:7124:9733
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003327
VERSION     KCWK01003327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7124:9733"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69065.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           90 a          161 c          121 g          109 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttgga aataaaaaca tatactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtcatac agcgtttttg ctcatttctg ggctccagcc
      361 tgaggacgag gccgactatt actgtcaggt gtatgacgat agtgctgtgt tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01003328             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:10244:20071
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003328
VERSION     KCWK01003328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10244:20071"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69066.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          163 c          122 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aaacagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta tttctgccag ctgtttgaca gtagtgttgt gttcttcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01003329             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:24392:20564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003329
VERSION     KCWK01003329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24392:20564"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69067.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          142 c          137 g          101 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cccgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003330             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:18471:19650
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003330
VERSION     KCWK01003330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:18471:19650"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69068.1"
                     /translation="DYSCQVWDSESDYYIF"
     J_segment       388..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          145 c          133 g           95 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctttgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaattaaa tttgtccact ggtaccagca gaagccagcg caggcccctg tgaaggtcat
      241 ctatgctgat gacaaacggc cctcagggat ccctgagaga ttctctggct ccaattcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattcctg
      361 tcaggtgtgg gacagtgaga gtgattatta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003331             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:19397:14434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003331
VERSION     KCWK01003331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19397:14434"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69069.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          159 c          126 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tcgggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca actcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct cccagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcggcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003332             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:9533:4413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003332
VERSION     KCWK01003332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:9533:4413"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..297
                     /note="immunoglobulin light chain variable region"
     V_region        8..297
     V_segment       8..260
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69070.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       261..297
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>335
                     /gene="IGLC"
BASE COUNT           73 a          104 c           83 g           75 t
ORIGIN      
        1 acatgggcag gaagagtgtc accatctcct gttctggaag cagctccaac atcggaagta
       61 ataatgtgtc ctggtaccag cacctcccag gaacagctcc caaactcctc atctactata
      121 atgatcaacg aggctcaggt gtctctgacc gattctctgg ctccaagtct ggcacgtcag
      181 cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac tgcgcagcgt
      241 gggatgatag actgagcagt tacatcttcg ctgctgggac ccggctcacc gtcctaggtc
      301 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003333             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:19613:9917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003333
VERSION     KCWK01003333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:19613:9917"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..440
                     /note="immunoglobulin light chain variable region"
     V_region        110..440
     V_segment       110..405
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69071.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       410..440
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           91 a          155 c          121 g          111 t
ORIGIN      
        1 acatggggag tgctgggatc tcaggaggca gcgctctcag gacttctcca ccatggtctg
       61 ggctctgctc ctcctcaccc tcctcactca gggcacagga tcctgggctc aggctgcccc
      121 gactcagact ccctctgtgt ccgggtctcc tggacagtcg gtcaccatct cctgcactgg
      181 aaccagcagt gatattgggt attatcatgc tgtgtcttgg taccaacatc atccaggcaa
      241 agcccccaaa ctcatgattt atgaggtcaa taaacggccc gcaggggtct ctgatcgctt
      301 ctctggctcc aagtctggca acacggcctc cctgaccatc tctgggctcc agactgagga
      361 tgaggctgat tattactgca gctcatatgc aggcagcaac actttattct tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003334             405 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:25109:10734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003334
VERSION     KCWK01003334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 405)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:25109:10734"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    37..367
                     /note="immunoglobulin light chain variable region"
     V_region        37..367
     V_segment       37..331
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <295..>339
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69072.1"
                     /translation="DYSCCSYRSGNTWLF"
     J_segment       332..367
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        368..>405
                     /gene="IGLC"
BASE COUNT           74 a          131 c          106 g           94 t
ORIGIN      
        1 acatgggtcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac tcagcctccc
       61 tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac cagcagtgac
      121 attggtggtt atgatggcgt ctcctggtac cagcagcact cagggacagc ccccagactc
      181 ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc tggctccaag
      241 tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga ggctgattat
      301 tcttgttgct catataggag tggaaacact tggctattcg gcggagggac ccggctgacc
      361 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003335             305 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:17875:18383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003335
VERSION     KCWK01003335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 305)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17875:18383"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    67..267
                     /note="immunoglobulin light chain variable region"
     V_region        67..267
     V_segment       67..230
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <192..>239
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69073.1"
                     /translation="DYYCQSSDSDVDHPLF"
     J_segment       237..267
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        268..>305
                     /gene="IGLC"
BASE COUNT           63 a           83 c           88 g           71 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tgtgttggtg atatataaag acatggagag gccctcgggg atccctgagc
      121 gattctctag ctccagttca gggacaacag ttaccttgac catcagtggg gcccaggcag
      181 aagatgaggc tgactattac tgtcaatcat cagacagcga tgttgatcat ccgttgttcg
      241 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      301 tcccg
//
LOCUS       KCWK01003336             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17205:9368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003336
VERSION     KCWK01003336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17205:9368"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..424
                     /note="immunoglobulin light chain variable region"
     V_region        101..424
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69074.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>463
                     /gene="IGLC"
BASE COUNT           89 a          147 c          130 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaagtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003337             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:14126:8070
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003337
VERSION     KCWK01003337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14126:8070"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69075.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          162 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003338             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:7946:11220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003338
VERSION     KCWK01003338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7946:11220"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69076.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          140 c          135 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 agcctcggtg tcagtgtccc cgggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaaa aatgtgcact ggtaccagca ggagccaccg caggcccctg tgttggtcat
      241 cttttatgat aacaaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacatcgcc accctgacca tcagcgaggc cgaggccggg gatgaggctg actattactg
      361 tcagctgtgg gacagtagtg ttgatcatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003339             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15411:10554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003339
VERSION     KCWK01003339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15411:10554"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69077.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       412..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           91 a          156 c          127 g          113 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccctctc
      181 ctgcactggg agcagctcca acattggaga ttattatgtg cagtggtacc agcagcttcc
      241 aggaacggcc cccaaactcc tcatctatga aaataataag cgaccctcag gggtttctga
      301 tcgattctct ggctcccagt ctggtacctc agcctccctg accatcactg gactccagtc
      361 tgacgatgag gctgattatt actgtcagtc ctatgatagc agcctgagtg ttgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01003340             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:18586:7061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003340
VERSION     KCWK01003340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18586:7061"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69078.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           95 a          156 c          120 g          109 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggtacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcagc ctccctcaac gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct
      181 ggaagcaact ccaacatcgg aagttataat gtgtcctggt accagcagct cccaggaaca
      241 gctcccaaac tcctcatcta ttataatgat caacgagcct caggtgtctc tgaccgattc
      301 tctggctcca agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat
      361 gaggctgatt attactgcgc agcatgggat gatagcctga gcggttacat cttcgctgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003341             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:4404:10170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003341
VERSION     KCWK01003341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:4404:10170"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..398
                     /note="immunoglobulin light chain variable region"
     V_region        80..398
     V_segment       80..366
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <329..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69079.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       367..398
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>436
                     /gene="IGLC"
BASE COUNT           85 a          137 c          119 g           95 t
ORIGIN      
        1 acatgggggg ggtgtctcca ccatggcctg gactcctctc tggctcaccc tcctcagtct
       61 ttgcacaggt tctatggttt cttctgagct gactcaggac cctgcagtgt ctgtggcctt
      121 ggggcagaca gtcaggatta cctgccaagg agacagcctc agaagctctt atgcaaactg
      181 gtaccaacag aggccaggcc aggcccctgt gctggtcgtc tatggtaaca actaccggcc
      241 ctcagggatc ccagagcgat tctctggctc ctactcccga aacacagctt ccttgaccat
      301 cactggggct caggtggaag atgaggctga ctattactgt gactcctggg acagcagcgg
      361 aacccaattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      421 ggtcactctc ttcccg
//
LOCUS       KCWK01003342             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:5835:8364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003342
VERSION     KCWK01003342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5835:8364"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..433
                     /note="immunoglobulin light chain variable region"
     V_region        104..433
     V_segment       104..397
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69080.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       402..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>472
                     /gene="IGLC"
BASE COUNT           95 a          157 c          115 g          105 t
ORIGIN      
        1 acatggggga cagaaggcag gactcaggat aatctccagc atggcctggt tccctctcgt
       61 cctcaccctc ctcactcact gtgcagttcc agggtcctgg gcccagtctg tgctgactca
      121 gccaccctca gcgtctggga ctcccgggca gagtgtcacc atctcgtgct ctggaagcag
      181 ctccaacatt ggaactaatt atgtatactg gtaccaacac ctcccaggaa cggcccccaa
      241 actcctcatc tattatagta atcagcgacc ctcaggggtc cctgaccgat tctctggctc
      301 taagtctggc acctcagcct ccctggccat cactggtctc cgatctgagg atgaggctga
      361 ttattactgt gcagcatggg ataacagcct gaccagtccg gtattcggag gagggacccg
      421 gctgaccgtc ctaagtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003343             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:14766:19790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003343
VERSION     KCWK01003343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14766:19790"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69081.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       417..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           93 a          159 c          125 g          108 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg acagagggtc accatctcct
      181 gcactagcag cagctccaac atcggggcgg cttattatgt atcctggtac caacagtccc
      241 caggaacagc ccccaaactc ctcgtctttg aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtccct cagcctccct gaccatcact ggactccaat
      361 ctgaggatga ggctgattat tactgtttag catgggatac cagcctgaat tggatcttcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003344             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:17150:7704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003344
VERSION     KCWK01003344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17150:7704"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69082.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          157 c          128 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccggca gctcccagga
      241 acagctccca aactcctcat ctattatgat ggtcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggccg tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgcgaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003345             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:24134:9011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003345
VERSION     KCWK01003345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24134:9011"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..428
                     /note="immunoglobulin light chain variable region"
     V_region        105..428
     V_segment       105..391
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69083.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       393..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           94 a          149 c          115 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggttagtga ctcaggagcc
      121 ctcaatgact gtgtccccag gagggacagt cactctcacc tgtgcttcca gcactggagc
      181 agtcaccagt ggtcactctc cacactggtt ccagcagaaa cctggacaag cccccaagac
      241 actgatttat aatacaaact acagacactc ctggactcct gcccggttct caggctccct
      301 ccttgggggt aaagctgccc tgacactgtc aggtgcgcag cctgaggatg aggctgagta
      361 ttattgttta ctgtactata gtggtgctca gctgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003346             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:16105:12211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003346
VERSION     KCWK01003346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:16105:12211"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..265
                     /note="immunoglobulin light chain variable region"
     V_region        8..265
     V_segment       8..228
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69084.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       230..265
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>304
                     /gene="IGLC"
BASE COUNT           67 a           90 c           86 g           61 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaagtca aagtgtgcac tggtaccagc acaagccacc
       61 gcaggcccct gttctggtca tcttttatta taccgaacgg ccctcaggaa tccctgagcg
      121 aatctctggc tccaaatcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggacacaagt cttgatcacg gcttatttgg
      241 aggagggacc cggctgaccg tcctaagtca gcccaaggct gccccctcgg tcactctctt
      301 cccg
//
LOCUS       KCWK01003347             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:14301:17974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003347
VERSION     KCWK01003347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14301:17974"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69085.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       391..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          149 c          135 g           92 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagc ctctgcgacc tcctatgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaag tatgtgcact ggtaccagca gaagccagcg caggcccctg tgttggtcat
      241 ctatgctgat accagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 aaacaccgcc accctgacca tcagcggggt cgaggccggg tatgaggctg actatttctg
      361 tcaggtgtgg gacgatagta gtgatcatcc ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003348             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:13698:16631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003348
VERSION     KCWK01003348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:13698:16631"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69086.1"
                     /translation="DYYCQSADSSSHHYIF"
     J_segment       392..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          105 a          133 c          119 g          106 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgaac tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatgct
      181 ggaaaaaaaa tatactcagt ggttccagcg gaagccaggc caggcccctg ttttggtgat
      241 ctataaagac agtgagaggc cctcagggat ccctgagcga ttctctagtt ccagttcagg
      301 gacaacagtt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattattg
      361 tcaatcagca gacagtagta gtcatcatta tatcttcggt cctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003349             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:24528:12500
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003349
VERSION     KCWK01003349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:24528:12500"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..428
                     /note="immunoglobulin light chain variable region"
     V_region        102..428
     V_segment       102..395
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69087.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       396..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>470
                     /gene="IGLC"
BASE COUNT           86 a          152 c          125 g          107 t
ORIGIN      
        1 acatgggggg ggtacagaag gcaggactca ggacaatctc cagcatggcc tggttccctc
       61 tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg ctgactcagc
      121 ctccctcagc gtctgaggcc gccaggaaga gtgtctccat ctcctgttct ggaagcagct
      181 ccaacatcgg aagtcatagt gtctcctggt accagcagct cccaggaaca gctcccaaac
      241 tcctcatcta ttatagtgat caacgagcct caggtgtctc tgaccgattc tctggctctc
      301 agtctggcac gtcagcctcc ctggccatca gtgggctcca ggccgaggat gaggctgatt
      361 attactgcgc agcatgggat gatagtctga gcggttacat cttcggtgct gggacccggc
      421 tcgccgtcgt aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003350             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:25254:16324
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003350
VERSION     KCWK01003350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:25254:16324"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69088.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>460
                     /gene="IGLC"
BASE COUNT           93 a          143 c          125 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaagatc acctgctctg gagatgcact
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 cgatgaggac accaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003351             403 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:13837:6191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003351
VERSION     KCWK01003351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 403)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13837:6191"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    208..365
                     /note="immunoglobulin light chain variable region"
     V_region        208..365
     V_segment       208..328
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <296..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69089.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       329..365
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>403
                     /gene="IGLC"
BASE COUNT           70 a          138 c           99 g           96 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt ccccaatcga gtctctggct ccaaggagac
      241 ctcaactaac acagcgtttt tgctcatctc tgggctccag cctgaggacg aggccgatta
      301 ttactgtcag gtgtttgaca gtagtgctgt gttattcgga ggagggaccc gactgaccgt
      361 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003352             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:13016:12341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003352
VERSION     KCWK01003352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13016:12341"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69090.1"
                     /translation="AYYCQVWDGDSDHYIF"
     J_segment       392..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           93 a          149 c          130 g           95 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca cagactctgc gacctcctat gagctgactc
      121 agccaccctc ggtgtcaacg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaac taattttgtg cactggtacc agcagaagcc agcgcaggcc cctatgcagg
      241 tcatctatgc tgataacaaa cggccctcag ggatccctga gagattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gagtcgaggc cggggatgag gctgcctatt
      361 actgtcaggt gtgggacggt gatagtgatc attacatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01003353             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:21447:19867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003353
VERSION     KCWK01003353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21447:19867"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69091.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          148 c          130 g           96 t
ORIGIN      
        1 acatgggggg gcctcgggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttcttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003354             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:5647:4681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003354
VERSION     KCWK01003354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:5647:4681"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69092.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          141 c          133 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacac
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcaggcat ccctgagcga ttctctggct ccaaatcagg
      301 gaacatggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccgactgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003355             340 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:21109:4453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003355
VERSION     KCWK01003355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 340)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21109:4453"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..302
                     /note="immunoglobulin light chain variable region"
     V_region        8..302
     V_segment       8..259
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>274
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69093.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       265..302
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        303..>340
                     /gene="IGLC"
BASE COUNT           75 a          105 c           80 g           80 t
ORIGIN      
        1 acatgggggg cagagggtca ccatctcctg cactgggagc agctccaaca tcggggcggg
       61 ttattatgta tcctggtacc agcagttccc aggaacagcc cccaaactcc tcatctatga
      121 aaataataaa cgaccctcag gggtttctga ccgattctct ggctccaagt ctggtacctc
      181 agcctccctg accatcactg gactccaatc tgaggatgag gctgattatt actgctcagc
      241 atgggatagc agcctgagta tcaattacat cttcggttct gggacccgtc tcaccgtcct
      301 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003356             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:13332:15073
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003356
VERSION     KCWK01003356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13332:15073"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69094.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          149 c          128 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtaca ctggtaccag cacaagccac cgcaggcccc tgttctgctc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttgttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003357             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:20825:13448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003357
VERSION     KCWK01003357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:20825:13448"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69095.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          155 c          117 g          115 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggttct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaagctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtcttatg atgctgtgtc ttggtaccaa cagcctccag gcaaagcccc
      241 ccaactcata atttttgagg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgctgctcat atgtaggcag caacacttac atcttcgatg ttgggacccg
      421 gctcaccgtc ctaggtcagt ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01003358             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:11258:11034
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003358
VERSION     KCWK01003358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11258:11034"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..391
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69096.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       392..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          154 c          121 g          105 t
ORIGIN      
        1 acatggggga cagaaggcag gactcaggac aatctccagc atggcctggt tccctctcgt
       61 cctcaccctc ctcactcact gtgcagggtc ctgggcccag tctgtgctga ctcagcctcc
      121 ctcagcgtct gaggccgccg ggaagagtgt ctccatctcc tgttctggaa gcagctccaa
      181 catcggaagt catagtgtct cctggtacca gcagctccca ggaacagctc ccaaactcct
      241 catctattat agtgatcaac gagcctcagg tgtctctgac cgattctctg gctctcagtc
      301 tggcacgtca gcctccctgg ccatcagtgg gctccagacc gaggatgagg ctgattatta
      361 ctgcgcagca tgggatgata gcctgagcgg ttacatcttc ggtgctggga cccggctcgc
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003359             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:21809:10172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003359
VERSION     KCWK01003359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21809:10172"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69097.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>460
                     /gene="IGLC"
BASE COUNT           94 a          142 c          124 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcattt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaagatc acctgctctg gagatgcact
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 cgatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003360             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:19844:6337
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003360
VERSION     KCWK01003360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19844:6337"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    57..381
                     /note="immunoglobulin light chain variable region"
     V_region        57..381
     V_segment       57..343
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>353
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69098.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       345..381
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        382..>419
                     /gene="IGLC"
BASE COUNT           83 a          135 c          112 g           89 t
ORIGIN      
        1 acatggggac ttttctcctc ctcggcctcc ttgcttactg cacaggctct gcggcctcct
       61 atgatctgac tcagccaccc tcggtgtcag tgtccccagg acagacggcc aggatcacct
      121 gtgggggaga caacattgga agtcaaagtg tgcactggta ccagcacaag ccaccgcagg
      181 cccctgtact ggtcatcttt tattataccg aacggccctc aggaatccct gagcgattct
      241 ctggctccaa atcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg
      301 aggctgacta ttactgtcag gtgtgggaca caactattga tcacggcttc ttcggaggag
      361 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003361             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:6587:7426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003361
VERSION     KCWK01003361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6587:7426"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69099.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       400..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          156 c          127 g          107 t
ORIGIN      
        1 acatgggggc tgtggctcag gaagcagagc ctggagcatc tccaccatgg cctgggctcc
       61 actcctcctc accctcctcg ctcactgcac agggtcttgg gctgaggttg tgttcactca
      121 gccccaatct gtgtcggggt ctccggggca gacggtcacc atctcctgca cccgcagcag
      181 tggcagcatt ggcaacagct atgtgtactg gttccagcag cggccgggca gcgtccccac
      241 tattgtgatt tacaaagatg accaaagacc ctctggggtc cctgatcggt tctctggctc
      301 catcgacagc tcctccaact ctgcctccct caccatctct ggactgaagt ctggggacga
      361 ggctgactat tactgtcagt cttttgacag cagcagtgtc ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003362             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:10976:6186
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003362
VERSION     KCWK01003362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10976:6186"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..391
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69100.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       393..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          149 c          116 g          108 t
ORIGIN      
        1 atggggggag ccagggatcc cttccaatat cagcaccatg gcctggactc tgctcctcct
       61 ccagttcctc ctcacttgct gcccagggtc caattctcag gctgtagtga ctcaggagcc
      121 ctcaatgact gtgtccccag gagggacagt cactctcacc tgtgcttcca gcactggagc
      181 agtcaccagt ggtcactctc cacactggtt ccagcagaaa cctggacaag cccccaagac
      241 actgatttat aatacaaact acagacactc ctggactcct gcccggttct caggctccct
      301 ccttgggggt aaagctgccc tgacactgtc aggtgcgcag cctgaggatg aggctgagta
      361 ttattgttta ctgtactata gtggtgctca gctgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003363             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:22430:7937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003363
VERSION     KCWK01003363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22430:7937"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..418
                     /note="immunoglobulin light chain variable region"
     V_region        101..418
     V_segment       101..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69101.1"
                     /translation="DYYCYSSDSNSKWLF"
     J_segment       390..418
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>460
                     /gene="IGLC"
BASE COUNT           97 a          141 c          124 g           98 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatagcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgaga tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaagaaa tatgcttatt ggttcccgca gaaggcaggc cagcccccta tggtgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttactcatca gacagcaata gtaaatggct attcgacgga gggacccggc tgaccgtcgt
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003364             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:17336:11945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003364
VERSION     KCWK01003364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17336:11945"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69102.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       396..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT          106 a          139 c          122 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaccac agctctgggt gtctcaccat gacctggacc
       61 actgttctgc tcccctttct cactctctgc acaggctctg aggcctccta tgagctgaca
      121 caggcaccct cagtgtcagt gtccccagga cagacggcca ggatcacctg ctctggagaa
      181 atactggcaa aaaaatatac tcagtggttc cagcagcagc caggccaggc ccctttcctg
      241 gtgatatata aagacagtga gaggccctca gggatccctg agcgattctc tagctccagt
      301 tcagggacaa caattacctt gaccatcagt ggggcccagg cagaagatga ggctgactat
      361 tactgtcaat cagtagacag cagtggaaat cttccgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003365             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:12303:21738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003365
VERSION     KCWK01003365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12303:21738"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69103.1"
                     /translation="DYYCGIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          157 c          118 g          108 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcacgggt ggcatcaatg
      181 ttgctgacta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt ggcattgggc acagcagcgg tgattacatc ttcgctgatg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003366             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20965:8529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003366
VERSION     KCWK01003366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20965:8529"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69104.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          143 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003367             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:17960:7754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003367
VERSION     KCWK01003367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17960:7754"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69105.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          154 c          122 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt attatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaagctc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003368             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:21968:12922
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003368
VERSION     KCWK01003368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21968:12922"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..380
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69106.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       392..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          146 c          132 g           98 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctccttt gagttgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaat taaatttgtc cactggtacc agcagaagcc agcgcaggcc cctgtgaagg
      241 tcatctatgc tgatgacaaa cggccctcag ggatccctga gagattctct ggctccaatt
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 cctgtcaggt gtgggacagt gagactgatt attacatctt cggtactggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01003369             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:8274:6173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003369
VERSION     KCWK01003369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8274:6173"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..434
                     /note="immunoglobulin light chain variable region"
     V_region        86..434
     V_segment       86..397
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69107.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       398..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           91 a          158 c          117 g          106 t
ORIGIN      
        1 acatggggga gaggtagccg tgtccaccat ggccctgact cctctcctcc tcctgctcct
       61 ctctcactgc acaggttccc tctcccagcc tgtgctgact cagccaccct ccctgtctgc
      121 atccccggga gcatcggcca gactcccctg caccctgagc agtgacctca gtgttggtac
      181 taaaaacatg tactggtacc tacagaagcc agggagcgct cccaggttat tcctgtacta
      241 ctactccgac tcagacaagc agctgggacc tggggtcccc aatcgagtct ctggctccaa
      301 ggagacctca aagaacacag cgtttttgct catctctggg ctccagcctg aggacgaggc
      361 cgattattac tgtcaggtgt atgacagtag tgctaatgtg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003370             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:6573:10358
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003370
VERSION     KCWK01003370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6573:10358"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..396
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69108.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       406..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           93 a          154 c          118 g          109 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcatctcctg gaacatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 ggctaccaca tacactggta ccagcagaag ccagggagtc ctccccgata tcttctgaga
      241 tacaaatcgg actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagcgaacgc agggatttta cgcatctctg ggctccagtc tgaggatgag
      361 gctgactatt actgtgccat tgggcacagc agcggtgatt atattttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01003371             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:23654:8040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003371
VERSION     KCWK01003371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:23654:8040"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69109.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          156 c          127 g          111 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtctcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc tcagtctggc acgtcagcct ccctggccat cagtgggctc caggccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagtct gagcggttac atcttcggtg
      421 ctgggacccg gctcgccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01003372             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:16292:13866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003372
VERSION     KCWK01003372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16292:13866"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69110.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          160 c          114 g          109 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggggggggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003373             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:24115:10439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003373
VERSION     KCWK01003373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:24115:10439"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69111.1"
                     /translation="DYYCHVYDSSSNVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          163 c          124 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcgtcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtggtaaaaa catgtactgg taccagcaga agccagggcg cgctcccagg
      241 tttttcctgt actacaactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc cgggctccag
      361 cctgaggacg aggccgatta ttactgtcac gtatatgaca gtagtagtaa tgtgttattc
      421 ggaggaggga cccgtctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01003374             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:13474:6987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003374
VERSION     KCWK01003374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:13474:6987"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69112.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          149 c          116 g          109 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggttg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003375             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:13084:7514
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003375
VERSION     KCWK01003375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13084:7514"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69113.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          160 c          117 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctctgcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacat tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatataa atcagactca gataaggacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcctcagcg aacacggggc ttttgcacat ctctgggctc cagtctgagg
      361 atgaggctga ctactactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccgcct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003376             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:21406:15620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003376
VERSION     KCWK01003376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21406:15620"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69114.1"
                     /translation="AYYCQVWDSDSDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          148 c          130 g           96 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaagtcag cgcaggcccc tatgcaggtc
      241 atctatgctg atgtcaaacg gccctcaggg atccctgaga gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctattac
      361 tgtcaggtgt gggacagtga tagtgatcat tacatcttcg gtactgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003377             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:17134:11385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003377
VERSION     KCWK01003377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17134:11385"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69115.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       399..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           94 a          152 c          116 g          110 t
ORIGIN      
        1 acatggggct ctggagccag ggatcccttc caatatcagc accatggcct ggactctgct
       61 cctcctccag ttcctcctca cttgctgccc agggtccaat tctcaggctg tagtgactca
      121 ggagccctca atgactgtgt ccccaggagg gacagtcact ctcacctgtg cttccagcac
      181 tggagcagtc accagtggtc actctccaca ctggttccag cagaaacctg gacaagcccc
      241 caagacactg atttataata caaactacag acactcctgg actcctgccc ggttctcagg
      301 ctccctcctt gggggtaaag ctgccctgac actgtcaggt gcgcagcctg aggatgaggc
      361 tgagtattat tgtttactgt actatagtgg tgctcagctg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003378             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:6815:10464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003378
VERSION     KCWK01003378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6815:10464"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69116.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       400..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          154 c          128 g          101 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcgtctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttctgt tcacgcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgtaccc gcagcagagg
      181 caacattgac aatagttatg tgcagtggta ccagcagcgc ccggggagtg ccccgaccac
      241 agtgatttac agagataacc aaagagcctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctggg ctgaagtctg aggacgaggc
      361 tgactactac tgtcagtcta ctgatggcaa ctacaatagg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003379             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:8226:9427
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003379
VERSION     KCWK01003379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:8226:9427"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69117.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          148 c          133 g           96 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctccgatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa gagtgtgcac tggtaccagc acaagccacc gcaggcccct gtgctggtca
      241 tctattatta taccgaacgg ccctcggcga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcaccgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacactact attgatcatg gcttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003380             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:14916:13475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003380
VERSION     KCWK01003380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:14916:13475"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..439
                     /note="immunoglobulin light chain variable region"
     V_region        94..439
     V_segment       94..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69118.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       403..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           93 a          160 c          114 g          110 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcaatgtt
      181 ggtagttaca gcatattctg gtaccagcag aagccaggga gtcctccccg gtaccttctt
      241 tactattact cagactcaag taaccaccag gactctggag tccccagccg cttctctgga
      301 tcgaaagatg cttcagccaa tgcaggcctt ttactgatct ctgggctcca gtctgaagat
      361 gaggctgact attactgtgc cacatggcac agcagcgctt cttacatctt cggggggggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01003381             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:8264:12650
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003381
VERSION     KCWK01003381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8264:12650"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..402
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69119.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           82 a          158 c          129 g          107 t
ORIGIN      
        1 acatgggggg ctggggtctc aggaggcagc gctctcggga cgtctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag tctgccctga
      121 ctcagcctcc ctcagtgtcc aagtctcttg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga cattggtggt tatgatggcg tctcctggta ccagcagcac tcagggacag
      241 cccccagact cctgatttat gatgtcacta agcggccctc aggggtctcg gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tcaccatctc tgggctccag actgaggacg
      361 aggctgatta ttactgttgc tcatatagga gtggaaacac ttggctattc ggcggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003382             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:23842:14230
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003382
VERSION     KCWK01003382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:23842:14230"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69120.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           91 a          154 c          121 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctact gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgactat tactgcagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003383             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:21719:13402
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003383
VERSION     KCWK01003383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21719:13402"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69121.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          141 c          136 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccagggtc acctgtgggg gagacaacat
      181 cggaggtgaa gttgtgaatt ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccgga gatgaggctg actattactg
      361 tcaggtgtgg gaccttaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003384             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:29651:14420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003384
VERSION     KCWK01003384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:29651:14420"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    50..371
                     /note="immunoglobulin light chain variable region"
     V_region        50..371
     V_segment       50..337
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <299..>346
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69122.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       340..371
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        372..>412
                     /gene="IGLC"
BASE COUNT           82 a          130 c          116 g           84 t
ORIGIN      
        1 acatgggctc ctcctcggcc tccttgctta ctgcacagac tctgcggcct cctatgatct
       61 gactcagcca ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg
      121 agacaacatt ggaagtgaag ttgtgaactg gtaccagcag aagccaccgc aggcccctgt
      181 cctggtcatc tatgctaata acgaacggcc ctcagggatc cctgagcgat tctctggctc
      241 caaatcaggg aacacggcca ccctgaccat cagcggggtc gaggccgggg atgaggctga
      301 ctattactgt caggtgtggg gcgttactag tgatcatccc ttattcggag gagggacccg
      361 gctgaccgtc caaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003385             311 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:23523:7450
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003385
VERSION     KCWK01003385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 311)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 311)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..311
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23523:7450"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..273
                     /note="immunoglobulin light chain variable region"
     V_region        7..273
     V_segment       7..238
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <201..>245
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69123.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       243..273
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        274..>311
                     /gene="IGLC"
BASE COUNT           68 a           93 c           77 g           73 t
ORIGIN      
        1 acatgggcag tggaaccagc agtgatattg ggtattatca tgctgtgtct tggtaccaac
       61 atcgtccagg caaagccccc aaactcatga tttatgaggt caataaacgg cccgcagggg
      121 tctctgatcg cttctctggc tccaagtctg gcaacacggc ctccctgacc atctctgggc
      181 tccagactga ggatgaagct gattattact gcagctcata tgcaggcagc aacactttat
      241 tcttcggacg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      301 ctctcttccc g
//
LOCUS       KCWK01003386             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:21433:4778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003386
VERSION     KCWK01003386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21433:4778"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..395
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69124.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       399..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           86 a          156 c          124 g          104 t
ORIGIN      
        1 acatgggggg tggctcagga agcagagcct ggagcatctc caccatggcc tgggctccac
       61 tcctcctcac cctcctcgct cactgcacag ggtcttgggc tgaggttgtg ttcactcagc
      121 cccattctgt gtcggggtct ccggggcaga cggtcaccat ctcctgcacc cgcagcagtg
      181 gcagcattga caacggcttt gtgtactggt accagcagcg gccgggcagc gctcccacca
      241 ctgtgattta caaagataac caaagaccct ctggggtccc tgatcggttc tctggctcca
      301 tcgacagctc ctccaactct gcctccctca ccatctctgg actgaaatct gaggacgagg
      361 ctgactatta ctgtcagtct tatgacagca gcagtgtatt attcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003387             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:8874:15393
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003387
VERSION     KCWK01003387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8874:15393"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69125.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       392..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          139 c          141 g           97 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgc ggcctcctat gaggtgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taaaagtgtg cagtggtacc agcagacgcc accgcaggcc cctgtactgg
      241 tcatttatgg tgatagggaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggatagt agtagtaaat atgtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003388             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:2657:14694
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003388
VERSION     KCWK01003388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:2657:14694"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69126.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       414..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           93 a          161 c          125 g          108 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctcg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acacagccgc cctcagtgtc tggggcccca gggcagaggg tcaccatctc
      181 ctgcactggg agcagctcca acattggagg ttattatata tcctggtacc agcagctccc
      241 aggaacggcc cccaaactcc tcgtctatga caataataag cgaccctcag gggtttctga
      301 ccgattctct ggctccaagt ctggttcctc agccaccctg accatcactg ggctccagac
      361 tgaggatgag gctgattatt actgtcagtc ctatgacagc agtctgagtg ctcgggtatt
      421 cggcggaggg acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01003389             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:12369:18476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003389
VERSION     KCWK01003389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:12369:18476"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69127.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          150 c          115 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccagctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003390             285 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:23034:7400
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003390
VERSION     KCWK01003390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 285)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23034:7400"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..246
                     /note="immunoglobulin light chain variable region"
     V_region        11..246
     V_segment       11..206
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <168..>218
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69128.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       210..246
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        247..>285
                     /gene="IGLC"
BASE COUNT           56 a           85 c           82 g           62 t
ORIGIN      
        1 acatgggagt tgtcaactgg taccaacaga agccaccgca ggcccctgtg gtggtcatct
       61 atgctgatta tgaacggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      121 acacggccac cctgaccatc agcggagtcg cggccgggga tgaggctgac tattactgtc
      181 aggtttggga catttatact gatcatccgg tgttgttcgg aggagggacc cggctgaccg
      241 tcctaggtca gcccaaggct gcccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003391             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:18387:14304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003391
VERSION     KCWK01003391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18387:14304"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..450
                     /note="immunoglobulin light chain variable region"
     V_region        114..450
     V_segment       114..407
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69129.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       413..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           95 a          158 c          123 g          112 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaacatc ggggcgggtt attatgtatc ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaaa ataataaacg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattac tgctcagcat gggatagcag cctgagtatc aattacatct
      421 tcggttctgg gacccgtctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCWK01003392             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:5162:11284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003392
VERSION     KCWK01003392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:5162:11284"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69130.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          156 c          122 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaataa tgtgtcctgg taccagcacc tcccaggaac
      241 agctcccaaa ctcctcatct attataatga tcaacgaggc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcgtggga tgatagcctg agcagttaca tcttcgctgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01003393             318 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11510:6606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003393
VERSION     KCWK01003393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 318)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11510:6606"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..280
                     /note="immunoglobulin light chain variable region"
     V_region        7..280
     V_segment       7..241
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>252
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69131.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       243..280
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        281..>318
                     /gene="IGLC"
BASE COUNT           66 a           94 c           84 g           74 t
ORIGIN      
        1 acatggggtg gcatcaatgt tgctgtctac cacatacact ggtaccagca gaagccaggg
       61 agtccccccc ggtatcttct gaggtacaaa tcagactcag ataagggcca gggctctgga
      121 gtccccagcc gcttctctgg atccagtaat gcttcagcga acacagggat tttacgcatt
      181 tctgggctcc agtctgagga tgaggctgac tattactgtg ccattggaca cagcagcggt
      241 ctttacatct tcggtgctgg gacccggctc agcgtcctag gtcagcccaa ggcttccccc
      301 acggtcactc tgttcccg
//
LOCUS       KCWK01003394             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:19354:5417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003394
VERSION     KCWK01003394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:19354:5417"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69132.1"
                     /translation="DYYCQSHDTSSVFF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           84 a          164 c          125 g          109 t
ORIGIN      
        1 acatgggatt cattcctggc tgtggctcag gaagcagagc ctggagcatc tccaccatgg
       61 cctgggctcc actcctcctc accctcctcg ctcactgcac agggtcttgg gctgaggttg
      121 tgttcactca gccccattct gtgtcggggt ctccggggca gacggtcacc atctcctgca
      181 cccgcagcag tggcagcatt gacaacagtt ttgtgtactg gtaccagcag cggccgggca
      241 gcgcccccac cactgtgatt tacgcagata accaaagacc ctctggggtc cctgatcggt
      301 tctctggctc catcgacagc tcctccaact ctgcctccct caccatctct ggactgaagt
      361 ctgaggacga ggctgactac tactgtcagt ctcatgacac cagcagtgtg tttttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003395             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:7855:9284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003395
VERSION     KCWK01003395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:7855:9284"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69133.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           84 a          154 c          125 g          106 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccgggaagag tgtctccatc tcctgttctg gaagcagctc
      181 caacatcgga agtcatagtg tctcctggta ccagcagctc ccaggaacag ctcccaaact
      241 cctcgtctat tatagtgatc aacgagcctc tggtgtctct gaccgattct ctggcgctca
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcatgggatg atagcctgag cggttacatc ttcggtgctg ggacccggct
      421 cgccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003396             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:20864:20817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003396
VERSION     KCWK01003396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20864:20817"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..387
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69134.1"
                     /translation="DYYCSSYEGINTLVF"
     J_segment       408..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           86 a          156 c          120 g          114 t
ORIGIN      
        1 acatggggtg ctgggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccccga
      121 ctcagcctcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccaccagtga tattggatat tataatgctg tgtcttggta ccaacagcat ctaggcaaag
      241 cccccaaact cataatttat gaggtcactg agcggccctc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tggcctccag gctgaggatg
      361 agtctgatta ttactgcagc tcatatgagg gcatcaacac tttggttttc ggcggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003397             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:8108:4741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003397
VERSION     KCWK01003397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8108:4741"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69135.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          157 c          118 g          111 t
ORIGIN      
        1 acatggggca ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggaac atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gtttttggct accacataca ctggtaccag cagaagccag ggagtcctcc ccggtatctt
      241 ctgagataca aatcggactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc gaacgcaggg attttacgca tctctggact ccagtctgag
      361 gatgaggctg actattactg tgccattggg cacagcagcg gtgattacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003398             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:25490:8452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003398
VERSION     KCWK01003398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:25490:8452"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..439
                     /note="immunoglobulin light chain variable region"
     V_region        94..439
     V_segment       94..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69136.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       403..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           93 a          160 c          113 g          111 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcaatgtt
      181 ggtagttaca gcatattctg gtaccagcag aagccaggga gtcctccccg gtaccttctt
      241 tactactact cagactcaag taaccaccag gactctggag tccccagccg cttctctgga
      301 tcgaaagatg cttcagccaa tgcagggctt ttactgatct ctgggctcca gtctgaagat
      361 gaggctgact attactgtgc cacatggcac agcagcgctt cttacatctt cggtggtggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01003399             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:5574:11280
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003399
VERSION     KCWK01003399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5574:11280"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69137.1"
                     /translation="DYYCQVFDDSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          158 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagacgtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagaagaa ggcagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gttcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacga tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003400             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:12072:12148
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003400
VERSION     KCWK01003400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12072:12148"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69138.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          148 c          129 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtacac tggtaccagc acaagccacc gcaggcccct gttctgctca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttgttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003401             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:14572:18999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003401
VERSION     KCWK01003401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14572:18999"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..443
                     /note="immunoglobulin light chain variable region"
     V_region        119..443
     V_segment       119..406
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69139.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       407..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          143 c          141 g          101 t
ORIGIN      
        1 acatgggcaa cgcagagtac atgggggggc ctcaggaggc agcattgacg gtgcctcagc
       61 catggcctgg acttttctcc tcctcggcct ccttgcttac tgcacaggct ctgcggcctc
      121 ctatgatctg actcagccag cctcggtgtc agtgtccccg ggacagacgg ccaggatcac
      181 ctgtggggga gacaatattg gaagtaaaaa tgtgcactgg taccagcagg agccaccgca
      241 ggcccctgtg ttggtcatct tttatgataa caaacggccc tcagggatcc ctgagcgatt
      301 ctctggctcc aaatcaggga acatcgccac cctgaccatc agcgaggccg aggccgggga
      361 tgaggctgac tattactgtc agctgtggga cagtagtgtt gatcatggct tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01003402             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:15332:12931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003402
VERSION     KCWK01003402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15332:12931"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69140.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          147 c          130 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcaacattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003403             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:6382:15226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003403
VERSION     KCWK01003403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6382:15226"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69141.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           81 a          158 c          128 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcagcact cagggacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctcc ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tattgttgct catataggag tggaaacact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003404             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:8519:20544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003404
VERSION     KCWK01003404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8519:20544"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69142.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       414..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          156 c          123 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccggaca gagggtcacc atctcctgca
      181 ttagcagcag ctccaacatc ggggcggctt attatgtatc ctggtaccaa cagttaccag
      241 gaacagcccc caaactcctc atctttgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtccctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattac tgtttagcat gggataccag cctgaattgg atcttcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003405             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:8074:6973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003405
VERSION     KCWK01003405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8074:6973"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69143.1"
                     /translation="VYYCGAWDSSLSGYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          156 c          124 g          110 t
ORIGIN      
        1 acatggggtc tgcctcagct gtgagcacag aaggcaggac ttgggacaat cttcatcatg
       61 acctggtccc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctacg gccccagggc agaaggtcac catctcctgc
      181 tctggaagta gctccaacat cgggagaaat tctgtatcct ggtaccagca ggtcccagga
      241 acggccccca aagtcctcat ctatgacaat aataagcgcc cctcgggggt ttctgaccga
      301 ttctctggct ccaagtctgg tacctcagcc tccctggcca tcactggact ccaggctgga
      361 gatgaggctg tttattactg cggagcatgg gatagcagtc tgagtggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003406             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:16516:9136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003406
VERSION     KCWK01003406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16516:9136"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..396
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69144.1"
                     /translation="DYYCQSFDSSTVLF"
     J_segment       402..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           81 a          157 c          129 g          107 t
ORIGIN      
        1 acatgggggg gctgtggctc aggaagcaga gcctggagca tctccaccat ggcctgggct
       61 ccgctcctcc tcaccctcct cgctcactgc acagggtctt gggctgaggt tgtgttcact
      121 cagccccaat ctgtgtcggg gtctccgggg cagacggtca ccatctcctg cacccgcagc
      181 agtggcagca ttggcaacag ctatgtgtac tggttccagc agcggccggg cagcgtcccc
      241 actattgtga tttacaaaga tgaccaaaga ccctctgggg tccctgatcg gttctctggc
      301 tccatcgaca gctcctccaa ctctgcctcc ctcaccatct ctggactgaa gtctggggac
      361 gaggctgact attactgtca gtcttttgac agcagcactg tcttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003407             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:14558:19464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003407
VERSION     KCWK01003407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14558:19464"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69145.1"
                     /translation="DYYCQSTDTSGNYIF"
     J_segment       386..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT          105 a          131 c          122 g          102 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gaggaatact
      181 ggcaaaaaaa tatgctcagt ggttgcagca gaagccaggc caggcccctg tgttggtaat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagtt ccagttcagg
      301 gacaacagtt gccttgacca tcagtggggc ccaggcagaa gatgaggctg attattactg
      361 tcaatcaaca gacaccagtg gtaattacat cttcggtgct gggacccggc tcaacgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003408             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:10553:6218
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003408
VERSION     KCWK01003408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10553:6218"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69146.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          138 c          134 g          103 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccagg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003409             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:20774:10209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003409
VERSION     KCWK01003409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20774:10209"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69147.1"
                     /translation="DYYCQMYDNSDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           94 a          160 c          120 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcaga tgtatgacaa tagtgatgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003410             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:13000:7852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003410
VERSION     KCWK01003410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13000:7852"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69148.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       397..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           85 a          150 c          136 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcgg cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcccctgtgg gggagacaac
      181 attggaacta aatatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
      241 atctatgctg ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gatatgaggc tgactatttc
      361 tgtcaggtgt gggacgatag tagtgatcat ccggttttcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003411             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:11490:6772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003411
VERSION     KCWK01003411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11490:6772"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..234
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <197..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69149.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       239..269
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           67 a           91 c           77 g           72 t
ORIGIN      
        1 acatggggga accagcagtg atattgggta ttatcatgct gtgtcttggt accaacatca
       61 tccaggcaaa gcccccaaac tcatgattta tgaggtcaat aaacggcccg caggggtctc
      121 tgatcgcttc tctggctcca agtctggcaa cacggcctcc ctgaccatct ctgggctcca
      181 gactgaggat gaggctgatt attactgcag ctcatatgca ggcagcaaca ctttattctt
      241 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01003412             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:13049:14529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003412
VERSION     KCWK01003412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13049:14529"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69150.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          154 c          127 g          112 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaacatt ggaggttatt atgtgcagtg gtaccagcag cttccaggaa
      241 cggcccccaa actcctcatc tatgaaaatg ataaacgacc ctcaggggtt tctgatcgat
      301 tctctggctc ccagtctgat tcctcagcct ccctgaccat cactggactc cagtctgagg
      361 atgaggctga ttattactgc cagtcctatg acagcagctt gagtgttgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003413             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:21001:3847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003413
VERSION     KCWK01003413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21001:3847"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69151.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          160 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatcctcg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaaataaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003414             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:11392:19176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003414
VERSION     KCWK01003414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:11392:19176"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..450
                     /note="immunoglobulin light chain variable region"
     V_region        105..450
     V_segment       105..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69152.1"
                     /translation="DYFCQGFDSSVVFF"
     J_segment       413..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           88 a          166 c          123 g          111 t
ORIGIN      
        1 acatggggaa ccctgggtct gtggcctcag aggtagccgt gtccaccatg gccctgactc
       61 ctctcctcct cctgctcctc tctcactgca caggttccct ctcccagcct gtgctgactc
      121 agccaccctc cctgtctgca tccccgggag catcggccag actcccctgc accctgagca
      181 gtgacctcag tgttggtagt aaaaacatgt actggtacca gcagaagcca gggagcgctc
      241 ccaggttatt cctgtactac tactccgact cagacaacca gctgggacct ggggtcccca
      301 atcgagtctc tggctccaag gagacctcaa gtaacacagc gtttttgctc atctctgggc
      361 tccagcctga ggacgaggcc gattatttct gccaggggtt tgacagtagt gttgtgttct
      421 tcggaggagg gacccgactg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01003415             283 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:22761:5132
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003415
VERSION     KCWK01003415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 283)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22761:5132"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..242
                     /note="immunoglobulin light chain variable region"
     V_region        13..242
     V_segment       13..208
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <170..>217
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69153.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       211..242
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        243..>283
                     /gene="IGLC"
BASE COUNT           58 a           86 c           82 g           57 t
ORIGIN      
        1 acatggggaa gttgttaact ggtaccagca gaagccaccg caggcccctg tcctggtcat
       61 ctatgctaat aacgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      121 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      181 tcaggtgtgg ggcgttacta gtgatcatcc cttattcgga ggagggaccc ggctgaccgt
      241 ccaaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003416             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:7734:21046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003416
VERSION     KCWK01003416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7734:21046"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69154.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           89 a          143 c          125 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacatg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003417             372 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:18134:11472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003417
VERSION     KCWK01003417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 372)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18134:11472"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..332
                     /note="immunoglobulin light chain variable region"
     V_region        117..332
     V_segment       117..295
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>306
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69155.1"
                     /translation="DYYCSIGHSSGLYIF"
     J_segment       297..332
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        333..>372
                     /gene="IGLC"
BASE COUNT           65 a          123 c           93 g           91 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 ccccggtttc ttctgaggta caaatcagac tcagataagg gccagggctc tggagtcccc
      181 agccgcttct ctggatccag taatgcttca gcgaacacag ggattttacg catttctggg
      241 ctccagtctg aggatgaggc tgactattac tgttccattg gacacagcag cggtctttac
      301 atcttcggtg ctgggacccg gctcaccgtc ctgggtcagc ccaaggcttc ccccacggtc
      361 actctgttcc cg
//
LOCUS       KCWK01003418             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:12488:3716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003418
VERSION     KCWK01003418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12488:3716"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69156.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          139 c          133 g          104 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagt ctctgtggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctt tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003419             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12278:10190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003419
VERSION     KCWK01003419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12278:10190"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69157.1"
                     /translation="DYYCQVYDSNAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          165 c          118 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg cagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctcta ctactactcc gactcagaca accaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgccagg tgtatgacag taatgctgtt ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003420             402 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:2286:11953
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003420
VERSION     KCWK01003420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 402)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:2286:11953"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    40..364
                     /note="immunoglobulin light chain variable region"
     V_region        40..364
     V_segment       40..315
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <289..>336
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69158.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       327..364
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        365..>402
                     /gene="IGLC"
BASE COUNT           82 a          124 c          113 g           83 t
ORIGIN      
        1 acatggggcc tcctcgctca ctgcacaggc tctgcgacct cctttgagct gactcagcca
       61 ccctcggtgt cagtggcctc aggacagacg gccaggatca cctgtggggg agacaacatt
      121 ggaattaaat ttgtccactg gtaccagcag aagccagcgc aggcccctgt gaaggtcatc
      181 tatgctgatg acaaacggcc ctcagggatc cctgagagat tctctggctc caattcaggg
      241 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattcctgt
      301 caggtgtggg acagtgagac tgatcattac atcttcggtg ttgggacccg gctcaccgtc
      361 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01003421             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:23881:21997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003421
VERSION     KCWK01003421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23881:21997"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69159.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       398..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          144 c          142 g           92 t
ORIGIN      
        1 acatggggag cctgggcctc aggaggcagc attgacggtg cctcagccat ggcctggact
       61 tttctcctcc tcggcctcct tgcttactgc acaggctctg cggcctccta tgatctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg cgggggagac
      181 aagattggaa gtgaagttgt gaactggtac cagaagaagc cagcgcaggc ccctgcactg
      241 gtcatctatg ctgatagcga acggccctca gggatccctg agcgattctc tggctccaaa
      301 tcagggaaca cggccaccct gaccatcagg ggggtcgagg ccgggggtga ggctgactat
      361 tactgtcagg tgtgggacat gcgtagtgat caaccgctat tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003422             323 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:6741:19106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003422
VERSION     KCWK01003422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 323)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:6741:19106"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..285
                     /note="immunoglobulin light chain variable region"
     V_region        8..285
     V_segment       8..253
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69160.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       254..285
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>323
                     /gene="IGLC"
BASE COUNT           72 a          101 c           90 g           60 t
ORIGIN      
        1 acatgggggg gcagacagtc aggattacct gccaaggaga cagcctcaga agctcttatg
       61 caaactggta ccaacagagg ccaggccagg cccctgtgct ggtcgtctat ggtaacaact
      121 accggccctc agggatccca gagcgattct ctggctccta ctcccgaaac acagcttcct
      181 tgaccatcac tggggctcag gtggaagatg aggctgacta ttactgtgac tcctgggaca
      241 gcagcggaac ccaattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg
      301 ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003423             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:13965:11655
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003423
VERSION     KCWK01003423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13965:11655"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69161.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          124 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagcgggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003424             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:4662:9606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003424
VERSION     KCWK01003424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4662:9606"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69162.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       396..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           93 a          150 c          116 g          110 t
ORIGIN      
        1 atggggtctg gagccaggga tcccttccaa tatcagcacc atggcctgga ctctgctcct
       61 cctccagttc ctcctcactt gctgcccagg gtccaattct caggctgtag tgactcagga
      121 gccctcaatg actgtgtccc caggagggac agtcactctc acctgtgctt ccagcactgg
      181 agcagtcacc agtggtcact ctccacactg gttccagcag aaacctggac aagcccccaa
      241 gacactgatt tataatacaa actacagaca ctcctggact cctgcccggt tctcaggctc
      301 cctccttggg ggtaaagctg ccctgacact gtcaggtgcg cagcctgagg atgaggctga
      361 gtattattgt ttactgtact atagtggtgc tcagctgtta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003425             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:8784:8308
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003425
VERSION     KCWK01003425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8784:8308"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69163.1"
                     /translation="DYYCCSYRSGPTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          158 c          128 g          107 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 caacagtgac attggaggtt atagtggcgt ctcctggtac cagcagcact cagggacagc
      241 ccccaaactc ctgatttatg atgtgaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgctgct catataggag tggacccact tgggttttcg gcggagggac
      421 ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003426             408 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:15771:8140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003426
VERSION     KCWK01003426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 408)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15771:8140"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    22..370
                     /note="immunoglobulin light chain variable region"
     V_region        22..370
     V_segment       22..331
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <298..>342
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69164.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       333..370
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        371..>408
                     /gene="IGLC"
BASE COUNT           83 a          126 c          101 g           98 t
ORIGIN      
        1 acatgggcag gttccctctc gcagcctgtg ctgactcagc caacctccct ctcagcttct
       61 cctggagcat cagccagact cacctgcacc ttgagcagtg gcatcagtgt tggtacttac
      121 aggatattct ggtaccagca gaggccaggg agtcctcccc ggtatcttct gaaccaccac
      181 acagactcag ataaacatca gggctctgga gtccccagcc gcttctctgg atccaaagat
      241 gcttcggcca atgcagggat tttgctcatc tctgggctcc agtctgagga tgaggctgac
      301 tattactgta tgatttggca caacaatgct tatgtgttat tcggaggagg gacccggctg
      361 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003427             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:9599:12500
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003427
VERSION     KCWK01003427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9599:12500"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69165.1"
                     /translation="DYHCQVYDGSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          160 c          123 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agtagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctacttctcc gactcagaca agcagttggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt actcatctct gggctccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtatgacgg tagtgctgtt ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003428             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:11947:16487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003428
VERSION     KCWK01003428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11947:16487"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69166.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          157 c          121 g          100 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgtctctg cctccctggg agcctcggtc aaactcacct gtactttgaa cagtgggcac
      181 agcagctaca ccatcgcatg gcatcagcag cagcaaggga aggccccccg gtacttgatg
      241 tggcttaaaa gtgaaggcag ccatagcaag ggggacggga tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatactgac attgtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003429             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:2090:11843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003429
VERSION     KCWK01003429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:2090:11843"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69167.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          162 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagag gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003430             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:18516:6630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003430
VERSION     KCWK01003430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18516:6630"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69168.1"
                     /translation="DYYCQSADSSGNHPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          106 a          133 c          123 g          101 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tcttcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatgctcagt ggttccagca gaagccaggc caggcccctg tgttggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgaacga ttctctagtt ccagtacagg
      301 gacaacactt accttgacca tcagtggggc ccaggtggaa gatgaggctg actattactg
      361 tcaatcagca gacagcagtg gtaatcatcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003431             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:20188:10098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003431
VERSION     KCWK01003431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20188:10098"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..233
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <197..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69169.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       237..269
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           69 a           86 c           91 g           61 t
ORIGIN      
        1 acatgggacc tgtgggggag acaacattgg aattaaaact gtacactggt accagcagaa
       61 gccaccgcag ggccctgtat tggtcatctt tgctgatagt aagcggccca cagggatccc
      121 tgagcgattc tctggctcca actcagggaa caccgccacc ctgaccatca gcagggtcga
      181 ggccggggat gaggctgact attactgtca ggtgtgggac agtagtagta aatggatatt
      241 cggcgggggg acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01003432             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:10084:15728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003432
VERSION     KCWK01003432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10084:15728"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..428
                     /note="immunoglobulin light chain variable region"
     V_region        103..428
     V_segment       103..393
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69170.1"
                     /translation="DYYCQSADGNYRVF"
     J_segment       394..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>467
                     /gene="IGLC"
BASE COUNT           86 a          162 c          120 g           99 t
ORIGIN      
        1 acatggggga ctcagaaagc agagcctggg gcgtctccac catggcctgg gctccactcc
       61 tcctcaccct cctcgctcac tgcacagggt cttgggctga acttgtgttc actcagcccc
      121 attctgtgtc ggggtctccg gggcagacgg tcaccatctc ctgcacccgc agcattggca
      181 acattgacag tgaatatgtg cagtggtacc agcagcgccc gggcagtgcc cccaccacac
      241 tgatttacaa agatagtcaa agaccctctg gggtccctga ccggttctct ggctccatcg
      301 acagctcctc caactctgcc tccctcgcca tctctgggct acagtctgag gacgaggctg
      361 actactactg tcagtctgct gatggcaact acagggtctt cggcggaggg acccggctaa
      421 ccgtcctaag tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003433             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:12007:17933
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003433
VERSION     KCWK01003433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12007:17933"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69171.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          161 c          112 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcaactcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 gttacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaaaatgc ttcaacgaac acaggcattt tacacatctc tgggctccag tctgaggatg
      361 aggctgacta tttctgtgcc attggacaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003434             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:20476:10476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003434
VERSION     KCWK01003434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20476:10476"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69172.1"
                     /translation="VYYCQVWDSSSEWLF"
     J_segment       394..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           90 a          146 c          134 g           92 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca gggtctgcga cctcctatga gctgactcag
      121 ccaccctcag tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaaggcag cacaggcccc tatgctggtc
      241 atctttgctg atagcaaacg gccctcaggg atccctgacc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgtctattac
      361 tgtcaggtgt gggacagtag tagtgagtgg cttttcggcg gagggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003435             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:15319:20237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003435
VERSION     KCWK01003435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15319:20237"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..429
                     /note="immunoglobulin light chain variable region"
     V_region        84..429
     V_segment       84..392
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69173.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       393..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          158 c          108 g          110 t
ORIGIN      
        1 acatggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc ctgctcctct
       61 ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc ctctcagcat
      121 ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcaatgtt ggtagttaca
      181 gcatattctg gtaccagcag aagccaggga gtcctccccg gtaccttctt tactactact
      241 cagactcaag taaccaccag gactctggag tccccagccg cttctctgga tcgaaagatg
      301 cttcagccaa tgcagggctt ttactgatct ctgggctcca gtctgaagat gaggctgact
      361 attactgtgc cacatggcac agcagcgctt cttacatctt cggtggtggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01003436             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:22704:14160
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003436
VERSION     KCWK01003436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22704:14160"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69174.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          162 c          113 g          110 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc accaatgttg
      181 gtagttacag gatattctgg taccagcaga agccagggag tcctccccgg taccttctgt
      241 actactactc agactcaact aagcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttgcatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003437             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:20821:16373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003437
VERSION     KCWK01003437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20821:16373"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..268
                     /note="immunoglobulin light chain variable region"
     V_region        7..268
     V_segment       7..229
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <193..>240
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69175.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       231..268
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        269..>306
                     /gene="IGLC"
BASE COUNT           65 a           90 c           76 g           75 t
ORIGIN      
        1 acatggggga gcagctccaa cattggagat tattatgtgc agtggtacca gcagcttcca
       61 ggaacggccc ccaaactcct catctatgaa aataataagc gaccctcagg ggtttctgat
      121 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      181 gacgatgagg ctgattatta ctgtcagtcc tatgatagca gcctgagtgt tgtgttattc
      241 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      301 ttcccg
//
LOCUS       KCWK01003438             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:4283:17729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003438
VERSION     KCWK01003438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:4283:17729"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69176.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          156 c          118 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgttggcta ccacatacac tggtaccagc agctgccagg gagtcgtccc cggtatcttc
      241 tgagatacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcaacg aacacaggga ttttacgcat ctctgggctc cagtctgacg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtgatg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003439             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:6650:18366
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003439
VERSION     KCWK01003439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6650:18366"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..260
                     /note="immunoglobulin light chain variable region"
     V_region        8..260
     V_segment       8..223
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>232
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69177.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       225..260
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>298
                     /gene="IGLC"
BASE COUNT           63 a           90 c           77 g           68 t
ORIGIN      
        1 acatggggga gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca
       61 agcccccaag acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt
      121 ctcaggctcc ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga
      181 tgaggctgag tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg
      241 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003440             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:6143:21465
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003440
VERSION     KCWK01003440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6143:21465"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69178.1"
                     /translation="DYYCQVWDISSDHVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          140 c          140 g           99 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctccgcgg cctcctttga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aacttgtgaa ctggtaccaa cagaggccac cgcaggcccc tgtgctggtc
      241 atgtatgctg atgacgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggagtacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacattag tagtgatcat gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003441             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:27130:12199
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003441
VERSION     KCWK01003441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:27130:12199"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    144..374
                     /note="immunoglobulin light chain variable region"
     V_region        144..374
     V_segment       144..337
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>346
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69179.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       341..374
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        375..>412
                     /gene="IGLC"
BASE COUNT           71 a          141 c          105 g           95 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatca gccagggagc gctcccaggt tattcctgta
      181 ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag tctctggctc
      241 caaggagacc tcaaataaca cagcgttttt gctcatctct gggctccagc ctgaggacga
      301 ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag gagggacccg
      361 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003442             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:21450:16082
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003442
VERSION     KCWK01003442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21450:16082"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69180.1"
                     /translation="VYYCAIGHSSGLYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           88 a          157 c          120 g          114 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca ttagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacgtacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg ggtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgaggctgt ctattactgt gccattgggc acagcagcgg tctttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003443             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:21433:5265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003443
VERSION     KCWK01003443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21433:5265"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69181.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          158 c          122 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acacctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003444             299 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:14998:11576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003444
VERSION     KCWK01003444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 299)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14998:11576"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..261
                     /note="immunoglobulin light chain variable region"
     V_region        6..261
     V_segment       6..225
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>233
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69182.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       229..261
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        262..>299
                     /gene="IGLC"
BASE COUNT           67 a           85 c           88 g           59 t
ORIGIN      
        1 acatgggggg agacaacatt ggaactaaaa ctgtgcactg gtaccaacag aagccaccgc
       61 agggccctgt attggtcatc tttgctgata gtagacggcc ctcagggatc cctgagcgat
      121 tctctggctc caactcaggg aacaccgcca ccctgaccat cagcagggtc gaggccgggg
      181 atgaggctga ctattactgt caggtgtggg acagtagtag taaatggata ttcggcgggg
      241 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003445             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:24308:14342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003445
VERSION     KCWK01003445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:24308:14342"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69183.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           81 a          163 c          122 g          102 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtggccac
      181 tacagctaca ccatcgcatg gcatcagcag cagcaaggga aggcccctcg gttcttgatg
      241 tggcttaaga gtgatggcag ccacaccaag ggggacgggg tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatattggc atttgggttt tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003446             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11907:11737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003446
VERSION     KCWK01003446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11907:11737"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69184.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       392..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          140 c          136 g          102 t
ORIGIN      
        1 acatggggct gactttggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactttacag gctctgtggc ctcctatgag ttgcctcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa tagtgtgcat tggtaccagc agaagccacc gcgggcccct gtattggtca
      241 tctctgttga tagcgaacgg ccctcaggga tccctgagcg attctctggt tccagatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggataatatt tataaatacg cggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003447             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:15241:15884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003447
VERSION     KCWK01003447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15241:15884"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69185.1"
                     /translation="DYYCCSRSSSSTYVF"
     J_segment       400..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           82 a          162 c          118 g          111 t
ORIGIN      
        1 acatgggggg gggtctcaga aggcagcgct ctcaggacgt ctccaccatg gcctggactc
       61 tgctcctcgt caccctcctc actcaaggca caggatcctg ggctcagtct gccccgactc
      121 agcctccctc tgtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacgt tggtggttat aactctgtct cctggtacca acaacaccca ggcaaagccc
      241 ccaaagtcat gatttttggt gtcaataatc ggccctctgg ggtctctgac cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagcct gaggacgagg
      361 ctgactatta ctgttgttca cgttcaagca gtagcactta cgtcttcggt cctgggaccc
      421 ggctcaccgt cctgggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003448             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:14218:11614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003448
VERSION     KCWK01003448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14218:11614"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69186.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          158 c          120 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc aacgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca actccaacat cggaacttat aatgtgtcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003449             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:15458:16105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003449
VERSION     KCWK01003449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15458:16105"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69187.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          152 c          123 g          106 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtctccatc tcctgttctg gaagcagctc
      181 caacatcgga agtcatagtg tctcctggta ccagcaagtc ccaggaacag ctcccaaact
      241 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctctca
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcatgggatg atagcctgag gggttacatc ttcggtgctg ggacccggct
      421 cgccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003450             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18413:7187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003450
VERSION     KCWK01003450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18413:7187"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69188.1"
                     /translation="DYYCNSYAGSNTLVF"
     J_segment       404..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          156 c          121 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtagttata accgtgtctc ctggtaccaa catcacccag acaaagcccc
      241 caaagtcatg atttatgagg gcagtcagcg gccctcaggg gtctctgatc gcttctctgc
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcaactcat atgcaggcag caatactttg gttttcggcg gagggacccg
      421 gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003451             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:12352:14636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003451
VERSION     KCWK01003451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12352:14636"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69189.1"
                     /translation="AYYCQVWDSDTDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          154 c          129 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 cccccctcgg tgtcagcggc ctcaggccag acggccagga tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaagccag cgcaggcccc tatgcaggtc
      241 atctatgctg atgccaaacg gccctcaggg atccctgaga gattctctgg ctccaactcc
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gagatgaggc tgcctattac
      361 tgtcaggtgt gggacagtga tactgatcat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003452             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:5379:15792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003452
VERSION     KCWK01003452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:5379:15792"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..401
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69190.1"
                     /translation="DYYCASYEGSNTFLF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          158 c          121 g          106 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc agtggaacca
      181 gcactaagat tgggtatcac aatgctgtgt cctggtacca agagcatcca ggcaaagccc
      241 ccaaactcat gatttttgac gtcaataagc ggcccacagg gatctctgat cggttctctg
      301 gctccaagtc tggcgacacg gcctccctga ccatctctgg gctccaggct gatgatgagg
      361 ctgattatta ctgcgcctca tatgaaggca gcaacacttt cctcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003453             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:11740:5696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003453
VERSION     KCWK01003453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11740:5696"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..404
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69191.1"
                     /translation="DYYCASYEGSNTFLF"
     J_segment       408..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           88 a          159 c          123 g          106 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccccga
      121 ctcagcctcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcagtggaa
      181 ccagcactaa gattgggtat cacaatgctg tgtcctggta ccaagagcat ccaggcaaag
      241 cccccaaact catgattttt gacgtcaata agcggcccac agggatctct gatcggttct
      301 ctggctccaa gtctggcgac acggcctccc tgaccatctc tgggctccag gctgatgatg
      361 aggctgatta ttactgcgcc tcatatgaag gcagcaacac tttcctcttc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003454             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:11112:17444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003454
VERSION     KCWK01003454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11112:17444"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69192.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          161 c          111 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacta ctcagactca agtaaacacc aggactctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttagtgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003455             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:8922:3578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003455
VERSION     KCWK01003455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8922:3578"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69193.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       408..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          157 c          117 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatatac tggtaccacc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tgactatatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003456             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:7700:17203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003456
VERSION     KCWK01003456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7700:17203"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69194.1"
                     /translation="DYYCSSYAGCDTFVSF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          161 c          124 g          105 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcgtg atttatgagg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggc ctccagcctg aggacgaggc
      361 tgattattac tgcagctcat atgcaggctg cgacactttc gtgtcattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003457             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:9182:9735
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003457
VERSION     KCWK01003457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9182:9735"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..451
                     /note="immunoglobulin light chain variable region"
     V_region        118..451
     V_segment       118..414
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69195.1"
                     /translation="DYYCQSYDSNLSAMLF"
     J_segment       416..451
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT           90 a          155 c          129 g          115 t
ORIGIN      
        1 acatgggggg ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gtagttccaa cttcggggcg ggttattatg tgcactggta ccagcaactt
      241 ccaggaacgg cccccaaact cctcatctat gaaaacaata tgcgaccctc aggggtttct
      301 gatcgattct ctggctccaa gtctggtacc tcagcctccc tgaccatcac tggactccag
      361 tctgaggatg aggctgatta ttactgccag tcctatgaca gtaatttgag tgctatgtta
      421 ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCWK01003458             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:23061:7499
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003458
VERSION     KCWK01003458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:23061:7499"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69196.1"
                     /translation="DYHCQVWDLNSHHLLF"
     J_segment       389..424
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           87 a          141 c          135 g           99 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcgattt cagtgtcccc aggacagacg gccagggtca cctgtggggg agacaacatt
      181 gggagtgaag ttgtgaactg gtaccagcag aagccaccgc aggcccctgt gttggtcatc
      241 tatgctgata gcgagcggcc ctcagggatc cctgaacgat tctctggctc caaatcaggg
      301 aacacggcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctatcactgt
      361 caggtgtggg accttaatag tcatcatttg ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003459             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:13902:13774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003459
VERSION     KCWK01003459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13902:13774"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69197.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           86 a          158 c          126 g          111 t
ORIGIN      
        1 acatgggggg cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggcac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcttggga tgatagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcgccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01003460             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16818:18766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003460
VERSION     KCWK01003460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16818:18766"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    42..336
                     /note="immunoglobulin light chain variable region"
     V_region        42..336
     V_segment       42..292
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69198.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       306..336
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           77 a          111 c           98 g           88 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctcctgga cagtcggtca
       61 ccatctcctg cactggaacc agcagtgata ttgggtatta tcatgctgtg tcttggtacc
      121 agcatcatcc aggcaaagcc cccaaactca tgatttatga ggtcaataaa cggcccgcag
      181 gggtctctga tcgcttctct ggctccaagt ctggcaacac ggcctccctg accatctctg
      241 ggctccagac tgaggatgag gctgattatt actgtagctc atatgcaggc agcaacagtt
      301 tattcttcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      361 tcactctctt cccg
//
LOCUS       KCWK01003461             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20892:16162
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003461
VERSION     KCWK01003461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20892:16162"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..408
                     /note="immunoglobulin light chain variable region"
     V_region        78..408
     V_segment       78..364
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69199.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       378..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           84 a          145 c          111 g          106 t
ORIGIN      
        1 acatggggga cttctccacc atggtctggg ctctgctcct cctcaccctc ctcactcagg
       61 gcacaggatc ctgggctcag gctgccccga ctcagactcc ctctgtgtcc gggtctcctg
      121 gacagtcggt caccatctcc tgcactggaa ccagcagtga tattgggtat tatcatgctg
      181 tgtcttggta ccagcatcat ccaggcaaag cccccaaact catgatttat gaggtcaata
      241 aacggcccgc aggggtctct gatcgcttct ctggctccaa gtctggcaac acggcctccc
      301 tgaccatctc tgggctccag actgaggatg aggctgatta ttactgtagc tcatatgcag
      361 gcagcaacag tttattcttc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003462             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:21536:18712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003462
VERSION     KCWK01003462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21536:18712"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69200.1"
                     /translation="DYYCAAWDDSLTGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          155 c          114 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccgg gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaacta atagtgtatc ctggtaccaa caactcccag aaacggctcc caaactcctc
      241 atgtattata gtcatcggcg aacctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacttcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgaccggt tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003463             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:11193:10543
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003463
VERSION     KCWK01003463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:11193:10543"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..401
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69201.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       403..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           87 a          152 c          122 g          113 t
ORIGIN      
        1 acagggggct gggatctcag gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggttcaggc tgccccgact
      121 cagcctccct ctgtgtccgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgata ttgggtatta taacgctgtg tcttggtacc aacagcatcc aggcaaagcc
      241 cccaaactca taatttttga cgtcattaag cggccctcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcgacac ggcctccctg accatctctg ggctccgggc tgaggatgag
      361 gctgattatt actgcagctc atatgcaggc agaaataatt ttttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003464             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10710:16916
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003464
VERSION     KCWK01003464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10710:16916"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69202.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          156 c          125 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaggca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgataggc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003465             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:13323:20761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003465
VERSION     KCWK01003465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13323:20761"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69203.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          147 c          130 g           97 t
ORIGIN      
        1 acatgggggt gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003466             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:11699:4042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003466
VERSION     KCWK01003466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11699:4042"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69204.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtacact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttgttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003467             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:19685:18309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003467
VERSION     KCWK01003467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19685:18309"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..416
                     /note="immunoglobulin light chain variable region"
     V_region        123..416
     V_segment       123..381
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69205.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       386..416
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           90 a          147 c          114 g          103 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactcctgga cagtcggtca ccatctcctg cactggaacc agcagtgata ttgggtatta
      181 tcatgctgtg tcttggtacc aacatcatcc aggcaaagcc cccaaactca tgatttatga
      241 ggtcaataaa cggcccgcag gggtctctga tcgcttctct ggctccaagt ctggcaacac
      301 ggcctccctg accatctctg ggctccagac tgaggatgag gctgattatt actgcagctc
      361 atatgcaggc agcaacactt tattcttcgg aggagggacc cggctgaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003468             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:18651:7981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003468
VERSION     KCWK01003468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18651:7981"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69206.1"
                     /translation="DYYCAVWSSSAYIF"
     J_segment       403..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           83 a          157 c          118 g          118 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctgt cacagcctgt gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagtcagac tcacctgcac cttgcgcact ggcctcaatg
      181 ttggtggcta ctacatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgaattacta ctcagactca aatcagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgtttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccgtttggt ccagcagcgc ttacatcttc ggtggtggga
      421 ctcggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003469             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:10702:5227
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003469
VERSION     KCWK01003469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:10702:5227"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..444
                     /note="immunoglobulin light chain variable region"
     V_region        96..444
     V_segment       96..405
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69207.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       407..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           97 a          157 c          111 g          117 t
ORIGIN      
        1 acatggggcc cactgcaggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcgcagcc tgtgctgact cagccaacct
      121 ccctctcagc atctcctgga gcatcagcca gactcacctg caccttgaac agtggcatca
      181 gtgttgctaa ttacaggata ttctggtacc accagaagcc agggagtcct ccccggtatc
      241 ttctgaacta ccacacagac tcagatattc atcagggctc tggagtcccc agccgcttct
      301 ctggatccaa agatgcttcg gccaatgcag ggattttact catctctgga ctccagtctg
      361 aggatgaggc tgactattac tgtatgattt ggcacaacaa tgcttattgg gttttcggcg
      421 gagggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003470             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:22093:6795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003470
VERSION     KCWK01003470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:22093:6795"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69208.1"
                     /translation="DYYCQSYDSSLSGVLF"
     J_segment       416..450
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           91 a          155 c          129 g          113 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcagtgg gagcaactcc aacattggat actattatgt gcagtggtac cagcagcttc
      241 cagggacggc ccccaaactc ctcatctatg aaaataataa gcgaccctct ggggtttctg
      301 atcgattctc tggctcccag tctggtacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagtttgagt ggtgtcttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01003471             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:24131:11279
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003471
VERSION     KCWK01003471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24131:11279"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69209.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       409..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          156 c          128 g          106 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcctcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaatag tgtatcctgg taccagcagc tcccagaaac
      241 ggctcccaaa ctcctcatct tttataatga tcggcgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agcggtccgg tattcggcgg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01003472             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:24099:10576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003472
VERSION     KCWK01003472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:24099:10576"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69210.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          152 c          117 g          113 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcactgttg
      181 ctggctacca tatatattgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatatc tggactccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacaca gcagcggtga ttatatcttc ggtgctggga
      421 cccgtctcac cgtcctaggt cagcccaagg cttcccccac ggttactctg ttcccg
//
LOCUS       KCWK01003473             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:11124:14674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003473
VERSION     KCWK01003473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11124:14674"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..442
                     /note="immunoglobulin light chain variable region"
     V_region        113..442
     V_segment       113..404
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69211.1"
                     /translation="DYYCSAWDSSLTGGLF"
     J_segment       406..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>481
                     /gene="IGLC"
BASE COUNT           97 a          154 c          122 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt ggctagagaa gacaggactc aggacaatct ccagcatggc
       61 ctgcttccct ctcatcctca ccgtcctcac tcactgtgca ggatcctggg cccagtctgt
      121 gctgactcaa ccaccctcag cgtctggggc ccccgggcag agtgtcacca tctcctgttc
      181 tggaagcagt tccaacatcg gaagtcatta tgtatattgg taccagcagt tctcaggaaa
      241 ggcccccaaa ctcctcatct ataatgataa tgagcgaccc tcaggggtcc ctgatcgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agtccgagga
      361 tgaggctgat tattactgct cagcatggga tagcagcctg accggtggct tattcggagg
      421 agggacccgc ctgaccgtcc taagtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01003474             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:9738:4071
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003474
VERSION     KCWK01003474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:9738:4071"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69212.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          143 c          131 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctttga attgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tatattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003475             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:10819:16370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003475
VERSION     KCWK01003475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:10819:16370"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69213.1"
                     /translation="DYYCAAWDNSLTSPLL"
     J_segment       393..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          154 c          115 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaacta attatgtata ctggtaccag cagctcccag gaacggcccc caaagtcctc
      241 atctattata gtaatcagcg accctcaggg gtccctgacc gattctctgc ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcgt gggataacag cctaactagt ccgttactcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003476             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:10719:8229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003476
VERSION     KCWK01003476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:10719:8229"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69214.1"
                     /translation="DYYCQVWDTSIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          147 c          128 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtga gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tatactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003477             332 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:24894:6812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003477
VERSION     KCWK01003477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 332)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24894:6812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..294
                     /note="immunoglobulin light chain variable region"
     V_region        84..294
     V_segment       84..254
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>266
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69215.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       258..294
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>332
                     /gene="IGLC"
BASE COUNT           58 a          100 c           96 g           78 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg cccctgtggt ggtcatctat gctgattatg
      121 aacggccctc agggatccct gagcgattct ctggctccaa atcagggaac acggccaccc
      181 tgaccatcag cggagtcgag gccggggatg aggctgacta ttactgtcag gtttgggaca
      241 tttatattga tcatccggtg ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      301 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003478             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11615:18235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003478
VERSION     KCWK01003478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11615:18235"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..268
                     /note="immunoglobulin light chain variable region"
     V_region        7..268
     V_segment       7..231
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <193..>240
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69216.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       232..268
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        269..>306
                     /gene="IGLC"
BASE COUNT           66 a           91 c           74 g           75 t
ORIGIN      
        1 acatggggga gcagctccaa cattggagat tattttgtgc agtggtacca gcaccttcca
       61 ggaacggccc ccaaactcct catctatgaa aataataagc gaccctcagg gatttctgat
      121 cgattctctg gctcccagtc tggaacctca gcctccctga ccatcactgg actccagtct
      181 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtttgattgc tgtgttattc
      241 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      301 ttcccg
//
LOCUS       KCWK01003479             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:6982:7808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003479
VERSION     KCWK01003479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6982:7808"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69217.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          143 c          133 g          102 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtgctggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgacc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003480             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:27711:8061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003480
VERSION     KCWK01003480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:27711:8061"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69218.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           82 a          164 c          121 g          101 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtggccac
      181 tacagctaca ccatcgcatg gcatcagcag cagcaaggga aggcccctcg gttcttgatg
      241 tggcttaaga ctgatggcag ccacaccaag ggggacgggg tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatattggc atttgggtat tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003481             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:1976:12227
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003481
VERSION     KCWK01003481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:1976:12227"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69219.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       400..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           83 a          160 c          126 g           99 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tctttcactg cacagggtct ctctcccagc ctgtggtgac tcagtcgtcc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cggtgggcac
      181 agcgactaca ccatcgcatg gcatcagcag cagcaaggga aggcccctcg gtatttgatg
      241 tggcttaaaa gtgatggcag ccacagcaag ggggacggga tccctgatcg cttctccggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggagactggc attcaggtgt tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003482             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:23514:13379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003482
VERSION     KCWK01003482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23514:13379"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69220.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          150 c          122 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgta
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctctt gttctggaag catctccagc
      181 attggaagta gtgatgtatg ttggtaccag caactcccag gaacggcccc caaactcctc
      241 atcaattata gtgatcagcg actctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcct gggatagcag cctgagcagt ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003483             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:10455:20156
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003483
VERSION     KCWK01003483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10455:20156"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..422
                     /note="immunoglobulin light chain variable region"
     V_region        92..422
     V_segment       92..385
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69221.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       386..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           85 a          153 c          119 g          103 t
ORIGIN      
        1 acatggggag gcaggactca ggacaatctc cagcatggcc tggttccctc tcgtcctcac
       61 cctcctcact cactgtgcag ggtcctgggc ccagtctgtg ctgactcagc ctccctcagc
      121 gtctgaggcc gccaggaaga gtgtctccat ctcctgttcg ggaagcagct ccaacatcgg
      181 aagtcatagt gtctcctggt accagcaact cccaggaaca gctcccaaac tcctcatcta
      241 ttatagtgat caacgagcct caggtgtctc tgaccgattc tctggctccc agtctggcac
      301 gtcagcctcc ctggccatca gtgggctcca gaccgaggat gaggctgatt attactgcgc
      361 ggcatgggat gatagcctga gcggttacat cttcggtggt gggacccggc tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003484             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:14240:13101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003484
VERSION     KCWK01003484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14240:13101"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69222.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          158 c          113 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgtcccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003485             353 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:11466:14732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003485
VERSION     KCWK01003485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 353)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11466:14732"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..315
                     /note="immunoglobulin light chain variable region"
     V_region        8..315
     V_segment       8..271
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>287
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69223.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       278..315
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        316..>353
                     /gene="IGLC"
BASE COUNT           70 a          110 c           85 g           88 t
ORIGIN      
        1 acatgggctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
       61 gcagtgatat tgggtcttat aatgctgtgt cctggtacca acagcatcca ggcaaagccc
      121 cccaactcat aatttttgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      181 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      241 ctgattatta ctgctgctca tatgtaggca gcaacactta catcttcgat attgggaccc
      301 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003486             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:14487:6077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003486
VERSION     KCWK01003486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14487:6077"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69224.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       398..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           91 a          152 c          119 g          110 t
ORIGIN      
        1 acatggggga caggaggcag cactcaggac agtctccagc atggcctggt ctcctctcct
       61 cctcaccctt ctcattcact tcacagttcc agggtcctgg gcccagtctg tgctgacgca
      121 gccgccctca gtgtctgggg cgcccgggca gagggtcacc atctcctgca ctgggagcag
      181 ctccaacatt ggagattatt ttgtgcagtg gtaccagcac cttccaggaa cggcccccaa
      241 actcctcatc tatgaaaata ataagcgacc ctcagggatt tctgatcgat tctctggctc
      301 ccagtctgga acctcagcct ccctgaccat cactggactc cagtctgagg atgaggctga
      361 ttattactgc cagtcctatg acagcagttt gattgctgtg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003487             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:22968:11371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003487
VERSION     KCWK01003487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22968:11371"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..303
                     /note="immunoglobulin light chain variable region"
     V_region        8..303
     V_segment       8..266
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <228..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69225.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       267..303
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           71 a          107 c           85 g           78 t
ORIGIN      
        1 acatgggggc cgccaggaag agtgtcacca tctcctgttc tggaagcaac tccaacatcg
       61 gaagttataa tgtgtcctgg taccagcagc tcccaggaac agctcccaaa ctcctcatct
      121 attataatga tcaacgagcc tcaggtgtct ctgaccgatt ctctggctcc aagtctggca
      181 cgtcagcctc cctggccatc agtgggctcc agaccgagga tgaggctgat tattactgcg
      241 cggcatggga tgatagcctt agcggttaca tcttcgctgc tgggacccgg ctcaccgtcc
      301 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01003488             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:10245:15253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003488
VERSION     KCWK01003488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10245:15253"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69226.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       406..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           96 a          155 c          116 g          110 t
ORIGIN      
        1 acatggggtg tggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc aagcctatgc tgactcagcc ggcctccctc
      121 tcagcatctc ctggaacatc agccagtctc acatgcacct tcagcggtgg catcaatgtt
      181 gctggctacc acatatactg gtaccaccag aagccaggga gtcccccccg gtatcttctg
      241 aggtacaaat cagactcaga taagggccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcagcgaa cacagggatt ttacacatct ctggactcca gtctgaggat
      361 gaggctgact attactgtgc cattggacac agcagcggtg attatatctt cggtggtggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01003489             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20088:5227
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003489
VERSION     KCWK01003489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20088:5227"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..426
                     /note="immunoglobulin light chain variable region"
     V_region        123..426
     V_segment       123..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69227.1"
                     /translation="DYYCQVWDINSHHLLF"
     J_segment       391..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           92 a          134 c          135 g          103 t
ORIGIN      
        1 acatgggatc aacgcagagt acatggggct gggcctcagg aggcagcatt gacggtgcct
       61 cagccatggc ctggactttt ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg
      121 cctcctatga tctgactcag gcaccctcga tttcagtgtc tcctggacag acggccagga
      181 tcacctgtgg ggaagacaat attggaagtg aagttgtgaa ctggtaccag cagaagccac
      241 cgcaggcccc tgtgttggtc atctatgctg atagcgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacattaat agtcatcatc tgttattcgg aggagggacc cggctggccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003490             453 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:6208:9464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003490
VERSION     KCWK01003490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 453)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:6208:9464"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..415
                     /note="immunoglobulin light chain variable region"
     V_region        91..415
     V_segment       91..377
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69228.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       383..415
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>453
                     /gene="IGLC"
BASE COUNT           87 a          141 c          134 g           91 t
ORIGIN      
        1 acatggggag gcagcattga cggtgcctca gccatggcct ggacttttct cctcctcggc
       61 ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc accctcggtg
      121 tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat tggaagtgaa
      181 gttgtgaact ggtaccagca gaagccagcg cacgcccctg tgctggtcat ctatgctaat
      241 agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg gaacacggcc
      301 accctgacca tcagcggggt cgaggccggg ggtgaggctg actattactg tcaggtgtgg
      361 gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt cctaggtcag
      421 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003491             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:24712:4710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003491
VERSION     KCWK01003491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24712:4710"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69229.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           97 a          153 c          113 g          114 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcg cagcctgtgc tgactcagcc aacctccctc
      121 tcagcatctc ctggagcatc agccagactc acctgcacct tgaacagtgg catcagtgtt
      181 ggtaattaca ggatattctg gtaccaccag aagccaggga gtcctccccg gtatcttctg
      241 aactaccaca cagactcaga tattcaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcggccaa tgcagggatt ttactcatct ctggactcca gtctgaggat
      361 gaggctgact attactgtat gatttggcac aacaatgctt attgggtatt cggcggaggg
      421 acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003492             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:18828:13313
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003492
VERSION     KCWK01003492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18828:13313"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..435
                     /note="immunoglobulin light chain variable region"
     V_region        87..435
     V_segment       87..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69230.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           95 a          162 c          109 g          107 t
ORIGIN      
        1 acatgggggg gaaagaggct gtgtccacca tggcctggac tcctctcctc ctcctgctcc
       61 tctctcactg cacaggttcc ctctccaagc ctatgctgac tcagccggcc tccctctcag
      121 caactcctgg agcatcagcc agtctcacat gcaccttcag cggtggcatc aatgttgctg
      181 cctaccacat acactggtac cagcagaagc cagggagtcc cccccggtat cttctgactt
      241 acaaatcaga ctcagataag ggccagggct ctggagtccc cagccgcttc tctggatcca
      301 aaaatgcttc aacgaacaca ggcattttac acatctctgg gctccagtct gaggatgagg
      361 ctgactattt ctgtgccatt ggacacagca gcggtcctta catcttcggt gctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003493             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:24225:17579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003493
VERSION     KCWK01003493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24225:17579"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..433
                     /note="immunoglobulin light chain variable region"
     V_region        88..433
     V_segment       88..396
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69231.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           91 a          161 c          108 g          111 t
ORIGIN      
        1 catggggcag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gaacatcagc cagactcagc tgcaccttga gcagtggcaa tgttggtagt
      181 tacagcatat tctggtacca gcagaagcca gggagtcctc cccggtacct tctttactac
      241 tactcagact caagtaacca ccaggactct ggagtcccca gccgcttctc tggttcgaaa
      301 gatgcttcag ccaatgcagg gcttttactg atctctgggc tccagtctga agatgaggct
      361 gactattact gtgccacatg gcacagcagc gcttcttaca tcttcggtcc tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01003494             380 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:21305:17395
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003494
VERSION     KCWK01003494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 380)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:21305:17395"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..342
                     /note="immunoglobulin light chain variable region"
     V_region        12..342
     V_segment       12..306
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <270..>314
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69232.1"
                     /translation="YYYCSSYAGSHTYIF"
     J_segment       307..342
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        343..>380
                     /gene="IGLC"
BASE COUNT           67 a          130 c           92 g           91 t
ORIGIN      
        1 acatgggggc tcaggctgcc ctgactcagc ctccctctgt gtctgggtct cctggacagt
       61 cggtcaccat ctcctgcact ggaaccagca gtgacatcgg tggttataac tatgtctcct
      121 ggttccagca gcaccccggc aaagccccca aactcatgat ttatgatgtc actcagcggc
      181 cctcaggggt ctctgatcgc ttctctggct ccaaatctgg ctacacggcc tccctgacca
      241 tctctgggct ccaggctgcg gatgaggctt attattactg cagctcatat gcgggcagcc
      301 acacttacat cttcggtact gggacccggc tcaccgtcct aggtcagccc aaggcttccc
      361 ccacggtcac tctgttcccg
//
LOCUS       KCWK01003495             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:24250:15027
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003495
VERSION     KCWK01003495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24250:15027"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69233.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          139 c          139 g           99 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 gcaccctcga tttcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atgtatgctg atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacatgaa tagtcatcat ctgttattcg gaggggggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003496             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:18177:4096
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003496
VERSION     KCWK01003496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:18177:4096"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..439
                     /note="immunoglobulin light chain variable region"
     V_region        93..439
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69234.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       407..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>479
                     /gene="IGLC"
BASE COUNT           89 a          164 c          113 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaccaatg
      181 ttggtagtta cagcattttc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca actaagcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgattcagcc aatgcagggc ttttactgat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccatttggc acagcagcgc ttcttgcatc ttcggtcctg
      421 ggacccggct caccgtcctg ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003497             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:19991:14703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003497
VERSION     KCWK01003497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:19991:14703"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69235.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          143 c          131 g           93 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgaat tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa actgtgcact ggtaccaaca gaagccaccg cagggccctc tattggtcat
      241 ctttgctgat agtagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003498             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:23776:14000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003498
VERSION     KCWK01003498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:23776:14000"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69236.1"
                     /translation="DYHCQSADSSGNHPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          106 a          133 c          123 g          101 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatgctcagt ggttccagca gaagccaggc caggcccctg tgttggttat
      241 atataaagac agtgagaggc cctcagggat ccctgaacga ttctctagtt ccagttcagg
      301 gacaacagtt accttgacca tcagtggggc ccaggtagaa gatgaggctg actatcactg
      361 tcaatcagca gacagcagtg gtaatcatcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003499             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:5938:8142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003499
VERSION     KCWK01003499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:5938:8142"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    72..407
                     /note="immunoglobulin light chain variable region"
     V_region        72..407
     V_segment       72..370
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <335..>379
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69237.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       373..407
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>445
                     /gene="IGLC"
BASE COUNT           85 a          145 c          116 g           99 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctcagccac cctccctgtc tgcatccccg ggagcatcgg ccagactccc
      121 ctgcaccctg agcagtgacc tcagtgttgg tagtaaaaac atgtactggt accagcagaa
      181 gccagggagc gctcccaggt tattcctgta ctactactcc gactcagaca agcagctggg
      241 acctggggtc cccaatcgag tctctggctc caaggagacc tcaagtaaca cagcgttttt
      301 gctcatctct gggctccagc ctgaggacga ggccgattat tactgtcagg tgtatgacag
      361 tagtgctaat gtcttattcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc
      421 tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003500             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:10691:8874
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003500
VERSION     KCWK01003500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10691:8874"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..449
                     /note="immunoglobulin light chain variable region"
     V_region        116..449
     V_segment       116..412
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69238.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       413..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           87 a          164 c          132 g          104 t
ORIGIN      
        1 acatgggggc agtgtggctg cctcagcaga gccctgagga gtctgcacca tggcctggac
       61 cccaatcctc ctcctcctcc tcactctcct ccttcactgc acagggtctc tctcccagcc
      121 tgtgctgact cagtcgccct ctgcctctgc ctccctggga gcctcggtca agctcacctg
      181 cactctgagc agtggacaca ggagctacac catcgcgtgg catcagcagc agcaagggaa
      241 ggcccctcga tacttgatgt ggcttaaaag tgatggcagc cacagcaagg gggacgggat
      301 ccctgatcgc ttctcaggct ccagctccgg ggctgagcgc tacctcacca tctccaacct
      361 ccagtctgag gatgaggctg attattattg tcagacgtgg gatattggca tttgggtgtt
      421 cggcggaggg acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01003501             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:5489:10598
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003501
VERSION     KCWK01003501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5489:10598"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..439
                     /note="immunoglobulin light chain variable region"
     V_region        113..439
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69239.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>481
                     /gene="IGLC"
BASE COUNT           88 a          155 c          127 g          111 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc aggccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagtctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcgccgtcg taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01003502             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:21735:8421
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003502
VERSION     KCWK01003502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21735:8421"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69240.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          164 c          108 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcagtg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctggcctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcgatactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003503             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:28107:13917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003503
VERSION     KCWK01003503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:28107:13917"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69241.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          144 c          131 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg gtctggggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tattggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003504             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:23376:12890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003504
VERSION     KCWK01003504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:23376:12890"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..343
                     /note="immunoglobulin light chain variable region"
     V_region        13..343
     V_segment       13..299
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69242.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       313..343
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>381
                     /gene="IGLC"
BASE COUNT           73 a          122 c           97 g           89 t
ORIGIN      
        1 acatgggggg ctcaggctgc cccgactcag actccctctg tgtccgggtc tcctggacag
       61 tcggtcacca tctcctgcac tggaaccagc agtgatgttg ggtattatca tgctgtgtct
      121 tggtaccagc atcatccagg caaagccccc aaactcatga tttatgaggt caataaacgg
      181 cccgcagggg tctctgatcg cttctctggc tccaagtctg gcaacacggc ctccctgacc
      241 atctctgggc tccagactga ggatgaggct gattattact gcagctcata tgcaggcagc
      301 aacgctttat tcttcggacg agggacccgc ctgaccgtcc taggtcagcc caaggctgcc
      361 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003505             510 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:8086:9802
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003505
VERSION     KCWK01003505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 510)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8086:9802"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    142..472
                     /note="immunoglobulin light chain variable region"
     V_region        142..472
     V_segment       142..435
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <397..>444
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69243.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       436..472
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        473..>510
                     /gene="IGLC"
BASE COUNT          100 a          161 c          136 g          113 t
ORIGIN      
        1 acatggggga agagagggag agatttgggt gaagcgcagc ttcagctgtg ggtacagaag
       61 gcaggactca ggacaatctc cagcatggcc tggttccctc tcgtcctcac cctcctcact
      121 cactgtgcag ggtcctgggc ccagtctgtg ctgactcaac ctccctcagc gtctgaggcc
      181 accaggaaga gtgtctccat ctcctgttct ggaagcagct ccaacatcgg aagtcatagt
      241 gtctcctggt accagcagct cccaggaaca gctcccaaac tcctcatcta ttatagtgat
      301 caacgcgcct caggtgtctc tgaccgattc tctggctcca agtctggcac gtcagcctcc
      361 ctggccatca gtgggctcca gaccgacgat gaggctgatt attactgcgc agcgtgggat
      421 gatagcctga gcggttacat cttcggtgct gggacccggc tcaccgtcct aggtcagccc
      481 aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003506             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:14379:16036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003506
VERSION     KCWK01003506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14379:16036"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69244.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          137 c          135 g          104 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggttgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003507             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:26250:8145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003507
VERSION     KCWK01003507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:26250:8145"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69245.1"
                     /translation="DYYCQMWGMTSDHPVF"
     J_segment       392..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          138 c          142 g           98 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagt
      121 caccctcggt gtcagagtct ccaggacaga cggccaggat cacctgtggg ggagacaaga
      181 ttggaagtga agttgtgaat tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tctctggtga tagcgagcgg ccctcaggga tccctgagcg attctctggc tccaagtcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcagatgtg gggcatgact agtgatcatc cggtattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003508             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:10713:9991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003508
VERSION     KCWK01003508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:10713:9991"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69246.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          141 c          138 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggggaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003509             450 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:26674:10939
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003509
VERSION     KCWK01003509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:26674:10939"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..412
                     /note="immunoglobulin light chain variable region"
     V_region        88..412
     V_segment       88..375
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69247.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       376..412
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>450
                     /gene="IGLC"
BASE COUNT           91 a          145 c          112 g          102 t
ORIGIN      
        1 tcagaagcag aactctgggt cctctccacc atggcctgga cccctcccct gctcatcctc
       61 ctcactctct gcacaggttc cgtggtttcc tctgagctga ctcaggagcc tgcattgtct
      121 gtggccttgg gacaaacagt caggatgacc tgccaaggag acagcctcaa aacctattat
      181 gcaagctggt accagcagaa gccaggccag gtccctgtgc tggtcatcta tggtaacaac
      241 taccggccct cagggatccc aggccgattc tctgtctcct ggtcaggaaa cacaggttcc
      301 ttgaccatca ctgcggctca ggtggaagat gaggctgact attactgtaa gtcctgggac
      361 agcagtggta cccattacat cttcggtgct gggacccggc tcaccgtcct aggtcagccc
      421 aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003510             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:18342:18074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003510
VERSION     KCWK01003510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:18342:18074"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69248.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           93 a          159 c          124 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg acgcagccac
      121 cctccctgtc tgcatccccg ggagcaccgg ccagactccc ctgcaccctg agcagtgact
      181 tcagtgttgg tggtaaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tatttctgta ctacaaatcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tatatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003511             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:12409:6305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003511
VERSION     KCWK01003511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:12409:6305"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69249.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          160 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacgg ggccgattat tactgtcagg tgtatgacga tagtgctgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003512             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:18701:10732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003512
VERSION     KCWK01003512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18701:10732"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69250.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          148 c          131 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgcgcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003513             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:2853:13550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003513
VERSION     KCWK01003513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:2853:13550"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69251.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          156 c          126 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagagtcac catctcctgt
      181 tctggaagca gttccaacat cggaagtaat agtgtatcct ggtaccagca gctcccagga
      241 actgctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctggccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagcgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003514             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:20414:21036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003514
VERSION     KCWK01003514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20414:21036"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..439
                     /note="immunoglobulin light chain variable region"
     V_region        106..439
     V_segment       106..402
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69252.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       405..439
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           88 a          156 c          128 g          105 t
ORIGIN      
        1 acatggggat tcctggctgt ggctcaggaa gcagagcctg gagcgtctcc accatggcct
       61 gggctccact cctcctcacc ctcctcgctc acagggtctt gggctgaggt tctgttcacg
      121 cagccccatt ctgtgtcggg gtctccgggg cagacggtca ccatctcctg tatccgcagc
      181 agaggcaaca ttgacaatag ttatgtgcag tggtaccagc agcgcccggg cagtgccccg
      241 accacagtga tttacagaga taaccaaaga gcctctgggg tccctgatcg gttctctggc
      301 tccatcgaca gctcctccaa ctctgcctcc ctcaccatct ctgggctgaa gtctgaggac
      361 gaggctgact actactgtca gtctactgat ggcaactaca atcggttatt cggaggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003515             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:21971:3413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003515
VERSION     KCWK01003515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:21971:3413"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69253.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          152 c          120 g          111 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctgtg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003516             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:12191:22568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003516
VERSION     KCWK01003516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12191:22568"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..434
                     /note="immunoglobulin light chain variable region"
     V_region        86..434
     V_segment       86..395
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69254.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       400..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          158 c          111 g          113 t
ORIGIN      
        1 acatgggggg aaagaggctg tgtccaccat ggcctggact cctctcctcc tcctgctcct
       61 ctctcactgc acaggttccc tctcccagcc tgtgctgacc cagccaacct ccctctcagc
      121 atctccggga gcatcagtca gactcagctg caccttgagc agtggcatca atgttggttc
      181 ttacaccata ttctggtacc agcagaagcc agggagtcct ccccggttcc ttctgtacta
      241 ctactcagac tcaaataatc accagggctc tggagtcccc agccgcttct ctggatccaa
      301 agatgcttca gccaatgcag ggcttttact gatctctggg ctccagtctg aagatgaggc
      361 tgactattac tgtgccatgt ggcacagcag cgcttatgcc ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003517             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:14512:7769
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003517
VERSION     KCWK01003517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14512:7769"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69255.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           89 a          147 c          129 g           97 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct ccgatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtaaga gtgtgcactg gtaccaacac aagccaccgc aggcccctat cctggtcatc
      241 tattattata ccgaacggcc ctcggcgatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acactactat tgatcatggc tttttcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003518             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:22462:3021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003518
VERSION     KCWK01003518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22462:3021"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69256.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       403..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          157 c          122 g          107 t
ORIGIN      
        1 acatgggggc tgggatctca cgaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtggccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag gccggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttgttcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003519             364 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:4825:18233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003519
VERSION     KCWK01003519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 364)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4825:18233"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..323
                     /note="immunoglobulin light chain variable region"
     V_region        8..323
     V_segment       8..289
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <257..>298
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69257.1"
                     /translation="DYYCAIGLSSGYIF"
     J_segment       290..323
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        324..>364
                     /gene="IGLC"
BASE COUNT           76 a          113 c           94 g           81 t
ORIGIN      
        1 acatgggctc tcagcatctc ctggagcatc agccagtctc acatgtacct tcagcggtgg
       61 catcaatgtt gctggctacc acacacactg gtaccagcag aagccaggga ggcctccccg
      121 gtatcttctg agatacaaat cagactcaga taggggccag ggctctggag tccccagccg
      181 cttctctgga tccaaagatg tttcagcgaa cacagggatt ttacgcatct ctgggctcca
      241 gtctgaggat gaggctgact attactgtgc cattgggctc agcagcggtt acatcttcgg
      301 tactgggacc cggctcaccg tcccaggtca gcccaaggct tcccccacgg tcactctgtt
      361 cccg
//
LOCUS       KCWK01003520             272 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:10042:5509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003520
VERSION     KCWK01003520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 272)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 272)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..272
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10042:5509"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..234
                     /note="immunoglobulin light chain variable region"
     V_region        7..234
     V_segment       7..194
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <156..>206
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69258.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       198..234
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        235..>272
                     /gene="IGLC"
BASE COUNT           52 a           82 c           80 g           58 t
ORIGIN      
        1 acatggggta ccagcagagg ccaccgcagg cccctgtgct ggtcatctat gctgattatg
       61 aacggccctc agggatccct gaccgattct ctggctccaa gtcagggaac acggccaccc
      121 tgaccatcag cggagtcgag gccggggatg aggctgacta ttattgtcag gtgtgggaca
      181 tttatattga ccatccggtg ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      241 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003521             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:20981:9641
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003521
VERSION     KCWK01003521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20981:9641"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69259.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           92 a          164 c          122 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaagc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003522             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:21491:19887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003522
VERSION     KCWK01003522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21491:19887"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69260.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          163 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atttactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgcg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt ggtcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003523             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:10015:8593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003523
VERSION     KCWK01003523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10015:8593"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..455
                     /note="immunoglobulin light chain variable region"
     V_region        125..455
     V_segment       125..416
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69261.1"
                     /translation="DYYCQSYDSSLIVVLF"
     J_segment       418..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           95 a          157 c          123 g          118 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac ttcacagttc cagggtcctg
      121 ggcccagtct gtgctgacgc agccgccctc aatctctggg gcgcccgggc agagggtcac
      181 catctcctgc actgggagca gctccaacat tggagattat tttgtgcagt ggtaccagca
      241 ccttccagga acggccccca aacttctcat ctatgaaaat aataagcgac cctcagggat
      301 ttctgatcga ttctctggct cccagtctgg aacctcagcc tccctgacca tcactggact
      361 ccagtctgag gatgaggctg attattactg ccagtcctat gacagcagtt tgattgttgt
      421 gttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01003524             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:4723:15994
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003524
VERSION     KCWK01003524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:4723:15994"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69262.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       399..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           85 a          150 c          137 g           95 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc ggcctcctat gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcccctgt gggggagaca
      181 acattggaac taaatatgtg cactggtacc agcagaagcc agcgcaggcc cctgtgttgg
      241 tcatctatgc tgataccaga cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggatatgag gctgactatt
      361 tctgtcaggt gtgggacgat agtagtgatc atccggtttt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003525             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:4487:18633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003525
VERSION     KCWK01003525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:4487:18633"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69263.1"
                     /translation="DYSCQIWDSESDYYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          148 c          129 g           98 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctttga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 cttggaatta aatttgtcca ctggtaccag cagaagccag cgcaggcccc tgttaaggtc
      241 atctatgctg atgacaaacg gccctcaggg atccctgaga gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattcc
      361 tgtcagattt gggacagtga gagtgattat tacatcttcg gtcctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003526             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:7212:5705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003526
VERSION     KCWK01003526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7212:5705"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69264.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          150 c          121 g          113 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcaggacac aggatcctgg gttcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatgtt gggtattata acgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 caaactcatg atttatgacg tcattaagcg gccctcaggg gtttctgatc gcttctctgg
      301 ctccaagtct ggcgacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag aaataatttt ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003527             282 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:18708:5964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003527
VERSION     KCWK01003527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 282)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18708:5964"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..244
                     /note="immunoglobulin light chain variable region"
     V_region        8..244
     V_segment       8..201
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <166..>216
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69265.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       207..244
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        245..>282
                     /gene="IGLC"
BASE COUNT           63 a           87 c           64 g           68 t
ORIGIN      
        1 acatgggatg tatcctggta ccagcagttc ccaggaacag cccccaaact cctcatctat
       61 gaaaataata agcgaccctc aggggtttct gaccgattct ctggctccaa gtctggtacc
      121 tcagcctccc tgaccatcac tggactccaa tctgaggatg aggctgatta ttactgctca
      181 gcatgggata gcagcctgag tattaattac atcttcggtg gtgggacccg gctcaccgtc
      241 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01003528             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15400:12605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003528
VERSION     KCWK01003528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15400:12605"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69266.1"
                     /translation="DYFCQVWDSISDHPLF"
     J_segment       217..251
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           60 a           86 c           84 g           59 t
ORIGIN      
        1 acatggggga actaaatatg tgcactggta ccagcagaag ccagcgcagg cccctgtgca
       61 ggtcatttat ggtgatacca aacggccctc agggatccct gagcgattct ctggctccaa
      121 ctcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      181 tttctgtcag gtgtgggaca gtattagtga tcatccctta ttcggaggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003529             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:4525:10689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003529
VERSION     KCWK01003529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4525:10689"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69267.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          164 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg acccagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003530             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:5771:13806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003530
VERSION     KCWK01003530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:5771:13806"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69268.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       392..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          142 c          136 g          100 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcgat ttcagtgtcc ccaggacaga cggccagggt cacctgtggg ggagacaaca
      181 tcggaggtga agttgtgaat tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tctatgctga tagcgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacgcggc caccctgacc atcagcgggg tcgaggccgg agatgaggct gactattact
      361 gtcaggtgtg ggaccttaat agtcatcatc tcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003531             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:12384:5280
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003531
VERSION     KCWK01003531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12384:5280"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69269.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          157 c          125 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggcggttata actatgtctc ctggtaccaa caacatccag acacagcccc
      241 caaactcatg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctgctcac atgcaggcag tgatattttc gtgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003532             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:17756:5129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003532
VERSION     KCWK01003532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17756:5129"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69270.1"
                     /translation="DYYCQVWDSSSDHVFF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          146 c          136 g           93 t
ORIGIN      
        1 acatggggct gggcctcagg aagcagcctt ggcggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcgg cctcctatga aatgactcag
      121 ccgcgctcag tgtctgtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attagaagta aaaatgtgaa ttggtaccag cagaagccac cgcaggcccc cgcgctggtc
      241 atctattatg atagcgaccg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtgatcat gtgtttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003533             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:22850:10111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003533
VERSION     KCWK01003533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:22850:10111"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..428
                     /note="immunoglobulin light chain variable region"
     V_region        107..428
     V_segment       107..392
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69271.1"
                     /translation="DYYCQVWDSSSEWVF"
     J_segment       393..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           92 a          144 c          136 g           94 t
ORIGIN      
        1 acatggggct gtctgggtct caggaggcag cattgacggt gcctcagcca tggcctggac
       61 ccttctcctc ctcggcctcc tcgcttactg cacagactct gcgacctcct atgaattgac
      121 tcaggcaccc tcagtgtcag cggcctcagg acagacggcc aggatcacct gtgggggaga
      181 caacattgga agtaaaactg tgcactggta ccaacagaag gcagcgcagg cccctgtgct
      241 ggtcatcttt gctgatagca aacggccctc agggatccct gaccgattct ctggctccaa
      301 ctcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      361 ttactgtcag gtgtgggaca gtagtagtga atgggttttc ggcggaggga cccggctaac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003534             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:17126:12536
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003534
VERSION     KCWK01003534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17126:12536"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69272.1"
                     /translation="DYYCAIGHSSGYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           91 a          157 c          119 g          106 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggc tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagtggtggc atcaatgttg
      181 ctggctacca cacacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccagagatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtta catcttcggt gctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003535             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:11810:4190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003535
VERSION     KCWK01003535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11810:4190"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69273.1"
                     /translation="DYYCAAWDDGLRGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          152 c          120 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaacagtgtc gccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattatg atgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaggtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatgg cctgagaggt tacatcttcg gtgatgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003536             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:10326:13155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003536
VERSION     KCWK01003536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10326:13155"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69274.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          158 c          117 g          110 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 gtgtctacca catacactgg taccaactga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccagtaatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003537             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:9762:6554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003537
VERSION     KCWK01003537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9762:6554"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69275.1"
                     /translation="DYYCAAWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          159 c          122 g          108 t
ORIGIN      
        1 acatgggggc agcctcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtatcct ggtaccaaca actcccagaa
      241 acggctccca aactcctcat gtattataat catcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacttcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgaccggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003538             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:6328:11314
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003538
VERSION     KCWK01003538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6328:11314"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69276.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          129 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003539             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15544:7658
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003539
VERSION     KCWK01003539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15544:7658"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69277.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           90 a          147 c          128 g           97 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtcaaa gtgtacactg gtaccagcac aagccaccgc aggcccctgt tctggtcatc
      241 ttttattata ccgaacggcc ctcaggaatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acacaactat tgatcacggc ttgttcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003540             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:25809:9570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003540
VERSION     KCWK01003540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:25809:9570"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69278.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          101 a          137 c          123 g          105 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctggg gcctcctatg aggtgacaca
      121 gtcaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagcaat
      181 actggcaaat aattatgctc agtggttcca gcataagcca gaccaggccc ctgtgttggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gttgacagca gtgcccatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003541             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:8259:9854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003541
VERSION     KCWK01003541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8259:9854"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69279.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          156 c          127 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattat tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003542             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:2285:11852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003542
VERSION     KCWK01003542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:2285:11852"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69280.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          139 c          135 g          103 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003543             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:14347:16641
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003543
VERSION     KCWK01003543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14347:16641"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69281.1"
                     /translation="DYYCQSVDSSAHHPFF"
     J_segment       395..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          100 a          135 c          123 g          105 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagg tgacacagtc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagcaatact
      181 ggcaaataat tatgctcagt ggttccagca gaagccagac caggcccctg tgttggtgat
      241 atataaagac actgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacagtt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagtt gacagtagtg cccatcatcc gtttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003544             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:7444:4843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003544
VERSION     KCWK01003544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7444:4843"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..420
                     /note="immunoglobulin light chain variable region"
     V_region        90..420
     V_segment       90..384
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69282.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       385..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           80 a          155 c          119 g          104 t
ORIGIN      
        1 acatggggca gcgctctcgg gacgtctcca ccatggcctg ggctctgctc ctcctcaccc
       61 tcctcactca gggcacagga tcctgggctc agtctgccct gactcagcct ccctcagtgt
      121 ccaagtctct tggacagtcg gtcaccatct cctgcactgg aaccagcagt gacattggtg
      181 gttatgatgg cgtctcctgg taccagcagc actcagggac agcccccaga ctcctgattt
      241 atgatgtcac taagcggccc tcaggggtct cggatcgctt ctctggctcc aagtctggca
      301 acacggcctc cctcaccatc tctgggctcc agactgagga cgaggctgat tattactgtt
      361 gctcatatag gagtggaaac acttggctat tcggcggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003545             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:19485:14157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003545
VERSION     KCWK01003545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19485:14157"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69283.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          159 c          126 g          111 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccaggc
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcttgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003546             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:17573:17845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003546
VERSION     KCWK01003546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17573:17845"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..397
                     /note="immunoglobulin light chain variable region"
     V_region        76..397
     V_segment       76..361
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>369
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69284.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       365..397
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        398..>435
                     /gene="IGLC"
BASE COUNT           88 a          137 c          121 g           89 t
ORIGIN      
        1 acatggggtg cctcagccat ggcctggacc cttctcctcc tcggcctcct cgcttactgc
       61 acaggctctg cgacctccta tgaattgact cagtcaccct cagtgtcagc ggcctcagga
      121 cagccggcca ggatcacctg tgggggagac aacattggaa ctaaaactgt gcactggtac
      181 caacagaagc caccgcaggg ccctgtattg gtcatctttg ctgatagtag acggccctca
      241 gggatccctg agcgattctc tggctccaac tcagggaaca ccgccaccct gaccatcagc
      301 agggtcgagg ccggggatga ggctgactat tactgtcagg tgtgggacag tagtagtaaa
      361 tggatattcg gcggggggac ccggctaacc gtcctaggtc agcccaaggc tgccccctcg
      421 gtcactctct tcccg
//
LOCUS       KCWK01003547             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:21011:6934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003547
VERSION     KCWK01003547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21011:6934"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..394
                     /note="immunoglobulin light chain variable region"
     V_region        64..394
     V_segment       64..357
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <319..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69285.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       358..394
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>432
                     /gene="IGLC"
BASE COUNT           81 a          140 c          106 g          105 t
ORIGIN      
        1 acatgggggt ctcctctcct cctcaccctt ctcattcact tcacagttcc agggtcctgg
       61 gcccagtctg tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc
      121 atctcctgca ctgggagcag ctccaacatt ggagattatt ttgtgcagtg gtaccagcac
      181 cttccaggaa cggcccccaa actcctcatc tatgaaaata ataagcgacc ctcagggatt
      241 tctgatcgat tctctggctc ccagtctgga acctcagcct ccctgaccat cactggactc
      301 cagtctgagg atgaggctga ttattactgc cagtcctatg acagcagttt gattgctgtg
      361 ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      421 actctcttcc cg
//
LOCUS       KCWK01003548             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:11195:8165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003548
VERSION     KCWK01003548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:11195:8165"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69286.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          152 c          123 g          114 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggttcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt ataacgctgt gtcttggtac caacagcatc caggcgaagc
      241 ccccaaactc ataatttttg acgtcattaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccggg ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagaaataat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003549             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:10424:15964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003549
VERSION     KCWK01003549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10424:15964"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69287.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       409..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           87 a          159 c          126 g          108 t
ORIGIN      
        1 acatggggga ttcctggctg tggctcagga agcagagcct ggagcatctc caccatggcc
       61 tgggctccac tcctcctcac cctcctcgct cactgcacag ggtcttgggc tgaggttgtg
      121 ttcactcagc cccattctgt gtcggggtct ccggggcaga cggtcaccat ctcctgcacc
      181 cgcagcagtg gcagcattga caacggcttt gtgtactggt accagcagcg gccgggcagc
      241 gctcccacca ctgtgattta caaagataac caaagaccct ctggggtccc tgatcggttc
      301 tctggctcca tcgacagctc ctccaactct gcctccctca ccatctctgg actgaaatct
      361 gaggacgagg ctgactatta ctgtcagtct tatgacagca gcagtgtatt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003550             282 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:12681:4571
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003550
VERSION     KCWK01003550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 282)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12681:4571"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    15..244
                     /note="immunoglobulin light chain variable region"
     V_region        15..244
     V_segment       15..209
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <172..>216
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69288.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       214..244
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        245..>282
                     /gene="IGLC"
BASE COUNT           59 a           88 c           70 g           65 t
ORIGIN      
        1 acatgggatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc caaactcatg
       61 atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg ctccaagtct
      121 ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc tgattattac
      181 tgcagctcat atgcaggcag caacacttta ttcttcggag gagggacccg gctgaccgtc
      241 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003551             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:17772:18380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003551
VERSION     KCWK01003551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:17772:18380"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..262
                     /note="immunoglobulin light chain variable region"
     V_region        8..262
     V_segment       8..226
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>234
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69289.1"
                     /translation="YYYCSSYAGSHTYIF"
     J_segment       227..262
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        263..>300
                     /gene="IGLC"
BASE COUNT           56 a          100 c           72 g           72 t
ORIGIN      
        1 acatggggca gtgacatcgg tggttataac tatgtctcct ggttccagca gcaccccggc
       61 aaagccccca aactcatgat ttatgatgtc actcagcggc cctcaggggt ctctgatcgc
      121 ttctctggct ccaaatctgg ctacacggcc tccctgacca tctctgggct ccaggctgcg
      181 gatgaggctt attattactg cagctcatat gcgggcagcc acacttacat cttcggtact
      241 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003552             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:18112:15196
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003552
VERSION     KCWK01003552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18112:15196"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..435
                     /note="immunoglobulin light chain variable region"
     V_region        87..435
     V_segment       87..395
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69290.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       398..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           93 a          161 c          113 g          106 t
ORIGIN      
        1 acatgggggg gaaagaggct gtgtccacca tggcctggac tcctctcctc ctcctgctcc
       61 tctctcactg cacaggttcc ctctccaagc ctatgctgac tcagccggcc tccctctctg
      121 catctcctgg agcatcagcc agtctcacat gcaccttcag cggtggcatc aatgttgctg
      181 cctaccacat acactggtac cagcagaagc cagggagtcc tccccggtat cttctgagat
      241 acaaatcaga ctcagataag gaccagggct ctggagtccc cagccgcttc tctggatcca
      301 aagatgcctc agcgaacaca gggattttac gcatctctgg gctccagtct gaggatgagg
      361 ctgactacta ctgtgccatt gggcacagca gcggtgatta catcttcgct gctgggaccc
      421 gcctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003553             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:24367:10111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003553
VERSION     KCWK01003553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:24367:10111"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69291.1"
                     /translation="DYYCSSYAGRNSFLF"
     J_segment       400..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          158 c          121 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatgtt ggctattctc atgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 caaactcatg atttatgatg tcactaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaaggct ggcaacacgg cctccctcac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag gaactctttc ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003554             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:12405:11814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003554
VERSION     KCWK01003554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12405:11814"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..423
                     /note="immunoglobulin light chain variable region"
     V_region        101..423
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69292.1"
                     /translation="HYYCQVWDISSEHVLF"
     J_segment       392..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>463
                     /gene="IGLC"
BASE COUNT           83 a          144 c          136 g          100 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagc ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacgt
      181 tggaggtgat gttgtgaatt ggtaccacca gaagccaccg caggcccctg tcctggtcat
      241 ccatgctgat accgatcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc acccttacca tcagcggggt cgaggccggg gatgaggctc actattactg
      361 tcaggtgtgg gacattagta gtgagcatgt tttattcgga ggagggaccc ggctgaccgt
      421 cctgggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003555             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:10427:9886
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003555
VERSION     KCWK01003555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10427:9886"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69293.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          152 c          116 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgttgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta ataatgtgtc ctggtaccag cacctcccag gaacagctcc caaactcctc
      241 atctattata atgatcaacg aggctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcgt gggatgatag cctgagcagt tacatcttcg ctgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003556             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:4479:14134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003556
VERSION     KCWK01003556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4479:14134"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..252
                     /note="immunoglobulin light chain variable region"
     V_region        8..252
     V_segment       8..216
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <180..>224
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69294.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       220..252
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        253..>290
                     /gene="IGLC"
BASE COUNT           64 a           84 c           83 g           59 t
ORIGIN      
        1 acatgggcat tggaactaaa actgtacact ggtaccagca gaagccaccg cagggccctg
       61 tattggtcat ctttgctgat agtaaacggc cctcagggat ccctgagcga ttctctggct
      121 ccaactcagg gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg
      181 actattactg tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc
      241 taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003557             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:11801:19536
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003557
VERSION     KCWK01003557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11801:19536"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69295.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       411..447
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          158 c          128 g          111 t
ORIGIN      
        1 acatgggggc gcagcttcag ctgtgggtac agaaggcagg actcaggaca atctccagca
       61 tggcctggtt ccctctcgtc ctcaccctcc tcactcactg tgcagggtcc tgggcccagt
      121 ctgtgctgac tcagcctccc tcagcgtctg aggccgccag gaagagtgtc tccatctcct
      181 gttctggaag cagctccaac atcggaagtc atagtgtctc ctggtaccag cagctcccag
      241 gaacagctcc caaactcctc atctattata gtgatcaacg agcctcaggt gtctctgacc
      301 gattctctgg ctctcagtct ggcacgtcag cctccctggc catcagtggg ctccaggccg
      361 aggatgaggc tgattattac tgcgcagcat gggatgatag tctgagcggt tacatcttcg
      421 gtgctgggac ccggctcgcc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt
      481 tcccg
//
LOCUS       KCWK01003558             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:7734:24328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003558
VERSION     KCWK01003558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7734:24328"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..450
                     /note="immunoglobulin light chain variable region"
     V_region        117..450
     V_segment       117..413
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69296.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       414..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           87 a          163 c          132 g          106 t
ORIGIN      
        1 acatgggtgg cagtgtggct gcctcagcag agccctgagg agtctgcacc atggcctgga
       61 ccccaatcct cctcctcctc ctcactctcc tccttcactg cacagggtct ctctcccagc
      121 ctgtgctgac tcagtcgccc tctgcctctg cctccctggg agcctcggtc aagttcacct
      181 gcactctgag cagtggacac aggagctaca ccatcgcgtg gcatcagcag cagcaaggga
      241 aggcccctcg atacttgatg tggcttaaaa gtgatggcag ccacagcaag ggggacggga
      301 tccctgatcg cttctcaggc tccagctccg gggctgagcg ctacctcacc atctccaacc
      361 tccagtctga ggatgaggct gattattatt gtcagacgtg ggatattggc atttgggtgt
      421 tcggcggagg gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01003559             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:23618:11477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003559
VERSION     KCWK01003559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23618:11477"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    150..278
                     /note="immunoglobulin light chain variable region"
     V_region        150..278
     V_segment       150..242
                     /gene="IGLV2-118"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <206..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69297.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       243..278
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>316
                     /gene="IGLC"
BASE COUNT           52 a          109 c           86 g           69 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtctggcaac acggcctccc tcaccatctc
      181 tgggctccag actgaggacg aggctgatta ttactgttgc tcatatagga gtggaaacac
      241 ttggctattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      301 ggtcactctc ttcccg
//
LOCUS       KCWK01003560             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:19308:12814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003560
VERSION     KCWK01003560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:19308:12814"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69298.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          143 c          133 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga attgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattcgctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003561             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:14212:17370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003561
VERSION     KCWK01003561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14212:17370"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..263
                     /note="immunoglobulin light chain variable region"
     V_region        4..263
     V_segment       4..225
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <188..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69299.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       227..263
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           66 a           91 c           84 g           60 t
ORIGIN      
        1 acatggggga gacaacattg gaagtcaaag tgtgcactgg taccagcaca agccaccgca
       61 ggcccctgtt ctggtcatct tttattatac cgaacggccc tcaggaatcc ctgagcgaat
      121 ctctggctcc aaatcaggga acaccgccac cctgaccatc agcggggtcg aggccgggga
      181 tgaggctgac tattactgtc aggtgtggga cacaagtctt gatcacggct tattcggagg
      241 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01003562             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:22882:12364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003562
VERSION     KCWK01003562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22882:12364"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69300.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          165 c          125 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaagac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgtg ttaccactcc gactcagaca ggcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggacacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003563             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:8336:17032
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003563
VERSION     KCWK01003563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8336:17032"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..279
                     /note="immunoglobulin light chain variable region"
     V_region        7..279
     V_segment       7..240
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69301.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       245..279
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>317
                     /gene="IGLC"
BASE COUNT           64 a           96 c           78 g           79 t
ORIGIN      
        1 acatgggtgg catcaatgtt ggttcttaca ccatattctg gtaccagcag aagccaggga
       61 gtcctccccg gttccttctg tactactact cagactcaaa taatcaccag ggctctggag
      121 tccccagccg cttctctgga tccaaagatg cttcagccaa tgcagggctt ttactgatct
      181 ctgggctcca gtctgaagat gaggctgact attactgtgc catgtggcac agcagcgctt
      241 atgccttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct
      301 cggtcactct cttcccg
//
LOCUS       KCWK01003564             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:9064:14482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003564
VERSION     KCWK01003564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:9064:14482"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69302.1"
                     /translation="DYYCSAWDSSLTGGLF"
     J_segment       407..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           97 a          156 c          123 g          106 t
ORIGIN      
        1 acatggggca gcttcagctg tggctagaga agacaggact caggacaatc tccagcatgg
       61 cctgcttccc tctcatcctc accgtcctca ctcactgtgc aggatcctgg gcccagtctg
      121 tgctgactca accaccctca gcgtctgggg cccccgggca gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaatt atgtatactg gtaccagcag ttctcaggga
      241 aggcccccaa actcctcatc cataataata atcagcgacc ctcaggggtc cctgatcgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagtccgagg
      361 atgaggctga ttattactgc tcagcatggg atagcagtct gaccggtggc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003565             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:13653:5395
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003565
VERSION     KCWK01003565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13653:5395"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69303.1"
                     /translation="DYYCQVWDISSDHVLF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          140 c          138 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctccgcggcc tcctttgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa cttgtgaact ggtaccaaca gaggccaccg caggcccctg tgctggccat
      241 gtatgctgat agcgagcggc cctcagggat ccctgaacga ttctctggct ccaaatcagg
      301 gaatacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattagta gtgatcatgt gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003566             263 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:7147:13869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003566
VERSION     KCWK01003566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 263)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 263)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..263
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7147:13869"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..225
                     /note="immunoglobulin light chain variable region"
     V_region        6..225
     V_segment       6..186
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <156..>197
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69304.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       188..225
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        226..>263
                     /gene="IGLC"
BASE COUNT           48 a           79 c           73 g           63 t
ORIGIN      
        1 atggggggag cgctcccagg ttattcctgt actactactc cgactcagac aagcagctgg
       61 gacctggggt ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgtttt
      121 tgctcatctc tgggctccag cctgaggacg aggccgatta tttctgccag gtgtttgaca
      181 gtagtgttgt gttcttcgga ggagggaccc gactgaccgt cctaggtcag cccaaggctg
      241 ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003567             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:8646:18325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003567
VERSION     KCWK01003567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8646:18325"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69305.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           93 a          160 c          110 g          110 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacaacat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt gctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003568             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:11488:13178
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003568
VERSION     KCWK01003568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:11488:13178"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..442
                     /note="immunoglobulin light chain variable region"
     V_region        95..442
     V_segment       95..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69306.1"
                     /translation="DYYCAIGHSSGNYIF"
     J_segment       409..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           91 a          156 c          120 g          113 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagccta tgctgactca gccggcctcc
      121 ttctcagcat ctcctggagc ttcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctggct accacataca ctggtaccag cagaagccag ggagtcctcc ccggtttctt
      241 ctgagataca agtcagactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaagg atgcttcagc gaacacagga attttacgca tctctgggct ccagtctgag
      361 gatgaggctg actattactg tgccattggg cacagcagcg gtaattatat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003569             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:19500:12853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003569
VERSION     KCWK01003569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19500:12853"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..443
                     /note="immunoglobulin light chain variable region"
     V_region        119..443
     V_segment       119..406
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69307.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       409..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT          103 a          141 c          131 g          106 t
ORIGIN      
        1 acatgggggg ggagcccagc tgtgctgtgg ttctaggagg aagagctctg ggtgtctcac
       61 catgacctgg accactgttc tgctcccctt tctcactctc tgcacaggct ctggggcctc
      121 ctatgaggtg acacagtcac cctcagtgtc agtgtcccca ggacagacgg ccaggatcac
      181 ctgctctgga gcaatactgg caaataatta tgctcagtgg ttccagcaga agccagacca
      241 ggcccctgtg ttggtgatat ataaagacac tgagaggccc tcagggatcc ctgagcgatt
      301 ctctagctcc agttcaggga caacaattac cttgaccatc agtggggccc aggcagaaga
      361 tgaggctgac tattactgtc aatcagttga cagcagtgcc catcatccgt tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01003570             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:14294:7644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003570
VERSION     KCWK01003570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:14294:7644"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69308.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          159 c          117 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 ctgcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacattgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatataaatc agactcagat aaggaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ctcagcgaac acggggcttt tgcacatctc tgggctccag tctgaggatg
      361 aggctgacta ctactgtgcc attgggcaca gcagcggtga ttacatcttc ggtgctggga
      421 cccgcctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003571             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:18710:19863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003571
VERSION     KCWK01003571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18710:19863"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69309.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       399..436
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           93 a          151 c          116 g          114 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcgcag cctgtgctga ctcagccaac ctccctctca
      121 gcttctcctg gagcatcagc cagactcacc tgcaccttga gcagtggcat cagtgttggt
      181 acttacagga tattctggta ccagcagagg ccagggagtc ctccccggta tcttctgaac
      241 caccacacag actcagataa acatcagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cggccaatgc agggattttg ctcatctctg ggctccagtc tgaggatgag
      361 gctgactatt actgtatgat ttggcacaac aatgcttatg tgttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003572             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15607:3880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003572
VERSION     KCWK01003572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15607:3880"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69310.1"
                     /translation="DYYCCSYRTGNSWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          158 c          127 g          107 t
ORIGIN      
        1 acatgggggc tggggtccca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac caacagcact cagggacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tattgttgct catataggac tggaaacagt tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003573             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:26800:10966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003573
VERSION     KCWK01003573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:26800:10966"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69311.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          141 c          135 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccacga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaggccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tattgatcat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttccag
//
LOCUS       KCWK01003574             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:24398:14525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003574
VERSION     KCWK01003574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24398:14525"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69312.1"
                     /translation="DYYCQVWDSTSDHVFF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          141 c          138 g           98 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 cgccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacgaca
      181 ttggaagtaa atatgtgcac tggtaccagc agaagccacc gcaggcccct gtgctggtca
      241 tctattatga tggcgaacgg ccctcaggga tccctgagcg attctctgac tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtact agtgatcatg tgtttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003575             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:11922:20893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003575
VERSION     KCWK01003575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11922:20893"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..389
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69313.1"
                     /translation="DYYCSSWESSLNWIF"
     J_segment       391..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          149 c          125 g          104 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctctcct
       61 tctcactctg ctggttcact gcacagggtc ctgggcccag tctgtgctga cgcagccgcc
      121 ctcagcatct ggggcccccg ggcagagggt taccatctcc tgcactggga gcagctccaa
      181 catcggggcg ggtttttatg tgtcctggta ccaacagttc cctggaacag cccccaaact
      241 cctcatctat gaaaataata agcgaccctc aggggtttct gaccgattct ctggctccaa
      301 gtctggttcc tcagcctccc tgaccatcac tggactccag tctgaggatg aggctgatta
      361 ttactgctca tcatgggaaa gcagcctgaa ttggatattc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003576             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:5575:15165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003576
VERSION     KCWK01003576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5575:15165"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69314.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          155 c          126 g          108 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa cagtgtcgcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtatcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatgatg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caggtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagaggttac atcttcggtg
      421 atgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01003577             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:8273:16031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003577
VERSION     KCWK01003577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:8273:16031"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69315.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          141 c          138 g          102 t
ORIGIN      
        1 acatgggggg cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003578             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:10767:15615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003578
VERSION     KCWK01003578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10767:15615"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69316.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          163 c          121 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgcc
      181 ctcagtgttg gtaataaaaa catgtactgg taccaacaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaactaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtttgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01003579             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:16432:15950
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003579
VERSION     KCWK01003579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16432:15950"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69317.1"
                     /translation="DYYCAMWHSSASYFF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           92 a          163 c          111 g          114 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca cctttagcag tggcatcaat
      181 gttggtagtt acagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
      241 ctctactact actcagactc aagtaaacac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatgcaggc cttttactga tctctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccatgtgg cacagcagcg cttcttactt cttcggtact
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003580             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:12987:7008
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003580
VERSION     KCWK01003580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12987:7008"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69318.1"
                     /translation="DYYCQMWGMTSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          143 c          140 g           95 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccaatga tctgactcag
      121 ccaccctcgg tgtcagagtc cccaggacag acggccagga tcacctgtgg gggagacaag
      181 attggaagtg aagttgtgat ctggtaccag cagaagccac cgcaggcccc tctgttggtc
      241 atctctggtg atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcagatgt ggggcatgac tagtgatcat ccggtattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003581             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:25141:9293
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003581
VERSION     KCWK01003581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:25141:9293"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    57..405
                     /note="immunoglobulin light chain variable region"
     V_region        57..405
     V_segment       57..365
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69319.1"
                     /translation="DYCCAIGHSSGDYIF"
     J_segment       368..405
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>443
                     /gene="IGLC"
BASE COUNT           84 a          149 c          106 g          104 t
ORIGIN      
        1 acatggggac tcctctcctc ctcctgctcc tctctcactg cacaggttcc ctctccaagc
       61 ctatgctgac tcagccggcc tccctctcag catctcctgg agcttcagcc agtctcacat
      121 gcaccttcag cggtggcatc aatgttgctg gctaccacat acactggtac cagcagaagt
      181 cagggagtcc tccccggtat cttctaagat acaaatcaga ctcagatcag ggccagggct
      241 ctggagtccc cagccgcttc tctggatcca aagatgcttc agcgaacacg gggattttac
      301 acgtctctgg gctccagtct gaggatgagg ctgactattg ctgtgccatt gggcacagca
      361 gcggtgatta catcttcggt gctgggaccc ggctcaccgt cctaggtcag cccaaggctt
      421 cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003582             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:18837:3449
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003582
VERSION     KCWK01003582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:18837:3449"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69320.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           88 a          143 c          127 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gaggtgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003583             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:8965:10617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003583
VERSION     KCWK01003583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:8965:10617"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69321.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           90 a          147 c          129 g           96 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtcaaa gtgtgcactg gtaccagcac aagccaccgc aggcccctgt tctggtcatc
      241 ttttattata ccgaacggcc ctcaggaatc cctgagcgaa tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acacaagtct tgatcacggc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003584             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:11139:8920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003584
VERSION     KCWK01003584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11139:8920"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69322.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          161 c          114 g          110 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc atcagtgttg
      181 gtacttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctgt
      241 actaccactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcaggtctgt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttgcatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003585             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:21821:18083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003585
VERSION     KCWK01003585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21821:18083"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69323.1"
                     /translation="DYYCQVWDTSIDHGLF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          146 c          126 g           96 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtgaggga gacaacattg
      181 gaagtcaaag tgtgcactgg taccagcaca agccaccgca ggcccctata ctggtcatct
      241 tttattatac cgaacggccc tcaggaatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cacaagtatt gatcacggct tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003586             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:14499:22821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003586
VERSION     KCWK01003586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14499:22821"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69324.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          148 c          129 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct cccaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003587             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:23921:6448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003587
VERSION     KCWK01003587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23921:6448"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..446
                     /note="immunoglobulin light chain variable region"
     V_region        101..446
     V_segment       101..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69325.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       409..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           86 a          162 c          125 g          111 t
ORIGIN      
        1 acatgggggg gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagcagtga
      181 cctcagtgtt ggtagtaaaa acatgtactg gtaccagcag aagccaggga gcgctcccag
      241 gttattcctg tactactact ccgactcaga caagcagctg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt atttctgcca ggtgtttgac agtagtgttg tgttcttcgg
      421 aggagggacc cgactgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01003588             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:9679:8560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003588
VERSION     KCWK01003588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9679:8560"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..432
                     /note="immunoglobulin light chain variable region"
     V_region        103..432
     V_segment       103..396
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69326.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       401..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>471
                     /gene="IGLC"
BASE COUNT           95 a          158 c          114 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagttcca gggtcctggg cccagtctgt gctgactcag
      121 ccaccctcag cgtctgggac tcccgggcag agtgtcacca tctcgtgctc tggaagcagc
      181 tccaacattg gaactaatta tgtatactgg taccaacacc tcccaggaac ggcccccaaa
      241 ctcctcatct attatagtaa tcagcgaccc ccaggggtcc ctgaccgatt ctctggctct
      301 aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga tgaggctgat
      361 tattactgtg cagcatggga taacagcctg accagtccgg tattcggagg agggacccgg
      421 ctgaccgtcc taagtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003589             321 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:7055:5821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003589
VERSION     KCWK01003589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 321)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:7055:5821"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..283
                     /note="immunoglobulin light chain variable region"
     V_region        8..283
     V_segment       8..234
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>255
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69327.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       246..283
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>321
                     /gene="IGLC"
BASE COUNT           70 a           93 c           92 g           66 t
ORIGIN      
        1 acatgggcgg ccaggatcac ctgtggggga gacaacattg gaattaaatt tgtccactgg
       61 taccagcaga agccagcgca ggcccctgtg aaggtcatct atgctgatga caaacggccc
      121 tcagggatcc ctgagagatt ctctggctcc aattcaggga acaccgccac cctgaccatc
      181 agcggggtcg aggccgggga tgaggctgac tattcctgtc aggtgtggga cagtgagact
      241 gattattaca tcttcggtac tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc
      301 cccacggtca ctctgttccc g
//
LOCUS       KCWK01003590             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:24420:8978
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003590
VERSION     KCWK01003590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:24420:8978"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69328.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       401..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          151 c          115 g          115 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcatctcc tggagcatca gccagactca cctgcacctt gagcagtggc ttcagtattg
      181 gtaattacag gatattctgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gctaccacac agactcagat atgcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgt ttcggccaat gcagggattt tactcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtatg atttggcaca acaatgctta ttgggtattc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003591             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13316:15962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003591
VERSION     KCWK01003591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13316:15962"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..432
                     /note="immunoglobulin light chain variable region"
     V_region        103..432
     V_segment       103..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69329.1"
                     /translation="DYYCTSFADSNSVSF"
     J_segment       402..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>471
                     /gene="IGLC"
BASE COUNT           86 a          162 c          118 g          105 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcgctct cgggacatct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 cctcactcag tgtctgggtc tcctggacag tcggtcacca tcttctgctc tggaaccagc
      181 agtgacatcg gtggttataa ctatgtctcc tggtaccaac aacatccagg cacagccccc
      241 aaactcatca tttatgaggt cactaagcgg ccctcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccaggctga ggacgaggct
      361 gattattact gcacctcctt tgcggacagc aacagtgtct cattcggaag agggacccgg
      421 ctgaccgtcc tacgtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003592             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:20353:8262
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003592
VERSION     KCWK01003592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20353:8262"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69330.1"
                     /translation="DYHCQVYDGSAVLF"
     J_segment       409..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           87 a          160 c          121 g          112 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag tagtgacctc
      181 agtgttggta gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgtact acttctccga ctcagacaag cagttgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttac tcatctctgg gctccagcct
      361 gaggacgagg ccgattatca ctgtcaggtg tatgacggta gtgctgtttt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003593             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:11163:23152
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003593
VERSION     KCWK01003593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11163:23152"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69331.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          148 c          129 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaaccccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003594             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:6587:13590
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003594
VERSION     KCWK01003594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:6587:13590"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..255
                     /note="immunoglobulin light chain variable region"
     V_region        7..255
     V_segment       7..218
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <186..>227
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69332.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       219..255
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        256..>293
                     /gene="IGLC"
BASE COUNT           57 a           89 c           85 g           62 t
ORIGIN      
        1 acatgggcag ctacaccatc gcatggcatc agcagcagca agggaaggcc cctcggttct
       61 tgatgtggct taagagtgat ggcagccaca ccaaggggga cggggtccct gatcgcttct
      121 caggctccag ctccggggct gagcgctacc tcaccatctc caacctccag tctgaggatg
      181 aggctgatta ttactgtcag acctgggata ttggcatttg ggtattcggc ggagggaccc
      241 ggctaatcgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003595             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:16270:9931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003595
VERSION     KCWK01003595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16270:9931"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..432
                     /note="immunoglobulin light chain variable region"
     V_region        99..432
     V_segment       99..395
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69333.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       396..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           83 a          163 c          122 g          102 t
ORIGIN      
        1 acatgggagc agagccctga ggagtctgca ccatggcctg gaccccaatc ctcctcctcc
       61 tcctcactct cctccttcac tgcacagggt ctctctccca gcctgtgctg actcagtcgc
      121 cctctgcctc tgcctccctg ggagcctcgg tcaagctcac ctgcactctg agcagtggcc
      181 actacagcta caccatcgca tggcatcagc agcagcaagg gaaggcccct cggttcttga
      241 tgtggcttaa gagtgatggc agccacacca agggggacgg ggtccctgat cgcttctcag
      301 gctccagctc cggggctgag cgctacctca ccatctccaa cctccagtct gaggatgagg
      361 ctgattatta ctgtcagacc tgggatattg gcatttgggt attcggcgga gggacccggc
      421 taatcgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003596             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:17388:13921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003596
VERSION     KCWK01003596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17388:13921"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..296
                     /note="immunoglobulin light chain variable region"
     V_region        8..296
     V_segment       8..257
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <221..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69334.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       259..296
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>334
                     /gene="IGLC"
BASE COUNT           69 a           99 c           86 g           80 t
ORIGIN      
        1 acatgggggg cagagggtca ccatctcctg cactgggagc agctccaaca ttggaggtta
       61 ttatgtgcag tggtaccagc agcttccagg aacggccccc aaactcctca tctatgaaaa
      121 tgataaacga ccctcagggg tttctgatcg attctctggc tcccagtctg attcctcagc
      181 ctccctgacc atcactggac tccagtctga ggatgaggct gattattact gccagtccta
      241 tgacagcagc ttgagtgttg tgttattcgg aggagggacc cggctgaccg tcctaggtca
      301 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003597             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:4191:9445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003597
VERSION     KCWK01003597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4191:9445"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..409
                     /note="immunoglobulin light chain variable region"
     V_region        79..409
     V_segment       79..371
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69335.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       373..409
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           87 a          151 c          107 g          102 t
ORIGIN      
        1 acatggggga caatctccag catggcctgg ttccctctcg tcctcaccct cctcactcac
       61 tgtgcagggt cctgggccca gtctgtgctg actcagcctc cctcagcgtc tgaggccgcc
      121 aggaagagtg tcaccatctc ctgttctgga agcacctcca acatcggaag caataatgta
      181 tcctggtacc agcagctccc aggaacagct cccaaactcc tcttttatta taatgatcaa
      241 cgagcctcag gtgtctctga ccgattctct tgccccaagt ctggcacgtc agcctccctg
      301 gccatcagtg ggctccagac cgaggatgag gctgattatt actgcgcagc atgggatgat
      361 aacctgagcg gctacatctt cggtgctggg acccggctca ccgtcctagg tcagcccaag
      421 gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01003598             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:6524:17340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003598
VERSION     KCWK01003598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:6524:17340"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69336.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          138 c          135 g          105 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggaaag acggccagga tcacctgtgg gggagacaat
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaatg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tattgatcat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003599             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:22405:3546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003599
VERSION     KCWK01003599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22405:3546"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..400
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69337.1"
                     /translation="DYYCCSYRSGPTWVF"
     J_segment       401..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           84 a          158 c          124 g          108 t
ORIGIN      
        1 acatggggct ggggtctcag gaggcagcgc tctcgggacg tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcagtc tgccctgact
      121 cagcctccct cagtgtccaa gtctcttgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgaca ttggtggtta taatggcgtc tcctggtacc aacaacactc agggacagcc
      241 cccaaactcc tgatttatga tgtgaataag cggccctcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccagac tgaggacgag
      361 gctgattatt actgctgctc atataggagt ggacccactt gggttttcgg cggagggacc
      421 cgcctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003600             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:19705:14904
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003600
VERSION     KCWK01003600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19705:14904"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..396
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69338.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       398..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           95 a          151 c          115 g          110 t
ORIGIN      
        1 acatggggtc tggagccagg gatcccttcc aatatcagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcacctgtgc ttccagcact
      181 ggagcagtca ccagtggtca ctctccacac tggttccagc agaaacctgg acaagccccc
      241 aagacactga tttataatac aaactacaga cactcctgga ctcctgcccg gttctcaggc
      301 tccctccttg ggggtaaagc tgccctgaca ctgtcaggtg cgcagcctga ggatgaggct
      361 gagtattatt gtttactata ctatagtggt gctcagctgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003601             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:9377:15123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003601
VERSION     KCWK01003601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9377:15123"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69339.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          162 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatattgg caataaaaac atgtactggt accagcagaa gccagggagc gctcccaagt
      241 tattcctgta ctactactcc gactcagaca tgcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003602             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:13465:13952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003602
VERSION     KCWK01003602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13465:13952"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69340.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          161 c          115 g          107 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 ctgcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatacaaatc agactcagat aaggaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ctcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ctactgtgcc attgggcaca gcagcggtga ttacatcttc gctgctggga
      421 cccgcctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003603             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:20903:11068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003603
VERSION     KCWK01003603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20903:11068"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69341.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       394..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          152 c          122 g          106 t
ORIGIN      
        1 acatgggggg tacagaaggc aggactcagg acaatctcca gcatggcctg gttccctctc
       61 gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc agtctgtgct gactcagcct
      121 ccctcagcgt ctgaggccgc caggaagagt gtctccatct cctgttctgg aagcagctcc
      181 aacatcggaa gtcatagtgt ctcctggtac cagcaagtcc caggaacagc tcccaaactc
      241 ctcatctatt atagtgatca acgagcctca ggtgtctctg accgattctc tggctctcag
      301 tctggcacgt cagcctccct ggccatcagt gggctccaga ccgaggatga ggctgattat
      361 tactgcgcag catgggatga tagcctgagg ggttacatct tcggtgctgg gacccggctc
      421 gccgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01003604             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:20506:12322
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003604
VERSION     KCWK01003604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20506:12322"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69342.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          159 c          117 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttggtgtcta ccacatacac tggtaccaac tgaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003605             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:21983:13527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003605
VERSION     KCWK01003605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:21983:13527"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69343.1"
                     /translation="DYYCQSSHSRVNHPFF"
     J_segment       396..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT          103 a          137 c          123 g          101 t
ORIGIN      
        1 acatggggtg tggttctagg aggaagacct ctgggtgtct caccatgacc tggaccactg
       61 ttctgctccc ctttctcact ctctgcacag gctctgaggc ctcctatgag ctgacacagc
      121 caccctcagt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagaaacac
      181 tggcaaaaaa atatgctcag tggttccagc agaagccagg ccaggcccct gtgttggtga
      241 tatataaaga cagtgagagg ccctcaggga tccctgagcg attctctagc tccagttcag
      301 ggacaacagt taccttgacc atcagtgggg cccaggcaga agatgaggct gactattact
      361 gtcaatcatc gcacagcagg gttaatcatc cgtttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003606             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:13080:18671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003606
VERSION     KCWK01003606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13080:18671"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69344.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          160 c          120 g          109 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcgtcaatg
      181 tgggtagtta cagcgtattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacca gtcagactca aggaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc tgttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccctatggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggttact ctgttcccg
//
LOCUS       KCWK01003607             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:7052:5546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003607
VERSION     KCWK01003607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:7052:5546"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69345.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          163 c          120 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca aacagctggg acctgggttc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003608             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:7679:10466
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003608
VERSION     KCWK01003608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7679:10466"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69346.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       414..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           92 a          157 c          124 g          115 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcacttcac agttccaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag attattttgt gcagtggtac cagcaccttc
      241 caggaacggc ccccaaactc ctcatctatg aaaataataa gcgaccctca gggatttctg
      301 atcgattctc tggctcccag tctggaacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagtttgatt gctgtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01003609             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:12781:9197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003609
VERSION     KCWK01003609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12781:9197"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..278
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69347.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       282..314
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           77 a          104 c          104 g           67 t
ORIGIN      
        1 acatgggcag tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg
       61 gggagacaac attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc
      121 tgtattggtc atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg
      181 ctccaactca gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc
      241 tgactattac tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg
      301 gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003610             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:2048:11997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003610
VERSION     KCWK01003610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:2048:11997"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69348.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          147 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003611             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:4911:14568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003611
VERSION     KCWK01003611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4911:14568"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69349.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          161 c          113 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcaactcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 gttacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaaaatgc ttcaacgaac gcaggcattt ttcacatctc tgggctccag tctgaggatg
      361 aggctgacta tttctgtgcc attggacaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003612             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10606:13201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003612
VERSION     KCWK01003612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10606:13201"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69350.1"
                     /translation="DYYCQVFDSSAVFF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003613             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10489:12742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003613
VERSION     KCWK01003613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10489:12742"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69351.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          155 c          119 g          107 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catacactgg taccagcaga agccagggag tcctccccga tatcttctga
      241 gatacaaatc ggactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagggaac acagggattt tacgcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtgcc atcggacaca gcagcggtga ttacatcttc ggtgctggga
      421 cccggctcag cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003614             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:5880:13637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003614
VERSION     KCWK01003614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5880:13637"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69352.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       388..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          147 c          119 g          103 t
ORIGIN      
        1 acatgggggg gctcagaagc agaactctgg gtcctctcca ccatggcctg gacccctccc
       61 ctgctcatcc tcctcactct ctgcacaggt tccgtggttt cctctgagct gactcaggag
      121 cctgcattgt ctgtggcctt gggacataca gtcaggatga cctgccaagg agacagcctc
      181 aaaacctatt atgcaagctg gtaccagcag aagccaggcc aggtccctgt gctggtcatc
      241 tatggtaaca actaccggcc ctcagggatc ccaggccgat tctctgtctc ctggtcagga
      301 aacacaggtt ccttgaccat cactgcgact caggtggaag atgaggctga ctattactgt
      361 aagtcctggg acagcagtgg tacccactac atcttcggtg gtgggacccg gctcaccgtc
      421 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01003615             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:21043:5227
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003615
VERSION     KCWK01003615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:21043:5227"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..403
                     /note="immunoglobulin light chain variable region"
     V_region        85..403
     V_segment       85..371
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>375
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69353.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       372..403
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        404..>441
                     /gene="IGLC"
BASE COUNT           86 a          138 c          121 g           96 t
ORIGIN      
        1 acatgggggc tctggggtgt ctccaccatg gcctggactc ctctctggct caccctcctc
       61 agtctttgca caggttctat ggtttcttct gagctgactc aggaccctgc agtgtctgtg
      121 gccttgggac agacagtcag gattacctgc caaggagaca gcctcagaag ctcttatgca
      181 agctggtacc aacagaggcc aggccaggcc cctgtgctgg tcgtctatgg taacagcaac
      241 cggccctcag ggatcccaga gcgattctct ggctcctact cacgaaacac agcttccttg
      301 accatcactg gggctcaggt ggaagatgag gctgactatt actgtgactc ctgggacagc
      361 agcggaaccc aattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      421 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003616             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:24308:20107
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003616
VERSION     KCWK01003616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:24308:20107"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69354.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          142 c          134 g          102 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaggccac cgcaggcccc tgtactggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003617             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:14980:11766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003617
VERSION     KCWK01003617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14980:11766"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69355.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          155 c          119 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggaacatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ttggctacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatacaaatc ggactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac gcagggattt tacgcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtga ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003618             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:10297:18067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003618
VERSION     KCWK01003618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10297:18067"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69356.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          154 c          119 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctgtgca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003619             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:24790:14117
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003619
VERSION     KCWK01003619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:24790:14117"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69357.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          144 c          140 g           92 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccagcg cacgcccctg tgctggtcat
      241 ctatgctaat agcgaacggc cctcagggat ccctgggcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg ggtgaggctg actattactg
      361 tcaggtgtgg gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003620             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:16409:17495
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003620
VERSION     KCWK01003620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16409:17495"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69358.1"
                     /translation="DYYCQSYDRSLNAVLF"
     J_segment       416..449
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           95 a          153 c          126 g          113 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg agcagctcca atattggaga ttattatgtg cagtggttcc agcagcttcc
      241 aggaacggcc cccatactcc tcatctatga aaataataag cgaccctcag gggcttccaa
      301 tcgattctct ggctcccagt ctggtacctc agcctcgctg accataagtg gactccagtc
      361 tgaggatgag gctgactatt actgccagtc ttatgacaga agcttaaatg ctgttttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01003621             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:8831:20128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003621
VERSION     KCWK01003621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8831:20128"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69359.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           92 a          143 c          130 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gactctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtgctggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgacgccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggttttat tcggaggagg gacccgactg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003622             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:23079:5058
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003622
VERSION     KCWK01003622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23079:5058"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69360.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          147 c          130 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc gactgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003623             285 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:21583:13102
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003623
VERSION     KCWK01003623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 285)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 285)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21583:13102"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..247
                     /note="immunoglobulin light chain variable region"
     V_region        8..247
     V_segment       8..210
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <175..>219
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69361.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       211..247
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        248..>285
                     /gene="IGLC"
BASE COUNT           58 a           91 c           70 g           66 t
ORIGIN      
        1 acatgggggt accagcagaa gccagggagt cctccccggt accttcttta ctactactca
       61 gactcaagta accaccagga ctctggagtc cccagccgct tctctggatc gaaagatgct
      121 tcagccaatg cagggctttt actgatctct gggctccagt ctgaagatga ggctgactat
      181 tactgtgcca catggcacag cagcgcttct tacatcttcg gtggtgggac ccggctcacc
      241 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003624             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:27852:14711
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003624
VERSION     KCWK01003624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:27852:14711"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69362.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           92 a          156 c          128 g          108 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aacagtgtcg ccatctcctg
      181 ttctggaagc agctccaaca tcggaagtca tagtgtatcc tggtaccagc agctcccagg
      241 aacagctccc aaactcctca tctattatga tgatcaacga gcctcgggtg tctctgaccg
      301 attctctggc tccaggtctg gcacgtcagc ctccctggcc atcagtgggc tccagaccga
      361 ggatgaggct gattattact gcgcagcatg ggatgatagc ctgagaggtt acatcttcgg
      421 tgatgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01003625             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:10428:10788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003625
VERSION     KCWK01003625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:10428:10788"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..384
                     /note="immunoglobulin light chain variable region"
     V_region        99..384
     V_segment       99..345
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <315..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69363.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       347..384
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>422
                     /gene="IGLC"
BASE COUNT           73 a          144 c          107 g           98 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccaggggtc cccaatcgag
      241 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      301 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      361 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      421 cg
//
LOCUS       KCWK01003626             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:18341:14998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003626
VERSION     KCWK01003626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18341:14998"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..289
                     /note="immunoglobulin light chain variable region"
     V_region        8..289
     V_segment       8..253
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69364.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       257..289
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           73 a           94 c           98 g           62 t
ORIGIN      
        1 acatgggcag gacagccggc caggatcacc tgtgggggag acaacattgg aactaaaact
       61 gtgcactggt accaacagaa gccaccgcag ggccctgtat tggtcatctt tgctgatagt
      121 agacggccct cagggatccc tgagcgattc tctggctcca actcagggaa caccgccacc
      181 ctgaccatca gcagggtcga ggccggggat gaggctgact attactgtca ggtgtgggac
      241 agtagtagta aatggatatt cggcgggggg acccggctaa ccgtcctagg tcagcccaag
      301 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003627             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:13886:15669
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003627
VERSION     KCWK01003627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:13886:15669"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..385
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69365.1"
                     /translation="DYYCQVWDSTSDHYIF"
     J_segment       391..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          151 c          134 g           95 t
ORIGIN      
        1 acatgggggc tgggtctcag gaggcagcat tgacggtgcc tcagccatgg cctggaccct
       61 tctcctcctc ggcctcctcg ctcactgcac aggctctgcg acctcctatg agctgactca
      121 gccaccctcg gtgtcagcgg cctcaggaca gacggccagg gtcacctgtg ggggagacaa
      181 cattggaact acgtttgtgc actggtacca gcagaatccg ccgcaggccc ctgtgcaggt
      241 cctctttgcg gataacaaat ggccctcagg gatccctgaa cgattctctg gctccaactc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta ctagtgatca ttacatcttc ggtggtggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003628             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:24234:10312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003628
VERSION     KCWK01003628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:24234:10312"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69366.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           88 a          164 c          112 g          112 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc accaatgttg
      181 gtagttacag cattttctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaact aagcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc atttggcaca gcagcgcttc ttgcatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003629             361 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:24508:8895
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003629
VERSION     KCWK01003629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 361)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24508:8895"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..323
                     /note="immunoglobulin light chain variable region"
     V_region        8..323
     V_segment       8..283
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <251..>295
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69367.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       286..323
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        324..>361
                     /gene="IGLC"
BASE COUNT           76 a          110 c           94 g           81 t
ORIGIN      
        1 acatggggca tctcctggag catcagccag tctcacatgc accttcagcg gtggcatcaa
       61 tgttgctggc taccacatac actggtacca gcagaagtca gggagtcctc cccggtatct
      121 tctaagatac aaatcagact cagatcaggg ccagggctct ggagtcccca gccgcttctc
      181 tggatccaaa gatgcttcag cgaacacggg gattttacac gtctctgggc tccagtctga
      241 ggatgaggct gactattact gtgccattgg gcacagcagc ggtgattaca tcttcggtgc
      301 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      361 g
//
LOCUS       KCWK01003630             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:18626:19352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003630
VERSION     KCWK01003630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:18626:19352"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69368.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg acctggggtc ccaaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003631             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:14432:12989
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003631
VERSION     KCWK01003631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14432:12989"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..440
                     /note="immunoglobulin light chain variable region"
     V_region        92..440
     V_segment       92..403
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69369.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       404..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           93 a          162 c          109 g          114 t
ORIGIN      
        1 acatgggact gcagggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc ccagcctgta ctgacccagc caacctccct
      121 ctcagcatct ccgggagcat cagccagact cagctgcacc ttgagcagtg gcatcaatgt
      181 tggtagttac agcgtattct ggtaccagca gaagccaggg agtcctcccc ggttccttct
      241 gtactactac tcagactcaa gtaaacacca gggctctgga gtccccagcc gcttctctgg
      301 atccaaagat gcttcggcca atgcaggcct tttactgatc tctaggctcc agtctgaaga
      361 tgaggctgac tattactgtg ccatatggca cagcagcgct tcttacttct tcggtactgg
      421 gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01003632             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:21930:13356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003632
VERSION     KCWK01003632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21930:13356"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69370.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          137 c          121 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtctgtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca acagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003633             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:7118:3761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003633
VERSION     KCWK01003633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7118:3761"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..454
                     /note="immunoglobulin light chain variable region"
     V_region        109..454
     V_segment       109..415
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69371.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       417..454
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           88 a          168 c          124 g          112 t
ORIGIN      
        1 acatgggggc ccaaccctgg gtctgtggcc tcagaggtag ccgtgtccac catggccctg
       61 actcctctcc tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg
      121 actcagccac cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg
      181 agcagtgacc tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc
      241 gctcccaggt tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc
      301 cccaatcgag tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct
      361 gggctccagc ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg
      421 ttcttcggag gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCWK01003634             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:10855:5037
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003634
VERSION     KCWK01003634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10855:5037"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69372.1"
                     /translation="DYYCHVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          160 c          123 g          113 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcactctg agcagtgacc
      181 tcagtgttgg tggtaaaagc atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgtt ctactactcc gactcagaca agcagttggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccgactgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003635             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:18587:4015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003635
VERSION     KCWK01003635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18587:4015"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69373.1"
                     /translation="DYYCQVYDSSANVVF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          160 c          126 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaag atgtactggt accagcagaa ggcagggagc gctcccaggt
      241 tatacctcta ctacgactcc gactcagaca agcagttggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagccttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtggtattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003636             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:16209:10577
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003636
VERSION     KCWK01003636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16209:10577"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69374.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          137 c          135 g          103 t
ORIGIN      
        1 atgggggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggaaagacgg ccaggatcac ctgtggggga gacaatattg
      181 gaagtgaagt tgtcaactgg taccagcaga agccaccgca ggcccctgtg gtggtcatct
      241 atgctgatta tgaacggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acacggccac cctgaccatc agcggagtcg aggccgggga tgaggctgac tattactgtc
      361 aggtttggga catttatatt gatcatccgg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003637             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:10381:17639
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003637
VERSION     KCWK01003637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10381:17639"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69375.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       399..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           96 a          153 c          110 g          115 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcgcag cctgtgctga ctcagccaac ctccctctca
      121 gcatctcctg gagcatcagc cagactcacc tgcaccttga acagtggcat cagtgttgct
      181 aattacagga tattctggta ccaccagaag ccagggagtc ctccccggta tcttctgaac
      241 taccacacag actcagatat tcaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cggccaatgc agggatttta ctcatctctg gactccagtc tgaggatgag
      361 gctgactatt actgtatgat ttggcacaac aatgcttatt gggttttcgg cggagggacc
      421 cggctaaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003638             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:7283:7872
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003638
VERSION     KCWK01003638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7283:7872"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69376.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          149 c          131 g           97 t
ORIGIN      
        1 acatggggcc gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccgatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta agagtgtgca ctggtaccag cacaagccac cgcaggcccc tatcctggtc
      241 atctattatt ataccgaacg gccctcggcg atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacactac tattgatcat ggctttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003639             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14870:3705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003639
VERSION     KCWK01003639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14870:3705"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..336
                     /note="immunoglobulin light chain variable region"
     V_region        8..336
     V_segment       8..301
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69377.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       306..336
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           75 a          118 c           93 g           88 t
ORIGIN      
        1 acatgggggc tgccccgact cagactccct ctgtgtccgg gtctcctgga cagtcggtca
       61 ccatctcctg cactggaacc agcagtgata ttgggtatta tcatgctgtg tcttggtacc
      121 aacatcatcc aggcaaagcc cccaaactca tgatttatga ggtcaataaa cggcccgcag
      181 gggtctctga tcgcttctct ggctccaagt ctggcaacac ggcctccctg accatctctg
      241 ggctccagac tgaggatgag gctgattatt actgcagctc atatgcaggc agcaacactt
      301 tattcttcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      361 tcactctctt cccg
//
LOCUS       KCWK01003640             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:7056:7878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003640
VERSION     KCWK01003640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7056:7878"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69378.1"
                     /translation="DYYCQSYDSSLIGVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           92 a          153 c          127 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggagatt attatgtgca gtggtatcag caccttccag
      241 gaacggcccc caaactgctc atctatgaaa ataataaacg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggaacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag tttgattggt gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003641             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:14772:14206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003641
VERSION     KCWK01003641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14772:14206"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..239
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>243
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69379.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       240..269
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>309
                     /gene="IGLC"
BASE COUNT           66 a           97 c           86 g           60 t
ORIGIN      
        1 acatggggga ttacctgcca aggagacagc ctcagaagct cttatgcaag ctggtaccaa
       61 cagaggccag gccaggcccc tgtgctggtc gtctatggta acaactaccg gccctcaggg
      121 atcccagagc gattctctgg ctcctactca cgaaacacag cttccttgac catctctggg
      181 gctcaggtgg aagatgaggc tgactattac tgtgactcct gggacagcag cggaacccaa
      241 ttcggaggag ggacccggct gaccgtcctg ggtcagccca aggctgcccc ctcggtcact
      301 ctcttcccg
//
LOCUS       KCWK01003642             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:19697:10597
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003642
VERSION     KCWK01003642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19697:10597"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    65..410
                     /note="immunoglobulin light chain variable region"
     V_region        65..410
     V_segment       65..373
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69380.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       374..410
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>448
                     /gene="IGLC"
BASE COUNT           86 a          152 c          107 g          103 t
ORIGIN      
        1 acatgggatg gccctgactc ctctcctcct cctgctcctc tctcactgca caggttccct
       61 ctcccagcct gtgctgactc agccaccctc cctgtctgca tccccgggag catcggccag
      121 actcccctgc accctgagca gtgacctcag tgttggtaat aaaaacatgt actggtacca
      181 acagaagcca gggagcgctc ccaggttatt cctgtactac tactccgact cagacaagca
      241 gctgggacct ggggtcccca atcgagtctc tggctccaag gagacctcaa ctaacacagc
      301 gtttttgctc atctctgggc tccagcctga ggacgaggcc gattattact gtcaggtgtt
      361 tgacagtagt gctgtgttat tcggaggagg gacccgactg accgtcctag gtcagcccaa
      421 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003643             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:21007:3397
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003643
VERSION     KCWK01003643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21007:3397"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69381.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       394..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          141 c          135 g          102 t
ORIGIN      
        1 acatgggagc ctgactttga gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactttac aggctctgtg gcctcctatg agttgcctca
      121 gccacgctca gtgtccgtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt aatagtgtgc attggtacca gcagaagcca ccgcgggccc ctgtattggt
      241 catctctgtt gatagcgaac ggccctcagg gatccctgag cgattctctg gttccagatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggataata tttataaata cgcggtattc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003644             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:14098:14691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003644
VERSION     KCWK01003644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:14098:14691"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..440
                     /note="immunoglobulin light chain variable region"
     V_region        92..440
     V_segment       92..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69382.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       403..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           93 a          162 c          114 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggcttgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc caagcctatg ctgactcagc cggcctccct
      121 ctctgcatct cctggagcat cagccagtct cacatgcacc ttcagcggtg gcatcaatgt
      181 tgctgcctac cacatacact ggtaccagca gaagccaggg agtcctcccc ggtatcttct
      241 gagatataaa tcagactcag ataacgacca gggctctgga gtccccagcc gcttctctgg
      301 atccaaagat gcctcagcga acacgggact tttgcgcatc tctgggctcc agtctgagga
      361 tgaggctgac tactactgtg ccattggaca cagcagcggt gattacatct tcggtgctgg
      421 gacccgcctc accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01003645             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:8572:21386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003645
VERSION     KCWK01003645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:8572:21386"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69383.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          161 c          123 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttct
      481 cg
//
LOCUS       KCWK01003646             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:24792:8027
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003646
VERSION     KCWK01003646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:24792:8027"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..296
                     /note="immunoglobulin light chain variable region"
     V_region        8..296
     V_segment       8..261
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69384.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       263..296
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>334
                     /gene="IGLC"
BASE COUNT           72 a           98 c           84 g           80 t
ORIGIN      
        1 acatggggga cagtcggtca ccatctcctg cactggaacc agcagtgatg ttgggtatta
       61 taacgctgtg tcttggtacc aacaacatcc aggcaaagcc cccaaactca tgatttatga
      121 cgtcattaag cggccctcag gggtctctga tcgcttctct ggctccaagt ctggcaacac
      181 ggcctccctg accatctctg ggctccaggc tgaggatgag gctgattatt actgcagctc
      241 atatgcaggc agaaataatt ttttattcgg aggagggacc cggctgaccg tcctaggtca
      301 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003647             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:8133:3899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003647
VERSION     KCWK01003647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:8133:3899"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..343
                     /note="immunoglobulin light chain variable region"
     V_region        13..343
     V_segment       13..306
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <268..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69385.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       307..343
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>381
                     /gene="IGLC"
BASE COUNT           71 a          121 c          102 g           87 t
ORIGIN      
        1 acatgggggg cccagtctgt gctgactcag cctccctcag cgtctgaggc cgccaggaag
       61 agtgtctcca tctcctgttc tggaagcagc tccaacatcg gaagtcatag tgtctcctgg
      121 taccagcagg tcccaggaac agctcccaaa ctcctcatct attatagtga tcaacgagcc
      181 tcaggtgtct ctgaccgatt ctctggctct cagtctggca cgtcagcctc cctggccatc
      241 agtgggctcc agaccgagga tgaggctgat tattactgcg cagcatggga tgatagcctg
      301 aggggttaca tcttcggtgc tgggacccgg ctcgccgtcc taggtcagcc caaggcttcc
      361 cccacggtca ctctgttccc g
//
LOCUS       KCWK01003648             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:6878:7598
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003648
VERSION     KCWK01003648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:6878:7598"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..456
                     /note="immunoglobulin light chain variable region"
     V_region        126..456
     V_segment       126..419
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69386.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       420..456
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           94 a          158 c          126 g          116 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca cttcacagtt ccagggtcct
      121 gggcccagtc tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca
      181 ccatctcctg cactgggagc agctccaaca ttggagatta ttttgtgcag tggtaccagc
      241 accttccagg aacggccccc aaactcctca tctatgaaaa taataagcga ccctcaggga
      301 tttctgatcg attctctggc tcccagtctg gaacctcagc ctccctgacc atcactggac
      361 tccagtctga ggatgaggct gattattact gccagtccta tgacagcagt ttgattgctg
      421 tgttattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      481 tcactctctt cccg
//
LOCUS       KCWK01003649             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:21555:18903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003649
VERSION     KCWK01003649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21555:18903"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..268
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <230..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69387.1"
                     /translation="DYYCQSYDGSVSAVLF"
     J_segment       269..305
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           65 a          104 c           92 g           82 t
ORIGIN      
        1 acatgggggg gcgcccgggc agagggtcac cctctcctgc actgggagca gctccaacat
       61 tggagattat tatgtgcagt ggtaccagca gcttccagga acggccccca aactcctcat
      121 ctatgaaaat aataagcgac cctcaggggt ttctgctcga ttctctggct cccagtctgg
      181 ttcctctgcc tccctgacca tcactggact ccagtctgac gatgaggctg attattactg
      241 tcagtcctat gatggcagtg tgagtgctgt gttattcgga ggagggaccc ggctgaccgt
      301 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003650             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:23078:18821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003650
VERSION     KCWK01003650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23078:18821"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69388.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          138 c          138 g          100 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 gcaccctcga tttcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atgtatgctg atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagtggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacatgaa tagtcatcat ctgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003651             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:19120:9342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003651
VERSION     KCWK01003651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19120:9342"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69389.1"
                     /translation="GYYCSSFADTNTGLI"
     J_segment       398..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           91 a          154 c          121 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctaca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagaccc
      241 caaattcatg atttatgagg tcagtcaacg gccctcaggg gtctctgatc gtatctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tggttattac tgcagctcat ttgcagatac caacactggc ttaatcggtg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003652             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:17604:15034
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003652
VERSION     KCWK01003652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17604:15034"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69390.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       417..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           94 a          156 c          124 g          111 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg acagagggtc accatttcct
      181 gcattagcag cagctccaac atcggggcgg cttattatgt atcctggtac caacagttcc
      241 caggaacagc ccccaaactc ctcatctttg aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtccct cagcctccct gaccatcact ggactccaat
      361 ctgaggatga ggctgattat tactgtttag catgggatac cagcctgaat tggatcttcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003653             326 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:16373:15618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003653
VERSION     KCWK01003653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 326)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16373:15618"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..288
                     /note="immunoglobulin light chain variable region"
     V_region        5..288
     V_segment       5..251
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <219..>260
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69391.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       252..288
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        289..>326
                     /gene="IGLC"
BASE COUNT           65 a          101 c           92 g           68 t
ORIGIN      
        1 acatgggcaa gctcacctgc actctgagca gtggccacta cagctacacc atcgcatggc
       61 atcagcagca gcaagggaag gcccctcggt tcttgatgtg gcttaagagt gatggcagcc
      121 acaccaaggg ggacggggtc cctgatcgct tctcaggctc cagctccggg gctgagcgct
      181 acctcaccat ctccaacctc cagtctgagg atgaggctga ttattactgt cagacctggg
      241 atattggcat ttgggtattc ggcggaggga cccggctaat cgtcctaggt cagcccaagg
      301 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003654             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:24894:6528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003654
VERSION     KCWK01003654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24894:6528"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69392.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       411..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           83 a          160 c          129 g          111 t
ORIGIN      
        1 acatgggggc tcattcctgg ctgtggctca ggaagcagag cctggagcat ctccaccatg
       61 gcctgggctc cactcctcct caccctcctc gctcactgca cagggtcttg ggctgaggtt
      121 gtgttcactc agccccaatc tgtgtcgggg tctccggggc agacggtcac catctcctgc
      181 acccgcagca gtggcagcat tggcaacagc tatgtgtact ggttccagca gcggccgggc
      241 agcgtcccca ctattgtgat ttacaaagat gaccaaagac cctctggggt ccctgatcgg
      301 ttctctggct ccatcgacag ctcctccaac tctgcctccc tcaccatctc tggactgaag
      361 tctggggacg aggctgacta ttactgtcag tcttttgaca gcagcagtgt cttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01003655             353 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:8230:9464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003655
VERSION     KCWK01003655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 353)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8230:9464"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..315
                     /note="immunoglobulin light chain variable region"
     V_region        8..315
     V_segment       8..278
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>287
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69393.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       281..315
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        316..>353
                     /gene="IGLC"
BASE COUNT           71 a          107 c           96 g           79 t
ORIGIN      
        1 acatgggggg agcatcagcc agactcagct gcaccttgag cagtggcgtc aatgtgggta
       61 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctgtact
      121 accagtcaga ctcaaggaag caccagggct ctggagtccc cagccgcttc tctggatcca
      181 aagatgcttc agccaatgca gggctgttac tgatctctgg gctccagtct gaagatgagg
      241 ctgactatta ctgtgcccta tggcacagca gcgcttcttg catcttcggt ggtgggaccc
      301 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003656             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:7959:11806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003656
VERSION     KCWK01003656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7959:11806"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..436
                     /note="immunoglobulin light chain variable region"
     V_region        90..436
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69394.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           92 a          161 c          109 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt tagtagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc gatactggga
      421 cccggctcac cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003657             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:12861:14044
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003657
VERSION     KCWK01003657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12861:14044"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69395.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       398..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          164 c          123 g          102 t
ORIGIN      
        1 acatggggca gcagagccct gaggagtctg caccatggcc tggaccccaa tcctcctcct
       61 cctcctcact ctcctccttc actgcacagg gtctctctcc cagcctgtgc tgactcagtc
      121 gccctctgcc tctgcctccc tgggagcctc ggtcaagctc acctgcactc tgagcagtgg
      181 ccactacagc tacaccatcg catggcatca gcagcagcaa gggaaggccc ctcggttctt
      241 gatgtggctt aagagtgatg gcagccacac caagggggac ggggtccctg atcgcttctc
      301 aggctccagc tccggggctg agcgctacct caccatctcc aacctccagt ctgaggatga
      361 ggctgattat tactgtcaga cctgggatat tggcatttgg gtattcggcg gagggacccg
      421 gctaatcgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003658             517 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:27477:8459
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003658
VERSION     KCWK01003658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 517)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:27477:8459"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    149..479
                     /note="immunoglobulin light chain variable region"
     V_region        149..479
     V_segment       149..438
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <404..>451
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69396.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       442..479
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        480..>517
                     /gene="IGLC"
BASE COUNT          107 a          157 c          138 g          115 t
ORIGIN      
        1 acatggggag agtatgaaga gagggagaga tttgggtgaa gcgcagcttc agctgtgggt
       61 acagaaggca ggactcagga caatctccag catggcctgg ttccctctcg tcctcaccct
      121 cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagcctc cctcagcgtc
      181 tgaggccgcc aggaagagtg tcaccatctc ctgttctgga agcagctcca acatcggaag
      241 taataatgtg tcctggtacc agcacctccc aggaacagct cccaaactcc tcatctatta
      301 taatgatcaa cgaggctcag gtgtctctga ccgattctct ggctccaagt ctggcacgtc
      361 agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt actgcgcagc
      421 gtgggatgat agcctgagta gttacatctt cgctgctggg acccggctca ccgtcctagg
      481 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01003659             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:14882:9559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003659
VERSION     KCWK01003659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14882:9559"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69397.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          153 c          122 g          110 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat tatgctgtgt cttggtacca gcatcatcca ggcaaagccc
      241 ccaagctcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003660             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:15971:23819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003660
VERSION     KCWK01003660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15971:23819"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..431
                     /note="immunoglobulin light chain variable region"
     V_region        99..431
     V_segment       99..392
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69398.1"
                     /translation="DYYCAAWDDSLSGYYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>470
                     /gene="IGLC"
BASE COUNT           92 a          153 c          118 g          107 t
ORIGIN      
        1 acatgggggt acagaaggca ggactcagga caatctccag catggcctgg ttccctctcg
       61 tcctcaccct cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagcctc
      121 cctcagcgtc tgaggccgcc aggaagagtg tcaccatctc ctgttctgga agcagctcca
      181 acatcggaag taatagtgtg tcctggtacc agcaactccc aggaacgcct cccaaactcc
      241 tcatctattt taatgatcag cgagcctcag gtgtctctga ccgattctct ggctccaagt
      301 ctggcacgtc agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt
      361 actgcgcagc atgggatgat agcctgagcg gttattacat cttcggtgct gggacccggc
      421 tcaccgtcct aagtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003661             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:14456:6872
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003661
VERSION     KCWK01003661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14456:6872"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69399.1"
                     /translation="DYYCQVYDSSAGVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          163 c          124 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 cattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctggt gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003662             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:15109:11016
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003662
VERSION     KCWK01003662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15109:11016"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..393
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <357..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69400.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       394..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           80 a          154 c          125 g          108 t
ORIGIN      
        1 acatggggtg gggtctcagg aggcagcgct ctcgggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggat cctgggctca gtctgccctg actcagcctc
      121 cctcagtgtc caagtctctt ggacagtcgg tcaccatctc ctgcactgga accagcagtg
      181 acattggtgg ttatgatggc gtctcctggt accagcagca ctcagggaca gcccccagac
      241 tcctgattta tgatgtcact aagcggccct caggggtctc ggatcgcttc tctggctcca
      301 agtctggcaa cacggcctcc ctcaccatct ctgggctcca gactgaggac gaggctgatt
      361 attattgttg ctcatatagg agtggaaaca cttggctatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003663             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:19307:17065
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003663
VERSION     KCWK01003663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19307:17065"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69401.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          166 c          123 g          107 t
ORIGIN      
        1 acatgggggg gtccgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003664             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:11233:6169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003664
VERSION     KCWK01003664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:11233:6169"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69402.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          154 c          122 g          105 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtctccatc tcctgttctg gaagcagctc
      181 caacatcgga agtcatagtg tctcctggta ccagcagctc ccaggaacag ctcccaaact
      241 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctccaa
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgcg gcatgggatg atagcctgag cggttacatc ttcggtgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003665             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:26389:12225
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003665
VERSION     KCWK01003665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:26389:12225"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69403.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       408..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          161 c          117 g          108 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcgtcaat
      181 gtgggtagtt acagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
      241 ctgtactacc agtcagactc aaggaaacac cagggctctg gagtccccag ccacttctct
      301 ggatccaaag atgcttcagc caatgcagga ctattactga tctctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccctatgg cacagcagcg cttcttgcat cttcggtggt
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003666             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:17049:10287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003666
VERSION     KCWK01003666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17049:10287"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..455
                     /note="immunoglobulin light chain variable region"
     V_region        125..455
     V_segment       125..418
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69404.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       419..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           94 a          158 c          125 g          116 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac ttcacagttc cagggtcctg
      121 ggcccagtct gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac
      181 catctcctgc actgggagca gctccaacat tggagattat tttgtgcagt ggtaccagca
      241 ccttccagga acggccccca aactcctcat ctatgaaaat aataagcgac cctcagggat
      301 ttctgatcga ttctctggct cccagtctgg aacctcagcc tccctgacca tcactggact
      361 ccagtctgag gatgaggctg attattactg ccagtcctat gacagcagtt tgattgctgt
      421 gttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01003667             338 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:12057:7876
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003667
VERSION     KCWK01003667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 338)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12057:7876"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..300
                     /note="immunoglobulin light chain variable region"
     V_region        5..300
     V_segment       5..264
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <228..>272
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69405.1"
                     /translation="DYYCQVWDSSSEWVF"
     J_segment       265..300
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        301..>338
                     /gene="IGLC"
BASE COUNT           72 a           98 c          105 g           63 t
ORIGIN      
        1 acatggggtc agcggcctca ggacagacgg ccaggatcac ctgtggggga gacaacattg
       61 gaagtaaaac tgtgcactgg taccaacaga aggcagcgca ggcccctgtg ctggtcatct
      121 ttgctgatag caaacggccc tcagggatcc ctgaccgatt ctctggctcc aactcaggga
      181 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      241 aggtgtggga cagtagtagt gaatgggttt tcggcggagg gacccggcta accgtcctag
      301 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003668             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:9835:7667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003668
VERSION     KCWK01003668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9835:7667"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69406.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          147 c          129 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtcca ctgcacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccaaca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003669             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:12678:14038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003669
VERSION     KCWK01003669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12678:14038"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69407.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          161 c          113 g          113 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcatcaat
      181 gttggtagtt acagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
      241 ctgtactact actcagactc aagtaaacac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatgcaggc cttttagtga tctctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccatatgg cacagcagcg cttcttactt cttcggtact
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003670             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:20548:22193
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003670
VERSION     KCWK01003670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20548:22193"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..448
                     /note="immunoglobulin light chain variable region"
     V_region        119..448
     V_segment       119..412
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69408.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       417..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>487
                     /gene="IGLC"
BASE COUNT           96 a          162 c          120 g          109 t
ORIGIN      
        1 acatggggag cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gttccagggt cctgggccca
      121 gtctgtgctg actcagccac cctcagcgtc tgggactccc gggcagagtg tcaccatctc
      181 gtgctctgga agcagctcca acattggaac taattatgta tactggtacc aacacctccc
      241 aggaacggcc cccaaactcc tcatctatta tagtaatcag cgaccctccg gggtccctga
      301 ccgattctct ggctctaagt ctggcacctc agcctccctg gccatcactg gtctccgatc
      361 tgaggatgag gctgattatt actgtgcagc atgggataac agcctgacca gtccggtatt
      421 cggaggaggg acccggctga ccgtcctaag tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01003671             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:16372:20599
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003671
VERSION     KCWK01003671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16372:20599"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69409.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       400..435
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          154 c          122 g          110 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccagcatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacgcttt gttcttcgga ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003672             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:11900:7501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003672
VERSION     KCWK01003672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11900:7501"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69410.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          147 c          130 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtacact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca gcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttgttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003673             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:17167:11347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003673
VERSION     KCWK01003673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:17167:11347"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69411.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          148 c          138 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctggctcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta actatgtgca ctggtaccag cagaagccag cgcaggcccc tgtagagatt
      241 atctttgctg ataacaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggatcaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactatttc
      361 tgtcaggtgt ggggcagtcg tagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003674             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:19370:11514
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003674
VERSION     KCWK01003674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19370:11514"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69412.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          159 c          123 g          106 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caacaccatc caggcacagc
      241 ccccaaagtc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catatacagg catcaacagt tacatcttcg gtggtgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003675             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:12976:11304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003675
VERSION     KCWK01003675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12976:11304"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69413.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           98 a          143 c          121 g           98 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaagaatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tccagatcat
      241 ctatgaggac agtaaacggc cctctgggat ccctgagaga atctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 tttctcaaca gacaccagtg gtaatcgggt attcggcgga gggacccgtc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003676             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:20642:4424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003676
VERSION     KCWK01003676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20642:4424"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69414.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       408..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          157 c          116 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatatac tggtaccacc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctggactc cagtctgaag
      361 atgaggctga ctattactgt gccattggac acagcagcgg cgattatatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003677             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:19199:4820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003677
VERSION     KCWK01003677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19199:4820"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..390
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69415.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       391..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           82 a          161 c          122 g          100 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 actctcctcc ttcactgcac agggtctctc tcccagcctg tgctgactca gtcgccctct
      121 gcctctgcct ccctgggagc ctcggtcaag ctcacctgca ctctgagcag tggccactac
      181 agctacacca tcgcatggca tcagcagcag caagggaagg cccctcggtt cttgatgtgg
      241 cttaagagtg atggcagcca caccaagggg gacggggtcc ctgatcgctt ctcaggctcc
      301 agctccgggg ctgagcgcta cctcaccatc tccaacctcc agtctgagga tgaggctgat
      361 tattactgtc agacctggga tattggcatt tgggtattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003678             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:13354:14458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003678
VERSION     KCWK01003678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:13354:14458"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..418
                     /note="immunoglobulin light chain variable region"
     V_region        94..418
     V_segment       94..381
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <343..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69416.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       382..418
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>456
                     /gene="IGLC"
BASE COUNT           91 a          144 c          117 g          104 t
ORIGIN      
        1 acatggggag aagcagaact ctgggtcctc tccaccatgg cctggacccc tcccctgctc
       61 atcctcctca ctctctgcac aggttccgtg gtttcctctg agctgactca ggagcctgca
      121 ttgtctgtgg ccttgggaca tacagtcagg atgacctgcc aaggagacag cctcagaacc
      181 tattatgcaa gctggtacca gcagaagcca ggccaggtcc ctgtgttggt catctatggt
      241 aacaactacc ggccctcagg gatcccaggc cgattctctg tctcctggtc aggaaacaca
      301 ggttccttga ccatcactgc ggctcaggtg gaagatgagg ctgactatta ctgtaagtcc
      361 tgggacagca gtggtaccca ttacatcttc ggtgctggga cccggctcac cgtcctaggt
      421 cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003679             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:10243:15959
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003679
VERSION     KCWK01003679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:10243:15959"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69417.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           91 a          155 c          119 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctggac
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcagtggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcgtc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 agctgattat tactgcagct catatgcagg cagcaacact ttattcttcg gacgagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003680             295 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:6619:15007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003680
VERSION     KCWK01003680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 295)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:6619:15007"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..257
                     /note="immunoglobulin light chain variable region"
     V_region        8..257
     V_segment       8..208
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <182..>229
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69418.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       220..257
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>295
                     /gene="IGLC"
BASE COUNT           65 a           86 c           81 g           63 t
ORIGIN      
        1 acatgggaac attggaatta aatttgtcca ctggtaccag cagaagccag cgcaggcccc
       61 tgtgaaggtc atctatgctg atgacaaacg gccctcaggg atccctgaga gattctctgg
      121 ctccaattca gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc
      181 tgactattcc tgtcaggtgt gggacagtga gactgattat tacatcttcg gtactgggac
      241 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003681             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:25092:9280
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003681
VERSION     KCWK01003681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:25092:9280"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69419.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          157 c          120 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat gttgggtatt atcattctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacgct ttattcttcg gacgagggac
      421 ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003682             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18228:11194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003682
VERSION     KCWK01003682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18228:11194"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69420.1"
                     /translation="DYYGQSYDSSSVLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          157 c          125 g          104 t
ORIGIN      
        1 acatgggggc tgtggctcag gaagcagagc ctggagcatc tccaccatgg cctgggctcc
       61 actcctcctc accctcctcg ctcactgcac agggtcttgg gctgaggttg tgttcactca
      121 gccccattct gtgtcggggt ctccggggca gacggtcacc atctcctgca cccgcagcag
      181 tggcagcatt gacaacggct ttgtgtactg gtaccagcag cggccgggca gcgctcccac
      241 cactgtgatt tacaaagata accaaagacc ctctggggtc cctgatcggt tctctggctc
      301 catcgacagc tcctccaact ctgcctccct caccatctct ggactgaaat ctgaggacga
      361 ggctgactat tacggtcagt cttatgacag cagcagtgta ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003683             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:18435:9454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003683
VERSION     KCWK01003683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18435:9454"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69421.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          155 c          120 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgttggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcggactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagtg aacgcaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003684             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:8549:10200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003684
VERSION     KCWK01003684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8549:10200"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69422.1"
                     /translation="DYYCCSYTTDSTYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          163 c          115 g          110 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtccgtc accatctcct gcactggaac
      181 catcagtgac gttggtggtc ataactctgt ctcctggtac caacaccacc caggcaaacc
      241 ccccaaagtc atgacttatg gtgtcagtaa tcgggcctca ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgttgtt catatacaac cgatagcact tacatcttcg gtagtgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003685             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:6037:7525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003685
VERSION     KCWK01003685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:6037:7525"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..380
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69423.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       383..420
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           84 a          157 c          113 g          104 t
ORIGIN      
        1 acatgggggc ccccactgtg gggaaagagg ctgtgtccac catggcctgg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccaa gcctgtgctg actcagccgg
      121 cctccctctc tgcatctcct ggagcatcag ccagtctcac atgcaccttc agcggtggca
      181 tcaatgttgc tgcctaccac atacactggt accagcagaa gccagggagt cctccccggt
      241 ttcttctgag atataaatca gactcagata aggaccaggg ctctggagtc ccctcagcga
      301 acacggggct tttgcgcatc tctgggctcc agtctgagga tgaggctgac tactactgtg
      361 ccattggaca cagcagcggt gattacatct tcggtgctgg gacccgcctc accgtcctag
      421 gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01003686             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:23927:12601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003686
VERSION     KCWK01003686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23927:12601"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69424.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          161 c          121 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtaataaaaa catgtactgg taccaacaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaactaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cctaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01003687             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:7627:10334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003687
VERSION     KCWK01003687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7627:10334"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..380
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69425.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       392..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          148 c          133 g           96 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctccttt gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaat taaatttgtc cactggtacc agcagaagcc agcgcaggcc cctgtgaagg
      241 tcatctatgc tgatgacaaa cggccctcag ggatccctga gagattctct ggctccaatt
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 cctgtcaggt gtgggacagt gagactgatc attacatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01003688             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:5844:15233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003688
VERSION     KCWK01003688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:5844:15233"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..409
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69426.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       418..448
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           95 a          156 c          125 g          110 t
ORIGIN      
        1 acatgggggg aagctctgct tcagctgtgg gcacaggagg cagcactcag gacagtctcc
       61 agcatggcct ggtctctcct tctcactctg ctggttcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagcatct ggggcccccg gacagagggt caccatctcc
      181 tgcattagca gcagctccaa catcggggcg gcttattatg tatcctggta ccaacagtta
      241 ccaggaacag cccccaaact cctcatcttt gaaaataata agcgaccctc aggggtttct
      301 gaccgattct ctggctccaa gtctggtccc tcagcctccc tgaccatcac tggactccaa
      361 tctgaggatg aggctgatta ttactgttta gcatgggata ccagcctgaa ttggatcttc
      421 ggcggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01003689             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:7851:7325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003689
VERSION     KCWK01003689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7851:7325"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..432
                     /note="immunoglobulin light chain variable region"
     V_region        103..432
     V_segment       103..396
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69427.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       401..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>471
                     /gene="IGLC"
BASE COUNT           95 a          157 c          113 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactt tgcagttcca gggtcctggg cccagtctgt gctgactcag
      121 ccaccctcag cgtctgggac tcccgggcag agtgtcacca tctcgtgctc tggaagcagc
      181 tccaacattg gaactaatta tgtatactgg taccaacacc tcccaggaac ggcccccaaa
      241 ctcctcatct attatagtaa tcagcgaccc tcaggggtcc ctgaccgatt ctctggctct
      301 aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga tgaggctgat
      361 tattactgtg cagcatggga taacagcctg accagtccgg tattcggagg agggacccgg
      421 ctgaccgtcc taagtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003690             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22332:6953
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003690
VERSION     KCWK01003690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22332:6953"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..406
                     /note="immunoglobulin light chain variable region"
     V_region        86..406
     V_segment       86..370
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <335..>379
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69428.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       371..406
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>445
                     /gene="IGLC"
BASE COUNT           92 a          140 c          116 g           97 t
ORIGIN      
        1 acatggggag agctctgggt gtctcaccat ggcctggatt cctctcctac tccccatcct
       61 cactttctgc acaggctctg cagcctccta tgagctgaca cagccaccct cggtgtcagt
      121 gtccccagga cagacggcca agatcacctg ctctggagat gcactgccaa aaaaatatgc
      181 ttattggttc cagcagaagc caggccagtc ccctgtgttg atcatcgatg aggacaccaa
      241 acggccctct gggatccctg agagattctc tggctccagc tcagggacag tggccacctt
      301 gactatcagt ggggcccagg tggaggatga agctgactac tactgttact cagcagacag
      361 cagtggttat ggcttattcg gaggagggac ccggctgacc gtcctacgtc agcccaaggc
      421 tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003691             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:17755:7773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003691
VERSION     KCWK01003691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17755:7773"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69429.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           90 a          154 c          119 g          110 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003692             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:24714:18841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003692
VERSION     KCWK01003692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:24714:18841"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69430.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       388..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           98 a          143 c          122 g           98 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc catcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagaagaat
      181 tgccaaaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtccagatca
      241 tctatgagga cagtaaacgg ccctctggga tccctgagag aatctctggc tccagctcag
      301 ggacagtggc caccttgact atcactgggg cccaggtgga ggatgaagct gactactact
      361 gtttctcaac agacaccagt ggtaatcggg tattcggcgg agggacccgt ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003693             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:19948:13190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003693
VERSION     KCWK01003693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19948:13190"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69431.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          158 c          126 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaagtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003694             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:14457:18529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003694
VERSION     KCWK01003694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14457:18529"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69432.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          138 c          121 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003695             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:25162:8286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003695
VERSION     KCWK01003695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:25162:8286"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..240
                     /gene="IGLV3-35"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69433.1"
                     /translation="DYYCGSWDNSDKHYLF"
     J_segment       241..277
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>315
                     /gene="IGLC"
BASE COUNT           71 a           89 c           85 g           70 t
ORIGIN      
        1 acatggggga tgacctgcca aggagacagc ctcaaaacct attatgtaag ctggtaccag
       61 cagaagccag gccaggtccc tgtgctggtc atctatggta acaccaatag gccctcaggg
      121 atcccaggcc gattctctgg ctcatggtca ggaaactcag gttccttgac catcactggg
      181 gctcaggtgg aagatgaggc tgactattac tgtggctcct gggataacag tgataagcat
      241 tacctcttcg gtgatgggac ccggttcacc gtcctaggtc agcccaaggc ttcccccacg
      301 gtcactctgt tcccg
//
LOCUS       KCWK01003696             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:23664:11835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003696
VERSION     KCWK01003696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23664:11835"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69434.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          156 c          119 g          108 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cgatatcttc
      241 tgagatacaa atcggactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcaggg aacacaggga ttttacgcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt gccatcggac acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct cagcgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003697             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10816:5727
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003697
VERSION     KCWK01003697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10816:5727"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69435.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       398..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           87 a          157 c          122 g          105 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcgctct cgggacatct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 cctcgctcag tgtctgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgacatcg gtggttataa ctatgtctcc tggtaccaac agcatccagg cacagccccc
      241 aaagtcatga tttatgaggt cagtaagcgg ccctcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccaggctga ggacgaggct
      361 gattattact gcagctcata tacaggcatc aacagttaca tcttcggtgg tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01003698             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:13350:4167
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003698
VERSION     KCWK01003698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13350:4167"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69436.1"
                     /translation="AYFCQVWDSETDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          150 c          127 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gactctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaagccac cgcaggcccc tatgcaggtc
      241 atctatgctg ataacaaacg gccctcaggg atccctgaga gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctatttc
      361 tgtcaggtgt gggacagtga aactgatcat tacatcttcg gtgctgggac ccggcttacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003699             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:14031:7744
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003699
VERSION     KCWK01003699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14031:7744"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69437.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          162 c          120 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtaataaaaa catgtactgg taccaacaga agccagggag cgctcccagg
      241 ttattcctat actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaactaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtttgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01003700             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:21389:20550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003700
VERSION     KCWK01003700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:21389:20550"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..216
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69438.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       218..251
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           59 a           85 c           74 g           71 t
ORIGIN      
        1 acatgggggg tattataacg ctgtgtcttg gtaccaacag catccaggca aagcccccaa
       61 actcataatt tttgacgtca ttaagcggcc ctcaggggtc tctgatcgct tctctggctc
      121 caagtctggc gacacggcct ccctgaccat ctctgggctc cgggctgagg atgaggctga
      181 ttattactgc agctcatatg caggcagaaa taatttttta ttcggaggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003701             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17135:10245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003701
VERSION     KCWK01003701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17135:10245"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69439.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           88 a          144 c          122 g           95 t
ORIGIN      
        1 acatggggag cattgacggt gcctcagcca tggcctggac ttttctcctc ctcggcctcc
       61 ttgcttactg cacaggctct gcggcctcct atgatctgac tcagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gtgggggaga caacattgga agtcaaagtg
      181 tgcactggta ccagcacaag ccaccgcagg cccctgtact ggtcatcttt tattataccg
      241 aacggccctc aggaatccct gagcgattct ctggctccaa atcagggaac accgccaccc
      301 tgaccatcag cggggtcgag gccggggatg aggctgacta ttactgtcag gtgtgggaca
      361 caactattga tcacggcttc ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003702             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:23077:16838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003702
VERSION     KCWK01003702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:23077:16838"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..425
                     /note="immunoglobulin light chain variable region"
     V_region        105..425
     V_segment       105..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69440.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       390..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>464
                     /gene="IGLC"
BASE COUNT           94 a          144 c          126 g          100 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccatcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccaa gatcacctgc tctggagatg
      181 cactgccaaa aaaatatgct tattggttcc agcagaagcc aggccagtcc cctgtgttga
      241 tcatcgatga ggacaccaaa cggccctctg ggatccctga gagattctct ggctccagct
      301 cagggacagt ggccaccttg actatcagtg gggcccaggt ggaggatgaa gctgactact
      361 actgttactc agcagacagc agtggttatg gcttattcgg aggagggacc cggctgaccg
      421 tcctacgtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003703             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:7165:4088
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003703
VERSION     KCWK01003703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7165:4088"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69441.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          161 c          126 g          109 t
ORIGIN      
        1 acatgggggc tcattcctgg ctgtggctca ggaagcagag cctggagcat ctccaccatg
       61 gcctgggctc cactcctcct caccctcctc gctcactgca cagggtcttg ggctgaggtt
      121 gtgttcactc agccccattc tgtgtcgggg tctccggggc agacggtcac catctcctgc
      181 acccgcagca gtggcagcat tgacaacggc tttgtgtact ggtaccagca gcggccgggc
      241 agcgctccca ccactgtgat ttacaaagat aaccaaagac cctctggggt ccctgatcgg
      301 ttctctggct ccatcgacag ctcctccaac tctgcctccc tcaccatctc tggactgaaa
      361 tctgaggacg aggctgacta ttactgtcag tcttatgaca gcagcagtgt attattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01003704             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:24659:7614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003704
VERSION     KCWK01003704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:24659:7614"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    66..387
                     /note="immunoglobulin light chain variable region"
     V_region        66..387
     V_segment       66..351
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <315..>359
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69442.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       355..387
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        388..>425
                     /gene="IGLC"
BASE COUNT           87 a          134 c          117 g           87 t
ORIGIN      
        1 acatgggcat ggcctggacc cttctcctcc tcggcctcct cgcttactgc acaggctctg
       61 cgacctccta tgaactgact cagtcaccct cagtgtcagc ggcctcagga cagccggcca
      121 ggatcacctg tgggggagac aacattggaa ctaaaactgt gcactggtac cagcagaagc
      181 caccgcaggg ccctgtattg gtcatctttg ctgatagtaa acggccctca gggatccctg
      241 agcgattctc tggctccaac tcagggaaca ccgccaccct gaccatcagc agggtcgagg
      301 ccggggatga ggctgactat tactgtcagg tttgggacag tagtagtaaa tggatattcg
      361 gcggggggac ccggctaacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      421 tcccg
//
LOCUS       KCWK01003705             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:12701:22237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003705
VERSION     KCWK01003705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12701:22237"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69443.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          163 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agccgctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003706             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:7764:9104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003706
VERSION     KCWK01003706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:7764:9104"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69444.1"
                     /translation="DYYCQVWNNIYKYAVF"
     J_segment       396..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          141 c          137 g          102 t
ORIGIN      
        1 acatggggga gcctgacttt gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgctcacttt acaggctctg tggcctccta tgagttgcct
      121 cagccacgct cagtgtccgt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aacattggaa gtaatagtgt gcattggtac cagcagaagc caccgcgggc ccctgtattg
      241 gtcatctctg ttgatagcga acggccctca gggatccctg agcgattctc tggttccaga
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtggaataa tatttataaa tacgcggtat tcggcggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003707             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:26811:9005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003707
VERSION     KCWK01003707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:26811:9005"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69445.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          163 c          120 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgcg
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003708             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:7731:12666
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003708
VERSION     KCWK01003708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7731:12666"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69446.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          157 c          118 g          115 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcaag ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtctt atgatgctgt gtcttggtac caacagcctc caggcaaagc
      241 cccccaactc ataatttttg aggtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgctgct catatgtagg cagcaacact tacatcttcg atgttgggac
      421 ccggctcacc gtcctaggtc agtccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003709             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:29457:14361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003709
VERSION     KCWK01003709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:29457:14361"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69447.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tacacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003710             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:23995:10020
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003710
VERSION     KCWK01003710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:23995:10020"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69448.1"
                     /translation="DYYCCSRSSSSTYVF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           82 a          161 c          118 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac gttggtggtt ataattctgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaagtc atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagt ctgaggacga
      361 ggctgattat tactgttgtt cacgttcaag cagcagcact tacgtcttcg gtcctgggac
      421 ccggctcacc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003711             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:18840:16225
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003711
VERSION     KCWK01003711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18840:16225"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..392
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69449.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       406..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           89 a          153 c          121 g          111 t
ORIGIN      
        1 acatggggct gggatctcag gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccccgact
      121 cagactccct ctgtgtccgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgata ttgggtatta tcatgctgtg tcttggtacc agcatcatcc aggcaaagcc
      241 cccaaactca tgatttatga ggtcaataaa cggcccgcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccagac tgaggatgag
      361 gctgattatt actgtagctc atatgcaggc agcaacagtt tattcttcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003712             305 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:16629:3005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003712
VERSION     KCWK01003712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 305)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16629:3005"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..267
                     /note="immunoglobulin light chain variable region"
     V_region        6..267
     V_segment       6..227
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>239
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69450.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       231..267
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        268..>305
                     /gene="IGLC"
BASE COUNT           65 a           83 c           90 g           67 t
ORIGIN      
        1 acatgggggg agacaatatt ggaagtgaag ttgtcaactg gtaccagcag aagccaccgc
       61 aggcccctgt ggtggtcatc tatgctgatt atgaacggcc ctcagggatc cctgagcgat
      121 tctctggctc caaatcaggg aacacggcca ccctgaccat cagcggagtc gaggccgggg
      181 atgaggctga ctattactgt caggtttggg acatttatat tgatcatccg gtgttattcg
      241 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      301 tcccg
//
LOCUS       KCWK01003713             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:16901:14818
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003713
VERSION     KCWK01003713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16901:14818"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69451.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgtacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003714             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:16264:18561
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003714
VERSION     KCWK01003714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16264:18561"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..237
                     /note="immunoglobulin light chain variable region"
     V_region        8..237
     V_segment       8..197
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <165..>209
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69452.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       204..237
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>275
                     /gene="IGLC"
BASE COUNT           59 a           81 c           74 g           61 t
ORIGIN      
        1 acatggggaa gccagggagt cccccccggt atcttctgag gtacaaatca gactcagata
       61 agggccaggg ctctggagtc cccagccgct tctctggatc caaagatgct tcagcgaaca
      121 cagggatttt acacatctct ggactccagt ctgaggatga ggctgactat tactgtgcca
      181 ttggacacag cagcggtgat tatatcttcg gtggtgggac ccggctcacc gtcctaggtc
      241 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003715             398 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:16924:5202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003715
VERSION     KCWK01003715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 398)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:16924:5202"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..360
                     /note="immunoglobulin light chain variable region"
     V_region        12..360
     V_segment       12..320
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <288..>332
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69453.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       327..360
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        361..>398
                     /gene="IGLC"
BASE COUNT           84 a          125 c          100 g           89 t
ORIGIN      
        1 acatgggctc caagcctatg ctgactcagc cggcctccct ctcagcatct cctggagcat
       61 cagccagtct cacatgcacc ttcagcggtg gcatcaatgt tgctggctac cacatatact
      121 ggtaccagca gaagccaggg agtccccccc ggtatcttct gaggtacaaa tcagactcag
      181 ataagggcca ggggtctgga gtccccagcc gcttctctgg atccaaagat gcttcagcga
      241 acacagggat tttacgcatc tctggactcc agtctgagga tgaggctgac tattactgtg
      301 ccatcggaca cagcagcggt gattatatct tcggtgctgg gacccggctc atcgtcctag
      361 gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01003716             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:12377:10520
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003716
VERSION     KCWK01003716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12377:10520"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69454.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          154 c          127 g          114 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc acgatctcct
      181 gcagtgggag caactccaac attggatatt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctatgaaa ataataagcg accctctggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccactcct atgacagcag tttgagtggt gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003717             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:15652:10977
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003717
VERSION     KCWK01003717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15652:10977"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    75..391
                     /note="immunoglobulin light chain variable region"
     V_region        75..391
     V_segment       75..361
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <324..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69455.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       362..391
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        392..>431
                     /gene="IGLC"
BASE COUNT           83 a          136 c          116 g           96 t
ORIGIN      
        1 actggggtgt ctccaccatg gcctggactc ctctctggct caccctcctc agtctttgca
       61 caggttctat ggtttcttct gagctgactc aggaccctgc agtgtctgtg gccttgggac
      121 agacagtcag gattacctgc caaggagaca gcctcagaag ctcttatgca agctggtacc
      181 aacagaggcc aggccaggcc cctgtgctgg tcgtctatgg taacaactac cggccctcag
      241 ggatcccaga gcgattctct ggctcctact cacgaaacac agcttccttg accatctctg
      301 gggctcaggt ggaagatgag gctgactatt actgtgactc ctgggacagc agcggaaccc
      361 aattcggagg agggacccgg ctgaccgtcc tgggtcagcc caaggctgcc ccctcggtca
      421 ctctcttccc g
//
LOCUS       KCWK01003718             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:21618:5326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003718
VERSION     KCWK01003718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21618:5326"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..224
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69456.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       226..263
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           63 a           87 c           82 g           69 t
ORIGIN      
        1 acatgggggt agtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtt
       61 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      121 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      181 tgaggacgag gccgattatt tctgccaggt gtttgacagt agtgttgtgt tcttcggagg
      241 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01003719             339 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:21871:13446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003719
VERSION     KCWK01003719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 339)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21871:13446"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..301
                     /note="immunoglobulin light chain variable region"
     V_region        8..301
     V_segment       8..262
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <229..>273
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69457.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       264..301
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        302..>339
                     /gene="IGLC"
BASE COUNT           72 a           97 c           88 g           82 t
ORIGIN      
        1 acatggggac tcacctgcac cttgagcagt ggcatcagtg ttggtactta caggatattc
       61 tggtaccagc agaggccagg gagtcctccc cggtatcttc tgaaccacca cacagactca
      121 gataaacatc agggctctgg agtccccagc cgcttctctg gatccaaaga tgcttcggcc
      181 aatgcaggga ttttgctcat ctctgggctc cagtctgagg atgaggctga ctattactgt
      241 atgatttggc acaacaatgc ttatgtgtta ttcggaggag ggacccggct gaccgtccta
      301 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003720             346 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:6633:5594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003720
VERSION     KCWK01003720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 346)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 346)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:6633:5594"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..308
                     /note="immunoglobulin light chain variable region"
     V_region        8..308
     V_segment       8..268
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <233..>280
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69458.1"
                     /translation="DYYCSSYAGSNTHWLF"
     J_segment       278..308
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        309..>346
                     /gene="IGLC"
BASE COUNT           72 a          110 c           85 g           79 t
ORIGIN      
        1 acatgggggg tctcctggac agtcggtcac catctcctgc actggaacca gcagtgacat
       61 cggtggttat aactatgtct cctggtacca gctacaccca ggcaaagccc ccaaactcat
      121 gatttatgat gtcaataagc ggccctcagg ggtctctgat cgcttctctg gctccaaatc
      181 tgacaacacg gcctccctga ccatctctgg gctccaggct gaggatgaga ctgattatta
      241 ctgcagctca tatgcaggca gcaacactca ttggcttttc ggcggaggga cccggctgac
      301 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003721             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:7344:4780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003721
VERSION     KCWK01003721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7344:4780"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69459.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       398..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          154 c          123 g          105 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctaca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagaccc
      241 caaattcatg atttatgagg tcagtcaacg gcccgcaggg gtctctgatc gtatctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tggttattac tgcagctcat ttgcaggtac caacactggc ttaatcggtg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003722             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:10226:7203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003722
VERSION     KCWK01003722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10226:7203"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..417
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69460.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       418..454
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           94 a          158 c          124 g          116 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact tcacagttcc agggtcctgg
      121 gcccagtctg tgctgacgca gccgccctca gtgtctgggg cgcccggaca gagggtcacc
      181 atctcctgca ctgggagcag ctccaacatt ggagattatt ttgtgcagtg gtaccagcac
      241 cttccaggaa cggcccccaa actcctcatc tatgaaaata ataagcgacc ctcagggatt
      301 tctgatcgat tctctggctc ccagtctgga acctcagcct ccctgaccat cactggactc
      361 cagtctgagg atgaggctga ttattactgc cagtcctatg acagcagttt gattgctgtg
      421 ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCWK01003723             326 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:3669:7992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003723
VERSION     KCWK01003723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 326)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:3669:7992"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..288
                     /note="immunoglobulin light chain variable region"
     V_region        6..288
     V_segment       6..250
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <213..>260
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69461.1"
                     /translation="DYYCQVWDTTLDHGLF"
     J_segment       252..288
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        289..>326
                     /gene="IGLC"
BASE COUNT           71 a           99 c           92 g           64 t
ORIGIN      
        1 acatgggaca gacggccagg atcacctgtg ggggagacaa cattggaagt caaagtgtgc
       61 actggtacca gcacaagcca ccgcaggccc ctgttctggt catcttttat tataccgaac
      121 ggccctcagg aatccctgag cgattctctg gctccaaatc agggaacacc gccaccctga
      181 ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta ctgtcaggtg tgggacacaa
      241 ctcttgatca cggcttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      301 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003724             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:10089:5884
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003724
VERSION     KCWK01003724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10089:5884"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69462.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       390..424
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT          106 a          136 c          119 g          101 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct gaccactgtt
       61 ctgctcccct ttctcactct ctgcacaggc tctgaggcct cctatgagct gacacagcca
      121 ccctcagtgt ctgtgtcccc aggacagacg gccaggatca cctgctctgg agaaatactg
      181 gcaaaaaaat atactcagtg gttccaacag cagccaggcc aggccccttt cctggtgata
      241 tataaagaca gtgagaggcc ctcagggatc cctgagcgat tctctagctc cagttcaggg
      301 acaacaatta ccttgaccat cagtggggcc caggcagaag atgaggctga ctattactgt
      361 caatcagtag acagcagtgg aaatcttccg ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003725             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:22817:16251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003725
VERSION     KCWK01003725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:22817:16251"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69463.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          165 c          121 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttga tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tctatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003726             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:25176:18356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003726
VERSION     KCWK01003726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:25176:18356"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..265
                     /note="immunoglobulin light chain variable region"
     V_region        1..265
     V_segment       1..228
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69464.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       231..265
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           61 a           89 c           92 g           61 t
ORIGIN      
        1 acatgggggg gagacaacat tggaactaaa tatgtccact ggtaccagca gaagccagcg
       61 caggcccctg tgttggtcat ctatgctgat agcagacggc cctcagggat ccctgagcga
      121 ttctctggct ccaactcagg gagcaccgcc accctgacca tcagcggggt cgaggccggg
      181 tatgaggctg actatttctg tcaggtgtgg gacgatagta gtgatcatcc ggtattcggc
      241 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      301 ccg
//
LOCUS       KCWK01003727             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:12247:12179
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003727
VERSION     KCWK01003727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12247:12179"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..266
                     /note="immunoglobulin light chain variable region"
     V_region        3..266
     V_segment       3..227
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69465.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       232..266
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           61 a           94 c           75 g           74 t
ORIGIN      
        1 acatgggggt tcttacacca tattctggta ccagcagaag ccagggagtc ctccccggtt
       61 ccttctgtac tactactcag actcaaataa tcaccagggc tctggagtcc ccagccgctt
      121 ctctggatcc aaagatgctt cagccaatgc agggctttta ctgatctctg ggctccagtc
      181 tgaagatgag gctgactatt actgtgccat gtggcacagc agcgcttatg ccttattcgg
      241 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      301 cccg
//
LOCUS       KCWK01003728             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13792:8287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003728
VERSION     KCWK01003728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13792:8287"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69466.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          154 c          120 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003729             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:10734:11333
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003729
VERSION     KCWK01003729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:10734:11333"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69467.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>460
                     /gene="IGLC"
BASE COUNT           95 a          143 c          123 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctacacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaagatc acctgctctg gagatgcact
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 cgatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003730             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:22930:18940
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003730
VERSION     KCWK01003730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22930:18940"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69468.1"
                     /translation="DYYCQVWDTSIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          144 c          130 g           97 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag ggtctgcggc ctccaatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtgag ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct atactggtca
      241 tcttttatta taccgaacgg ccctcaggag tccctgagcg attctctggc tccaaatcag
      301 ggaacatcgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaagt attgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003731             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:5174:17546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003731
VERSION     KCWK01003731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:5174:17546"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69469.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          152 c          122 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacgcgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003732             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:16049:18728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003732
VERSION     KCWK01003732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16049:18728"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69470.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           86 a          159 c          125 g          101 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gaacagtgga
      181 cacaggagct acaccatcgc gtggcatcag cagcagcaag ggaaggcccc tcgattcttg
      241 atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt attgtcagac gtgggatatt ggcatttggg tgttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003733             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:10058:10778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003733
VERSION     KCWK01003733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10058:10778"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69471.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       398..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           93 a          150 c          132 g           97 t
ORIGIN      
        1 acatggggat cctggcttca gaagcagcat ctgggacatg tcagccatgg cctggacgcc
       61 tctcctcctc agcctcctcg ctcactgcac aggctctgtg gcctcctatg agctgactca
      121 gccaccctca gtgtcggtgt ccccaggaca gacagccagc atcacctgct ctggaaataa
      181 attggggaat gtatatgctt actggttcca gcagaagcca ggccaggccc ctgtagtggt
      241 catctacaaa gataccaacc ggccctcagg gatccctgag cgattctctg gctccgactc
      301 agggaacacg gccaccctga ccatcagcag ggtcgaggct ggggatgagg ccgactattt
      361 ttgtgctgca gcctatggca gtggcagcag ctggcagtgg gtattcggcg gagggacccg
      421 gctaatcgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003734             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:8008:4711
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003734
VERSION     KCWK01003734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8008:4711"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..388
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69472.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       389..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           93 a          138 c          127 g          100 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagagctct ggggtgtctc caccatggcc tggactcctc
       61 tctggctcac cctcctcagt ctttgcacag gttctgtggt ttcttctgag ctgactcagg
      121 accctgcagt gtctgtggcc ttgggacaga cagtcaggat cacctgccaa ggagacagcc
      181 tcagaagtta ttatgcaagt tggtaccagc agaagccagg ccaggcccct atactggtcg
      241 tctatggtaa caattaccgg ccctcaggga tcccagagcg attctctggc tccagtacac
      301 gaaacacagc ttccttgacc atcactgggg ctcaggtgga agatgaggct gactattact
      361 gtgactcctg ggacagccgc ggaacccaat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003735             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:21946:3883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003735
VERSION     KCWK01003735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:21946:3883"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69473.1"
                     /translation="DYYCGLGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          158 c          117 g          108 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcacgggt ggcatcaatg
      181 ttgctgacta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacacat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt ggccttgggc acagcagcgg tgattacatc ttcgctgatg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003736             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:18676:8535
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003736
VERSION     KCWK01003736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18676:8535"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..433
                     /note="immunoglobulin light chain variable region"
     V_region        88..433
     V_segment       88..396
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69474.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           92 a          157 c          113 g          109 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttga gcagtggcaa tgttggtagt
      181 tacagcatat tctggtacca gcagaagcca gggagtcctc cccggtacct tctttactac
      241 tactcagact caagtaacca ccaggactct ggagtcccca gccgcttctc tggatcgaaa
      301 gatgtttcag ccaatgcagg gcttttactg atctctgggc tccagtctga agatgaggct
      361 gactattact gtgccacatg gcacagcagc gcttcttaca tcttcggggg ggggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01003737             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:20503:8047
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003737
VERSION     KCWK01003737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20503:8047"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..266
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <233..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69475.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       275..305
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           73 a          109 c           84 g           77 t
ORIGIN      
        1 acatgggggg gcccccggac agagggtcac catctcctgc attagcagca gttccaacat
       61 cggggcggct tattatgtat cctggtacca acagttccca ggaacagccc ccaaactcct
      121 catctttgaa aacaataagc gaccctcagg ggtttctgac cgattctctg gctccaagtc
      181 tggtccctca gcctccctga ccatcactgg actccaatca gaggatgagg ctgattatta
      241 ctgtttagca tgggatacca gcctgaattg gatcttcggc ggagggaccc ggctgaccgt
      301 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003738             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18749:19541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003738
VERSION     KCWK01003738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18749:19541"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69476.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggagtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003739             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:13208:15099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003739
VERSION     KCWK01003739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13208:15099"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69477.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          162 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggtctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003740             380 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:17000:9974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003740
VERSION     KCWK01003740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 380)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17000:9974"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    142..342
                     /note="immunoglobulin light chain variable region"
     V_region        142..342
     V_segment       142..305
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <267..>314
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69478.1"
                     /translation="DYYCQSGDSSGNHWVF"
     J_segment       306..342
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        343..>380
                     /gene="IGLC"
BASE COUNT           79 a          112 c          104 g           85 t
ORIGIN      
        1 acatgggggg ctgtggttct aggaggaaga gctctgggtg tctcaccatg acctggacca
       61 ctgttctgct cccctttctc actctctgca caggctctga ggcctcctat gagctgacac
      121 agccaccctc agtgtcagtg ccccctctgc tggtgatata taaagacagt gagaggccct
      181 cagggatccc tgagagattc tctagctcca gtccagggcc aacatttacc ttgaccaaca
      241 gtggggccca ggcagaagat gaggctgact attactgtca atcaggagac agcagtggta
      301 atcattgggt attcggcgga gggacccggc taagcgtcct aggtcagccc aaggctgccc
      361 cctcggtcac tctcttcccg
//
LOCUS       KCWK01003741             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:8663:14910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003741
VERSION     KCWK01003741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8663:14910"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..445
                     /note="immunoglobulin light chain variable region"
     V_region        109..445
     V_segment       109..402
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69479.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          156 c          122 g          110 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg tcaccatctc ctgcactggg
      181 agcagctcca acatcggggc gggttattat gtatcctggt accagcagtt cccaggaaca
      241 gcccccaaac tcctcatcta tgaaaataat aaacgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggtac ctcagcctcc ctgaccatca ctggactcca atctgaggat
      361 gaggctgatt attactgctc agcatgggat agcagcctga gtatcaatta catcttcggt
      421 tctgggaccc gtctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003742             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:12747:11371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003742
VERSION     KCWK01003742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12747:11371"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69480.1"
                     /translation="DYYCHVYDTRTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           87 a          167 c          118 g          113 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atttactggt accatcagaa gccagggcgc gctcccaggt
      241 ttttcctcta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgcg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tgtatgacac tcgtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003743             319 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:23619:20228
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003743
VERSION     KCWK01003743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 319)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 319)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23619:20228"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..281
                     /note="immunoglobulin light chain variable region"
     V_region        8..281
     V_segment       8..241
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <209..>253
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69481.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       248..281
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        282..>319
                     /gene="IGLC"
BASE COUNT           69 a           91 c           84 g           75 t
ORIGIN      
        1 acatgggggt ggcatcactg ttgctggcta ccatatatat tggtaccagc agaagccagg
       61 gagtcccccc cggtatcttc tgaggtacaa atcagactca gataagggcc agggctctgg
      121 agtccccagc cgcttctctg gatccaaaga tgcttcagcg aacacaggga ttttacgcat
      181 atctggactc cagtctgagg atgaggctga ctattactgt gccattggac acagcagcgg
      241 tgattatatc ttcggtgctg ggacccgtct caccgtccta ggtcagccca aggcttcccc
      301 cacggtcact ctgttcccg
//
LOCUS       KCWK01003744             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11189:7617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003744
VERSION     KCWK01003744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11189:7617"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69482.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          162 c          108 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccaacaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003745             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:5389:6788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003745
VERSION     KCWK01003745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5389:6788"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69483.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          147 c          130 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtacac tggtaccagc acaagccacc gcaggcccct gttctggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttgttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003746             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:10902:3791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003746
VERSION     KCWK01003746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10902:3791"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69484.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       415..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          156 c          123 g          110 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg gttcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agcatctggg gcccccggac agagggtcac catctcctgc
      181 attagcagca gctccaacat cggggcggct tattatgtat cctggtacca acagttacca
      241 ggaacagccc ccaaactcct catctttgaa aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggtccctca gcctccctga ccatcactgg actccaatct
      361 gaggatgagg ctgattatta ctgtttagca tgggatacca gcctgaattg gatcttcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01003747             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:7571:11542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003747
VERSION     KCWK01003747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7571:11542"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69485.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          141 c          133 g          102 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccacgatcac ctgtggggga gacaacattg
      181 gaagtgaagt tgtcaactgg taccagcaga ggccaccgca ggcccctgtg gtggtcatct
      241 atgctgatta tgaacggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acacggccac cctgaccatc agcggagtcg aggccgggga tgaggctgac tattactgtc
      361 aggtttggga catttatatt gatcatccgg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003748             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:12658:15398
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003748
VERSION     KCWK01003748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12658:15398"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..426
                     /note="immunoglobulin light chain variable region"
     V_region        104..426
     V_segment       104..388
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69486.1"
                     /translation="DYHCNSYAGSGVYIF"
     J_segment       391..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>466
                     /gene="IGLC"
BASE COUNT           84 a          154 c          117 g          111 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cgttggatat tataatgctg tgtcttggta ccaacaacat ccaggcaaac cccccaaact
      241 catgatttat gaggtcagta agcggccctc aggggtctct gatcgcttct ctggctccaa
      301 gtctggcaac acggcctccc tatccatctc tgggctccag gctgaggacg aggctgatta
      361 tcattgcaac tcatatgcag gtagtggtgt ttacatcttc ggtgctggga cccgactcac
      421 cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003749             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20501:17862
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003749
VERSION     KCWK01003749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20501:17862"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69487.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           90 a          156 c          126 g          112 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca ccctctcctg
      181 cactgggagc agctccaaca ttggaaatta ttatgtgcag tggtaccagc aggttccagg
      241 aacggccccc aaactcctca tctatgaaaa taataagcga ccctcagggg tttctgatcg
      301 attctctggc tcccagtctg gtacctcagc ctccctgacc atcactggac tccagtctga
      361 cgatgaggct gattattact gtcagtccta tgatagcagc ctgagtgctg tgttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01003750             373 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:22744:18762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003750
VERSION     KCWK01003750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 373)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22744:18762"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..335
                     /note="immunoglobulin light chain variable region"
     V_region        11..335
     V_segment       11..297
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <260..>307
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69488.1"
                     /translation="DYYCQVWDTSIDHGLF"
     J_segment       299..335
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        336..>373
                     /gene="IGLC"
BASE COUNT           82 a          115 c          102 g           74 t
ORIGIN      
        1 acatggggcc tcctatgatc tgactcagcc accctcggtg tcagtgtccc caggacagac
       61 ggccaggatc acctgtgagg gagacaacat tggaagtcaa agtgtgcact ggtaccagca
      121 caagccaccg caggccccta tactggtcat cttttattat accgaacggc cctcaggaat
      181 ccctgagcga ttctctggct ccaaatcagg gaacaccgcc accctgacca tcagcggggt
      241 cgaggccggg gatgaggctg actattactg tcaggtgtgg gacacaagta ttgatcacgg
      301 cttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      361 cactctcttc ccg
//
LOCUS       KCWK01003751             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:14504:4428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003751
VERSION     KCWK01003751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14504:4428"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69489.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       391..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          141 c          137 g           98 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag actctgcggc ctcctatgat ctgactcagc
      121 caccctcgat ttcagtgtcc ccaggacaga cggccagggt cacctgtggg ggagacaaca
      181 tcggaggtga agttgtgaat tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tctatgctga tagcgagcgg ccctcaggga tcccggagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg agatgaggct gactattact
      361 gtcaggtgtg ggaccttaat agtcatcatc tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003752             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:5686:5522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003752
VERSION     KCWK01003752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:5686:5522"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69490.1"
                     /translation="DYYCSSYAGSNNLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          153 c          121 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacaat ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003753             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:19530:15476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003753
VERSION     KCWK01003753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19530:15476"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69491.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtctc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003754             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:25083:14509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003754
VERSION     KCWK01003754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:25083:14509"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..426
                     /note="immunoglobulin light chain variable region"
     V_region        96..426
     V_segment       96..389
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69492.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       390..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          153 c          117 g          103 t
ORIGIN      
        1 acatgggaca gaaggcagga ctcaggacaa tctccagcat ggcctggttc cctctcgtcc
       61 tcaccctcct cactcactgt gcagggtcct gggcccagtc tgtgctgact cagcctccct
      121 cagcgtctga ggccgccagg aacagtgtcg ccatctcctg ttctggaagc aactccaaca
      181 tcggaagtca tagtgtatcc tggtaccagc acctcccagg aacagctccc aaactcctca
      241 tctattatga tgatcaacga gcctcgggtg tctctgaccg attctctggc tccaggtctg
      301 gcacgtcagc ctccctggcc atcagtgggc tccagaccga ggatgaggct gattattact
      361 gcgcagcatg ggatgatagc ctgagaggtt acatcttcgg tgatgggacc cggctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01003755             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:19269:14610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003755
VERSION     KCWK01003755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:19269:14610"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69493.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          161 c          123 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagacttcc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003756             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:16232:9849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003756
VERSION     KCWK01003756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16232:9849"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69494.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>478
                     /gene="IGLC"
BASE COUNT           91 a          160 c          113 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtccgac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttccg
//
LOCUS       KCWK01003757             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:5358:6354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003757
VERSION     KCWK01003757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5358:6354"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69495.1"
                     /translation="DYYCAIGHMSGNYVF"
     J_segment       409..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          155 c          117 g          112 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctgt gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacacacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgaaatataa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tacttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acatgagcgg taattatgtc ttcggttctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003758             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:14766:15952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003758
VERSION     KCWK01003758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14766:15952"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69496.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           95 a          154 c          111 g          117 t
ORIGIN      
        1 atggggactg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcg cagcctgtgc tgactcagcc aacctccctc
      121 tcagcttctc ctggagcatc agccagactc acctgcacct tgaacagtgg catcagtgtt
      181 gctaattaca ggatattctg gtaccaccag aagccaggga gtcctccccg gtatcttctg
      241 aactaccaca cagactcaga tattcaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcggccaa tgcagggatt ttactcatct ctggactcca gtctgaggat
      361 gaggctgact attactgtat gatttggcac aacaatgctt attgggtttt cggcggaggg
      421 acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003759             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:18760:17022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003759
VERSION     KCWK01003759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18760:17022"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    50..395
                     /note="immunoglobulin light chain variable region"
     V_region        50..395
     V_segment       50..358
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <326..>367
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69497.1"
                     /translation="DYYCQVYDSNAVLF"
     J_segment       362..395
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        396..>433
                     /gene="IGLC"
BASE COUNT           85 a          149 c          102 g           97 t
ORIGIN      
        1 acatgggctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtact
       61 gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      121 gagcagtgac ctcagtgttg gcagtaaaaa catgtactgg taccagcaga agccagggag
      181 cgctcccagg ttattcctct actactactc cgactcagac aaccaactgg gacctggggt
      241 ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc
      301 tgggctccag cctgaggacg aggccgatta ttactgccag gtgtatgaca gtaatgctgt
      361 tttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      421 cactctcttc ccg
//
LOCUS       KCWK01003760             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:18057:8965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003760
VERSION     KCWK01003760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18057:8965"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..385
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69498.1"
                     /translation="DYYCSSWESSLNWIF"
     J_segment       387..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           88 a          148 c          122 g          104 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gcatctgggg cccccgggca gagggttacc atctcctgca ctgggagcag ctccaacatc
      181 ggggcgggtt tttatgtgtc ctggtaccaa cagttccctg gaacagcccc caaactcctc
      241 atctatgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggttcctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgctcatcat gggaaagcag cctgaattgg atattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003761             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:5577:6127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003761
VERSION     KCWK01003761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:5577:6127"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69499.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           87 a          166 c          123 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagcca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagccc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003762             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:14854:23165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003762
VERSION     KCWK01003762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14854:23165"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69500.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          151 c          122 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgta
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctctt gttctggaag catctccagc
      181 attggaagta gtgatgtatg ttggtaccag caactcccag gaacggcccc caaactcctc
      241 atcaattata gtgatcagcg actctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcccctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcct gggatagcag cctgagcagt ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003763             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15757:8257
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003763
VERSION     KCWK01003763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15757:8257"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69501.1"
                     /translation="DYYCQTWDTGIDVF"
     J_segment       397..433
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           88 a          159 c          121 g          103 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggg
      181 cacaacagct acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggtacttg
      241 atgtggctta aaagtgatgg tagccacagt aagggggacg ggatccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatact ggcattgatg tgttcggaag cggcaccaag
      421 ttgaccgtcc tcggtcagcc caaggcttcc cccttggtca ctctgttccc g
//
LOCUS       KCWK01003764             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:23871:3798
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003764
VERSION     KCWK01003764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23871:3798"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69502.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           88 a          165 c          124 g          109 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcgtcccc gggagcatcg gccagactcc cctgcaccct gaccagtgac
      181 ctcagcgttg gtagtaaaaa catgtattgg taccagcaga agccagggag cgctcccagg
      241 tcattcctct actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagcc ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctaa tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01003765             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12189:15996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003765
VERSION     KCWK01003765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12189:15996"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69503.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       400..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          158 c          123 g          105 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggttat aactatgtct cctggtacca acaccatcca ggcacagccc
      241 ccaaagtcat gatttatgag gtcagtaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tatacaggca tcaacagtta catcttcggt ggtgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003766             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:21719:18644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003766
VERSION     KCWK01003766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21719:18644"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69504.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          150 c          115 g          109 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcagttgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003767             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:12173:12967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003767
VERSION     KCWK01003767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12173:12967"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69505.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       397..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          145 c          142 g           93 t
ORIGIN      
        1 acatgggggc ctgggcctca ggaggcagca ttgacggtgc ctcagccatg gcctggactt
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggcctcctat gatctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc gggggagaca
      181 agattggaag tgaagttgtg aactggtacc agcagaagcc agcgcaggcc cctgtgctgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac ggccaccctg accatcagcg gggtcgaggc cgggggtgag gctgactatt
      361 actgtcaggt gtgggacatg cgtagtgatc aaccgctatt cggcggaggg acccggctaa
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003768             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:10857:8732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003768
VERSION     KCWK01003768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:10857:8732"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..389
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69506.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       391..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          149 c          122 g          107 t
ORIGIN      
        1 acatggggga caggaggcag cactcaggac agtctccagc atggcctggt ctcctctcct
       61 cctcaccctt ctcattcact gcacagggtc ctgggcccag tctgtgctga cgcagccgcc
      121 ctcagtgtct ggggcgcccg ggcagagggt caccatctcc tgcactggga gcagctccaa
      181 cattggaggt tattatgtgc agtggtacca gcagcttcca ggaacggccc ccaaactcct
      241 catctatgaa aatgataaac gaccctcagg ggtttctgat cgattctctg gctcccagtc
      301 tgattcctca gcctccctga ccatcactgg actccagtct gaggatgagg ctgattatta
      361 ctgccagtcc tatgacagca gcttgagtgt tgtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003769             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:19915:13149
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003769
VERSION     KCWK01003769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19915:13149"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..388
                     /note="immunoglobulin light chain variable region"
     V_region        58..388
     V_segment       58..351
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <319..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69507.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       355..388
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           77 a          143 c          109 g           97 t
ORIGIN      
        1 acatgggggg ctccactcct cctcaccctc ctcgctcact gcacagggtc ttgggctgag
       61 gttgtgttca ctcagcccca ttctgtgtcg gggtctccgg ggcagacggt caccatctcc
      121 tgcacccgca gcagtggcag cattgacaac ggctttgtgt actggtacca gcagcggccg
      181 ggcagcgctc ccaccactgt gatttacaaa gataaccaaa gaccctctgg ggtccctgat
      241 cggttctctg gctccatcga cagctcctcc aactctgcct ccctcaccat ctctggactg
      301 aaatctgagg acgaggctga ctattactgt cagtcttatg acagcagcag tgtattattc
      361 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      421 ttcccg
//
LOCUS       KCWK01003770             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:8191:14446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003770
VERSION     KCWK01003770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8191:14446"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69508.1"
                     /translation="DYYCAFGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          157 c          116 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccaac aaaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcagactca gataggggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctggtctc cagtctgagg
      361 atgaggctga ctattactgt gcctttgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003771             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:10622:14954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003771
VERSION     KCWK01003771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:10622:14954"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69509.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       398..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           86 a          155 c          123 g          105 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcatctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagcattgac aatggctttg tgtactggta ccagcagcgg ccgggcagcg ctcccaccac
      241 tgtgatttac aaagataacc aaagaccctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctgga ctgaaatctg aggacgaggc
      361 tgactattac tgtcagtctt atgacagcag cagtgtatta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003772             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:25499:8670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003772
VERSION     KCWK01003772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:25499:8670"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69510.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           95 a          157 c          126 g          106 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagactccct cagcgtctga ggccgccagg aagagtgtca ccatctcctg
      181 ttctggaagc agctccaaca tcggaagaaa tactgtatcc tggtaccagc agctcccagg
      241 aacagctccc aaactcctca tctattatag tgatcaacga gcctcaggtg tctctgaccg
      301 attctctggc tccaagtctg gcacgtcagc ctccctggcc atcagcgggc tccaggccga
      361 ggatgaggct gattattact gcgcagcatg ggatgatagc ctgagcggtt acatcttcgg
      421 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01003773             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:9479:7670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003773
VERSION     KCWK01003773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9479:7670"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..404
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69511.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       406..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           86 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt agtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt tctgccaggt gtttgacagt agtgttgtgt tcttcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01003774             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:19131:5291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003774
VERSION     KCWK01003774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19131:5291"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69512.1"
                     /translation="DYYCQSTDTSGNYIF"
     J_segment       389..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          105 a          133 c          123 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggaggaat
      181 actggcaaaa aaatatgctc agtggttgca gcagaagcca ggccaggccc ctgtgttggt
      241 aatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gttccagttc
      301 agggacaaca gttgccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca acagacacca gtggtaatta catcttcggt gctgggaccc ggctcaacgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003775             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:9243:11041
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003775
VERSION     KCWK01003775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9243:11041"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69513.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           93 a          161 c          108 g          111 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggaacatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcta
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt cctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003776             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:14162:15067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003776
VERSION     KCWK01003776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14162:15067"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..229
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <197..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69514.1"
                     /translation="DYYCGIGHSSGDYIF"
     J_segment       232..269
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           68 a           92 c           80 g           67 t
ORIGIN      
        1 acatggggtt gctgactacc acatacactg gtaccagcag aagccaggga gtcccccccg
       61 gtatcttctg aggtacaaat cagactcaga taagggccag ggctctggag tccccagccg
      121 cttctctgga tccaaagatg cttcagcgaa cacagggatt ttacgcatct ctggactcca
      181 gtctgaggat gaggctgact attactgtgg cattgggcac agcagcggtg attacatctt
      241 cgctgatggg acccgactca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      301 gttcccg
//
LOCUS       KCWK01003777             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:16235:2566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003777
VERSION     KCWK01003777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:16235:2566"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69515.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       414..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccaacaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggtgt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctaa tgtcttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01003778             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18883:14092
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003778
VERSION     KCWK01003778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18883:14092"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..394
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69516.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       408..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          153 c          122 g          112 t
ORIGIN      
        1 acatggggtg ctgggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccccga
      121 ctcagactcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tattgggtat tatcatgctg tgtcttggta ccagcatcat ccaggcaaag
      241 cccccaaact catgatttat gaggtcaata aacggcccgc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag actgaggatg
      361 aggctgatta ttactgtagc tcatatgcag gcagcaacag tttattcttc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003779             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:21737:4310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003779
VERSION     KCWK01003779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:21737:4310"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69517.1"
                     /translation="DYYCQTWDTGIVSF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          158 c          121 g          103 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gtactctgag cagtggacac
      181 agcagctaca ccatcgcatg gcatcagcac cagcaaggga aggcccctcg gtatttgatg
      241 tggcttaaaa gtgatggcag ccacagcaag ggggacggga tccctgatcg cttctcaggc
      301 tccagttccg gggctgagcg ctacctcacc atctccaatt tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatactggc attgtgtcat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003780             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:8579:15968
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003780
VERSION     KCWK01003780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:8579:15968"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69518.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       398..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          155 c          121 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctaca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagaccc
      241 caaattcatg atttatgagg tcagtcaacg gccctcaggc gtctctgatc gtatctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tggttattac tgcagctcat ttgcaggtac caacactggc ttaatcggtg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003781             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:11269:18628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003781
VERSION     KCWK01003781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11269:18628"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..444
                     /note="immunoglobulin light chain variable region"
     V_region        96..444
     V_segment       96..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69519.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       407..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          165 c          116 g          109 t
ORIGIN      
        1 acatggggcc cactgtgggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctccaagcc tatgctgact cagccggcct
      121 ccctctctgc atctcctgga gcatcagcca gtctcacatg caccttcagc ggtggcatca
      181 ctgttgctgc ctaccacata cactggtacc aacagaagcc agggagtcct ccccggtatc
      241 ttctgaggtt caaatcagac tcagataagg accagggctc tggagtcccc agccgcttct
      301 ctggatccaa agatgcctca gcgaacacag ggattttacg catctctggg ctccagtctg
      361 aggatgaggc tgactactac tgtgccattg ggcacagcag cggtgattac atcttcggtg
      421 ctgggacccg cctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01003782             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:8464:10955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003782
VERSION     KCWK01003782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8464:10955"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69520.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           92 a          159 c          114 g          108 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaat caccaggact ctggagtccc cagccgcttc tccggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggg ggggggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003783             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:23251:14964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003783
VERSION     KCWK01003783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23251:14964"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69521.1"
                     /translation="DYYCALWHSSAIWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          161 c          111 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gagactgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt cctgtcccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagac tcagttgcac cttgaacagc ggcatcaatg
      181 ttggtagtta caccatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 ttcactacta ctcagactca agtaatcacc agggctctgg tgtccccagc cgcttctctg
      301 gatccaaaga tgtttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccctatggc acagcagcgc tatttgggta ttcggcggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003784             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:12174:18272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003784
VERSION     KCWK01003784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12174:18272"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69522.1"
                     /translation="DYYCHVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          164 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atctactggt accagcagaa gccagggagc gctccctgtt
      241 tattcctgtt ctaccagtcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcacg tgtatgacag tagtgcaaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003785             295 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:17492:17678
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003785
VERSION     KCWK01003785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 295)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17492:17678"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..257
                     /note="immunoglobulin light chain variable region"
     V_region        8..257
     V_segment       8..217
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <185..>229
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69523.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       220..257
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>295
                     /gene="IGLC"
BASE COUNT           65 a           93 c           75 g           62 t
ORIGIN      
        1 acatgggcac atacactggt accagcagaa gccagggagt cctccccggt atcttctgag
       61 atacaaatca gactcagata aggaccaggg ctctggagtc cccagccgct tctctggatc
      121 caaagatgcc tcagcgaaca cagggatttt acgcatctct gggctccagt ctgaggatga
      181 ggctgactac tactgtgcca ttgggcacag cagcggtgat tacatcttcg ctgctgggac
      241 ccgcctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003786             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:16496:4303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003786
VERSION     KCWK01003786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16496:4303"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69524.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          155 c          118 g          112 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgactacca cgtacactgg tatcagcaga agccaggggg tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggcctgg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaat acagggattt tacacatctc tggtttccag tctgaggatg
      361 aggctgacta ttactgtgcc attggccacg gcagcggtga ttacatcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003787             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:15237:14782
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003787
VERSION     KCWK01003787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15237:14782"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69525.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       385..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           90 a          143 c          124 g          102 t
ORIGIN      
        1 acatgggggg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactcccca tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagccg gccaggatca cctgctctgg agatgtattg
      181 ccaaaaaaat atgcttattg gttccagcag aagccaggcc agtcccctgt attggtcatc
      241 tctgaggaca ccaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtggagg atgaagctga ctactactgt
      361 tactcagcag acagtagtgg tcatggcttc ttcggaggag ggaccctgct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003788             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:18283:6435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003788
VERSION     KCWK01003788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18283:6435"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69526.1"
                     /translation="DYSCQVWDSESDYYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          146 c          133 g           96 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctttga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaatta aatttgtcca ctggtaccag cagaagccag cgcaggcccc tgtgaaggtc
      241 atctatgctg atgacaaacg gccctcaggg atccctgaga gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattcc
      361 tgtcaggtgt gggacagtga gagtgattat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003789             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20291:10814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003789
VERSION     KCWK01003789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20291:10814"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69527.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       405..439
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           91 a          159 c          114 g          113 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgacccagcc aacctccctc
      121 tcagcatctc cgggagcatc agtcagactc agctgcacct tgagcagtgg catcaatgtt
      181 ggttcttaca ccatattctg gtaccagcag aagccaggga gtcctccccg gttccttctg
      241 tactactact cagactcaaa taatcaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcagccaa tgcagggctt ttactgatct ctgggctcca gtctgaagat
      361 gaggctgact attactgtgc catgtggcac agcagcgctt atgccttatt cggaggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003790             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:17354:5674
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003790
VERSION     KCWK01003790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:17354:5674"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69528.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       399..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           94 a          151 c          116 g          111 t
ORIGIN      
        1 acatggggtc tggagccagg gatcccttcc aatatcagca ccatggcctg gactctgctc
       61 ctcctccagt ttcctcctca cttgctgccc agggtccaat tctcaggctg tagtgactca
      121 ggagccctca atgactgtgt ccccaggagg gacagtcact ctcacctgtg cttccagcac
      181 tggagcagtc accagtggtc actctccaca ctggttccag cagaaacctg gacaagcccc
      241 caagacactg atttataata caaactacag acactcctgg actcctgccc ggttctcagg
      301 ctccctcctt gggggtaaag ctgccctgac actgtcaggt gcgcagcctg aggatgaggc
      361 tgagtattat tgtttactgt actatagtgg tgctcagctg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003791             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:16620:3647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003791
VERSION     KCWK01003791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16620:3647"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69529.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          165 c          124 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc ggcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003792             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15034:19457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003792
VERSION     KCWK01003792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15034:19457"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69530.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       385..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           98 a          141 c          129 g           90 t
ORIGIN      
        1 acatgggggt ctcaggaggc agcattgacg gtgcctcagc catggcctgg acccttctcc
       61 tcctcggcct cctcgcttac tgcacaggct ctgcgacctc ctatgagctg actcaggcac
      121 cctcagtgtc agcggcctca ggacagacgg ccaggatcac ctgtggcgga gacaacattg
      181 gaattaaaaa tgtccactgg taccagcaga agccagcaca ggcccctgtg gtagtcatct
      241 atgctgataa caaacggccc tcagggatcc ctgagcgact ctctggctcc aactcaggga
      301 atattgccac cctgaccatc agcagggtcg aggccgggga tgaggcagac tattactgtc
      361 aggtgtggga cagtagtagt aaatgggtat tcggcggagg gacccggcta accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003793             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:7559:10208
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003793
VERSION     KCWK01003793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7559:10208"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69531.1"
                     /translation="EYYCSAWDSSLTGGFF"
     J_segment       406..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          155 c          123 g          107 t
ORIGIN      
        1 acatggggag cttcagctgt ggctagagaa gacaggactc aggacaatct ccagcatggc
       61 ctgcttccct ctcatcctca ccgtcctcac tcactgtgca ggatcctggg cccagtctgt
      121 gctgactcaa cctccctcag cgtctggggc ccccgggcag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaatta tgtatactgg taccagcagt tctcagggaa
      241 ggcccccaga ctcctcatcc ataataataa tcagcgaccc tcaggggtcc ctgatcgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctgaccatc agtgggctcc agtccgagga
      361 tgaggctgaa tattactgct cagcatggga tagcagtctg accggtggct ttttcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01003794             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:9554:13298
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003794
VERSION     KCWK01003794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9554:13298"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..444
                     /note="immunoglobulin light chain variable region"
     V_region        96..444
     V_segment       96..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69532.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          163 c          123 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcccagcc tgtgctgact cagccaccct
      121 ccctgtctgc gtccccggga gcatcggcca gactcccctg caccctgacc agtgacctca
      181 gcgttggtag taaaaacatg tattggtacc agcagaagcc agggagcgct cccaggtcat
      241 tcctctacta ctactccgac tcagacaagc agctgggacc tggggtcccc aatcgagtct
      301 ctggctccaa ggagacctca agtaacacag cgtttttgct catctctggg ctccagcctg
      361 aggacgaggc cgactattac tgtcaggtgt atgacagtag tgctaatgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003795             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:1957:14850
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003795
VERSION     KCWK01003795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:1957:14850"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69533.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           90 a          155 c          125 g          111 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcacaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagtctg agcggttaca tcttcggcgc
      421 tgggacccgg ctcgccgtcc taggtcagtc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01003796             332 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:10680:9816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003796
VERSION     KCWK01003796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 332)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:10680:9816"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..294
                     /note="immunoglobulin light chain variable region"
     V_region        8..294
     V_segment       8..254
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>266
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69534.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       258..294
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>332
                     /gene="IGLC"
BASE COUNT           73 a           89 c          100 g           70 t
ORIGIN      
        1 acatgggagg aaagacggcc aggatcacct gtgggggaga caatattgga agtgaagttg
       61 tcaactggta ccagcagaag ccaccgcagg cccctgtggt ggtcatctat gctgattatg
      121 aacggccctc agggatccct gagcgattct ctggctccaa atcagggaac acggccaccc
      181 tgaccatcag cggagtcgag gccggggatg aggctgacta ttactgtcag gtttgggaca
      241 tttatattga tcatccggtg ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      301 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003797             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:11483:16996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003797
VERSION     KCWK01003797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11483:16996"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69535.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          156 c          121 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc caccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaataa tgtgtcctgg taccagcacc tcccaggaac
      241 agctcccaaa ctcctcatct attataatga tcaacgaggc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcgtggga tgatagcctg agcagttaca tcttcgctgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01003798             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:12334:14883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003798
VERSION     KCWK01003798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12334:14883"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..437
                     /note="immunoglobulin light chain variable region"
     V_region        91..437
     V_segment       91..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69536.1"
                     /translation="DYYCSIGHSSGLYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>477
                     /gene="IGLC"
BASE COUNT           89 a          158 c          116 g          114 t
ORIGIN      
        1 atggggactg tggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc aagcctatgc tgactcagcc ggcctccctc
      121 tcagcatctc ctggagcatc agccagtctc acatgcacct tcaccggtgg catcaatgtt
      181 gctgtctacc acatacactg gtaccagcag aagccaggga gtcccccccg gtttcttctg
      241 aggtacaaat cagactcaga taagggccag ggctctggag tccccagccg cttctctgga
      301 tccagtaatg cttcagcgaa cacagggatt ttacgcattt ctgggctcca gtctgaggat
      361 gaggctgact attactgttc cattggacac agcagcggtc tttacatctt cggtgctggg
      421 acccggctca ccgtcctggg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01003799             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:14637:17215
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003799
VERSION     KCWK01003799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14637:17215"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..213
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69537.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       215..251
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           61 a           90 c           79 g           59 t
ORIGIN      
        1 acatggggga agtcaaagtg tacactggta ccagcacaag ccaccgcagg cccctgttct
       61 gctcatcttt tattataccg aacggccctc aggaatccct gagcgattct ctggctccaa
      121 atcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      181 ttactgtcag gtgtgggaca caactattga tcacggcttg ttcggaggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003800             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:13565:11993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003800
VERSION     KCWK01003800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13565:11993"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..297
                     /note="immunoglobulin light chain variable region"
     V_region        8..297
     V_segment       8..254
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69538.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       263..297
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>335
                     /gene="IGLC"
BASE COUNT           70 a           99 c          101 g           65 t
ORIGIN      
        1 acatgggggc ctcaggacag acggccagga tcacctgtgg gggagacaac attggaacta
       61 aatatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc atctatgctg
      121 ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactca gggaacaccg
      181 ccaccctgac catcagcggg gtcgaggccg ggtatgaggc tgactatttc tgtcaggtat
      241 gggacgatag tagtgatcat ccggtattcg gcggagggac ccggctgacc gtcctaggtc
      301 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003801             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:14392:8459
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003801
VERSION     KCWK01003801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14392:8459"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..441
                     /note="immunoglobulin light chain variable region"
     V_region        108..441
     V_segment       108..404
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69539.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       407..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           88 a          159 c          129 g          103 t
ORIGIN      
        1 acatggggcc tggctgtggc tcaggaagca gagcctggag cgtctccacc atggcctggg
       61 ctccactcct cctcaccctc ctcgctcact gcacagggtc ttgggctgag gttctgttca
      121 cgcagcccca ttctgtgtcg gggtctccgg ggcagacggt caccatctcc tgtacccgca
      181 gcagaggcaa cattgacaat agttatgtgc agtggtacca gcagcgcccg ggcagtgccc
      241 cgaccacagt gatttacaga gataaccaaa gagcctctgg ggtccctgat cggttctctg
      301 gctccatcga cagctcctcc aactctgcct ccctcaccat ctctgggctg aagtctgagg
      361 acgaggctga ctactactgt cagtctactg atggcaacta caatcggtta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003802             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:23254:19357
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003802
VERSION     KCWK01003802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23254:19357"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69540.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          162 c          124 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcggctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003803             283 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:22004:17954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003803
VERSION     KCWK01003803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 283)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22004:17954"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..245
                     /note="immunoglobulin light chain variable region"
     V_region        9..245
     V_segment       9..206
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>217
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69541.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       208..245
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        246..>283
                     /gene="IGLC"
BASE COUNT           55 a           86 c           78 g           64 t
ORIGIN      
        1 acatgggggg taccagcaga agccagggag cgctcccagg ttattcctgt actactactc
       61 cgactcagac aagcagctgg gacctggggt ccccaatcga gtctctggct ccaaggagac
      121 ctcaagtaac acagcgtttt tgctcatctc tgggctccag cctgaggacg aggccgatta
      181 tttctgccag ctgtttgaca gtagtgttgt gttcttcgga ggagggaccc gactgaccgt
      241 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003804             355 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:5873:10647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003804
VERSION     KCWK01003804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 355)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5873:10647"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..317
                     /note="immunoglobulin light chain variable region"
     V_region        125..317
     V_segment       125..280
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>289
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69542.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       281..317
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        318..>355
                     /gene="IGLC"
BASE COUNT           67 a          113 c           86 g           89 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcacttc acagttccag ggtcctggga
      121 gcagctcctc atctatgaaa ataataagcg accctcaggg atttctgatc gattctctgg
      181 ctcccagtct ggaacctcag cctccctgac catcactgga ctccagtctg aggatgaggc
      241 tgattattac tgccagtcct atgacagcag tttgattgct gtgttattcg gaggagggac
      301 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003805             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:16106:19219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003805
VERSION     KCWK01003805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16106:19219"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..426
                     /note="immunoglobulin light chain variable region"
     V_region        96..426
     V_segment       96..389
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69543.1"
                     /translation="DYYCAVWDNSLTSPLF"
     J_segment       396..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           92 a          153 c          113 g          106 t
ORIGIN      
        1 acatgggaca gaaggcagga ctcaggataa tctccagcat ggcctggttc cctctcgtcc
       61 tcaccctcct cactcactgt gcagggtcct gggcccagtc tgtgctgact cagccaccct
      121 cagcgtctgg gactcccggg cagagtgtca ccatctcttg ctctggaagc aactccaaca
      181 ttggaaataa ttatgtatac tggtaccagc acctcccagg aacggccccc aagctcctca
      241 tctattatag ttatcagcga ccctcagggg tccctgaccg attctctggc tctaagtctg
      301 gcacctcagc ctccctggcc atcactggtc tccgaactga ggatgaggct gattattact
      361 gtgcagtatg ggataacagc ctgaccagtc cgttgttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003806             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:4299:5982
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003806
VERSION     KCWK01003806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:4299:5982"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69544.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          158 c          121 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacgag ccgcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003807             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:19432:17319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003807
VERSION     KCWK01003807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19432:17319"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..441
                     /note="immunoglobulin light chain variable region"
     V_region        108..441
     V_segment       108..404
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69545.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       407..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           87 a          160 c          129 g          103 t
ORIGIN      
        1 acatggggcc tggctgtggc tcaggaagca gagcctggag cgtctccacc atggcctggg
       61 ctccactcct cctcaccctc ctcgctcact gcacagggtc ttgggctgag gttctgttca
      121 cgcagcccca ttctgtgtcg gggtctccgg ggcagacggt caccatctcc tgtacccgca
      181 gcagaggcaa cattgacaat agttatgtgc agtggtacca gcagcgcccg ggcagtgccc
      241 cgaccacagt gatttacaga gataaccaaa gcgcctctgg ggtccctgat cggttctctg
      301 gctccatcga cagctcctcc aactctgcct ccctcaccat ctctgggctg aagtctgagg
      361 acgaggctga ctactactgt cagtctactg atggcaacta caatcggtta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003808             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:18044:13933
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003808
VERSION     KCWK01003808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18044:13933"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69546.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          164 c          122 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtggtaaaaa catgcactgg taccagcaga agccagggcg cgctcccagg
      241 tttttcctgt actacaactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcac gtatatgaca gtagtactaa tgtgttattc
      421 ggaggaggga cccgtctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01003809             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:20161:15204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003809
VERSION     KCWK01003809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20161:15204"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    69..393
                     /note="immunoglobulin light chain variable region"
     V_region        69..393
     V_segment       69..350
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <318..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69547.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       359..393
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>431
                     /gene="IGLC"
BASE COUNT           81 a          140 c          126 g           84 t
ORIGIN      
        1 acatgggagc catggcctgg acccttctcc tcctcggcct cctcgctcac tgcacaggga
       61 ctgcgacctc ctatgagctg gctcagccac cctcggtgtc agcggcctca ggacagacgg
      121 ccaggatcac ctgtggggga gacaacattg gaactaacta tgtgcactgg taccagcaga
      181 agccagcgca ggcccctgta gaggtcatct ttgctgataa caaacggccc tcagggatcc
      241 ctgagcgatt ctctggctcc aactcaggga tcaccgccac cctgaccatc agcggggtcg
      301 aggccgggga tgaggctgac tatttctgtc aggtgtgggg cagtcgtagt gatcatccgg
      361 tattcggcgg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      421 ctctcttccc g
//
LOCUS       KCWK01003810             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:7066:4617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003810
VERSION     KCWK01003810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:7066:4617"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    70..391
                     /note="immunoglobulin light chain variable region"
     V_region        70..391
     V_segment       70..354
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <316..>363
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69548.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       355..391
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        392..>429
                     /gene="IGLC"
BASE COUNT           83 a          143 c          110 g           93 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcagcc tccctcagcg tctggggccg ccaggaacgg tgtcgccatc
      121 tcctgttctg gaagcagctc caacatcgga agtcacagtg tctcctggta ccagcagctc
      181 ccaggaacag ctcccaaact cctcatctat tatgatgatc aacgagcctc gggtgtctct
      241 gaccgattct ctggctccag gtctggcacg tcagcctccc tggccatcag tgggctccag
      301 accgaggatg aggctgatta ttactgcgca gcatgggatg atagcctgag aggttacatc
      361 ttcggtgatg ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact
      421 ctgttcccg
//
LOCUS       KCWK01003811             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:11329:15048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003811
VERSION     KCWK01003811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11329:15048"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69549.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           89 a          154 c          126 g          111 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg agatttttat gtgcagtggt accagcacct tccaggaacg
      241 gcccccagac tcctcatcta tgaaaataat aagcgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctggaac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagtttga ttgctgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003812             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:22858:21681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003812
VERSION     KCWK01003812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22858:21681"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69550.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           90 a          161 c          120 g          109 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggaa ataaaaacat atactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtcataca gcgtttttgc tcatttctgg gctccagcct
      361 gaggacgagg ccgactatta ctgtcaggtg tatgacgata gtgctgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003813             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:14806:5190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003813
VERSION     KCWK01003813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:14806:5190"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69551.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       392..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          156 c          118 g          101 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctcgtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac acagccgccc
      121 tcagtgtctg gggccccagg gcagagggtc accatctcct gcactgggag cagctccaac
      181 attggaggtt attatatatc ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 gtctatgaca ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggttcctcag ccaccctgac catcactggg ctccagactg aggatgaggc tgattattac
      361 tgccagtcct atgacagcag tctgagtgct cgggtattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003814             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:18955:12892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003814
VERSION     KCWK01003814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18955:12892"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69552.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           89 a          158 c          120 g          112 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacgtacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg ggtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tctttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003815             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:24618:7123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003815
VERSION     KCWK01003815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:24618:7123"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69553.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          152 c          120 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgagctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctcct gctctggaag cagctccaat
      181 attggaagta attctgtata ctggtaccag cagttcccag gaacggcccc caaactcctc
      241 atctattata gtaatcagcg accctcaggg gtccctgacc gagtctctgg ctctaagtcg
      301 ggcacctcag cttccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgacag cctgagaagt ccgctattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003816             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:5552:15584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003816
VERSION     KCWK01003816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:5552:15584"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..226
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69554.1"
                     /translation="DYYCQVWGMTRDHPVF"
     J_segment       229..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           62 a           87 c           96 g           56 t
ORIGIN      
        1 acatgggggg ggagaccaca ttggaagtga ggttgtgaac tggtaccaac agaagccacc
       61 gcaggcccct gtggtggtct atcctaatag cgaacggccc tcagggatcc ctgagcgatt
      121 ctctggctcc aaatcaggga acacggccac cctgaccatc agcggggtcg aggccgggga
      181 tgaggctgac tattactgtc aggtgtgggg catgactagg gatcatccgg tattcggcgg
      241 agggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01003817             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:16632:14354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003817
VERSION     KCWK01003817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:16632:14354"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69555.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       388..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          147 c          119 g          103 t
ORIGIN      
        1 acatgggggg gctcagaagc agaactctgg gtcctctcca ccatggcctg gacccctccc
       61 ctgctcatcc tcctcactct ctgcacaggt tccgtggttt cctctgagct gactcaggag
      121 cctgcattgt ctgtggcctt gggacaaaca gtcaggatga cctgccaagg agacagcctc
      181 aaaacctatt atgcaagctg gtaccagcag aagccaggcc aggtccctgt gctggtcatc
      241 tatggtaaca actaccggcc ctcagggatc ccaggccgat tctctgtctc ctggtcagga
      301 aacacaggtt ccttgaccat cactgcggct caggtggaag atgaggctga ctattactgt
      361 aagtcctggg acagcagtgg tacccattac atcttcggtg ctgggacccg gctcaccgtc
      421 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01003818             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12430:2777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003818
VERSION     KCWK01003818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12430:2777"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69556.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           91 a          156 c          125 g          115 t
ORIGIN      
        1 acatggggtg cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctcct ctcctcctca cccttctcat tcacttcaca gttccagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcgccatctc
      181 ctgcactggg agcagctcca acattggaga ttattttgtg cagtggtacc agcaccttcc
      241 aggaacggcc cccaaactcc tcatctatga aaataataag cgaccctcag ggatttctga
      301 tcgattctct ggctcccagt ctggaacctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agtttgattg ctgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01003819             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:16472:12229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003819
VERSION     KCWK01003819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16472:12229"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..403
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69557.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       405..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           87 a          152 c          123 g          114 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggttcag gctgccccga
      121 ctcagcctcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tattgggtat tataacgctg tgtcttggta ccaacagcat ccaggcaaag
      241 cccccaaact cataattttt gacgtcatta agcggccctc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcgac acggcctccc tgaccatctc tgggctccgg gctgaggatg
      361 aggctgatta ttactgcagc tcatatgcag gcagaaataa ttttttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003820             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:21952:7925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003820
VERSION     KCWK01003820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21952:7925"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69558.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          163 c          111 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgttgccta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagttacaa atcagactca gataagggcc agggctccgg agtccccagc cgcttctctg
      301 gatccaaaaa tgcttccaca aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003821             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:13909:10208
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003821
VERSION     KCWK01003821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13909:10208"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69559.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          143 c          140 g           92 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccagcg caggcccctg tgctggtcat
      241 ctatgctgat agcgaacggc cctcagggat ccctgagcaa ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg ggtgaggctg actattactg
      361 tcaggtgtgg gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003822             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:5023:12386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003822
VERSION     KCWK01003822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5023:12386"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..398
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69560.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           89 a          156 c          118 g          108 t
ORIGIN      
        1 acatgggggg atctcacgag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 actccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgatattg ggtattatca tgctgtgtct tggtaccaac atcatccagg caaagccccc
      241 aaactcatga tttatgaggt caataaacgg cccgcagggg tctctgatcg cttctctggc
      301 tccaagtccg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 gattattact gcagctcata tgcaggcagc aacactttat tcttcggggg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003823             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22169:18781
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003823
VERSION     KCWK01003823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22169:18781"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69561.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          157 c          120 g          109 t
ORIGIN      
        1 atgggggcag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcacc tccaacatcg gaagcaataa tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctctttt attataatga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctcttgctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgataacctg agcggctaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01003824             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:20239:14867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003824
VERSION     KCWK01003824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20239:14867"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..434
                     /note="immunoglobulin light chain variable region"
     V_region        98..434
     V_segment       98..391
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69562.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           94 a          153 c          119 g          106 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctctcct
       61 tctcactctg ctggttcact gcacagggtc ctgggcccag tctgtgctga cgcagccgcc
      121 ctcagcatct ggggcccccg ggcagagggt caccatctcc tgcactggga gcagctccaa
      181 catcggggcg ggttattatg tatcctggta ccagcagttc ccaggaacag cccccaaact
      241 cctcatctat gaaaataata aacgaccctc aggggtttct gaccgattct ctggctccaa
      301 gtctggtacc tcagcctccc tgaccatcac tggactccaa tctgaggatg aggctgatta
      361 ttactgctca gcatgggata gcagcctgag tatcaattac atcttcggtt ctgggacccg
      421 tctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01003825             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:19793:8370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003825
VERSION     KCWK01003825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19793:8370"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69563.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          147 c          128 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tatactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agtccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003826             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:7826:8146
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003826
VERSION     KCWK01003826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7826:8146"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69564.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       404..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           87 a          162 c          123 g          106 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caacaacatc cagacacagc
      241 ccccaaactc gtgatttatg aggtcaatca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctgacaaca cggcctccct gaccatctct ggcctccagc ctgaggacga
      361 ggctgattat tactgcagct catatgcagg cagcgacact ttcgtgttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003827             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16224:9794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003827
VERSION     KCWK01003827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16224:9794"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..430
                     /note="immunoglobulin light chain variable region"
     V_region        85..430
     V_segment       85..391
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69565.1"
                     /translation="DYYCQMYDNSDVLF"
     J_segment       396..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          157 c          113 g          104 t
ORIGIN      
        1 acatggggag aggtagccgt gtccaccatg gccctgactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctcccagcct gtactgactc agccaccctc cctgtctgca
      121 tccccgggag catcggccag actcccctgc accctgagca gtgacctcag tgttggaagt
      181 aaaaacatgt actggtacca gcagaagcca gggagcgctc ccaggttatt cctgtactac
      241 tactccgact cagacaagca actgggacct ggggtcccca atcgagtctc tggctccaag
      301 gagacctcaa gtaacacagc gtttttgctc atctctgggc tccagcctga ggacgaggcc
      361 gattattact gtcagatgta tgacaatagt gatgtcttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003828             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:11087:17724
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003828
VERSION     KCWK01003828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:11087:17724"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69566.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          147 c          132 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctccgatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa gagtgtgcac tggtaccagc acaagccacc gcaggcccct atcctggtca
      241 tctattatta taccgaacgg ccctcggcga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacactact attgatcatg gctttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003829             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:15749:19810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003829
VERSION     KCWK01003829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15749:19810"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..274
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69567.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       277..314
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           77 a          110 c           89 g           76 t
ORIGIN      
        1 acatggggga gcatcagcca gtctcacatg caccttcagc ggtggcatca atgttgctgc
       61 ctaccacata cactggtacc agcagaagcc agggagtcct ccccggtatc ttctgagata
      121 caaatcagac tcagataagg accagggctc tggagtcccc agccgcttct ctggatccaa
      181 agatgcctca gcgaacacag ggattttacg catctctggg ctccagtctg aggatgaggc
      241 tgactactac tgtgccattg ggcacagcag cggtgattac attttcgctg ctgggacccg
      301 cctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01003830             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:8807:13720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003830
VERSION     KCWK01003830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:8807:13720"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..417
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69568.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       418..454
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           93 a          157 c          133 g          109 t
ORIGIN      
        1 acatgggggg gtgaagcgca gcttcagctg tgggtacaga aggcaggact caggacaatc
       61 tccagcatgg cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg
      121 gcccagtctg tgctgactca gcctccctca gcgtctgagg ccgccaggaa cagtgtcgcc
      181 atctcctgtt ctggaagcag ctccaacatc ggaagtcata gtgtatcctg gtaccagcag
      241 ctcccaggaa cagctcccaa actcctcatc tattatgatg atcaacgggc ctcgggtgtc
      301 tctgaccgat tctctggctc caggtctggc acgtcagcct ccctggccat cagtgggctc
      361 cagaccgagg atgaggctga ttattactgc gcagcatggg atgatagcct gagaggttac
      421 atcttcggtg atgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCWK01003831             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:17356:14219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003831
VERSION     KCWK01003831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17356:14219"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69569.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          154 c          113 g          116 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttggtaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gattttcacc agggctctgg agtccccagc cgcttctctg
      301 ggtccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggta ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003832             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:22246:6202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003832
VERSION     KCWK01003832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:22246:6202"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69570.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          156 c          121 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaacc cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003833             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:26644:9830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003833
VERSION     KCWK01003833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:26644:9830"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69571.1"
                     /translation="DYYCAAWDDTLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          152 c          119 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag caggtccaat
      181 atcggaagta atagtgtatc ctggtaccag cagctcccag gaacagctcc caagctcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagcggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatac cctgagcggt tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003834             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:8185:2238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003834
VERSION     KCWK01003834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8185:2238"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..431
                     /note="immunoglobulin light chain variable region"
     V_region        110..431
     V_segment       110..395
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69572.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       399..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           93 a          146 c          134 g           96 t
ORIGIN      
        1 acatgggggc cctgtctggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggcc tcctcgctta ctgcacaggc tctgcgacct cctatgaact
      121 gactcagtca ccctcagtgt cagcggcctc aggacagccg gccaggatca cctgtggggg
      181 agacaacatt ggaattaaaa ctgtacactg gtaccagcag aagccaccgc agggccctgt
      241 attggtcatc tttgctgata gtaagcggcc ctcagggatc cctgagcgat tctctggctc
      301 caactcaggg aacaccgcca ccctgaccat cagcagggtc gaggccgggg atgaggctga
      361 ctattactgt caggtgtggg acagtagtag taaatggata ttcggcgggg ggacccggct
      421 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003835             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:3398:13589
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003835
VERSION     KCWK01003835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:3398:13589"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69573.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          150 c          134 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gactctgcga cctcctatga cctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta aatatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
      241 atctatgctg ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg ggtatgaggc tgactatttc
      361 tgtcaggtgt gggacgatag tagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003836             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:13338:20995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003836
VERSION     KCWK01003836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13338:20995"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69574.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       392..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>464
                     /gene="IGLC"
BASE COUNT           90 a          144 c          135 g           95 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag actctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtgaac tggtaccagc agaagccacc gcaggcccct gtcctggtca
      241 tctatgctaa taacgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg gggcgttact agtgatcatc ccttattcgg aggagggacc cggctgaccg
      421 tccaaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003837             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:6783:11010
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003837
VERSION     KCWK01003837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:6783:11010"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69575.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          147 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcgac ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003838             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:23070:23455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003838
VERSION     KCWK01003838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:23070:23455"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69576.1"
                     /translation="DYYCQVWDISSDHVLF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           85 a          139 c          142 g           98 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctccgcggc ctcctttgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga acttgtgaac tggtaccaac agaggccacc gcaggcccct gtgctggtca
      241 tgtatgctga tgacgaacgg ccctcaggga tccctgggcg attctctggc tccaaatcag
      301 ggagtacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacattagt agtgatcatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003839             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:19020:5615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003839
VERSION     KCWK01003839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:19020:5615"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..242
                     /note="immunoglobulin light chain variable region"
     V_region        10..242
     V_segment       10..204
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <167..>214
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69577.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       206..242
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        243..>280
                     /gene="IGLC"
BASE COUNT           58 a           88 c           77 g           57 t
ORIGIN      
        1 acatgggagt gtgcactggt accagcacaa gccaccgcag gcccctgtac tggtcatctt
       61 ttattatacc gaacggccct caggaatccc tgagcgattc tctggctcca aatcagggaa
      121 caccgccacc ctgaccatca gcggggtcga ggccggggat gaggctgact attactgtca
      181 ggtgtgggac acaactattg atcacggctt attcggagga gggacccggc tgaccgtcct
      241 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003840             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:17898:17570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003840
VERSION     KCWK01003840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:17898:17570"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..434
                     /note="immunoglobulin light chain variable region"
     V_region        110..434
     V_segment       110..385
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69578.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          150 c          134 g           98 t
ORIGIN      
        1 acatgggggc cctgtctggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggct tcctcgctca ctgcacaggc tctgcgacct cctttgagct
      121 gactcagcca ccctcggtgt cagcggcctc aggacagacg gccaggatca cctgtggggg
      181 agacaacatt ggaattaaat ttgtccactg gtaccagcag aagccagcgc aggcccctgt
      241 gaaggtcatc tatgctgatg acaaacggcc ctcagggatc cctgagagat tctctggctc
      301 caattcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga
      361 ctattcctgt caggtgtggg acagtgagac tgatcattac atcttcggtg ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01003841             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:14233:3984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003841
VERSION     KCWK01003841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14233:3984"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..433
                     /note="immunoglobulin light chain variable region"
     V_region        104..433
     V_segment       104..397
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69579.1"
                     /translation="DYYCATTYGSGSNWQYIF"
     J_segment       398..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>472
                     /gene="IGLC"
BASE COUNT           94 a          151 c          126 g          101 t
ORIGIN      
        1 acatggggat cctggcttca gaagcagcat ctgggacatg tcagccatgg cctggacgcc
       61 tctcctcctc agcctcctcg ctcactgcac aggctctgtg tcctcctatg agctgactca
      121 gtcaccctca gtgtcggtgt ccccaggaca gacagccagc atctcctgct ctggagataa
      181 attcgggact ggatctactt actggtacca gcagaagcca ggccaggtcc ctgttctggt
      241 catctataaa agtgacaacc gcccctcagg gatccctgag cgattctctg gctccaagtc
      301 ggggaggacg tccaacctga ccatcagcgg ggtcgaggct ggggatgagg ccgactatta
      361 ctgtgctaca acctatggca gtgggagcaa ctggcagtac atcttcggtg ctgggacccg
      421 gctcaccgtc ctaagtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01003842             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:18073:22645
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003842
VERSION     KCWK01003842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18073:22645"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69580.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          164 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagcca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003843             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:13410:5851
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003843
VERSION     KCWK01003843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13410:5851"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..440
                     /note="immunoglobulin light chain variable region"
     V_region        114..440
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69581.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>482
                     /gene="IGLC"
BASE COUNT           88 a          155 c          128 g          111 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtctcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc tcagtctggc acgtcagcct ccctggccat cagtgggctc caggccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagtct gagcggttac atcttcggtg
      421 ctgggacccg gctcgccgtc gtaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01003844             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17191:21610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003844
VERSION     KCWK01003844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17191:21610"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..394
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69582.1"
                     /translation="DYYCQSFDSSTVLF"
     J_segment       400..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           81 a          157 c          127 g          107 t
ORIGIN      
        1 acatgggggc tgtggctcag gaagcagagc ctggagcatc tccaccatgg cctgggctcc
       61 gctcctcctc accctcctcg ctcactgcac agggtcttgg gctgaggttg tgttcactca
      121 gccccaatct gtgtcggggt ctccggggca gacggtcacc atctcctgca cccgcagcag
      181 tggcagcatt ggcaacagct atgtgtactg gttccagcag cggccgggca gcgtccccac
      241 tattgtgatt tacaaagatg accaaagacc ctctggggtc cctgatcggt tctctggctc
      301 catcgacagc tcctccaact ctgcctccct caccatctct ggactgaagt ctggggacga
      361 ggctgactat tactgtcagt cttttgacag cagcactgtc ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003845             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:14718:13086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003845
VERSION     KCWK01003845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:14718:13086"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69583.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       393..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>465
                     /gene="IGLC"
BASE COUNT           91 a          145 c          133 g           96 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gactctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtcctggtc
      241 atctatgcta ataacgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcaacggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt ggggcgttac tagtgatcat cccttattcg gaggagggac ccggctgacc
      421 gtccaaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003846             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:26727:6103
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003846
VERSION     KCWK01003846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:26727:6103"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..248
                     /note="immunoglobulin light chain variable region"
     V_region        8..248
     V_segment       8..208
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>220
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69584.1"
                     /translation="VYYCQVWDSSSEWVF"
     J_segment       212..248
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        249..>286
                     /gene="IGLC"
BASE COUNT           59 a           84 c           86 g           57 t
ORIGIN      
        1 acatggggga actaaaactg tgcactggta ccaacagaag gcagcacagg cccctatgct
       61 ggtcatcttt gctgatagca aacggccctc agggatccct gaccgattct ctggctccaa
      121 ctcagggaac accggcaccc tgaccatcag cggggtcgag gccggggatg aggctgtcta
      181 ttactgtcag gtgtgggaca gtagtagtga gtgggttttc ggcggaggga cccggctaac
      241 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003847             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:3650:8713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003847
VERSION     KCWK01003847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:3650:8713"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..386
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69585.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       387..418
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>456
                     /gene="IGLC"
BASE COUNT           93 a          139 c          125 g           99 t
ORIGIN      
        1 acatgggggg gctcagaagc agagctctgg ggtgtctcca ccatggcctg gactcctctc
       61 tggctcaccc tcctcagtct ttgcacaggt tctgtggttt cttctgagct gactcaggac
      121 cctgcagtgt ctgtggcctt gggacagaca gtcaggatca cctgccaagg agacagcctc
      181 agaagttatt atgcaagttg gtaccagcag aagccaggcc aggcccctat actgatcgtc
      241 tatggtaaca attaccggcc ctcagggatc ccagagcgat tctctggctc cagtacacga
      301 aacacagctt ccttgaccat ccctggggct caggtggaag atgaggctga ctattactgt
      361 gactcctggg acagccgcgg aacccaattc ggaggaggga cccggctgac cgtcctaggt
      421 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003848             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:8274:19878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003848
VERSION     KCWK01003848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8274:19878"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..237
                     /note="immunoglobulin light chain variable region"
     V_region        8..237
     V_segment       8..197
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <165..>209
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69586.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       200..237
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>275
                     /gene="IGLC"
BASE COUNT           57 a           86 c           72 g           60 t
ORIGIN      
        1 acatggggaa gccagggagt cctccccggt atcttctgag atacaaatca gactcagata
       61 tggaccaggg ctctggagtc cccagccgct tctctggatc caaagatgcc tcagcgaaca
      121 cagggatttt acgcatctct gggctccagt ctgaggatga ggctgactac tactgtgcca
      181 ttgggcacag cagcggtgat tacatcttcg ctgctgggac ccgcctcacc gtcctaggtc
      241 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003849             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:16258:17845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003849
VERSION     KCWK01003849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16258:17845"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69587.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          146 c          129 g           98 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctttga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaatta aatttgtcca ctggtaccag cagaagccag cgcaggcccc tgtgaaggtc
      241 atctatgctg atgacaaacg gccctcagga atccctgaga gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac tatcagcggg gtcgaggccg gggatgaggc tgactattcc
      361 tgtcaggtgt gggacagtga gactgattat tacatcttcg gttctgggac ccgactcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003850             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:4843:11277
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003850
VERSION     KCWK01003850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:4843:11277"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..388
                     /note="immunoglobulin light chain variable region"
     V_region        58..388
     V_segment       58..349
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <313..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69588.1"
                     /translation="DYYCGAWDSSLSGYIF"
     J_segment       351..388
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           79 a          141 c          109 g           97 t
ORIGIN      
        1 acatgggggt cccctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
       61 tctgtcctga cgcagccgcc ctcagtgtct gcggccccag ggcagaaggt caccatctcc
      121 tgctctggaa gtagctccaa catcgggaga aaatctgtct cctggtacca gcaggtccca
      181 ggaacggccc ccaaactcct caggtatgac aatgataagc gaccctcagg ggtttctgac
      241 cgattctctg gctccaagtc tggttcctca gcctccctgg ccatcactgg actccagact
      301 ggagatgagg ctgattatta ttgcggagca tgggatagca gtctgagtgg ttacattttc
      361 ggtgctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      421 ttcccg
//
LOCUS       KCWK01003851             450 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:25491:5978
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003851
VERSION     KCWK01003851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:25491:5978"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..412
                     /note="immunoglobulin light chain variable region"
     V_region        88..412
     V_segment       88..375
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69589.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       376..412
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>450
                     /gene="IGLC"
BASE COUNT           90 a          144 c          114 g          102 t
ORIGIN      
        1 acatggggag aactctgggt cctctccacc atggcctgga cccctcccct gctcatcctc
       61 ctcactctct gcacaggttc cgtggtttcc tctgagctga ctcaggagcc tgcattgtct
      121 gtggccttgg gacaaacagt caggatgacc tgccaaggag acagcctcaa aacctattat
      181 gcaagctggt accagcagaa gccaggccag gtccctgtgc tggtcatcta tggtaacaac
      241 taccggccct cagggatccc aggccgattc tctgtctcct ggtcaggaaa cacaggttcc
      301 ttgaccatca ctgcggctca ggtggaagat gaggctgact attactgtaa gtcctgggac
      361 agcagtggta cccattacat cttcggtgct gggacccggc tcaccgtcct aggtcagccc
      421 aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003852             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:5925:14751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003852
VERSION     KCWK01003852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5925:14751"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69590.1"
                     /translation="DYYCAAWDESLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          158 c          125 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca ggtcccagga
      241 acacctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgaaagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003853             403 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:7476:12087
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003853
VERSION     KCWK01003853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 403)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7476:12087"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    41..365
                     /note="immunoglobulin light chain variable region"
     V_region        41..365
     V_segment       41..328
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <290..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69591.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       329..365
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>403
                     /gene="IGLC"
BASE COUNT           81 a          127 c          112 g           83 t
ORIGIN      
        1 acatgggggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
       61 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      121 tggaagtaag agtgtgcact ggtaccaaca caagccaccg caggccccta tcctggtcat
      181 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      241 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      301 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      361 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003854             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:12085:7683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003854
VERSION     KCWK01003854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12085:7683"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..343
                     /note="immunoglobulin light chain variable region"
     V_region        13..343
     V_segment       13..304
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69592.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       313..343
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>381
                     /gene="IGLC"
BASE COUNT           77 a          123 c           95 g           86 t
ORIGIN      
        1 acatgggggg cccagtctgt gctgacgcag ccgccctcag catctggggc ccccggacag
       61 agggtcacca tttcctgcat tagcagcagc tccaacatcg gggcggctta ttatgtatcc
      121 tggtaccaac agttcccagg aacagccccc aaactcctca tctttgaaaa taataagcga
      181 ccctcagggg tttctgaccg attctctggc tccaagtctg gtccctcagc ctccctgacc
      241 atcactggac tccaatctga ggatgaggct gattattact gtttagcatg ggataccagc
      301 ctgaattgga tcttcggcgg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      361 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003855             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:18205:15164
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003855
VERSION     KCWK01003855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18205:15164"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69593.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          158 c          123 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaccgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003856             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:14047:13794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003856
VERSION     KCWK01003856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14047:13794"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..431
                     /note="immunoglobulin light chain variable region"
     V_region        107..431
     V_segment       107..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69594.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       397..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           86 a          149 c          139 g           95 t
ORIGIN      
        1 acatggggct gtctgggtct caggaggcag cattgacggt gcctcagcca tggcctggac
       61 ccttctcctc ctcggcctcc tcgctcactg cacaggctct gcgacctcct atgagctggc
      121 tcagccaccc tcggtgtcag cggcctcagg acagacggcc aggatcacct gtgggggaga
      181 caacattgga agtaactatg tgcactggta ccagcagaag ccagcgcagg cccctgtaga
      241 gattatcttt gctgataaca aacggccctc agggatccct gagcgattct ctggctccaa
      301 ctcagggatc accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      361 tttctgtcag gtgtggggca gtcgtagtga tcatccggta ttcggcggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003857             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:17541:16031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003857
VERSION     KCWK01003857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17541:16031"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69595.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          151 c          116 g          107 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cccgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003858             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:17499:4335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003858
VERSION     KCWK01003858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:17499:4335"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    143..250
                     /note="immunoglobulin light chain variable region"
     V_region        143..250
     V_segment       143..211
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <175..>222
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69596.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       216..250
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        251..>288
                     /gene="IGLC"
BASE COUNT           54 a           89 c           78 g           67 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtctgtgt ccccatcagt ggggcccagg cagaagatga ggctgactat
      181 tactgtcaat cagtagacag cagtggaaat cttccgttat tcggaggagg gacccggctg
      241 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003859             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:10542:12335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003859
VERSION     KCWK01003859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10542:12335"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69597.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       414..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           92 a          159 c          126 g          107 t
ORIGIN      
        1 acatggggct cagcttcagc tgcgggtaca gaaggcagga ctcaggataa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgagctgact cagccaccct cagcgtctgg ggctcccggg cagagtgtca ccatctcctg
      181 ctctggaagc agctccaata ttggaagtaa ttctgtatac tggtaccagc agttcccagg
      241 aacggccccc aaactcctca tctattatag taatcagcga ccctcagggg tccctgaccg
      301 agtctctggc tctaagtcgg gcacctcagc ctccctggcc atcactggtc tccgatctga
      361 ggatgaggct gattattact gtgcagcatg ggatgacagc ctgagaagtc cgctattcgg
      421 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01003860             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:9821:11276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003860
VERSION     KCWK01003860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9821:11276"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69598.1"
                     /translation="DYYCCSYRNGNTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          156 c          124 g          110 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gtattggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcaacact cagagacagc
      241 ccccacactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tactgttgtt catataggaa tggaaacact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003861             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:23097:9481
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003861
VERSION     KCWK01003861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23097:9481"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..446
                     /note="immunoglobulin light chain variable region"
     V_region        101..446
     V_segment       101..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69599.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       409..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           86 a          163 c          123 g          112 t
ORIGIN      
        1 acatggggct gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagcagtga
      181 cctcagtgtt ggtagtaaaa acatgtactg gtaccagcag aagccaggga gcgctcccag
      241 gttattcctg tactactact ccgactcaga caagcagctg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt atttctgcca ggtgtttgac agtagtgttg tgttcttcgg
      421 aggagggacc cgactgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01003862             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:12706:20383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003862
VERSION     KCWK01003862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12706:20383"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..398
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69600.1"
                     /translation="DYYCSAWDSSLTGGFF"
     J_segment       400..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           96 a          152 c          122 g          105 t
ORIGIN      
        1 acatggggag ctgtggctag agaagacagg actcaggaca atctccagca tggcctgctt
       61 ccctctcatc ctcaccgtcc tcactcactg tgcaggatcc tgggcccagt ctgtgctgac
      121 tcaaccaccc tcagcgtctg gggcccccgg gcagagtgtc accatctcct gttctggaag
      181 cagctccaac atcggaagta attatgtata ctggtaccag cagttctcag ggaaggcccc
      241 caaactcctc atccataata ataatcagcg accctcaggg gtccctgatc gattctctgg
      301 ctccaagtct ggcacgtcag cctccctgga catcagtggg ctccagtccg aggatgaggc
      361 tgattattac tgctcagcat gggatagcag tctgaccggt ggctttttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003863             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:23084:8580
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003863
VERSION     KCWK01003863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23084:8580"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69601.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          149 c          116 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01003864             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:4698:5941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003864
VERSION     KCWK01003864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:4698:5941"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69602.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          163 c          120 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactacca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003865             450 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:19650:15359
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003865
VERSION     KCWK01003865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19650:15359"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..412
                     /note="immunoglobulin light chain variable region"
     V_region        82..412
     V_segment       82..373
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69603.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       375..412
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>450
                     /gene="IGLC"
BASE COUNT           84 a          144 c          118 g          104 t
ORIGIN      
        1 acatggggac tcaggacagt ctccagcatg gcctggtctc tccttctcac tctgctggtt
       61 cactgcacag ggtcctgggc ccagtctgtg ctgacgcagc cgccctcagc atctggggcc
      121 cccgggcaga gggtcaccat ctcctgcact gggagcagct ccaacatcgg ggcgggtttt
      181 tatgtatcct ggtaccagca gttcccagga aaagccccca agctcctcat ctttgaaaat
      241 aacaagcgac cctcaggggt ttctgaccga ttctctggct ccaagtctgg ttcctcagcc
      301 tccctgacca tcactggact ccaatctgag gatgaggctg attattattg ttcatcatgg
      361 gaaagcagcc tgaattgggt attcggcgga gggacccggc tgaccgtcct aggtcagccc
      421 aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003866             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:22789:14223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003866
VERSION     KCWK01003866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22789:14223"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69604.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          101 a          137 c          123 g          102 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctggggcc tcctatgagg tgacacagtc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagcaatact
      181 ggcaaataat tatgctcagt ggttccagca gaagccagac caggcccctg tgttggtgat
      241 acataaagac actgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacaatt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagtt gacagcagtg cccatcatcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003867             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:18664:12736
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003867
VERSION     KCWK01003867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18664:12736"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..403
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69605.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           86 a          160 c          124 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggta gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattattt ctgccaggtg tttgacagta gtgttgtgtt cttcggagga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003868             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:19876:13272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003868
VERSION     KCWK01003868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19876:13272"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69606.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          153 c          115 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactt tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta ataatgtgtc ctggtaccag cacctcccag gaacagctcc caaactcctc
      241 atctattata atgatcaacg aggctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcgt gggatgatag cctgagcagt tacatcttcg ctgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003869             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:18802:10510
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003869
VERSION     KCWK01003869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18802:10510"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69607.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          143 c          133 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca gggtctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003870             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:20030:6419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003870
VERSION     KCWK01003870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20030:6419"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69608.1"
                     /translation="DYYCQSYDRSLNAVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          152 c          127 g          112 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct catccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac catctcctgc
      181 actgggagca gctccaacat tggagattat tatgtgcagt ggtaccagca gcttccagga
      241 acggccccca tactcctcat ctatgaaaat aataagcgac cctcaggggc ttctaatcga
      301 ctctctggct cccagtctgg tacctcagcc tcgctgacca taagtggact ccagtctgag
      361 gatgaggctg actattactg ccagtcttat gacagaagct tgaatgctgt tttattcggg
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01003871             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:23576:10188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003871
VERSION     KCWK01003871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23576:10188"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..404
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69609.1"
                     /translation="DYYCAAWDDSLRSYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          156 c          126 g          106 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctactataat gatcaacgag gctcaggtgg ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgaggagtta catcttcgct
      421 gctgggaccc gggtcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003872             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:24143:4038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003872
VERSION     KCWK01003872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24143:4038"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69610.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       412..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           90 a          158 c          129 g          107 t
ORIGIN      
        1 acatggggcg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcctcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aagagtgtca ccatctcctg
      181 ttctggaagc agctccaaca tcggaagtaa tagtgtttcc tggtaccagc agctcccaga
      241 aacggctccc aaactcctca tcttttataa tgatcggcga gcctcaggtg tctctgaccg
      301 attctctggc tccaagtctg gcacgtcagc ctccctggcc atcagtgggc tccagaccga
      361 ggatgaggct gattattact gcgcagcatg ggatgatagc ctgagcggtc cggtattcgg
      421 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01003873             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:10327:15027
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003873
VERSION     KCWK01003873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10327:15027"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..254
                     /note="immunoglobulin light chain variable region"
     V_region        8..254
     V_segment       8..214
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69611.1"
                     /translation="DYYCQVWDISTDHPVLF"
     J_segment       218..254
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           61 a           84 c           85 g           62 t
ORIGIN      
        1 acatggggga tatgaagttg tcaactggta ccagcagaag ccaccgcagg cccctgtggt
       61 ggtcatctat gctgattatg aacggccctc agggatccct aaccgattct ctggctccaa
      121 atcagggaac acggccaccc tgaccatcag cggagtcgag gccggggatg aggctgacta
      181 ttattgtcag gtgtgggaca ttagtactga ccatccggtg ttattcggag gagggacccg
      241 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003874             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:16926:11189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003874
VERSION     KCWK01003874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16926:11189"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..442
                     /note="immunoglobulin light chain variable region"
     V_region        109..442
     V_segment       109..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69612.1"
                     /translation="DYYCLEWHDSLSTGLF"
     J_segment       406..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           95 a          152 c          125 g          108 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tccacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcaacatc tggggccccc gggcagaggg tcaccatctc ctgcactggg
      181 aacagcccca atatcggggc gaattattat gtatcgtggt accagcattt cccaggaaca
      241 gcccccaaac tcctcatcta tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggtac ctcagcctcc ctgaccatca ctgggctcca gtctgaggat
      361 gaggctgatt attactgctt agaatggcat gatagcctga gtactggctt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003875             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:19688:9965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003875
VERSION     KCWK01003875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19688:9965"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69613.1"
                     /translation="DYYCCSYRTGNSWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          155 c          126 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccaa cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg tctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattat tgttgctcat ataggactgg aaacagttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003876             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:10213:11696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003876
VERSION     KCWK01003876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10213:11696"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69614.1"
                     /translation="DYYCQTWDTGIVSF"
     J_segment       397..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           87 a          159 c          121 g          104 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgtactct gagcagtgga
      181 cacagcatct acaccatcgc atggcatcag caccagcaag ggaaggcccc tcggtatttg
      241 atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctga tcgcttctca
      301 ggctccagtt ccggggctga gcgctacctc accatctcca atttccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatact ggcattgtgt cattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003877             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:8262:11489
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003877
VERSION     KCWK01003877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8262:11489"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69615.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           90 a          159 c          122 g          109 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggaac atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctggct accccataca ctggtaccag cagaagccag ggagtcctcc ccggtatctt
      241 ctgagataca aatcggactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccagtg atgcttcagc gaacgcaggg actttacgca tctctgggct ccagtctgag
      361 gatgaggctg actattactg tgccattggg cacagcagcg gtgattacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01003878             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:18738:8612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003878
VERSION     KCWK01003878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18738:8612"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..455
                     /note="immunoglobulin light chain variable region"
     V_region        110..455
     V_segment       110..416
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69616.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       418..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           89 a          167 c          124 g          113 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      181 gagcagtgac ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag
      241 cgctcccagg ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt
      301 ccccaatcga gtctctggtt ccaaggagac ctcaagtaac acagcgtttt tgctcatctc
      361 tgggctccag cctgaggacg aggccgatta tttctgccag gtgtttgaca gtagtgttgt
      421 gttcttcgga ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01003879             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:14899:19274
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003879
VERSION     KCWK01003879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14899:19274"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..377
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69617.1"
                     /translation="AYFCQVWDSETDHYIF"
     J_segment       389..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          150 c          126 g           95 t
ORIGIN      
        1 acatgggctg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag actctgcgac ctcctatgag ctgactcagc
      121 caccctcggt gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa ttttgtgcac tggtaccagc agaagccacc gcaggcccct atgcaggtca
      241 tctatgctga taacaaacgg ccctcaggga tccctgagag attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcggag tcgaggccgg ggatgaggct gcctatttct
      361 gtcaggtgtg ggacagtgaa actgatcatt acatcttcgg tgctgggacc cggcttaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01003880             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:16939:18129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003880
VERSION     KCWK01003880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16939:18129"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69618.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          152 c          119 g          101 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagactccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagaa atagtgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagcggg ctccaggccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagcggt tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003881             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:20775:5960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003881
VERSION     KCWK01003881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20775:5960"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69619.1"
                     /translation="DYYCAAWDESLNGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          157 c          126 g          104 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctgggagca gctccaacat cggaagaaat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc gccctggcca tcagcgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgaaagcc tgaacggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003882             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:8029:6781
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003882
VERSION     KCWK01003882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8029:6781"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69620.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           92 a          159 c          114 g          108 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggg ggggggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01003883             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:20950:17829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003883
VERSION     KCWK01003883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20950:17829"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69621.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          158 c          125 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccaaga agggtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003884             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11886:7464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003884
VERSION     KCWK01003884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11886:7464"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69622.1"
                     /translation="DYYCAAWDNTLSGVFF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           92 a          150 c          125 g          114 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcttggg cccagtctgt
      121 gttgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaatag tgtctcctgg taccagcagc tcccaggaac
      241 agctcccaga ctcctcattt attttaatga tcaacgtacc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga taataccttg agcggtgtgt ttttcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01003885             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:7702:10052
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003885
VERSION     KCWK01003885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:7702:10052"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..431
                     /note="immunoglobulin light chain variable region"
     V_region        104..431
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69623.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       395..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          139 c          136 g          104 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaaa gacggccagg atcacctgtg ggggagacaa
      181 tattggaagt gaagttgtca actggtacca gcagaagcca ccgcaggccc ctgtggtggt
      241 catctatgct gattatgaac ggccctcagg gatccctgag cgattctctg gctccaaatc
      301 agggaacacg gccaccctga ccatcagcgg agtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtt tgggacattt atattgatca tccggtgtta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003886             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:25594:13744
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003886
VERSION     KCWK01003886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:25594:13744"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69624.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       404..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           84 a          158 c          128 g          108 t
ORIGIN      
        1 acatgggggc tggggtctcg ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggcggtt ataactatgt ctcctggtac cgacaacatc cagacacagc
      241 ccccaaactc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgctgct cacatgcagg cagtgatatt ttcgtgttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003887             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:12480:7741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003887
VERSION     KCWK01003887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12480:7741"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69625.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          151 c          117 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgagcagt ggcatcagtg
      181 ttggtaagta caggatattc tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagagtca gatgtgcacc aggactctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttattcat ttctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaacgc ttattgggta ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003888             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:20044:7919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003888
VERSION     KCWK01003888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20044:7919"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69626.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           85 a          150 c          136 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 cctccctcgg tgtcagcggc ctcaggacag acggccagga tcccctgtgg gggagacaac
      181 attggaacta aatatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
      241 atctatgctg ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg ggtatgaggc tgactatttc
      361 tgtcaggtgt gggacgatag tagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003889             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:8938:16134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003889
VERSION     KCWK01003889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:8938:16134"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69627.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           94 a          144 c          135 g           87 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgagc tgactcagcc
      121 accctcagtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaatat
      181 tggaactaag aatgtgcact ggtaccagca gaagccagcg caggcccctg tggcggtcat
      241 ctatgctgat accaaacggc cctcagggat ccctgagcga ttctcaggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatgggt attcggcgga gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003890             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:12585:11643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003890
VERSION     KCWK01003890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12585:11643"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..404
                     /note="immunoglobulin light chain variable region"
     V_region        83..404
     V_segment       83..370
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <332..>379
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69628.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       373..404
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        405..>445
                     /gene="IGLC"
BASE COUNT           87 a          139 c          125 g           94 t
ORIGIN      
        1 acatgggatt gacggtgcct cagccatggc ctggactttt ctcctcctcg gcctccttgc
       61 ttactgcaca gactctgcgg cctcctatga tctgactcag ccaccctcgg tgtcagtgtc
      121 cccaggacag acggccagga tcacctgtgg gggagacaac attggaagtg aagttgtgaa
      181 ctggtaccag cagaagccac cgcaggcccc tgtcctggtc atctatgcta ataacgaacg
      241 gccctcaggg atccctgagc gattctctgg ctccaaatca gggaacacgg ccaccctgac
      301 catcagcggg gtcgaggccg gggatgaggc tgactattac tgtcaggtgt ggggcgttac
      361 tagtgatcat cccttattcg gaggagggac ccggctgacc gtccaaggtc agcccaaggc
      421 tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003891             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:12627:20275
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003891
VERSION     KCWK01003891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12627:20275"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..400
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69629.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       409..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           92 a          154 c          122 g          109 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc ggacagaggg tcaccatttc ctgcattagc
      181 agcagctcca acatcggggc ggcttattat gtatcctggt accaacagtt cccaggaaca
      241 gcccccaaac tcctcatctt tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggtcc ctcagcctcc ctgaccatca ctggactcca atctgaggat
      361 gaggctgatt attactgttt agcatgggat accagcctga attggatctt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003892             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:16251:9106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003892
VERSION     KCWK01003892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16251:9106"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69630.1"
                     /translation="DYYCAVWSSSAYIF"
     J_segment       403..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           83 a          158 c          118 g          117 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctgt cacagcctgt gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagtcagac tcacctgcac cttgcgcact ggcctcaatg
      181 ttggtggcta ctacatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgaattacta ctcagactca aatcagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgtttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccgtttggt ccagcagcgc ttacatcttc ggtggtggga
      421 ctcggctcac cgtcctaggt cagcccaagg cctcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003893             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:24717:9425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003893
VERSION     KCWK01003893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:24717:9425"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..448
                     /note="immunoglobulin light chain variable region"
     V_region        115..448
     V_segment       115..411
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69631.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       414..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          161 c          130 g          106 t
ORIGIN      
        1 acatgggggc tcattcctgg ctgtggctca ggaagcagag cctggagcgt ctccaccatg
       61 gcctgggctc cactcctcct caccctcctc gctcactgca cagggtcttg ggctgaggtt
      121 ctgttcacgc agccccattc tgtgtcgggg tctccggggc agacggtcac catctcctgt
      181 acccgcagca gaggcaacat tgacaatagt tatgtgcagt ggtaccagca gcgcccgggc
      241 agtgccccga ccacagtgat ttacagagat aaccaaagag cctctggggt ccctgatcgg
      301 ttctctggct ccatcgacag ctcctccaac tctgcctccc tcaccatctc tgggctgaag
      361 tctgaggacg aggctgacta ctactgtcag tctactgatg gcaactacaa tcggttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01003894             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:24698:23411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003894
VERSION     KCWK01003894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24698:23411"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69632.1"
                     /translation="DYHCQVWDINSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          144 c          136 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gtctctgcgg cctcctatga tctcacgcag
      121 ccaccctcga tttcagtgtc cccaggacag acggccaggc tgacctgtgg gggagacaac
      181 attggcagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atctatgctg acagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgag catcagcggg gtcgaggccg gggatgaggc tgactatcac
      361 tgtcaggtgt gggacattaa tagtcatcat ctgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003895             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:5067:7447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003895
VERSION     KCWK01003895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5067:7447"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..429
                     /note="immunoglobulin light chain variable region"
     V_region        97..429
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69633.1"
                     /translation="DYYCATWDDSLSGYYIF"
     J_segment       393..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>468
                     /gene="IGLC"
BASE COUNT           94 a          152 c          114 g          108 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta atagtgtatc ctggtaccag caactcccag gaacgcctcc caaactcctc
      241 atctatttta atgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgctacat gggatgatag tctgagcggt tattacatct tcggtgctgg gacccggctc
      421 accgtcctaa gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01003896             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:8986:9814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003896
VERSION     KCWK01003896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8986:9814"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..296
                     /note="immunoglobulin light chain variable region"
     V_region        8..296
     V_segment       8..257
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69634.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       259..296
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>334
                     /gene="IGLC"
BASE COUNT           66 a          100 c           88 g           80 t
ORIGIN      
        1 acatgggggg cagagggtca ccatctcctg cactgggacc agctccaaca tcggggcggg
       61 tttttgtgtt tcctggtacc agcagttccc aggaacagcc cccaaactcc tcatgtttga
      121 aaataataag cgaccctcag gggtttctga ccgattctct ggctccaagt ctggttcctc
      181 agcctccctg accatcactg gactccaatc tgaggatgag gctgattatt attgttcatc
      241 atgggaaagc agcctgaatt gggtgttcgg cggagggacc cggctgaccg tcctaggtca
      301 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003897             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14391:23735
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003897
VERSION     KCWK01003897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14391:23735"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69635.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          161 c          113 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaacga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003898             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:17431:9030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003898
VERSION     KCWK01003898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17431:9030"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69636.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          162 c          124 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggcgccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003899             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10464:16830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003899
VERSION     KCWK01003899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10464:16830"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69637.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           82 a          162 c          122 g          102 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtggccac
      181 tacagctaca ccatcgcatg gcatcagcag cagcaaggga aggcccctcg gttcttgatg
      241 tggcttaaga gtgatggcag ccacaccaag ggggacgggg tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatattggc atttgggtat tcggcggagg gacccggcta
      421 atcgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003900             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:10570:14383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003900
VERSION     KCWK01003900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10570:14383"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69638.1"
                     /translation="DYYCQVWGMTSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          143 c          138 g           95 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccactga tctgactcag
      121 ccaccctcgg tgtcagagtc cccaggacag acggccagga tcacctgtgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atctctgcta atagcgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac cattagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaagtgt ggggcatgac tagtgatcat ccggtattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003901             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:10991:5726
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003901
VERSION     KCWK01003901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10991:5726"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69639.1"
                     /translation="DYYCQVWDSSTKYVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          140 c          135 g           98 t
ORIGIN      
        1 acatggggct gactttggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactttacag gctctgcggc ctcctatgaa ctgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa aagtgtgcag tggtaccagc agacgccacc gcaggcccct atactggtca
      241 tttatggtga tagggaacgg ccctcaggga tccctgatcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggatagtagt actaaatatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003902             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:23210:6024
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003902
VERSION     KCWK01003902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:23210:6024"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..434
                     /note="immunoglobulin light chain variable region"
     V_region        110..434
     V_segment       110..391
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69640.1"
                     /translation="DYYCQVWDSSSDHWIF"
     J_segment       397..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           92 a          151 c          137 g           92 t
ORIGIN      
        1 acatgggggc cctgtctggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggcc tcctcgctca ctgcacagac tctgcgacct cctatgagct
      121 gactcagcca ccctcggtgt cagcggcctc aggacagacg gccaggatca cctgtggggg
      181 agacaacatt ggaagtaaat atgtgcactg gtaccagcag aggccaccgc aggcccctgt
      241 gcaagtcatc tatactgata gcagacggcc ctcagggatc cctgagcgat tctctggctc
      301 caactcaggg aacaccgcca ccctgaccat cagcgcggtc gaggccgggg atgaggctga
      361 ctattactgt caggtgtggg acagtagtag tgatcattgg atattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003903             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:6795:13650
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003903
VERSION     KCWK01003903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6795:13650"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..336
                     /note="immunoglobulin light chain variable region"
     V_region        8..336
     V_segment       8..296
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69641.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       303..336
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           79 a          114 c           94 g           87 t
ORIGIN      
        1 acatgggggc ctccctctca gcatctcctg gagcatcagc cagtctcaca tgcaccttca
       61 gcggtggcat cactgttgct ggctaccata tatattggta ccagcagaag ccagggagtc
      121 ccccccggta tcttctgagg tacaaatcag actcagataa gggccagggc tctggagtcc
      181 ccagccgctt ctctggatcc aaagatgctt cagcgaacac agggatttta cgcatatctg
      241 gactccagtc tgaggatgag gctgactatt actgtgccat tggacacagc agcggtgatt
      301 atatcttcgg tgctgggacc cgtctcaccg tcctaggtca gcccaaggct tcccccacgg
      361 tcactctgtt cccg
//
LOCUS       KCWK01003904             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:16039:7440
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003904
VERSION     KCWK01003904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16039:7440"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69642.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       388..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           98 a          142 c          130 g           91 t
ORIGIN      
        1 acatggggct ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgag ctgactcagg
      121 caccctcagt gtcagcggcc tcaggacaga cggccaggat cacctgtggc ggagacaaca
      181 ttggaattaa aaatgtccac tggtaccagc agaagccagc acaggcccct gtggtagtca
      241 tctatgctga taacaaacgg ccctcaggga tccctgagcg actctctggc tccaactcag
      301 ggaatattgc caccctgacc atcagcaggg tcgaggccgg ggatgaggca gactattact
      361 gtcaggtgtg ggacagtagt agtaaatggg tattcggcgg agggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01003905             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:12981:11793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003905
VERSION     KCWK01003905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12981:11793"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69643.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          156 c          127 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgagtc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagtc tgagcggata catcttcggt
      421 actgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003906             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:26558:12716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003906
VERSION     KCWK01003906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:26558:12716"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..339
                     /note="immunoglobulin light chain variable region"
     V_region        13..339
     V_segment       13..299
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69644.1"
                     /translation="DYYCSSYAGSNNFLF"
     J_segment       310..339
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        340..>351
                     /gene="IGLC"
BASE COUNT           72 a          108 c           86 g           85 t
ORIGIN      
        1 acatgggggg ctcaggctgc cccgactcag cctccctctg tgtccgggtc tcctggacag
       61 tcggtcacca tctcctgcac tggaaccagc actaatattg gatattataa tgctgtgtct
      121 tggtaccaac accatccagg caaagccccc agactcatga tttatgacgt cagtaagcgg
      181 ccctcagggg tctctgatcg cttctctggc tccaagtctg gcaacacggc ctccctgacc
      241 atctctgggc tccagactga ggatgaggct gattattact gcagctcata tgcaggcagc
      301 aacaattttt tattcggagg agggacccgg ctgaccgtca ctctcttccc g
//
LOCUS       KCWK01003907             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:8104:10174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003907
VERSION     KCWK01003907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8104:10174"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..436
                     /note="immunoglobulin light chain variable region"
     V_region        103..436
     V_segment       103..399
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69645.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       402..436
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           88 a          156 c          128 g          102 t
ORIGIN      
        1 acatgggggt gtggctcagg aagcagagcc tggagcgtct ccaccatggc ctgggctcca
       61 ctcctcctca ccctcctcgc tcactgcaca gggtcttggg ctgaggttct gttcacgcag
      121 ccccattctg tgtcggggtc tccggggcag acggtcacca tctcctgtac ccgcagcaga
      181 ggcaacattg acaatagtta tgtgcagtgg taccagcagc gcccgggcag tgccccgacc
      241 acagtgattt acagagataa ccaaagagcc tctggggtcc ctgatcggtt ctctggctcc
      301 atcgacagct cctccaactc tgcctccctc accatctctg ggctgaagtc tgaggacgag
      361 gctgactact actgtcagtc tactgatggc aactacaatc ggttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003908             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:20673:19800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003908
VERSION     KCWK01003908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20673:19800"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69646.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           91 a          153 c          120 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctactgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgactattac tgcagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003909             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:20067:21842
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003909
VERSION     KCWK01003909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20067:21842"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69647.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          105 a          137 c          123 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgggg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003910             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:19740:11154
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003910
VERSION     KCWK01003910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:19740:11154"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69648.1"
                     /translation="DYYCQSADSSGNHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          133 c          124 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctcttcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc agtggttcca gcagaagcca ggccaggccc ctgtgttggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgaa cgattctcta gttccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggta gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagca gtggtaatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003911             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:7143:6494
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003911
VERSION     KCWK01003911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:7143:6494"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69649.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          162 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggt acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003912             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:18510:10008
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003912
VERSION     KCWK01003912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18510:10008"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69650.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          159 c          118 g          110 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcac ctccaacatc ggaagcaata atgtatcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcttt tattataatg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctcttgctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcatcatggg atgataccct gagcggctac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01003913             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:18277:14465
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003913
VERSION     KCWK01003913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18277:14465"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69651.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          153 c          122 g          102 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta atagtgtttc ctggtaccag cagctcccag aaacggctcc caaactcctc
      241 atcttttata atgatcggcg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagcggt ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003914             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:15046:12425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003914
VERSION     KCWK01003914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15046:12425"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69652.1"
                     /translation="DYYYYSADSSGNWVF"
     J_segment       372..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           93 a          134 c          114 g          105 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tagcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct tcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattacca aaaaaatatg
      181 cttcttggtt ccagctgaag ccaggccagt cccctgtgat ggtcatcttt gaggacagca
      241 aacggccctc tgggatccct gagagattct ttggctccag tttagggaca gtggccacct
      301 tgactataat tggggcccag gtggaggatg aagatgacta ctactattac tcagcagaca
      361 gtagtggtaa ttgggtattc gccggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003915             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:16657:7922
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003915
VERSION     KCWK01003915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16657:7922"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69653.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           92 a          143 c          133 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca gactctgcga cctcctatga attgactcag
      121 tcgccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacgac
      181 attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tctattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaagcgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003916             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:12027:4969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003916
VERSION     KCWK01003916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12027:4969"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69654.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          143 c          135 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccagggtc acctgtgggg gagacaacat
      181 cggaggtgaa gttgtgaatt ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat accgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccgga gatgaggctg actactactg
      361 tcaggtgtgg gaccttaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003917             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:10315:8560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003917
VERSION     KCWK01003917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:10315:8560"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69655.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       391..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           98 a          144 c          123 g           99 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccatcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagaag
      181 aattgccaaa aaaatatgct tattggttcc agcagaagcc aggccagtcc cctgtccaga
      241 tcatctatga ggacagtaaa cggccctctg ggatccctga gagaatctct ggctccagct
      301 cagggacagt ggccaccttg actatcactg gggcccaggt ggaggatgaa gctgactact
      361 actgtttctc aacagacacc agtggtaatc gggtattcgg cggagggacc cgtctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003918             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:12476:11445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003918
VERSION     KCWK01003918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12476:11445"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69656.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          156 c          121 g          110 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catacactgg taccagcaga agtctgggag tcctccccgg tatcttctaa
      241 gatacaaatc agactcggat cagggccagg gctctggggt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acggggattt tacacgtctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtga ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003919             364 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:12872:19961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003919
VERSION     KCWK01003919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 364)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12872:19961"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..326
                     /note="immunoglobulin light chain variable region"
     V_region        8..326
     V_segment       8..288
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <251..>298
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69657.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       290..326
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        327..>364
                     /gene="IGLC"
BASE COUNT           79 a          111 c          102 g           72 t
ORIGIN      
        1 acatggggat ctgactcagt caccctcggt gtcagtgtcc ccaggacaga cggccaggat
       61 cacctgtggg ggagacaaca ttggaagtca aagtgtgcac tggtaccagc acaagccacc
      121 gcaggcccct gtactggtca tcttttatta taccgaacgg ccctcaggaa tccctgagcg
      181 attctctggc tccaaatcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      241 ggatgaggct gactattact gtcaggtgtg ggacacaact attgatcacg gcttattcgg
      301 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      361 cccg
//
LOCUS       KCWK01003920             500 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12580:7326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003920
VERSION     KCWK01003920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 500)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12580:7326"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    144..460
                     /note="immunoglobulin light chain variable region"
     V_region        144..460
     V_segment       144..430
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <393..>434
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69658.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       431..460
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        461..>500
                     /gene="IGLC"
BASE COUNT           98 a          152 c          138 g          112 t
ORIGIN      
        1 acatggggtc ccttcctatg ataagagagg actggaggtt ccccttagct gtgggctcag
       61 aagcagagct ctggggtgtc tccaccatgg cctggactcc tctctggctc accctcctca
      121 gtctttgcac aggttctatg gtttcttctg agctgactca ggaccctgca gtgtctgtgg
      181 ccttgggaca gacagtcagg attacctgcc aaggagacag cctcagaagc tcttatgcaa
      241 gctggtacca acagaggcca ggccaggccc ctgtgctggt cgtctatggt aacaactacc
      301 ggccctcagg gatcccagag cgattctctg gctcctactc acgaaacaca gcttccttga
      361 ccatctctgg ggctcaggtg gaagatgagg ctgactatta ctgtgactcc tgggacagca
      421 gcggaaccca attcggagga gggacccggc tgaccgtcct gggtcagccc aaggctgccc
      481 cctcggtcac tctcttcccg
//
LOCUS       KCWK01003921             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:9848:18755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003921
VERSION     KCWK01003921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9848:18755"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    65..389
                     /note="immunoglobulin light chain variable region"
     V_region        65..389
     V_segment       65..351
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <314..>361
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69659.1"
                     /translation="DYYCQVWDTTLDHGLF"
     J_segment       353..389
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        390..>427
                     /gene="IGLC"
BASE COUNT           86 a          133 c          120 g           88 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctat gatctgactc agccaccctc ggtgtcagtg tccccaggac agacggccag
      121 gatcacctgt gggggagaca acattggaag tcaaagtgtg cactggtacc agcacaagcc
      181 accgcaggcc cctgttctgg tcatctttta ttataccgaa cggccctcag gaatccctga
      241 gcgattctct ggctccaaat cagggaacac cgccaccctg accatcagcg gggtcgaggc
      301 cggggatgag gctgactatt actgtcaggt gtgggacaca actcttgatc acggcttatt
      361 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      421 cttcccg
//
LOCUS       KCWK01003922             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18101:13099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003922
VERSION     KCWK01003922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18101:13099"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..402
                     /note="immunoglobulin light chain variable region"
     V_region        84..402
     V_segment       84..367
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69660.1"
                     /translation="DYYCQVWDSDSKWVF"
     J_segment       369..402
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        403..>443
                     /gene="IGLC"
BASE COUNT           88 a          142 c          127 g           86 t
ORIGIN      
        1 acatggggat tgacggtgcc tcagccatgg cctggaccct tctcctcctc ggcctcctcg
       61 cttactgcac aggctctgcg acctcctatg agctgactca gccaccctca gtgtcagcgg
      121 cctcaggaca gacggccagg atcacctgtg gcggggacag ccttggaaca aaatatgtgc
      181 actggtacca gcagaagcca acgcaggccc ctgtggtggt catctatgct gataataaac
      241 ggccctcagg gatccctgag cgattctctg gctccaactc agggaacacc gccaccctga
      301 ccatcagcag ggtcgaggcc ggggatgagg ctgactatta ctgtcaggtg tgggacagtg
      361 atagtaagtg ggtcttcggc ggagggaccc ggctaaccgt cccaggtcag cccaaggctg
      421 ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003923             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:15008:12253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003923
VERSION     KCWK01003923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:15008:12253"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..387
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69661.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       401..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           91 a          153 c          117 g          108 t
ORIGIN      
        1 acatggggat ctcaggaggc agcgctctca ggacttctcc accatggtct gggctctgct
       61 cctcctcacc ctcctcactc agggcacagg atcctgggct caggctgccc cgactcagac
      121 tccctctgtg tccgggtctc ctggacagtc ggtcaccatc tactgcactg gaaccagcag
      181 tgatattggg tattatcatg ctgtgtcttg gtaccaacat catccaggca aagcccccaa
      241 actcatgatt tatgaggtca ataaacggcc cgcaggggtc tctgatcgct tctctggctc
      301 caagtctggc aacacggcct ccctgaccat ctctgggctc cagactgagg atgaggctga
      361 ctattactgc agctcatatg caggcagcaa cagtttattc ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003924             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:10034:8477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003924
VERSION     KCWK01003924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10034:8477"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..261
                     /note="immunoglobulin light chain variable region"
     V_region        1..261
     V_segment       1..228
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69662.1"
                     /translation="DYFCQVWDSGSDHYIF"
     J_segment       229..261
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        262..>303
                     /gene="IGLC"
BASE COUNT           62 a           90 c           87 g           64 t
ORIGIN      
        1 acatgggggg gagacaacat tggaactaca tatgtgcact ggtaccagca gaagccacca
       61 caggcccctg tgcaggtcat ctttgctgat agcaaacggc cctcaggggt ccctgaccga
      121 ttctctggct ccaactcagg gaacaccgcc accctgacca tcagcggggt cgaggccggg
      181 gatgaggctg actatttctg tcaggtgtgg gacagtggta gtgatcatta catcttcggt
      241 gttgggaccc ggctcaccgt cttaggtcag cccaaggctt cccccacggt cactctgttc
      301 ccg
//
LOCUS       KCWK01003925             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12615:14767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003925
VERSION     KCWK01003925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12615:14767"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69663.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          148 c          130 g           95 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cctttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003926             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:24695:9175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003926
VERSION     KCWK01003926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:24695:9175"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69664.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          162 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggagtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003927             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:7526:19682
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003927
VERSION     KCWK01003927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7526:19682"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69665.1"
                     /translation="DYHCQVFDSRDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          159 c          123 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcatcctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactattcc gactcagaca aggaggtggg acctggggtc cccaatcgag
      301 tctctggctc caaggaaacc tcatctaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtttgacag tcgtgatgtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003928             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:11188:14682
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003928
VERSION     KCWK01003928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11188:14682"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69666.1"
                     /translation="DYYCAAWDDSLGGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          158 c          128 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tcgggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca actcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct cccagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcggcatgg gatgatagcc tgggcggtta catcttcggt
      421 ggtgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003929             338 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:21824:18697
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003929
VERSION     KCWK01003929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 338)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21824:18697"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..300
                     /note="immunoglobulin light chain variable region"
     V_region        87..300
     V_segment       87..263
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <228..>272
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69667.1"
                     /translation="DYYCYSSDSSGNWVF"
     J_segment       264..300
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        301..>338
                     /gene="IGLC"
BASE COUNT           64 a          103 c           96 g           75 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatagcct ggattcctct
       61 cctactcccc atcctcactt tctgcacaga agccaggcca gtcccctgtg tcgatcatgt
      121 gtgaggacaa caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      181 cggtggccac cttgactatc agtggggccc aggtggagga tgaatctgac tactactgtt
      241 actcatcaga cagcagtggt aattgggtat tcggcggagg gacccggctg accgtcctag
      301 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003930             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:20525:10349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003930
VERSION     KCWK01003930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20525:10349"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69668.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           84 a          149 c          137 g           93 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcccatgatc tgactcagcc
      121 accctcggtg accgtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tcgaagtgaa gttgtgaact ggtaccagca gaagccagcg caggcccctg tattggtcat
      241 ctttgctgat accgaacggc ccgcagggat ccccgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tccgcggggt cgaggccggg gatgaggctg acttttactg
      361 tcaggtgtgg gacattcgta gtgatcgtcc gctattcggc ggagggaccc ggctcaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003931             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:14585:16842
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003931
VERSION     KCWK01003931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14585:16842"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69669.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          143 c          133 g           95 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gaattgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc aacagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgatagtaga cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003932             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:10921:14434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003932
VERSION     KCWK01003932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:10921:14434"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69670.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          129 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcgac ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003933             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:20810:5462
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003933
VERSION     KCWK01003933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20810:5462"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69671.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          155 c          122 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat gttgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003934             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:23187:2326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003934
VERSION     KCWK01003934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:23187:2326"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..397
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69672.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           94 a          156 c          119 g          106 t
ORIGIN      
        1 acatgggggg gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccaa gcctatgctg actcagccgg cctccctctc
      121 agcatctcct ggagcatcag ccagtctcac atgcaccttc ggcggtggca tcaatgttgc
      181 tggctaccac atacactggt accaacagaa gccagggagt cccccccggt atcttctgag
      241 gtacaaatca gactcagata agggccaggg ctctggagtc accagccgct tctctggatc
      301 caaagatgct tcagcgaaca cagggatttt acgcatctct gggctccagt ctgaggatga
      361 ggctgactat tactgtgcca ttgggcacag cagcggtgat tacatcttcg gtgctgggac
      421 ccgactcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003935             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14085:21985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003935
VERSION     KCWK01003935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14085:21985"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69673.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          152 c          112 g          118 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttggtaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcatc aggggtctgg agtccccagc ctcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003936             490 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:7766:19136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003936
VERSION     KCWK01003936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 490)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7766:19136"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..452
                     /note="immunoglobulin light chain variable region"
     V_region        119..452
     V_segment       119..415
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>424
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69674.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       416..452
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>490
                     /gene="IGLC"
BASE COUNT           92 a          163 c          132 g          103 t
ORIGIN      
        1 acatgggtca acgcagagta catggggagc agagccctga ggagtctgca ccatggcctg
       61 gaccccaatc ctcctcctcc tcctcactct cctccttcac tgcacagggt ctctctccca
      121 gcctgtgctg actcagtcgc cctctgcctc tgcctccctg ggagcctcgg tcaagctcac
      181 ctgcactctg agcagtggac acaggagcta caccatcgcg tggcatcagc agcagcaagg
      241 gaaggcccct cgatacttga tgtggcttaa aagtgatggc agccacagca agggggacgg
      301 gatccctgat cgcttctcag gctccagctc cggggctgag cgctacctca ccatctccaa
      361 cctccagtct gaggatgagg ctgattatta ttgtcagacg tgggatattg gcatttgggt
      421 gttcggcgga gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac
      481 tctcttcccg
//
LOCUS       KCWK01003937             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:22383:9946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003937
VERSION     KCWK01003937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22383:9946"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69675.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          163 c          120 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ccgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003938             358 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15953:11878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003938
VERSION     KCWK01003938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 358)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 358)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..358
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15953:11878"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..320
                     /note="immunoglobulin light chain variable region"
     V_region        7..320
     V_segment       7..282
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <245..>292
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69676.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       284..320
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        321..>358
                     /gene="IGLC"
BASE COUNT           77 a          111 c          101 g           69 t
ORIGIN      
        1 acatgggact cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg
       61 tgggggagac aacattggaa gtcaaagtgt gcactggtac cagcacaagc caccgcaggc
      121 ccctgttctg gtcatctttt attataccga acggccctca ggaatccctg agcgaatctc
      181 tggctccaaa tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga
      241 ggctgactat tactgtcagg tgtgggacac aagtcttgat cacggcttat tcggaggagg
      301 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003939             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:19318:16477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003939
VERSION     KCWK01003939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19318:16477"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..379
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69677.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       391..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          147 c          132 g           97 t
ORIGIN      
        1 acatgggggc tgggtctcag gaggcagcat tgacggtgcc tcagccatgg cctggaccct
       61 tctcctcctc ggcctcctcg ctcactgcac aggctctgcg acctcctttg agctgactca
      121 gccaccctcg gtgtcagcgg cctcaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaatt aaatttgtcc actggtacca gcagaagcca gcgcaggccc ctgtgaaggt
      241 catctatgct gatgacaaac ggccctcagg gatccctgag agattctctg gctccaattc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactattc
      361 ctgtcaggtg tgggacagtg agactgatta ttacatcttc ggttctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003940             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:14946:7121
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003940
VERSION     KCWK01003940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14946:7121"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..441
                     /note="immunoglobulin light chain variable region"
     V_region        108..441
     V_segment       108..404
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69678.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       405..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           85 a          162 c          126 g          106 t
ORIGIN      
        1 acatgggggg ctggggtctc aggaggcagc gctctcggga catctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccctga
      121 ctcagcctcg ctcagtgtct gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga catcggtggt tataactatg tctcctggta ccaacaacat ccaggcacag
      241 cccccaaact cgtgatttat gaggtcaatc agcggccctc aggggtctct gatcgcttct
      301 ctggctccaa gtctgacaac acggcctccc tgaccatctc tggcctccag cctgaggacg
      361 aggctgatta ttactgcagc tcgtatgcag gcagcgacac tttcgtgtta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003941             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:18723:18170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003941
VERSION     KCWK01003941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18723:18170"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69679.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          157 c          124 g          107 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atttccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaagtc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catatacagg catcaacagt tacatcttcg gtggtgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003942             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:12013:5038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003942
VERSION     KCWK01003942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12013:5038"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69680.1"
                     /translation="DYYCQSHDTSSVFF"
     J_segment       395..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           82 a          160 c          124 g          103 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcatctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagcattgac aacagttttg tgtactggta ccagcagcgg ccgggcagcg cccccaccac
      241 tgtgatttac gcagataacc aaagaccctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctgga ctgaagtctg aggacgaggc
      361 tgactactac tgtcagtctc atgacaccag cagtgtgttt ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003943             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:22532:19565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003943
VERSION     KCWK01003943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22532:19565"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69681.1"
                     /translation="DYYCAAWDDGLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          158 c          121 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc aacgtccgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca actccaacat cggaaattat aatgtgtcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatggcc tgagcggtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003944             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:10217:15984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003944
VERSION     KCWK01003944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10217:15984"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69682.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          156 c          124 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgataggc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003945             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:26323:8585
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003945
VERSION     KCWK01003945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:26323:8585"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69683.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          147 c          130 g           97 t
ORIGIN      
        1 atggggctgg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003946             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:12184:3329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003946
VERSION     KCWK01003946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12184:3329"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69684.1"
                     /translation="DYHCQVFDSSDVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tgataaaaac atgtactggt accaacagaa gccagggagc gctcccaaat
      241 tattcctgta ctacttctcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtttgacag tagtgatgtt ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003947             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:16563:16140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003947
VERSION     KCWK01003947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16563:16140"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69685.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          146 c          130 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gtactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaataccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003948             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:17627:17307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003948
VERSION     KCWK01003948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:17627:17307"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..403
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69686.1"
                     /translation="DYYCASYEGGNTFFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          158 c          122 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtaaa attgggtatc gtgatgctgt gtcctggtac caagagcatc caggcaaagc
      241 ccccaaactc ttgatttttg acgtcaataa gcggccctca gggatctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaagatga
      361 ggctgattat tactgcgcct catatgaagg cggcaacact ttcttcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003949             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:12968:19166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003949
VERSION     KCWK01003949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12968:19166"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69687.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          161 c          113 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtccgac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003950             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:15647:6022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003950
VERSION     KCWK01003950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15647:6022"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..297
                     /note="immunoglobulin light chain variable region"
     V_region        5..297
     V_segment       5..260
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <225..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69688.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       263..297
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>335
                     /gene="IGLC"
BASE COUNT           71 a          108 c           86 g           70 t
ORIGIN      
        1 acatggggca gacggtcacc atctcctgta cccgcagcag aggcaacatt gacaatagtt
       61 atgtgcagtg gtaccagcag cgcccgggca gtgccccgac cacagtgatt tacagagata
      121 accaaagagc ctctggggtc cctgatcggt tctctggctc catcgacagc tcctccaact
      181 ctgcctccct caccatctct gggctgaagt ctgaggacga ggctgactac tactgtcagt
      241 ctactgatgg caactacaat cggttattcg gaggagggac ccggctgacc gtcctaggtc
      301 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003951             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:6864:11910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003951
VERSION     KCWK01003951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6864:11910"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69689.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          139 c          140 g           97 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcttcct cggcctcctt gctcacttta caggctctgc ggcctcctat gaggtgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taaaagtgtg cagtggtacc agcagacgcc accgcaggcc cctgtactgg
      241 tcatttatgg tgatagggaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggatagc agtagtaaat atgtattatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003952             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:8764:7908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003952
VERSION     KCWK01003952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:8764:7908"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69690.1"
                     /translation="DYYCQVWDISSDHVLF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          139 c          141 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctccgcggc ctcctttgac ctgactcagc
      121 cacgctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga acttgtgaac tggtaccaac agaggccacc gcaggcccct gtgctggtca
      241 tgtatgctga tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaatacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacattagt agtgatcatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003953             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:20962:14823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003953
VERSION     KCWK01003953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20962:14823"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69691.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       384..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           89 a          142 c          125 g          102 t
ORIGIN      
        1 atgggggtgg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagccgg ccaggatcac ctgctctgga gatgtattgc
      181 caaaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgta ttggtcatct
      241 ctgaggacac caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcagcaga cagtagtggt catggcttct tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003954             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:13221:19777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003954
VERSION     KCWK01003954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13221:19777"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..436
                     /note="immunoglobulin light chain variable region"
     V_region        108..436
     V_segment       108..402
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69692.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       403..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           81 a          165 c          116 g          114 t
ORIGIN      
        1 acatgggggg ctggggtctc agaaggcagc gctctcagga cgtctccacc atggcctgga
       61 ctctgctcct cgtcaccctc ctcactcaag gcacaggatc ctgggctcag tctgccccga
      121 ctcagcctcc ctctgtgtct gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga cgttggtggt tctaactctg tctcctggta ccaacaacac ccaggcagag
      241 cccccaaact catgattttt ggtgtcaata atcggccctc tggggtctct gaccgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tggcctccag tctgaggacg
      361 aggctgatta ttactgttgt tcacattcaa ccagtagcac ttacgtcttc ggtcctggga
      421 cccggctcac cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01003955             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:22249:9901
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003955
VERSION     KCWK01003955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22249:9901"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..275
                     /note="immunoglobulin light chain variable region"
     V_region        8..275
     V_segment       8..236
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <206..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69693.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       238..275
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>313
                     /gene="IGLC"
BASE COUNT           65 a           90 c           85 g           73 t
ORIGIN      
        1 acatggggac ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag
       61 cgctcccagg ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt
      121 ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc
      181 tgggctccag cctgaggacg aggccgatta tttctgccag gtgtttgaca gtagtgttgt
      241 gttcttcgga ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt
      301 cactctcttc ccg
//
LOCUS       KCWK01003956             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16211:14691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003956
VERSION     KCWK01003956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16211:14691"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69694.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          151 c          121 g          111 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgt cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003957             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:6941:4963
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003957
VERSION     KCWK01003957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:6941:4963"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..407
                     /note="immunoglobulin light chain variable region"
     V_region        87..407
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69695.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       372..407
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>446
                     /gene="IGLC"
BASE COUNT           91 a          141 c          117 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aagatcacct gctctggaga tgcactgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcgat gaggacacca
      241 aacggccctc tgggatccct gggagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gcagtggtta tggcttattc ggaggaggga cccggctgac cgtcctacgt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003958             299 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:21856:8951
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003958
VERSION     KCWK01003958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 299)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21856:8951"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..261
                     /note="immunoglobulin light chain variable region"
     V_region        6..261
     V_segment       6..225
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>233
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69696.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       229..261
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        262..>299
                     /gene="IGLC"
BASE COUNT           67 a           84 c           88 g           60 t
ORIGIN      
        1 acatgggggg agacaacatt ggaattaaaa ctgtacactg gtaccagcag aagccaccgc
       61 agggccctgt attggtcatc tttgctgata gtaagcggcc ctcagggatc cctgagcgat
      121 tctctggctc caactcaggg aacaccgcca ccctgaccat cagcagggtc gaggccgggg
      181 atgaggctga ctattactgt caggtgtggg acagtagtag taaatggata ttcggcgggg
      241 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003959             369 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:13245:14377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003959
VERSION     KCWK01003959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 369)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13245:14377"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..331
                     /note="immunoglobulin light chain variable region"
     V_region        115..331
     V_segment       115..291
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <259..>303
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69697.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       294..331
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        332..>369
                     /gene="IGLC"
BASE COUNT           70 a          120 c           93 g           86 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 cgatatcttc tgagatacaa atcggactca gataagggcc agggctctgg agtccccagc
      181 cgcttctctg gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc
      241 cagtctgagg atgaggctga ctattactgt gccattggac acagcagcgg tgattacatc
      301 ttcggtgctg ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact
      361 ctgttcccg
//
LOCUS       KCWK01003960             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:12102:8965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003960
VERSION     KCWK01003960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12102:8965"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69698.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          158 c          117 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcggactca gataagggcc aggcctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tgattacatc ttcggtgctg
      421 ggtcccgact caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003961             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:14739:6124
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003961
VERSION     KCWK01003961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14739:6124"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69699.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       394..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          140 c          137 g          103 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactttac aggctctgtg gcctcctatg agttgcctca
      121 gccacgctca gtgtccgtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt aatagtgtgc attggtacca gcagaagcca ccgcgggccc ctgtattggt
      241 catctctgtt gatagcgaac ggccctcagg gatccctgag cgattctctg gttctagatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggataata tttataaata cgcggtattc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003962             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:22040:14153
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003962
VERSION     KCWK01003962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22040:14153"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..278
                     /note="immunoglobulin light chain variable region"
     V_region        8..278
     V_segment       8..241
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <203..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69700.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       242..278
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>316
                     /gene="IGLC"
BASE COUNT           62 a          100 c           82 g           72 t
ORIGIN      
        1 acatgggtcc tgttcgggaa gcagctccaa catcggaagt catagtgtct cctggtacca
       61 gcaactccca ggaacagctc ccaaactcct catctattat agtgatcaac gagcctcagg
      121 tgtctctgac cgattctctg gctcccagtc tggcacgtca gcctccctgg ccatcagtgg
      181 gctccagacc gaggatgagg ctgattatta ctgcgcggca tgggatgata gcctgagcgg
      241 ttacatcttc ggtggtggga cccggctcac cgtcctaggt cagcccaagg cttcccccac
      301 ggtcactctg ttcccg
//
LOCUS       KCWK01003963             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:7526:18379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003963
VERSION     KCWK01003963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7526:18379"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69701.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          155 c          125 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccggaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgataggt tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01003964             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:18842:10593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003964
VERSION     KCWK01003964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18842:10593"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69702.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          139 c          137 g           99 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagg
      121 caccctcgat ttcagtgtcc cccggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtgaac tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tgtatgctga tagcgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacatgaat agtcatcatc tattattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003965             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:17099:13779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003965
VERSION     KCWK01003965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17099:13779"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69703.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          148 c          131 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccgatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta agagtgtgca ctggtaccaa cacaagccac cgcaggcccc tatcctggtc
      241 gtctattatt ataccgaacg gccctcggcg atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacactac tattgatcat ggctttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003966             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12799:19960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003966
VERSION     KCWK01003966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12799:19960"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69704.1"
                     /translation="DYYCQVWDISTDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          145 c          133 g          101 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gcctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccaggg tcacctgtgg aggagacaac
      181 cttggatatg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctaacc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattag tactgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003967             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:24978:20792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003967
VERSION     KCWK01003967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24978:20792"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69705.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccatgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003968             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:16728:7812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003968
VERSION     KCWK01003968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:16728:7812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69706.1"
                     /translation="DYYCQVWDIYSDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          141 c          135 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gaggcaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tgctggtcat
      241 ctttgctgat tatgaacggc cctcagggat ccctaagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata gtgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003969             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:16059:9843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003969
VERSION     KCWK01003969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16059:9843"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69707.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          120 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcatg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003970             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:21099:16432
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003970
VERSION     KCWK01003970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:21099:16432"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69708.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       398..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          164 c          124 g          101 t
ORIGIN      
        1 acatggggga gcagagccct gaggagtctg caccatggcc tggaccccaa tcctcctcct
       61 cctcctcact ctcctccttc actgcacagg gtctctctcc cagcctgtgc tgactcagtc
      121 gccctctgcc tctgcctccc tgggagcctc ggtcaagctc acctgcactc tgagcagtgg
      181 ccactacagc tacaccatcg catggcatca gcagcagcaa gggaaggccc ctcggttctt
      241 gatgtggctt aagagtgatg gcagccacac caagggggac ggggtccctg atcgcttctc
      301 aggctccagc tccggggctg agcgctacct caccatctcc aacctccagt ctgaggatga
      361 ggctgattat tactgtcaga cctgggatat tggcatttgg gtattcggcg gagggacccg
      421 gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01003971             281 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:27051:8742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003971
VERSION     KCWK01003971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 281)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:27051:8742"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    17..243
                     /note="immunoglobulin light chain variable region"
     V_region        17..243
     V_segment       17..206
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <168..>215
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69709.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       207..243
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        244..>281
                     /gene="IGLC"
BASE COUNT           51 a           89 c           74 g           67 t
ORIGIN      
        1 acatgggtct cctgttctgg aagcagcagc tcccaggaac agctcccaaa ctcctcatct
       61 attatagtga tcaacgagcc tcaggtgtct ctgaccgatt ctctggctct cagtctggca
      121 cgtcagcctc cctggccatc agtgggctcc aggccgagga tgaggctgat tattactgcg
      181 cagcatggga tgatagtctg agcggttaca tcttcggtgc tgggacccgg ctcgccgtcc
      241 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01003972             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:19543:4739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003972
VERSION     KCWK01003972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19543:4739"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69710.1"
                     /translation="DYSCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           98 a          162 c          111 g          108 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagttacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaaa tacttcaacg aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctattcctgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003973             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:9218:10217
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003973
VERSION     KCWK01003973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9218:10217"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69711.1"
                     /translation="DYYCQVWGSRSDHPVF"
     J_segment       391..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          148 c          135 g           94 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagt ctctgcgacc tcctatgaac tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccagggtc acctgtgggg caggtaacat
      181 tggaagtaat tttgttcact ggtaccagca gaagccaccg caggcccctg ttcaggtcat
      241 ctatgcagat aacagacggc cctcagggat ccctgagcga ttctctggct ccaattcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg ggcagtcgta gtgatcatcc ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003974             328 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:12183:10611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003974
VERSION     KCWK01003974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 328)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12183:10611"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..290
                     /note="immunoglobulin light chain variable region"
     V_region        8..290
     V_segment       8..252
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>262
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69712.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       254..290
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        291..>328
                     /gene="IGLC"
BASE COUNT           72 a           99 c           93 g           64 t
ORIGIN      
        1 acatggggga cagacggcca ggatcacctg tgggggagac aacattggaa gtcaaagtgt
       61 acactggtac cagcacaagc caccgcaggc ccctgttctg ctcatctttt attataccga
      121 acggccctca ggaatccctg agcgattctc tggctccaaa tcagggaaca ccgccaccct
      181 gaccatcagc ggggtcgagg ccggggatga ggctgactat tactgtcagg tgtgggacac
      241 aactattgat cacggcttgt tcggaggagg gacccggctg accgtcctag gtcagcccaa
      301 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003975             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17345:12618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003975
VERSION     KCWK01003975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17345:12618"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..213
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69713.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       219..251
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           59 a           86 c           89 g           55 t
ORIGIN      
        1 acatggggga agtgaagttg tgaactggta ccagcagaag ccagcgcacg cccctgtgct
       61 ggtcatctat gctaatagcg aacggccctc agggatccct gagcgattct ctggctccaa
      121 atcagggaac acggccaccc tgaccatcag cggggtcgag gccgggggtg aggctgacta
      181 ttactgtcag gtgtgggaca tgcgtagtga tcaaccgcta ttcggcggag ggacccggct
      241 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003976             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:5633:15034
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003976
VERSION     KCWK01003976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5633:15034"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..439
                     /note="immunoglobulin light chain variable region"
     V_region        93..439
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69714.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>479
                     /gene="IGLC"
BASE COUNT           92 a          163 c          110 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtcctg ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003977             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:12031:6482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003977
VERSION     KCWK01003977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12031:6482"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69715.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       412..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           91 a          155 c          128 g          113 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg agcagctcca acattggagg ttattatgtg cagtggtacc agcagcttcc
      241 aggaacggcc cccaaactcc tcatctatga aaatgataaa cgaccctcag gggtttctga
      301 tcgattctct ggctcccagt ctgattcctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agcttgagtg ttgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01003978             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:9883:20041
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003978
VERSION     KCWK01003978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:9883:20041"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69716.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       407..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           96 a          156 c          118 g          110 t
ORIGIN      
        1 acatggggag ccccagctct ggagccaggg atcccttcca atatcagcac catggcctgg
       61 actctgctcc tcctccagtt cctcctcact tgctgcccag ggtccaattc tcaggctgta
      121 gtgactcagg agccctcaat gactgtgtcc ccaggaggga cagtcactct cacctgtgct
      181 tccagcactg gagcagtcac cagtggtcac tctccacact ggttccagca gaaacctgga
      241 caagccccca agacactgat ttataataca aactacagac actcctggac tcctgcccgg
      301 ttctcaggct ccctccttgg gggtaaagct gccctgacac tgtcaggtgc gcagcctgag
      361 gatgaggctg agtattattg tttactgtac tatagtggtg ctcagctgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01003979             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:20122:7196
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003979
VERSION     KCWK01003979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20122:7196"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69717.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          163 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcccgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01003980             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:25406:4704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003980
VERSION     KCWK01003980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:25406:4704"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..394
                     /note="immunoglobulin light chain variable region"
     V_region        76..394
     V_segment       76..362
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69718.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       363..394
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>432
                     /gene="IGLC"
BASE COUNT           88 a          133 c          115 g           96 t
ORIGIN      
        1 acatggggtg tctccaccat ggcctggact cctctctggc tcaccctcct cagtctttgc
       61 acaggttctg tggtttcttc tgagctgact caggaccctg cagtgtctgt ggccttggga
      121 cagacagtca ggatcacctg ccaaggagac agcctcagaa gttattatgc aagttggtac
      181 cagcagaagc caggccaggc ccctatactg gtcgtctatg gtaacaatta ccggccctca
      241 gggatcccag agcgattctc tggctccagt acacgaaaca cagcttcctt gaccatcact
      301 ggggctcagg tggaagatga ggctgactat tactgtgact cctgggacag ccgcggaacc
      361 caattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      421 actctcttcc cg
//
LOCUS       KCWK01003981             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:6168:19872
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003981
VERSION     KCWK01003981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:6168:19872"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..418
                     /note="immunoglobulin light chain variable region"
     V_region        97..418
     V_segment       97..381
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <346..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69719.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       382..418
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>456
                     /gene="IGLC"
BASE COUNT           89 a          143 c          123 g          101 t
ORIGIN      
        1 acatgggggc tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta
       61 ctccccatcc tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc
      121 tcggtgtcag tgtccccagg acagccggcc aggatcacct gctctggaga tgtattgcca
      181 aaaaaatatg cttattggtt ccagcagaag ccaggccagt cccctgtatt ggtcatctct
      241 gaggacaccg aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca
      301 gtggccacct tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac
      361 tcagcagaca gtagtggtca tggcttcttc ggaggaggga cccggctgac cgtcctaggt
      421 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01003982             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:18685:13694
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003982
VERSION     KCWK01003982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18685:13694"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69720.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          143 c          134 g          102 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtcaac tggtaccaac agaagccacc gcaggcccct gtggtggtca
      241 tctatgctga ttatgaacgg ccctcaggga tccctgaccg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcggag tcgcggccgg ggatgaggct gactattact
      361 gtcaggtttg ggacatttat actgatcatc cggtgttgtt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003983             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:16317:10957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003983
VERSION     KCWK01003983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16317:10957"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69721.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       411..448
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           96 a          157 c          124 g          109 t
ORIGIN      
        1 acatggggag cgcagcttca gctgtgggta cagaaggcag gactcaggac aatctccagc
       61 atggcctggt tccctctcgt cctcaccctc ctcactcact gtgcagggtc ctgggcccag
      121 tctgtgctga ctcagcctcc ctcagcgtct gaggccgcca ggaagagtgt caccatctcc
      181 tgttctggaa gcagctccaa catcggaagt aataatgtgt cctggtacca gcacctccca
      241 ggaacagctc ccaaactcct catctattat aatgatcaac gaggctcagg tgtctctgac
      301 cgattctctg gctccaagtc tggcacgtca gcctccctgg ccatcagtgg gctccagacc
      361 gaggatgagg ctgattatta ctgcgcagcg tgggatgata gcctgagtag ttacatcttc
      421 gctgctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      481 ttcccg
//
LOCUS       KCWK01003984             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:16571:20363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003984
VERSION     KCWK01003984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16571:20363"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69722.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       392..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          155 c          118 g          102 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctcgtc tcctctcctc
       61 ctcacccttt tcattcactg cacagggtcc tgggcccagt ctgtgctgac acagccgccc
      121 tcagtgtctg gggccccagg gcagagggtc accatctcct gcactgggag cagctccaac
      181 attggaggtt attatatatc ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 gtctatgaca ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggttcctcag ccaccctgac catcactggg ctccagactg aggatgaggc tgattattac
      361 tgccagtcct atgacagcag tctgagtgct cgggtattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01003985             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:22712:3913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003985
VERSION     KCWK01003985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22712:3913"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69723.1"
                     /translation="DYSCQVWDSESDYYIF"
     J_segment       379..416
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           89 a          143 c          129 g           93 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacccttc tcctcctcgg
       61 cctcctcgct cactgcacag gctctgcgac ctcctttgag ctgactcagc caccctcggt
      121 gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca ttggaattaa
      181 atttgtccac tggtaccagc agaagccagc gcaggcccct gtgaaggtca tctatgctga
      241 tgacaaacgg ccctcaggga tccctgagag attctctggc tccaattcag ggaacaccgc
      301 caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattcct gtcaggtgtg
      361 ggacagtgag agtgattatt acatcttcgg tgctgggacc cggctcaccg tcctaggtca
      421 gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01003986             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:19572:13682
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003986
VERSION     KCWK01003986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:19572:13682"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..444
                     /note="immunoglobulin light chain variable region"
     V_region        96..444
     V_segment       96..407
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69724.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           96 a          165 c          112 g          109 t
ORIGIN      
        1 acatggggcc cactgtgggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctccaagcc tatgctgact cagccggcct
      121 ccctctcagc aactcctgga gcatcagcca gtctcacatg caccttcagc ggtggcatca
      181 atgttgctgc ctaccacata cactggtacc agcagaagcc agggagtccc ccccggtatc
      241 ttctgagtta caaatcagac tcagataagg gccagggctc tggagtcccc agccgcttct
      301 ctggatccaa aaatgcttca acgaacacag gcattttaca catctctggg ctccagtctg
      361 aggatgaggc tgactatttc tgtgccattg gacacagcag cggtccttac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01003987             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:7084:2736
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003987
VERSION     KCWK01003987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7084:2736"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..417
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69725.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       418..454
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           97 a          159 c          125 g          111 t
ORIGIN      
        1 acatgggggg gtgaagcgca gcttcagctg tgggtacaga aggcaggact caggacaatc
       61 tccagcatgg cctggttccc tctcctcctc accctcctca ctcactgtgc agggtcctgg
      121 gcccagtctg tgctgactca gcctccctca gcgtctgagg ccgccgggaa gagtgtcacc
      181 atctcctgtt ctggaagcag ttccaacatc ggaagtaaca gtgtatcctg gtaccaacaa
      241 ctcccagaaa cgactcccaa actcctcatc tattataatc atcggcgagc ctcaggtgtc
      301 tctgaccgat tctctggctc caagtctggc acttcagcct ccctggccat cagtgggctc
      361 cagaccgagg atgaggctga ttattactgc gcagtatggg atgatagcct gaccggttac
      421 atcttcggtg ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCWK01003988             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:16067:18291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003988
VERSION     KCWK01003988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:16067:18291"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69726.1"
                     /translation="DYYCSSYAGCDTFVSF"
     J_segment       404..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           85 a          162 c          125 g          106 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc gtgatttatg aggtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct ggcctccagc ctgaggacga
      361 ggctgattat tactgcagct catatgcagg ctgcgacact ttcgtgtcat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003989             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:10983:13565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003989
VERSION     KCWK01003989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10983:13565"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..431
                     /note="immunoglobulin light chain variable region"
     V_region        104..431
     V_segment       104..397
                     /gene="IGLV8-111"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69727.1"
                     /translation="DYYCTLYMGSGVLF"
     J_segment       398..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           93 a          151 c          118 g          107 t
ORIGIN      
        1 acatggggaa gcctgagagc acttggcctt cataagtgtc cccaccatgg cctggatgat
       61 gcttctcctc ggactccttg cttatggctc aggagtggat tctgagactg tggtgaccca
      121 ggagccatca ttgtcagtgt cccctggagg aacagtcaca ctcacctgtg gcctgagctc
      181 tggctcagtc tctatcacta actaccccag ctggtaccag cagaccccag gccaggctcc
      241 acgcacgctc gtctacagaa caaacactca cccttctggg gtccctgatc gcttctctgg
      301 ctccatcctt gggaacaaag ctgccctcac catcacgggg gctcaggcag acgatgaatc
      361 tgattattac tgcacactct acatgggtag tggcgtttta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003990             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:20059:10213
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003990
VERSION     KCWK01003990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20059:10213"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..373
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69728.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       382..416
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           86 a          147 c          130 g           91 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacccttc tcctcctcgg
       61 cctcctcgct cactgcacag gctctgcgac ctcctatgag ctgactcagc caccctcggt
      121 gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca ttggaactaa
      181 atatgtgcac tggtaccagc agaagccagc gcaggcccct gtgttggtca tctatgctga
      241 taccagacgg ccctcaggga tccctgagcg attctctggc tccaactcag ggaacaccgc
      301 caccctgacc atcaccgggg tcgaggccgg gtatgaggct gactatttct gtcaggtttg
      361 ggacgatagt agtgatcatc cggtattcgg cggagggacc cggctgaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01003991             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:26128:12516
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003991
VERSION     KCWK01003991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:26128:12516"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..428
                     /note="immunoglobulin light chain variable region"
     V_region        105..428
     V_segment       105..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69729.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       393..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>467
                     /gene="IGLC"
BASE COUNT           91 a          148 c          130 g           98 t
ORIGIN      
        1 acatgggggc ctgggcctca ggaggcagca ttgacggtgc ctcagccatg gcctggactt
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggcctcctat gatctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag tcaaagtgtg cactggtacc agcacaagcc accgcaggcc cctgttctgg
      241 tcatctttta ttataccgaa cggccctcag gaatccctga gcgaatctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacaca agtcttgatc acggcttatt tggaggaggg acccggctga
      421 ccgtcctaag tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01003992             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:4927:16998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003992
VERSION     KCWK01003992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:4927:16998"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..441
                     /note="immunoglobulin light chain variable region"
     V_region        96..441
     V_segment       96..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69730.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          165 c          109 g          113 t
ORIGIN      
        1 acatggggcc cactgcaggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcccagcc tgtgctgacc cagccaacct
      121 ccctctcagc atctccggga acatcagcca gactcagctg caccttgagc agtggcaatg
      181 ttggtagtta cagcattttc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tttactacta ctcagactca agtaaccacc aggactctgg agtccccagc cgcttctctg
      301 gttcgaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccacatggc acagcagcgc ttcttacatc ttcggtcctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01003993             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14113:22972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003993
VERSION     KCWK01003993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14113:22972"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69731.1"
                     /translation="DYYCALWHSSAIWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          161 c          112 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt cctgtcccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagac tcagttgcac cttgaacagc ggcatcaatg
      181 ttggtagtta caccatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 ttcactacta ctcagactca agtaatcacc agggctctgg tgtccccagc cgcttctctg
      301 gatccaaaga tgtttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccctatggc acagcagcgc tatttgggta ttcggcggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01003994             355 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:12735:5456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003994
VERSION     KCWK01003994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 355)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12735:5456"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..317
                     /note="immunoglobulin light chain variable region"
     V_region        89..317
     V_segment       89..277
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <245..>289
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69732.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       284..317
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        318..>355
                     /gene="IGLC"
BASE COUNT           69 a          113 c           91 g           82 t
ORIGIN      
        1 acatgggggg gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccaa gccagggagt cccccccggt atcttctgag
      121 gtacaaatca gactcagata agggccaggg ctctggagtc cccagccgct tctctggatc
      181 caaagatgct tcagcgaaca cagggatttt acgcatatct ggactccagt ctgaggatga
      241 ggctgactat tactgtgcca ttggacacag cagcggtgat tatatcttcg gtgctgggac
      301 ccgtctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01003995             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:9809:15934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003995
VERSION     KCWK01003995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9809:15934"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69733.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          147 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctttgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01003996             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:24875:5800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003996
VERSION     KCWK01003996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24875:5800"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69734.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           92 a          160 c          109 g          113 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtactga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttga gcagtggcat caatgttggt
      181 agttacagcg tattctggta ccagcagaag ccagggagtc ctccccggtt ccttctgtac
      241 tactactcag actcaagtaa acaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cggccaatgc aggcctttta ctgatctcta ggctccagtc tgaagatgag
      361 gctgactatt actgtgccat atggcacagc agcgcttctt acttcttcgg tactgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01003997             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:6013:13101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003997
VERSION     KCWK01003997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6013:13101"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..380
                     /note="immunoglobulin light chain variable region"
     V_region        87..380
     V_segment       87..343
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>352
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69735.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       345..380
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        381..>418
                     /gene="IGLC"
BASE COUNT           80 a          125 c          127 g           86 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagt gtccccagga cagacggcca gggtcacctg
      121 tgggggagac aacatcggag gtgaagttgt gaattggtac cagcagaagc caccgcaggc
      181 ccctgtgttg gtcatctatg ctgatagcga gcggccctca gggatccctg agcgattctc
      241 tggctccaaa tcagggaaca cggccaccct gaccatcagc ggggtcgagg ccggagatga
      301 ggctgactac tactgtcagg tgtgggacct taatagtcat catctgttat tcggaggagg
      361 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01003998             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:9221:4166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003998
VERSION     KCWK01003998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9221:4166"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69736.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          164 c          123 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggat ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01003999             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:17381:3804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01003999
VERSION     KCWK01003999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17381:3804"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69737.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          139 c          136 g           99 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 cagcctcggt gtcagtgtcc ccgggacaga cggccaggat cacctgtggg ggagacaata
      181 ttggaagtaa aaatgtgcac tggtaccagc aggagccacc gcaggcccct gtgttggtca
      241 tcttttatga taacaaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacatcgc caccctgacc atcagcgagg ccgaggccgg ggatgaggct gactattact
      361 gtcagctgtg ggacagtagt gttgatcatg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004000             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:17180:17109
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004000
VERSION     KCWK01004000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17180:17109"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69738.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       406..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           88 a          159 c          128 g          103 t
ORIGIN      
        1 acatgggcct ggctgtggct caggaagcag agcctggagc gtctccacca tggcctgggc
       61 tccactcctc ctcaccctcc tcgctcactg cacagggtct tgggctgagg ttctgttcac
      121 gcagccccat tctgtgtcgg ggtctccggg gcagacggtc accatctcct gtacccgcag
      181 cagaggcaac attgacaata gttatgtgca gtggtaccag cagcgcccgg gcagtgcccc
      241 gaccacagtg atttacagag ataaccaaag agcctctggg gtccctgatc ggttctctgg
      301 ctccatcgac agctcctcca actctgcctc cctcaccatc tctgggctga agtctgagga
      361 cgaggctgac tactactgtc agtctactga tggcaactac aatcggttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004001             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:22385:9502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004001
VERSION     KCWK01004001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22385:9502"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..395
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69739.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       399..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           86 a          156 c          123 g          105 t
ORIGIN      
        1 acatggggtg tggctcagga agcagagcct ggagcatctc caccatggcc tgggctccac
       61 tcctcctcac cctcctcgct cactgcacag ggtcttgggc tgaggttgtg ttcactcagc
      121 cccattctgt gtcggggtct ccggggcaga cggtcaccat ctcctgcacc cgcagcagtg
      181 gcagcattga caacggcttt gtgtactggt accagcagcg gccgggcagc gctcccacca
      241 ctgtgattta caaagataac caaagaccct ctggggtccc tgatcggttc tctggctcca
      301 tcgacagctc ctccaactct gcctccctca ccatctctgg actgaaatct gaggacgagg
      361 ctgactatta ctgtcagtct tatgacagca gcagtgtatt attcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004002             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:19533:2844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004002
VERSION     KCWK01004002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19533:2844"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..444
                     /note="immunoglobulin light chain variable region"
     V_region        97..444
     V_segment       97..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69740.1"
                     /translation="DYFCAIGHSSGNYIF"
     J_segment       407..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          157 c          123 g          111 t
ORIGIN      
        1 acatggggcc cactgtgggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctccgagcc tatgctgact cagccggcct
      121 ccctctcagc atctcctgga gcatcagcca gtctcacatg taccttcagc ggtggcatca
      181 atgttgctgg ctaccacata tactggtacc agcagaagcc agggagtccc ccccggtatc
      241 ttctgaggta cagatcagag tcagataagg gccagggctc tggagtcccc agccgcttct
      301 ctggatccaa agatgcttca gcgaacacag ggattttacg catctctggg ctccagtctg
      361 aggatgaggc tgactatttc tgtgccattg ggcacagcag cggtaattac atcttcggtg
      421 gtgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01004003             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:25170:14070
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004003
VERSION     KCWK01004003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:25170:14070"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69741.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          165 c          123 g          106 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctccctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004004             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:14235:4385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004004
VERSION     KCWK01004004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14235:4385"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..255
                     /note="immunoglobulin light chain variable region"
     V_region        8..255
     V_segment       8..219
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <183..>227
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69742.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       223..255
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        256..>293
                     /gene="IGLC"
BASE COUNT           64 a           86 c           85 g           58 t
ORIGIN      
        1 acatgggcaa cattggaact aaaactgtgc actggtacca gcagaagcca ccgcagggcc
       61 ctgtattggt catctttgct gacagtaaac ggccctcagg gatccctgag cgattctctg
      121 gctccaactc agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg
      181 ctgactatta ctgtcaggtg tgggacagta gtagtaaatg gatattcggc ggggggaccc
      241 ggctaaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004005             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:23872:11554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004005
VERSION     KCWK01004005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:23872:11554"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69743.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          137 c          135 g          104 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacatggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004006             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:13581:3777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004006
VERSION     KCWK01004006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13581:3777"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69744.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          160 c          112 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004007             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:16556:14451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004007
VERSION     KCWK01004007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16556:14451"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69745.1"
                     /translation="DYYCQVYDSSTNTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           92 a          164 c          122 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtaccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004008             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:25837:12742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004008
VERSION     KCWK01004008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25837:12742"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69746.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          162 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttgttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004009             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:10430:9289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004009
VERSION     KCWK01004009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10430:9289"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69747.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          162 c          120 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcaatattg gcaataaaaa catgtactgg taccagcaga agccagggag cgctcccaag
      241 ttattcctgt actactactc cgactcagac atgcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtcat acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctgt attattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004010             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:23786:12907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004010
VERSION     KCWK01004010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23786:12907"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69748.1"
                     /translation="DYYCQVWDNIYKYAIF"
     J_segment       397..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          138 c          137 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 aggcacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaaa
      181 aaattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcgatatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004011             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12081:23708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004011
VERSION     KCWK01004011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12081:23708"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..382
                     /note="immunoglobulin light chain variable region"
     V_region        58..382
     V_segment       58..333
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <307..>354
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69749.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       345..382
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>420
                     /gene="IGLC"
BASE COUNT           83 a          135 c          115 g           87 t
ORIGIN      
        1 acatggggga cccttctcct cctcggcctc ctcgctcact gcacaggctc tgcgacctcc
       61 tttgagctga ctcagccacc ctcggtgtca gcggcctcag gacagacggc caggatcacc
      121 tgtgggggag acaacattgg aattaaattt gtccactggt accagcagaa gccagcgcag
      181 gcccctgtga aggtcatcta tgctgatgac aaacggccct cagggatccc tgagagattc
      241 tctggctcca attcagggaa caccgccacc ctgaccatca gcggggtcga ggccggggat
      301 gaggctgact attcctgcca ggtgtgggac agtgagactg attattacat cttcggttct
      361 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004012             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:11775:6891
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004012
VERSION     KCWK01004012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11775:6891"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69750.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          155 c          119 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttcgggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag caactcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctcccagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcggcat gggatgatag cctgagcggt tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004013             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:12738:14789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004013
VERSION     KCWK01004013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:12738:14789"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69751.1"
                     /translation="DYYCQVWDTSIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          147 c          127 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtga gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tatactggtc
      241 atcttttatt atactgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggc gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004014             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:19185:10426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004014
VERSION     KCWK01004014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19185:10426"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69752.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          161 c          119 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctctgcatc tcctggagct tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatataa atcagactca gatgaggacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcctcagcg aacacggggc ttttgcgcat ctctgggctc cagtctgagg
      361 atgaggcgga ctactactgt gccattggac acagcagcgg tgattacatc ttcggtgctg
      421 ggacccgcct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004015             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:13098:14805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004015
VERSION     KCWK01004015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13098:14805"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69753.1"
                     /translation="DYYCQVWDTTLDHGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          149 c          130 g           98 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt caaagtgtgc actggtacca gcacaagcca ccgcaggccc ctgttctggt
      241 catcttttat tataccgaac ggccctcagg aatccctgag cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacacaa ctcttgatca cggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004016             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:19016:15182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004016
VERSION     KCWK01004016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19016:15182"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69754.1"
                     /translation="AYYCQVWDGDSDHYIF"
     J_segment       389..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          148 c          129 g           94 t
ORIGIN      
        1 acatggggtg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag actctgcgac ctcctatgag ctgactcagc
      121 caccctcggt gtcaacggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa ttttgtgcac tggtaccagc agaagccagc gcaggcccct atgcaggtca
      241 tctatgctga taacaaacgg ccctcaggga tccctgagag attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcggag tcgaggccgg ggatgaggct gcctattact
      361 gtcaggtgtg ggacggtgat agtgatcatt acatcttcgg tgctgggacc cggctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004017             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:15769:2919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004017
VERSION     KCWK01004017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15769:2919"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69755.1"
                     /translation="DYFCQVWDDTSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          150 c          136 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacagc
      181 attggaacta aatatgtgca ctggtaccag cagaagccag ggcaggcccc tgtgttggtc
      241 atctatgctg acaccagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggt gtcgaggccg ggtatgaggc tgactatttc
      361 tgtcaggtgt gggacgatac tagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004018             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:25573:6229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004018
VERSION     KCWK01004018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25573:6229"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69756.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           83 a          145 c          137 g           99 t
ORIGIN      
        1 acatgggctg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtccgtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttcgaagtga agttgtgaac tggtaccagc agaagccagc gcaggcccct gtgttggtca
      241 tctttgctga taacgaacgg ccctcaggga tccctgagcg attctctggc ttcaaatcag
      301 ggaacacggc caccctgacc atccgcgggg tcgaggccgg ggatgaggct gacttttact
      361 gtcaggtgtg ggacattcgt agtgatcgtc cgctattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004019             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:21758:18050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004019
VERSION     KCWK01004019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21758:18050"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69757.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          160 c          120 g          107 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc gtcaatgtgg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctgt
      241 actaccagtc agactcaagg aagcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggctgt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc ctatggcaca gcagcgcttc ttgcatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004020             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:21913:3179
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004020
VERSION     KCWK01004020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:21913:3179"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69758.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          165 c          124 g          108 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcgtcccc gggagcatcg gccagactcc cctgcaccct gaccagtgac
      181 ctcagcgttg gtagtaaaaa catgtattgg taccagcaga agccagggag cgctcccagg
      241 tcattcctct actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgacta ttactgtcag gtgtatgaca gtagtgctaa tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004021             277 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:6767:12341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004021
VERSION     KCWK01004021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 277)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6767:12341"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..239
                     /note="immunoglobulin light chain variable region"
     V_region        9..239
     V_segment       9..202
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <164..>211
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69759.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       204..239
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        240..>277
                     /gene="IGLC"
BASE COUNT           56 a           91 c           69 g           61 t
ORIGIN      
        1 acatgggata tcctggtacc agcagctccc aggaacggcc cccaaactcc tcgtctatga
       61 caataataag cgaccctcag gggtttctga ccgattctct ggctccaagt ctggttcctc
      121 agccaccctg accatcactg ggctccagac tgaggatgag gctgattatt actgccagtc
      181 ctatgacagc agtctgagtg ctcgggtatt cggcggaggg acccggctaa ccgtcctagg
      241 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004022             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:22764:6406
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004022
VERSION     KCWK01004022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22764:6406"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69760.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 ttagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004023             392 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:18587:3393
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004023
VERSION     KCWK01004023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 392)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18587:3393"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    33..354
                     /note="immunoglobulin light chain variable region"
     V_region        33..354
     V_segment       33..318
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <282..>326
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69761.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       322..354
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        355..>392
                     /gene="IGLC"
BASE COUNT           85 a          117 c          112 g           78 t
ORIGIN      
        1 acatgggcgc ttactgcaca ggctctgcga cctcctatga attgactcag tcaccctcag
       61 tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac attggaacta
      121 aaactgtgca ctggtaccaa cagaagccac cgcagggccc tgtattggtc atctttgctg
      181 atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca gggaacaccg
      241 ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac tgtcaggtgt
      301 gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc ctaggtcagc
      361 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004024             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:21908:14470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004024
VERSION     KCWK01004024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21908:14470"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..396
                     /note="immunoglobulin light chain variable region"
     V_region        80..396
     V_segment       80..366
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <329..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69762.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       367..396
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        397..>436
                     /gene="IGLC"
BASE COUNT           84 a          136 c          120 g           96 t
ORIGIN      
        1 acatgggggg ggtgtctcca ccatggcctg gactcctctc tggctcaccc tcctcagtct
       61 ttgcacaggt tctatggttt cttctgagct gactcaggac cctgcagtgt ctgtggcctt
      121 gggacagaca gtcaggatta cctgccaagg agacagcctc agaagctctt atgcaagctg
      181 gtaccaacag aggccaggcc aggcccctgt gctggtcgtc tatggtaaca actaccggcc
      241 ctcagggatc ccagagcgat tctctggctc ctactcacga aacacagctt ccttgaccat
      301 ctctggggct caggtggaag atgaggctga ctattactgt gactcctggg acagcagcgg
      361 aacccaattc ggaggaggga cccggctgac cgtcctgggt cagcccaagg ctgccccctc
      421 ggtcactctc ttcccg
//
LOCUS       KCWK01004025             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:16102:4079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004025
VERSION     KCWK01004025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16102:4079"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69763.1"
                     /translation="DYYCQSYDSSLSGVLF"
     J_segment       414..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          155 c          128 g          113 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcagtggga gcaactccaa cattggatac tattatgtgc agtggtacca gcagcttcca
      241 gggacggccc ccaaactcct catctatgaa aataataagc gaccctctgg ggtttctgat
      301 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtttgagtgg tgtcttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004026             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:24507:7789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004026
VERSION     KCWK01004026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:24507:7789"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..392
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69764.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           88 a          157 c          114 g          115 t
ORIGIN      
        1 acatggggct gggatctcag gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaagc tgccccgact
      121 cagcctccct ctgtgtccgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgata ttgggtctta taatgctgtg tcttggtacc aacatcatcc aggcaaagcc
      241 ccccaactca taatttttga agtcaataag cggccctcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccaggc tgaggatgag
      361 gctgattatt actgctgctc atatgtaggc agcaacactt acatcttcga tgttgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004027             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:27968:10451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004027
VERSION     KCWK01004027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:27968:10451"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..237
                     /note="immunoglobulin light chain variable region"
     V_region        8..237
     V_segment       8..200
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <165..>209
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69765.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       201..237
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>275
                     /gene="IGLC"
BASE COUNT           58 a           86 c           69 g           62 t
ORIGIN      
        1 acatggggaa gccagggagt cccccccggt atcttctgag ttacgaatca gactcagata
       61 agggccaggg ctctggagtc cccagccgct tctctggatc caaaaatgct tcaacaaaca
      121 caggcatttt acacatctct gggctccagt ctgaggatga ggctgactat ttctgtgcca
      181 ttggacacag cagcggtcct tacatcttcg gtgctgggac ccggctcacc gtcctaggtc
      241 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004028             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:14273:16218
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004028
VERSION     KCWK01004028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14273:16218"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69766.1"
                     /translation="AYYCQVWDSDSDHYIF"
     J_segment       392..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           92 a          149 c          131 g           95 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaac taattttgtg cactggtacc agcagaagcc accgcaggcc cctatgcagg
      241 tcatctatgc tgataacaaa cggccctcag ggatccctga gagattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gagtcgaggc cggggatgag gctgcctatt
      361 actgtcaggt gtgggacagt gatagtgatc attacatctt cggtggtggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01004029             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:6885:8231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004029
VERSION     KCWK01004029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:6885:8231"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69767.1"
                     /translation="DYYCAVWDDRLTGYVF"
     J_segment       397..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          154 c          117 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagca atagtgtttc ctggtaccaa cagctcccag aaacggctcc caaactcctc
      241 atctattata atgatcggcg agcctcaggt gtccctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagtat gggatgatcg cctgaccggt tacgtattcg gtgttgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004030             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:15319:16163
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004030
VERSION     KCWK01004030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15319:16163"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69768.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          158 c          127 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtggtg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcactctg agtagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgtt ctgccagtcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgcaaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004031             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:6819:16799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004031
VERSION     KCWK01004031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6819:16799"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..289
                     /note="immunoglobulin light chain variable region"
     V_region        8..289
     V_segment       8..253
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69769.1"
                     /translation="VYYCCSYTTSSTYIF"
     J_segment       254..289
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           62 a          105 c           79 g           81 t
ORIGIN      
        1 acatgggcgg tcaccttctc ctgcactgga accaggactg acgttggtgg ttataactct
       61 gtctcctggt accaacagga ccccggcaaa gcccccaaac tcatcattta tggtgtcagt
      121 aatcggccct caggggtctc tgatcgcttc tctggctcca agtctggcag cacggcctcc
      181 ctgaccatct ctgggctcca ggctgaggac gaggctgttt attactgttg ttcatataca
      241 accagtagca cttacatctt cggtgctggg acccggctaa ccgtcctagg tcagcccaag
      301 gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01004032             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:25040:6537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004032
VERSION     KCWK01004032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25040:6537"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69770.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          163 c          111 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcctc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaagga tgcttcggcc aatgcaggcc ttttagtgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004033             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:16866:4539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004033
VERSION     KCWK01004033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16866:4539"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69771.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          141 c          136 g          102 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaggccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004034             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:12849:12706
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004034
VERSION     KCWK01004034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12849:12706"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69772.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          143 c          141 g           93 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttggaagtga agttgtgaac tggtaccagc agaagccagc gcaggcccct gtgctggtca
      241 tctatgctga tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg gggtgaggct gactattact
      361 gtcaggtgtg ggacatgcgt agtgatcaac cgctattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004035             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16571:3600
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004035
VERSION     KCWK01004035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16571:3600"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69773.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          145 c          141 g           93 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag cggaagccag cgcaggcccc tgtgctggtc
      241 atctatgctg ataccgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg ggggtgaggc tgactattac
      361 tgtcaggtgt gggacatgcg tagtgatcaa ccgctattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004036             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:20209:10129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004036
VERSION     KCWK01004036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20209:10129"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69774.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           96 a          161 c          111 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcaactcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 gttacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaaaatgc ttcaacaaac acaggcattt tacacatctc tgggctccag tctgaggatg
      361 aggctgacta tttctgtgcc attggacaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004037             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:8011:8985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004037
VERSION     KCWK01004037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8011:8985"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..242
                     /note="immunoglobulin light chain variable region"
     V_region        8..242
     V_segment       8..205
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <167..>214
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69775.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       206..242
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        243..>280
                     /gene="IGLC"
BASE COUNT           56 a           93 c           68 g           63 t
ORIGIN      
        1 acatgggtat gtctcctggt accaacaaca tccagacaca gcccccaaac tcgtgattta
       61 tgaagtcaat cagcggccct caggggtctc tgatcgcttc tctggctcca agtctggcaa
      121 cacggcctcc ctgaccatct ctggcctcca gcctgaggac gaggctgatt attactgcag
      181 ctcatatgca ggcagcgaca ctttcgtgtt attcggagga gggacccggc tgaccgtcct
      241 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004038             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:25073:19699
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004038
VERSION     KCWK01004038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:25073:19699"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69776.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           89 a          152 c          127 g          112 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg aggttattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccaaac tcctcatcta tgaaaatgat aaacgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctgattc ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agtagcttga gtgttgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004039             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:7456:9580
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004039
VERSION     KCWK01004039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7456:9580"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..265
                     /note="immunoglobulin light chain variable region"
     V_region        1..265
     V_segment       1..228
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69777.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       230..265
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           63 a           83 c           96 g           61 t
ORIGIN      
        1 acatgggggg gagacaacat tggaagtgaa gttgtgaact ggtaccagca gaagccaccg
       61 caggcccctg tgttggtcat gtatgctgat agcgagcggc cctcagggat ccctgagcga
      121 ttctctggct ccaaatcagg gaacacggcc accctgacca tcagcggggt cgaggccggg
      181 gatgaggctg actattactg tcaggtgtgg gacatgaata gtcatcatct gttattcgga
      241 ggggggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      301 ccg
//
LOCUS       KCWK01004040             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:5682:9307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004040
VERSION     KCWK01004040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5682:9307"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..435
                     /note="immunoglobulin light chain variable region"
     V_region        92..435
     V_segment       92..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69778.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          162 c          112 g          112 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccctggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc tgcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatcg gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttcct
      241 tctactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt gctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004041             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:4604:19068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004041
VERSION     KCWK01004041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:4604:19068"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69779.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       414..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          164 c          123 g          108 t
ORIGIN      
        1 tacatggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcactgac
      181 ctcagtgttg gtggtaaaaa catgtactgg taccagcaga agccaggaag cgctcccagg
      241 ttattgctgt attaccactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgccaa cacgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004042             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:11997:15226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004042
VERSION     KCWK01004042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11997:15226"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    67..405
                     /note="immunoglobulin light chain variable region"
     V_region        67..405
     V_segment       67..368
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69780.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       369..405
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>443
                     /gene="IGLC"
BASE COUNT           86 a          144 c          114 g           99 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc
      121 cctgcaccct gagcagtgac ctcagtgttg gtaataaaaa catgtactgg taccaacaga
      181 agccagggag cgctcccagg ttattcctgt actactactc cgactcagac aagcagctgg
      241 gacctggggt ccccaatcga gtctctggct ccaaggagac ctcaactaac acagcgtttt
      301 tgctcatctc tgggctccag cctgaggacg aggccgatta ttactgtcag gtgtttgaca
      361 gtagtgctgt gttattcgga ggagggaccc gactgaccgt cctaggtcag cccaaggctg
      421 ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004043             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11482:10459
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004043
VERSION     KCWK01004043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11482:10459"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69781.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          162 c          115 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctctgcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatataa atcagactca gataacgacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcctcagcg aacacgggac ttttgcgcat ctctgggctc cagtctgagg
      361 atgaggctga ctactactgt gccattggac acagcagcgg tgattacatc ttcggtgctg
      421 ggacccgcct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004044             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:19554:18836
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004044
VERSION     KCWK01004044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19554:18836"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69782.1"
                     /translation="DYYCSSYAGSNTFVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          159 c          127 g          103 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gccgcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggcggttata actatgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcatg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct gacgacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat atgcaggcag caacactttc gtgttgttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004045             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:27631:7812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004045
VERSION     KCWK01004045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:27631:7812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69783.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gttcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004046             354 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:25320:4959
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004046
VERSION     KCWK01004046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 354)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:25320:4959"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..316
                     /note="immunoglobulin light chain variable region"
     V_region        8..316
     V_segment       8..276
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <244..>288
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69784.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       283..316
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        317..>354
                     /gene="IGLC"
BASE COUNT           77 a          104 c           91 g           82 t
ORIGIN      
        1 acatgggctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat cactgttgct
       61 ggctaccata tatattggta ccagcagaag ccagggagtc ccccccggta tcttctgagg
      121 tacaaatcag actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      181 aaagatgctt cagcgaacac agggatttta cgcatatctg gactccagtc tgaggatgag
      241 gctgactatt actgtgccat tggacacagc agcggtgatt atatcttcgg tgctgggacc
      301 cgtctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004047             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:17738:12917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004047
VERSION     KCWK01004047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17738:12917"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..434
                     /note="immunoglobulin light chain variable region"
     V_region        106..434
     V_segment       106..400
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69785.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       401..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>474
                     /gene="IGLC"
BASE COUNT           82 a          165 c          113 g          114 t
ORIGIN      
        1 acatggggct ggggtctcag aaggcagcgc tctcaggacg tctccaccat ggcctggact
       61 ctgctcctcg tcaccctcct cactcaaggc acaggatcct gggctcagtc tgccccgact
      121 cagcctccct ctgtgtctgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 accagtgacg ttggtggttc taactctgtc tcctggtacc aacaacaccc aggcaaagcc
      241 cccaaactca tgatttttgg tgtcaataat cggccctctg gggtctctga ccgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccagtc tgaggacgag
      361 gctgattatt actgttgttc acattcaacc agtagcactt acgtcttcgg tcctgggacc
      421 cggctcaccg tcctgggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004048             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:17083:7086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004048
VERSION     KCWK01004048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17083:7086"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..443
                     /note="immunoglobulin light chain variable region"
     V_region        115..443
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69786.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       412..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>483
                     /gene="IGLC"
BASE COUNT           88 a          161 c          126 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct cccagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gacgatagcc tgcgcggcta tatcttcggt
      421 gctgggaccc ggctcaccgt cctgggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004049             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:24928:7748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004049
VERSION     KCWK01004049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24928:7748"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69787.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       393..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT          106 a          136 c          122 g          101 t
ORIGIN      
        1 acatgggggt gtggttctag gaggaagagc tctgggtgtc tcaccatgac ctggaccact
       61 gttctgctcc cctttctcac tctctgcaca ggctctgagg cctcctatga gctgacacag
      121 ccaccctcag tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagaaata
      181 ctggcaaaaa aatatactca gtggttccag cagcagccag gccaggcccc tttcctggtg
      241 atatataaag acagtgagag gccctcaggg atccctgagc gattctctag ctccagttca
      301 gggacaacaa ttaccttgac catcagtggg gcccaggcag aagatgaggc tgactattac
      361 tgtcaatcag tagacagcag tggaaatctt ccgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004050             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:24029:4033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004050
VERSION     KCWK01004050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:24029:4033"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69788.1"
                     /translation="YYYCSSYAGSHTYIF"
     J_segment       398..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           78 a          164 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctcagggg gcagcgctct caggacgtct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca gggtcctggg ctcaggctgc cctgactcag
      121 cctccctctg tgtctgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgacatcg gtggttataa ctatgtctcc tggttccagc agcaccccgg caaagccccc
      241 aaactcatga tttatgatgt cactcagcgg ccctcagggg tctctgatcg cttctctggc
      301 tccaaatctg gctacacggc ctccctgacc atctctgggc tccaggctgc ggatgaggct
      361 tattattact gcagctcata tgcgggcagc cacacttaca tcttcggtac tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01004051             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:7398:9007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004051
VERSION     KCWK01004051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7398:9007"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..403
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69789.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       407..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           94 a          156 c          123 g          109 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata atgtgtcctg gtaccagcac ctcccaggaa
      241 cagctcccaa actcctcatc tattataatg atcaacgagg ctcaggtgtc tctggccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcgtggg atgatagcct gagtagttac atcttcgctg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01004052             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:22662:23302
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004052
VERSION     KCWK01004052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:22662:23302"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..402
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69790.1"
                     /translation="DYYCCSYRNGNTWLF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           85 a          156 c          125 g          110 t
ORIGIN      
        1 acatgggggg ctggggtctc aggaggcagc gctctcggga cgtctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag tctgccctga
      121 ctcagcctcc ctcagtgtcc aagtctcttg gacagtcggt caccatctcc tgtattggaa
      181 ccagcagtga cattggtggt tatgatggcg tctcctggta ccagcaacac tcagagacag
      241 cccccacact cctgatttat gatgtcacta agcggccctc aggggtctcg gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tcaccatctc tgggctccag actgaggacg
      361 aggctgatta ttactgttgt tcatatagga atggaaacac ttggctattc ggcggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004053             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:25068:7931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004053
VERSION     KCWK01004053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:25068:7931"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69791.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          162 c          124 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatcgct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004054             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16694:9855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004054
VERSION     KCWK01004054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16694:9855"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..422
                     /note="immunoglobulin light chain variable region"
     V_region        98..422
     V_segment       98..379
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69792.1"
                     /translation="DYYCQVWDSSSDHWIF"
     J_segment       385..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          147 c          132 g           89 t
ORIGIN      
        1 acatggggtc tcaggaggca gcattgacgg tgcctcagcc atggcctgga cccttctcct
       61 cctcggcctc ctcgctcact gcacagactc tgcgacctcc tatgagctga ctcagccacc
      121 ctcggtgtca gcggcctcag gacagacggc caggatcacc tgtgggggag acaacattgg
      181 aagtaaatat gtgcactggt accagcagag gccaccgcag gcccctgtgc aagtcatcta
      241 tactgatagc agacggccct cagggatccc tgagcgattc tctggctcca actcagggaa
      301 caccgccacc ctgaccatca gcgcggtcga ggccggggat gaggctgact attactgtca
      361 ggtgtgggac agtagtagtg atcattggat attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004055             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:24653:17962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004055
VERSION     KCWK01004055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24653:17962"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69793.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       405..439
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           90 a          160 c          114 g          113 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgacccagcc aacctccctc
      121 tcagcatctc cgggagcatc agtccgactc agctgcacct tgagcagtgg catcaatgtt
      181 ggttcttaca ccatattctg gtaccagcag aagccaggga gtcctccccg gttccttctg
      241 tactactact cagactcaaa taatcaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcagccaa tgcagggctt ttactgatct ctgggctcca gtctgaagat
      361 gaggctgact attactgtgc catgtggcac agcagcgctt atgccttatt cggaggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004056             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:14367:20863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004056
VERSION     KCWK01004056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14367:20863"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..295
                     /note="immunoglobulin light chain variable region"
     V_region        8..295
     V_segment       8..258
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <220..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69794.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       259..295
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        296..>333
                     /gene="IGLC"
BASE COUNT           65 a          104 c           86 g           78 t
ORIGIN      
        1 acatggggga agagtgtctc catctcctgt tctggaagca gctccaacat cggaagtcat
       61 agtgtctcct ggtaccagca gctcccagga acagctccca aactcctcat ctattatagt
      121 gatcaacgag cctcaggtgt ctctgaccga ttctctggct ctcagtctgg cacgtcagcc
      181 tccctggcca tcagtgggct ccagaccgag gatgaggctg attattactg cgcagcatgg
      241 gatgatagcc tgagcggtta catcttcggt gctgggaccc ggctcgccgt cctaggtcag
      301 cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004057             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:12585:17562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004057
VERSION     KCWK01004057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12585:17562"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69795.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           92 a          160 c          117 g          111 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgttgcct accacataca ctggtaccag cagaagccag ggagtccccc ccggtatctt
      241 ctgaggtaca aatcagactc agataagggc cagggcgctg gagtccccag ccgcttctct
      301 ggatccaata atgtttcagc gaacacaggg attttacgca tctctggcct ccagtctgag
      361 gatgaggctg actattactg tgccattggg cacagcagcg gtccttacat cttcggtgct
      421 gggacccgtc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004058             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:20649:16632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004058
VERSION     KCWK01004058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20649:16632"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69796.1"
                     /translation="VYYCQVWDSSSEWVF"
     J_segment       387..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           90 a          144 c          136 g           91 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgag ctgactcagc
      121 caccctcagt gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa aactgtgcac tggtaccaac agaaggcagc acaggcccct atgctggtca
      241 tctttgctga tagcaaacgg ccctcaggga tccctgaccg attctctggc tccaactcag
      301 ggaacaccgg caccctgacc atcagcgggg tcgaggccgg ggatgaggct gtctattact
      361 gtcaggtgtg ggacagtagt agtgagtggg ttttcggcgg agggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004059             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:17453:9970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004059
VERSION     KCWK01004059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17453:9970"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69797.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           82 a          161 c          122 g          103 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtggccac
      181 tacagctaca ccatcgcatg gcatcagcag cagcaaggga aggcccctcg gttcttgatg
      241 tggcttaaga gtgatggcag ccacaccaag ggggacgggg tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatattggc atttgggtat tcggcggagg gactcggcta
      421 atcgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004060             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:9094:3567
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004060
VERSION     KCWK01004060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9094:3567"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69798.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          163 c          123 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagtagtgac
      181 ctcagtgttg gtagtaaaaa catctactgg taccagctga agccagggag cgctcccagg
      241 tcattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtctatgaca gtagtgctaa tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004061             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:7428:7863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004061
VERSION     KCWK01004061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7428:7863"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69799.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          157 c          119 g          108 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcggcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccaac agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtcaccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccgact caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004062             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18297:10302
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004062
VERSION     KCWK01004062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18297:10302"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..441
                     /note="immunoglobulin light chain variable region"
     V_region        111..441
     V_segment       111..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69800.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       405..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          154 c          125 g          110 t
ORIGIN      
        1 acatggggct tcagctgtgg gcacaggagg cagcactcag gacagtctcc agcatggcct
       61 ggtctcctct cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc
      121 tgacgcagcc gccctcagtg tctggggcgc ccgggcagag ggtcaccatc tcctgcactg
      181 ggagcagctc caacattgga gattattatg tgcagtggta ccagcacctt ccaggaacgg
      241 cccccagact cctcatctat gaaaataata agcgaccctc aggggtttct gatcgattct
      301 ctggctccca gtctggaacc tcagcctccc tgaccatcac tggactccag tctgaggatg
      361 aggctgatta ttactgccag tcctatgaca gcagtttgat tgctgtgtta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004063             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17469:4549
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004063
VERSION     KCWK01004063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17469:4549"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69801.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          156 c          123 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgttgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctactataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagac tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004064             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:24844:16124
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004064
VERSION     KCWK01004064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24844:16124"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69802.1"
                     /translation="DYYCASWDDSLRGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          155 c          125 g          110 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaac agtgtcgcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatgatga tcaacgagcc tcgggtgtct ctgaccgatt
      301 ctctggctcc aggtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cttcatggga tgatagcctg agaggttaca tcttcggtga
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01004065             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:11052:4248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004065
VERSION     KCWK01004065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11052:4248"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69803.1"
                     /translation="DYYCYSYRTGNSWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          156 c          125 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccaa cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattat tgttactcat ataggactgg aaacagttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004066             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:14055:14602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004066
VERSION     KCWK01004066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14055:14602"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69804.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       398..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          159 c          122 g          101 t
ORIGIN      
        1 acatggggga gcagagccct gaggagtctg caccatggcc tggaccccaa tcctcctcct
       61 cctcctcact ctcctccttc actgcacagg gtctctctcc cagcctgtgc tgactcagtc
      121 gccctctgtc tctgcctccc tgggagcctc ggtcaaactc acctgtactt tgaacagtgg
      181 gcacagcagc tacaccatcg catggcatca gcagcagcaa gggaaggccc cccggtactt
      241 gatgtggctt aaaagtgaag gcagccatag caagggggac gggatccctg atcgcttctc
      301 aggctccagc tccggggctg agcgctacct caccatctcc aacctccagt ctgaggatga
      361 ggctgattat tactgtcaga cctgggatac tgacattgtg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004067             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:22568:4554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004067
VERSION     KCWK01004067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22568:4554"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..275
                     /note="immunoglobulin light chain variable region"
     V_region        8..275
     V_segment       8..235
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <203..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69805.1"
                     /translation="VYYCQVWDSSSEWVF"
     J_segment       239..275
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>313
                     /gene="IGLC"
BASE COUNT           67 a           89 c           95 g           62 t
ORIGIN      
        1 acatgggagg atcacctgtg ggggagacaa cattggaact aaaactgtgc actggtacca
       61 acagaaggca gcacaggccc ctatgctggt catctttgct gatagcaaac ggccctcagg
      121 gatccctgac cgattctctg gctccaactc agggaacacc ggcaccctga ccatcagcgg
      181 ggtcgaggcc ggggatgagg ctgtctatta ctgtcaggtg tgggacagta gtagtgagtg
      241 ggttttcggc ggagggaccc ggctaaccgt cctaggtcag cccaaggctg ccccctcggt
      301 cactctcttc ccg
//
LOCUS       KCWK01004068             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:24503:18010
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004068
VERSION     KCWK01004068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:24503:18010"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69806.1"
                     /translation="AYYCQVWDSDSDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          149 c          130 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaagccag cgcaggcccc tatgcaggtc
      241 atctatgctg ataacaaacg gccctcaggg atccctgaga gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctattac
      361 tgtcaggtgt gggacagtga tagtgatcat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004069             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:11899:14108
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004069
VERSION     KCWK01004069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11899:14108"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69807.1"
                     /translation="DYYCSSYAGSNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          156 c          118 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcactaat attggatatt ataatgctgt gtcttggtac caacaccatc caggcaaagc
      241 ccccagactc atgatttatg acgtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacaat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004070             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:4440:15587
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004070
VERSION     KCWK01004070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4440:15587"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69808.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          147 c          128 g           98 t
ORIGIN      
        1 acatgggggg gccttaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtacact ggtaccagca caagccaccg caggcccctg ttctgctcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttgttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004071             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:13578:20324
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004071
VERSION     KCWK01004071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13578:20324"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    68..398
                     /note="immunoglobulin light chain variable region"
     V_region        68..398
     V_segment       68..362
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <326..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69809.1"
                     /translation="DYYCCYHTTSGSYIF"
     J_segment       363..398
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>436
                     /gene="IGLC"
BASE COUNT           77 a          152 c          104 g          103 t
ORIGIN      
        1 acatgggacc atggcctgga ctctgctcct cgtcaccctc ctcactcaag gcacaggatc
       61 ctgggctcag tctgccccga ctcagcctcc ctctgtgtct gggtctcctg gacagtcggt
      121 caccatctct tgcactggaa ccagcagtga cgctgctggt tatacctctg tctcctggta
      181 ccaacagccc ccaggcaaag cccccaaact catgatttat ggtgtcagtc atcggccctc
      241 aggggtctct gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc
      301 tgggctccag gctgaggacg aggctgatta ttactgttgt taccacacaa ccagtggcag
      361 ttacatcttc gatggtggga cccggctcac cgtcctaggt cagcccaagg cttcccccac
      421 ggtcactctg ttcccg
//
LOCUS       KCWK01004072             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12120:18579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004072
VERSION     KCWK01004072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12120:18579"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69810.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           82 a          165 c          114 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 caccagtgac gttggtggtt ctaactctgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaactc atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagt ctgaggacga
      361 ggctgattat tactgttgtt cacattcaac cagtagcact tacgtcttcg gtcctgggac
      421 ccggctcacc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004073             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:9017:11555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004073
VERSION     KCWK01004073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9017:11555"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..446
                     /note="immunoglobulin light chain variable region"
     V_region        98..446
     V_segment       98..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69811.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       412..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           90 a          164 c          122 g          108 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagcctcc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcactgacct
      181 cagtgttggt ggtaaaaaca tgtactggta ccagcagaag ccaggaagcg ctcccaggtt
      241 attgctgtat taccactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtatgacagt agtgccaaca cgttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01004074             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:19750:10689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004074
VERSION     KCWK01004074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19750:10689"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69812.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           87 a          143 c          135 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcgctg tcagtgtccc caggacagac ggccaggatc acctgtggag gcgacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaggccaccg caggcccctg tgctggtcat
      241 ctgtgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004075             360 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:13182:23931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004075
VERSION     KCWK01004075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 360)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 360)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..360
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13182:23931"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..322
                     /note="immunoglobulin light chain variable region"
     V_region        7..322
     V_segment       7..258
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <232..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69813.1"
                     /translation="DYYCQSYDSQSYDTSLSVRVF"
     J_segment       287..322
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>360
                     /gene="IGLC"
BASE COUNT           67 a          113 c           97 g           83 t
ORIGIN      
        1 acatgggggg cgcccgggca gagggtcacc atctcctgca ctgggagcag ctccaacatc
       61 ggggcgggtt attatgtgcg gtggtaccag cagcttccag gaacggcccc ccaactcctc
      121 atctatgata cttataagcg accctcaggg gtttctgatc gaatctctgg ctccaagtct
      181 ggtacctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      241 tgccagtcct atgacagcca gtcctatgac accagtttga gtgttcgggt tttcggcggt
      301 gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004076             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:17513:20201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004076
VERSION     KCWK01004076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17513:20201"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69814.1"
                     /translation="HYYCCSHSTSSTYVF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           83 a          166 c          112 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctactcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 caccagtgac gttggtggtt ctaactctgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaactc atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagt ctgaggacga
      361 ggctcattat tactgttgtt cacattcaac cagtagcact tacgtcttcg gtcctgggac
      421 ccggctcacc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004077             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:19870:8629
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004077
VERSION     KCWK01004077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19870:8629"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..415
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69815.1"
                     /translation="DYYCSAWDSSLTGGFF"
     J_segment       417..454
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           99 a          156 c          129 g          108 t
ORIGIN      
        1 acatgggggg gggaagctca gcttcagctg tggctagaga agacaggact caggacaatc
       61 tccagcatgg cctgcttccc tctcatcctc accgtcctca ctcactgtgc aggatcctgg
      121 gcccagtctg tgctgactca accaccctca gcgtctgggg cccccgggca gagtgtcacc
      181 atctcctgtt ctggaagcag ctccaacatc ggaagtaatt atgtatactg gtaccagcag
      241 ttctcaggga aggcccccaa actcctcatc cataataata atcagcgacc ctcaggggtc
      301 cctgatcgat tctctggctc caagtctggc acgtcagcct ccctggacat cagtgggctc
      361 cagtccgagg atgaggctga ttattactgc tcagcatggg atagcagtct gaccggtggc
      421 tttttcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCWK01004078             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:9212:18578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004078
VERSION     KCWK01004078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9212:18578"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69816.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          164 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc accaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004079             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:14594:14510
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004079
VERSION     KCWK01004079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14594:14510"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..284
                     /note="immunoglobulin light chain variable region"
     V_region        91..284
     V_segment       91..247
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <209..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69817.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       250..284
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>322
                     /gene="IGLC"
BASE COUNT           56 a          105 c           88 g           73 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcctcatc ttttataatg atcggcgagc
      121 ctcaggtgtc tctgaccgat tctctggctc caagtctggc acgtcagcct ccctggccat
      181 cagtgggctc cagaccgagg atgaggctga ttattactgc gcagcatggg atgatagcct
      241 gagcggtccg gtattcggcg gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc
      301 cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004080             305 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:17437:5734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004080
VERSION     KCWK01004080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 305)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17437:5734"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    67..267
                     /note="immunoglobulin light chain variable region"
     V_region        67..267
     V_segment       67..228
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <192..>239
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69818.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       233..267
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        268..>305
                     /gene="IGLC"
BASE COUNT           67 a           84 c           85 g           69 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttcctggtg atatataaag acagtgagag gccctcaggg atccctgagc
      121 gattctctag ctccagttca gggacaacaa tgaccttgac catcagtggg gcccaggcag
      181 aagatgaggc tgactattac tgtcaatcag tagacagcag tggaaatctt ccgttattcg
      241 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      301 tcccg
//
LOCUS       KCWK01004081             372 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:12209:12760
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004081
VERSION     KCWK01004081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 372)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12209:12760"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    145..334
                     /note="immunoglobulin light chain variable region"
     V_region        145..334
     V_segment       145..297
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>306
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69819.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       300..334
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        335..>372
                     /gene="IGLC"
BASE COUNT           66 a          130 c           92 g           84 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcaaggaagc accagggctc tggagtcccc
      181 agccgcttct ctggatccaa agatgcttca gccaatgcag ggctgttact gatctctggg
      241 ctccagtctg aagatgaggc tgactattac tgtgccctat ggcacagcag cgcttcttgc
      301 atcttcggtg gtgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      361 actctgttcc cg
//
LOCUS       KCWK01004082             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:4569:7922
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004082
VERSION     KCWK01004082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:4569:7922"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69820.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          152 c          122 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctcggg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004083             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:7494:16483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004083
VERSION     KCWK01004083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7494:16483"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..249
                     /note="immunoglobulin light chain variable region"
     V_region        7..249
     V_segment       7..212
                     /gene="IGLV5-107"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <174..>221
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69821.1"
                     /translation="DYYCCTWHGSSKTQIF"
     J_segment       217..249
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        250..>287
                     /gene="IGLC"
BASE COUNT           61 a           91 c           71 g           64 t
ORIGIN      
        1 acatggggta ccaacaaaag ccagggagcc ctccccggta tctcctgtac taccactcag
       61 actcagataa ccaccgaggc tctggagttc ccagccgctt ctctggatcc aatgatgcat
      121 cagccaatgc agggattctc tttatctctg ggctccagcc tgaggatgag gctgactatt
      181 actgttgtac atggcatggc agctctaaga ctcagatatt cggcggaggg acccggctga
      241 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004084             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:19436:11086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004084
VERSION     KCWK01004084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19436:11086"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69822.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           96 a          153 c          112 g          116 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcg cagcctgtgc tgactcagcc aacctccctc
      121 tcagcatctc ctggagcatc agccagactc acctgcacct tgaacagtgg catcagtgtt
      181 gctaattaca ggatattctg gtaccaccag aagccaggga gtcctccccg gtatcttctg
      241 aactaccaca cagactcaga tattcatcag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcggccaa tgcagggatt ttactcatct ctggactcca gtctgaggat
      361 gaggctgact attactgtat gatttggcac aacaatgctt attgggtttt cggcggaggg
      421 acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004085             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:23370:9637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004085
VERSION     KCWK01004085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23370:9637"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    60..408
                     /note="immunoglobulin light chain variable region"
     V_region        60..408
     V_segment       60..371
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69823.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       374..408
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           83 a          152 c          107 g          104 t
ORIGIN      
        1 acatgggctg gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc
       61 agcctgtgct gacccagcca acctccctct cagcatctcc gggagcatca gccagactca
      121 actgcacctt gagcagtggc gtcaatgtgg gtagttacag catattctgg taccagcaga
      181 agccagggag tcctccccgg taccttctgt actaccagtc agactcaagg aagcaccagg
      241 gctctggagt ccccagccgc ttctctggat ccaaagatgc ttcagccaat gcagggctgt
      301 tactgatctc tgggctccag tctgaagatg aggctgacta ttactgtgcc ctatggcaca
      361 gcagcgcttc ttgcatcttc ggtggtggga cccggctcac cgtcctaggt cagcccaagg
      421 cttcccccat ggtcactctg ttcccg
//
LOCUS       KCWK01004086             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:14247:2782
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004086
VERSION     KCWK01004086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14247:2782"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69824.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          152 c          123 g          113 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggttcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt ataacgctgt gtcttggtac caacagcatc caggcaaagc
      241 ccccaaactc ataatttttg acgtcattaa gcggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccggg ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagaaataat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004087             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:13034:11878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004087
VERSION     KCWK01004087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13034:11878"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..249
                     /note="immunoglobulin light chain variable region"
     V_region        1..249
     V_segment       1..212
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <177..>221
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69825.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       213..249
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        250..>287
                     /gene="IGLC"
BASE COUNT           61 a           86 c           77 g           63 t
ORIGIN      
        1 acatgggctg gtaccagcag aagccaggga gcgctcccag gtcattccta tactactact
       61 ccgactcaga caagcagctg ggacctgggg tccccaatcg agtctctggc tccaaggaga
      121 cctcaagtaa cacagcgttt ttgctcatct ctggactcca gcctgaggac gaggccgatt
      181 attactgtca ggtgtatgac agtagtgcta atgtgttatt cggaggaggg acccggctga
      241 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004088             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:22745:14579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004088
VERSION     KCWK01004088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22745:14579"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69826.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       403..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           83 a          162 c          128 g           98 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtggt gactcagtcg
      121 tcctctgcct ctgcctccct gggagcctcg gtcaagctcg cctgcactct gagcggtggg
      181 cacagcgact acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggtatttg
      241 atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctga tcgcttctcc
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggagact ggcattcagg tgttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004089             356 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:12289:20279
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004089
VERSION     KCWK01004089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 356)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 356)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..356
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12289:20279"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..318
                     /note="immunoglobulin light chain variable region"
     V_region        8..318
     V_segment       8..282
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <246..>290
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69827.1"
                     /translation="YYYCSSYAGSHTYIF"
     J_segment       283..318
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        319..>356
                     /gene="IGLC"
BASE COUNT           64 a          120 c           85 g           87 t
ORIGIN      
        1 acatgggtcc ctctgtgtct gggtctcctg gacagtcggt caccatctcc tgcactggaa
       61 ccagcagtga catcggtggt tataactatg tctcctggtt ccagcagcac cccggcaaag
      121 cccccaaact catgatttat gatgtcactc agcggccctc aggggtctct gatcgcttct
      181 ctggctccaa atctggctac acggcctccc tgaccatctc tgggctccag gctgcggatg
      241 aggcttatta ttactgcagc tcatatgcgg gcagccacac ttacatcttc ggtactggga
      301 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004090             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:14507:12421
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004090
VERSION     KCWK01004090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14507:12421"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69828.1"
                     /translation="AYYCQVWDSDSDHYIF"
     J_segment       388..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          148 c          130 g           93 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctatgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaat tttgtgcact ggtaccagca gaagccaccg caggccccta tgcaggtcat
      241 ctatgctgat aacaaacggc cctcagggat ccctgagaga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggagt cgaggccggg gatgaggctg cctattactg
      361 tcaggtgtgg gacagtgata gtgatcatta catcttcggt ggtgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004091             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:19852:15099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004091
VERSION     KCWK01004091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19852:15099"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69829.1"
                     /translation="HYYCCSHSTSSTYVF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           82 a          166 c          113 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 caccagtgac gttggtggtt ctaactctgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaactc atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagt ctgaggacga
      361 ggctcattat tactgttgtt cacattcaac cagtagcact tacgtcttcg gtcctgggac
      421 ccggctcacc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004092             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:5905:10494
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004092
VERSION     KCWK01004092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:5905:10494"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69830.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          163 c          109 g          114 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca cctttagcag tggcatcaat
      181 gttggtagtt acagcatatt ctggtaccaa cagaagccag ggagtcctcc ccggtacctt
      241 ctctactact actcagactc aagtaaacac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatgcaggc cttttactga tctctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccatatgg cacagcagcg cttcttactt cttcggtact
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004093             372 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:11545:21241
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004093
VERSION     KCWK01004093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 372)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11545:21241"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..334
                     /note="immunoglobulin light chain variable region"
     V_region        13..334
     V_segment       13..298
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>306
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69831.1"
                     /translation="DYYCQVWDSSSEWVF"
     J_segment       299..334
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        335..>372
                     /gene="IGLC"
BASE COUNT           80 a          110 c          111 g           71 t
ORIGIN      
        1 acatgggcga cctcctatga attgactcag gcaccctcag tgtcagcggc ctcaggacag
       61 acggccagga tcacctgtgg gggagacaac attggaagta aaactgtgca ctggtaccaa
      121 cagaaggcag cgcaggcccc tgtgctggtc atctttgctg atagcaaacg gccctcaggg
      181 atccctgacc gattctctgg ctccaactca gggaacaccg ccaccctgac catcagcggg
      241 gtcgaggccg gggatgaggc tgactattac tgtcaggtgt gggacagtag tagtgaatgg
      301 gttttcggcg gagggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      361 actctcttcc cg
//
LOCUS       KCWK01004094             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:24174:11197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004094
VERSION     KCWK01004094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24174:11197"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..427
                     /note="immunoglobulin light chain variable region"
     V_region        94..427
     V_segment       94..390
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69832.1"
                     /translation="EYYCQTWDIGIWVF"
     J_segment       391..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           85 a          159 c          119 g          102 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 actctcctcc ttcactgcac agggtctctc tcccagcctg tgctgactca gtcgccctct
      121 gcctctgcct ccctgggagc ctcggtcaag ctcacctgca ctctgagcag tgggcactac
      181 agctatacca tcgcatggca tcaacaatat caagggaagg cccctcggtt cttgatgtgg
      241 cttaaaagtg atggcagcca caccaagggg gacgggatcc ctgatcgctt ctcaggctcc
      301 agctccgggg ctgagcgcta cctctccatc tccaacctcc agtctgagga tgaggctgag
      361 tattactgtc agacctggga cattggcatt tgggtattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004095             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:18150:13328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004095
VERSION     KCWK01004095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18150:13328"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69833.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       414..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           92 a          159 c          129 g          108 t
ORIGIN      
        1 acatggggga agcgcagctt cagctgtggg tacagaaggc aggactcagg acaatctcca
       61 gcatggcctg gttccctctc gtcctcaccc tcctcactca ctgtccaggg tcctgggccc
      121 agtctgtgct gactcagcct ccctcagcgt ctgaggccgc caggaacagt gtcgccatct
      181 cctgttctgg aggcagctcc aacatcggca gtcatagtgt atcctggtac cagcagctcc
      241 caggaacagc tcccaaactc ctcatctatt atgatgatca acgagcctca ggtgtctctg
      301 gccgattctc tggctccagg tctggcacgt cagcctccct ggccatcagt gggctccaga
      361 ccgaggatga ggctgattat tactgcgcag catgggatga tagcctgaga ggttacatct
      421 tcggtgatgg gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCWK01004096             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:26283:11756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004096
VERSION     KCWK01004096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:26283:11756"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..289
                     /note="immunoglobulin light chain variable region"
     V_region        8..289
     V_segment       8..252
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <220..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69834.1"
                     /translation="DYYCAIGHSSGYIF"
     J_segment       253..289
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           68 a           99 c           88 g           72 t
ORIGIN      
        1 acatggggca ccttcagtgg tggcatcaat gttgctggct accacacaca ctggtaccag
       61 cagaagccag ggagtcctcc ccggtatctt ctgagataca aatcagactc agataagggc
      121 cagggctctg gagtccccag ccgcttctct ggatccagag atgcttcagc gaacacaggg
      181 attttacgca tctctgggct ccagtctgag gatgaggctg actattactg tgccattggg
      241 cacagcagcg gttacatctt cggtgctggg acccggctca ccgtcctagg tcagcccaag
      301 gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01004097             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:12109:7048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004097
VERSION     KCWK01004097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12109:7048"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..296
                     /note="immunoglobulin light chain variable region"
     V_region        7..296
     V_segment       7..259
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <227..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69835.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       263..296
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>334
                     /gene="IGLC"
BASE COUNT           68 a          109 c           85 g           72 t
ORIGIN      
        1 acatgggggg cagacggtca ccatctcctg cacccgcagc agtggcagca ttgacaacgg
       61 ctttgtgtac tggtaccagc agcggccggg cagcgctccc accactgtga tttacaaaga
      121 taaccaaaga ccctctgggg tccctgatcg gttctctggc tccatcgaca gctcctccaa
      181 ctctgcctcc ctcaccatct ctggactgaa atctgaggac gaggctgact attactgtca
      241 gtcttatgac agcagcagtg tattattcgg aggagggacc cggctgaccg tcctaggtca
      301 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004098             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:4052:15891
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004098
VERSION     KCWK01004098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:4052:15891"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..388
                     /note="immunoglobulin light chain variable region"
     V_region        64..388
     V_segment       64..351
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <313..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69836.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       355..388
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           82 a          128 c          123 g           93 t
ORIGIN      
        1 acatgggtgg cctggacttt tctcctcctc ggcctccttg cttactgcac aggctctgcg
       61 gcctcctatg atctgactca ggcaccctcg atttcagtgt cccccggaca gacggccagg
      121 atcacctgtg ggggagacaa cattggaagt gaagttgtga actggtacca gcagaagcca
      181 ccgcaggccc ctgtgttggt catgtatgct gatagcgagc ggccctcagg gatccctgag
      241 cgattctctg gctccaaatc agggaacacg gccaccctga ccatcagcgg ggtcgaggcc
      301 ggggatgagg ctgactatta ctgtcaggtg tgggacatga atagtcatca tctattattc
      361 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      421 ttcccg
//
LOCUS       KCWK01004099             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:11947:18420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004099
VERSION     KCWK01004099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:11947:18420"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69837.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          161 c          115 g          108 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctctgcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcagactca gaaaaggacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcctcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctactactgt gccattgggc acagcagcgg tgattacatt ttcgctgctg
      421 ggacccgcct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004100             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11582:9827
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004100
VERSION     KCWK01004100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11582:9827"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69838.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       387..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>461
                     /gene="IGLC"
BASE COUNT           94 a          143 c          125 g           99 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc catcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaagat cacctgctct ggagatgcac
      181 tgccaaaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtgttgatca
      241 tcgatgagga caccaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttactcagc agacagcagt ggttatggct tattcggagg agggacccgg ctgaccgtcc
      421 tacgtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004101             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:16271:13505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004101
VERSION     KCWK01004101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16271:13505"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..445
                     /note="immunoglobulin light chain variable region"
     V_region        120..445
     V_segment       120..410
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69839.1"
                     /translation="DYYCQSADGNYRVF"
     J_segment       411..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>484
                     /gene="IGLC"
BASE COUNT           86 a          167 c          126 g          105 t
ORIGIN      
        1 acatgggggg ctgcttcctg gctgtgactc agaaagcaga gcctggggcg tctccaccat
       61 ggcctgggct ccactcctcc tcaccctcct cgctcactgc acagggtctt gggctgaact
      121 tgtgttcact cagccccatt ctgtgtcggg gtctccgggg cagacggtca ccatctcctg
      181 cacccgcagc attggcaaca ttgacagtga atatgtgcag tggtaccagc agcgcccggg
      241 cagtgccccc accacactga tttacaaaga tagtcaaaga ccctctgggg tccctgaccg
      301 gttctctggc tccatcgaca gctcctccaa ctctgcctcc ctcgccatct ctgggctaca
      361 gtctgaggac gaggctgact actactgtca gtctgctgat ggcaactaca gggtcttcgg
      421 cggagggacc cggctaaccg tcctaagtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01004102             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:22693:16710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004102
VERSION     KCWK01004102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22693:16710"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69840.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          141 c          132 g           94 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgaat tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa actgtgcact ggtaccaaca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgat agtagacggc cctcagggat ccctgagcga ttctctggct ccaattcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004103             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:21719:14406
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004103
VERSION     KCWK01004103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21719:14406"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69841.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          165 c          122 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccgactgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004104             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:9709:6948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004104
VERSION     KCWK01004104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:9709:6948"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69842.1"
                     /translation="DYYCGIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          157 c          117 g          108 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcacgggt ggcatcaatg
      181 ttgctgacta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt ggcattgggc acagcagcgg tgattacatc ttcgctgatg
      421 ggacccgact caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004105             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:22226:23622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004105
VERSION     KCWK01004105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22226:23622"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69843.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          151 c          122 g          115 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggttcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt ataacgctgt gtcttggtac caacagcatc caggcaaagc
      241 ccccaaactc ataatttttg acgtcattaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccggg ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagaaataat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgtcccctcg gtcactctct tcccg
//
LOCUS       KCWK01004106             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:20415:11198
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004106
VERSION     KCWK01004106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20415:11198"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69844.1"
                     /translation="DYYCQSYDSSLRGVLF"
     J_segment       413..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           87 a          155 c          132 g          114 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctacacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcactgg ggccagttcc aacattggag gtttttatgt acagtggtac cagcaccttc
      241 caggaacggc ccccaaactc ctcatctatg aaaatgataa gcgaccctca ggggtttcgg
      301 atcgattctc tggttcccag tctggtacct cagcctccct gaccatcgct ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagtttgcgt ggtgtgttgt
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01004107             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:7194:7100
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004107
VERSION     KCWK01004107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7194:7100"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69845.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          141 c          133 g           94 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgaa ttgactcagt
      121 caccctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa aactgtgcac tggtaccaac agaagccacc gcagggccct gtattggtca
      241 tctttgctga tagtagacgg ccctcaggga tccctgagcg attctctggc tccaattcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004108             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:10843:9952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004108
VERSION     KCWK01004108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10843:9952"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..408
                     /note="immunoglobulin light chain variable region"
     V_region        63..408
     V_segment       63..371
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69846.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       375..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           86 a          152 c          106 g          102 t
ORIGIN      
        1 acatgggggc cctgactcct ctcctcctcc tgctcctctc tcactgcaca ggttccctct
       61 cccagcctgt gctgactcag ccaccctccc tgtctgcatc cccgggagca tcggccagac
      121 tcccctgcac cctgagcagt gacctcaata ttggcaataa aaacatgtac tggtaccagc
      181 agaagccagg gagcgctccc aagttattcc tgtactacta ctccgactca gacatgcagc
      241 tgggacctgg ggtccccaat cgagtctctg gctccaagga gacctcaagt catacagcgt
      301 ttttgctcat ctctgggctc cagcctgagg acgaggccga ttattactgt caggtgtatg
      361 acagtagtgc tgtattattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004109             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14322:14574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004109
VERSION     KCWK01004109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14322:14574"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69847.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           89 a          158 c          119 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacgtacac tggtaccagc agaagccagg gagtcccccc cggtttcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccagtaa tgtttcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004110             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:21795:10420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004110
VERSION     KCWK01004110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21795:10420"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..455
                     /note="immunoglobulin light chain variable region"
     V_region        110..455
     V_segment       110..418
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69848.1"
                     /translation="DYHCQVYDGSAVLF"
     J_segment       422..455
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           90 a          166 c          124 g          113 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      181 gagtagtgac ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag
      241 cgctcccagg ttattcctgt actacttctc cgactcagac aagcagttgg gacctggggt
      301 ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgtttt tactcatctc
      361 tgggctccag cctgaggacg aggccgatta tcactgtcag gtgtatgacg gtagtgctgt
      421 tttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01004111             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:24692:9918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004111
VERSION     KCWK01004111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:24692:9918"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..336
                     /note="immunoglobulin light chain variable region"
     V_region        8..336
     V_segment       8..296
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69849.1"
                     /translation="DYYCAIGHSSGNYIF"
     J_segment       303..336
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           76 a          115 c           96 g           87 t
ORIGIN      
        1 acatgggggc ctccttctca gcatctcctg gagcttcagc cagtctcaca tgcaccttca
       61 gcggtggcat caatgttgct ggctaccaca tacactggta ccagcagaag ccagggagtc
      121 ctccccggtt tcttctgaga tacaagtcag actcagataa gggccagggc tctggagtcc
      181 ccagccgctt ctctggatcc aaggatgctt cagcgaacac aggaatttta cgcatctctg
      241 ggctccagtc tgaggatgag gctgactatt actgtgccat tgggcacagc agcggtaatt
      301 atatcttcgg tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg
      361 tcactctgtt cccg
//
LOCUS       KCWK01004112             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18575:7309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004112
VERSION     KCWK01004112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18575:7309"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69850.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          152 c          122 g          112 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatct tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004113             366 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:9529:11270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004113
VERSION     KCWK01004113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 366)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9529:11270"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..328
                     /note="immunoglobulin light chain variable region"
     V_region        8..328
     V_segment       8..284
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <256..>300
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69851.1"
                     /translation="DYYCSSYAGSNNFLF"
     J_segment       295..328
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        329..>366
                     /gene="IGLC"
BASE COUNT           75 a          115 c           88 g           88 t
ORIGIN      
        1 acatgggcga ctcagcctcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc
       61 tgcactggaa ccagcactaa tattggatat tataatgctg tgtcttggta ccaacaccat
      121 ccaggcaaag cccccagact catgatttat gacgtcagta agcggccctc aggggtctct
      181 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag
      241 actgaggatg aggctgatta ttactgcagc tcatatgcag gcagcaacaa ttttttattc
      301 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      361 ttcccg
//
LOCUS       KCWK01004114             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:12688:13605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004114
VERSION     KCWK01004114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12688:13605"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69852.1"
                     /translation="DYYCAAWDNSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           97 a          157 c          121 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag actcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gataatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004115             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:15621:9364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004115
VERSION     KCWK01004115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:15621:9364"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69853.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          157 c          127 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca agtcccagga
      241 acagctccca aactcctcat ctattatagt gatcaccgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgaggggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004116             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:20601:17894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004116
VERSION     KCWK01004116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20601:17894"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69854.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          150 c          120 g          107 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag cagctccaac
      181 attggagatt tttatgtgca gtggtaccag caccttccag gaacggcccc cagactcctc
      241 atctatgaaa ataataagcg accctcaggg gtttctgatc gattctctgg ctcccagtct
      301 ggaacctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgccagtcct atgacagcag tttgattgct gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004117             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:12878:16341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004117
VERSION     KCWK01004117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:12878:16341"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69855.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          163 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004118             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:10230:12776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004118
VERSION     KCWK01004118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10230:12776"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..436
                     /note="immunoglobulin light chain variable region"
     V_region        90..436
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69856.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           89 a          164 c          110 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccggcca acctccctct
      121 cagcatctcc gcgagcatca gccagactca gctgcacctt tagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc ggttccggga
      421 cccggctcac cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004119             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:14725:15303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004119
VERSION     KCWK01004119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14725:15303"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69857.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          156 c          126 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtcca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaac agtgtcgcca tctcctgttc
      181 tggaggcagc tccaacatcg gaagtcatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatgatga tcaacgagcc tcaggtgtct ctggccgatt
      301 ctctggctcc aggtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agaggttaca tcttcggtga
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01004120             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:7547:4828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004120
VERSION     KCWK01004120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7547:4828"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69858.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          143 c          139 g           93 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accttcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccagcg cacgcccctg tgctggtcat
      241 ctatgctaat agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg ggtgaggctg actattactg
      361 tcaggtgtgg gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004121             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:17312:11993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004121
VERSION     KCWK01004121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17312:11993"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..403
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69859.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       405..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           87 a          151 c          124 g          114 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggttcag gctgccccga
      121 ctcagcctcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tgttgggtat tataacgctg tgtcttggta ccaacagcat ccaggcaaag
      241 cccccaaact catgatttat gacgtcatta agcggccctc aggggtttct gatcgcttct
      301 ctggctccaa gtctggcgac acggcctccc tgaccatctc tgggctccag gctgaggatg
      361 aggctgatta ttactgcagc tcatatgcag gcagaaataa ttttttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004122             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:13300:10713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004122
VERSION     KCWK01004122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13300:10713"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69860.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          162 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggatc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004123             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:16051:14276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004123
VERSION     KCWK01004123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16051:14276"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69861.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       415..449
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           92 a          155 c          127 g          113 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcacgatctc
      181 ctgcagtggg agcaactcca acattggata ttattatgtg cagtggtacc agcagcttcc
      241 aggaacggcc cccaaactcc tcatctatga aaataataag cgaccccctg gggtttctga
      301 tcgattctct ggctcccagt ctggtacctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccactc ctatgacagc agtttgagtg gtgtcttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01004124             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:12565:16281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004124
VERSION     KCWK01004124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12565:16281"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..437
                     /note="immunoglobulin light chain variable region"
     V_region        113..437
     V_segment       113..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69862.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           91 a          150 c          134 g          100 t
ORIGIN      
        1 acatgggggc tgccctgtct gggtctcagg aggcagcatt gacggtgcct cagccatggc
       61 ctggaccctt ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctttga
      121 gttgactcag ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg
      181 gggagacaac attggaatta aatttgtcca ctggtaccag cagaagccag cgcaggcccc
      241 tgtgaaggtc atctatgctg atgacaaacg gccctcaggg atccctgaga gattctctgg
      301 ctccaattca gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc
      361 tgactattcc tgtcaggtgt gggacagtga gactgattat tacatcttcg gtactgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004125             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:24499:3565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004125
VERSION     KCWK01004125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:24499:3565"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69863.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          156 c          117 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtatcagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc tgggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aatacaggga ttttacacat ctctggtttc cagtctgagg
      361 atgaggctga ctattactgt gccattggcc acggcagcgg tgattacatc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004126             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:28975:11667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004126
VERSION     KCWK01004126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:28975:11667"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69864.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       403..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           85 a          162 c          127 g           97 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtggt gactcagtcg
      121 tcctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcggtggg
      181 cacagcgact acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggtatttg
      241 atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctga tcgcttctcc
      301 ggctccagct ccggggctga gcgctacctc accatcacca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggagact ggcattcagg tgttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004127             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:6728:15642
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004127
VERSION     KCWK01004127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:6728:15642"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69865.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt ggtcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004128             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:8437:15392
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004128
VERSION     KCWK01004128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:8437:15392"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..277
                     /note="immunoglobulin light chain variable region"
     V_region        7..277
     V_segment       7..238
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <205..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69866.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       240..277
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>315
                     /gene="IGLC"
BASE COUNT           64 a           94 c           83 g           74 t
ORIGIN      
        1 acatggggca tcaatgttgc tgtctaccac gtacactggt accaacagaa gccagggagt
       61 cccccccggt atcttctgag gtacaaatca gactcagata agggccaggg ctctggggtc
      121 cctagccgct tctctggatc cagtaatgct tcagcgaaca cagggatttt acgcatttct
      181 gggctccagt ctgaggatga ggctgactat tactgtgcca ttgggcacag cagcggtctt
      241 tacatcttcg gtgctgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg
      301 gtcactctgt tcccg
//
LOCUS       KCWK01004129             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:21831:9006
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004129
VERSION     KCWK01004129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21831:9006"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69867.1"
                     /translation="DYYCSSYAGSNILVF"
     J_segment       404..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          154 c          122 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtagttata accgtgtctc ctggtaccaa catcacccag acaaagcccc
      241 caaagtcatg atttatgagg gcagtcagcg gccctcaggg gtctctgatc gcttctctgc
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattat tgcagctcat atgcaggcag caatattttg gttttcggcg gagggacccg
      421 gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004130             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:21310:15776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004130
VERSION     KCWK01004130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21310:15776"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69868.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          105 a          137 c          121 g          100 t
ORIGIN      
        1 acatgggggt ggttccagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tctgtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatactcagt ggttccagca gcagccaggc caggcccctt tcctggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacaatt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagta gacagcagtg gaaatcttcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004131             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:17946:12486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004131
VERSION     KCWK01004131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17946:12486"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69869.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          147 c          131 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctccgatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa gagtgtgcac tggtaccaac acaagccacc gcaggcccct atcctggtca
      241 tctattatta taccgaacgg ccctcggcga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacactact attgatcatg gctttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004132             326 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:13472:5795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004132
VERSION     KCWK01004132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 326)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13472:5795"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..288
                     /note="immunoglobulin light chain variable region"
     V_region        8..288
     V_segment       8..252
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>260
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69870.1"
                     /translation="NYYCCSYTTSGTYVF"
     J_segment       253..288
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        289..>326
                     /gene="IGLC"
BASE COUNT           65 a          104 c           78 g           79 t
ORIGIN      
        1 acatgggggt caccatctcc tgcactggaa ccagcagtga cattggtggt cataactctg
       61 tctcctggta ccaacaaaac ccaggcaaag cccccaaact catgatttat ggtgtcagta
      121 atcggccctc tggggtctct gatcgcttct ctggctccaa gtctggcgac acggcctccc
      181 tgaccatctc tgggctccag gctgaggacg aggctaatta ttactgttgt tcatatacaa
      241 ccagtggcac ttacgtcttc ggtgctggga cccggctcac cgtcctaggt cagcccaagg
      301 cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004133             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:17132:22179
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004133
VERSION     KCWK01004133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17132:22179"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    52..382
                     /note="immunoglobulin light chain variable region"
     V_region        52..382
     V_segment       52..345
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <307..>354
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69871.1"
                     /translation="DYYCAAWDDRLTGYVF"
     J_segment       352..382
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>420
                     /gene="IGLC"
BASE COUNT           76 a          140 c          107 g           97 t
ORIGIN      
        1 acatgggctc tcctcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
       61 ctgactcagc ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct
      121 ggaagcagct ccaacatcgg gagcaatagt gtatcctggt accagctgct cccagaaacg
      181 gctcccaaac tcctcatcta ttataataat cggcgagcct caggtgtctc tgaccgattc
      241 tctggctcca agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat
      301 gagggtgatt attactgcgc agcatgggat gatcgcctga ccggttacgt gttcggtgtt
      361 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004134             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:8219:6874
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004134
VERSION     KCWK01004134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8219:6874"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69872.1"
                     /translation="DYYCQVYDSTSNVLF"
     J_segment       414..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          164 c          119 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tatatgacag tacttctaac gtattattcg
      421 gaagagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004135             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:20911:12377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004135
VERSION     KCWK01004135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:20911:12377"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69873.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          148 c          131 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccagggcag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004136             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:15925:10577
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004136
VERSION     KCWK01004136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:15925:10577"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69874.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       392..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          139 c          137 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcaggc
      121 accctcgatt tcagtgtccc ccggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 gtatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacatgaata gtcatcatct attattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004137             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:14993:16800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004137
VERSION     KCWK01004137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14993:16800"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..312
                     /note="immunoglobulin light chain variable region"
     V_region        10..312
     V_segment       10..276
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <240..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69875.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       280..312
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>350
                     /gene="IGLC"
BASE COUNT           76 a          102 c          104 g           68 t
ORIGIN      
        1 acatggggtc accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg
       61 gagacaacat tggaactaaa actgtgcact ggtaccaaca gaagccaccg cagggccctg
      121 tattggtcat ctttgctgat agtagacggc cctcagggat ccctgagcga ttctctggct
      181 ccaattcagg gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg
      241 actattactg tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc
      301 taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004138             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:15153:4370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004138
VERSION     KCWK01004138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15153:4370"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69876.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          153 c          116 g          113 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcactgttg
      181 ctggctacca tatatattgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatatc tggactccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacaca gcagcggtga ttatatcttc ggtgctggga
      421 cccgtctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttccct
//
LOCUS       KCWK01004139             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:18806:16326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004139
VERSION     KCWK01004139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:18806:16326"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..262
                     /note="immunoglobulin light chain variable region"
     V_region        5..262
     V_segment       5..225
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <187..>234
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69877.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       228..262
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        263..>300
                     /gene="IGLC"
BASE COUNT           62 a           89 c           87 g           62 t
ORIGIN      
        1 acatggggag acaacattgg aactaaatat gtgcactggt accagcagaa gccagcgcag
       61 gcccctgtgt tggtcatcta tgctgatacc agacggccct cagggatccc tgagcgattc
      121 tctggctcca actcagggaa caccgccacc ctgaccatca gcggtgtcga ggccgggtat
      181 gaggctgact atttctgtca ggtgtgggac gatagtagtg atcatccggt attcggcgga
      241 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004140             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:8973:7886
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004140
VERSION     KCWK01004140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8973:7886"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69878.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          140 c          136 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctgtgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004141             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:19754:19793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004141
VERSION     KCWK01004141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19754:19793"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69879.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          158 c          119 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctct gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttcttggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcggactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacgcaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004142             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:18621:20061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004142
VERSION     KCWK01004142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18621:20061"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    132..336
                     /note="immunoglobulin light chain variable region"
     V_region        132..336
     V_segment       132..299
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <261..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69880.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       301..336
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           68 a          127 c           93 g           86 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctcgt ctcctctcct cctcaccctt ttcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cacggccccc aaactcctcg tctatgacaa taataagcga ccctcagggg
      181 tttctgaccg attctctggc tccaagtctg gttcctcagc caccctgacc atcactgggc
      241 tccagactga ggatgaggct gattattact gccagtccta tgacagcagt ctgagtgctc
      301 gggtattcgg cggagggacc cggctaaccg tcctagctca gcccaaggct gccccctcgg
      361 tcactctctt cccg
//
LOCUS       KCWK01004143             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:7254:9466
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004143
VERSION     KCWK01004143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7254:9466"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69881.1"
                     /translation="DYYCQVWDISIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          144 c          133 g          102 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gcctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccaggg tcacctgtgg aggagacaac
      181 cttggatatg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctaacc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattag tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004144             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:15194:6533
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004144
VERSION     KCWK01004144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:15194:6533"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..332
                     /note="immunoglobulin light chain variable region"
     V_region        8..332
     V_segment       8..295
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <257..>304
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69882.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       298..332
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        333..>370
                     /gene="IGLC"
BASE COUNT           69 a          117 c           99 g           85 t
ORIGIN      
        1 acatggggtg ctgactcagc caccctcagc gtctggggct cccgggcaga gtgtcaccat
       61 ctcttgttct ggaagcatct ccagcattgg aagtagtgat gtatgttggt accagcaact
      121 cccaggaacg gcccccaaac tcctcatcaa ttatagtgat cagcgactct caggggtccc
      181 tgaccgattc tctggctcta agtctggcac ctcagcctcc ctggccatca ctggtctccg
      241 atctgaggat gaggctgatt attactgtgc agcctgggat agcagcctga gcagtccggt
      301 attcggcgga gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac
      361 tctcttcccg
//
LOCUS       KCWK01004145             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:27308:6304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004145
VERSION     KCWK01004145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:27308:6304"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69883.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       403..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>469
                     /gene="IGLC"
BASE COUNT           84 a          162 c          126 g           97 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtggt gactcagtcg
      121 tcctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcggtggg
      181 cacagcgact acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggtatttg
      241 atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctga tcgcttctcc
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggagact ggcattcagg tgttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggccccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004146             398 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:25154:16111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004146
VERSION     KCWK01004146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 398)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25154:16111"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    15..360
                     /note="immunoglobulin light chain variable region"
     V_region        15..360
     V_segment       15..323
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <291..>332
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69884.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       324..360
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        361..>398
                     /gene="IGLC"
BASE COUNT           82 a          129 c          100 g           87 t
ORIGIN      
        1 acatgggcct ctcccagcct gtgctgactc agccaccctc cctgtctgca tccccgggag
       61 catcggccag actcccctgc accctgagca gtgacctcag tgttggtaat aaaaacatgt
      121 actggtacca acagaagcca gggagcgctc ccaggttatt cctgtactac tactccgact
      181 cagacaagca gctgggacct ggggtcccca atcgagtctc tggctccaag gagacctcaa
      241 ctaacacagc gtttttgctc atctctgggc tccagcctga ggacgaggcc gattattact
      301 gtcaggtgta tgacagtagt gctgtgttat tcggaggagg gacccgactg accgtcctag
      361 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004147             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:7024:3545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004147
VERSION     KCWK01004147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7024:3545"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69885.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          162 c          118 g          110 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt aataaaaaca tgtactggta ccaacagaag ccagggagcg ctcccaggtt
      241 attcctatac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caactaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtttgacagt agtgctgtgt tattcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01004148             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:21775:11999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004148
VERSION     KCWK01004148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:21775:11999"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69886.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       394..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          148 c          120 g          105 t
ORIGIN      
        1 acatggggag ctgtgggctc agaagcagaa ctctgggtcc tctccaccat gacctggacc
       61 cctcccctgc tcatcctcct cactctctgc acaggttccg tggtttcctc tgagctgact
      121 caggagcctg cattgtctgt ggccttggga caaacagtca ggatgacctg ccaaggagac
      181 agcctcaaaa cctattatgc aagctggtac cagcagaagc caggccaggt ccctgtgctg
      241 gtcatctatg gtaacaacta ccggccctca gggatcccag gccgattctc tgtctcctgg
      301 tcaggaaaca caggttcctt gaccatcact gcggctcagg tggaagatga ggctgactat
      361 tactgtaagt cctgggacag cagtggtacc cattacatct tcggtgctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01004149             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:8961:12823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004149
VERSION     KCWK01004149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8961:12823"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69887.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       401..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          153 c          112 g          116 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg ggctcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcatctcc tggagcatca gccagactca cctgcacctt gaacagtggc atcagtgttg
      181 ctaattacag gatattctgg taccaccaga agccagggag tcctccccgg tatcttctga
      241 actaccacac agactcagat attcatcagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcagggattt tactcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtatg atttggcaca acaatgctta ttgggttttc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004150             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:26334:15435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004150
VERSION     KCWK01004150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:26334:15435"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69888.1"
                     /translation="DYYCGIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           96 a          156 c          117 g          107 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cacgggtggc atcaatgttg
      181 ctgactacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtggc attgggcaca gcagcggtga ttacatcttc gctgatggga
      421 cccgactcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004151             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12263:10573
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004151
VERSION     KCWK01004151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12263:10573"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..403
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69889.1"
                     /translation="DYYCSSYADSNIFFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          153 c          119 g          113 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcaga cagtaatatt ttcttcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004152             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:17260:18451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004152
VERSION     KCWK01004152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17260:18451"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69890.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           89 a          147 c          128 g           97 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc cgatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtaagag tgtgcactgg taccaacaca agccaccgca ggcccctatc ctggtcatct
      241 attattatac cgaacggccc tcggcgatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cactactatt gatcatggct ttttcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004153             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:18336:17518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004153
VERSION     KCWK01004153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18336:17518"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69891.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT          108 a          135 c          122 g           99 t
ORIGIN      
        1 acatggggtg tggttctagg aggaagagct ctgggtgtct caccatgacc tggaccactg
       61 ttctgctccc ctttctcact ctctgcacag gctctgaggc ctcctatgac ctgacacagc
      121 caccctcagt gtcagtgtcc ccagggcaga cggccaggat cacctgctct ggagaaatac
      181 tggcaaaaaa atatactcag tggttccagc agaagtcagg ccagggccct agactggtga
      241 tatataaaga cagtgagagg ccctcaggga tccctgagcg attctctagc tccagttcag
      301 ggacaacagt caccttgacc atcagcgggg cccagacaga agatgaggct gactattact
      361 gtcaatcagc agacagaagt cctaatcatg tgtttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004154             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:27064:15774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004154
VERSION     KCWK01004154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:27064:15774"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..433
                     /note="immunoglobulin light chain variable region"
     V_region        85..433
     V_segment       85..394
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69892.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       399..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           90 a          158 c          110 g          113 t
ORIGIN      
        1 acatggggga aagaggctgt gtccaccatg gcctggactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctcccagcct gtgctgaccc agccaacctc cctctcagca
      121 tctccgggag catcagtcag actcagctgc accttgagca gtggcatcaa tgttggttct
      181 tacaccatat tctggtacca gcagaagcca gggagtcctc cccggttcct tctgtactac
      241 tactcagact caaataatca ccagggctct ggagtcccca gccgcttctc tggatccaaa
      301 gatgcttcag ccaatgcagg gcttttactg atctctgggc tccagtctga agatgaggct
      361 gactattact gtgccatgtg gcacagcagc gcttatgcct tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004155             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:22698:13893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004155
VERSION     KCWK01004155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22698:13893"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69893.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          153 c          121 g          112 t
ORIGIN      
        1 acatgggggc ttggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caccatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatggagg cagcaatagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004156             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:14274:19019
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004156
VERSION     KCWK01004156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14274:19019"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..237
                     /note="immunoglobulin light chain variable region"
     V_region        10..237
     V_segment       10..199
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <162..>209
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69894.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       205..237
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>275
                     /gene="IGLC"
BASE COUNT           54 a           85 c           85 g           51 t
ORIGIN      
        1 acatggggaa ctggtaccag cagaagccag cgcaggcccc tgtgctggtc atctatgctg
       61 atagcgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca gggaacacgg
      121 ccaccctgac catcagcggg gtcgaggccg ggggtgaggc tgactattac tgtcaggtgt
      181 gggacatgcg tagtgatcaa ccgctattcg gcggagggac ccggctaacc gtcctaggtc
      241 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004157             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:15023:2742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004157
VERSION     KCWK01004157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15023:2742"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69895.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          159 c          112 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctcccctg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004158             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:17765:19407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004158
VERSION     KCWK01004158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17765:19407"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69896.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          128 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtacact ggtaccagca caagccaccg caggcccctg ttctgctcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttgttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc cag
//
LOCUS       KCWK01004159             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:23027:13397
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004159
VERSION     KCWK01004159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23027:13397"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69897.1"
                     /translation="DYSCQVWDSESDYYVF"
     J_segment       389..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          146 c          133 g           96 t
ORIGIN      
        1 acatgggctg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag gctctgcgac ctcctttgag ctgactcagc
      121 caccctcggt gtcagcggcc tcaggacaga cggccaggat cacctgtagg ggagacaaca
      181 ttggaattaa atttgtccac tggtaccagc agaagccagc gcaggcccct gtgaaggtca
      241 tctatgctga tgacaaacgg ccctcaggga tccctgagag attctctggc tccaattcag
      301 gggacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattcct
      361 gtcaggtgtg ggacagtgag agtgattatt acgtcttcgg tgctgggacc cggctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004160             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:6081:6122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004160
VERSION     KCWK01004160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6081:6122"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69898.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           96 a          163 c          110 g          107 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcaactcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcccccccga tatcttctga
      241 gtcacaaatc agactcagat aagggccagg cctctggagt ccccagccgc ttctctggat
      301 ccaaaaatgc ttcgacaaac acaggcattt tacacatctc tgggctccag tctgaggatg
      361 aggctgacta tttctgtgcc attggacaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004161             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:21814:7401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004161
VERSION     KCWK01004161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21814:7401"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69899.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       411..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           88 a          156 c          128 g          114 t
ORIGIN      
        1 acatggggct ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggaggt tattatgtgc agtggtacca gcagcttcca
      241 gggacggccc ccaaactcct catctatgaa aatgataaac gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tgattcctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gcttgagtgt tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004162             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:12730:13341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004162
VERSION     KCWK01004162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:12730:13341"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69900.1"
                     /translation="DYYCSTWDSSLTGGLF"
     J_segment       407..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           98 a          156 c          122 g          106 t
ORIGIN      
        1 acatggggca gcttcagctg tggctagaga agacaggact caggacaatc tccagcatgg
       61 cctgcttccc tctcatcctc accgtcctca ctcactgtgc aggatcctgg gcccagtctg
      121 tgctgactca accaccctca gcgtctgggg cccccgggca gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaatt atgtatactg gtaccagcag ttctcaggga
      241 aggcccccaa actcctcatc cataataata atcagcgacc ctcaggggtc cctgatcgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagtccgagg
      361 atgaggctga ttattactgc tcaacatggg atagcagtct gaccggtggc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004163             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:24121:11928
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004163
VERSION     KCWK01004163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24121:11928"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69901.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          148 c          130 g           96 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gtactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004164             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:18246:11031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004164
VERSION     KCWK01004164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18246:11031"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69902.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       401..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           96 a          155 c          110 g          115 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcatctcc tggagcatca gccagactca cctgcacctt gaacagtggc atcagtgttg
      181 ctaattacag gatattctgg taccaccaga agccagggag tcctccccgg tatcttctga
      241 actaccacac agactcagat attcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcagggattt tactcatctc tggactccac tctgaggatg
      361 aggctgacta ttactgtatg atttggcaca acaatgctta ttgggttttc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004165             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:6193:12633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004165
VERSION     KCWK01004165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6193:12633"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..350
                     /note="immunoglobulin light chain variable region"
     V_region        20..350
     V_segment       20..313
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <269..>322
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69903.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       314..350
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        351..>388
                     /gene="IGLC"
BASE COUNT           78 a          118 c          113 g           79 t
ORIGIN      
        1 acatgggggc tctgtggcct cctatgagct gactcagcca ccctcagtgt cggtgtcccc
       61 aggacagaca gccagcatca cctgctctgg aaataaattg gggaatgtat atgcttactg
      121 gttccagcag aagccaggcc aggcccctgt agtggtcatc tacaaagata ccaaccggcc
      181 ctcagggatc cctgagcgat tctctggctc cgactcaggg aacacggcca ccctgaccat
      241 cagcagggtc gaggctgggg atgaggccga ctatttttgt gctgcagcct atggcagtgg
      301 cagcagctgg cagtgggtat tcggcggagg gacccggcta atcgtcctag gtcagcccaa
      361 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004166             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:6139:11121
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004166
VERSION     KCWK01004166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6139:11121"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..396
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69904.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           93 a          161 c          114 g          106 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctct
      121 gcatctcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 gcctaccaca tacactggta ccagcagaag ccagggagtc ctccccggta tcttctgaga
      241 tacaaatcag actcagataa ggaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgcct cagcgaacac agggatttta cgcatctctg ggctccagtc tgaggatgag
      361 gctgactact actgtgccat tgggcacagc agcggtgatt acatcttcgc tgctgggacc
      421 cgcctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004167             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:17986:14028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004167
VERSION     KCWK01004167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17986:14028"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69905.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          120 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctcttgctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004168             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:8788:9814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004168
VERSION     KCWK01004168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:8788:9814"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..388
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69906.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       390..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          149 c          122 g          107 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag cagctccaac
      181 attggaggtt attatgtgca gtggtaccag cagcttccag gagcggcccc caaactcctc
      241 atctatgaaa atgataaacg accctcaggg gtttctgatc gattctctgg ctcccagtct
      301 gattcctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgccagtcct atgacagcag cttgagtgtt gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004169             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:14156:15061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004169
VERSION     KCWK01004169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14156:15061"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..393
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69907.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           87 a          152 c          124 g          106 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgagtcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtctccatc tcctgttctg gaagcagctc
      181 caacatcgga agtcatagtg tctcctggta ccagcagctc ccaggaacag ctcccaaact
      241 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctctca
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag gccgaggatg aggctgatta
      361 ttactgcgca gcatgggatg atagtctgag cggatacatc ttcggtgctg ggacccggct
      421 cgccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004170             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:15597:17835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004170
VERSION     KCWK01004170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15597:17835"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..336
                     /note="immunoglobulin light chain variable region"
     V_region        12..336
     V_segment       12..298
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <261..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69908.1"
                     /translation="DYYCQVWDTSIDHGLF"
     J_segment       300..336
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           82 a          115 c          103 g           74 t
ORIGIN      
        1 acatgggggc ctcctatgat ctgactcagc caccctcggt gtcagtgtcc ccaggacaga
       61 cggccaggat cacctgtgag ggagacaaca ttggaagtca aagtgtgcac tggtaccagc
      121 acaagccacc gcaggcccct atactggtca tcttttatta taccgaacgg ccctcaggaa
      181 tccctgagcg attctctggc tccaaatcag ggaacaccgc caccctgacc atcagcgggg
      241 tcgaggccgg ggatgaggct gactattact gtcaggtgtg ggacacaagt attgatcacg
      301 gcttattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      361 tcactctctt cccg
//
LOCUS       KCWK01004171             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:23773:11767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004171
VERSION     KCWK01004171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23773:11767"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..417
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69909.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       418..454
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           94 a          157 c          132 g          109 t
ORIGIN      
        1 acatgggggg gtgaagcgca gcttcagctg tgggtacaga aggcaggact caggacaatc
       61 tccagcatgg cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg
      121 gcccagtctg tgctgactca gcctccctca gcgtctgagg ccgccaggaa cagtgtcgcc
      181 atctcctgtt ctggaagcag ctccaacatc ggaagtcata gtgtatcctg gtaccagcag
      241 ctcccaggaa cagctcccaa actcctcatc tattatgatg atcaacgagc ctcgggtgtc
      301 tctgaccgat tctctggctc caggtctggc acgtcagcct ccctggccat cagtgggctc
      361 cagaccgagg atgaggctga ttattactgc gcagcatggg atgatagcct gagaggttac
      421 atcttcggtg atgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCWK01004172             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:5981:4708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004172
VERSION     KCWK01004172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5981:4708"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..252
                     /note="immunoglobulin light chain variable region"
     V_region        8..252
     V_segment       8..214
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <177..>224
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69910.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       220..252
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        253..>290
                     /gene="IGLC"
BASE COUNT           60 a           84 c           91 g           55 t
ORIGIN      
        1 acatgggtgg aagtgaagtt gtgaactggt accagaagaa gccagcgcag gcccctgcac
       61 tggtcatcta tgctgatagc gaacggccct cagggatccc tgagcgattc tctggctcca
      121 aatcagggaa cacggccacc ctgaccatca ggggggtcga ggccgggggt gaggctgact
      181 attactgtca ggtgtgggac atgcgtagtg atcaaccgct attcggcgga gggacccggc
      241 taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004173             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:10558:16810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004173
VERSION     KCWK01004173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10558:16810"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..389
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69911.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          143 c          133 g           93 t
ORIGIN      
        1 acatgggggc tgggtctcag gaggcagcat tgacggtgcc tcagccatgg cctggaccct
       61 tctcctcctc ggcctcctcg cttactgcac aggctctgcg acctcctatg aactgactca
      121 gtcaccctca gtgtcagcgg cctcaggaca gccggccagg atcacctgtg ggggagacaa
      181 cattggaatt aaaactgtac actggtacca gcagaagcca ccgcagggcc ctgtattggt
      241 catctttgct gatagtaagc ggcccacagg gatccctgag cgattctctg gctccaactc
      301 agggaacacc gccaccctga ccatcagcag ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta gtagtaaatg gatattcggc ggggggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004174             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10309:8779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004174
VERSION     KCWK01004174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10309:8779"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69912.1"
                     /translation="DYYCQVYDSGANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          164 c          124 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagcgttgg tagtaaaaac atgtactggt accagcggaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tggtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004175             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:12244:20844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004175
VERSION     KCWK01004175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12244:20844"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69913.1"
                     /translation="DYYCQVWDSSSEWVF"
     J_segment       385..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           92 a          142 c          133 g           91 t
ORIGIN      
        1 acatgggggt ctcaggaggc agcattgacg gtgcctcagc catggcctgg acccttctcc
       61 tcctcggcct cctcgcttac tgcacagact ctgcgacctc ctatgaattg actcaggcac
      121 cctcagtgtc agcggcctca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtaaaac tgtgcactgg taccaacaga aggcagcgca ggcccctgtg ctggtcatct
      241 ttgctgatag caaacggccc tcagggatcc ctgaccgatt ctctggctcc aactcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cagtagtagt gaatgggttt tcggcggagg gacccggcta accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004176             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:25687:12910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004176
VERSION     KCWK01004176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:25687:12910"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69914.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          152 c          116 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttctggaag cagctccaac
      181 atcggaagta atagtgtttc ctggtaccag caactcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg accctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagcggt tacattttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004177             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:15784:11570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004177
VERSION     KCWK01004177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15784:11570"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69915.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          153 c          113 g          107 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgttgac tcagcctccc
      121 tcagcgtctg aggccgcctg gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta atagtgtatc ctggtaccaa caactcccag aaacggctcc caaactcctc
      241 atgtattata atcatcggcg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcccttcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagtat gggatgatag cctgaccggt tacatcttcg gtactgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004178             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:14598:13068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004178
VERSION     KCWK01004178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:14598:13068"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69916.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          150 c          117 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggacg gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004179             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:17071:13693
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004179
VERSION     KCWK01004179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17071:13693"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..392
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69917.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       394..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          151 c          123 g          107 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctcctct
       61 cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc tgacgcagcc
      121 gccctcagtg tctggggcgc ccgggcagag ggtcaccctc tcctgcactg ggagcagctc
      181 caacattgga gattattatg tgcagtggta ccagcagctt ccaggaacgg cccccaaact
      241 cctcatctat gaaaataata agcgaccctc aggggtttct gatcgattct ctggctccca
      301 gtctggtacc tcagcctccc tgaccatcac tggactccag tctgacgatg aggctgatta
      361 ttactgtcag tcctatgata gcagcctgag tgttgtgtta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004180             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:18973:20457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004180
VERSION     KCWK01004180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18973:20457"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69918.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          161 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg aactggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004181             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:14531:15947
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004181
VERSION     KCWK01004181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14531:15947"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69919.1"
                     /translation="DYYCQVWDSDSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           96 a          142 c          132 g           91 t
ORIGIN      
        1 acatggggtg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gtactgcgac ctcctatgaa ctgactcagc
      121 caccctcagt gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa aaatgtgcac tggtaccagc agaagccagc gcagggccct gtattggtca
      241 tgtttgctga taccagacgg ccctcaggga tccctgaccg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtgat agtaaatgga tattcggcgg agggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004182             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:22317:11098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004182
VERSION     KCWK01004182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22317:11098"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..237
                     /note="immunoglobulin light chain variable region"
     V_region        7..237
     V_segment       7..200
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <168..>209
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69920.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       201..237
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>275
                     /gene="IGLC"
BASE COUNT           52 a           82 c           82 g           59 t
ORIGIN      
        1 acatggggca tcagcagcag caagggaagg cccctcggtt cttgatgtgg cttaagagtg
       61 atggcagcca caccaagggg gacggggtcc ctgatcgctt ctcaggctcc agctccgggg
      121 ctgagcgcta cctcaccatc tccaacctcc agtctgagga tgaggctgat tattactgtc
      181 agacctggga tattggcatt tgggtattcg gcggagggac ccggctaatc gtcctaggtc
      241 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004183             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11665:22159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004183
VERSION     KCWK01004183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11665:22159"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69921.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          130 g           95 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaagcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004184             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:23667:20173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004184
VERSION     KCWK01004184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23667:20173"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..400
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69922.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           88 a          150 c          128 g          111 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgttg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg tcaccatctc ctgcactggg
      181 agcagctcca acatcggggc gggtttttat gtttcctggt accagcagtt cccaggaaca
      241 gcccccaaac tcctcatctt tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggttc ctcagcctcc ctgaccatca ctggactcca atctgaggat
      361 gaggctgatt attattgttc atcatgggaa agcagcctga attgggtatt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004185             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:10884:3722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004185
VERSION     KCWK01004185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10884:3722"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69923.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          158 c          128 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtc cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaggca gctccaacat cggcagtcat agtgtatcct ggtaccagca gctcccagga
      241 gcagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctggccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004186             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:15856:8147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004186
VERSION     KCWK01004186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15856:8147"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69924.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           92 a          142 c          133 g           94 t
ORIGIN      
        1 acatggggtg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag actctgcgac ctcctatgaa ttgactcagt
      121 cgccctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacgaca
      181 ttggaactaa aactgtgcac tggtaccaac agaagccacc gcagggccct ctattggtca
      241 tctttgctga tagtagacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaagcgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004187             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:19629:7116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004187
VERSION     KCWK01004187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19629:7116"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69925.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           89 a          142 c          126 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactccct atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004188             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:4869:11897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004188
VERSION     KCWK01004188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:4869:11897"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..403
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69926.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       408..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          152 c          123 g          112 t
ORIGIN      
        1 acatgggggg cttggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccccga
      121 ctcagactcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tattgggtat tatcatgctg tgtcttggta ccagcatcat ccaggcaaag
      241 cccccaaact catgatttat gaggtcaata aacggcccgc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag actgaggatg
      361 aggctgatta ttactgcagc tcatatggag gcagcaatag tttattcttc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004189             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:15558:10326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004189
VERSION     KCWK01004189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15558:10326"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69927.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           84 a          157 c          118 g          116 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcaag ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accttctcct gcactggaac
      181 cggcagtgat tttgggtctt ataatgctgt gtcttggtac caacagcatc caggcaaagc
      241 cccccaactc ataatttttg aggtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgctgct catatgtagg cagcaacact tacatcttcg atgttgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004190             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:16160:15745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004190
VERSION     KCWK01004190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16160:15745"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69928.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           96 a          162 c          113 g          109 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcaa ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctgcct accacataca ctggtaccag cagaagccag ggagtccccc ccggtatctt
      241 ctgagttaca aatcagactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaaa atgcttcaac gaacacaggc attttacaca tctctgggct ccagtctgag
      361 gatgaggctg actatttctg tgccattgga cacagcagcg gtccttacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004191             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:7579:13718
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004191
VERSION     KCWK01004191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:7579:13718"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..254
                     /note="immunoglobulin light chain variable region"
     V_region        9..254
     V_segment       9..217
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69929.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       224..254
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           57 a           86 c           87 g           62 t
ORIGIN      
        1 acatgggatt ggaactaaat atgtgcactg gtaccagcag aagccagcgc aggcccctgt
       61 gttggtcatc tatgctgata ccagacggcc ctcagggatc cctgagggat tctctggctc
      121 caactcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggt atgaggctga
      181 ctatttctgt caggtgtggg acgatagtag tgatcatccg gttttcggcg gagggacccg
      241 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004192             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:19726:19114
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004192
VERSION     KCWK01004192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19726:19114"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69930.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       411..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          155 c          119 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cgatatcttc
      241 tgagatacaa atcggactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacgcaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattatatt ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004193             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:9316:18162
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004193
VERSION     KCWK01004193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9316:18162"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69931.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       403..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          158 c          121 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca cgaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtggccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa ccggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tccggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttgttcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004194             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:20172:18929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004194
VERSION     KCWK01004194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20172:18929"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69932.1"
                     /translation="DYHCAIGHSSGLYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          158 c          120 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacgtacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca aataagggcc agggctctgg ggtccccagc cgcttctctg
      301 gatccagtaa tgcctcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgaggctga ctatcactgt gccattgggc acagcagcgg tctttacatt ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004195             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:17554:9427
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004195
VERSION     KCWK01004195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17554:9427"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69933.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          149 c          129 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004196             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:7866:4399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004196
VERSION     KCWK01004196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7866:4399"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..314
                     /note="immunoglobulin light chain variable region"
     V_region        7..314
     V_segment       7..277
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69934.1"
                     /translation="DYSCQVYDSSANVLF"
     J_segment       280..314
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           75 a          105 c           94 g           78 t
ORIGIN      
        1 acatggggga gcatcggcca gactcccctg caccctgagc agtgacctca gtgttggtag
       61 taaaaacatc tactggtacc agcagaagcc agggagcgct cccaggttat tcctgtacta
      121 ctactccgac tcagacaagc agctgggacc tggggtcccc aatcgagtct ctggctccaa
      181 ggagacctca agtaatacag cgtttttgct catctctggg ctccagcctg aggacgaggc
      241 cgattattcc tgtcaggtgt atgacagtag tgctaatgtc ttattcggag gagggacccg
      301 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004197             318 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:16155:5429
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004197
VERSION     KCWK01004197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 318)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16155:5429"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..280
                     /note="immunoglobulin light chain variable region"
     V_region        9..280
     V_segment       9..244
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>252
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69935.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       248..280
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        281..>318
                     /gene="IGLC"
BASE COUNT           70 a           89 c           96 g           63 t
ORIGIN      
        1 acatgggggg ccaggatcac ctgtggggga gacaacattg gaactaaaac tgtgcactgg
       61 taccaacaga agccaccgca gggccctgta ttggtcatct ttgctgatag tagacggccc
      121 tcagggatcc ctgagcgatt ctctggctcc aattcaggga acaccgccac cctgaccatc
      181 agcagggtcg aggccgggga tgaggctgac tattactgtc aggtgtggga cagtagtagt
      241 aaatggatat tcggcggggg gacccggcta accgtcctag gtcagcccaa ggctgccccc
      301 tcggtcactc tcttcccg
//
LOCUS       KCWK01004198             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:10757:7340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004198
VERSION     KCWK01004198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10757:7340"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69936.1"
                     /translation="DYFCAAWDDSLTGYIF"
     J_segment       413..449
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           94 a          161 c          123 g          109 t
ORIGIN      
        1 acatggggaa gcgcagcttc agctgtgggt acagaaggca ggactcagga caatctccag
       61 catggcctgg ttccctctcc tcctcaccct cctcactcac tgtgcagggt ccagggccca
      121 gtctgtgctg actcagcctc cctcagcgtc tgaggccgcc aggaagagtg tcaccatctc
      181 ctgttctgga accagctcca acatcggaag taatagtgtg tcctggtacc agcagctccc
      241 agaaacggct cccaaactcc tcatctatta taatcatcgg cgagcctcag gtgtctctga
      301 ccgattctct ggctccaagt ctggcacgtc agcctccctg gccatcagtg ggctccagac
      361 cgaggatgag gctgattatt tctgcgcagc atgggatgat agcctgaccg gttacatttt
      421 cggtcctggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      481 gttcccg
//
LOCUS       KCWK01004199             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:17846:9399
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004199
VERSION     KCWK01004199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17846:9399"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69937.1"
                     /translation="DSYCAAWDDSLTGYVF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           92 a          158 c          122 g          109 t
ORIGIN      
        1 acatggggag cctcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcctcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccgggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaatag tgtatcctgg taccaacaaa tcccagaaac
      241 ggctcccaaa ctcctcatgt attatagtca tcggcgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cttcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tcttactgcg cagcatggga tgatagcctg accggttacg tcttcggttc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01004200             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:14367:19892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004200
VERSION     KCWK01004200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14367:19892"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..403
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69938.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       408..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          155 c          121 g          110 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccccga
      121 ctcagactcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tattgggtat tatcatgctg tgtcttggta ccaacatcat ccaggcaaag
      241 cccccaaact catgatttat gaggtcaata aacggcccgc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag actgaggatg
      361 aggctgatta ttactgcagc tcatatgcag gcagcaacac tttattcttc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004201             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11425:18777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004201
VERSION     KCWK01004201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11425:18777"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69939.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          156 c          117 g          114 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacgtacac tggtatcagc tgaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc tgggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aatacaggga ttttacacat ctctggtttc cagtctgaag
      361 atgaggctga ctattactgt gccattggcc acggcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004202             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:11830:13417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004202
VERSION     KCWK01004202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11830:13417"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..403
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69940.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       407..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          156 c          122 g          109 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata atgtgtcctg gtaccagcac ctcccaggaa
      241 cagctcccaa actcctcatc tattataatg atcaacgagg ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcgtggg atgatagcct gagtagttac atcttcgctg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01004203             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:8755:6786
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004203
VERSION     KCWK01004203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:8755:6786"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69941.1"
                     /translation="DYYCQVWDSSSEWVF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           92 a          143 c          135 g           92 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca gactctgcga cctcctatga attgactcag
      121 gcaccctcag tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta aaactgtgca ctggtaccaa cagaaggcag cgcaggcccc tgtgctggtc
      241 atctttgctg atagcaaacg gccctcaggg atccctgacc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtgaatgg gttttcggcg gagggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004204             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:12814:17505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004204
VERSION     KCWK01004204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:12814:17505"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69942.1"
                     /translation="DYYCQVYDSSDVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          160 c          117 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctatgctg actcagccac
      121 cctccctgtc tgcatccccg ggaacatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatattgg taataaaaac atgtactggt accagcagaa gccagggagc gctcccaagt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgatgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004205             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:6889:6751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004205
VERSION     KCWK01004205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:6889:6751"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69943.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       397..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           81 a          155 c          126 g          107 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcatctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagcattggc aacagctatg tgtactggtt ccagcagcgg ccgggcagcg tccccactat
      241 tgtgatttac aaagatgacc aaagaccctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctgga ctgaagtctg gggacgaggc
      361 tgactattac tgtcagtctt ttgacagcag cagtgtctta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004206             342 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:13080:2571
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004206
VERSION     KCWK01004206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 342)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13080:2571"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..304
                     /note="immunoglobulin light chain variable region"
     V_region        7..304
     V_segment       7..267
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <229..>276
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69944.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       269..304
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        305..>342
                     /gene="IGLC"
BASE COUNT           70 a          109 c           89 g           74 t
ORIGIN      
        1 acatgggggg ccccagggca gagggtcacc atctcctgca ctgggagcag ctccaacatt
       61 ggaggttatt atatatcctg gtaccagcag ctcccaggaa cggcccccaa actcctcgtc
      121 tatgacaata ataagcgacc ctcaggggtt tctgaccgat tctctggctc caagtctggt
      181 tcctcagcca ccctgaccat cactgggctc cagactgagg atgaggctga ttattactgc
      241 cagtcctatg acagcagtct gagtgctcgg gtattcggcg gagggacccg gctaaccgtc
      301 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004207             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:17276:13026
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004207
VERSION     KCWK01004207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17276:13026"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69945.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcaac ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004208             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:14694:11946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004208
VERSION     KCWK01004208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14694:11946"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..330
                     /note="immunoglobulin light chain variable region"
     V_region        8..330
     V_segment       8..290
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <258..>302
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69946.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       293..330
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        331..>368
                     /gene="IGLC"
BASE COUNT           77 a          113 c           92 g           86 t
ORIGIN      
        1 acatgggcct ctcagcatct cctggagcat cagccagtct cacatgcacc ttcagcggtg
       61 gcatcaatgt tgctgactac cacgtacact ggtatcagca gaagccaggg agtccccccc
      121 ggtatcttct gaggtacaaa tcagactcag ataagggcct gggctctgga gtccccagcc
      181 gcttctctgg atccaaagat gcttcagcga atacagggat tttacacatc tctggtttcc
      241 agtctgagga tgaggctgac tattactgtg ccattggcca cggcagcggt gattacatct
      301 tcggtactgg gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      361 tgttcccg
//
LOCUS       KCWK01004209             450 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:12775:16231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004209
VERSION     KCWK01004209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12775:16231"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..412
                     /note="immunoglobulin light chain variable region"
     V_region        88..412
     V_segment       88..375
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69947.1"
                     /translation="DYYRKSWDSSGTHYIF"
     J_segment       376..412
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>450
                     /gene="IGLC"
BASE COUNT           91 a          146 c          112 g          101 t
ORIGIN      
        1 tcagaagcag aactctgggt cctctccacc atggcctgga cccctcccct gctcatcctc
       61 ctcactctct gcacaggttc cgtggtttcc tctgagctga ctcaggagcc tgcattgtct
      121 gtggccttgg gacaaacagt caggatgacc tgccaaggag acagcctcaa aacctattat
      181 gcaagctggt accagcagaa gccaggccag gtccctgtgc tggtcatcta tggtaacaac
      241 taccggccct cagggatccc aggccgattc tctgtctcct ggtcaggaaa cacaggttcc
      301 ttgaccatca ctgcggctca ggtggaagat gaggctgact attaccgtaa gtcctgggac
      361 agcagtggta cccattacat cttcggtgct gggacccggc tcaccgtcct aggtcagccc
      421 aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004210             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:15572:6127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004210
VERSION     KCWK01004210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15572:6127"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69948.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          155 c          126 g          106 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gactccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagaaata gtgtatcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagcgggctc caggccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagcggttac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01004211             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:22520:8510
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004211
VERSION     KCWK01004211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:22520:8510"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69949.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       413..448
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          162 c          126 g          107 t
ORIGIN      
        1 acatgggggg ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctcgt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cacagccgcc ctcagtgtct ggggccccag ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggaggt tattatatat cctggtacca gcagctccca
      241 ggaacggccc ccaaactcct cgtctatgac aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggttcctca gccaccctga ccatcactgg gctccagact
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtctgagtgc tcgggtattc
      421 ggcggaggga cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004212             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10673:19075
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004212
VERSION     KCWK01004212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10673:19075"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..279
                     /note="immunoglobulin light chain variable region"
     V_region        8..279
     V_segment       8..243
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69950.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       247..279
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>317
                     /gene="IGLC"
BASE COUNT           69 a           90 c           96 g           62 t
ORIGIN      
        1 acatgggggc caggatcacc tgtgggggag acgacattgg aactaaaact gtgcactggt
       61 accaacagaa gccaccgcag ggccctctat tggtcatctt tgctgatagt agacggccct
      121 cagggatccc tgagcgattc tctggctcca actcagggaa caccgccacc ctgaccatca
      181 gcagggtcga ggccggggat gaggctgact attactgtca ggtgtgggac agtagtagta
      241 aatggatatt cggcgggggg acccggctaa gcgtcctagg tcagcccaag gctgccccct
      301 cggtcactct cttcccg
//
LOCUS       KCWK01004213             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:8419:10502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004213
VERSION     KCWK01004213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:8419:10502"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69951.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          162 c          114 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcagtg
      181 ttggtactta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacca ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcaggtc tgttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004214             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13538:11795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004214
VERSION     KCWK01004214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13538:11795"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69952.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          139 c          139 g           96 t
ORIGIN      
        1 acatggggct gactttggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactttacag gctctgcggc ctcctatgag gtgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa aagtgtgcag tggtaccagc agacgccacc gcaggcccct gtactggtca
      241 tttatggtga tagggaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggatagcagt agtaaatatg tattattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004215             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:9200:10729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004215
VERSION     KCWK01004215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9200:10729"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..330
                     /note="immunoglobulin light chain variable region"
     V_region        8..330
     V_segment       8..293
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <261..>302
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69953.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       294..330
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        331..>368
                     /gene="IGLC"
BASE COUNT           77 a          113 c           97 g           81 t
ORIGIN      
        1 acatgggctc cctgtctgca tccccgggag catcggccag actcccctgc accctgagca
       61 gtgacctcag tgttggaaat aaaaacatat actggtacca gcagaagcca gggagcgctc
      121 ccaggttatt cctgtactac tactccgact cagacaagca gctgggacct ggggtcccca
      181 atcgagtctc tggctccaag gagacctcaa gtcatacagc gtttttgctc atttctgggc
      241 tccagcctga ggacgaggcc gactattact gtcaggtgta tgacgatagt gctgtgttat
      301 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      361 tcttcccg
//
LOCUS       KCWK01004216             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:28594:12225
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004216
VERSION     KCWK01004216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:28594:12225"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69954.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          159 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct ggactccagc
      361 ctgaggacga ggccgattat tattgtcagg tgtatgacga tagtgctgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004217             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:19975:10341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004217
VERSION     KCWK01004217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19975:10341"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..387
                     /note="immunoglobulin light chain variable region"
     V_region        63..387
     V_segment       63..350
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <312..>359
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69955.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       353..387
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        388..>425
                     /gene="IGLC"
BASE COUNT           80 a          129 c          123 g           93 t
ORIGIN      
        1 acatgggggc cgggaccctt ctcctcctcg gcctccttgc tcactttaca ggctctgtgg
       61 cctcctatga gttgcctcag ccacgctcag tgtccgtgtc cccaggacag acggccagga
      121 tcacctgtgg gggagacaac attggaagta atagtgtgca ttggtaccag cagaagccac
      181 cgcgggcccc tgtattggtc atctctgttg atagcgaacg gccctcaggg atccctgagc
      241 gattctctgg ttccagatca gggaacaccg ccaccctgac catcagcggg gtcgaggccg
      301 gggatgaggc tgactattac tgtcaggtgt gggataatat ttataaatac gcggtattcg
      361 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      421 tcccg
//
LOCUS       KCWK01004218             345 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:11982:20534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004218
VERSION     KCWK01004218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 345)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11982:20534"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..307
                     /note="immunoglobulin light chain variable region"
     V_region        8..307
     V_segment       8..270
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <235..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69956.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       271..307
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>345
                     /gene="IGLC"
BASE COUNT           72 a          107 c           88 g           78 t
ORIGIN      
        1 acatgggcag ccagtctcac atgcaccttc agcggtggca tcaatgttgg tgtctaccac
       61 atacactggt accaactgaa gccagggagt cccccccggt atcttctgag gtacaaatca
      121 gactcagata agggccaggg ctctggagtc cccagccgct tctctggatc cagtaatgct
      181 tcagcgaaca cagggatttt acgcatctct gggctccagt ctgaggatga ggctgactat
      241 tactgtgcca ttggacacag cagcggtcct tacatcttcg gtgctgggac ccggctcacc
      301 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004219             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:14460:3195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004219
VERSION     KCWK01004219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14460:3195"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69957.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           82 a          157 c          128 g          106 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcagcgct ctcgggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcagtct gccctgactc
      121 agcctccctc agtgtccaag tctcttggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat tggtggttat gatggcgtct cctggtacca gcagcactca gggacagccc
      241 ccagactcct gatttatgat gtcactaagc ggccctcagg ggtctcggat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctca ccatctctgg gctccagact gaggacgagg
      361 ctgattatta ctgttgctca tataggagtg gaaacacttg gctattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004220             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:12696:4948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004220
VERSION     KCWK01004220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12696:4948"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..439
                     /note="immunoglobulin light chain variable region"
     V_region        106..439
     V_segment       106..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69958.1"
                     /translation="DYYCSSYAGRNTHWLF"
     J_segment       409..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           88 a          160 c          121 g          108 t
ORIGIN      
        1 acatgggggg ggggtctcag gaggcagcgc tctcaggacg tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagcctccct ctgtgtctgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgaca tcggtggtta taactatgtc tcctggtacc aactacaccc aggcaaagcc
      241 cccaaactca tgatttatga tgtcaataag cggccctcag gggtctctga tcgcttctct
      301 ggctccaaat ctgacaacac ggcctccctg accatctctg ggctccaggc tgaggatgag
      361 actgattatt actgcagctc atatgcaggc cgcaacactc attggctttt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004221             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:22806:9974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004221
VERSION     KCWK01004221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:22806:9974"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69959.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       405..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           89 a          160 c          121 g          107 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgacccagcc aacctccctc
      121 tcagcatctc cgggagcatc agccagactc agctgcacct tgagcagtgg cgtcaatgtg
      181 ggtagttaca gcgtattctg gtaccagcag aagccaggga gtcctccccg gtaccttctg
      241 tactaccagt cagactcaag gaaacaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcagccaa tgcagggctg ttactgatct ctgggctcca gtctgaagat
      361 gaggctgact attactgtgc cctatggcac agcagcgctt cttgcatctt cggtggtggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01004222             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:21481:12677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004222
VERSION     KCWK01004222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21481:12677"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69960.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          153 c          115 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttggtaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaattacca cagagactca gatattcacc agggctctgg agtccccagc cgcttctctg
      301 ggtccaagga tgcctcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggta ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004223             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:10001:8482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004223
VERSION     KCWK01004223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10001:8482"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..431
                     /note="immunoglobulin light chain variable region"
     V_region        104..431
     V_segment       104..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69961.1"
                     /translation="DYYCSSYAGSKTLF"
     J_segment       400..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          156 c          122 g          103 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcaggacgtc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctct gtgtctgggt ctcctggaca ggcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtgcttata actatgtctc ctggtaccag cagcacccag gcaaagcccc
      241 caaactcatg atttatgatg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaaatct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caaaacgtta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004224             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:25874:19869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004224
VERSION     KCWK01004224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:25874:19869"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69962.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       392..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          139 c          138 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcaggc
      121 accctcgatt tcagtgtccc ccggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 gtatgctgat agcgagcggc cctcagggat ccctgggcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacatgaata gtcatcatct attattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004225             411 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:4750:13902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004225
VERSION     KCWK01004225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 411)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4750:13902"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..373
                     /note="immunoglobulin light chain variable region"
     V_region        89..373
     V_segment       89..336
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <298..>345
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69963.1"
                     /translation="DYYCQVWDSSSDHVFF"
     J_segment       337..373
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        374..>411
                     /gene="IGLC"
BASE COUNT           82 a          127 c          122 g           80 t
ORIGIN      
        1 acatggggct gggcctcagg aagcagcctt ggcggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggacagacgg ccaggatcac ctgtggggga
      121 gacaacatta gaagtaaaaa tgtgaattgg taccagcaga agccaccgca ggcccccgcg
      181 ctggtcatct attatgatag cgaccggccc tcagggatcc ctgagcgatt ctctggctcc
      241 aactcaggga acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac
      301 tattactgtc aggtgtggga cagtagtagt gatcatgtgt ttttcggagg agggacccgg
      361 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004226             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:14079:14945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004226
VERSION     KCWK01004226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14079:14945"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..264
                     /note="immunoglobulin light chain variable region"
     V_region        8..264
     V_segment       8..227
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <192..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69964.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       228..264
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>302
                     /gene="IGLC"
BASE COUNT           68 a           97 c           70 g           67 t
ORIGIN      
        1 acatgggtgc ctaccacata cactggtacc agcagaagcc agggagtccc ccccggtatc
       61 ttctgactta caaatcagac tcagataagg gccagggctc tggagtcccc agccacttct
      121 ctggatccaa aaatgcttca acaaacacag gcattttaca catctctggg ctccagtctg
      181 aggatgaggc tgactatttc tgtgccattg gacacagcag cggtccttac atcttcggtg
      241 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      301 cg
//
LOCUS       KCWK01004227             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:18283:15317
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004227
VERSION     KCWK01004227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18283:15317"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..411
                     /note="immunoglobulin light chain variable region"
     V_region        81..411
     V_segment       81..374
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69965.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       375..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           87 a          148 c          112 g          102 t
ORIGIN      
        1 acatggggag gacaatctcc agcatggcct ggttccctct cgtcctcacc ctcctcactc
       61 actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc tccctcagcg tctgaggccg
      121 ccaggaagag tgtcaccatc tcctgttctg gaagcagctc caacatcgga agtaataatg
      181 tgtcctggta ccagcacctc ccaggaacag ctcccaaact cctcatctat tataatgatc
      241 aacgaggctc aggtgtctct gaccgattct ctggctccaa gtctggcacg tcagcctccc
      301 tggccatcag tgggctccag accgaggatg aggctgatta ttactgcgca gcgtgggatg
      361 ataggctgag cagttacatc ttcgctgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004228             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:20819:20343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004228
VERSION     KCWK01004228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20819:20343"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69966.1"
                     /translation="DYYCQVYDSSAHVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          162 c          123 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg acgcagccac
      121 cctccctgtc tgcatccccg ggagcaccgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tactaaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tatttctgta ttacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt ggtcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tctatgacag tagtgctcat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004229             345 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:14919:4901
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004229
VERSION     KCWK01004229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 345)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14919:4901"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..307
                     /note="immunoglobulin light chain variable region"
     V_region        8..307
     V_segment       8..270
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <226..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69967.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       271..307
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>345
                     /gene="IGLC"
BASE COUNT           72 a          103 c          102 g           68 t
ORIGIN      
        1 acatgggcgg tgtccccagg acagacagcc agcatcacct gctctggaaa taaattgggg
       61 aatgtatatg cttactggtt ccagcagaag ccaggccagg cccctgtagt ggtcatctac
      121 aaagatacca accggccctc agggatccct gagcgattct ctggctccga ctcagggaac
      181 acggccaccc tgaccatcag cagggtcgag gctggggatg aggccgacta tttttgtgct
      241 gcagcctatg gcagtggcag cagctggcag tgggtattcg gcggagggac ccggctaatc
      301 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004230             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15423:18393
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004230
VERSION     KCWK01004230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15423:18393"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..329
                     /note="immunoglobulin light chain variable region"
     V_region        8..329
     V_segment       8..292
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <255..>302
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69968.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       294..329
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        330..>368
                     /gene="IGLC"
BASE COUNT           80 a          112 c          102 g           74 t
ORIGIN      
        1 acatgggcta tgatctgact cagccaccct cggtgtcagt gtccccagga cagacggcca
       61 ggatcacctg tgggggagac aacattggaa gtcaaagtgt gcactggtac cagcacaagc
      121 caccgcaggc ccctgttctg gtcatctttt attataccga acggccctca ggaatccctg
      181 agcgaatctc tggctccaaa tcagggaaca ccgccaccct gaccatcagc ggggtcgagg
      241 ccggggatga ggctgactat tactgtcagg tgtgggacac aagtcttgat cacggcttat
      301 ttggaggagg gacccggctg accgtcctaa gtcagcccaa ggctgccccc tcggtcactc
      361 tcttcccg
//
LOCUS       KCWK01004231             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:16039:16067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004231
VERSION     KCWK01004231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:16039:16067"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69969.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       407..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          154 c          131 g          112 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggttacc atctcctgca
      181 ctgggagcag ctccaacatc ggggcgggtt tttatgtgtc ctggtaccag cagttccctg
      241 gaacagcccc caaactcctc atctttgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgctcatcat gggaaagcag cctgaattgg gttttcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004232             349 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:11061:3025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004232
VERSION     KCWK01004232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 349)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11061:3025"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..311
                     /note="immunoglobulin light chain variable region"
     V_region        7..311
     V_segment       7..272
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>283
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69970.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       274..311
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        312..>349
                     /gene="IGLC"
BASE COUNT           72 a          105 c           94 g           78 t
ORIGIN      
        1 acatggggga gcatcggcca gactcccctg caccctgagc agtgacctca gtgttggtag
       61 taaaaacatg tactggtacc agcagaagcc agggagcgct cccaggttat tcctgtacta
      121 ctactccgac tcagacaacc agctgggacc tggggtcccc aatcgagtct ctggctccaa
      181 ggagacctca agtaacacag cgtttttgct catctctggg ctccagcctg aggacgaggc
      241 cgattatttc tgccaggtgt ttgacagtag tgttgtgttc ttcggaggag ggacccgact
      301 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004233             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:25492:11473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004233
VERSION     KCWK01004233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25492:11473"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69971.1"
                     /translation="DSNCWSTDSSGNWVF"
     J_segment       372..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           93 a          139 c          120 g           94 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tagcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtccg
      121 tgtccccagg acagacggcc aggatcacct actatggaga cgcacagcca aaaagatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtggt gatcatttat gaggacatca
      241 aacggccctc tggcatccct gagagattct ctggcgccaa ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg gagctgactc caattgttgg tcaacagaca
      361 gcagtgggaa ttgggtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004234             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:19141:3279
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004234
VERSION     KCWK01004234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19141:3279"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69972.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          160 c          112 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgagtctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004235             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:18308:15377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004235
VERSION     KCWK01004235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18308:15377"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69973.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          161 c          112 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgttgccta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagttacga atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaaa tgcttcaaca aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004236             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:10948:19144
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004236
VERSION     KCWK01004236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10948:19144"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69974.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           82 a          163 c          122 g          101 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtggccac
      181 tacagctaca ccatcgcatg gcatcagcag cagcaaggga aggcccctcg gttcttgatg
      241 tggcttaaga gtgatggcag ccacaccaag ggggacgggg tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatattggc atttgggtat tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004237             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:10063:11681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004237
VERSION     KCWK01004237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10063:11681"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69975.1"
                     /translation="DYFCAAWDDSLTGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           92 a          158 c          121 g          110 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcctcctca ccctcctcac tcactgtgca gggtccaggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggatccagc tccaacatcg gaagtaatag tgtgtcctgg taccagcagc tcccagaaac
      241 ggctcccaaa ctcctcatct attataatca tcggcgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tatttctgcg cagcatggga tgatagcctg accggttaca ttttcggtac
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01004238             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:3748:12127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004238
VERSION     KCWK01004238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:3748:12127"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..390
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69976.1"
                     /translation="DYYCSSWESSLNWIF"
     J_segment       392..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          149 c          126 g          104 t
ORIGIN      
        1 acatgggggg ggcacaggag gcagcactca ggacagtctc cagcatggcc tggtctctcc
       61 ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg acgcagccgc
      121 cctcagcatc tggggccccc gggcagaggg ttaccatctc ctgcactggg agcagctcca
      181 acatcggggc gggtttttat gtgtcctggt accaacagtt ccctggaaca gcccccaaac
      241 tcctcatcta tgaaaataat aagcgaccct caggggtttc tgaccgattc tctggctcca
      301 agtctggttc ctcagcctcc ctgaccatca ctggactcca gtctgaggat gaggctgatt
      361 attactgctc atcatgggaa agcagcctga attggatatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004239             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:26317:16388
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004239
VERSION     KCWK01004239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:26317:16388"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..237
                     /note="immunoglobulin light chain variable region"
     V_region        115..237
     V_segment       115..199
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <162..>209
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69977.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       201..237
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>275
                     /gene="IGLC"
BASE COUNT           44 a           89 c           81 g           61 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac tgtcaggtgt
      181 gggacacaac tattgatcac ggcttgttcg gaggagggac ccggctgacc gtcctaggtc
      241 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004240             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20257:19322
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004240
VERSION     KCWK01004240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20257:19322"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69978.1"
                     /translation="EYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          158 c          120 g          104 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtgggcac
      181 tatagttata ccatcgcatg gcatcaacaa tatcaaggga aggcccctcg gttcttgatg
      241 tggcttaaaa gtgatggcag ccacaccaag ggggacggga tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctctcc atctccaacc tccagtctga ggatgaggct
      361 gagtattact gtcagacctg ggacattggc atttgggtat tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004241             336 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:7152:10145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004241
VERSION     KCWK01004241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 336)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7152:10145"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..294
                     /note="immunoglobulin light chain variable region"
     V_region        8..294
     V_segment       8..261
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <217..>270
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69979.1"
                     /translation="DYHCSAGFGSGYSWQWVF"
     J_segment       262..294
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>336
                     /gene="IGLC"
BASE COUNT           72 a           98 c           98 g           68 t
ORIGIN      
        1 acatgggcag gacagacagc cagcatcacc tgctctggag ataaattggg gaatgtttat
       61 gcttattggt accagcagaa gccaggccag gcccctatac tggtcatcta caaagatagc
      121 aaccggccct cagggatccc tgaccgattc tctggctcca actcagggaa cacggccacc
      181 ctgaccatca gcagggtcga ggctggggat gaggccgact atcactgttc tgcaggcttt
      241 ggtagtgggt acagctggca gtgggttttc ggcggaggga cccggctaac cgtcgtaggt
      301 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004242             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11389:9971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004242
VERSION     KCWK01004242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11389:9971"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..376
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69980.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       388..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          145 c          131 g           96 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctttgagt tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaattaaa tttgtccact ggtaccagca gaagccagcg caggcccctg tgaaggtcat
      241 ctatgctgat gacaaacggc cctcagggat ccctgagaga ttctctggct ccaattcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattcctg
      361 tcaggtgtgg gacagtgaga ctgattatta catcttcggt actgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004243             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:16265:7650
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004243
VERSION     KCWK01004243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16265:7650"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69981.1"
                     /translation="DYYCQVYDSNAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          166 c          118 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cccctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg cagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctcta ctactactcc gactcagaca accaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgccagg tgtatgacag taatgctgtt ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004244             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:22367:8935
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004244
VERSION     KCWK01004244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22367:8935"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..391
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69982.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       396..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          153 c          121 g          102 t
ORIGIN      
        1 acatggggga cagaaggcag gactcaggat aatctccagc atggcctggt tccctctcgt
       61 cctcaccctc ctcactcact gtgcagggtc ctgggcccag tctgagctga ctcagccacc
      121 ctcagcgtct ggggctcccg ggcagagtgt caccatctcc tgctctggaa gcagctccaa
      181 tattggaagt aattctgtat actggtacca gcagttccca ggaacggccc ccaaactcct
      241 catctattat agtaatcagc gaccctcagg ggtccctgac cgagtctctg gctctaagtc
      301 gggcacctca gcctccctgg ccatcactgg tctccgatct gaggatgagg ctgattatta
      361 ctgtgcagca tgggatgaca gcctgagaag tccgctattc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004245             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:5413:8987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004245
VERSION     KCWK01004245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5413:8987"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69983.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           90 a          154 c          120 g          109 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgcg ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc agtggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcgtcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgaag
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt attcttcgga cgagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004246             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:23386:11706
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004246
VERSION     KCWK01004246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23386:11706"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..213
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69984.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       219..251
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           58 a           85 c           91 g           55 t
ORIGIN      
        1 acatggggga agtgaagttg tgaactggta ccagcagaag ccagcgcagg cccctgtgct
       61 ggtcatctat gctgatagcg aacggccctc agggatccct gagcgattct ctggctccaa
      121 atcagggaac acggccaccc tgaccatcag cggggtcgag gccgggggtg aggctgacta
      181 ttactgtcag gtgtgggaca tgcgtagtga tcaaccgcta ttcggcggag ggacccggct
      241 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004247             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:5455:12348
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004247
VERSION     KCWK01004247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:5455:12348"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..434
                     /note="immunoglobulin light chain variable region"
     V_region        89..434
     V_segment       89..397
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69985.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       398..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           91 a          159 c          112 g          110 t
ORIGIN      
        1 actgggggca gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccca gcctgtgctg acccagccaa cctccctctc
      121 agcatctccg ggagcatcag ccagactcag ctgcaccttg agcagtggca atgttggtag
      181 ttacagcata ttctggtacc agcagaagcc agggagtcct ccccggtacc ttctttacta
      241 ctactcagac tcaagtaacc accaggactc tggagtcccc agccgcttct ctggatcgaa
      301 agatgcttca gccaatgcag ggcttttact gatctctggg ctccagtctg aagatgaggc
      361 tgactattac tgtgccacat ggcacagcag cgcttcttac atcttcggtg gtgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01004248             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:23284:9825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004248
VERSION     KCWK01004248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23284:9825"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69986.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           91 a          153 c          120 g          109 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat aatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaagacg gcctccctga ccatctctgg actccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacgcttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004249             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:5551:16381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004249
VERSION     KCWK01004249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:5551:16381"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69987.1"
                     /translation="DYYSQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          148 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtacact ggtaccagca caagccaccg caggcccctg ttctgctcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattacag
      361 tcaggtgtgg gacacaacta ttgatcacgg cttgttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004250             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18669:6657
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004250
VERSION     KCWK01004250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18669:6657"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69988.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          160 c          112 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004251             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:20013:15040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004251
VERSION     KCWK01004251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20013:15040"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69989.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          147 c          129 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgtcccctcg gtcactctct tcccg
//
LOCUS       KCWK01004252             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:18578:17401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004252
VERSION     KCWK01004252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18578:17401"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..398
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69990.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           88 a          151 c          122 g          110 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 actccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgatattg ggtattatca tgctgtgtct tggtaccagc atcatccagg caaagccccc
      241 aaactcatga tttatgaggt caataaacgg cccgcagggg tctctggtcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 gattattact gcagctcata tggaggcagc aatagtttat tcttcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004253             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:17886:13863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004253
VERSION     KCWK01004253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:17886:13863"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..404
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69991.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       406..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           86 a          163 c          121 g          111 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt agtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt tctgccagct gtttgacagt agtgttgtgt tcttcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01004254             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:13656:10992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004254
VERSION     KCWK01004254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13656:10992"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69992.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           89 a          143 c          126 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004255             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:6891:4857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004255
VERSION     KCWK01004255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6891:4857"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..258
                     /note="immunoglobulin light chain variable region"
     V_region        8..258
     V_segment       8..221
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <183..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69993.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       222..258
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           64 a           88 c           82 g           62 t
ORIGIN      
        1 acatgggcaa cattggaatt aaatttgtcc actggtacca gcagaagcca gcgcaggccc
       61 ctgtgaaggt catctatgct gatgacaaac ggccctcagg gatccctgag agattctctg
      121 gctccaattc agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg
      181 ctgactattc ctgtcaggtg tgggacagtg agactgatca ttacatcttc ggtgctggga
      241 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004256             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:10197:13768
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004256
VERSION     KCWK01004256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:10197:13768"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69994.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       385..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           97 a          143 c          120 g           98 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gaagaattgc
      181 caaaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtc cagatcatct
      241 atgaggacag taaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc actggggccc aggtggagga tgaagctgac tactactgtt
      361 tctcaacaga caccagtggt aatcgggtat tcggcggagg gacccgtcta accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004257             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:25458:11177
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004257
VERSION     KCWK01004257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:25458:11177"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69995.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       414..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          157 c          122 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca accgccctca gcatctgggg cccccggaca gagggtcacc atctcctgca
      181 ttagcagcag ctccaacatc ggggcggctt attatgtatc ctggtaccaa cagttcccag
      241 gaacagcccc caaactcctc atctttgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtccctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattac tgtttagcat gggataccag cctgaattgg atcttcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004258             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:27087:14657
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004258
VERSION     KCWK01004258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:27087:14657"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69996.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          147 c          131 g           95 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atcgctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004259             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:16380:10396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004259
VERSION     KCWK01004259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16380:10396"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69997.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          156 c          121 g          111 t
ORIGIN      
        1 acatgggggc agcctcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgttgactc agcctccctc agcgtctgag gccgccggga agagtgtcac catctcctgt
      181 tctggaagca gttccaacat cggaagtaat agtgtatcct ggtaccaaca actcccagaa
      241 acggctccca aactcctcat gtattataat catcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacttcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagtatgg gatgatagcc tgaccggtta catcttcggt
      421 actgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004260             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:19732:8083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004260
VERSION     KCWK01004260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19732:8083"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69998.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          155 c          116 g          114 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaagctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctgggca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtcttata atgctgtgtc ttggtaccaa caacatccag gcaaagcccc
      241 ccaactcata atttttgagg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catttctggg ctccaggctg aggatgaggc
      361 tgattattac tgctgctcat atgtaggcag caacacttac atcttcgatg ttgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01004261             408 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:16702:12745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004261
VERSION     KCWK01004261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 408)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16702:12745"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    77..370
                     /note="immunoglobulin light chain variable region"
     V_region        77..370
     V_segment       77..326
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <298..>342
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV69999.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       333..370
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        371..>408
                     /gene="IGLC"
BASE COUNT           79 a          130 c           98 g          101 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tggacagtcg gtcaccatct cctgcactgg aaccagcagt
      121 aatattgggt cttataatgc tgtgtcttgg taccaacagc atccaggcaa agccccccaa
      181 ctcataattt ttgaggtcaa taagcggccc tcaggggtct ctgatcgctt ctctggctcc
      241 aagtctggca acacggcctc cctgaccatc tctgggctcc aggctgagga tgaggctgat
      301 tattactgct gctcatatgt aggcagcaac acttacatct tcgattttgg gacccggctc
      361 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01004262             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12282:15360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004262
VERSION     KCWK01004262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12282:15360"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70000.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          161 c          115 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctctgcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcagactca gataaggacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcctcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctactactgt gccattgggc acagcagcgg tgattacatt ttcgctgctg
      421 ggacccgcct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004263             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:12653:9897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004263
VERSION     KCWK01004263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12653:9897"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70001.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           90 a          143 c          126 g          102 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc catcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacagc cggccaggat cacctgctct ggagatgtat
      181 tgccaaaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtattggtca
      241 tctctgagga caccaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttactcagc agacagtagt ggtcatggct tcttcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004264             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:18247:15122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004264
VERSION     KCWK01004264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18247:15122"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70002.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          159 c          113 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtact gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc atcaatgttg
      181 gtagttacag cgtattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc tggggtccag tctgaggatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc ggtactggga
      421 cccggttcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004265             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:20310:7969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004265
VERSION     KCWK01004265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20310:7969"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70003.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          147 c          131 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgggcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004266             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:7776:8096
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004266
VERSION     KCWK01004266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7776:8096"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..389
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70004.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       394..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          158 c          118 g          102 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcccccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctcccagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggacgatag cctgcgcggc tatatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004267             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:23501:4929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004267
VERSION     KCWK01004267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23501:4929"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70005.1"
                     /translation="DYHCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          163 c          124 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctacttctcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttctt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004268             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:13559:7880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004268
VERSION     KCWK01004268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13559:7880"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70006.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          162 c          111 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaagga tgcttcggcc aatgcaggcc ttttagtgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004269             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:18300:14074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004269
VERSION     KCWK01004269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18300:14074"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70007.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          160 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac ttatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacga tagtgctgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004270             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:10100:19654
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004270
VERSION     KCWK01004270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10100:19654"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..396
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70008.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       398..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           95 a          151 c          115 g          110 t
ORIGIN      
        1 acatggggtc tggagccagg gatcccttcc aatatcagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcacctgtgc ttccagcact
      181 ggagcagtca ccagtggtca ctctccacac tggttccaac agaaacctgg acaagccccc
      241 aagacactga tttataatac aaactacaga cactcctgga ctcctgcccg gttctcaggc
      301 tccctccttg ggggtaaagc tgccctgaca ctgtcaggtg cgcagcctga ggatgaggct
      361 gagtattatt gtttactgta ctatagtggt gctcagctgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004271             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10039:8119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004271
VERSION     KCWK01004271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10039:8119"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..395
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70009.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       396..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           87 a          157 c          120 g          105 t
ORIGIN      
        1 acatgggggt ctcaggaggc agcgctctcg ggacatctcc accatggcct gggctctgct
       61 cctcctcacc ctcctcactc agggcacagg atcctgggct caggctgccc tgactcagcc
      121 tcgctcagtg tctgggtctc ctggacagtc ggtcaccatc tcctgcactg gaaccagcag
      181 tgacatcggt ggttataact atgtctcctg gtaccaacag catccaggca cagcccccaa
      241 agtcatgatt tatgaggtca gtaagcggcc ctcaggggtc tctgatcgct tctctggctc
      301 caagtctggc aacacggcct ccctgaccat ctctgggctc caggctgagg acgaggctga
      361 ttattactgc agctcatata caggcatcaa cagttacatc ttcggtggtg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004272             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:13650:7721
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004272
VERSION     KCWK01004272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13650:7721"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..433
                     /note="immunoglobulin light chain variable region"
     V_region        106..433
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70010.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       397..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           92 a          143 c          132 g          104 t
ORIGIN      
        1 acatggggag cctgggcctc aggaggcagc attgacggtg cctcagccat ggcctggact
       61 tttctcctcc tcggcctcct tgcttactgc acagtctctg cggcctccta tgatctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tggaggagac
      181 aacattggaa gtgaagttgt caactggtac cagcagaagc caccgcaggc ccctgtgctg
      241 gtcatctatg ctgattatga acggccctca gggatccctg agcgattctc tggctccaaa
      301 tcagggaaca cggccaccct gaccatcatc ggaatcgagg ccggggatga ggctgactat
      361 tattgtcagg tgtgggacat ttatattgac catccggtgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004273             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:5554:13718
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004273
VERSION     KCWK01004273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5554:13718"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70011.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          162 c          124 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaacg cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004274             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:9161:4582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004274
VERSION     KCWK01004274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9161:4582"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70012.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          157 c          120 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaggtcagg gagtcctccc cggtatcttc
      241 taagatacaa atcagactca gatcagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacgggga ttttacacgt ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004275             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:28905:8576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004275
VERSION     KCWK01004275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:28905:8576"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..266
                     /note="immunoglobulin light chain variable region"
     V_region        8..266
     V_segment       8..229
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70013.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       232..266
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           62 a           88 c           93 g           61 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaagtaa ctatgtgcac tggtaccagc agaagccagc
       61 gcaggcccct gtagagatta tctttgctga taacaaacgg ccctcaggga tccctgagcg
      121 attctctggc tccaactcag ggatcaccgc caccctgacc atcagcgggg tcgaggccgg
      181 ggatgaggct gactatttct gtcaggtgtg gggcagtcgt agtgatcatc cggtattcgg
      241 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      301 cccg
//
LOCUS       KCWK01004276             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:21335:19883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004276
VERSION     KCWK01004276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21335:19883"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..397
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70014.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       399..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           85 a          154 c          119 g          112 t
ORIGIN      
        1 acatggggga tctcaggagg cagcgctctc aggacttctc caccatggtc tgggctctgc
       61 tcctcctcac cctcctcact cagggcacag gatcctgggt tcaggctgcc ccgactcagc
      121 ctccctctgt gtccgggtct cctggacagt cggtcaccat ctcctgcact ggaacgagca
      181 gtgatattgg ctattataac gctgtgtctt ggtaccaaca gcatccaggc aaagccccca
      241 aactcatcat ttttgacgtc attaagcggc cctcaggggt ctctgatcgc ttcgctgcct
      301 ccaagtctgg cgacacggcc tccctgacca tctctgggct ccgggctgag gatgaggctg
      361 attattactg cagctcatat gccggcagaa ataatttttt attcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004277             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:13820:15747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004277
VERSION     KCWK01004277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13820:15747"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70015.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          152 c          120 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag caagtcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctctcagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgaggggt tacatcttcg gtgctgggac ccggctcgcc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004278             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:24495:10202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004278
VERSION     KCWK01004278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24495:10202"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..385
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70016.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       394..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          150 c          137 g           93 t
ORIGIN      
        1 acatgggggc tgggtctcag gaggcagcat tgacggtgcc tcagccatgg cctggaccct
       61 tctcctcctc ggcctcctcg ctcactgcac aggctctgcg acctcctatg agctgactca
      121 gccaccctcg gtgtcagcgg cctcaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaact aaatatgtgc actggtacca gcagaagcca gcgcaggccc ctgtgttggt
      241 catctatgct gataccagac ggccctcagg gatccctgag cgattctctg gctccaactc
      301 cgggaacacc gccaccctga ccatcagcgg ggtcgaggcc gggtatgagg ctgactattt
      361 ctgtcaggtg tgggacgata gtagtgatca tccggtattc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004279             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:20184:16522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004279
VERSION     KCWK01004279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20184:16522"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..434
                     /note="immunoglobulin light chain variable region"
     V_region        110..434
     V_segment       110..391
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70017.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       400..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          153 c          138 g           95 t
ORIGIN      
        1 acatgggggc cctgtctggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggcc tcctcgctca ctgcacaggc tctgcgacct cctatgagct
      121 gactcagcca ccctcggtgt cagcggcctc aggacagacg gccaggatcc cctgtggggg
      181 agacaacatt ggaactaaat atgtgcactg gtaccagcag aagccagcgc aggcccctgt
      241 gttggtcatc tatgctgata ccagacggcc ctcagggatc cctgagcgat tctctggctc
      301 caactcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggt atgaggctga
      361 ctatttctgt caggtgtggg acgatagtag tgatcatccg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004280             271 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:26205:7794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004280
VERSION     KCWK01004280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 271)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 271)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..271
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:26205:7794"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..233
                     /note="immunoglobulin light chain variable region"
     V_region        7..233
     V_segment       7..196
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <164..>205
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70018.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       197..233
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        234..>271
                     /gene="IGLC"
BASE COUNT           54 a           82 c           73 g           62 t
ORIGIN      
        1 acatgggaag ccagggagcg ctcccaggtt attcctgtac tactactccg actcagacaa
       61 gcagctggga cctggggtcc ccaatcgagt ctctggctcc aaggagacct caactaacac
      121 agcgtttttg ctcatctctg ggctccagcc tgaggacgag gccgattatt actgtcaggt
      181 gtttgacagt agtgctgtgt tattcggagg agggacccga ctgaccgtcc taggtcagcc
      241 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004281             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:20177:9807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004281
VERSION     KCWK01004281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20177:9807"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..226
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70019.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       227..263
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           60 a           92 c           87 g           62 t
ORIGIN      
        1 acatgggggg cacagcagct acaccatcgc atggcatcag catcagcaag ggaaggcccc
       61 ccggtacttg atgtggctta aaagtgatgg cagccatagc ccgggggacg ggatccctga
      121 tcgcttttca ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc
      181 tgaggatgag gctgattatt actgtcagac ctgggatact gacattgtgt tgttcggagg
      241 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01004282             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:5509:13648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004282
VERSION     KCWK01004282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:5509:13648"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70020.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       394..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          155 c          121 g          104 t
ORIGIN      
        1 acatgggggg tacagaaggc aggactcagg acaatctcca gcatggcctg gttccctctc
       61 gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc agtctgtgct gactcagcct
      121 ccctcagcgt ctgaggccgc caggaagagt gtctccatct cctgttcggg aagcagctcc
      181 aacatcggaa gtcatagtgt ctcctggtac cagcaactcc caggaacagc tcccaaactc
      241 ctcatctatt atagtgatca acgagcctca ggtgtctctg accgattctc tggctcccag
      301 tctggcacgt cagcctccct ggccatcagt gggctccaga ccgaggatga ggctgattat
      361 tactgcgcgg catgggatga tagcctgagc ggttacatct tcggtgctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01004283             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14431:10798
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004283
VERSION     KCWK01004283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14431:10798"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70021.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcaggggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004284             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:10342:18219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004284
VERSION     KCWK01004284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10342:18219"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70022.1"
                     /translation="DYYCQVYDSSANVVF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          163 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaag atgtactggt accagcagaa gccagggacc gctcccaggt
      241 tatacctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagccttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtggtattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004285             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:10822:9969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004285
VERSION     KCWK01004285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10822:9969"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70023.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          147 c          129 g           98 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtacac tggtaccagc acaagccacc gcaggcccct gttctggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttgttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004286             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:23580:7563
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004286
VERSION     KCWK01004286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:23580:7563"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70024.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       396..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          156 c          121 g          102 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct cgtctcctct
       61 cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc tgacacagcc
      121 gccctcagtg tctggggccc cagggcagag ggtcaccatc tcctgcactg ggagcagctc
      181 caacattgga ggttattata tatcctggta ccagcagctc ccaggaacgg cccccaaact
      241 cctcgtctat gacaataata agcgaccctc aggggtttct gatcgattct ctggctccaa
      301 gtctggttcc tcagccaccc tgaccatcac tgggctccag actgaggatg aggctgatta
      361 ttactgccag tcctatgaca gcagtctgag tgctcgggta ttcggcggag ggacccggct
      421 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004287             490 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:20131:16336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004287
VERSION     KCWK01004287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 490)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20131:16336"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..452
                     /note="immunoglobulin light chain variable region"
     V_region        122..452
     V_segment       122..416
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>424
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70025.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       417..452
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>490
                     /gene="IGLC"
BASE COUNT           88 a          161 c          133 g          108 t
ORIGIN      
        1 acatgggcaa cgcagagtac atgggggggg tctcaggagg cagcgctctc gggacgtctc
       61 caccatggcc tgggctctgc tcctcctcac cctcctcact cagggcacag gatcctgggc
      121 tcagtctgcc ctgactcagc ctccctcagt gtccaagtct cttggacagt cggtcaccat
      181 ctcctgcact ggaaccagca gtgacattgg tggttatgat ggcgtctcct ggtaccagca
      241 gcactcaggg acagccccca gactcctgat ttatgatgtc actaagcggc cctcaggggt
      301 ctcggatcgc ttctctggct ccaagtctgg caacacggcc tccctcacca tctctgggct
      361 ccagactgag gacgaggctg attattactg ttgctcatat aggagtggaa acacttggct
      421 attcggcgga gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac
      481 tctcttcccg
//
LOCUS       KCWK01004288             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:19394:9888
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004288
VERSION     KCWK01004288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19394:9888"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70026.1"
                     /translation="AYYCQVWDSDSDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          149 c          130 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaagccac cgcaggcccc tatgcaggtc
      241 atctatgctg ataacaaacg gccctcaggg atccctgaga gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctattac
      361 tgtcaggtgt gggacagtga tagtgatcat tacatcttcg gtggtgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004289             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:14788:15441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004289
VERSION     KCWK01004289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14788:15441"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70027.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           91 a          139 c          134 g          104 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggaaag acggccagga tcacctgtgg gggagacaat
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tattgatcat ccggtattat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004290             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:23949:14847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004290
VERSION     KCWK01004290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23949:14847"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..268
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70028.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       270..306
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           74 a          108 c           84 g           78 t
ORIGIN      
        1 acatgggtga ggccgccagg aagagtgtca ccatctcctg ttctggaagc acctccaaca
       61 tcggaagcaa taatgtatcc tggtaccagc agctcccagg aacagctccc aaactcctct
      121 tttattataa tgatcaacga gcctcaggtg tctctgaccg attctcttgc tccaagtctg
      181 gcacgtcagc ctccctggcc atcagtgggc tccagaccga ggatgaggct gattattact
      241 gcgcagcatg ggatgataac ctgagcggct acatcttcgg tgctgggacc cggctcaccg
      301 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004291             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:26506:7772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004291
VERSION     KCWK01004291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:26506:7772"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..433
                     /note="immunoglobulin light chain variable region"
     V_region        85..433
     V_segment       85..396
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70029.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           91 a          158 c          115 g          107 t
ORIGIN      
        1 acatggggaa aagaggctgt gtccaccatg gcctggactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctccaagcca atgctgactc agccggcctc cctctcagca
      121 tctcctggag catcagccag tctcacatgc accttcagcg gtggcatcag tgttgttgac
      181 taccacatac actggtacca gcagaagcca gggagtcccc cccggtttct tctgaggtac
      241 aaatcagact cagataaggg ccagggctct ggagtcccca gccgcttctc tggatccaaa
      301 gatgctgcag cgaacacagg gattttacgc atctctgggc tccagtctga ggatgaggct
      361 gactattact gtgccattgg gcacagcagc ggtccttact tcttcggtgc tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01004292             397 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:15667:10876
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004292
VERSION     KCWK01004292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 397)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15667:10876"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..359
                     /note="immunoglobulin light chain variable region"
     V_region        14..359
     V_segment       14..320
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <290..>331
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70030.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       322..359
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        360..>397
                     /gene="IGLC"
BASE COUNT           77 a          129 c          102 g           89 t
ORIGIN      
        1 acatgggctc tcccagcctg tgctgactca gccaccctcc ctgtctgcat ccccgggagc
       61 atcggccaga ctcccctgca ccctgagcag tgacctcagt gttggtagta aaaacatgta
      121 ctggtaccag cagaagccag ggagcgctcc caggttattc ctgtactact actccgactc
      181 agacaagcag ctgggacctg gggtccccaa tcgagtctct ggctccaagg agacctcaag
      241 taacacagcg tttttgctca tctctgggct ccagcctgag gacgaggccg attatttctg
      301 ccagctgttt gacagtagtg ttgtgttctt cggaggaggg acccgactga ccgtcctagg
      361 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004293             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:15970:5648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004293
VERSION     KCWK01004293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15970:5648"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70031.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          142 c          134 g          102 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtgctggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004294             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:12167:17566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004294
VERSION     KCWK01004294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12167:17566"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70032.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           89 a          155 c          126 g          110 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggtacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcagc ctccctcagc gtctgaggcc gccaggaaga gtgtctccat ctcctgttct
      181 ggaagcagct ccaacatcgg aagtcatagt gtctcctggt accagcaagt cccaggaaca
      241 gctcccaaac tcctcatcta ttatagtgat caacgagcct caggtgtctc tgaccgattc
      301 tctggctctc agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat
      361 gaggctgatt attactgcgc agcatgggat gatagcctga ggggttacat cttcggtgct
      421 gggacccggc tcgccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004295             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:9484:4477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004295
VERSION     KCWK01004295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9484:4477"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70033.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       394..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           91 a          149 c          121 g          107 t
ORIGIN      
        1 acatggggag ctgtgggctc agaagcagaa ctctgggtcc tctccaccat ggcctggacc
       61 cctcccctgc tcatcctcct cactctctgc acaggttccg tggtttcctc tgagctgact
      121 caggagcctg cattgtctgt ggccttgggc catacagtca ggatgacctg ccaaggagac
      181 agcctcaaaa cctattatgc aacctggtac cagcagaagc caggccaggt ccctgtgctg
      241 gtcatctatg gtaacaacta ccggccctca gggatcccag gccgattctc tgtctcctgg
      301 tcaggagaca caggttcctt gaccatcact gcggctcagg tggaagatga ggctgactat
      361 tattgtaagt cctgggacag cagtggtacc cattacatct tcggtgctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01004296             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:7287:13534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004296
VERSION     KCWK01004296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:7287:13534"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..411
                     /note="immunoglobulin light chain variable region"
     V_region        81..411
     V_segment       81..374
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70034.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       375..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           87 a          149 c          111 g          102 t
ORIGIN      
        1 acatggggag gacaatctcc agcatggcct ggttccctct cgtcctcacc ctcctcactc
       61 actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc tccctcagcg tctgaggccg
      121 ccaggaagag tgtcaccatc tcctgttctg gaagcagctc caacatcgga agtaataatg
      181 tgtcctggta ccagcacctc ccaggaacag ctcccaaact cctcatctat tataatgatc
      241 aacgaggctc aggtgtctct gaccgattct ctggctccaa gtctggcacg tcagcctccc
      301 tggccatcag tgggctccag accgaggatg aggctgatta ttactgcgca gcgtgggatg
      361 atagcctgag cagttacatc ttcgctgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004297             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:22220:2003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004297
VERSION     KCWK01004297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22220:2003"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..388
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70035.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       389..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           90 a          141 c          126 g          101 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagagctct ggggtgtctc caccatggcc tggactcctc
       61 tctggctcac cctcctcagt ctttgcacag gttctatggt ttcttctgag ctgactcagg
      121 accctgcagt ttctgtggcc ttgggacaga cagtcaggat tacctgccaa ggagacagcc
      181 tcagaagctc ttatgcaagc tggtaccaac agaggccagg ccaggcccct gtgctggtcg
      241 tctatggtaa caactaccgg ccctcaggga tcccagagcg attctctggc tcctactcac
      301 gaaacacagc ttccttgacc atctctgggg ctcaggtgga agatgaggct gactattact
      361 gtgactcctg ggacagcagc ggaacccaat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004298             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:21205:16892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004298
VERSION     KCWK01004298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21205:16892"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70036.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          155 c          128 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcgggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tgagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004299             386 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:24232:13542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004299
VERSION     KCWK01004299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24232:13542"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    18..348
                     /note="immunoglobulin light chain variable region"
     V_region        18..348
     V_segment       18..311
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <273..>320
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70037.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       312..348
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        349..>386
                     /gene="IGLC"
BASE COUNT           75 a          120 c          100 g           91 t
ORIGIN      
        1 acatggggtc ctgggcccag tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg
       61 ggcagagggt caccatctcc tgcactggga gcagctccaa cattggagat tattttgtgc
      121 agtggtacca gcaccttcca ggaacggccc ccaaactcct catttatgaa aataataagc
      181 gaccctcagg catttctgat cgattctctg gctcccagtc tggaacctca gcctccctga
      241 ccatcactgg actccagtct gaggatgagg ctgattatta ctgccagtcc tatgacagca
      301 gtttgattgc tgtgttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      361 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004300             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:14911:9620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004300
VERSION     KCWK01004300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14911:9620"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <342..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70038.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       382..414
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           92 a          140 c          129 g           91 t
ORIGIN      
        1 acatgggggg aggcagcatt gacggtgcct cagccatggc ctggaccctt ctcctcctcg
       61 gcctcctcgc ttactgcaca ggctctgcga cctcctatga attgactcag tcaccctcag
      121 tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac attggaacta
      181 aaactgtgca ctggtaccaa cagaagccac cgcagggccc tgtattggtc atctttgctg
      241 atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca gggaacaccg
      301 ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac tgtcaggtgt
      361 gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004301             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:8591:9158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004301
VERSION     KCWK01004301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:8591:9158"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..423
                     /note="immunoglobulin light chain variable region"
     V_region        93..423
     V_segment       93..386
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70039.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       387..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           87 a          150 c          114 g          110 t
ORIGIN      
        1 acatgggggc actcaggaca gtctccagca tggcctggtc tcctctcctc ctcacccttc
       61 tcattcactt cacagttcca gggtcctggg cccagtctgt gctgacgcag ccgccctcag
      121 tgtctggggc gcccgggcag agggtcacca tctcctgcac tgggagcagc tccaacattg
      181 gagattattt tgtgcagtgg taccagcacc ttccaggaac ggcccccaaa ctcctcatct
      241 atgaaaataa taagcgaccc tcagggattt ctgatcgatt ctctggctcc cagtctggaa
      301 cctcagcctc cctgaccatc actggactcc agtctgagga tgaggctgat tattactgcc
      361 agtcctatga cagcagtttg attgctgtgt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004302             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:16984:15469
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004302
VERSION     KCWK01004302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16984:15469"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..436
                     /note="immunoglobulin light chain variable region"
     V_region        93..436
     V_segment       93..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70040.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           88 a          161 c          112 g          113 t
ORIGIN      
        1 atggggactg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc ctgcctgtgc tgacccagcc aacctccctc
      121 tcagcatctc cgggagcatc ggccagactc agctgcacct tgagcagtgg caatgttggt
      181 agttacagca tattctggta ccagcagaag ccagggagtc ctccccggta ccttctttcc
      241 ttctactcag actcaagtaa ccaccaggac tctggagtcc ccagccgctt ctctggatcg
      301 aaagatgctt cagccaatgc agggctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccac atggcacagc agcgcttctt acatcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004303             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:21317:6220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004303
VERSION     KCWK01004303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21317:6220"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..451
                     /note="immunoglobulin light chain variable region"
     V_region        121..451
     V_segment       121..412
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70041.1"
                     /translation="DYYCQSYDSSLSGVLF"
     J_segment       417..451
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT           93 a          155 c          128 g          113 t
ORIGIN      
        1 acatgggggg aagctctgct tcagctgtgg gcacaggagg cagcactcag gacagtctcc
       61 agcatggcct ggtctcctct cctcctcacc cttctcattc actgcacagg gtcctgggcc
      121 cagtctgtgc tgacgcagcc gccctcagtg tctggggcgc ccgggcagag ggtcaccatc
      181 tcctgcagtg ggagcaactc caacattgga tactattatg tgcagtggta ccagcagctt
      241 ccaggaacgg cccccaaact cctcatctat gaaaataata aacgaccctc tggggtttct
      301 gatcgattct ctggctccca gtctggtacc tcagcctccc tgaccatcac tggactccag
      361 tctgaggatg aggctgatta ttactgccag tcctatgaca gcagtttgag tggtgtctta
      421 ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCWK01004304             520 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10604:9563
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004304
VERSION     KCWK01004304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 520)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 520)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..520
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10604:9563"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    137..482
                     /note="immunoglobulin light chain variable region"
     V_region        137..482
     V_segment       137..443
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <413..>454
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70042.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       445..482
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        483..>520
                     /gene="IGLC"
BASE COUNT           95 a          176 c          134 g          115 t
ORIGIN      
        1 acatggggga cactgcgata agagcggcct ggggcagccc aaccctgggt ctgtggcctc
       61 agaggtagcc gtgtccacca tggccctgac tcctctcctc ctcctgctcc tctctcactg
      121 cacaggttcc ctctcccagc ctgtgctgac tcagccaccc tccctgtctg catccccggg
      181 agcatcggcc agactcccct gcaccctgag cagtgacctc agtgttggta gtaaaaacat
      241 gtactggtac cagcagaagc cagggagcgc tcccaggtta ttcctgtact actactccga
      301 ctcagacaac cagctgggac ctggggtccc caatcgagtc tctggctcca aggagacctc
      361 aagtaacaca gcgtttttgc tcatctctgg gctccagcct gaggacgagg ccgattattt
      421 ctgccaggtg tttgacagta gtgttgtgtt cttcggagga gggacccgac tgaccgtcct
      481 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004305             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:24265:18247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004305
VERSION     KCWK01004305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24265:18247"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..278
                     /note="immunoglobulin light chain variable region"
     V_region        5..278
     V_segment       5..238
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <206..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70043.1"
                     /translation="DYYCAIGHMSGNYVF"
     J_segment       246..278
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>316
                     /gene="IGLC"
BASE COUNT           68 a           92 c           83 g           73 t
ORIGIN      
        1 acatgggggc atcaatgttg ctggctacca cacacactgg taccagcaga agccagggag
       61 tcctccccgg tatcttctga gatataaatc agactcagat aagggccagg gctctggagt
      121 ccccagccgc ttctctggat ccaaagatgc ttcagcgaac acagggattt tacgcatctc
      181 tgggctccag tctgaggatg aggctgacta ttactgtgcc attgggcaca tgagcggtaa
      241 ttatgtcttc ggttctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac
      301 ggtcactctg ttcccg
//
LOCUS       KCWK01004306             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:18584:10839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004306
VERSION     KCWK01004306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18584:10839"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70044.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          159 c          120 g          107 t
ORIGIN      
        1 acatggggga ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca actgcacctt gagcagtggc gtcaatgtgg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctgt
      241 actaccagtc agactcaagg aagcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggctgt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc ctatggcaca gcagcgcttc ttgcatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004307             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:14874:3201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004307
VERSION     KCWK01004307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14874:3201"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..357
                     /note="immunoglobulin light chain variable region"
     V_region        9..357
     V_segment       9..318
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <285..>329
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70045.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       320..357
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        358..>395
                     /gene="IGLC"
BASE COUNT           85 a          121 c           93 g           96 t
ORIGIN      
        1 acatggggca gcctgtgctg actcagccaa cctccctctc agcatctcct ggagcatcag
       61 ccagactcac ctgcaccttg aacagtggca tcagtgttgc taattacagg atattctggt
      121 accaccagaa gccagggagt cctccccggt atcttctgaa ctaccacaca gactcagata
      181 ttcatcaggg ctctggagtc cccagccgct tctctggatc caaagatgct tcggccaatg
      241 cagggatttt actcatctct ggactccagt ctgaggatga ggctgactat tactgtatga
      301 tttggcacaa caatgcttat tgggttttcg gcggagggac ccggctaacc gtcctaggtc
      361 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004308             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:15866:5664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004308
VERSION     KCWK01004308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15866:5664"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..403
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70046.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           87 a          163 c          119 g          111 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggta gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaaa cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattattt ctgccagctg tttgacagta gtgttgtgtt cttcggagga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004309             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:14098:2791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004309
VERSION     KCWK01004309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14098:2791"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70047.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           96 a          155 c          122 g          109 t
ORIGIN      
        1 acatggggaa gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata atgtgtcctg gtaccagcac ctcccaggaa
      241 cagctcccaa actcctcatc tattataatg atcaacgagg ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcgtggg atgatagcct gagcagttac atcttcgctg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actttgttcc
      481 cg
//
LOCUS       KCWK01004310             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:21484:11683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004310
VERSION     KCWK01004310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21484:11683"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..240
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <202..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70048.1"
                     /translation="DYYCQSADSSANHPLF"
     J_segment       243..277
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>315
                     /gene="IGLC"
BASE COUNT           79 a           84 c           85 g           67 t
ORIGIN      
        1 acatggggga tcacctgctc tggagaaata ctggcaaaaa aatatgctca gtggttccag
       61 cagaagccag gccaggcccc tgtgttggtg atatataaag acagtgagag gccctcaggg
      121 atccctgaac gattctctag ttccagttca gggacaacag ttaccttgac catcagtggg
      181 gcccaggtag aagatgaggc tgactattac tgtcaatcag cagacagcag tgctaatcat
      241 ccgttattcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      301 gtcactctct tcccg
//
LOCUS       KCWK01004311             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:23267:3661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004311
VERSION     KCWK01004311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23267:3661"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..271
                     /note="immunoglobulin light chain variable region"
     V_region        8..271
     V_segment       8..232
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <199..>243
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70049.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       234..271
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        272..>309
                     /gene="IGLC"
BASE COUNT           66 a           88 c           76 g           79 t
ORIGIN      
        1 acatggggtg ttgctaatta caggatattc tggtaccacc agaagccagg gagtcctccc
       61 cggtatcttc tgaactacca cacagactca gatattcatc agggctctgg agtccccagc
      121 cgcttctctg gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc
      181 cagtctgagg atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt
      241 ttcggcggag ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact
      301 ctcttcccg
//
LOCUS       KCWK01004312             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:17268:20346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004312
VERSION     KCWK01004312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17268:20346"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..391
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70050.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       393..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          155 c          119 g          102 t
ORIGIN      
        1 acatggggga caggaggcag cactcaggac agtctccagc atggcctcgt ctcctctcct
       61 cctcaccctt ttcattcact gcacagggtc ctgggcccag tctgtgctga cacagccgcc
      121 ctcagtgtct ggggccccag ggcagagggt caccatctcc tgcactggga gcagctccaa
      181 cattggaggt tattatatat cctggtacca gcagctccca ggaacggccc ccaaactcct
      241 cgtctatgac aataataagc gaccctcagg ggtttctgac cgattctctg gctccaagtc
      301 tggttcctca gccaccctga ccatcactgg gctccagact gaggatgagg ctgattatta
      361 ctgccagtcc tatgacagca gtctgagtgc tcgggtattc ggcggaggga cccggctaac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004313             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:13418:22857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004313
VERSION     KCWK01004313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:13418:22857"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70051.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>460
                     /gene="IGLC"
BASE COUNT           94 a          143 c          123 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaagatc acctgctctg gagatgcact
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgtttatcat
      241 cgatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004314             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:10086:19642
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004314
VERSION     KCWK01004314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10086:19642"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..436
                     /note="immunoglobulin light chain variable region"
     V_region        103..436
     V_segment       103..399
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70052.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       402..436
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           87 a          156 c          129 g          102 t
ORIGIN      
        1 acatgggggt gtggctcagg aagcagagcc tggagcgtct ccaccatggc ctgggctcca
       61 ctcctcctca ccctcctcgc tcactgcaca gggtcttggg ctgaggttct gttcacgcag
      121 ccccattctg tgtcggggtc tccggggcag acggtcacca tctcctgtac ccgcagcaga
      181 ggcaacattg acaatagtta tgtgcagtgg taccagcagc gcccgggcag tgccccgacc
      241 acagtgattt acagagatga ccaaagagcc tctggggtcc ctgatcggtt ctctggctcc
      301 atcgacagct cctccaactc tgcctccctc accatctctg ggctgaagtc tgaggacgag
      361 gctgactact actgtcagtc tactgatggc aactacaatc ggttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004315             400 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:15959:12112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004315
VERSION     KCWK01004315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 400)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 400)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15959:12112"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    32..362
                     /note="immunoglobulin light chain variable region"
     V_region        32..362
     V_segment       32..323
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <287..>334
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70053.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       325..362
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        363..>400
                     /gene="IGLC"
BASE COUNT           77 a          124 c          106 g           93 t
ORIGIN      
        1 acatgggatt cactgcacag ggtcctgggc ccagtctgtg ctgacgcagc cgccctcagt
       61 gtctggggcg cccgggcaga gggtcaccct ctcctgcact gggagcagct ccaacattgg
      121 agattattat gtgcagtggt accagcagct tccaggaacg gcccccaaac tcctcatcta
      181 tgaaaataat aagcgaccct caggggtttc tgatcgattc tctggctccc agtctggtac
      241 ctcagcctcc ctgaccatca ctggactcca gtctgacgat gaggctgatt attactgtca
      301 gtcctatgat agcagcctga gtgttgtgtt attcggagga gggacccggc tgaccgtcct
      361 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004316             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:8796:11697
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004316
VERSION     KCWK01004316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8796:11697"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70054.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          160 c          113 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagttacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaaa tgcttcaacg aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      421 ggactcgggt caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004317             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:22295:16177
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004317
VERSION     KCWK01004317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22295:16177"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    65..410
                     /note="immunoglobulin light chain variable region"
     V_region        65..410
     V_segment       65..373
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70055.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       374..410
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>448
                     /gene="IGLC"
BASE COUNT           87 a          152 c          107 g          102 t
ORIGIN      
        1 acatgggatg gccctgactc ctctcctcct cctgctcctc tctcactgca caggttccct
       61 ctcccagcct gtgctgactc agccaccctc cctgtctgca tccccgggag catcggccag
      121 actcccctgc accctgagca gtgacctcag tgttggtaat aaaaacatgt actggtacca
      181 acagaagcca gggagcgctc ccaggttatt cctgtactac tactccgact cagacaagca
      241 gctgggacct ggggtcccca atcgagtctc tggctccaag gagacctcaa ctaacacagc
      301 gtttttgctc atctctgggc tccagcctga ggacgaggcc gattattact gtcaggtgta
      361 tgacagtagt gctgtgttat tcggaggagg gacccgactg accgtcctag gtcagcccaa
      421 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004318             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:19296:8953
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004318
VERSION     KCWK01004318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19296:8953"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70056.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       216..251
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           57 a           82 c           89 g           61 t
ORIGIN      
        1 acatggggga ggtgaagttg tgaattggta ccagcagaag ccaccgcagg cccctgtgtt
       61 ggtcatctat gctgatggcg agcggccctc agggatccct gagcgattct ctggctccaa
      121 atcagggaac acggccaccc tgaccatcag cggggtcgag gccggagatg aggctgacta
      181 ttactgtcag gtgtgggacc ttaatagtca tcatctgtta ttcggaggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004319             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15412:4743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004319
VERSION     KCWK01004319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15412:4743"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70057.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          160 c          124 g          111 t
ORIGIN      
        1 acatggggtg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga ggccagggag cgctcccagg
      241 ttattcctgt attactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaggtaac acagcgtttt tgctcatctc tggactccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004320             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:11007:13612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004320
VERSION     KCWK01004320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:11007:13612"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..386
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70058.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       387..418
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>456
                     /gene="IGLC"
BASE COUNT           93 a          138 c          126 g           99 t
ORIGIN      
        1 acatgggggg gctcagaagc agagctctgg ggtgtctcca ccatggcctg gactcctctc
       61 tggctcaccc tcctcagtct ttgcacaggt tctgtggttt cttctgagct gactcaggac
      121 cctgcagtgt ctgtggcctt gggacagaca gtcaggatca cctgccaagg agacagcctc
      181 agaagttatt atgcaagttg gtaccagcag aagccaggcc aggcccctat actggtcgtc
      241 tatggtaaca attaccggcc ctcagggatc ccagagcgat tctctggctc cagtacacga
      301 aacacagctt ccttgaccat cactggggct caggtggaag atgaggctga ctattactgt
      361 gactcctggg acagccgcgg aacccaattc ggaggaggga cccggctgac cgtcctaggt
      421 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004321             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:8813:21610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004321
VERSION     KCWK01004321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8813:21610"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..252
                     /note="immunoglobulin light chain variable region"
     V_region        8..252
     V_segment       8..214
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <180..>224
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70059.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       218..252
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        253..>290
                     /gene="IGLC"
BASE COUNT           62 a           88 c           79 g           61 t
ORIGIN      
        1 acatggggta ctggtaccag cagaagccag gaagcgctcc caggttattg ctgtattacc
       61 actccgaccc agacaagcag ctgggacctg gggtccccaa tcgagtctct ggctccaagg
      121 agacctcaag taacacagcg tttttgctca tctctgggct ccagcctgag gacgaggccg
      181 attattactg tcaggtgtat gacagtagtg ccaacacgtt attcggagga gggacccggc
      241 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004322             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:23011:18283
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004322
VERSION     KCWK01004322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23011:18283"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70060.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           89 a          161 c          120 g          110 t
ORIGIN      
        1 atgggggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggta ataaaaacat gtactggtac caacagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aactaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcaggtg tttgacagta gtgctgtgtt attcggagga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004323             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:3095:12160
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004323
VERSION     KCWK01004323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:3095:12160"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..419
                     /note="immunoglobulin light chain variable region"
     V_region        89..419
     V_segment       89..382
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70061.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       383..419
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           88 a          152 c          113 g          104 t
ORIGIN      
        1 acatgggcgg cactctcggg acatctccac catggcctgg gatctgctcc tcttcaccct
       61 cctcactcag ggcacaggat cctgggctca ggctgccctg actcagcctc cctcaatgtc
      121 tgggtctcct ggacagtcgg tcaccatctc ctacactgga accagcagtg acattggtgg
      181 ttataaccgt gtctcctggt accaacagca cccaggcaaa gaccccaaat tcatgattta
      241 tgaggtcagt caacggccct caggggtctc tgatcgtatc tctggctcca agtctggcaa
      301 cacggcctcc ctgaccatct ctgggctcca gactgaggat gaggctggtt attactgcag
      361 ctcatttgca ggtaccaaca ctggcttaat cggtggaggg acccggctga ccgtcctagg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004324             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:14082:6937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004324
VERSION     KCWK01004324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14082:6937"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70062.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       402..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           94 a          156 c          120 g          107 t
ORIGIN      
        1 acatgggggg tggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc aagcctatgc tgactcagcc ggcctccctc
      121 tcagcatctc ctggagcatc agccagtctc acatgcacct tcggcggtgg catcaatgtt
      181 gctggctacc acatacactg gtaccaacag aagccaggga gtcccccccg gtatcttctg
      241 aggtacaaat cagactcaga taagggccag ggctctggag tcaccagccg cttctctgga
      301 tccaaagatg cttcagcgaa cacagggatt ttacgcatct ctgggctcca gtctgaggat
      361 gaggctgact attactgtgc cattgggcac agcagcggtg attacatctt cggtgctggg
      421 acccgactca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01004325             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12088:3368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004325
VERSION     KCWK01004325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12088:3368"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..263
                     /note="immunoglobulin light chain variable region"
     V_region        4..263
     V_segment       4..225
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70063.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       231..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           64 a           87 c           92 g           58 t
ORIGIN      
        1 acatggtgga gacaagattg gaagtgaagt tgtgaactgg taccagcaga agccagcgca
       61 cgcccctgtg ctggtcatct atgctaatag cgaacggccc tcagggatcc ctgagcgatt
      121 ctctggctcc aaatcaggga acacggccac cctgaccatc agcggggtcg aggccggggg
      181 tgaggctgac tattactgtc aggtgtggga catgcgtagt gatcaaccgc tattcggcgg
      241 agggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01004326             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18277:17886
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004326
VERSION     KCWK01004326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18277:17886"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70064.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          156 c          128 g          113 t
ORIGIN      
        1 acatgggggg ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggagat ttttatgtgc agtggtacca gcaccttcca
      241 ggaacggccc ccagactcct catctatgaa aataataagc gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tggaacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtttgattgc tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004327             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:4966:16974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004327
VERSION     KCWK01004327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4966:16974"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70065.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          158 c          121 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacggg cctcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004328             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:7539:10373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004328
VERSION     KCWK01004328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7539:10373"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..399
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70066.1"
                     /translation="DYYCQSYDSLSAILF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          157 c          129 g          108 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcccg ggcccagtct
      121 gtactgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac catttcctgc
      181 actgggagca gctccaacat cggggcgggt tattatgtgc agtggtacca gcagcttcca
      241 ggaacggccc ccaaactcct catctatgaa aatgataagc gaccctcagg ggtttctgat
      301 cgattctctg gctccaagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagcc tgagcgctat attattcggg
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004329             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:20622:16821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004329
VERSION     KCWK01004329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20622:16821"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70067.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       402..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           91 a          157 c          113 g          113 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagt cagactcagc tgcaccttga gcagtggcat caatgttggt
      181 tcttacacca tattctggta ccagcagaag ccagggagtc ctccccggtt ccttctgtac
      241 tactactcag actcaaataa tcaccagggg tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagccaatgc agggctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccat gtggcacagc agcgcttatg ccttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004330             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:13705:8447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004330
VERSION     KCWK01004330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13705:8447"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..418
                     /note="immunoglobulin light chain variable region"
     V_region        101..418
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70068.1"
                     /translation="DYYCYSSDSNSEWLF"
     J_segment       390..418
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>459
                     /gene="IGLC"
BASE COUNT           97 a          140 c          124 g           98 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatagcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgaga tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttcccgca gaaggcaggc cagcccccta tggtgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttactcatca gacagcaata gtgaatggct attcgacgga gggacccggc tgaccgtcgt
      421 aggtcagccc aaggctgccc cctcggtcac tctcttccg
//
LOCUS       KCWK01004331             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:7417:6619
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004331
VERSION     KCWK01004331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:7417:6619"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..248
                     /note="immunoglobulin light chain variable region"
     V_region        8..248
     V_segment       8..212
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>220
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70069.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       216..248
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        249..>286
                     /gene="IGLC"
BASE COUNT           62 a           83 c           83 g           58 t
ORIGIN      
        1 acatggggga actaaaactg tgcactggta ccagcagaag ccaccgcagg gccctgtatt
       61 ggtcatcttt gctgatagta aacggccctc agggatccct gagcgattct ctggctccaa
      121 ctcagggaac accgccaccc tgaccatcag cagggtcgag gccggggatg aggctgacta
      181 ttactgtcag gtttgggaca gtagtagtaa atggatattc ggcgggggga cccggctaac
      241 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004332             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:18208:20017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004332
VERSION     KCWK01004332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18208:20017"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..403
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70070.1"
                     /translation="DYHCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          163 c          113 g          106 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagtcagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacacacac tggtaccaac agaagccagg gagtcccccc cgatatcttc
      241 tgaaatacaa atcagacaca gaccagggcc aggggtctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggtc ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctatcactgt gccattggtc acagcagcgg tccatacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004333             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:5527:6022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004333
VERSION     KCWK01004333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5527:6022"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..240
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70071.1"
                     /translation="DYYCQVWDSTSDHYIF"
     J_segment       241..277
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>315
                     /gene="IGLC"
BASE COUNT           63 a           95 c           92 g           65 t
ORIGIN      
        1 acatgggggg tcacctgtgg gggagacaac attggaacta cgtttgtgca ctggtaccag
       61 cagaatccgc cgcaggcccc tgtgcaggtc ctctttgcgg ataacaaacg gccctcaggg
      121 atccctgaac gattctctgg ctccaactca gggaacaccg ccaccctgac catcagcggg
      181 gtcgaggccg gggatgaggc tgactattac tgtcaggtgt gggacagtac tagtgatcat
      241 tacatcttcg gtggtgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg
      301 gtcactctgt tcccg
//
LOCUS       KCWK01004334             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:10820:5144
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004334
VERSION     KCWK01004334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:10820:5144"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70072.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          146 c          129 g           98 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gtactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaataccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004335             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:9901:4984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004335
VERSION     KCWK01004335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9901:4984"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..287
                     /note="immunoglobulin light chain variable region"
     V_region        8..287
     V_segment       8..251
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70073.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       255..287
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>325
                     /gene="IGLC"
BASE COUNT           71 a           94 c           99 g           61 t
ORIGIN      
        1 acatggggga cagccggcca ggatcacctg tgggggagac aacattggaa ctaaaactgt
       61 gcactggtac cagcagaagc caccgcaggg ccctgtattg gtcatctttg ctgacagtaa
      121 acggccctca gggatccctg agcgattctc tggctccaac tcagggaaca ccgccaccct
      181 gaccatcagc ggggtcgagg ccggggatga ggctgactat tactgtcagg tgtgggacag
      241 tagtagtaaa tggatattcg gcggggggac ccggctaacc gtcctaggtc agcccaaggc
      301 tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004336             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:7813:4319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004336
VERSION     KCWK01004336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:7813:4319"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..260
                     /note="immunoglobulin light chain variable region"
     V_region        8..260
     V_segment       8..223
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <185..>232
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70074.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       225..260
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>298
                     /gene="IGLC"
BASE COUNT           62 a           94 c           73 g           69 t
ORIGIN      
        1 acatgggtcc aacattggag gttattatat atcctggtac cagcagctcc caggaacggc
       61 ccccaaactc ctcgtctatg acaataataa gcgaccctca ggggtttctg accgattctc
      121 tggctccaag tctggttcct cagccaccct gaccatcact gggctccaga ctgaggatga
      181 ggctgattat tactgccagt cctatgacag cagtctgagt gctcgggtat tcggcggagg
      241 gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004337             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:18869:12867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004337
VERSION     KCWK01004337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18869:12867"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..440
                     /note="immunoglobulin light chain variable region"
     V_region        94..440
     V_segment       94..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70075.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       406..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>480
                     /gene="IGLC"
BASE COUNT           92 a          161 c          112 g          115 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca cctttagcag tggcatcaat
      181 gttggtagtt acagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
      241 ctctactact actcagactc aagtaaacac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatgcaggc cttttactga tctctggggt ccagtctgaa
      361 gatgaggctg actattactg tgccatatgg cacagtagcg cttcttactt cttcggtact
      421 gggacccggc tcaccgtcct gggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004338             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17761:15888
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004338
VERSION     KCWK01004338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17761:15888"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..389
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70076.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       390..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           96 a          147 c          129 g           91 t
ORIGIN      
        1 acatgggggc tgggtctcag gaggcagcat tgacggtgcc tcagccatgg cctggaccct
       61 tctcctcctc ggcctcctcg cttactgcac aggctctgcg aactcctatg agctgactca
      121 gccaccctca gtgtcagcgg cctcaggaca gacggccagg atcacctgtg gcggagacaa
      181 cattggaatt aaaaatgtac actggtacca ccagaagcca ccgcaggccc ctgtgctggt
      241 catctttgct gataacaaac ggccctcagg gatccctgag cgattctctg cctccaactc
      301 agggaacacc gccaccctga ccatcagcag ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta gtagtaaatg ggtattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004339             284 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:23387:16848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004339
VERSION     KCWK01004339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 284)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:23387:16848"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..246
                     /note="immunoglobulin light chain variable region"
     V_region        7..246
     V_segment       7..209
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <174..>218
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70077.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       210..246
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        247..>284
                     /gene="IGLC"
BASE COUNT           56 a           89 c           79 g           60 t
ORIGIN      
        1 acatggggta ccagcagaag ccagggagtc ccccccggta tcttctgaga tacagatcag
       61 actcagataa gggccagggc tctggagtcc cccgccgctt ctctggatcc aaagatgctg
      121 cagcgaacac agggatttta cgcatctctg ggctccagtc tgaggatgag gctgactact
      181 actgtgccat tgggcacagc agcggtcctt acttcttcgg tggtgggacc cggctcaccg
      241 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004340             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:11266:13496
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004340
VERSION     KCWK01004340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11266:13496"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70078.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          162 c          121 g          109 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtaataaaaa catgtactgg taccaacaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaactaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004341             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:22761:5034
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004341
VERSION     KCWK01004341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22761:5034"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..237
                     /note="immunoglobulin light chain variable region"
     V_region        8..237
     V_segment       8..198
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <165..>209
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70079.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       200..237
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>275
                     /gene="IGLC"
BASE COUNT           57 a           82 c           69 g           67 t
ORIGIN      
        1 acatggggaa gccagggagt cctccccggt atcttctgaa ctaccacaca gactcagata
       61 ttcaccaggg ctctggagtc cccagccgct tctctggatc caaagatgct tcggccaatg
      121 cagggatttt actcatctct ggactccagt ctgaggatga ggctgactat tactgtatga
      181 tttggcacaa caatgcttat tgggttttcg gcggagggac ccggctaacc gtcctaggtc
      241 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004342             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:13327:2944
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004342
VERSION     KCWK01004342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13327:2944"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70080.1"
                     /translation="DYYCSAWDSSLTGGFF"
     J_segment       408..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           97 a          155 c          123 g          108 t
ORIGIN      
        1 acatggggtc agcttcagct gtggctagag aagacaggac tcaggacaat ctccagcatg
       61 gcctgcttcc ctctcatcct caccgtcctc actcactgtg caggatcctg ggcccagtct
      121 gtgctgactc aaccaccctc agcgtctggg gcccccgggc agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat tatgtatact ggtaccagca gttctcaggg
      241 aaggccccca aactcctcat ccataataat aatcagcgac cctcaggggt ccctgatcga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggaca tcagtgggct ccagtccgag
      361 gatgaggctg attattactg ctcagcatgg gatagcagtc tgaccggtgg ctttttcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004343             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:21258:12218
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004343
VERSION     KCWK01004343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21258:12218"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70081.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          162 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcttctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004344             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20310:13784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004344
VERSION     KCWK01004344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20310:13784"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70082.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          140 c          135 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tgctggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttgttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004345             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:6701:18048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004345
VERSION     KCWK01004345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6701:18048"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70083.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       410..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          157 c          129 g          106 t
ORIGIN      
        1 catgggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcctcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata gtgtatcctg gtaccagcag ctcccagaaa
      241 cggctcccaa actcctcatc ttttataatg atcggcgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagcggtccg gtattcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004346             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:19533:14533
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004346
VERSION     KCWK01004346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:19533:14533"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70084.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          157 c          122 g          110 t
ORIGIN      
        1 acatgggggc agcctcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgttgactc agcctccctc agcgtctgag gccgccggga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtatcct ggtaccaaca actcccagaa
      241 acggctccca aactcctcat gtattataat catcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacttcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagtgtgg gatgatagcc tgaccggtta catcttcggt
      421 actgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004347             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17491:14336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004347
VERSION     KCWK01004347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17491:14336"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70085.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaattcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagcactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004348             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:7723:7828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004348
VERSION     KCWK01004348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7723:7828"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..388
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70086.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       390..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          149 c          121 g          107 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag cagctccaac
      181 attggaggtt attatgtgca gtggtaccaa cagcttccag gaacggcccc caaactcctc
      241 atctatgaaa atgataaacg accctcaggg gtttctgatc gattctctgg ctcccagtct
      301 gattcctcag cctccctgac cgtcactgga ctccagtctg aggatgaggc tgattattac
      361 tgccagtcct atgacagcag cttgagtgtt gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004349             310 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:17600:6271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004349
VERSION     KCWK01004349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 310)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:17600:6271"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..272
                     /note="immunoglobulin light chain variable region"
     V_region        8..272
     V_segment       8..235
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <197..>244
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70087.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       236..272
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        273..>310
                     /gene="IGLC"
BASE COUNT           63 a           97 c           79 g           71 t
ORIGIN      
        1 acatggggga accagcagtg acatcggcgg ttataactat gtctcctggt accaacacca
       61 tccagacaca gcccccaaac tcatgattta tgaggtcact aagcggccct caggggtctc
      121 tgatcgcttc tctggctcca agtctggcaa cacggcctcc ctgaccatct ctgggctcca
      181 ggctgaggac gaggctgatt attactgctg ctcacatgca ggcagtgata ttttcgtgtt
      241 attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac
      301 tctcttcccg
//
LOCUS       KCWK01004350             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:11214:17183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004350
VERSION     KCWK01004350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:11214:17183"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70088.1"
                     /translation="DYYCQVWDSDSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           96 a          142 c          132 g           90 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg tactgcgacc tcctatgaac tgactcagcc
      121 accctcagtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa aatgtgcact ggtaccagca gaagccagcg cagggccctg tattggtcat
      241 gtttgctgat accagacggc cctcagggat ccctgaccga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtgata gtaaatggat attcggcgga gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004351             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:8463:19068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004351
VERSION     KCWK01004351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:8463:19068"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70089.1"
                     /translation="DYYCSAWDSSLSGLLF"
     J_segment       408..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          156 c          122 g          107 t
ORIGIN      
        1 acatggggag cttcagctgt ggctagagaa gacaggactc aggacaatct ccagcatggc
       61 ctgcttccct ctcatcctca ccgtcctcac tcactgtgca ggatcctggg cccagtctgt
      121 gctgactcaa ccaccctcag cgtctggggc ccccgggcag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtagtta tgtatactgg taccagcagc tctctggaaa
      241 ggcccccaaa ctcctcatct ataataataa tcagcgaccc tcaggggtcc ctgatcgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agtccgagga
      361 tgaggctgat tattactgct cagcatggga tagcagcctg agcggtctgt tattcggagg
      421 agggacccgc ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01004352             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:21534:5336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004352
VERSION     KCWK01004352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21534:5336"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70090.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       414..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          163 c          124 g          109 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccccccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctaa tgtcttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004353             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:19085:12812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004353
VERSION     KCWK01004353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19085:12812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..417
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70091.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       418..454
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           92 a          157 c          127 g          116 t
ORIGIN      
        1 acatgggggg ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact tcacagttcc agggtcctgg
      121 gcccagtctg tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc
      181 atctcctgca ctgggagcag ctccaacatt ggagattatt ttgtgcagtg gtaccagcac
      241 cttccaggaa cggcccccaa actcctcatc tatgaaaata ataagcgacc ctcagggatt
      301 tctgatcgat tctctggctc ccagtctgga acctcagcct ccctgaccat cactggactc
      361 cagtctgagg atgaggctga ttattactgc cagtcctatg acagcagttt gattgctgtg
      421 ttattcggag gagggacccg ggtgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCWK01004354             359 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:18883:20808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004354
VERSION     KCWK01004354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 359)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 359)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18883:20808"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..321
                     /note="immunoglobulin light chain variable region"
     V_region        8..321
     V_segment       8..283
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <246..>293
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70092.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       285..321
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        322..>359
                     /gene="IGLC"
BASE COUNT           74 a          117 c           86 g           82 t
ORIGIN      
        1 acatggggcc tccctcagcg tctgaggccg ccaggaagag tgtcaccatc tcctgttctg
       61 gaagcacctc caacatcgga agcaataatg tatcctggta ccagcagctc ccaggaacag
      121 ctcccaaact cctcttttat tataatgatc aacgagcctc aggtgtctct gaccgattct
      181 cttgctccaa gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg
      241 aggctgatta ttactgcgca tcatgggatg ataccctgag cggctacatc ttcggtgctg
      301 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004355             357 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:8863:10570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004355
VERSION     KCWK01004355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 357)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:8863:10570"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..319
                     /note="immunoglobulin light chain variable region"
     V_region        7..319
     V_segment       7..280
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <250..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70093.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       282..319
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>357
                     /gene="IGLC"
BASE COUNT           73 a          109 c           96 g           79 t
ORIGIN      
        1 acatgggcat ccccgggagc atcggccaga ctcccctgca ccctgagcag tgacctcagt
       61 gttggtagta aaaacatgta ctggtaccag cagaagccag ggagcgctcc caggttattc
      121 ctgtactact actccgactc agacaagcag ctgggacctg gggtccccaa tcgagtctct
      181 ggctccaagg agacctcaag taacacagcg tttttgctca tctctgggct ccagcctgag
      241 gacgaggccg attatttctg ccaggtgttt gacagtagtg ttgtgttctt cggaggaggg
      301 acccgactga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004356             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:9169:15525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004356
VERSION     KCWK01004356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9169:15525"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70094.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          155 c          126 g          112 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac catctcctgc
      181 actgggagca gctccaacat tggagattat tatgtgcagt ggtaccagca ccttccagga
      241 acggccccca gactcctcat ctatgaaaat aataagcgac cctcaggggt ttctgatcga
      301 ttctctggct cccagtctgg aacctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagcagtt tgattgctgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004357             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:10128:14886
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004357
VERSION     KCWK01004357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10128:14886"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..379
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70095.1"
                     /translation="DYHCQVWDLNSHHLLF"
     J_segment       381..416
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           86 a          138 c          132 g           98 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacttttc tcctcctcgg
       61 cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc caccctcgat
      121 ttcagtgtcc ccaggacaga cggccagggt cacctgtggg ggagacaaca ttgggagtga
      181 agttgtgaac tggtaccagc agaagccacc gcaggcccct gtgttggtca tctatgctga
      241 tagcgagcgg ccctcaggga tccctgaacg attctctggc tccaaatcag ggaacacggc
      301 caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactatcact gtcaggtgtg
      361 ggaccttaat agtcatcatt tgttattcgg aggagggacc cggctgaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004358             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:14011:18057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004358
VERSION     KCWK01004358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14011:18057"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70096.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          163 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcggctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004359             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:19927:19412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004359
VERSION     KCWK01004359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19927:19412"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70097.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          158 c          121 g          109 t
ORIGIN      
        1 acatgggggc agcctcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtactgactc agcctccctc agcgtctgag gccgccggga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtatcct ggtaccaaca actcccagaa
      241 acggctccca aactcctcat gtattataat catcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacttcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagtatgg gatgatagcc tgaccggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004360             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:24656:11625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004360
VERSION     KCWK01004360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:24656:11625"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..389
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70098.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          144 c          132 g           94 t
ORIGIN      
        1 acatgggggc tgggtctcag gaggcagcat tgacggtgcc tcagccatgg cctggaccct
       61 tctcctcctc ggcctcctcg cttactgcac aggctctgcg acctcctatg aactgactca
      121 gtcaccctca gtgtcagcgg cctcaggaca gccggccagg atcacctgtg ggggagacaa
      181 cattggaact aaaactgtgc actggtacca gcagaagcca ccgcagggcc ctgtattggt
      241 catctttgct gatagtaaac ggccctcagg gatccctgag cgattctctg gctccaactc
      301 agggaacacc gccaccctga ccatcagcag ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtt tgggacagta gtagtaaatg gatattcggc ggggggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004361             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:17257:7742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004361
VERSION     KCWK01004361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17257:7742"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..403
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70099.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       408..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          160 c          113 g          114 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagtcaga ctcagctgca ccttgagcag tggcatcaat
      181 gttggttctt acaccatatt ctggtaccag cagaagccag ggagtcctcc ccggttcctt
      241 ctgtactact actcagactc aaataatcac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc caatgcaggg cttttactga tctctggact ccagtctgaa
      361 gatgaggctg actattactg tgccatgtgg cacagcagcg cttatgcctt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004362             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:18813:4327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004362
VERSION     KCWK01004362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18813:4327"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..255
                     /note="immunoglobulin light chain variable region"
     V_region        8..255
     V_segment       8..218
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <180..>227
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70100.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       219..255
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        256..>293
                     /gene="IGLC"
BASE COUNT           61 a           90 c           80 g           62 t
ORIGIN      
        1 acatgggcat tggaagtaag agtgtgcact ggtaccaaca caagccaccg caggccccta
       61 tcctggtcat ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct
      121 ccaaatcagg gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg
      181 actattactg tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc
      241 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004363             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:14525:9866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004363
VERSION     KCWK01004363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14525:9866"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..281
                     /note="immunoglobulin light chain variable region"
     V_region        8..281
     V_segment       8..244
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <212..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70101.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       247..281
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        282..>322
                     /gene="IGLC"
BASE COUNT           69 a           96 c           87 g           70 t
ORIGIN      
        1 acatgggagc ggtggcatca atgttgctgg ctaccatata cactggtacc agcagaagcc
       61 agggagtcct ccccggtatc ttctgagata caaatcagac tcagatcagg gccagggctc
      121 tggagtcccc agccgcttct ctggatccaa agatgcttca gcgaacacag ggattttacg
      181 catctctggg ctccagtctg aggatgaggc tgactattac tgtgccattg ggcacagcag
      241 cggtgattac atattcggtg ccgggacccg gctcaccgtc ccaggtcagc ccaaggcttc
      301 ccccacggtc actctgttcc cg
//
LOCUS       KCWK01004364             504 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:23324:3857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004364
VERSION     KCWK01004364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 504)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23324:3857"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    136..466
                     /note="immunoglobulin light chain variable region"
     V_region        136..466
     V_segment       136..432
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <394..>438
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70102.1"
                     /translation="DYYCSSYEGTNSFIF"
     J_segment       433..466
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        467..>504
                     /gene="IGLC"
BASE COUNT           94 a          166 c          134 g          110 t
ORIGIN      
        1 acatggggga taacacaggg ctgggggcag gcccagtgct ggggtctcag gaggcagcgc
       61 tctcaggacg tctccaccat ggtctgggct ctgctcctcc tcaccctcct cactcagggc
      121 acaggaccct gggctcaggc tgccctgact cagcctccct ctgtgtctgg gtctcccgga
      181 cagtcggtca ccatctcctg cacgggaacc agcagtgaca tcggtggtta taactatgtc
      241 tcctggtacc agcagcaccc aggcaaagcc cccaaactca tgatttatga tgtcagtaag
      301 cggccctcag gggtctctga tcgcttctct ggctccaaat ctggcaacac ggcctccctg
      361 accatctctg ggctccaggc tgaggatgag gctgattatt actgcagctc atatgaaggc
      421 accaacagtt tcatcttcgg tgttgggacc cggctcaccg tactaggtca gcccaaggct
      481 tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004365             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:8359:8770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004365
VERSION     KCWK01004365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8359:8770"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70103.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          161 c          112 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004366             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:7617:13424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004366
VERSION     KCWK01004366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7617:13424"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..237
                     /note="immunoglobulin light chain variable region"
     V_region        7..237
     V_segment       7..200
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <156..>209
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70104.1"
                     /translation="DYYCAAGYGSGSDWQWVF"
     J_segment       201..237
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>275
                     /gene="IGLC"
BASE COUNT           55 a           87 c           84 g           49 t
ORIGIN      
        1 acatggggta ccaccagaag ccaggccagg cccctgtatt ggtcatctac aaagatacca
       61 accggccctc agggatccct gagcgattct ctggctccaa ctcagggaac acggccaccc
      121 tgaccatcag cagggtcgag gctggggatg aggccgacta ttactgtgct gcaggctatg
      181 gcagtgggag cgactggcag tgggtattcg gcggggggac ccggctaacc gtcctaggtc
      241 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004367             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:15291:11416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004367
VERSION     KCWK01004367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15291:11416"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..255
                     /note="immunoglobulin light chain variable region"
     V_region        8..255
     V_segment       8..218
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <183..>227
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70105.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       219..255
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        256..>293
                     /gene="IGLC"
BASE COUNT           62 a           88 c           78 g           65 t
ORIGIN      
        1 acatgggcat gtactggtac cagcagaagc cagggagcgc tcccaggtca ttcctgtact
       61 actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc tctggctcca
      121 aggagacctc aactaacaca gcgtttttgc tcatctctgg actccagcct gaggacgagg
      181 ccgattatta ctgtcaggtg tatgacagta gtgctaatgt gttattcgga ggagggaccc
      241 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004368             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:10320:19778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004368
VERSION     KCWK01004368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10320:19778"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..446
                     /note="immunoglobulin light chain variable region"
     V_region        98..446
     V_segment       98..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70106.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       412..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           90 a          164 c          123 g          107 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcactgacct
      181 cagtgttggt ggtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac taccactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg gtcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtatgacagt agtgctaaca cgttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01004369             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:15211:7995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004369
VERSION     KCWK01004369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15211:7995"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70107.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           86 a          163 c          123 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta tttctgccag ctgtttgaca gtagtgttgt gttcttcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004370             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:14315:15780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004370
VERSION     KCWK01004370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:14315:15780"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70108.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          149 c          127 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtaca ctggtaccag cacaagccac cgcaggcccc tgttctgctc
      241 atcttttatt ataccaaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttgttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004371             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:3765:14801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004371
VERSION     KCWK01004371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:3765:14801"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..436
                     /note="immunoglobulin light chain variable region"
     V_region        91..436
     V_segment       91..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70109.1"
                     /translation="DYYCAIGHSSGYIF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           91 a          157 c          120 g          106 t
ORIGIN      
        1 acatgggggg tggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ctccctctcc aagcctatgc tgactcagcc ggcctccctc
      121 tcagcatctc ctggagcatc agccagtctc acatgcacct tcagtggtgg catcaatgtt
      181 gctggctacc acacacactg gtaccagcag aagccaggga gtcctccccg gtatcttctg
      241 agatacaaat cagactcaga taagggccag ggctctggag tccccagccg cttctctgga
      301 tccagagatg cttcagcgaa cacagggatt ttacgcatct ctgggctcca gtctgaggat
      361 gaggctgact attactgtgc cattgggcac agcagcggtt acatcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004372             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:16362:7441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004372
VERSION     KCWK01004372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16362:7441"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..390
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70110.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       395..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT          106 a          137 c          122 g          102 t
ORIGIN      
        1 acatgggggg ctgtggttct aggaggaaga gctctgggtg tctcaccatg acctggacca
       61 ctgttctgct cccctttctc actctctgca caggctctga ggcctcctat gagctgacac
      121 agccaccctc agtgtctgtg tccccaggac agacggccag gatcacctgc tctggagaaa
      181 tactggcaaa aaaatatact cagtggttcc aacagcagcc aggccaggcc cctttcctgg
      241 tgatatataa agacagtgag aggccctcag ggatccctga gcgattctct agctccagtt
      301 cagggacaac aattaccttg accatcagtg gggcccaggc agaagatgag gctgactatt
      361 actgtcaatc agtagacagc agtggaaatc ttccgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004373             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:8164:18287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004373
VERSION     KCWK01004373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:8164:18287"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70111.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagcgggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004374             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:4853:14701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004374
VERSION     KCWK01004374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:4853:14701"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    75..393
                     /note="immunoglobulin light chain variable region"
     V_region        75..393
     V_segment       75..361
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <324..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70112.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       362..393
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>431
                     /gene="IGLC"
BASE COUNT           88 a          133 c          115 g           95 t
ORIGIN      
        1 acaggggtgt ctccaccatg gcctggactc ctctctggct caccctcctc agtctttgca
       61 caggttctgt ggtttcttct gagctgactc aggaccctgc agtgtctgtg gccttgggac
      121 agacagtcag gatcacctgc caaggagaca gcctcagaag ttattatgca agttggtacc
      181 agcagaagcc aggccaggcc cctatactgg tcgtctatgg taacaattac cggccctcag
      241 ggatcccaga gcgattctct ggctccagta cacgaaacac agcttccttg accatcactg
      301 gggctcaggt ggaagatgag gctgactatt actgtgactc ctgggacagc cgcggaaccc
      361 aattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      421 ctctcttccc g
//
LOCUS       KCWK01004375             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:16335:17231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004375
VERSION     KCWK01004375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:16335:17231"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..389
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70113.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           89 a          152 c          120 g          110 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 actccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgatattg ggtattatca tgctgtgtct tggtaccagc atcatccagg caaagccccc
      241 aaactcatga tttatgaggt caataaacgg cccgcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 gattattact gtagctcata tgcaggcagc aacagtttat tcttcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004376             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:24609:20206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004376
VERSION     KCWK01004376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24609:20206"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70114.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          152 c          122 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgagc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004377             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:17456:5794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004377
VERSION     KCWK01004377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:17456:5794"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70115.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           88 a          164 c          120 g          114 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtggtaaaaa catttactgg taccagcaga agccagggcg cgctcccagg
      241 tttttcctgt actacaactc cgactcagac aagcagctgg gacctggggt ccccaatcgc
      301 gtctctggct ccaaggagac ttcaagtaac acagcgtttt tgctcatctc tggcctccag
      361 cctgaggacg aggccgatta ttactgtcac gtttatgaca gtagtactaa tgtgttattc
      421 ggaggaggga cccgtctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004378             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:21801:5508
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004378
VERSION     KCWK01004378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21801:5508"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70116.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          156 c          126 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgaa cctcgggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004379             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:8785:5075
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004379
VERSION     KCWK01004379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:8785:5075"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70117.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       414..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           92 a          157 c          123 g          116 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcacttcac agttccaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag attattttgt gcagtggtac cagcaccttc
      241 caggaacggc ccccaaactc ctcatttatg aaaataataa gcgaccctca ggcatttctg
      301 atcgattctc tggctcccag tctggaacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagtttgatt gctgtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01004380             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:8678:3229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004380
VERSION     KCWK01004380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8678:3229"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..436
                     /note="immunoglobulin light chain variable region"
     V_region        112..436
     V_segment       112..399
                     /gene="IGLV3-35"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70118.1"
                     /translation="DYYCGSWDNSGEHYIF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           94 a          147 c          125 g          108 t
ORIGIN      
        1 acatggggct ccccagctgt gggctcagaa gcagaactct gggtcgtctc caccatggcc
       61 tggacccctc ccctgctcat cctcctcact ctctgcacag gttccgtggt ttcctctggg
      121 ctgactcagg agcctgcatt gtctgtggcc ttgggacata cagtcaggat gacctgccaa
      181 ggagacagcc tcaaaaccta ttacacaagc tggtaccaac agaagccagg ccaggtccct
      241 gtgctggtca tctatggtaa caccaatagg ccctcaggga tcccaggccg attctctggc
      301 tcctggtcag gaaactcagg ttccttgacc atcactgggg ctcaggtgga agatgaggct
      361 gactattact gtggctcctg ggataacagt ggtgagcatt acatcttcgg tgatgggacc
      421 cggttcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004381             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:15349:17537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004381
VERSION     KCWK01004381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:15349:17537"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..436
                     /note="immunoglobulin light chain variable region"
     V_region        91..436
     V_segment       91..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70119.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           92 a          158 c          115 g          109 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgacccagcc aacctccctc
      121 tcagcatctc cgggagcatc agccagactc agctgcacct tgagcagtgg caatgttggt
      181 agttacagca tattctggta ccagcagaag ccagggagtc ctccccggta ccttctttac
      241 tactactcag actcaagtaa tcaccaggac tctggagtcc ccagccgctt ctctggatcg
      301 aaagatgctt cagccaatgc agggctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccac atggcacagc agcgcttctt acatcttcgg gggggggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004382             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:13420:8046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004382
VERSION     KCWK01004382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13420:8046"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70120.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          153 c          116 g          113 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcactgttg
      181 ctggctacca tatatattgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg tctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatatc tggactccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacaca gcagcggtga ttatatcttc ggtgctggga
      421 cccgtctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004383             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:8535:7955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004383
VERSION     KCWK01004383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8535:7955"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70121.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          156 c          117 g          115 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaagctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc ttctcctgca ctggaaccgg
      181 cagtgatttt gggtcttata atgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 ccaactcata atttttgagg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgctgctcat atgtaggcag caacacttac atcttcgatg ttgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01004384             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:12220:8806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004384
VERSION     KCWK01004384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12220:8806"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70122.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           92 a          155 c          126 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaac agtgtcgcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatgatga tcaacgagcc tcgggtgtct ctgaccgatt
      301 ctctggctcc aggtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agaggttaca tcttcggtga
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01004385             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:21953:13133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004385
VERSION     KCWK01004385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21953:13133"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70123.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       390..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           86 a          140 c          135 g          101 t
ORIGIN      
        1 acatggggga ctttgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctttacaggc tctgtggcct cctatgagtt gcctcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtaata gtgtccattg gtaccagcag aagccaccgc gggcccctgt attggtcatc
      241 tctgttgata gcgaacggcc ctcagggatc cctgagcgat tctctggttc cagatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg ataatattta taaatacgcg gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004386             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:25309:17558
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004386
VERSION     KCWK01004386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25309:17558"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70124.1"
                     /translation="AYYCQVWDSDTDHYIF"
     J_segment       215..251
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           61 a           89 c           79 g           60 t
ORIGIN      
        1 acatggggga actagttttg tgcactggta ccagcagaag ccagcgcagg cccctataca
       61 ggtcatctat gctgatacca aacggccctc agggatccct gagagattct ctggctccaa
      121 ctcagggaac accgccaccc tgaccatcag cggagtcgag gccggggatg aggctgccta
      181 ttactgtcag gtgtgggaca gtgatactga tcattacatc ttcggtgctg ggacccggct
      241 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004387             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:16811:13890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004387
VERSION     KCWK01004387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16811:13890"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70125.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       401..435
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           89 a          156 c          121 g          107 t
ORIGIN      
        1 acatgggggg ggatctcacg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtggccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc cggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt gttcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004388             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:8645:8685
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004388
VERSION     KCWK01004388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8645:8685"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..411
                     /note="immunoglobulin light chain variable region"
     V_region        81..411
     V_segment       81..372
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70126.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       374..411
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           83 a          144 c          116 g          106 t
ORIGIN      
        1 acatggggag gacagtctcc agcatggcct ggtctcctct cctcctcacc cttctcattc
       61 actgcacagg gtcctgggcc cagtctgtgc tgacgcagcc gccctcagtg tctggggcgc
      121 ccgggcagag ggtcaccatc tcctgcactg ggagcagctc caacattgga ggttattatg
      181 tgcagtggta ccagcagctt ccaggaacgg cccccaaact cctcatctat gaaaatgata
      241 aacgaccctc aggggtttct gatcgattct ctggctccca gtctgattcc tcagcctccc
      301 tgaccatcac tggactccag tctgaggatg aggctgatta ttactgccag tcctatgaca
      361 gcagcttgag tgttgtgtta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004389             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:20702:13185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004389
VERSION     KCWK01004389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20702:13185"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70127.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           91 a          152 c          126 g          111 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg agattattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccaaac tcctcatcta tgaaaatgat aaaagaccct caggggtttc tgatcgattc
      301 tctggctccc agtctgattc ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagcttga gtgttgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004390             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:7400:16398
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004390
VERSION     KCWK01004390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7400:16398"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70128.1"
                     /translation="DYYCQSGDSSGNHWVF"
     J_segment       389..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          107 a          132 c          127 g           97 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctgtg gagaaatact
      181 ggcaaaaaaa tatactcagt ggttccagca gaaggcaggc caggcccctc tgctggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagaga ttctctagct ccagtccagg
      301 gccaacattt accttgacca acagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagga gacagcagtg gtaatcattg ggtattcggc ggagggaccc ggctaagcgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004391             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:6907:17370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004391
VERSION     KCWK01004391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:6907:17370"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..262
                     /note="immunoglobulin light chain variable region"
     V_region        4..262
     V_segment       4..225
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <187..>234
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70129.1"
                     /translation="DYYCQVWDSSSDHVFF"
     J_segment       226..262
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        263..>300
                     /gene="IGLC"
BASE COUNT           65 a           85 c           90 g           60 t
ORIGIN      
        1 atggggggag acaacattag aagtaaaaat gtgaattggt accagcagaa gccaccgcag
       61 gcccccgcgc tggtcatcta ttatgatagc gaccggccct cagggatccc tgagcgattc
      121 tctggctcca actcagggaa caccgccacc ctgaccatca gcggggtcga ggccggggat
      181 gaggctgact attactgtca ggtgtgggac agtagtagtg atcatgtgtt tttcggagga
      241 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004392             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:8510:17957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004392
VERSION     KCWK01004392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8510:17957"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70130.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tttctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004393             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:13310:18071
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004393
VERSION     KCWK01004393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13310:18071"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70131.1"
                     /translation="DYYCCSHGGSNIFVLF"
     J_segment       403..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           84 a          158 c          125 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggcggttata actatgtctc ctggtaccaa cagcatccag acacagcccc
      241 caaactcatg atttttgagg tcactaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccgggctg aggacgaggc
      361 tgattattac tgctgctcac atggaggcag taatattttc gtcttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004394             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:16931:14494
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004394
VERSION     KCWK01004394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16931:14494"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70132.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           91 a          160 c          112 g          110 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccagggct ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt gctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004395             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:12256:10249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004395
VERSION     KCWK01004395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12256:10249"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..384
                     /note="immunoglobulin light chain variable region"
     V_region        63..384
     V_segment       63..348
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <312..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70133.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       349..384
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>422
                     /gene="IGLC"
BASE COUNT           89 a          136 c          114 g           83 t
ORIGIN      
        1 acatgggggc ctggaccctt ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga
       61 actcctatga gctgactcag ccaccctcag tgtcagcggc ctcaggacag acggccagga
      121 tcacctgtgg cggagacaac attggaatta aaaatgtaca ctggtaccac cagaagccac
      181 cgcaggcccc tgtgctggtc atctttgctg ataacaaacg gccctcaggg atccctgagc
      241 gattctctgc ctccaactca gggaacaccg ccaccctgac catcagcagg gtcgaggccg
      301 gggatgaggc tgactattac tgtcaggtgt gggacagtag tagtaaatgg gtattcggcg
      361 gagggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      421 cg
//
LOCUS       KCWK01004396             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:10883:4002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004396
VERSION     KCWK01004396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:10883:4002"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70134.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          162 c          123 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcttcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagcgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggttc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004397             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:14141:2632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004397
VERSION     KCWK01004397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14141:2632"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70135.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       398..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           84 a          156 c          118 g          115 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaagct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac cttctcctgc actggaaccg
      181 gcagtgattt tgggtcttat aatgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 cccaactcat aatttttgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgctgctca tatgtaggca gcaacactta catcttcgat gttgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004398             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:22043:21060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004398
VERSION     KCWK01004398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:22043:21060"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70136.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          163 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagccc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004399             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15946:15246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004399
VERSION     KCWK01004399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15946:15246"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..451
                     /note="immunoglobulin light chain variable region"
     V_region        121..451
     V_segment       121..412
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70137.1"
                     /translation="DYYCQSYDSSLSGVLF"
     J_segment       417..451
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT           94 a          155 c          127 g          113 t
ORIGIN      
        1 acatgggggg aagctctgct tcagctgtgg gcacaggagg cagcactcag gacagtctcc
       61 agcatggcct ggtctcctct cctcctcacc cttctcattc actgcacagg gtcctgggcc
      121 cagtctgtgc tgacgcagcc gccctcagtg tctggggcgc ccggacagag ggtcaccatc
      181 tcctgcagtg ggagcaactc caacattgga tactattatg tgcagtggta ccagcagctt
      241 ccaggaacgg cccccaaact cctcatctat gaaaataata aacgaccctc tggggtttct
      301 gatcgattct ctggctccca gtctggtacc tcagcctccc tgaccatcac tggactccag
      361 tctgaggatg aggctgatta ttactgccag tcctatgaca gcagtttgag tggtgtctta
      421 ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCWK01004400             364 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:20778:18228
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004400
VERSION     KCWK01004400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 364)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20778:18228"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..326
                     /note="immunoglobulin light chain variable region"
     V_region        8..326
     V_segment       8..288
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <251..>298
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70138.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       290..326
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        327..>364
                     /gene="IGLC"
BASE COUNT           79 a          112 c          102 g           71 t
ORIGIN      
        1 acatggggat ctgactcagc caccctcggt gtcagtgtcc ccaggacaga cggccaggat
       61 cacctgtggg ggagacaaca ttggaagtca aagtgtgcac tggtaccagc acaagccacc
      121 gcaggcccct gtactggtca tcttttatta taccgaacgg ccctcaggaa tccctgagcg
      181 attctctggc tccaaatcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      241 ggatgaggct gactattact gtcaggtgtg ggacacaact attgatcacg gcttattcgg
      301 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      361 cccg
//
LOCUS       KCWK01004401             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:9396:15106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004401
VERSION     KCWK01004401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:9396:15106"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..441
                     /note="immunoglobulin light chain variable region"
     V_region        111..441
     V_segment       111..402
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70139.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       404..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          153 c          125 g          110 t
ORIGIN      
        1 acatggggct tcagctgtgg gcacaggagg cagcactcag gacagtctcc agcatggcct
       61 ggtctcctct cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc
      121 tgacgcagcc gccctcagtg tctggggcgc ccgggcagag ggtcaccatc tcctgcactg
      181 ggagcagctc caacattgga ggttattatg tgcagtggta ccagcagctt ccaggaacgg
      241 cccccaaact cctcatctat gaaaatgata aacgaccctc aggggtttct gatcgattct
      301 ctggctccca gtctgatacc tcagcctccc tgaccatcac tggactccag tctgaggatg
      361 aggctgatta ttactgccag tcctatgaca gcagcttaag tgttgtgtta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004402             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:21806:15564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004402
VERSION     KCWK01004402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21806:15564"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70140.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          163 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcataggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004403             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:23954:11433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004403
VERSION     KCWK01004403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:23954:11433"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..406
                     /note="immunoglobulin light chain variable region"
     V_region        82..406
     V_segment       82..363
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <331..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70141.1"
                     /translation="DYYCQVWDGSSHHRIF"
     J_segment       374..406
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           91 a          139 c          127 g           87 t
ORIGIN      
        1 acatggggac agatctcctc cagcagcagc cgctgactct gctgatttgc atcatgggcc
       61 actctctcca gctgtgcgac ctcctatgag ctgactcagc caccctcggt gtcagcggcc
      121 tcaggacaga cggccaggat cacctgtggg ggaaacaaca ttggaagtaa atatgtgtcc
      181 tggtgccagc agaagccagc gcaggcccct gtacaggtca tctatgctga taccaaacgg
      241 ccctcaggga tccctgagcg attctctggc tccaactcag ggaacaccgc caccctgacc
      301 atcagcgggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg ggacggtagt
      361 agtcatcatc ggatattcgg cggagggacc cggctgaccg tcctaggtca gcccaaggct
      421 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004404             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:18798:8723
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004404
VERSION     KCWK01004404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18798:8723"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70142.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           87 a          157 c          126 g          110 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggtacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcagc ctccctcagc gtctgaggcc gccgggaaga gtgtctccat ctcctgttct
      181 ggaagcagct ccaacatcgg aagtcatagt gtctcctggt accagcagct cccaggaaca
      241 gctcccaaac tcctcatcta ttatagtgat caacgagcct caggtgtctc tgaccgattc
      301 tctggctctc agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat
      361 gaggctgatt attactgcgc agcatgggat gatagcctga gcggttacat cttcggtgct
      421 gggacccggc tcgccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004405             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12928:9044
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004405
VERSION     KCWK01004405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12928:9044"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    157..312
                     /note="immunoglobulin light chain variable region"
     V_region        157..312
     V_segment       157..275
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70143.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       276..312
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>350
                     /gene="IGLC"
BASE COUNT           56 a          124 c           87 g           83 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc caatcgagtc tctggctcca
      181 aggagacctc aactaacaca gcgtttttgc tcatctctgg gctccagcct gaggacgagg
      241 ccgattatta ctgtcaggtg tttgacagta gtgctgtgtt attcggagga gggacccgac
      301 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004406             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:23816:7229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004406
VERSION     KCWK01004406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23816:7229"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..266
                     /note="immunoglobulin light chain variable region"
     V_region        8..266
     V_segment       8..229
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70144.1"
                     /translation="DYTCQVWDSESDYYIF"
     J_segment       230..266
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           67 a           85 c           90 g           62 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaattaa atttgtccac tggtaccagc agaagccagc
       61 gcaggcccct gtgaaggtca tctatggtga tgacaaacgg ccctcaggga tccctgagag
      121 attctctggc tccaattcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      181 ggatgaggct gactatacct gtcaggtgtg ggacagtgag agtgattatt acatcttcgg
      241 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      301 cccg
//
LOCUS       KCWK01004407             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:23332:20017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004407
VERSION     KCWK01004407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:23332:20017"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..260
                     /note="immunoglobulin light chain variable region"
     V_region        5..260
     V_segment       5..222
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <185..>232
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70145.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       224..260
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>298
                     /gene="IGLC"
BASE COUNT           65 a           92 c           80 g           61 t
ORIGIN      
        1 acatggggac aacattggaa gtcaaagtgt acactggtac cagcacaagc caccgcaggc
       61 ccctgttctg ctcatctttt attataccga acggccctca ggaatccctg agcgattctc
      121 tggctccaaa tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga
      181 ggctgactat tactgtcagg tgtgggacac aactattgat cacggcttgt tcggaggagg
      241 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004408             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:8396:5940
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004408
VERSION     KCWK01004408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8396:5940"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70146.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       400..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          157 c          124 g          105 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggttat aactatgtct cctggtacca acagcatcca ggcacagccc
      241 ccaaagtcat gatttatgag gtcagtaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tatacaggca tcaacagtta catcttcggt ggtgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004409             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:14740:3296
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004409
VERSION     KCWK01004409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14740:3296"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70147.1"
                     /translation="DYYCQVYDSRANTLF"
     J_segment       414..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>486
                     /gene="IGLC"
BASE COUNT           92 a          165 c          124 g          105 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcactgac
      181 ctcagtgttg gtggtaaaaa catgtactgg taccagcaga agccaggaag cgctcccagg
      241 ttattgctgt attaccactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctgcag
      361 cctgaggacg aggccgatta ttactgtcag gtctatgaca gtagagccaa cacgttattc
      421 ggaggaggga cccggctgac cgtcccaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004410             390 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:18085:18705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004410
VERSION     KCWK01004410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 390)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 390)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..390
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18085:18705"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    22..352
                     /note="immunoglobulin light chain variable region"
     V_region        22..352
     V_segment       22..315
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <277..>324
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70148.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       316..352
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        353..>390
                     /gene="IGLC"
BASE COUNT           78 a          125 c          100 g           87 t
ORIGIN      
        1 acatgggcag ggtcctgggc ccagtctgtg ctgactcagc ctccctcagc gtctgaggcc
       61 gccaggaaga gtgtcaccat ctcctgttct ggaagcagct ccaacatcgg aagtaataat
      121 gtgtcctggt accagcacct cccaggaaca gctcccaaac tcctcatcta ttataatgat
      181 caacgaggct caggtgtctc tgaccgattc tctggctcca agtctggcac gtcagcctcc
      241 ctggccatca gtgggctcca gaccgaggat gaggctgatt attactgcgc agcgtgggat
      301 gatagcctga gcagttacat cttcgctgct gggacccggc tcaccgtcct aggtcagccc
      361 aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004411             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:20294:15027
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004411
VERSION     KCWK01004411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20294:15027"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70149.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          161 c          122 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gcaataaaaa catatactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtcat acagcgtttt tgctcatttc tggactccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgacg atagtgctgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004412             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:18670:15361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004412
VERSION     KCWK01004412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18670:15361"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70150.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          163 c          108 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccaac agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004413             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18182:4188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004413
VERSION     KCWK01004413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18182:4188"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70151.1"
                     /translation="DYFCCSYAGSDTFVLF"
     J_segment       404..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           84 a          162 c          124 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caacaacatc cagccacagc
      241 ccccaaactc gtgatttatg aggtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct ggcctccagc ctgaggacga
      361 ggctgattat ttctgctgct catatgcagg cagcgacact ttcgtgttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004414             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15726:11342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004414
VERSION     KCWK01004414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15726:11342"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70152.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       391..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          138 c          138 g           99 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagg
      121 caccctcgat ttcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtgaac tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tgtatgctga tagcgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacatgaat agtcatcatc tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004415             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12576:14544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004415
VERSION     KCWK01004415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12576:14544"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..398
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70153.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           90 a          154 c          118 g          109 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 actccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcag tggaaccagc
      181 agtgatattg ggtattatca tgctgtgtct tggtaccaac atcgtccagg caaagccccc
      241 aaactcatga tttatgaggt caataaacgg cccgcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaagct
      361 gattattact gcagctcata tgcaggcagc aacactttat tcttcggacg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004416             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:22016:14960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004416
VERSION     KCWK01004416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22016:14960"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70154.1"
                     /translation="DYYCHVYDSSSNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          163 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcattttt gctcatctcc gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtagtaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004417             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:16674:20463
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004417
VERSION     KCWK01004417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16674:20463"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70155.1"
                     /translation="DYYCLAWDTSLNWLF"
     J_segment       416..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           93 a          158 c          124 g          109 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctctccttc tcactctgct ggttcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagcatctgg ggcccccgga cagagggtca ccatctcctg
      181 cattagcagc agctccaaca tcggggcggc ttattatgtg tcctggtacc aacagtaccc
      241 aggaacagcc cccaaactcc tcatctttga aaacaataag cgaccttcag gggtttctga
      301 ccgattctct ggctccaagt ctggtccctc agcctccctg accatcactg gactccaatc
      361 tgaggatgag gctgattatt actgtttagc atgggatacc agcctgaatt ggctcttcgg
      421 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01004418             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:18784:5660
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004418
VERSION     KCWK01004418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:18784:5660"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70156.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          148 c          130 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt ccaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004419             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:5638:13702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004419
VERSION     KCWK01004419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5638:13702"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70157.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          107 a          136 c          122 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004420             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:4396:7426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004420
VERSION     KCWK01004420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:4396:7426"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..226
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70158.1"
                     /translation="DYYCQVWGMTRDHPVF"
     J_segment       229..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           62 a           87 c           95 g           57 t
ORIGIN      
        1 acatgggggg ggagaccaca ttggaattga ggttgtgaac tggtaccaac agaagccacc
       61 gcaggcccct gtggtggtct atcctaatag cgaacggccc tcagggatcc ctgagcgatt
      121 ctctggctcc aaatcaggga acacggccac cctgaccatc agcggggtcg aggccgggga
      181 tgaggctgac tattactgtc aggtgtgggg catgactagg gatcatccgg tattcggcgg
      241 agggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01004421             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:4880:4543
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004421
VERSION     KCWK01004421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:4880:4543"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..446
                     /note="immunoglobulin light chain variable region"
     V_region        95..446
     V_segment       95..409
                     /gene="IGLV5-107"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70159.1"
                     /translation="DYYCCTWHGSSKTQIF"
     J_segment       414..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          160 c          119 g          116 t
ORIGIN      
        1 acatggggac tggtagggct caggggctct gtccaccatg gcctggactc ttctccttct
       61 catgctcctc tctcactgca caggttccct ctcccagcct gtgctgactc agccatcttc
      121 ccattccgca tctcctggag cgccagccag actcacctgc acgctgagca gtggcttcag
      181 tgttggtgac ttctggatac ggtggtacca acaaaagcca gggagccctc cccggtatct
      241 cctgtactac cactcagact cagataacca ccgaggctct ggagttccca gccgcttctc
      301 tggatccaat gatgcatcag ccaatgcagg gattctcttt atctctgggc tccagcctga
      361 ggatgaggct gactattact gttgtacatg gcatggcagc tctaagactc agatattcgg
      421 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01004422             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:10164:17152
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004422
VERSION     KCWK01004422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10164:17152"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..431
                     /note="immunoglobulin light chain variable region"
     V_region        98..431
     V_segment       98..394
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70160.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       401..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           83 a          161 c          127 g           98 t
ORIGIN      
        1 acatggggga gagccctgag gagtctgcac catggcctgg accccaatcc tcctcctcct
       61 cctcactctc ctccttcact gcacagggtc tctctcccag cctgtggtga ctcagtcgtc
      121 ctctgcctct gcctccctgg gagcctcggt caagctcacc tgcactctga gcggtgggca
      181 cagcgactac accatcgcat ggcatcagca gcagcaaggg aaggcccctc ggtatttgat
      241 gtggcttaaa agtgatggca gccacagcaa gggggacggg atccctgatc gcttctccgg
      301 ctccagctcc ggggctgagc gctacctcac catctccaac ctccagtctg aggatgaggc
      361 tgattattac tgtcagacct gggagactgg cattcaggtg ttcggcggag ggacccggct
      421 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004423             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:10081:7463
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004423
VERSION     KCWK01004423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10081:7463"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..456
                     /note="immunoglobulin light chain variable region"
     V_region        111..456
     V_segment       111..419
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <387..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70161.1"
                     /translation="DYYCQVFDDSAVLF"
     J_segment       423..456
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           93 a          167 c          122 g          112 t
ORIGIN      
        1 acatggggga gcccaaccct gggtctgtgg cctcagaggt agccgtgtcc accatggccc
       61 tgactcctct cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc
      121 tgactcagcc accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc
      181 tgagcagtga cctcagtgtt ggaaataaaa acatatactg gtaccagcag aagccaggga
      241 gcgctcccag gttattcctg tactactact ccgactcaga caaccagctg ggacctgggg
      301 tccccaatcg agtctctggc tccaaggaga cctcaagtca tacagcgttt ttgctcattt
      361 ctgggctcca gcctgaggac gaggccgatt attactgtca ggtgtttgac gatagtgctg
      421 tattattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      481 tcactctctt cccg
//
LOCUS       KCWK01004424             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:12298:6401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004424
VERSION     KCWK01004424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12298:6401"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70162.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       399..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          157 c          123 g          105 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa cagcatccag gcacagcccc
      241 caaagtcatg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat atacaggcat caacagttac atcttcggtg gtgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01004425             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:12002:6304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004425
VERSION     KCWK01004425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12002:6304"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..402
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70163.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           83 a          157 c          128 g          108 t
ORIGIN      
        1 acatgggggg ctggggtctc aggaggcagc gctctcggga cgtctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag tctgccctga
      121 ctcagcctcc ctcagtgtcc aagtctcttg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga cattggtggt tatgatggcg tctcctggta ccagcaacac tcagggacag
      241 cccccagact cctgatttat gatgtcacta agcggccctc aggggtctcg gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tcaccatctc tgggctccag actgaggacg
      361 aggctgatta ttattgttgc tcatatagga gtggaaacac ttggctattc ggcggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004426             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:21329:18257
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004426
VERSION     KCWK01004426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21329:18257"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..419
                     /note="immunoglobulin light chain variable region"
     V_region        89..419
     V_segment       89..384
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70164.1"
                     /translation="DYYCSSYAGSNSLVF"
     J_segment       389..419
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           87 a          150 c          115 g          105 t
ORIGIN      
        1 acatgggggg cactctcggg acatctccac catggcctgg gatctgctcc tcttcaccct
       61 cctcactcag ggcacaggat cctgggctca ggctgtcctg actcagcctc cctcaatgtc
      121 tgggtctcct ggacagtcgg tcaccatctc ctgcactgga accagcagtg acattggtag
      181 ttataaccgt gtctcctggt accaacatca cccagacaaa gcccccaaag tcatgattta
      241 tgagggcagt cagcggccct caggggtctc tgatcgcttc tctgcctcca agtctggcaa
      301 aacggcctcc ctgaccatct ctgggctcca ggctgaggat gaggctgatt attactgcag
      361 ctcatatgca ggcagcaata gtttggtttt cggcggaggg acccggctaa ccgtcctagg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004427             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:17068:18501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004427
VERSION     KCWK01004427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17068:18501"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70165.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          159 c          114 g          110 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aatcaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggggggggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004428             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:27551:14946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004428
VERSION     KCWK01004428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:27551:14946"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..394
                     /note="immunoglobulin light chain variable region"
     V_region        76..394
     V_segment       76..362
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70166.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       363..394
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>432
                     /gene="IGLC"
BASE COUNT           85 a          137 c          115 g           95 t
ORIGIN      
        1 acatggggtg tctccaccat ggcctggact cctctctggc tcaccctcct cagtctttgc
       61 acaggttcta tggtttcttc tgagctgact caggaccctg cagtgtctgt ggccttgggg
      121 cagacagtca ggattacctg ccaaggagac agcctcagaa gctcttatgc aaactggtac
      181 caacagaggc caggccaggc ccctgtgctg gtcgtctatg gtaacaacta ccggccctca
      241 gggatcccag agcgattctc tggctcctac tcccgaaaca cagcttcctt gaccatcact
      301 ggggctcagg tggaagatga ggctgactat tactgtgact cctgggacag cagcggaacc
      361 caattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      421 actctcttcc cg
//
LOCUS       KCWK01004429             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:14186:15377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004429
VERSION     KCWK01004429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14186:15377"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70167.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          143 c          131 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga attgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tctattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgt cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004430             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:18380:19972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004430
VERSION     KCWK01004430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:18380:19972"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..431
                     /note="immunoglobulin light chain variable region"
     V_region        86..431
     V_segment       86..394
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70168.1"
                     /translation="DYYCQVFDSSTVLF"
     J_segment       395..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           91 a          158 c          114 g          106 t
ORIGIN      
        1 acatggggga gaggtagccg tgtccaccat ggccctgact cctctcctcc tcctgctcct
       61 ctctcactgc acaggttccc tctcccagcc tgtgctgact cagccaccct ccctgtctgc
      121 atccccggga gcatcggcca gactcccctg caccctgagc agtgacctca gtgttggtaa
      181 taaaaacatg tactggtacc aacagaagcc agggagcgct cccaggttat tcctgtacta
      241 ctactccgac tcagacaagc agctgggacc tggggtcccc aatcgagtct ctggctccaa
      301 ggagacctca actaacacag cgtttttgct catctctggg ctccagcctg aggacgaggc
      361 cgattattac tgtcaggtgt ttgacagtag tactgtgtta ttcggaggag ggacccgact
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004431             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:15628:13016
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004431
VERSION     KCWK01004431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:15628:13016"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..417
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70169.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       418..454
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           93 a          158 c          132 g          109 t
ORIGIN      
        1 acatgggggg gtgaagcgca gcttcagctg tgggtacaga aggcaggact caggacaatc
       61 tccagcatgg cctggttccc tctcgtcctc accctcctca ctcactgtcc agggtcctgg
      121 gcccagtctg tgctgactca gcctccctca gcgtctgagg ccgccaggaa cagtgtcgcc
      181 atctcctgtt ctggaggcag ctccaacatc ggaagtcata gtgtatcctg gtaccagcag
      241 ctcccaggaa cagctcccaa actcctcatc tattatgatg atcaacgagc ctcaggtgtc
      301 tctggccgat tctctggctc caggtctggc acgtcagcct ccctggccat cagtgggctc
      361 cagaccgagg atgaggctga ttattactgc gcagcatggg atgatagcct gagaggttac
      421 atcttcggtg atgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCWK01004432             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:7921:14040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004432
VERSION     KCWK01004432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7921:14040"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70170.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          163 c          120 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cccctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004433             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:10520:6232
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004433
VERSION     KCWK01004433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10520:6232"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70171.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           98 a          142 c          120 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaagaatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tccagatcat
      241 ctatgaggac agtaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggaa gatgaagttg actactactg
      361 cttctcaaca gacaccagtg gtaatcgggt attcggcgga gggacccgtc taatcgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004434             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10806:14327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004434
VERSION     KCWK01004434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10806:14327"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70172.1"
                     /translation="DYYCQSADTSGNHPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          107 a          135 c          121 g          100 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgaac tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagcaatact
      181 ggaaaaaaaa tatgctcagt ggttccagaa gaagccaggc caggccccta tcttggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacagtt tccttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagca gacaccagtg gtaatcatcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004435             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:24363:3742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004435
VERSION     KCWK01004435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:24363:3742"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70173.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          163 c          109 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagttgcac cttgaacagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacta ctcagactca agtaagcacc aggcctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgacgctga ctattactgt gccacatggc acagcagcgc ttcttacatc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004436             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:10193:10064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004436
VERSION     KCWK01004436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10193:10064"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70174.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          156 c          124 g          106 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc caccaggaag agtgtcacca tctcctgttc
      181 tggaagcaga tccaacatcg gaaggaatag tgtatcctgg taccagcagc tcccaggcac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agcgggctcc agaccgagga
      361 tgaggctgac tattactgcg cagcatggga tgatagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcatcgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01004437             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:12717:19002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004437
VERSION     KCWK01004437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12717:19002"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70175.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           89 a          153 c          123 g          104 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtccagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaacag tgtcgccatc tcctgttctg gaggcagctc
      181 caacatcgga agtcatagtg tatcctggta ccagcagctc ccaggaacag ctcccaaact
      241 cctcatctat tatgatgatc aacgagcctc aggtgtctct ggccgattct ctggctccag
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcatgggatg atagcctgag aggttacatc ttcggtgatg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004438             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:24370:8371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004438
VERSION     KCWK01004438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24370:8371"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..268
                     /note="immunoglobulin light chain variable region"
     V_region        7..268
     V_segment       7..232
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <196..>240
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70176.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       233..268
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        269..>306
                     /gene="IGLC"
BASE COUNT           65 a           95 c           77 g           69 t
ORIGIN      
        1 acatggggaa ccagcagtga catcggtggt tataactatg tctcctggta ccaacagcat
       61 ccaggcacag cccccaaagt catgatttat gaggtcagta agcggccctc aggggtctct
      121 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag
      181 gctgaggacg aggctgatta ttactgcagc tcatatacag gcatcaacag ttacatcttc
      241 ggtggtggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      301 ttcccg
//
LOCUS       KCWK01004439             314 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:7935:2153
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004439
VERSION     KCWK01004439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 314)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7935:2153"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..276
                     /note="immunoglobulin light chain variable region"
     V_region        7..276
     V_segment       7..239
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <201..>248
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70177.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       240..276
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        277..>314
                     /gene="IGLC"
BASE COUNT           69 a           96 c           82 g           67 t
ORIGIN      
        1 acatggggat gacctgccaa ggagacagcc tcaaaaccta ttatgcaagc tggtaccagc
       61 agaagccagg ccaggtccct gtgctggtca tctatggtaa caactaccgg ccctcaggga
      121 tcccaggccg attctctgtc tcctggtcag gaaacacagg ttccttgacc atcactgcgg
      181 ctcaggtgga agatgaggct gactattact gtaagtcctg ggacagcagt ggtacccatt
      241 acatcttcgg tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg
      301 tcactctgtt cccg
//
LOCUS       KCWK01004440             401 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18613:10743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004440
VERSION     KCWK01004440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 401)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18613:10743"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    33..363
                     /note="immunoglobulin light chain variable region"
     V_region        33..363
     V_segment       33..327
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <291..>335
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70178.1"
                     /translation="VYYCCSYTTGSTYIF"
     J_segment       328..363
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        364..>401
                     /gene="IGLC"
BASE COUNT           73 a          131 c           99 g           98 t
ORIGIN      
        1 acatgggcac tcaaggcaca ggatcctggg ctcagtctgc cccgactcag cctccctctg
       61 tgtctgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc actgacgttg
      121 gtggttatga ctctgtctcc tggtaccaaa agtacccagg caaagccccc aaactcatga
      181 tttatggtgt cagtcatcgg ccctcagggg tctctgatcg cttctctggc tccaagtctg
      241 gcaacacggc ctccctgacc atctctgggc tccaggctga ggacgaggct gtttattact
      301 gttgttcata tacaaccggt agcacttaca tcttcggtgg tgggacccgg ctcaccgtcc
      361 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01004441             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:13864:13442
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004441
VERSION     KCWK01004441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13864:13442"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70179.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          156 c          127 g          112 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggagatt attatgtgca gtggtaccag caccttccag
      241 gaacggcccc cagactcctc atctatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggaacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag tttgattgct gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004442             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16558:5211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004442
VERSION     KCWK01004442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16558:5211"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70180.1"
                     /translation="DYYCHVWDMNSHHLLF"
     J_segment       392..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          139 c          136 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcaggc
      121 accctcgatt tcagtgtccc ccggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 gtatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcatgtgtgg gacatgaata gtcatcatct attattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004443             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:14632:15673
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004443
VERSION     KCWK01004443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14632:15673"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..435
                     /note="immunoglobulin light chain variable region"
     V_region        102..435
     V_segment       102..398
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70181.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       405..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           84 a          163 c          127 g           99 t
ORIGIN      
        1 acatggggtc agcagagccc tgaggagtct gcaccatggc ctggacccca atcctcctcc
       61 tcctcctcac tctcctcctt cactgcacag ggtctctctc ccagcctgtg gtgactcagt
      121 cgtcctctgc ctctgcctcc ctgggagcct cggtcaagct cacctgcact ctgagcggtg
      181 ggcacagcga ctacaccatc gcatggcatc agcagcagca agggaaggcc cctcggtatt
      241 tgatgtggct taaaagtgat ggcagccaca gcaaggggga cgggatccct gatcgcttct
      301 ccggctccag ctccggggct gagcgctacc tcaccatctc caacctccag tctgaggatg
      361 aggctgatta ttactgtcag acctgggaga ctggcattca ggtgttcggc ggagggaccc
      421 ggctaaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004444             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:23787:16670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004444
VERSION     KCWK01004444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:23787:16670"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..265
                     /note="immunoglobulin light chain variable region"
     V_region        1..265
     V_segment       1..228
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70182.1"
                     /translation="DYYCQVWDSSSDHWIF"
     J_segment       229..265
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           66 a           88 c           91 g           58 t
ORIGIN      
        1 acatgggggg gagacaacat tggaagtaaa tatgtgcact ggtaccagca gaggccaccg
       61 caggcccctg tgcaagtcat ctatactgat agcagacggc cctcagggat ccctgagcga
      121 ttctctggct ccaactcagg gaacaccgcc accctgacca tcagcgcggt cgaggccggg
      181 gatgaggctg actattactg tcaggtgtgg gacagtagta gtgatcattg gatattcggc
      241 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      301 ccg
//
LOCUS       KCWK01004445             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:11045:9325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004445
VERSION     KCWK01004445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11045:9325"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..402
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70183.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       403..439
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           89 a          162 c          118 g          108 t
ORIGIN      
        1 acatgggggg cctcagaggt agccgtgtcc accatggccc tgactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc accctccctg
      121 tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagtagtga cctcagtgtt
      181 ggtagtaaaa acatctactg gtaccagctg aagccaggga gcgctcccag gtcattcctg
      241 tactactact ccgactcaga caagcagctg ggacctgggg tccccaatcg agtctctggc
      301 tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctgggctcca gcctgaggac
      361 gaggccgatt attactgtca ggtctatgac agtagtgcta atgtgttatt cggaggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004446             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:9972:7476
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004446
VERSION     KCWK01004446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9972:7476"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70184.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          150 c          115 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01004447             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:5777:6521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004447
VERSION     KCWK01004447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:5777:6521"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70185.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       411..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          157 c          129 g          106 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtatcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat cttttataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtcc ggtattcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004448             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:23119:14629
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004448
VERSION     KCWK01004448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:23119:14629"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70186.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       414..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           94 a          157 c          129 g          108 t
ORIGIN      
        1 acatggggga agcgcagctt cagctgtggg tacagaaggc aggactcagg acaatctcca
       61 gcatggcctg gttccctctc gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc
      121 agtctgtgct gactcagcct ccctcagcgt ctgaggccgc caggaacagt gtcgccatct
      181 cctgttctgg aagcagctcc aacatcggaa gtcatagtgt atcctggtac cagcagctcc
      241 caggaacagc tcccaaactc ctcatctatt atgatgatca acgagcctcg ggtgtctctg
      301 accgattctc tggctccagg tctggcacgt cagcctccct ggccatcagt gggctccaga
      361 ccgaggatga ggctgattat tactgcgcag catgggatga tagcctgaga ggttacatct
      421 tcggtgatgg gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCWK01004449             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:21597:3997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004449
VERSION     KCWK01004449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21597:3997"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70187.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          147 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccacca caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004450             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:2790:14537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004450
VERSION     KCWK01004450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:2790:14537"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..343
                     /note="immunoglobulin light chain variable region"
     V_region        13..343
     V_segment       13..308
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70188.1"
                     /translation="DYYCSSYGGRNTLFF"
     J_segment       313..343
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>381
                     /gene="IGLC"
BASE COUNT           76 a          119 c           97 g           89 t
ORIGIN      
        1 acatgggggg ctcaggctgc cccgactcag actccctctg tgtccgggtc tcctggacag
       61 tcggtcacca tctcctgcac tggaaccagc agtgatattg ggtattatca tgctgtgtct
      121 tggtaccagc atcatccagg caaagccccc aaactcatga tttatgaggt caataaacgg
      181 cccgcagggg tctctgatcg cttctctggc tccaagtctg gcaacacggc ctccctgacc
      241 atctctgggc tccagactga ggatgaggct gattattact gcagctcata tggaggcaga
      301 aacactttat tcttcgcagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      361 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004451             403 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:16964:6270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004451
VERSION     KCWK01004451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 403)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16964:6270"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    41..365
                     /note="immunoglobulin light chain variable region"
     V_region        41..365
     V_segment       41..328
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <290..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70189.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       330..365
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>403
                     /gene="IGLC"
BASE COUNT           81 a          118 c          120 g           84 t
ORIGIN      
        1 acatgggggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcaggc
       61 accctcgatt tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      121 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      181 gtatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      241 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      301 tcaggtgtgg gacatgaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      361 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004452             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:6968:6923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004452
VERSION     KCWK01004452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6968:6923"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..258
                     /note="immunoglobulin light chain variable region"
     V_region        8..258
     V_segment       8..221
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <183..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70190.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       222..258
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           62 a           93 c           73 g           68 t
ORIGIN      
        1 acatgggcaa catcggaagt tataatgtgt cctggtacca gcagctccca ggaacagctc
       61 ccaaactcct catctattat aatgatcaac gagcctcagg tgtctctgac cgattctctg
      121 gctccaagtc tggcacgtca gcctccctgg ccatcagtgg gctccagacc gaggatgagg
      181 ctgattatta ctgcgcagca tgggatgata gcctgagcgg ttacatcttc gctgctggga
      241 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004453             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:15655:9624
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004453
VERSION     KCWK01004453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:15655:9624"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70191.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       415..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          157 c          127 g          113 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggagat tattatgtgc agtggtacca gcagcttcca
      241 ggaacggccc ccaaactcct catctctgaa aatcataagc gaccctcagg ggtttctgat
      301 cgcttctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagta gtttgagtgc tgtattattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004454             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10337:13353
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004454
VERSION     KCWK01004454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10337:13353"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70192.1"
                     /translation="DYYCQVFDDSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          160 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata caacgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacga tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004455             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:11202:15696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004455
VERSION     KCWK01004455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11202:15696"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70193.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>460
                     /gene="IGLC"
BASE COUNT           94 a          144 c          123 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaagatc acctgctctg gagatgcact
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 cgatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 cacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004456             495 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:22174:14824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004456
VERSION     KCWK01004456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 495)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22174:14824"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..457
                     /note="immunoglobulin light chain variable region"
     V_region        109..457
     V_segment       109..420
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70194.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       421..457
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        458..>495
                     /gene="IGLC"
BASE COUNT           93 a          169 c          123 g          110 t
ORIGIN      
        1 acatgggggc ccaaccctgg gtctgtggcc tcagaggtag ccgtgtccac catggccctg
       61 actcctctcc tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg
      121 actcagccac cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg
      181 agcagtgacc tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc
      241 gctcccaggt cattcctgta ctactactcc gactcagaca agcagctggg acctggggtc
      301 cccaatcgag tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct
      361 ggactccagc ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat
      421 gtgttattcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      481 gtcactctct tcccg
//
LOCUS       KCWK01004457             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:17085:12925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004457
VERSION     KCWK01004457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17085:12925"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70195.1"
                     /translation="DYYCAMWHNSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          160 c          112 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acaacagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004458             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:14518:18923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004458
VERSION     KCWK01004458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14518:18923"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..407
                     /note="immunoglobulin light chain variable region"
     V_region        87..407
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70196.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       372..407
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>446
                     /gene="IGLC"
BASE COUNT           92 a          141 c          115 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aagatcacct gctctggaga tgcacttcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcgat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gcagtggtta tggcttattc ggaggaggga cccggctgac cgtcctacgt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004459             498 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:18838:12961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004459
VERSION     KCWK01004459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 498)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18838:12961"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..460
                     /note="immunoglobulin light chain variable region"
     V_region        112..460
     V_segment       112..420
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <388..>432
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70197.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       423..460
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        461..>498
                     /gene="IGLC"
BASE COUNT          102 a          155 c          122 g          119 t
ORIGIN      
        1 acatggggac cgcagcccga ttgtgactct tctggcaaag atccctgaaa aatttgaccc
       61 tggtttctgc cttagcaccc aataatgtct gtgtttgcag gttccctctc caagcctatg
      121 ctgactcagc cggcctccct ctcagcatct cctggagcat cagccagtct cacatgcacc
      181 ttcagcggtg gcatcaatgt tgctggctac cacatacact ggtaccagca gaagtcaggg
      241 agtcctcccc ggtatcttct aagatacaaa tcagactcgg atcagggcca gggctctgga
      301 gtccccagcc gcttctctgg atccaaagat gcttcagcga acacggggat tttacacgtc
      361 tctgggctcc agtctgagga tgaggctgac tattactgtg ccattgggca cagcagcggt
      421 gattacatct tcggtgctgg gacccggctc accgtcctag gtcagcccaa ggcttccccc
      481 acggtcactc tgttcccg
//
LOCUS       KCWK01004460             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:2500:10559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004460
VERSION     KCWK01004460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:2500:10559"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..388
                     /note="immunoglobulin light chain variable region"
     V_region        58..388
     V_segment       58..353
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <316..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70198.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       358..388
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           81 a          137 c          108 g          100 t
ORIGIN      
        1 acatgggggg ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag
       61 gctgccccga ctcagactcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc
      121 tgcactggaa ccagcagtga tattgggtat tatcatgctg tgtcttggta ccagcatcat
      181 ccaggcaaag cccccaaact catgatttat gaggtcaata aacggcccgc aggggtctct
      241 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag
      301 actgaggatg aggctgatta ttactgcagc tcatatggag gcagcaatag tttattcttc
      361 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      421 ttcccg
//
LOCUS       KCWK01004461             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:15615:7118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004461
VERSION     KCWK01004461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:15615:7118"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70199.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          164 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagatggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004462             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:14196:3180
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004462
VERSION     KCWK01004462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14196:3180"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70200.1"
                     /translation="NYYCCSYTTSGTYVF"
     J_segment       399..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          159 c          116 g          111 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggtcata actctgtctc ctggtaccaa caaaacccag gcaaagcccc
      241 caaactcatg atttatggtg tcagtaatcg gccctctggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcgacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 taattattac tgttgttcat atacaaccag tggcacttac gtcttcggtg ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01004463             409 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:3896:12548
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004463
VERSION     KCWK01004463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 409)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 409)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:3896:12548"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    213..371
                     /note="immunoglobulin light chain variable region"
     V_region        213..371
     V_segment       213..333
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <296..>343
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70201.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       335..371
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        372..>409
                     /gene="IGLC"
BASE COUNT           77 a          130 c          121 g           81 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggtca cgcacgaagg gagcaccgtg
      181 gagaagacag tggcccctgc agaatgttca taggttccct gagcgaatct ctggctccaa
      241 atcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      301 ttactgtcag gtgtgggaca caagtcttga tcacggctta ttcggaggag ggacccggct
      361 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004464             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:20033:17374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004464
VERSION     KCWK01004464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20033:17374"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70202.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          141 c          134 g          100 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcgcagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg aggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctaagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actactattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggttttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004465             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:17597:17692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004465
VERSION     KCWK01004465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17597:17692"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70203.1"
                     /translation="LYYCCSYTTSSTYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          161 c          114 g          113 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcactgac gttggtggtt ataactctgt ctcctggtac caacaggacc caggcaaagc
      241 ccccaaactc atcatttatg gtgtcagtaa tcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctctttat tactgttgtt catatacaac cagtagcact tacatcttcg gtactgggac
      421 ccggctaacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004466             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:2347:9407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004466
VERSION     KCWK01004466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:2347:9407"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..255
                     /note="immunoglobulin light chain variable region"
     V_region        7..255
     V_segment       7..216
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <183..>227
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70204.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       221..255
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        256..>293
                     /gene="IGLC"
BASE COUNT           65 a           86 c           71 g           71 t
ORIGIN      
        1 acatggggat attctggtac cagcagaagc cagggagtcc tccccggtat cttcttaact
       61 accacacaga ctcagataaa caccaggact ctggagtccc cagccgcttc tttggatcca
      121 aagatgctcc ggccaatgca gggattttac tcatctctgg gctccagtct gaggatgagg
      181 ctgactatta ctgtatgatt tggcacaaca atgcttatgt cttattcgga ggagggaccc
      241 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004467             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:18910:24447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004467
VERSION     KCWK01004467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18910:24447"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..420
                     /note="immunoglobulin light chain variable region"
     V_region        118..420
     V_segment       118..386
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70205.1"
                     /translation="DYYCSSYEGTNSFIF"
     J_segment       387..420
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           87 a          153 c          118 g          100 t
ORIGIN      
        1 acatgggggg ctggggtctc aggaggcagc gctctcagga cgtctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggacc ctgggctcag gctgccctga
      121 ctcagcctcc cggacagtcg gtcaccatct cctgcacggg aaccagcagt gacatcggtg
      181 gttataacta tgtctcctgg taccagcagc acccaggcaa agcccccaaa ctcatgattt
      241 atgatgtcag taagcggccc tcaggggtct ctgatcgctt ctctggctcc aaatctggca
      301 acacggcctc cctgaccatc tctgggctcc aggctgagga tgaggctgat tattactgca
      361 gctcatatga aggcaccaac agtttcatct tcggtgttgg gacccggctc accgtactag
      421 gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01004468             383 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:21444:2122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004468
VERSION     KCWK01004468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 383)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 383)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:21444:2122"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..345
                     /note="immunoglobulin light chain variable region"
     V_region        8..345
     V_segment       8..308
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <273..>317
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70206.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       309..345
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        346..>383
                     /gene="IGLC"
BASE COUNT           80 a          125 c           88 g           90 t
ORIGIN      
        1 acatggggac ccagccaacc tccctctcag catctccggg agcatcagcc agactcagct
       61 gcacctttag cagtggcatc aatgttggta gttacagcat attctggtac cagcagaagc
      121 cagggagtcc tccccggtac cttctctact actactcaga ctcaagtaaa caccagggct
      181 ctggagtccc cagccgcttc tctggatcca aagatgcttc ggccaatgca ggccttttac
      241 tgatctctgg gctccagtct gaagatgagg ctgactatta ctgtgccata tggcacagca
      301 gcgcttctta cttcttcggt actgggaccc ggctcaccgt cctaggtcag cccaaggctt
      361 cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004469             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:9119:12631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004469
VERSION     KCWK01004469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:9119:12631"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70207.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          162 c          119 g          108 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcaactgcac cttgagcagt ggcgtcaatg
      181 tgggtagtta cagcatattc tggtaccagc agcagccagg gagtcctccc cggtaccttc
      241 tgtactacca gtcagactca aggaagcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc tgttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccctatggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004470             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:19028:7682
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004470
VERSION     KCWK01004470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19028:7682"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70208.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           93 a          164 c          120 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca accagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcattttt gatcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggaggtac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004471             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:5234:21286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004471
VERSION     KCWK01004471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:5234:21286"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70209.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctgggttc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004472             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:16160:8206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004472
VERSION     KCWK01004472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16160:8206"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70210.1"
                     /translation="DYFCQVWDSGSDHYIF"
     J_segment       389..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>464
                     /gene="IGLC"
BASE COUNT           86 a          148 c          133 g           97 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag gctctgcgac ctcctatgag ttgactcagc
      121 caccctcggt gtcagcggcc tctggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaactac atatgtgcac tggtaccagc agaagccacc acaggcccct gtgcaggtca
      241 tctttgctga tagcaaacgg ccctcagggg tccctgaccg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactatttct
      361 gtcaggtgtg ggacagtggt agtgatcatt acatcttcgg tgttgggacc cggctcaccg
      421 tcttaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004473             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:10779:17053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004473
VERSION     KCWK01004473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10779:17053"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..388
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70211.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       395..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           87 a          155 c          114 g          114 t
ORIGIN      
        1 acatggggga tctcaggagg cagcgctctc aggacttctc caccatggtc tgggctctgc
       61 tcctcctcac cctcctcact cagggcacag gatcctgggc tcaagctgcc ccgactcagc
      121 ctccctctgt gtccgggtct cctgggcagt cggtcaccat ctcctgcact ggaaccagca
      181 gtgatattgg gtcttataat gctgtgtctt ggtaccaaca acatccaggc aaagcccccc
      241 aactcataat ttttgaggtc aataagcggc cctcaggggt ctctgatcgc ttctctggct
      301 ccaagtctgg caacacggcc tccctgacca tttctgggct ccaggctgag gatgaggctg
      361 attattactg ctgctcatat gtaggcagca acacttacat cttcgatgtt gggacccggc
      421 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004474             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:13367:10039
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004474
VERSION     KCWK01004474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13367:10039"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70212.1"
                     /translation="DYYCQVWGMTSDHPVF"
     J_segment       395..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          140 c          138 g           93 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcataga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgagtcagcc
      121 accctcggtg tcagtgtccc caggagagac ggccaggatc acctgtgggg gagacaaaat
      181 tggaagtgaa gtagtgaatt ggtaccagca gaagccaccg caggccccta tactggtcat
      241 ctatgctgat aacgaacggc ccccagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg ggcatgacta gtgatcatcc ggttttcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004475             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:21778:4164
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004475
VERSION     KCWK01004475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21778:4164"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..408
                     /note="immunoglobulin light chain variable region"
     V_region        90..408
     V_segment       90..376
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70213.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       377..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           88 a          140 c          121 g           97 t
ORIGIN      
        1 acatgggagc agagctctgg ggtgtctcca ccatggcctg gactcctctc tggctcaccc
       61 tcctcagtct ttgcacaggt tctatggttt cttctgagct gactcaggac cctgcagtgt
      121 ctgtggcctt ggggcagaca gtcaggatta cctgccaagg agacagcctc agaagctctt
      181 atgcaaactg gtaccaacag aggccaggcc aggcccctgt gctggtcgtc tatggtaaca
      241 actaccggcc ctcagggatc ccagagcgat tctctggctc ctactcccga aacacagctt
      301 ccttgaccat cactggggct caggtggaag atgaggctga ctattactgt gactcctggg
      361 acagcagcgg aacccaattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004476             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:16614:5297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004476
VERSION     KCWK01004476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16614:5297"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70214.1"
                     /translation="DYYCQVWDTTLDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          148 c          129 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg agagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gttctggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact cttgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004477             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18087:18979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004477
VERSION     KCWK01004477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18087:18979"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70215.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           93 a          152 c          120 g          104 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtcaccatc tcctgttctg gaagcagctc
      181 caacatcgga agtaataatg tgtcctggta ccagcacctc ccaggaacag ctcccaaact
      241 cctcatctat tataatgatc aacgaggctc aggtgtctct gaccgattct ctggctccaa
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcgtgggatg ataggctgag cagttacatc ttcgctgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004478             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:14288:7159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004478
VERSION     KCWK01004478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14288:7159"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..449
                     /note="immunoglobulin light chain variable region"
     V_region        125..449
     V_segment       125..406
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70216.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       415..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           93 a          154 c          143 g           97 t
ORIGIN      
        1 acatgggatc aacgcagagt acatgggggt ctgggtctca ggaggcagca ttgacggtgc
       61 ctcagccatg gcctggaccc ttctcctcct cggcctcctc gctcactgca caggctctgc
      121 gacctcctat gagctgactc agccaccctc ggtgtcagcg gcctcaggac agacggccag
      181 gatcacctgt gggggagaca acattggaac taaatatgtg cactggtacc agcagaagcc
      241 agcgcaggcc cctgtgttgg tcatctatgc tgataccaga cggccctcag ggatccctga
      301 gcgattctct ggctccaact ccgggaacac cgccaccctg accatcagcg gggtcgaggc
      361 cgggtatgag gctgactatt tctgtcaggt gtgggacgat agtagtgatc atccggtatt
      421 cggcggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01004479             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:20657:11489
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004479
VERSION     KCWK01004479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20657:11489"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70217.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       407..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          153 c          129 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgct
      181 ctgggagcag ctccaacatc ggggcgggtt tttatgtttc ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctttgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattat tgttcatcat gggaaagcag cctgaattgg gtattcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004480             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:12360:10685
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004480
VERSION     KCWK01004480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12360:10685"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70218.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       395..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          142 c          139 g           97 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgc ggcctcctat gcggtgactc
      121 agccacgctc agtgtccgtg tccccaggac aggcggccag gatcacctgt gggggagaca
      181 acattggaag taaaagtgtc cagtggtacc agcagacgcc accgcaggcc cctgtactgg
      241 tcatttatgg tgatagggaa cggccctcag ggatccctga acgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggatagt agtagtaaat atgtcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004481             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:15465:12007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004481
VERSION     KCWK01004481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15465:12007"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70219.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          163 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgccc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcagctaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004482             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:10776:3582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004482
VERSION     KCWK01004482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:10776:3582"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70220.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           91 a          147 c          127 g           96 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtcaaag tgtgcactgg taccagcaca agccaccgca ggcccctgta ctggtcatct
      241 tttattatac cgaacggccc tcaggaatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cacaactatt gatcacggct tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004483             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:12590:16201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004483
VERSION     KCWK01004483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12590:16201"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..303
                     /note="immunoglobulin light chain variable region"
     V_region        8..303
     V_segment       8..267
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70221.1"
                     /translation="DYYCAIWHSSAYIF"
     J_segment       268..303
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           76 a          104 c           81 g           80 t
ORIGIN      
        1 acatgggagg cagactcagc tgcaccttga gcagtgacat caatgttggt acttacagca
       61 tattctggta ccagcagaag ccagggagtc ctccccggta ccttctgtac tacaactcag
      121 actcaagtaa acaccagggc tctggagtcc ccagccgctt ctctggatcc aaagatgctt
      181 cagccaatgc aggactttta ctgatctctg gtctccggtc tgaagatgag gctgactatt
      241 actgtgccat atggcacagc agcgcttaca tcttcggtac tgggacccgg ctcaccgtcc
      301 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01004484             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:8463:6586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004484
VERSION     KCWK01004484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:8463:6586"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..400
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70222.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           89 a          151 c          129 g          108 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg tcaccatctc ctgcactggg
      181 agcagctcca acatcggggc gggtttttat gtatcctggt accagcagtt cccaggaaaa
      241 gcccccaagc tcctcatctt tgaaaataac aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggttc ctcagcctcc ctgaccatca ctggactcca atctgaggat
      361 gaggctgatt attattgttc atcatgggaa agcagcctga attgggtatt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004485             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:19768:13978
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004485
VERSION     KCWK01004485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19768:13978"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..403
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70223.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          157 c          122 g          108 t
ORIGIN      
        1 acatgggggg ctgggatctc acgaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccccga
      121 ctcagactcc ctctgtggcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tattgggtat tatcatgctg tgtcttggta ccaacatcat ccaggcaaag
      241 cccccaaact catgatttat gaggtcaata aacggcccgc aggggtctct gatcgcttct
      301 ctggctccaa gtccggcaac acggcctccc tgaccatctc tgggctccag actgaggatg
      361 aggctgatta ttactgcagc tcatatgcag gcagcaacac tttgttcttc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004486             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:25366:9846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004486
VERSION     KCWK01004486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:25366:9846"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70224.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          145 c          140 g           93 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccag cgcacgcccc tgtgctggtc
      241 atctatgcta atagcgaacg gccctcaggg atccctgggc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg ggggtgaggc tgactattac
      361 tgtcaggtgt gggacatgcg tagtgatcaa ccgctattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004487             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:16595:15198
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004487
VERSION     KCWK01004487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16595:15198"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..444
                     /note="immunoglobulin light chain variable region"
     V_region        111..444
     V_segment       111..407
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70225.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       410..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          159 c          130 g          105 t
ORIGIN      
        1 acatggggat tcctggctgt ggctcaggaa gcagagcctg gagcgtctcc accatggcct
       61 gggctccact cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttctgt
      121 tcacgcagcc ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgtaccc
      181 gcagcagagg caacattgac aatagttatg tgcagtggta ccagcagcgc ccgggcagtg
      241 ccccgaccac agtgatttac agagatgacc aaagagcctc tggggtccct gatcggttct
      301 ctggctccat cgacagctcc tccaactctg cctccctcac catctctggg ctgaagtctg
      361 aggacgaggc tgactactac tgtcagtcta ctgatggcaa ctacaatcgg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004488             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:19189:6776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004488
VERSION     KCWK01004488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19189:6776"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70226.1"
                     /translation="DYCCQSYDSSLSVVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           87 a          155 c          130 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccag cagcttccag
      241 gagcggcccc caaactcctc atctatgaaa atgataaacg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct gattcctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattgc tgccagtcct atgacagcag cttgagtgtt gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004489             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:19288:7858
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004489
VERSION     KCWK01004489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19288:7858"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..266
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <230..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70227.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       268..305
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           69 a          104 c           90 g           80 t
ORIGIN      
        1 acatgggggg gcgcccgggc agagggtcac cctctcctgc actgggagca gctccaacat
       61 tggagattat tatgtgcagt ggtaccagca gcttccagga acggccccca aactcctcat
      121 ctatgaaaat aataagcgac cctcaggggt ttctgatcga ttctctggct cccagtctgg
      181 tacctcagcc tccctgacca tcactggact ccagtctgac gatgaggctg attattactg
      241 tcagtcctat gatagcagcc tgagtgttgt gttattcgga ggagggaccc ggctgaccgt
      301 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004490             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:9250:12497
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004490
VERSION     KCWK01004490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9250:12497"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..255
                     /note="immunoglobulin light chain variable region"
     V_region        8..255
     V_segment       8..219
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <183..>227
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70228.1"
                     /translation="DYYCCYHTTSGSYIF"
     J_segment       220..255
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        256..>293
                     /gene="IGLC"
BASE COUNT           53 a           98 c           72 g           70 t
ORIGIN      
        1 acatgggcgt tgctggttat cactctgtct cctggtacca acagccccca ggcaaagccc
       61 ccaaactcat gatttatggt gtcagtcatc ggcccgcagg ggtctctgct cgcttctctg
      121 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      181 ctgattatta ctgttgttac cacacaacca gtggcagtta catcttcgat ggtgggaccc
      241 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004491             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:8157:7700
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004491
VERSION     KCWK01004491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:8157:7700"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70229.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           88 a          161 c          120 g          107 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc gtcaatgtgg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctgt
      241 actaccagtc agactcaagg aagcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggctgt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc ctctggcaca gcagcgcttc ttgcatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004492             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:9150:12890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004492
VERSION     KCWK01004492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9150:12890"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..387
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70230.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       388..419
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           90 a          142 c          126 g           99 t
ORIGIN      
        1 acatggggtg ggctcagaag cagagctctg gggtgtctcc accatggcct ggactcctct
       61 ctggctcacc ctcctcagtc tttgcacagg ttctatggtt tcttctgagc tgactcagga
      121 ccctgcagtg tctgtggcct tggggcagac agtcaggatt acctgccaag gagacagcct
      181 cagaagctct tatgcaaact ggtaccaaca gaggccaggc caggcccctg tgctggtcgt
      241 ctatggtaac aactaccggc cctcagggat cccagagcga ttctctggct cctactcccg
      301 aaacacagct tccttgacca tcactggggc tcaggtggaa gatgaggctg actattactg
      361 tgactcctgg gacagcagcg gaacccaatt cggaggaggg acccggctga ccgtcctagg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004493             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:10391:10100
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004493
VERSION     KCWK01004493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:10391:10100"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70231.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          144 c          142 g           91 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcatcga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tggaagtgaa gttgtgaact ggtaccagcg gaagccagcg caggcccctg tgctggtcat
      241 ctatgctgat agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg ggtgaggctg actattactg
      361 tcaggtgtgg gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004494             318 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:24042:10594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004494
VERSION     KCWK01004494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 318)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24042:10594"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..280
                     /note="immunoglobulin light chain variable region"
     V_region        7..280
     V_segment       7..241
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>252
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70232.1"
                     /translation="VYYCAIGHSSGLYIF"
     J_segment       243..280
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        281..>318
                     /gene="IGLC"
BASE COUNT           62 a           95 c           86 g           75 t
ORIGIN      
        1 acatggggtg gcatcaatgt tgctgtctac cacgtacact ggtaccagca gaagccaggg
       61 agtccccccc ggtatcttct gaggtacaaa tcagactcag ataagggcca gggctctggg
      121 gtccccagcc gcttctctgg atccagtaat gcttcagcga acacagggat tttacgcatt
      181 tctgggctcc agtctgagga tgaggctgtc tattactgtg ccattgggca cagcagcggt
      241 ctttacatct tcggtgctgg gacccggctc accgtcctag gtcagcccaa ggcttccccc
      301 acggtcactc tgttcccg
//
LOCUS       KCWK01004495             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:13454:15152
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004495
VERSION     KCWK01004495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:13454:15152"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..417
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70233.1"
                     /translation="AYYCAAWDDSLRGYIF"
     J_segment       418..454
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           92 a          158 c          133 g          109 t
ORIGIN      
        1 acatgggggg gtgaagcgca gcttcagctg tgggtacaga aggcaggact caggacaatc
       61 tccagcatgg cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg
      121 gcccagtctg tgctgactca gcctccctca gcgtctgagg ccgccaggaa cagtgtcgcc
      181 atctcctgtt ctggaagcag ctccaacatc ggaagtcata gtgtatcctg gtaccagcag
      241 ctcccaggaa cagctcccaa actcctcatc tattatgatg atcaacgagc ctcgggtgtc
      301 tctgaccgat tctctggctc caggtctggc acgtcagcct ccctggccat cggtgggctc
      361 cagaccgagg atgaggctgc ttattactgc gcagcatggg atgatagcct gagaggttac
      421 atcttcggtg atgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCWK01004496             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:9547:17013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004496
VERSION     KCWK01004496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9547:17013"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70234.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       403..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           83 a          163 c          127 g           98 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtggt gactcagtcg
      121 tcctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcggtggg
      181 cacagcgact acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggtatttg
      241 atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctga tcgcttctcc
      301 ggctccagct ccggggctga gcgctacctc accatctcca ccctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggagact ggcattcagg tgttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004497             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:15373:15013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004497
VERSION     KCWK01004497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15373:15013"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..424
                     /note="immunoglobulin light chain variable region"
     V_region        97..424
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70235.1"
                     /translation="DYYCAAWDDSLRSPIF"
     J_segment       395..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>465
                     /gene="IGLC"
BASE COUNT           90 a          154 c          119 g          102 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgagctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaat
      181 attggcagta attctgtata ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctattata gtaatcagcg accctcaggg gtccctgacc gagtctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgacag cctgagaagt ccgatattcg gcggagggac ccggctgacc
      421 gtcccaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004498             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:11590:10264
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004498
VERSION     KCWK01004498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:11590:10264"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..230
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <197..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70236.1"
                     /translation="DYYCSSWESSLNWVL"
     J_segment       232..269
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           61 a           94 c           79 g           73 t
ORIGIN      
        1 acatgggggg agcagctcca acatcggggc gggtttttat gtgtcctggt accagcagtt
       61 ccctggaaca gcccccaaac tcctcatctt tgaaaataat aagcgaccct caggggtttc
      121 tgaccgattc tctggctcca agtctggttc ctcagcctcc ctgaccatca ctggactcca
      181 gtctgaagat gaggctgatt attactgctc atcttgggaa agcagcctga attgggtact
      241 cggcggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01004499             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:24530:7847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004499
VERSION     KCWK01004499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24530:7847"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70237.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          147 c          130 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgtcccctcg gtcactctct tcccg
//
LOCUS       KCWK01004500             497 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:8506:9013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004500
VERSION     KCWK01004500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 497)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 497)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..497
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:8506:9013"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    129..459
                     /note="immunoglobulin light chain variable region"
     V_region        129..459
     V_segment       129..422
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>431
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70238.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       423..459
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        460..>497
                     /gene="IGLC"
BASE COUNT           94 a          157 c          133 g          113 t
ORIGIN      
        1 acatggggga tttgggtgaa gcgcagcttc agctgtgggt acagaaggca ggactcagga
       61 caatctccag catggcctgg ttccctctcg tcctcaccct cctcactcac tgtgcagggt
      121 cctgggccca gtctgtgctg actcagcctc cctcagcgtc tgaggccgcc aggaacagtg
      181 tcgccatttc ctgttctgga agcagctcca acatcggaag tcatagtgta tcctggtacc
      241 agcagctccc aggagcagct cccaaactcc tcatctatta tgatgatcaa cgagcctcag
      301 gtgtctctga ccgattctct ggctccaggt ctggcacgtc agcctccctg gccatcagtg
      361 ggctccagac cgaggatgag gctgattatt actgcgcagc atgggatgat agcctgagag
      421 gttacatctt cggtgctggg acccggctca ccgtcctagg tcagcccaag gcttccccca
      481 cggtcactct gttcccg
//
LOCUS       KCWK01004501             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:16818:10876
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004501
VERSION     KCWK01004501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16818:10876"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70239.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          140 c          140 g           97 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgc ggcctcctat gaggtgactc
      121 agccacgctc agtgtccgtg tcccccggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taaaagtgtg cagtggtacc agcagacgcc accgcaggcc cctgtactgg
      241 tcatttatgg tgatagggaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggatagt agtagtaaat atgtattatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004502             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17646:17736
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004502
VERSION     KCWK01004502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17646:17736"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70240.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           90 a          147 c          129 g           96 t
ORIGIN      
        1 actggggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtcaaa gtgtgcactg gtaccagcac aagccaccgc aggcccctgt actggtcatc
      241 ttttattata ccgaacggcc ctcaggaatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acacaactat tgatcacggc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004503             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:10759:14281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004503
VERSION     KCWK01004503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10759:14281"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..385
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70241.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       387..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           87 a          148 c          121 g          106 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgc ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gcatctgggg cccccgggca gagggtcacc atctcctgct ctgggagcag ctccaacatc
      181 ggggcgggtt tttatgtatc ctggtaccag cagttcccag gaacagcccc caaactcctc
      241 atctttgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggttcctcag cctccctgac catcactgga ctccaatctg aggatgaggc tgattattat
      361 tgttcatcat gggaaagcag cctgaattgg gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004504             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:14757:7357
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004504
VERSION     KCWK01004504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:14757:7357"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..453
                     /note="immunoglobulin light chain variable region"
     V_region        123..453
     V_segment       123..416
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70242.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       417..453
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           91 a          157 c          126 g          117 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactt cacagttcca gggtcctggg
      121 cccagtctgt gctgacgcag ccgccctcag tgtctggggc gcccgggcag agggtcacca
      181 tctcctgcac tgggagcagc tccaacattg gagattattt tgtgcagtgg taccagcacc
      241 ttccaggaac ggcccccaaa ctcctcatct atgaaaataa taagcggccc tcagggattt
      301 ctgatcgatt ctctggctcc cagtttggaa cctcagcctc cctgaccatc actggactcc
      361 agtctgagga tgaggctgat tattactgcc agtcctatga cagcagtttg attgctgtgt
      421 tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      481 ctctcttccc g
//
LOCUS       KCWK01004505             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:9368:7631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004505
VERSION     KCWK01004505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9368:7631"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70243.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>460
                     /gene="IGLC"
BASE COUNT           94 a          142 c          124 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggtcaagatc acctgctctg gagatgcact
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 cgatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004506             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:7828:19284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004506
VERSION     KCWK01004506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7828:19284"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..439
                     /note="immunoglobulin light chain variable region"
     V_region        94..439
     V_segment       94..402
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70244.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       403..439
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           90 a          161 c          117 g          109 t
ORIGIN      
        1 acatggggtg tggcctcaga ggtagccgtg tccaccatgg ccctgactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgactca gccaccctcc
      121 ctgtctgcat ccccgggagc atcggccaga ctcccctgca ccctgagcag tgacctcagt
      181 gttggtaata aaaacatgta ctggtaccaa cagaagccag ggagcgctcc caggttattc
      241 ctgtactact actccgactc agacaagcag ctgggacctg gggtccccaa tcgagtctct
      301 ggctccaagg agacctcaac taacacagcg tttttgctca tctctgggct ccagcctgag
      361 gacgaggccg attattactg tcaggtgttt gacagtagtg ctgtgttatt cggaggaggg
      421 acccgactga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004507             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:9394:17620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004507
VERSION     KCWK01004507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:9394:17620"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70245.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          158 c          127 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgccct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gttgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004508             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:17498:5540
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004508
VERSION     KCWK01004508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17498:5540"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70246.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          158 c          114 g          116 t
ORIGIN      
        1 acatgggggc tgggatctca gcaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcaag ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggatc
      181 catcagtgat attgggtctt ataatgctgt gtcttggtac caacagcatc caggcaaagc
      241 cccccaactc ataatttttg aggtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctgacaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgctgct catatgtagg cagcaacact tacatcttcg atgttgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004509             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:8966:13049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004509
VERSION     KCWK01004509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8966:13049"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70247.1"
                     /translation="DYYCSTYVGSNTYMF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          158 c          121 g          106 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gcgtatgata atgctgtgtc ttggtaccag cagcatccag gcaaggcccc
      241 caaactcatg atttatgacg tcagtaagcg gccctcaggg gtctctgatc gcttctcggg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgactattac tgcagcacat atgtaggcag caacacttac atgttcgatc ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01004510             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:5131:15758
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004510
VERSION     KCWK01004510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:5131:15758"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70248.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          137 c          139 g          100 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 gcaccctcga tttcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtgaa ctggtaccag cagaaggcac cgcaggcccc tgtgttggtc
      241 atgtatgctg atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacatgaa tagtcatcat ctgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004511             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:22978:10501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004511
VERSION     KCWK01004511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:22978:10501"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70249.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       387..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          147 c          118 g          103 t
ORIGIN      
        1 acatgggggg ctcagaagca gaactctggg tcctctccac catggcctgg acccctcccc
       61 tgctcatcct cctcactctc tgcacaggtt ccgtggtttc ctctgagctg actcaggagc
      121 ctgcattgtc tgtggccttg ggacaaacag tcaggatgac ctgccaagga gacagcctca
      181 aaacctatta tgcaagctgg taccagcaga agccaggcca ggtccctgtg ctggtcatct
      241 atggtaacaa ctaccggccc tcagggatcc caggccgatt ctctgtctcc tggtcaggaa
      301 acacaggttc cttgaccatc actgcggctc aggtggaaga tgaggctgac tattactgta
      361 agtcctggga cagcagtggt acccattaca tcttcggtgc tgggacccgg ctcaccgtcc
      421 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01004512             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:6383:4268
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004512
VERSION     KCWK01004512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6383:4268"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70250.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       414..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          162 c          123 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccaacaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctaa tgtcttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004513             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:9929:18174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004513
VERSION     KCWK01004513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9929:18174"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70251.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           91 a          162 c          117 g          110 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggta ataaaaacat gtactggtac caacagaagc cagggagcgc tcccaggtta
      241 ttcctatact actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aactaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcaggtg tttgacagta gtgctgtgtt attcggagga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004514             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:20139:7902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004514
VERSION     KCWK01004514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20139:7902"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70252.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       398..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           93 a          149 c          132 g           98 t
ORIGIN      
        1 acatggggat cctggcttca gaagcagcat ctgggacatg tcagccatgg cctggacgcc
       61 tctcctcctc agcctcctcg ctcactgcac aggctctgtg gcctcctatg agctgactca
      121 gctaccctca gtgtcggtgt ccccaggaca gacagccagc atcacctgct ctggaaataa
      181 attggggaat gtatatgctt actggttcca gcagaagcca ggccaggccc ctgtagtggt
      241 catctacaaa gataccaacc ggccctcagg gatccctgag cgattctctg gctccgactc
      301 agggaacacg gccaccctga ccatcagcag ggtcgaggct ggggatgagg ccgactattt
      361 ttgtgctgca gcctatggca gtggcagcag ctggcagtgg gtattcggcg gagggacccg
      421 gctaatcgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004515             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:5893:18487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004515
VERSION     KCWK01004515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5893:18487"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70253.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       392..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          142 c          137 g           99 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcgat ttcagtgtcc ccaggacaga cggccagggt cacctgtggg ggagacaaca
      181 tcggaggtga agttgtgaat tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tctatgctga tagcgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacgcggc caccctgacc atcagcgggg tcgaggccgg agatgaggct gactattact
      361 gtcaggtgtg ggaccttaat agtcatcatc tcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004516             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:14066:8572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004516
VERSION     KCWK01004516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14066:8572"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70254.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          145 c          132 g           96 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca cagtctctgc gacctcctat gaactgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc agcagaggcc accgcagggc cctgtattgg
      241 tcatctttgc tgatagtaaa cgtccctcag ggatccctga gcgcttctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004517             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:21034:13856
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004517
VERSION     KCWK01004517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21034:13856"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70255.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       414..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          157 c          123 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccggaca gagggtcacc atctcctgca
      181 ttagcagcag ctccaacatc ggggcggctt attatgtatc ctggtaccaa cagttcccag
      241 gaacagcccc caaactcctc atctttgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtccctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattac tgtttagcat gggataccag cctgaattgg atcttcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004518             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:25469:19972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004518
VERSION     KCWK01004518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:25469:19972"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70256.1"
                     /translation="DYSCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          139 c          135 g          103 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattcctg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004519             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:8698:16486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004519
VERSION     KCWK01004519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8698:16486"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70257.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          147 c          130 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccaaca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004520             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:5365:14565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004520
VERSION     KCWK01004520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:5365:14565"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70258.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          161 c          121 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca ggctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004521             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:11955:7252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004521
VERSION     KCWK01004521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:11955:7252"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70259.1"
                     /translation="DYYCQSADSSGYHYIF"
     J_segment       389..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          104 a          135 c          121 g          103 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgaac tgacacagtc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg cagaaatact
      181 ggcaaaaaaa tatgctcagt ggttccagca gaagccaggc caggcccctg tgttggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacagtt accttgacca tcagtggggc ccaggcagag gatgaggctg actattactg
      361 tcaatcagca gacagcagtg gttatcatta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004522             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:12349:6882
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004522
VERSION     KCWK01004522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12349:6882"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70260.1"
                     /translation="DYYCSSYAGSNTHWLF"
     J_segment       410..440
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           88 a          160 c          121 g          109 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac cagctacacc caggcaaagc
      241 ccccaaactc atgatttatg atgtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctgacaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 gactgattat tactgcagct catatgcagg cagcaacact cattggcttt tcggcggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004523             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:26029:8951
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004523
VERSION     KCWK01004523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:26029:8951"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..268
                     /note="immunoglobulin light chain variable region"
     V_region        8..268
     V_segment       8..232
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70261.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       237..268
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        269..>307
                     /gene="IGLC"
BASE COUNT           68 a           98 c           73 g           68 t
ORIGIN      
        1 acatggggga agcagctcca acattggaac taattatgta tactggtacc aacacctccc
       61 aggaacggcc cccaaactcc tcatctatta tagtaatcag cgaccctcag gggtccctga
      121 ccgattctct ggctctaagt ctggcacctc agcctccctg gccatcactg gtctccgatc
      181 tgaggatgag gctgattatt actgtgcagc atgggataac agcctgacca gtccggtatt
      241 cggaggaggg acccggctga ccgtcctaag tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01004524             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:27985:9030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004524
VERSION     KCWK01004524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:27985:9030"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70262.1"
                     /translation="DYYCAAWDDSLRGFIF"
     J_segment       411..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          156 c          126 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggttt catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004525             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:10823:10134
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004525
VERSION     KCWK01004525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10823:10134"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    57..381
                     /note="immunoglobulin light chain variable region"
     V_region        57..381
     V_segment       57..344
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>353
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70263.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       348..381
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        382..>419
                     /gene="IGLC"
BASE COUNT           82 a          126 c          120 g           91 t
ORIGIN      
        1 acatggggac ttttctcctc ctcggcctcc ttgcttactg cacaggctct gcggcctcct
       61 atgatctgac tcaggcaccc tcgatttcag tgtcccccgg acagacggcc aggatcacct
      121 gtgggggaga caacattgga agtgaagttg tgaactggta ccagcagaag ccaccgcagg
      181 cccctgtgtt ggtcatgtat gctgatagcg agcggccctc agggatccct gagcgattct
      241 ctggctccaa atcagggaac acggccaccc tgaccatcag cggggtcgag gccggggatg
      301 aggctgacta ttactgtcag gtgtgggaca tgaatagtca tcatctatta ttcggaggag
      361 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004526             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:17689:19187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004526
VERSION     KCWK01004526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17689:19187"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..248
                     /note="immunoglobulin light chain variable region"
     V_region        8..248
     V_segment       8..214
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70264.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       217..248
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        249..>289
                     /gene="IGLC"
BASE COUNT           60 a           86 c           86 g           57 t
ORIGIN      
        1 acatggggga agtgaagttg tgaactggta ccagcagaag ccaccgcagg cccctgtcct
       61 ggtcatctat gctaataacg aacggccctc agggatccct gagcgattct ctggctccaa
      121 atcagggaac acggccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      181 ttactgtcag gtgtggggcg ttactagtga tcatccctta ttcggaggag ggacccggct
      241 gaccgtccaa ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004527             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:9267:12426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004527
VERSION     KCWK01004527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9267:12426"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70265.1"
                     /translation="DYYCQVYDSSANVVF"
     J_segment       417..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          161 c          126 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaag atgtactggt accagcagaa ggcagggagc gctcccaggt
      241 tatacctcta ctacgactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagccttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtggttttcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004528             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:17563:14615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004528
VERSION     KCWK01004528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:17563:14615"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70266.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agtagtgacc
      181 tcagtgttgg tagtaaaaac atctactggt accagctgaa gccagggagc gctcccaggt
      241 cattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cacaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tctatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004529             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:15577:14236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004529
VERSION     KCWK01004529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:15577:14236"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..389
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70267.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          155 c          112 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag caccttcaac
      181 atcggaagca ataatgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 ctttattata atgatcaacg agcctcaggt gtctctgacc gattctcttg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcatcat gggatgatac cctgagcggc tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004530             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:17638:17482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004530
VERSION     KCWK01004530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17638:17482"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70268.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          152 c          119 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaacagtgtc gccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattatg atgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaggtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagaggt tacatcttcg gtgatgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004531             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:20649:13556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004531
VERSION     KCWK01004531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20649:13556"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70269.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          158 c          120 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtcctgactc agcctccctc aacgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca actccaacat cggaagttat aatgtgtcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004532             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:22061:16131
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004532
VERSION     KCWK01004532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22061:16131"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..382
                     /note="immunoglobulin light chain variable region"
     V_region        58..382
     V_segment       58..345
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <307..>354
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70270.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       346..382
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>420
                     /gene="IGLC"
BASE COUNT           81 a          134 c          115 g           90 t
ORIGIN      
        1 acatggggga cttttctcct cctcggcctc cttgcttact gcacaggctc tgcggcctcc
       61 gatgatctga ctcagccacc ctcggtgtca gtgtccccag gacagacggc caggatcacc
      121 tgtgggggag acaacattgg aagtaagagt gtgcactggt accagcacaa gccaccgcag
      181 gcccctatcc tggtcatcta ttattatacc gaacggccct cggcgatccc tgagcgattc
      241 tctggctcca aatcagggaa caccgccacc ctgaccatca gcggggtcga ggccggggat
      301 gaggctgact attactgtca ggtgtgggac actactattg atcatggctt tttcggagga
      361 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004533             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:14470:19922
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004533
VERSION     KCWK01004533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:14470:19922"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70271.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          162 c          111 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggct
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004534             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:20938:7317
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004534
VERSION     KCWK01004534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20938:7317"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70272.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          148 c          130 g           96 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaagca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004535             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:20626:17786
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004535
VERSION     KCWK01004535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20626:17786"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70273.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          156 c          118 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacgtacac tggtatcagc ggaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc tgggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aatacaggga ttttacacat ctctggtttc cagtctgagg
      361 atgaggctga ctattactgt gccattggcc acggtagcgg tgactacatc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004536             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:11931:16141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004536
VERSION     KCWK01004536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11931:16141"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70274.1"
                     /translation="DYYCQSADSSGNHPFF"
     J_segment       398..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          104 a          137 c          123 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac agtctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actgccaaaa aaatatgctc agtggttcca gcagaagcca ggccaggccc ctgtgttggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgac cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagca gtggtaatca tccgtttttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004537             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:19936:4503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004537
VERSION     KCWK01004537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19936:4503"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..409
                     /note="immunoglobulin light chain variable region"
     V_region        79..409
     V_segment       79..370
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70275.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       372..409
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           82 a          144 c          115 g          106 t
ORIGIN      
        1 acatggggga cagtctccag catggcctgg tctcctctcc tcctcaccct tctcattcac
       61 tgcacagggt cctgggccca gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc
      121 gggcagaggg tcaccatctc ctgcactggg agcagctcca acattggagg ttattatgtg
      181 cagtggtacc aacagcttcc aggaacggcc cccaaactcc tcatctatga aaatgataaa
      241 cgaccctcag gggtttctga tcgattctct ggctcccagt ctgattcctc agcctccctg
      301 accgtcactg gactccagtc tgaggatgag gctgattatt actgccagtc ctatgacagc
      361 agcttgagtg ttgtgttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004538             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:15347:9904
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004538
VERSION     KCWK01004538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15347:9904"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70276.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>460
                     /gene="IGLC"
BASE COUNT           95 a          143 c          123 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaagatc acctgctctg gagatgcact
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 cgatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggagc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004539             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:10896:21485
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004539
VERSION     KCWK01004539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10896:21485"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70277.1"
                     /translation="PEDCQVYDSNAVLF"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          162 c          114 g          104 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg cagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctcta ctactactcc gactcagaca accaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggactg ccaggtgtat gacagtaatg ctgttttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004540             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:18579:11894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004540
VERSION     KCWK01004540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18579:11894"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70278.1"
                     /translation="DYYCQVWDINSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          138 c          136 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcaggc
      121 accctcgatt tcagtgtccc ctggacagac ggccaggatc acctgtgggg aagacaatat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattaata gtcatcatct gttattcgga ggagggaccc ggctggccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004541             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:10603:18807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004541
VERSION     KCWK01004541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:10603:18807"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70279.1"
                     /translation="DYYCCSRSSSSTYVF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           82 a          161 c          119 g          113 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctcgacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac gttggtggtt ataactctgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaagtc atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagt ctgaggacga
      361 ggctgattat tactgttgtt cacgttcaag cagcagcact tacgtcttcg gtcctgggac
      421 ccggctcacc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004542             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:14506:9419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004542
VERSION     KCWK01004542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14506:9419"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70280.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          107 a          137 c          122 g          100 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatacac agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004543             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:20598:15643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004543
VERSION     KCWK01004543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20598:15643"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70281.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          138 c          134 g          103 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtatccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004544             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:24140:9553
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004544
VERSION     KCWK01004544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24140:9553"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70282.1"
                     /translation="DYYCAAWDESLNGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          158 c          125 g          104 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccacga agagtgtcac catctcctgt
      181 tctgggagca gctccaacat cggaagaaat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc gccctggcca tcagcgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgaaagcc tgaacggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004545             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:16564:19148
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004545
VERSION     KCWK01004545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16564:19148"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70283.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          158 c          128 g          107 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctcccgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcagcact cagggacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tattgttgct catataggag tggaaacact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004546             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:17429:11937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004546
VERSION     KCWK01004546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17429:11937"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70284.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          142 c          135 g          102 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaggccac cgcaggcccc tgtgctggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004547             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:7101:23198
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004547
VERSION     KCWK01004547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7101:23198"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..386
                     /gene="IGLV3-35"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70285.1"
                     /translation="DYYCGSWDNSDKRYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          138 c          125 g          108 t
ORIGIN      
        1 acatgggggg tgggctcaga agcagaactc tgggtcgtct ccaccatggc ctggacccct
       61 cccctgctca tcctcctcac tctctgcaca ggttccgtgg tttcctctgg gctgactcag
      121 gagcctgcat tgtctgtggc cttgggacat acagtcagga tgacctgcca aggagacagc
      181 ctcaaaacct attatgtaag ctggtaccag cagaagccag gccaggtccc tgtactggtc
      241 atctatggta acaccaatag gccctcaggg atcccaggcc gattctctgg ctcatggtca
      301 ggaaactcag gttccttgac catcactggg gctcaggtgg aagatgaggc tgactattac
      361 tgtggctcct gggataacag tgataagcgt tacatcttcg gtgatgggac ccggttcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004548             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:5136:6293
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004548
VERSION     KCWK01004548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5136:6293"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70286.1"
                     /translation="DYYCQVWDSSTKYVLF"
     J_segment       392..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           92 a          141 c          136 g           98 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgc ggcctcctat gaactgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taaaagtgtg cagtggtacc agcagacgcc accgcaggcc cctatactgg
      241 tcatttatgg tgatagggaa cggccctcag ggatccctga tcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggatagt agtactaaat atgtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004549             329 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:7360:16411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004549
VERSION     KCWK01004549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 329)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:7360:16411"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..291
                     /note="immunoglobulin light chain variable region"
     V_region        84..291
     V_segment       84..253
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70287.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       259..291
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>329
                     /gene="IGLC"
BASE COUNT           56 a          105 c           99 g           69 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg cccctgtgct ggtcatctat gctgatagcg
      121 aacggccctc agggatccct gagcgattct ctggctccaa atcagggaac acggccaccc
      181 tgaccatcag cggggtcgag gccgggggtg aggctgacta ttactgtcag gtgtgggaca
      241 tgcgtagtga tcaaccgcta ttcggcggag ggacccggct aaccgtccta ggtcagccca
      301 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004550             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:17785:14858
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004550
VERSION     KCWK01004550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:17785:14858"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70288.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       408..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           90 a          161 c          121 g          108 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcgtcaat
      181 gtgggtagtt acagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
      241 ctgtactacc agtcagactc aaggaagcac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc caatgcaggg ctgttactga tctctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccctatgg cacagcagcg cttcttgcat cttcggtggt
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004551             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:16584:4698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004551
VERSION     KCWK01004551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16584:4698"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70289.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          158 c          122 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004552             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:15550:8589
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004552
VERSION     KCWK01004552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15550:8589"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70290.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       391..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           90 a          144 c          134 g           95 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tcctggtcat
      241 ctatgctaat aacgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg ggcgttacta gtgatcatcc cttattcgga ggagggaccc ggctgaccgt
      421 ccaaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004553             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:14968:8530
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004553
VERSION     KCWK01004553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14968:8530"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70291.1"
                     /translation="DYYCQSVDSSAHHPFF"
     J_segment       398..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          100 a          136 c          124 g          106 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg aggtgacaca
      121 gtcaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagcaat
      181 actggcaaat aattatgctc agtggttcca gcagaagcca gaccaggccc ctgtgttggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gttgacagta gtgcccatca tccgtttttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004554             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:12779:14394
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004554
VERSION     KCWK01004554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12779:14394"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70292.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       408..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          156 c          116 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatatac tggtaccacc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacacat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tgattatatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004555             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18510:13800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004555
VERSION     KCWK01004555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18510:13800"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..260
                     /note="immunoglobulin light chain variable region"
     V_region        4..260
     V_segment       4..224
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>232
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70293.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       228..260
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>298
                     /gene="IGLC"
BASE COUNT           66 a           84 c           88 g           60 t
ORIGIN      
        1 acatggggga gacaacattg gaattaaaac tgtgcactgg taccagcaga agccaccgca
       61 gggccctgta ttggtcatct ttgctgatag taaacggccc tcggggatcc ctgagcgatt
      121 ctctggctcc aactcaggga acaccgccac cctgaccatc agcagggtcg aggccgggga
      181 tgaggctgac tattactgtc aggtgtggga cagtagtagt aaatggatat tcggcggggg
      241 gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004556             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:18492:21328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004556
VERSION     KCWK01004556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18492:21328"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70294.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctatggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg attcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttgttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004557             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:10785:4415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004557
VERSION     KCWK01004557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10785:4415"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70295.1"
                     /translation="DYYCYSYRTGNSWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           84 a          157 c          126 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac caacagcact cagggacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tattgttact catataggac tggaaacagt tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004558             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10440:14426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004558
VERSION     KCWK01004558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10440:14426"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70296.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          151 c          116 g          107 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcccggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004559             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:7902:9796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004559
VERSION     KCWK01004559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:7902:9796"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70297.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          140 c          136 g           98 t
ORIGIN      
        1 catggggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 agcctcggtg tcagtgtccc cgggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaaa aatgtgcact ggtaccagca ggagccaccg caggcccctg tgttggtcat
      241 cttttatgat aacaaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacatcgcc accctgacca tcagcgaggc cgaggccggg gatgaggctg actattactg
      361 tcagctgtgg gacagtagtg ttgatcatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004560             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:4630:17848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004560
VERSION     KCWK01004560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:4630:17848"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70298.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       404..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           86 a          157 c          126 g          109 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggcggtt ataactatgt ctcctggtac caacaacatc cagacacagc
      241 ccccaaactc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca tggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgctgct cacatgcagg cagtgatatt ttcgtgttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004561             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:25691:13442
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004561
VERSION     KCWK01004561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:25691:13442"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70299.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           90 a          157 c          125 g          109 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cggcatggga tgatagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01004562             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:21932:15316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004562
VERSION     KCWK01004562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21932:15316"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..406
                     /note="immunoglobulin light chain variable region"
     V_region        78..406
     V_segment       78..372
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70300.1"
                     /translation="DYYCCSRSSSSTYVF"
     J_segment       373..406
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>446
                     /gene="IGLC"
BASE COUNT           77 a          154 c          107 g          108 t
ORIGIN      
        1 acatggggga cgtctccacc atggcctgga ctctgctcct cgtcaccctc ctcactcaag
       61 gcacaggatc ctgggctcag tctgccccga ctcagcctcc ctctgtgtct gggtctcctg
      121 gacagtcggt caccatctcc tgcactggaa ccagcagtga cgttggtggt tataactctg
      181 tctcctggta ccaacaacac ccaggcaaag cccccaaagt catgattttt ggtgtcaata
      241 atcggccctc tggggtctct gaccgcttct ctggctccaa gtctggcaac acggcctccc
      301 tgaccatctc tgggctccag tctgaggacg aggctgatta ttactgttgt tcacgttcaa
      361 gcagcagcac ttacgtcttc ggtcctggga cccggctcac cgtcctgggt cagcccaagg
      421 cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004563             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:16068:10945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004563
VERSION     KCWK01004563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16068:10945"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70301.1"
                     /translation="DYYCQVWDTTLDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          148 c          130 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gttctggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact cttgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004564             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:7044:16981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004564
VERSION     KCWK01004564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:7044:16981"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70302.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          162 c          116 g          109 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctctgcat ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctgcct accacataca ctggtaccag cagaagccag ggagtcctcc ccggtatctt
      241 ctgagatata aatcagactc agataacgac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcctcagc gaacacggga cttttgcgca tctctgggct ccagtctgag
      361 gatgaggctg actactactg tgccattgga cacagcagcg gtgattacat cttcggtgct
      421 gggacccgcc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004565             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:14043:9612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004565
VERSION     KCWK01004565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14043:9612"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    67..388
                     /note="immunoglobulin light chain variable region"
     V_region        67..388
     V_segment       67..351
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <313..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70303.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       354..388
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           83 a          136 c          111 g           96 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgta
       61 ctcaccctga ctcagccacc ctcagcgtct ggggctcccg ggcagagtgt caccatctct
      121 tgttctggaa gcatctccag cattggaagt agtgatgtat gttggtacca gcaactccca
      181 ggaacggccc ccaaactcct catcaattat agtgatcagc gactctcagg ggtccctgac
      241 cgattctctg gctctaagtc tggcacctca gcctccctgg ccatcactgg tctccgatct
      301 gaggatgagg ctgattatta ctgtgcagcc tgggatagca gcctgagcag tccggtattc
      361 ggcggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      421 ttcccg
//
LOCUS       KCWK01004566             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:24559:5964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004566
VERSION     KCWK01004566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24559:5964"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70304.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       413..448
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           92 a          161 c          125 g          108 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctcgt ctcctctcct cctcaccctt ttcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cacagccgcc ctcagtgtct ggggccccag ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggaggt tattatatat cctggtacca gcagctccca
      241 ggaacggccc ccaaactcct cgtctatgac aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggttcctca gccaccctga ccatcactgg gctccagact
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtctgagtgc tcgggtattc
      421 ggcggaggga cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004567             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:11169:2803
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004567
VERSION     KCWK01004567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:11169:2803"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..444
                     /note="immunoglobulin light chain variable region"
     V_region        96..444
     V_segment       96..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70305.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       410..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          162 c          120 g          109 t
ORIGIN      
        1 acatgggggc tgtggcctca gaggtagccg tgtccaccat ggccctgact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcccagcc tgtgctgact cagccaccct
      121 ccctgtctgc atccccggga gcatcggcca gactcccctg caccctgagc agtgacctca
      181 gtgttggtag taaaaacatg tactggtacc aacagaagcc agggagcgct cccaggttat
      241 tcctgtacta ctactccgac tcagacaagc agctgggacc tggggtcccc aatcgagtct
      301 ctggctccaa ggagacctca agtaacacag cgtttttgct catctctggg ctccagcctg
      361 aggacgaggc cgattattac tgtcaggtgt atgacagtag tgctaatgtc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004568             389 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:19008:19307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004568
VERSION     KCWK01004568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 389)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 389)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..389
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19008:19307"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..351
                     /note="immunoglobulin light chain variable region"
     V_region        80..351
     V_segment       80..314
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <276..>323
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70306.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       315..351
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        352..>389
                     /gene="IGLC"
BASE COUNT           80 a          119 c           97 g           93 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctgcactg ggagcagctc caacattgga gattattttg
      121 tgcagtggta ccagcacctt ccaggaacgg cccccaaact cctcatctat gaaaataata
      181 agcgaccctc agggatttct gatcgattct ctggctccca gtctggaacc tcagcctccc
      241 tgaccatcac tggactccag tctgaggatg aggctgatta ttactgccag tcctatgaca
      301 gcagtttgat tgctgtgtta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      361 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004569             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:3217:14413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004569
VERSION     KCWK01004569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:3217:14413"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70307.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          161 c          110 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcaggacttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004570             451 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:12928:12897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004570
VERSION     KCWK01004570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 451)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12928:12897"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..413
                     /note="immunoglobulin light chain variable region"
     V_region        83..413
     V_segment       83..378
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70308.1"
                     /translation="DYYCSSYAGSNSLVF"
     J_segment       379..413
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>451
                     /gene="IGLC"
BASE COUNT           85 a          148 c          113 g          105 t
ORIGIN      
        1 acatgggtct cgggacatct ccaccatggc ctgggatctg ctcctcttca ccctcctcac
       61 tcagggcaca ggatcctggg ctcaggctgc cctgactcag cctccctcaa tgtctgggtc
      121 tcctggacag tcggtcacca tctcctgcac tggaaacagc actgacattg gtggttctaa
      181 ccgtgtctcc tggtatcaac atcactcaga caaagccccc aaagtcatga tttatgaggg
      241 cagtcagcgg ccctcagggg tctctgatcg cttctctggc tccaagtctg gcaacacggc
      301 ctccctgacc atctctgggc tccaggctga ggatgaggct gattattact gcagctcata
      361 tgcaggcagc aatagtttgg tattcggcgg agggacccgg ctaaccgtcc taggtcagcc
      421 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004571             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:23391:15489
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004571
VERSION     KCWK01004571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23391:15489"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70309.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       411..447
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           96 a          159 c          121 g          109 t
ORIGIN      
        1 acatgggggc gcagcttcag ctgtgggtac agaaggcagg actcaggaca atctccagca
       61 tggcctggtt ccctctcgtc ctcaccctcc tcactcactg tgcagggtcc tgggcccagt
      121 ctgtgctgac tcagcctccc tcagcgtctg aggccgccag gaagagtgtc accatctcct
      181 gttctggaag cacctccaac atcggaagca ataatgtatc ctggtaccag cagctcccag
      241 gaacagctcc caaactcctc ttttattata atgatcaacg agcctcaggt gtctctgacc
      301 gattctcttg ctccaagtct ggcacgtcag cctccctggc catcagtggg ctccagaccg
      361 aggatgaggc tgattattac tgcgcagcat gggatgataa cctgagcggc tacatcttcg
      421 gtgctgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt
      481 tcccg
//
LOCUS       KCWK01004572             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:18820:17551
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004572
VERSION     KCWK01004572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:18820:17551"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..242
                     /note="immunoglobulin light chain variable region"
     V_region        10..242
     V_segment       10..201
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <167..>214
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70310.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       205..242
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        243..>280
                     /gene="IGLC"
BASE COUNT           56 a           89 c           70 g           65 t
ORIGIN      
        1 acatgggaat gtgtcctggt accagcacct cccaggaaca gctcccaaac tcctcatcta
       61 ttataatgat caacgaggct caggtgtctc tgaccgattc tctggctcca agtctggcac
      121 gtcagcctcc ctggccatca gtgggctcca gaccgaggat gaggctgatt attactgcgc
      181 agcgtgggat gatagcctga gtagttacat cttcgctgct gggacccggc tcaccgtcct
      241 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004573             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:16539:19702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004573
VERSION     KCWK01004573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16539:19702"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70311.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           92 a          159 c          112 g          110 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt ggtgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004574             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:2552:10391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004574
VERSION     KCWK01004574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:2552:10391"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70312.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           91 a          142 c          132 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gtctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtgctggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccgactg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004575             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:14273:18209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004575
VERSION     KCWK01004575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14273:18209"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..446
                     /note="immunoglobulin light chain variable region"
     V_region        98..446
     V_segment       98..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70313.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           94 a          161 c          122 g          107 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga cgcagccacc
      121 ctccctgtct gcatccccgg gagcaccggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggc agtaaaaaca tgtactggta ccaacagaag ccagggagcg ctcccaggtt
      241 atttctgtac tacaactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg atcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt atatgacagt agtgctaatg tgttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01004576             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10555:16573
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004576
VERSION     KCWK01004576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10555:16573"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70314.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          142 c          132 g           94 t
ORIGIN      
        1 acatggggtg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgaa ctgactcagt
      121 caccctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca
      181 ttggaattaa aactgtacac tggtaccagc agaagccacc gcagggccct gtattggtca
      241 tctttgctga tagtaagcgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004577             338 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18474:12792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004577
VERSION     KCWK01004577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 338)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18474:12792"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..300
                     /note="immunoglobulin light chain variable region"
     V_region        8..300
     V_segment       8..263
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <228..>272
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70315.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       264..300
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        301..>338
                     /gene="IGLC"
BASE COUNT           71 a          105 c           81 g           81 t
ORIGIN      
        1 acatgggcag actcagctgc accttgagca gtggcaatgt tggtagttac agcatattct
       61 ggtaccagca gaagccaggg agtcctcccc ggtaccttct ttactactac tcagactcaa
      121 gtaaccacca ggactctgga gtccccagcc gcttctctgg atcgaaagat gcttcagcca
      181 atgcagggct tttactgatc tctgggctcc agtctgaaga tgaggctgac tattactgtg
      241 ccacatggca cagcagcgct tcttacatct tcggtcctgg gacccggctc accgtcctag
      301 gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01004578             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:6841:22282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004578
VERSION     KCWK01004578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6841:22282"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70316.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           92 a          147 c          129 g           96 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gtactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttattcgg agaagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004579             282 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:24196:15830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004579
VERSION     KCWK01004579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 282)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24196:15830"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..244
                     /note="immunoglobulin light chain variable region"
     V_region        8..244
     V_segment       8..208
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <175..>216
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70317.1"
                     /translation="DYYCALWYNSAWIF"
     J_segment       209..244
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        245..>282
                     /gene="IGLC"
BASE COUNT           59 a           87 c           73 g           63 t
ORIGIN      
        1 acatgggggt accaacagaa gccagggcgt cctccccggt accttctgaa ctactactca
       61 gactcaaata agggccaggg ctctggagtc cccagccgct tctctggatc caaagatgct
      121 tcagccaatg caggactttt actgatctct gggctccagt ctgaggatga ggctgactat
      181 tactgtgcct tatggtacaa cagcgcttgg atattcggcg gagggacccg gctaaccgtc
      241 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004580             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:22196:10498
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004580
VERSION     KCWK01004580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22196:10498"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70318.1"
                     /translation="DYYCAVWDNSLTSPLF"
     J_segment       401..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           92 a          153 c          117 g          107 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gataatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 accctcagcg tctgggactc ccgggcagag tgtcaccatc tcttgctctg gaagcaactc
      181 caacattgga aataattatg tatactggta ccagcacctc ccaggaacgg cccccaagct
      241 cctcatctat tatagttatc agcgaccctc aggggtccct gaccgattct ctggctctaa
      301 gtctggcacc tcagcctccc tggccatcac tggtctccga actgaggatg aggctgatta
      361 ttactgtgca gtatgggata acagcctgac cagtccgttg ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004581             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:22068:12076
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004581
VERSION     KCWK01004581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22068:12076"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..400
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70319.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       409..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           93 a          155 c          122 g          107 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc ggacagaggg tcaccatctc ctgcattagc
      181 agcagctcca acatcggggc ggcttattat gtatcctggt accaacagtt cccaggaaca
      241 gcccccaaac tcctcatcta tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggtcc ctcagcctcc ctgaccatca ctggactcca atctgaggat
      361 gaggctgatt attactgttt agcatgggat accagcctga attggatctt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004582             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:28273:19168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004582
VERSION     KCWK01004582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:28273:19168"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70320.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          158 c          127 g          111 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaccgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagtc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004583             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11892:15591
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004583
VERSION     KCWK01004583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11892:15591"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70321.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          144 c          131 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004584             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:8519:11175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004584
VERSION     KCWK01004584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:8519:11175"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70322.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          148 c          130 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtaca ctggtaccag cacgagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttgttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004585             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20930:7656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004585
VERSION     KCWK01004585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20930:7656"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70323.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       393..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          153 c          121 g          107 t
ORIGIN      
        1 acatgggggt acagaaggca ggactcagga caatctccag catggcctgg ttccctctcg
       61 tcctcaccct cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagcctc
      121 cctcagcgtc tgaggccgcc aggaagagtg tctccatctc ctgttctgga agcagctcca
      181 acatcggaag tcatagtgtc tcctggtacc agcagctccc aggaacagct cccaaactcc
      241 tcatctatta tagtgatcaa cgagcctcag gtgtctctga ccgattctct ggctctcagt
      301 ctggcacgtc agcctccctg gccatcagtg ggctccaggc cgaggatgag gctgattatt
      361 actgcgcagc atgggatgat agtctgagcg gttacatctt cggtgctggg acccggctcg
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01004586             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:8509:18189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004586
VERSION     KCWK01004586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8509:18189"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70324.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          147 c          130 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004587             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18265:17298
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004587
VERSION     KCWK01004587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18265:17298"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    62..410
                     /note="immunoglobulin light chain variable region"
     V_region        62..410
     V_segment       62..373
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <338..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70325.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       374..410
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>448
                     /gene="IGLC"
BASE COUNT           86 a          151 c          110 g          101 t
ORIGIN      
        1 acatggggcc ctgactcctc tcctcctcct gctcctctct cactgcacag gttccctctc
       61 ccagcctgtg ctgactcagc caccctccct gtctgcatcc ccgggagcat cggccagact
      121 cccctgcacc ctgagcagtg acctcagtgt tggtagtaaa aacatgtact ggtaccagca
      181 gaagccaggg agcgctccca ggtcatttct gtactactac tccgactcag acaagcagct
      241 gggacctggg gtccccaatc gagtctctgg ctccaaggag acctcaagta acacagcgtt
      301 tttgctcatc tctggactcc agcctgagga cgaggccgat tattactgtc aggtgtatga
      361 cagtagtgcg aatgtgttat tcggaggagg gacccggctg accgtcctag gtcagcccaa
      421 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004588             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:14377:4675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004588
VERSION     KCWK01004588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14377:4675"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70326.1"
                     /translation="DYYCAAWDDGLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          157 c          121 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc aacgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca actccaacat cggaaattat aatgtgtcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatggcc tgagcggtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004589             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:12184:11897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004589
VERSION     KCWK01004589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12184:11897"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..423
                     /note="immunoglobulin light chain variable region"
     V_region        93..423
     V_segment       93..384
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70327.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       386..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           87 a          144 c          120 g          110 t
ORIGIN      
        1 acatggggga ggcagcactc aggacagtct ccagcatggc ctggtctcct ctcctcctca
       61 cccttctcat tcactgcaca gggtcctggg cccagtctgt gctgacgcag ccgccctcag
      121 tgtctggggc gcccgggcag agggtcagta tttcttgcac tgggagcagc tccaacattg
      181 gaggttatta tgtgcagtgg taccagcagc ttccaggaac ggcccccaaa ctcctcatct
      241 atgaaaatga taaacgaccc tcagggattt ctgatcgatt ctctggctcc cagtctgatt
      301 cctcagcctc cctgaccatc actggactcc agtctgagga tgaggctgat tattactgcc
      361 agtcctatga cagcagcttg agtgttgtgt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004590             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:6926:8341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004590
VERSION     KCWK01004590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:6926:8341"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70328.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           89 a          142 c          139 g           91 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgcggggga gacaagattg
      181 gaagtgaagt tgtgaactgg taccagaaga agccagcgca ggcccctgca ctggtcatct
      241 atgctgatag cgaacggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acacggccac cctgaccatc aggggggtcg aggccggggg tgaggctgac tattactgtc
      361 aggtgtggga catgcgtagt gatcaaccgc tattcggcgg agggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004591             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:18177:21705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004591
VERSION     KCWK01004591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18177:21705"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    19..349
                     /note="immunoglobulin light chain variable region"
     V_region        19..349
     V_segment       19..310
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <274..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70329.1"
                     /translation="DYYCSAWDSSLTGGFF"
     J_segment       312..349
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>387
                     /gene="IGLC"
BASE COUNT           77 a          122 c          102 g           86 t
ORIGIN      
        1 acatggggat cctgggccca gtctgtgctg actcaaccac cctcagcgtc tggggccccc
       61 gggcagagtg tcaccatctc ctgttctgga agcagctcca acatcggaag taattatgta
      121 tactggtacc agcagttctc agggaaggcc cccaaactcc tcatccataa taataatcag
      181 cgaccctcag gggtccctga tcgattctct ggctccaagt ctggcacgtc agcctccctg
      241 gacatcagtg ggctccagtc cgaggatgag gctgattatt actgctcagc atgggatagc
      301 agtctgaccg gtggcttttt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      361 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004592             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10190:18035
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004592
VERSION     KCWK01004592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10190:18035"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..388
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70330.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       389..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           89 a          141 c          128 g          100 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagagctct ggggtgtctc caccatggcc tggactcctc
       61 tctggctcac cctcctcagt ctttgcacag gttctatggt ttcttctgag ctgactcagg
      121 accctgcagt gtctgtggcc ttgggacaga cagtcaggat tacctgccaa ggagacagcc
      181 tcagaagctc ttatgcaagc tggtaccaac agaggccggg ccaggcccct gtgctggtcg
      241 tctatggtaa caactaccgg ccctcaggga tcccagagcg attctctggc tcctactcac
      301 gaaacacagc ttccttgacc atctctgggg ctcaggtgga agatgaggct gactattact
      361 gtgactcctg ggacagcagc ggaacccaat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004593             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:6644:13094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004593
VERSION     KCWK01004593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:6644:13094"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..397
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70331.1"
                     /translation="VYYCAIGHSSGDYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           91 a          155 c          120 g          109 t
ORIGIN      
        1 acatgggggg gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccaa gcctatgctg actcagccgg cctccctctc
      121 agcatctcct ggagcatcag ccagtctcac atgcaccttc agcggtggca tcaatgttgc
      181 tggctaccac atacactggt accagcagaa gtcagggagt cctccccggt atcttctaag
      241 atacaaatca gactcagatc agggccaggg ctctggagtc cccagccgct tctctggatc
      301 caaagatgct tcagcgaaca cggggatttt acacgtctct gggctccagt ctgaggatga
      361 ggctgtctat tactgtgcca ttgggcacag cagcggtgat tacatcttcg gtggtgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004594             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12768:10926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004594
VERSION     KCWK01004594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12768:10926"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70332.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       387..424
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           89 a          138 c          140 g           95 t
ORIGIN      
        1 acatggggga ctttgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctttacaggc tctgcggcct cctatgaggt gactcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtaaaa gtgtgcagtg gtaccagcag acgccaccgc aggcccctgt actggtcatt
      241 tatggtgata gggaacggcc ctcagggatc cctgagcgat tctctggctc caactcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg atagcagtag taaatatgtg ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004595             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:19715:18127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004595
VERSION     KCWK01004595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19715:18127"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70333.1"
                     /translation="YYYCSSYAGSHTYIF"
     J_segment       400..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           78 a          164 c          121 g          110 t
ORIGIN      
        1 acatgggggg gggtctcagg gggcagcgct ctcaggacgt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca cagggtcctg ggctcaggct gccctgactc
      121 agcctccctc tgtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggttat aactatgtct cctggttcca gcagcacccc ggcaaagccc
      241 ccaaactcat gatttatgat gtcactcagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaaatc tggctacacg gcctccctga ccatctctgg gctccaggct gcggatgagg
      361 cttattatta ctgcagctca tatgcgggca gccacactta catcttcggt actgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004596             282 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:20614:17745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004596
VERSION     KCWK01004596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 282)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:20614:17745"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..244
                     /note="immunoglobulin light chain variable region"
     V_region        8..244
     V_segment       8..207
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <169..>216
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70334.1"
                     /translation="DYYCAAWDDSLRGYLF"
     J_segment       208..244
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        245..>282
                     /gene="IGLC"
BASE COUNT           56 a           88 c           73 g           65 t
ORIGIN      
        1 acatgggata gtgtatcctg gtaccagcag ctcccaggaa cagctcccaa actcctcatc
       61 tattatgatg atcaacgagc ctcaggtgtc tctgaccgat tctctggctc caggtctggc
      121 acgtcagcct ccctggccat cagtgggctc cagaccgagg atgaggctga ttattactgc
      181 gcagcatggg atgatagcct gagaggttac ctcttcggtg atgggacccg gctcaccgtc
      241 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01004597             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:13381:20119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004597
VERSION     KCWK01004597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13381:20119"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70335.1"
                     /translation="DYYCQMYDNSDVLF"
     J_segment       410..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           94 a          161 c          119 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcaga tgtatgacaa tagtgatgtc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004598             384 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:19044:3026
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004598
VERSION     KCWK01004598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 384)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 384)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:19044:3026"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    16..346
                     /note="immunoglobulin light chain variable region"
     V_region        16..346
     V_segment       16..302
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <274..>318
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70336.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       316..346
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        347..>384
                     /gene="IGLC"
BASE COUNT           77 a          121 c           96 g           90 t
ORIGIN      
        1 acatgggcct gggctcaggc tgccccgact cagactccct ctgtgtccgg gtctcctgga
       61 cagtcggtca ccatctcctg cactggaacc agcagtgata ttgggtatta tcatgctgtg
      121 tcttggtacc aacatcatcc aggcaaagcc cccaaactca taatttatga ggtcaataaa
      181 cggcccgcag gggtctctga tcgcttctct ggctccaagt ctggcaagac ggcctccctg
      241 accatctctg gactccagac tgaggatgag gctgattatt actgcagctc atatgcaggc
      301 agcaacgctt tattcttcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct
      361 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004599             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:12580:19919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004599
VERSION     KCWK01004599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12580:19919"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70337.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       387..424
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           89 a          137 c          140 g           96 t
ORIGIN      
        1 acatggggga ctttgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctttacaggc tctgcggcct cctatgaggt gactcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtaaaa gtgtgcagtg gtaccagcag acgccaccgc aggcccctgt actggtcatt
      241 tatggtgata gggaacggcc ctcagggatc cctgagcgat tctctggctc caactcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg atagtagtag taaatatgtg ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004600             410 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:9963:5686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004600
VERSION     KCWK01004600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 410)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9963:5686"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    42..372
                     /note="immunoglobulin light chain variable region"
     V_region        42..372
     V_segment       42..328
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <300..>344
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70338.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       342..372
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        373..>410
                     /gene="IGLC"
BASE COUNT           81 a          131 c          103 g           95 t
ORIGIN      
        1 acatgggcac cctcctcact cagggcacag gatcctgggc tcaggctgcc ccgactcaga
       61 ctccctctgt gtccgggtct cctggacagt cggtcaccat ctcctgcact ggaaccagca
      121 gtgatattgg gtattatcat gctgtgtctt ggtaccagca tcatccaggc aaagccccca
      181 aactcatgat ttatgaggtc aataaacggc ccgcaggggt ctctgatcgc ttctctggct
      241 ccaagtctgg caacacggcc tccctgacca tctctgggct ccagactgag gatgaggctg
      301 attattactg tagctcatat gcaggcagca acagtttatt cttcggagga gggacccggc
      361 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004601             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:23056:13983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004601
VERSION     KCWK01004601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23056:13983"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70339.1"
                     /translation="DYYCQVWDTSIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          146 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgagg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggccccta tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004602             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:21066:6707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004602
VERSION     KCWK01004602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21066:6707"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..434
                     /note="immunoglobulin light chain variable region"
     V_region        115..434
     V_segment       115..409
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70340.1"
                     /translation="DYYCQSFDSSGFWVF"
     J_segment       411..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>486
                     /gene="IGLC"
BASE COUNT           85 a          161 c          128 g          112 t
ORIGIN      
        1 acatgggggc tcattcctgg ctgtggctca ggaagcagag cctggagcat ctccaccatg
       61 gcctgggctc cactcctcct caccctcctc gctcactgca cagggtcttg ggctgaggtt
      121 gtgttcattc agccccattc tgtgtcgggg tctccggggc agacggtcac catctcctgc
      181 acccgcagca gtggcagcat tgacaacagc tatgtgtact ggtaccagca gcggccgggc
      241 agcgccccca ccactctgat ttacaaagat aaccaaagac cctctggggt ccctgatcgg
      301 ttctctggct ccatcgacag ctcctccaac tctgcctccc tcaccatctc tggactgaag
      361 tctgaggacg aggcagacta ttactgtcag tcttttgaca gcagcggttt ttgggtgttc
      421 ggcggaggga cccgactaag tgtccttggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004603             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:24381:19004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004603
VERSION     KCWK01004603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24381:19004"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..439
                     /note="immunoglobulin light chain variable region"
     V_region        94..439
     V_segment       94..403
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70341.1"
                     /translation="DYYCAIWHSSAWVF"
     J_segment       404..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           95 a          158 c          114 g          110 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag tgccatcaat
      181 gttggtagtt acagcatatt ctggtaccag cagaggccag ggagtcctcc ccgatacttt
      241 ttgaactact actcagactc aaataaccac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatacagga cttttactga tctctgggct ccagtctgaa
      361 gatgaggctg actattattg tgccatatgg cacagcagcg cttgggtctt cggcggaggg
      421 acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004604             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:24699:18217
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004604
VERSION     KCWK01004604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:24699:18217"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70342.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       406..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           88 a          158 c          129 g          103 t
ORIGIN      
        1 acatggggct ggctgtggct caggaagcag agcctggagc gtctccacca tggcctgggc
       61 tccactcctc ctcaccctcc tcgctcactg cacagggtct tgggctgagg ttctgttcac
      121 gcagccccat tctgtgtcgg ggtctccggg gcagacggtc accatctcct gtacccgcag
      181 cagaggcaac attgacaata gttatgtgca gtggtaccag cagcgcccgg gcagtgcccc
      241 gaccacagtg atttacagag ataaccaaag agcctctggg gtccctgatc ggttctctgg
      301 ctccatcgac agctcctcca actctgcctc cctcaccatc tctgggctga agtctgagga
      361 cgaggctgac tactactgtc agtctactga tggcaactac aatcggttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004605             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:9294:2451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004605
VERSION     KCWK01004605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9294:2451"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70343.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          156 c          127 g          106 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agactccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctgggagca gctccaacat cggaagaaat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagcgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004606             345 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:17588:11716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004606
VERSION     KCWK01004606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 345)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17588:11716"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..307
                     /note="immunoglobulin light chain variable region"
     V_region        8..307
     V_segment       8..268
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <235..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70344.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       270..307
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>345
                     /gene="IGLC"
BASE COUNT           76 a           99 c           85 g           85 t
ORIGIN      
        1 acatgggcag ccagactcac ctgcaccttg aacagtggca tcagtgttgg taattacagg
       61 atattctggt accaccagaa gccagggagt cctccccggt atcttctgaa ctaccacaca
      121 gactcagata ttcatcaggg gtctggagtc cccagccgct tctctggatc caaagatgct
      181 tcggccaatg cagggatttt actcatctct ggactccagt ctgaggatga ggctgactat
      241 tactgtatga tttggcacaa caatgcttat tgggttttcg gcggagggac ccggctaacc
      301 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004607             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:11764:4019
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004607
VERSION     KCWK01004607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11764:4019"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..409
                     /note="immunoglobulin light chain variable region"
     V_region        79..409
     V_segment       79..370
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70345.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       372..409
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           82 a          143 c          117 g          105 t
ORIGIN      
        1 acatggggga ggacagtctc cagcatggcc tggtctctcc ttctcactct gctgcttcac
       61 tgcacagggt cctgggccca gtctgtgctg acgcagccgc cctcagcatc tggggccccc
      121 gggcagaggg tcaccatctc ctgctctggg agcagctcca acatcggggc gggtttttat
      181 gtatcctggt accagcagtt cccaggaaca gcccccaaac tcctcatctt tgaaaataat
      241 aagcgaccct caggggtttc tgaccgattc tctggctcca agtctggttc ctcagcctcc
      301 ctgaccatca ctggactcca atctgaggat gaggctgatt attattgttc atcatgggaa
      361 agcagcctga attgggtatt cggcggaggg acccggctga ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004608             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:21794:13822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004608
VERSION     KCWK01004608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:21794:13822"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70346.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       386..421
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           97 a          143 c          120 g           99 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactcccca tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agaagaattg
      181 ccaaaaaaat atgcttattg gttccagcag aagccaggcc agtcccctgt ccagatcatc
      241 tatgaggaca gtaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cactggggcc caggtggagg atgaagctga ctactactgt
      361 ttctcaacag acaccagtgg taatcgggta ttcggcggag ggacccgtct aaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004609             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:12905:13436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004609
VERSION     KCWK01004609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:12905:13436"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..436
                     /note="immunoglobulin light chain variable region"
     V_region        107..436
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70347.1"
                     /translation="DYYCSSFAGRNNLFF"
     J_segment       407..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>475
                     /gene="IGLC"
BASE COUNT           87 a          156 c          119 g          113 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtaat cttgggtatt ttaatgctgt gtcttggtac caacaacatc caggcaaagc
      241 ccccaaactc atgatttacg acgtcactaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgcagtt catttgccgg caggaacaat ttatttttcg gaggagggac
      421 ccggctgacc gtcctaagtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004610             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:7622:20514
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004610
VERSION     KCWK01004610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7622:20514"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..421
                     /note="immunoglobulin light chain variable region"
     V_region        103..421
     V_segment       103..389
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70348.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       390..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           91 a          141 c          127 g          100 t
ORIGIN      
        1 acatggggtg tgggctcaga agcagagctc tggggtgtct ccaccatggc ctggactcct
       61 ctctggctca ccctcctcag tctttgcaca ggttctatgg tttcttctga gctgactcag
      121 gaccctgcag tgtctgtggc cttgggacag acagtcagga ttacctgcca aggagacagc
      181 ctcagaagct cttatgcaag ctggtaccaa cagaggccag gccaggcccc tgtgctggtc
      241 gtctatggta acaactaccg gccctcaggg atcccagagc gattctctgg ctcctactca
      301 cgaaacacag cttccttgac catcactggg gctcaggtgg aagatgaggc tgactattac
      361 tgtgactcct gggacagcag cggaacccaa ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004611             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:8575:4341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004611
VERSION     KCWK01004611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8575:4341"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70349.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           97 a          142 c          121 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaagaatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tccagatcat
      241 ctatgaggac agtaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 tttctcaaca gacaccagtg gtaatcgggt attcggtgga gggacccgtc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004612             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:14031:8211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004612
VERSION     KCWK01004612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14031:8211"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70350.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          140 c          139 g           98 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactttac aggctctgcg gcctcctatg aggtgactca
      121 gccacgctca gtgtccgtgt cccccggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt aaaagtgtgc agtggtacca gcagacgcca ccgcaggccc ctgtactggt
      241 catttatggt gatagggaac ggccctcagg gatccctgag cgattctctg gctccaactc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggatagta gtagtaaata tgtattattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagt ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004613             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:21040:10418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004613
VERSION     KCWK01004613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21040:10418"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70351.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           91 a          141 c          133 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtt cccaggacag acggccaggg tcacctgtgg aggagacagc
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtgctggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgaac gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtattat tcggaggagg gacccgactg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004614             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:7888:4639
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004614
VERSION     KCWK01004614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:7888:4639"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70352.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          156 c          127 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cacctccaac attggaggtt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctatgaaa atgataaacg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct gattcctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cttgagtgtt gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004615             391 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:9927:9853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004615
VERSION     KCWK01004615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 391)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9927:9853"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..353
                     /note="immunoglobulin light chain variable region"
     V_region        8..353
     V_segment       8..316
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>325
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70353.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       317..353
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        354..>391
                     /gene="IGLC"
BASE COUNT           80 a          123 c          101 g           87 t
ORIGIN      
        1 acatgggcag cctgtgctga ttcagccacc ctccctgtct gcatccccgg gagcatcggc
       61 cagactcccc tgcaccctga gcagtgacct cagtgttggt aataaaaaca tgtactggta
      121 ccaacagaag ccagggagcg ctcccaggtt attcctgtac tactactccg actcagacaa
      181 gcagctggga cctggggtcc ccaatcgagt ctctggctcc aaggagacct caactaacac
      241 agcgtttttg ctcatctctg ggctccagcc tgaggacgag gccgattatt actgtcaggt
      301 gtttgacagt agtgctgtgt tgttcggagg agggacccga ctgaccgtcc taggtcagcc
      361 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004616             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:26048:9837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004616
VERSION     KCWK01004616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:26048:9837"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70354.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       412..448
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          157 c          128 g          110 t
ORIGIN      
        1 acatggggag cgcagcttca gctgtgggta cagaaggcag gactcaggac aatctccagc
       61 atggcctggt tccctctcgt cctcaccctc ctcactcact gtgcagggtc ctgggcccag
      121 tctgtgctga ctcagcctcc ctcagcgtct gaggccgcca ggaagagtgt ctccatctcc
      181 tgttctggaa gcagctccaa catcggaagt catagtgtct cctggtacca gcaagtccca
      241 ggaacagctc ccaaactcct catctattat agtgatcaac gagcctcagg tgtctctgac
      301 cgattctctg gctctcagtc tggcacgtca gcctccctgg ccatcagtgg gctccagacc
      361 gaggatgagg ctgattatta ctgcgcagca tgggatgata gcctgagggg ttacatcttc
      421 ggtgctggga cccggctcgc cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      481 ttcccg
//
LOCUS       KCWK01004617             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:18149:9614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004617
VERSION     KCWK01004617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18149:9614"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70355.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           86 a          165 c          124 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg cctgcgtccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagccc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004618             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:16537:2839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004618
VERSION     KCWK01004618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16537:2839"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70356.1"
                     /translation="DYYCQVWGMTRDHPVF"
     J_segment       389..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           87 a          142 c          140 g           92 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag actctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggagaga cggccaggat cacctgtggg ggagaccaca
      181 ttggaagtga ggttgtgaac tggtaccaac agaagccacc gcaggcccct gtggtggtct
      241 atcctaatag cgaacggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acacggccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtgggg catgactagg gatcatccgg tattcggcgg agggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004619             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:15187:12074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004619
VERSION     KCWK01004619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:15187:12074"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70357.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          138 c          136 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat cccggagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004620             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:13593:18170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004620
VERSION     KCWK01004620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13593:18170"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..397
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70358.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       399..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           88 a          150 c          119 g          113 t
ORIGIN      
        1 acatggggga tctcaggagg cagcgctctc aggacttctc caccatggtc tgggctctgc
       61 tcctcctcac cctcctcact caggacacag gatcctgggt tcaggctgcc ccgactcagc
      121 ctccctctgt gtccgggtct cctggacagt cggtcaccat ctcctgcact ggaaccagca
      181 gtgatgttgg gtattataac gctgtgtctt ggtaccaaca gcatccaggc aaagccccca
      241 aactcatgat ttatgacgtc attaagcggc cctcaggggt ttctgatcgc ttctctggct
      301 ccaagtctgg cgacacggcc tccctgacca tctctgggct ccaggctgag gatgaggctg
      361 attattactg cagctcatat gcaggcagaa ataatttttt attcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004621             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:20981:9222
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004621
VERSION     KCWK01004621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20981:9222"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70359.1"
                     /translation="DYHCQVFDSRDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          159 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcatcctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccagat
      241 tattcctgta ctactattcc gactcagaca aggagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggaaacc tcaagtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtttgacag tcgtgatgtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004622             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:19338:19161
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004622
VERSION     KCWK01004622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19338:19161"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70360.1"
                     /translation="DYYCSSRSSSSTYVF"
     J_segment       399..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           82 a          162 c          116 g          112 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacgtt ggtggttata actctgtctc ctggtaccaa caacacccag gcaaagcccc
      241 caaagtcatg atttttggtg tcaataatcg gccctctggg gtctctgacc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagtctg aggacgaggc
      361 tgattattac tgttcttcac gttcaagcag cagcacttac gtcttcggtc ctgggacccg
      421 gctcaccgtc ctgggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01004623             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:18684:3184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004623
VERSION     KCWK01004623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18684:3184"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70361.1"
                     /translation="DYYCQVYDNSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          165 c          122 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacaa tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004624             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15662:4712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004624
VERSION     KCWK01004624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15662:4712"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70362.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          161 c          115 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 ctgcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcactgttg
      181 ctgcctacca catacactgg taccaacaga agccagggag tcctccccgg tatcttctga
      241 ggttcaaatc agactcagat aaggaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ctcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ctactgtgcc attgggcaca gcagcggtga ttacatcttc ggttctggga
      421 cccgcctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004625             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:14886:17694
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004625
VERSION     KCWK01004625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14886:17694"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70363.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          154 c          120 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcattctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004626             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:21977:12737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004626
VERSION     KCWK01004626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21977:12737"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70364.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          155 c          122 g          104 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtctccatc tcctgttcgg gaagcagctc
      181 caacatcgga agtcatagtg tctcctggta ccagcaactc ccaggaacag ctcccaaact
      241 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctccca
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgcg gcatgggatg atagcctgag cggttacatc ttcggtgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004627             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:10581:10386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004627
VERSION     KCWK01004627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10581:10386"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70365.1"
                     /translation="AYYCQVWDGDSDHYIF"
     J_segment       388..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          148 c          129 g           93 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacaga ctctgcgacc tcctatgagc tgactcagcc
      121 accctcggtg tcaacggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaat tttgtgcact ggtaccagca gaagccagcg caggccccta tgcaggtcat
      241 ctatgctgat aacaaacggc cctcagggat ccctgagaga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggagt cgaggccggg gatgaggctg cctattactg
      361 tcaggtgtgg gacggtgata gtgatcatta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004628             295 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:11652:21594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004628
VERSION     KCWK01004628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 295)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:11652:21594"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..257
                     /note="immunoglobulin light chain variable region"
     V_region        8..257
     V_segment       8..221
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <185..>229
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70366.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       222..257
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>295
                     /gene="IGLC"
BASE COUNT           62 a           92 c           73 g           68 t
ORIGIN      
        1 acatggagac atcggtggtt ataactatgt ctcctggtac caacagcatc caggcacagc
       61 ccccaaagtc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      121 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      181 ggctgattat tactgcagct catatacagg catcaacagt tacatcttcg gtggtgggac
      241 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004629             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:7374:5016
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004629
VERSION     KCWK01004629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7374:5016"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70367.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          120 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctccttct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004630             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:11984:10799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004630
VERSION     KCWK01004630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11984:10799"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70368.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       381..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           90 a          138 c          123 g          101 t
ORIGIN      
        1 acatggggag cattgacggt gcctcagcca tggcctggac ttttctcctc ctcggcctcc
       61 ttgcttactg cacaggctct gcggcctcct atgatctgac tcagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gtggaggaga caacattgga agtgaagttg
      181 tcaactggta ccagcagaag ccaccgcagg cccctgtact ggtcatctat gctgattatg
      241 aacggccctc agggatccct gagcgattct ctggctccaa atcagggaac acggccaccc
      301 tgaccatcag cggagtcgac gccggggatg aggctgacta ttattgtcag gtgtgggaca
      361 tttatattga ccatccggtt ttattcggag gagggacccg actgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004631             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:18740:13864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004631
VERSION     KCWK01004631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18740:13864"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70369.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           96 a          158 c          119 g          109 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcac ctccaacatc ggaagcaata atgtatcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcttt tattataatg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctcttgctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgataacct gagcggctac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01004632             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:15689:8450
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004632
VERSION     KCWK01004632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15689:8450"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..388
                     /note="immunoglobulin light chain variable region"
     V_region        92..388
     V_segment       92..351
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <316..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70370.1"
                     /translation="DYYCAIWHSSASYIF"
     J_segment       352..388
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           83 a          141 c           97 g          105 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagactca gctgcacctt gaacagtggc
      121 atcaatgttg gtagttacag catattctgg taccagcaga agccagggag tcctccccgg
      181 taccttcttt actactactc agactcaact taccaccagg gctctggagt ccccagccgc
      241 ttctctggat ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag
      301 tctgaagatg aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacatcttc
      361 ggtcctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      421 ttcccg
//
LOCUS       KCWK01004633             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:5603:16224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004633
VERSION     KCWK01004633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5603:16224"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..442
                     /note="immunoglobulin light chain variable region"
     V_region        96..442
     V_segment       96..407
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70371.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       410..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>482
                     /gene="IGLC"
BASE COUNT           89 a          167 c          113 g          113 t
ORIGIN      
        1 acatggggcc cactgcaggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcccagcc tgtgctgacc cagccaacct
      121 ccctctcagc atctccggga gcatcagcca gactcagctg caccttgagc agtggcacca
      181 atgttggtag ttacagcatt ttctggtacc agcagaagcc agggagtcct ccccggtacc
      241 ttctctacta ctactcagac tcaactaagc accagggctc tggagtcccc agccgcttct
      301 ctggatccaa agatgattca gccaatgcag ggcttttact gatctctggg ctccagtctg
      361 aggatgaggc tgactattac tgtgccattt ggcacagcag cgcttcttgc atcttcggtc
      421 ctgggacccg gctcaccgtc ctgggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01004634             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:7036:4640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004634
VERSION     KCWK01004634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:7036:4640"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70372.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          162 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaacg cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004635             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:19959:18553
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004635
VERSION     KCWK01004635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19959:18553"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70373.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       414..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          154 c          128 g          114 t
ORIGIN      
        1 acatgggggg ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt cacgatctcc
      181 tgcagtggga gcaactccaa cattggatat tattatgtgc agtggtacca gcagcttcca
      241 ggaacggccc ccaaactcct catctatgaa aataataagc gaccctctgg ggtttctgat
      301 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccactcc tatgacagca gtttgagtgg tgtcttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004636             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:16022:19949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004636
VERSION     KCWK01004636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16022:19949"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..401
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70374.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       402..436
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           89 a          157 c          120 g          108 t
ORIGIN      
        1 acatggggct gggatctcac gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccccgact
      121 cagactccct ctgtggccgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgata ttgggtatta tcatgctgtg tcttggtacc aacatcatcc aggcaaagcc
      241 cccaaactca tgatttatga ggtcaataaa cggcccgcag gggtctctga tcgcttctct
      301 ggctccaagt ccggcaacac ggcctccctg accatctctg ggctccagac tgaggatgag
      361 gctgattatt actgcagctc atatgcaggc agcaacactt tgttcttcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004637             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:24612:10537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004637
VERSION     KCWK01004637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24612:10537"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70375.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>480
                     /gene="IGLC"
BASE COUNT           86 a          163 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggcccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004638             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:9440:19767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004638
VERSION     KCWK01004638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9440:19767"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70376.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       408..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           91 a          161 c          120 g          108 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcaactgca ccttgagcag tggcgtcaat
      181 gtgggtagtt acagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
      241 ctgtactacc agtcagactc aaggaagcac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc caatgcaggg ctgttactga tctctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccctatgg cacagcagcg cttcttgcat cttcggtggt
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004639             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:4795:16553
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004639
VERSION     KCWK01004639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:4795:16553"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    128..449
                     /note="immunoglobulin light chain variable region"
     V_region        128..449
     V_segment       128..413
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70377.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       417..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           98 a          151 c          140 g           98 t
ORIGIN      
        1 acatggggga agcctggaag gcacctgccc tgtctgggtc tcaggaggca gcattgacgg
       61 tgcctcagcc atggcctgga cccttctcct cctcggcctc ctcgcttact gcacaggctc
      121 tgcgacctcc tatgaattga ctcagtcacc ctcagtgtca gcggcctcag gacagccggc
      181 caggatcacc tgtgggggag acaacattgg aactaaaact gtgcactggt accaacagaa
      241 gccaccgcag ggccctgtat tggtcatctt tgctgatagt agacggccct cagggatccc
      301 tgagcgattc tctggctcca actcagggaa caccgccacc ctgaccatca gcagggtcga
      361 ggccggggat gaggctgact attactgtca ggtgtgggac agtagtagta aatggatatt
      421 cggcgggggg acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01004640             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:15020:17295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004640
VERSION     KCWK01004640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15020:17295"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70378.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          152 c          119 g          101 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagactccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagaa atagtgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagcggg ctccaggccg aggatgacgc tgattattac
      361 tgcgcagcat gggatgatag cctgaggggt tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004641             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16347:15626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004641
VERSION     KCWK01004641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16347:15626"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70379.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          106 a          136 c          120 g          101 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tctgtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatactcagt ggttccaaca gcagccaggc caggcccctt tcctggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacaatt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagta gacagcagtg gaaatcttcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004642             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12812:10838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004642
VERSION     KCWK01004642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12812:10838"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..436
                     /note="immunoglobulin light chain variable region"
     V_region        90..436
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70380.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           90 a          162 c          109 g          115 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt tagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atttggcaca gcagcgcttc ttacttcttc ggtactggga
      421 cccgtctcac cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004643             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:4969:6979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004643
VERSION     KCWK01004643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:4969:6979"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70381.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          162 c          124 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcggtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tatatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004644             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:22239:19167
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004644
VERSION     KCWK01004644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22239:19167"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..287
                     /note="immunoglobulin light chain variable region"
     V_region        8..287
     V_segment       8..250
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <212..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70382.1"
                     /translation="DYYCAAWDDSLSSLFF"
     J_segment       252..287
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>325
                     /gene="IGLC"
BASE COUNT           67 a          100 c           79 g           79 t
ORIGIN      
        1 acatggggtc accatctctt gctctggaag cagctccaac attggaagta attatgtata
       61 ctggtaccag cagctcccag gaacggcccc caaactcctc atctattata ataatcagcg
      121 accctcaggg gtccctgacc gattctctgg ctctaagtct ggcacttcag cctccctggc
      181 catcactggt ctccgatctg aggatgaggc tgattattac tgtgcagcat gggatgacag
      241 cctgagcagt ttgttcttcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc
      301 tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004645             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:4807:9973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004645
VERSION     KCWK01004645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:4807:9973"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70383.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          151 c          122 g          113 t
ORIGIN      
        1 acatgggggc ttggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagtagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatggagg cagcaatagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004646             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:5892:4331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004646
VERSION     KCWK01004646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5892:4331"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70384.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           91 a          139 c          134 g          104 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggaaag acggccagga tcacctgtgg gggagacaat
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tattgatcat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctaccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004647             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:19198:3249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004647
VERSION     KCWK01004647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19198:3249"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..433
                     /note="immunoglobulin light chain variable region"
     V_region        88..433
     V_segment       88..396
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70385.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           91 a          160 c          110 g          110 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccacc ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttga gcagtggcaa tgttggtagt
      181 tacagcatat tctggtacca gcagaagcca gggagtcctc cccggtacct tctttactac
      241 tactcagact caactaagca ccaggactct ggagtcccca gccgcttctc tggatcgaaa
      301 gatgcttcag ccaatgcagg gcttttactg atctctgggc tccagtctga agatgaggct
      361 gactattact gtgccacatg gcacagcagc gcttcttaca tcttcggtgc tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01004648             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:12491:9942
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004648
VERSION     KCWK01004648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12491:9942"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70386.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          163 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgc ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004649             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:19311:13040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004649
VERSION     KCWK01004649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19311:13040"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70387.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          141 c          138 g          101 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accagcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004650             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:22746:17763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004650
VERSION     KCWK01004650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22746:17763"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70388.1"
                     /translation="DYYCQVWDIYFDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          143 c          136 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaggccac cgcaggcccc tgtgctggtc
      241 atctatgctg attgtgaacg gccctcaggg gtccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgagcccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta ttttgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004651             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:19613:16385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004651
VERSION     KCWK01004651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19613:16385"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70389.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       390..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           86 a          138 c          136 g          102 t
ORIGIN      
        1 acatggggga ctttgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctttacaggc tctgtggcct cctatgagtt gcctcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtaata gtgtgcattg gtaccagcag aagccaccgc gggcccctgt attggtcatc
      241 tctgttgata gtgaacggcc ctcagggatc cctgagcgat tctctggttc cagatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg ataatattta taaatacgcg gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004652             392 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:17620:21100
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004652
VERSION     KCWK01004652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 392)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17620:21100"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    30..354
                     /note="immunoglobulin light chain variable region"
     V_region        30..354
     V_segment       30..316
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <279..>326
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70390.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       318..354
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        355..>392
                     /gene="IGLC"
BASE COUNT           83 a          122 c          108 g           79 t
ORIGIN      
        1 acatgggtta ctgcacaggc tctgcggcct cctatgatct gactcagcca ccctcggtgt
       61 cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt ggaagtcaaa
      121 gtgtgcactg gtaccagcac aagccaccgc aggcccctgt actggtcatc ttttattata
      181 ccgaacggcc ctcaggaatc cctgagcgat tctctggctc caaatcaggg aacaccgcca
      241 ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt caggtgtggg
      301 acacaactat tgatcacggc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      361 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004653             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:20907:11382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004653
VERSION     KCWK01004653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20907:11382"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70391.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          160 c          121 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcaga tgtatgacag tagtgatgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004654             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:23568:3796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004654
VERSION     KCWK01004654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:23568:3796"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..397
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70392.1"
                     /translation="DYYCSSYAGSNTHWLF"
     J_segment       407..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          159 c          119 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcaggacgtc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa ctacacccag gcaaagcccc
      241 caaactcatg atttatgatg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaaatct gacaacacgg cctccctgac catctctggg ctccaggctg aggatgagac
      361 tgattattac tgcagctcat atgcaggcag caacactcat tggcttttcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004655             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:15526:6613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004655
VERSION     KCWK01004655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:15526:6613"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..388
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70393.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          149 c          119 g          108 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc acgatctcct gcagtgggag caactccaac
      181 attggatatt attatgtgca gtggtaccag cagcttccag gaacggcccc caaactcctc
      241 atctatgaaa ataataagcg accctctggg gtttctgatc gattctctgg ctcccagtct
      301 ggtacctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgccactcct atgacagcag tttgagtggt gtcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tcccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004656             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:28115:15116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004656
VERSION     KCWK01004656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:28115:15116"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..350
                     /note="immunoglobulin light chain variable region"
     V_region        20..350
     V_segment       20..311
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <275..>322
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70394.1"
                     /translation="VYYCGAWDSSLSGYIF"
     J_segment       313..350
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        351..>388
                     /gene="IGLC"
BASE COUNT           74 a          122 c          106 g           86 t
ORIGIN      
        1 acatgggggg tcctgggccc agtctgtgct gacgcagccg ccctcagtgt ctacggcccc
       61 agggcagaag gtcaccatct cctgctctgg aagtagctcc aacatcggga gaaattctgt
      121 atcctggtac cagcaggtcc caggaacggc ccccaaagtc ctcatctatg acaataataa
      181 gcgcccctcg ggggtttctg accgattctc tggctccaag tctggtacct cagcctccct
      241 ggccatcact ggactccagg ctggagatga ggctgtttat tactgcggag catgggatag
      301 cagtctgagt ggttacatct tcggtgatgg gacccggctc accgtcctag gtcagcccaa
      361 ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01004657             386 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:13741:17691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004657
VERSION     KCWK01004657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 386)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13741:17691"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    18..348
                     /note="immunoglobulin light chain variable region"
     V_region        18..348
     V_segment       18..310
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <273..>320
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70395.1"
                     /translation="DYYCASWDDNLSGYIF"
     J_segment       312..348
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        349..>386
                     /gene="IGLC"
BASE COUNT           78 a          125 c           94 g           89 t
ORIGIN      
        1 acatggggtc ctgggcccag tctgtgctga ctcagcctcc ctcagcgtct gaggccgcca
       61 ggaagagtgt caccatctcc tgttctggaa gcacctccaa catcggaagc aataatgtat
      121 cctggtacca gcagctccca ggaacagctc ccaaactcct cttttattat aatgatcaac
      181 gagcctcagg tgtctctgac cgattctctt gctccaagtc tggcacgtca gcctccctgg
      241 ccatcagtgg gctccagacc gaggatgagg ctgattatta ctgcgcatca tgggatgata
      301 acctgagcgg ctacatcttc ggtgctggga cccggctcac cgtcctaggt cagcccaagg
      361 cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004658             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:8616:17470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004658
VERSION     KCWK01004658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8616:17470"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70396.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          148 c          127 g           98 t
ORIGIN      
        1 acatggggct gggcctcatg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tatactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004659             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:25638:6725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004659
VERSION     KCWK01004659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:25638:6725"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70397.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          144 c          138 g           93 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tggaagtgaa gttgtgaact tgtaccagca gaagccagcg cacgcccctg tgctggtcat
      241 ctatgctaat agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg ggtgaggctg actattactg
      361 tcaggtgtgg gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004660             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:16692:15855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004660
VERSION     KCWK01004660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16692:15855"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70398.1"
                     /translation="DYYCQVWDSTSDHVFF"
     J_segment       388..424
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           87 a          141 c          137 g           97 t
ORIGIN      
        1 acatgggggg gcccaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagccg
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacgacatt
      181 ggaagtaaat atgtgcactg gtaccagcag aagccaccgc aggcccctgt gctggtcatc
      241 tattatgatg gcgaacggcc ctcagggatc cctgagcgat tctctgactc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtactag tgatcatgtg tttttcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004661             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:15887:6804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004661
VERSION     KCWK01004661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15887:6804"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..396
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70399.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       398..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           94 a          152 c          116 g          109 t
ORIGIN      
        1 acatggggtc tggagccagg gatcccttcc aatatcagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcacctgtgc ttccagcact
      181 ggagcagtca ccagtggtca ctctccacac tggttccagc agaaacctgg acaagccccc
      241 aagacactga tttataatac aaactacaga cacccctgga ctcctgcccg gttctcaggc
      301 tccctccttg ggggtaaagc tgccctgaca ctgtcaggtg cgcagcctga ggatgaggct
      361 gagtattatt gtttactgta ctatagtggt gctcagctgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004662             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:22969:10345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004662
VERSION     KCWK01004662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22969:10345"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70400.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       403..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           92 a          162 c          110 g          113 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgacccagcc aacctccctc
      121 tcagcatctc cgggagcatc agccagactc agctgcacct ttagcagtgg catcaatgtt
      181 ggtagttaca gcatattctg gtaccagcag aagccaggga gtcctccccg gtaccttctc
      241 tactactact cagactcaag taaacaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcggccaa tgcaggcctt ttactgatct ctgggctcca gtctgaagat
      361 gaggctgact attactgtgc catatggcac agcagcgctt cttacttctt cggtactggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01004663             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17195:10437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004663
VERSION     KCWK01004663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17195:10437"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70401.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       396..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           93 a          155 c          116 g          106 t
ORIGIN      
        1 acatgggggg ggtacagaag gcaggactca ggacaatctc cagcatggcc tggttccctc
       61 tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg ctgactcagc
      121 ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct ggaagcacct
      181 ccaacatcgg aagcaataat gtatcctggt accagcagct cccaggaaca gctcccaaac
      241 tcctctttta ttataatgat caacgagcct caggtgtctc tgaccgattc tcttgctcca
      301 agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat gaggctgatt
      361 attactgcgc atcatgggat gataccctga gcggctacat cttcggtgct gggacccggc
      421 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004664             500 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:12649:17925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004664
VERSION     KCWK01004664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 500)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12649:17925"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    138..462
                     /note="immunoglobulin light chain variable region"
     V_region        138..462
     V_segment       138..413
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <387..>434
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70402.1"
                     /translation="AYYCQVWDSDTDHYIF"
     J_segment       425..462
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        463..>500
                     /gene="IGLC"
BASE COUNT          101 a          161 c          140 g           98 t
ORIGIN      
        1 acatggggga ggataagaga agcctggaag gcacctgccc tgtctgggtc tcaggaggca
       61 gcattgacgg tgcctcagcc atggcctgga cccttctcct cctcggcctc ctcgctcact
      121 gcacagcctc tgcgacctcc tatgagctga ctcagccacc ctcggtgtca gcggcctcag
      181 gacagacggc caggatcacc tgtgggggag acaacatcgg aactagtttt gtgcactggt
      241 accagcagaa gccagcgcag gcccctatac aggtcatcta tgctgatacc aaacggccct
      301 cagggatccc tgagagattc tctggctcca actcagggaa caccgccacc ctgaccatca
      361 gcggagtcga ggccggggat gaggctgcct attactgtca ggtgtgggac agtgatactg
      421 atcattacat cttcggtgct gggacccggc tcaccgtcct aggtcagccc aaggcttccc
      481 ccacggtcac tctgttcccg
//
LOCUS       KCWK01004665             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:12618:17734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004665
VERSION     KCWK01004665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12618:17734"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70403.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          140 c          137 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01004666             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:15997:9639
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004666
VERSION     KCWK01004666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15997:9639"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70404.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       398..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          167 c          120 g          100 t
ORIGIN      
        1 acatggggca gcagagccct gaggagtctg caccatggcc tggaccccaa tcctcctcct
       61 cctcctcact ctcctccttc actgcacagg gtctctctcc cagcctgtgc tgactcagtc
      121 gccctctgcc tctgcctccc tgggagcctc ggtcaagctc acctgcactc tgagcagtgg
      181 ccactacagc tacaccatcg catggcatca gcagcaacaa gggaaggccc ctcggttctt
      241 gatgtggctt aagaatgatg gcagccacac caagggggac ggggtccctg atcgcttctc
      301 aggctccagc tccggggctg agcgctacct caccatctcc aacctccagt ctgaggatga
      361 ggctgattat tactgtcaga cctgggacat tggcatttgg gtattcggcg gagggacccg
      421 cctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004667             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:19797:7304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004667
VERSION     KCWK01004667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19797:7304"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..440
                     /note="immunoglobulin light chain variable region"
     V_region        92..440
     V_segment       92..401
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70405.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       403..440
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           96 a          155 c          110 g          117 t
ORIGIN      
        1 acatgggact gcagggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc gcagcctgtg ctgactcagc caacctccct
      121 ctcagcttct cctggagcat cagccagact cacctgcacc ttgaacagtg gcatcagtgt
      181 tgctaattac aggatattct ggtaccacca gaagccaggg agtcctcccc ggtatcttct
      241 gaactaccac acagactcag atattcacca gggctctgga gtccccagcc gcttctctgg
      301 atccaaagat gcttcggcca atgcagggat tttactcatc tctggactcc agtctgagga
      361 tgaggctgac tattactgta tgatttggca caacaatgct tattgggttt tcggcggagg
      421 gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004668             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18736:9637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004668
VERSION     KCWK01004668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18736:9637"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..398
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70406.1"
                     /translation="DYYCQSHDTSSVFF"
     J_segment       399..435
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           82 a          161 c          126 g          104 t
ORIGIN      
        1 acatgggggg ctgtggctca ggaagcagag cctggagcat ctccaccatg gcctgggctc
       61 cactcctcct caccctcctc gctcactgca cagggtcttg ggctgaggtt gtgttcactc
      121 agccccattc tgtgtcgggg tctccggggc agacggtcac catctcctgc acccgcagca
      181 gtggcagcat tgacaacagt tttgtgtact ggtaccagca gcggccgggc agcgccccca
      241 ccactgtgat ttacgcagat aaccaaagac cctctggggt ccctgatcgg ttctctggct
      301 ccatcgacag ctcctccaac tctgcctccc tcaccatctc tggactgaag tctgaggacg
      361 aggctgacta ctactgtcag tctcatgaca ccagcagtgt gtttttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004669             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:23930:16019
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004669
VERSION     KCWK01004669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:23930:16019"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70407.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           89 a          152 c          121 g          111 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgtagctca tatgcaggca gcaacagttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004670             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:9182:17582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004670
VERSION     KCWK01004670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:9182:17582"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70408.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          164 c          123 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggatga ggccgactat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004671             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:10368:19136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004671
VERSION     KCWK01004671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10368:19136"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..237
                     /note="immunoglobulin light chain variable region"
     V_region        8..237
     V_segment       8..197
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <165..>209
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70409.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       200..237
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>275
                     /gene="IGLC"
BASE COUNT           56 a           83 c           72 g           64 t
ORIGIN      
        1 acatggggaa gccagggagt cccccccggt atcttctgag gtacaaatca gactcagata
       61 agggcctggg ctctggagtc cccagccgct tctctggatc caaagatgct tcagcgaata
      121 cagggatttt acacatctct ggtttccagt ctgaggatga ggctgactat tactgtgcca
      181 ttggccacgg cagcggtgat tacatcttcg ctactgggac ccggctcacc gtcctaggtc
      241 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004672             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:13109:15412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004672
VERSION     KCWK01004672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:13109:15412"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70410.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          143 c          135 g          102 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtcaa ctggtaccaa cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgcggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tactgatcat ccggtgttgt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004673             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:22138:9550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004673
VERSION     KCWK01004673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22138:9550"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..401
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70411.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       406..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           90 a          155 c          119 g          110 t
ORIGIN      
        1 acatggggct gggatctcag gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccccgact
      121 cagactccct ctgtgtccgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgata ttgggtatta tcatgctgtg tcttggtacc aacatcatcc aggcaaagcc
      241 cccaaactca tgatttatga ggtcaataaa cggcccgcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccagac tgaggatgag
      361 gctgattatt actgcagctc atatgcaggc agcaacactt tattcttcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004674             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:20082:5039
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004674
VERSION     KCWK01004674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20082:5039"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70412.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           87 a          144 c          137 g           98 t
ORIGIN      
        1 acatgggagc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactttac agtctctgcg gcctcctctg agctgactca
      121 gccacgctca gtgtccgtct ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt agaagtgtgc agtggtacca gcagaagcca ccgcaggccc ctgtgctggt
      241 catctatgtt gatagcggac ggccctcagg gatccctgag cgattctctg gctccaattc
      301 agggaacacc gccaccctga ccatcagcgg cgtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggatagta gtagtaaata cgtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004675             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:24199:8176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004675
VERSION     KCWK01004675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24199:8176"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..431
                     /note="immunoglobulin light chain variable region"
     V_region        104..431
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70413.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       395..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          144 c          135 g          102 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt gaagttgtca actggtacca acagaagcca ccgcaggccc ctgtggtggt
      241 catctatgct gattatgaac ggccctcagg gatccctgac cgattctctg gctccaaatc
      301 agggaacacg gccaccctga ccatcagcgg agtcgcggcc ggggatgagg ctgactatta
      361 ctgtcaggtt tgggacattt atactgatca tccggtgttg ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004676             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:16940:2580
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004676
VERSION     KCWK01004676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:16940:2580"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70414.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          162 c          119 g          108 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgaccagt ggcgtcaatg
      181 tgggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacca gtcagactca aggaagcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc tgttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccctatggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004677             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:15292:19861
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004677
VERSION     KCWK01004677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:15292:19861"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70415.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          144 c          140 g           92 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttggaagtga agttgtgaac tggtaccagc agaagccagc gcacgcccct gtgctggtca
      241 tctatgctaa tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg gggtgaggct gactattact
      361 gtcaggtgtg ggacatgcgt agtgatcaac cgctattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004678             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:25541:18156
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004678
VERSION     KCWK01004678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25541:18156"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70416.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          161 c          121 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actccgccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcaga tgtatgacag tagtgatgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004679             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12202:5981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004679
VERSION     KCWK01004679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12202:5981"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70417.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       388..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           95 a          148 c          127 g           91 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcttg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgaa ctcctatgag ctgactcagc
      121 caccctcagt gtcagcggcc tcaggacaga cggccaggat cacctgtcgc ggagacaaca
      181 ttggaattaa aaatgtacac tggtaccacc agaagccacc gcaggcccct gtgctggtca
      241 tctttgctga taacaaacgg ccctcaggga tccctgagcg attctctgcc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatggg tattcggcgg agggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004680             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:7013:6696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004680
VERSION     KCWK01004680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:7013:6696"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70418.1"
                     /translation="DYYCAIWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          160 c          112 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc atcaatgttg
      181 gtagttacag ctttttctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agagtcaagt aaccaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004681             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:13050:11007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004681
VERSION     KCWK01004681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13050:11007"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70419.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          142 c          133 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc ccggacagac ggccaggatc acctgtggag gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tgctggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccgactgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004682             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:11692:14724
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004682
VERSION     KCWK01004682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11692:14724"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..266
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <230..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70420.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       271..305
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           70 a          102 c           90 g           81 t
ORIGIN      
        1 acatgggggg gcgcccgggc agagggtcac gatctcctgc agtgggagca actccaacat
       61 tggatattat tatgtgcagt ggtaccagca gcttccagga acggccccca aactcctcat
      121 ctatgaaaat aataagcgac cctctggggt ttctgatcga ttctctggct cccagtctgg
      181 tacctcagcc tccctgacca tcactggact ccagtctgag gatgaggctg attattactg
      241 ccactcctat gacagcagtt tgagtggtgt cttattcgga ggagggaccc ggctgaccgt
      301 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004683             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:15863:21876
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004683
VERSION     KCWK01004683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15863:21876"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70421.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           82 a          163 c          115 g          115 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 caccagtgac gttggtggtt ctaattctgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaagtc atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagt ctgaggacga
      361 ggctgattat tactgttgtt cacattcaac cagtagcact tacgtcttcg gtcctgggac
      421 ccggctcacc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004684             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:16944:10538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004684
VERSION     KCWK01004684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:16944:10538"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70422.1"
                     /translation="DYYCDSWDSSGTHWIF"
     J_segment       396..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          140 c          128 g          105 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagagctct ggggtgtctc caccatggcc tggactcctc
       61 tctggctcac cctcctcagt ctttgcacag gttctgtggt ttcttctgag ctgactcagg
      121 accctgcagt gtctgtggcc ttgggacaga cagtcaggat cacctgccaa ggagacaccc
      181 tcagaagttg ttatgcaaac tggtaccaga agaagccagg ccaggcccct gtcctggtcg
      241 tctttggaaa caattaccgg ccctcaggga tcccagaccg attctctggc tccagctcaa
      301 gaaacacagc ttccttgacc atcattgggg ctcaggtgga agatgaggct gactattact
      361 gtgactcctg ggacagcagc ggtacccatt ggattttcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004685             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:11812:14269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004685
VERSION     KCWK01004685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11812:14269"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70423.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           90 a          154 c          119 g          110 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc agtggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcgtcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgaag
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt attcttcgga cgagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004686             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:16064:6834
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004686
VERSION     KCWK01004686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16064:6834"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..389
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70424.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       394..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           88 a          152 c          115 g          107 t
ORIGIN      
        1 acatggggga ggcagcgctc tcaggacttc tccaccatgg tctgggctct gctcctcctc
       61 accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca gactccctct
      121 gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag cagtgatatt
      181 gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc caaactcatg
      241 atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg ctccaagtct
      301 ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc tgattattac
      361 tgcagctcat atgcaggcag caacacttta ttcttcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004687             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:27609:15249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004687
VERSION     KCWK01004687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:27609:15249"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70425.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       398..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          155 c          122 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctaca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagaccc
      241 caaattcatg atttatgagg tcagtcaacg gccctcaggg gtctctgatc gtctctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tggttattac tgcagctcat ttgcaggtac caacactggc ttaatcggtg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004688             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:20917:12881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004688
VERSION     KCWK01004688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20917:12881"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70426.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>468
                     /gene="IGLC"
BASE COUNT           89 a          155 c          119 g          105 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgcccccg
//
LOCUS       KCWK01004689             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:21870:15521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004689
VERSION     KCWK01004689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:21870:15521"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70427.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           88 a          157 c          119 g          112 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgtctacca cgtacactgg taccagcaga agccagggag tcccccccgg tttcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccagtaatgt ttcagcgaac acagggattt tacgcatttc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004690             349 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:5255:10112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004690
VERSION     KCWK01004690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 349)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:5255:10112"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..311
                     /note="immunoglobulin light chain variable region"
     V_region        4..311
     V_segment       4..272
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <239..>283
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70428.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       274..311
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        312..>349
                     /gene="IGLC"
BASE COUNT           77 a          103 c           84 g           85 t
ORIGIN      
        1 acatggggca tcagccagac tcacctgcac cttgaacagt ggcatcagtg ttgctaatta
       61 caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc tgaactacca
      121 cacagactca gatattcacc agggctctgg agtccccagc cgcttctctg gatccaaaga
      181 tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg atgaggctga
      241 ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag ggacccggct
      301 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004691             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:21812:5233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004691
VERSION     KCWK01004691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21812:5233"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..402
                     /note="immunoglobulin light chain variable region"
     V_region        106..402
     V_segment       106..392
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70429.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       393..402
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        403..>431
                     /gene="IGLC"
BASE COUNT           90 a          127 c          117 g           97 t
ORIGIN      
        1 acatggggag ctgtgggctc agaagcagag ctctggggtg tctccaccat ggcctggact
       61 cctctctggc tcaccctcct cagtctttgc acaggttctg tggtttcttc tgagctgact
      121 caggaccctg cagtgtctgt ggccttggga cagacagtca ggatcacctg ccaaggagac
      181 agcctcagaa gttattatgc aagttggtac cagcagaagc caggccaggc ccctatactg
      241 atcgtctatg gtaacaatta ccggccctca gggatcccag agcgattctc tggctccagt
      301 acacgaaaca cagcttcctt gaccatcact ggggctcagg tggaagatga ggctgactat
      361 tactgtgact cctgggacag ccgcggaacc caattcggag gaaggctgcc ccctcggtca
      421 ctctcttccc g
//
LOCUS       KCWK01004692             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:17028:15138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004692
VERSION     KCWK01004692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:17028:15138"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70430.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       414..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           91 a          155 c          128 g          114 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag atttttatgt gcagtggtac cagcaccttc
      241 caggaacggc ccccagactc ctcatctatg aaaataataa gcgaccctca ggggtttctg
      301 atcgattctc tggctcccag tctggaacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagtttgatt gctgtgttat
      421 tcggaggagg gacccggttg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01004693             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15207:10208
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004693
VERSION     KCWK01004693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15207:10208"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70431.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          155 c          129 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accgtctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctatgaaa atgataaacg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct gattcctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cttgagtgtt gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004694             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:20049:4026
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004694
VERSION     KCWK01004694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20049:4026"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..418
                     /note="immunoglobulin light chain variable region"
     V_region        94..418
     V_segment       94..377
                     /gene="IGLV3-35"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <343..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70432.1"
                     /translation="DYYCGSWDNSDKRYIF"
     J_segment       381..418
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>456
                     /gene="IGLC"
BASE COUNT           92 a          138 c          121 g          105 t
ORIGIN      
        1 acatggggag aagcagaact ctgggtcgtc tccaccatgg cctggacccc tcccctgctc
       61 atcctcctca ctctctgcac aggttccgtg gtttcctctg ggctgactca ggagcctgca
      121 ttgtctgtgg ccttgggaca tacagtcagg atgacctgcc aaggagacag cctcaaaacc
      181 tattacgcaa gctggtatca gcagaagcca ggccaggtcc ctgtgctggt catctatggt
      241 aacaccaata ggccctcagg gatcccaggc cgattctctg gctcctggtc aggaaactca
      301 ggttccttga ccatcactgg ggctcaggtg gaagatgagg ctgactatta ctgtggctcc
      361 tgggataaca gtgataagcg ttacatcttc ggtgatggga cccggttcac cgtcctaggt
      421 cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004695             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:12300:12547
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004695
VERSION     KCWK01004695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:12300:12547"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70433.1"
                     /translation="DYYCAIGHSSGYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          158 c          119 g          107 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggctccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagtggt ggcatcaatg
      181 ttgctggcta ccacacacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccagaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004696             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:17425:11951
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004696
VERSION     KCWK01004696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17425:11951"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70434.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           88 a          155 c          121 g          112 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgtctacca cgtacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggggt ccccagccgc ttctctggat
      301 ccagtaatgg ttcagtgaac acagggattt tacgcatttc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtct ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004697             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:23996:9182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004697
VERSION     KCWK01004697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:23996:9182"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70435.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          160 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcat tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacga tagtgctgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004698             450 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:24578:15504
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004698
VERSION     KCWK01004698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:24578:15504"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    64..412
                     /note="immunoglobulin light chain variable region"
     V_region        64..412
     V_segment       64..375
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70436.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       376..412
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>450
                     /gene="IGLC"
BASE COUNT           84 a          155 c          110 g          101 t
ORIGIN      
        1 acatgggtgg ccctgactcc tctcctcctc ctgctcctct ctcactgcac aggttccctc
       61 tcccagcctg tgctgactca gccaccctcc ctgtctgcgt ccccgggagc atcggccaga
      121 ctcccctgca ccctgaccag tgacctcagc gttggtagta aaaacatgta ttggtaccag
      181 cagaagccag ggagcgctcc caggtcattc ctctactact actccgactc agacaagcag
      241 ctgggacctg gggtccccaa tcgagtctct ggctccaagg agacctcaag taacacagcg
      301 tttttgctca tctctgggct ccagcctgag gacgaggccg actattactg tcaggtgtat
      361 gacagtagtg ctaatgtgtt attcggagga gggacccggc tgaccgtcct aggtcagccc
      421 aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004699             342 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:28963:16286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004699
VERSION     KCWK01004699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 342)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:28963:16286"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    2..304
                     /note="immunoglobulin light chain variable region"
     V_region        2..304
     V_segment       2..265
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <232..>276
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70437.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       274..304
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        305..>342
                     /gene="IGLC"
BASE COUNT           73 a          109 c           83 g           77 t
ORIGIN      
        1 acatgggggg cccccggaca gagggtcacc atctcctgca ttagcagcag ctccaacatc
       61 ggggcggctt attatgtatc ctggtaccaa cagttcccag gaacagcccc caaactcctc
      121 atctttgaaa ataataagcg accctcaggg gtttctgacc gaatctctgg ctccaagtct
      181 ggtccctcag cctccctgac catcactgga ctccaatctg aggatgaggc tgattattac
      241 tgtttagcat gggataccag cctgaattgg atcttcggcg gagggacccg gctgaccgtc
      301 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004700             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:24052:4668
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004700
VERSION     KCWK01004700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24052:4668"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70438.1"
                     /translation="DYYCSAWDSSLTGGLF"
     J_segment       407..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           96 a          156 c          124 g          106 t
ORIGIN      
        1 acatggggca gcttcagctg tggctagaga agacaggact caggacaatc tccagcatgg
       61 cctgcttccc tctcatcctc accgtcctca ctcactgtgc aggatcctgg gcccagtctg
      121 tgctgactca accaccctca gcgtctgggg cccccgggca gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaatt atgtatactg gtaccagcag ttctcaggga
      241 aggcccccaa actcctcatc cataataata atcagcgacc ctcaggggtc cctgatcgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagtccgagg
      361 atgaggctga ttattactgc tcagcgtggg atagcagtct gaccggtggc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004701             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:27491:8826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004701
VERSION     KCWK01004701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:27491:8826"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70439.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       409..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           97 a          153 c          117 g          113 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggagc atcagccagt ctcacatgca ccttcaacgg tggcatcact
      181 gttgctggct accatatata ttggtaccaa cagaagccag ggagtccccc ccggtatctt
      241 ctgaggtaca aatcagactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc gaacacaggg attttacgca tatctggact ccagtctgag
      361 gatgaggctg actattactg tgccattgga cacagcagcg gtgattatat cttcggtggt
      421 gggacccgtc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004702             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:11167:4327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004702
VERSION     KCWK01004702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11167:4327"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70440.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          138 c          135 g          105 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 cttctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggaaag acggccagga tcacctgtgg gggagacaat
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tattgatcat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004703             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:20033:15717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004703
VERSION     KCWK01004703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20033:15717"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..434
                     /note="immunoglobulin light chain variable region"
     V_region        107..434
     V_segment       107..402
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70441.1"
                     /translation="DYYCSSYAGSKTLF"
     J_segment       403..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          157 c          123 g          104 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acaggcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtgctt ataactatgt ctcctggtac cagcagcacc caggcaaagc
      241 ccccaaactc atgatttatg atgtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaaaacg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004704             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:18261:4368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004704
VERSION     KCWK01004704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18261:4368"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70442.1"
                     /translation="DYYCAAWDESLRGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          155 c          127 g          103 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgcgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tgggagcagc tccaacatcg gaagaaatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa atcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagccgc cctggccatc agcgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgaaagcctg aggggttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01004705             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:3954:10040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004705
VERSION     KCWK01004705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:3954:10040"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70443.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           87 a          143 c          135 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcactgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagcggccac cgcaggcccc tgtgctggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaagtca
      301 gggaacacgg ccaccctgac catcagggga gtcgaggcct gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004706             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12009:6236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004706
VERSION     KCWK01004706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12009:6236"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70444.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       412..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           91 a          155 c          128 g          113 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg agcagctcca acattggagg ttattatgtg cagtggtacc aacagcttcc
      241 aggaacggcc cccaaactcc tcatctatga aaatgataaa cgaccctcag gggtttctga
      301 tcgattctct ggctcccagt ctgattcctc agcctccctg accgtcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agcttgagtg ttgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01004707             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:20038:8090
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004707
VERSION     KCWK01004707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:20038:8090"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70445.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          145 c          140 g           94 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag cggaagccag cgcaggcccc tgtgctggtc
      241 atctatgctg ataccgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg ggggtgaggc tgactattac
      361 tgtcaggtgt gggacatgcg tagtgatcaa ccgctattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaatgc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004708             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:25990:19180
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004708
VERSION     KCWK01004708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:25990:19180"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70446.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          163 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca aacagctggg acctgaggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004709             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:13904:6930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004709
VERSION     KCWK01004709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13904:6930"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70447.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          162 c          121 g          110 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggta gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcaggtg tatgacagta gtgctaatgt cttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004710             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:16498:4211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004710
VERSION     KCWK01004710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16498:4211"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70448.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          161 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg attcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttgttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004711             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:24706:13834
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004711
VERSION     KCWK01004711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24706:13834"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70449.1"
                     /translation="DYYCQSSHSRVNHPFF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT          103 a          138 c          125 g          101 t
ORIGIN      
        1 acatgggggg ctgtggttct aggaggaaga cctctgggtg tctcaccatg acctggacca
       61 ctgttctgct cccctttctc actctctgca caggctctga ggcctcctat gagctgacac
      121 agccaccctc agtgtcagtg tccccaggac agacggccag gatcacctgc tctggagaaa
      181 cactggcaaa aaaatatgct cagtggttcc agcagaagcc aggccaggcc cctgtgttgg
      241 tgatatataa agacagtgag aggccctcag ggatccctga gcgattctct agctccagtt
      301 cagggacaac agttaccttg accatcagtg gggcccaggc agaagatgag gctgactatt
      361 actgtcaatc atcgcacagc agggttaatc atccgttttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004712             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:26801:19999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004712
VERSION     KCWK01004712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:26801:19999"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70450.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          161 c          119 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatattgg caataaaaac atgtactggt accagcagaa gccagggagc gctcccaagt
      241 tattcctgta ctactactcc gactcagaca tgcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacctg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004713             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:23630:10937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004713
VERSION     KCWK01004713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23630:10937"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..250
                     /note="immunoglobulin light chain variable region"
     V_region        7..250
     V_segment       7..213
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <175..>222
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70451.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       214..250
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        251..>288
                     /gene="IGLC"
BASE COUNT           56 a           89 c           76 g           67 t
ORIGIN      
        1 acatggggaa gtcatagtgt ctcctggtac cagcaagtcc caggaacagc tcccaaactc
       61 ctcatctatt atagtgatca acgagcctca ggtgtctctg accgattctc tggctctcag
      121 tctggcacgt cagcctccct ggccatcagt gggctccaga ccgaggatga ggctgattat
      181 tactgcgcag catgggatga tagcctgagg ggttacatct tcggtgctgg gacccggctc
      241 gccgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01004714             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:17197:6619
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004714
VERSION     KCWK01004714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17197:6619"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70452.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          143 c          132 g           96 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca cagtctctgc gacctcctat gaactgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc agcagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgatagtaaa cggccctcag ggattcctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004715             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:18937:13812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004715
VERSION     KCWK01004715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18937:13812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..376
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70453.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       388..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          146 c          131 g           96 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctttgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaattaaa tttgtccact ggtaccagca gaagccagcg caggcccctg tgaaggtcat
      241 ctatgctgat gacaaacggc cctcagggat ccctgagaga ttctctggct ccaattcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattcctg
      361 tcaggtgtgg gacagtgaga ctgattatta catcttcggt tctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004716             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:15614:14658
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004716
VERSION     KCWK01004716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15614:14658"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70454.1"
                     /translation="DYYSSSWESSLNWVF"
     J_segment       409..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          152 c          129 g          114 t
ORIGIN      
        1 acatggggga gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctctccttc tcactctgct ggttcactgc acagggtcct gggcccagtc
      121 tgtgttgacg cagccgccct cagcatctgg ggcccccggg cagagggtca ccatctcctg
      181 cactgggagt agctccaaca tcggggcggg tttttatgtt tcctggtacc agcagttccc
      241 aggaacagcc cccaaactcc tcatctttga aaataataag cgaccctcag gggtttctga
      301 ccgattctct ggctccaagt ctggttcctc agcctccctg accatcactg gactccaatc
      361 tgaggatgag gctgattatt attcttcatc atgggaaagc agcctgaatt gggtattcgg
      421 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01004717             393 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:17785:14746
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004717
VERSION     KCWK01004717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 393)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17785:14746"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    25..355
                     /note="immunoglobulin light chain variable region"
     V_region        25..355
     V_segment       25..318
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <280..>327
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70455.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       319..355
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        356..>393
                     /gene="IGLC"
BASE COUNT           76 a          125 c          106 g           86 t
ORIGIN      
        1 acatggggtg cagggtcctg ggcccagtct gtgctgactc agcctccctc agcgtctgag
       61 gccgccagga agagtgtcac catctcctgt tctggaagca gctccaacat cggaaggaat
      121 agtgtatcct ggtaccagca gctcccagga acagctccca aactcctcat ctattatagt
      181 gatcaacgag cctcaggtgt ctctggccga ttctctggct ccaagtctgg cacgtcagcc
      241 tccctggcca tcagcgggct ccagaccgag gatgaggctg attattactg cgcagcatgg
      301 gatgatagcc tgagcggtta catcttcggt gctgggaccc ggctcaccgt cctaggtcag
      361 cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004718             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:13242:12981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004718
VERSION     KCWK01004718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13242:12981"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70456.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       402..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          152 c          121 g          113 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggttcaggct gccccgactc
      121 agcctccccc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat aacgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 ccaaactcat aatttttgac gtcattaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcgacacg gcctccctga ccatctctgg gctccgggct gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gaaataattt tttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004719             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:12928:18401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004719
VERSION     KCWK01004719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12928:18401"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70457.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          154 c          126 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gttccaacat cggaagtaat agtgtatcct ggtatcagca ggtcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagcgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004720             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:12097:6249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004720
VERSION     KCWK01004720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12097:6249"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70458.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       409..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           90 a          154 c          127 g          110 t
ORIGIN      
        1 acatggggag cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtactca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag ccaccctcag cgtctggggc tcccgggcag agtgtcacca tctcttgttc
      181 tggaagcatc tccagcattg gaagtagtga tgtatgttgg taccaacaac tcccaggaac
      241 ggcccccaaa ctcctcatca attatagtga tcagcgactc tcaggggtcc ctgaccgatt
      301 ctctggctct aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga
      361 tgaggctgat tattactgtg cagcctggga tagcagcctg agcagtccgg tattcggcgg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01004721             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:19238:2665
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004721
VERSION     KCWK01004721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19238:2665"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70459.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       412..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           90 a          157 c          130 g          107 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcctcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aagagtgtca ccatctcctg
      181 ttctggaagc agctccaaca tcggaagtaa tagtgtttcc tggtaccagc agctcccaga
      241 aacggctccc aaactcctca tcttttataa tgatcggcga gcctcaggtg tctctgaccg
      301 attctctggc tccaagtctg gcacgtcagc ctccctggcc atcagtgggc tccagaccga
      361 ggatgaggct gattattact gcgcagcatg ggatgatagc ctgagcggtc cggtattcgg
      421 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01004722             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:11615:18028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004722
VERSION     KCWK01004722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11615:18028"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70460.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           96 a          154 c          112 g          115 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcg cagcctgtgc tgactcagcc aacctccctc
      121 tcagcatctc ctggagcatc agccagactc acctgcacct tgaacagtgg catcagtgtt
      181 gctaattaca ggatattctg gtaccaccag aagccaggga gtcctccccg gtatcttctg
      241 aactaccaca cagactcaga tattcaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcggccaa tgcagggatt ttactcatct ctggactcca gtctgaggat
      361 gaggctgact attactgtat gatttggcac aacaatgctt attgggtttt cggcggaggg
      421 acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004723             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:15837:10610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004723
VERSION     KCWK01004723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15837:10610"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70461.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          159 c          121 g          112 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcaattttg gaaataaaaa catatactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagttgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtcat acagcgtttt tgctcatttc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgacg atagtgctgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004724             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:14114:20390
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004724
VERSION     KCWK01004724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14114:20390"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70462.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          143 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc agccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004725             278 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:23959:6767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004725
VERSION     KCWK01004725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 278)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23959:6767"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..240
                     /note="immunoglobulin light chain variable region"
     V_region        10..240
     V_segment       10..200
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <162..>212
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70463.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       204..240
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        241..>278
                     /gene="IGLC"
BASE COUNT           56 a           82 c           80 g           60 t
ORIGIN      
        1 acatgggcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc atctatgctg
       61 attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca gggaacacgg
      121 ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattac tgtcaggttt
      181 gggacattta tattgatcat ccggtgttat tcggaggagg gacccggctg accgtcctag
      241 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004726             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:8818:15157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004726
VERSION     KCWK01004726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8818:15157"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70464.1"
                     /translation="DYYCQVWDTTLDHGLF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           89 a          148 c          128 g           97 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtcaaa gtgtgcactg gtaccagcac aagccaccgc aggcccctgt tctggtcatc
      241 ttttattata ccgaacggcc ctcaggaatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acacaactct tgatcacggc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004727             328 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:6871:6413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004727
VERSION     KCWK01004727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 328)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6871:6413"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..290
                     /note="immunoglobulin light chain variable region"
     V_region        8..290
     V_segment       8..253
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>262
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70465.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       254..290
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        291..>328
                     /gene="IGLC"
BASE COUNT           70 a           98 c           95 g           65 t
ORIGIN      
        1 acatggggga cagacggcca ggatcacctg tgggggagac aacattggaa gtaagagtgt
       61 gcactggtac cagcacaagc caccgcaggc ccctatcctg gtcatctatt attataccga
      121 acggccctcg gcgatccctg agcgattctc tggctccaaa tcagggaaca ccgccaccct
      181 gaccatcagc ggggtcgagg ccggggatga ggctgactat tactgtcagg tgtgggacac
      241 tactattgat catggctttt tcggaggagg gacccggctg accgtcctag gtcagcccaa
      301 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004728             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:5351:5209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004728
VERSION     KCWK01004728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5351:5209"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70466.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       403..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           85 a          162 c          126 g           98 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtggt gactcagtcg
      121 tcctctgcct ctacctccct gggagcctcg gtcaagctca cctgcactct gagcggtggg
      181 cacagcgact acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggtatttg
      241 atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctga tcgcttctcc
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggagact ggcattcagg tgttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004729             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:14656:10443
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004729
VERSION     KCWK01004729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14656:10443"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70467.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          158 c          125 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004730             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:21750:5285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004730
VERSION     KCWK01004730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21750:5285"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70468.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          158 c          126 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004731             336 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:18731:11109
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004731
VERSION     KCWK01004731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 336)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18731:11109"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..294
                     /note="immunoglobulin light chain variable region"
     V_region        8..294
     V_segment       8..261
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <217..>270
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70469.1"
                     /translation="DYHCSAGFGSGYSWQWVF"
     J_segment       262..294
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        295..>336
                     /gene="IGLC"
BASE COUNT           72 a           99 c           98 g           67 t
ORIGIN      
        1 acatgggcag gacagacagc cagcatcacc tgctctggag ataaattggg gaatgtttat
       61 gcttattggt accagcagaa gccaggccag gcccctatac tggtcatcta caaagatagc
      121 aaccggccct cagggatccc tgaccgattc tctggctcca actcagggaa cacggccacc
      181 ctgaccatca gcagggtcga ggctggggat gaggccgact atcactgttc tgcaggcttt
      241 ggcagtgggt acagctggca gtgggttttc ggcggaggga cccggctaac cgtcgtaggt
      301 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004732             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:17754:10428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004732
VERSION     KCWK01004732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17754:10428"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70470.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          161 c          116 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 ctgcatctcc tggagcttca gccagtctca catgcacctt caccggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatataaatc agactcagat aaggaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ctcagcgaac acggggcttt tgcgcatctc tgggctccag tctgaggatg
      361 aggctgacta ctactgtgcc attggacaca gcagcggtga ttacatcttc ggtgctggga
      421 cccgcctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004733             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:5784:9454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004733
VERSION     KCWK01004733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5784:9454"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..341
                     /note="immunoglobulin light chain variable region"
     V_region        13..341
     V_segment       13..307
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70471.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       308..341
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        342..>381
                     /gene="IGLC"
BASE COUNT           65 a          130 c           91 g           95 t
ORIGIN      
        1 acatgggggg ctcagtctgc cccgactcag cctccctctg tgtctgggtc tcctggacag
       61 tcggtcacca tctcctgcac tggaaccagc agtgacgttg gtggttctaa ctctgtctcc
      121 tggtaccaac aacacccagg cagagccccc aaactcatga tttttggtgt caataatcgg
      181 ccctctgggg tctctgaccg cttctctggc tccaagtctg gcaacacggc ctccctgacc
      241 atctctggcc tccagtctga ggacgaggct gattattact gttgttcaca ttcaaccagt
      301 agcacttacg tcttcggtcc tgggacccgg ctcaccgtcc tgggtcagcc caaggcttcc
      361 cccacggtca ctctgttccc g
//
LOCUS       KCWK01004734             294 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:8094:16565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004734
VERSION     KCWK01004734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 294)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8094:16565"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..256
                     /note="immunoglobulin light chain variable region"
     V_region        7..256
     V_segment       7..213
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <178..>228
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70472.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       219..256
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        257..>294
                     /gene="IGLC"
BASE COUNT           65 a           90 c           66 g           73 t
ORIGIN      
        1 acatgggggg cgggttatta tgtatcctgg taccagcagt tcccaggaac agcccccaaa
       61 ctcctcatct atgaaaataa taaacgaccc tcaggggttt ctgaccgatt ctctggctcc
      121 aagtctggta cctcagcctc cctgaccatc actggactcc aatctgagga tgaggctgat
      181 tattactgct cagcatggga tagcagcctg agtatcaatt acatcttcgg ttctgggacc
      241 cgtctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004735             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:20643:16763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004735
VERSION     KCWK01004735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20643:16763"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..423
                     /note="immunoglobulin light chain variable region"
     V_region        101..423
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70473.1"
                     /translation="AYYCQVWDLNSHHLLF"
     J_segment       390..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>463
                     /gene="IGLC"
BASE COUNT           85 a          142 c          137 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccagggtc acctgtgggg gagacaacat
      181 cggaggtgaa gttgtgaatt ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccgga gatgaggctg cctattactg
      361 tcaggtgtgg gaccttaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctgggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004736             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:7133:9808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004736
VERSION     KCWK01004736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7133:9808"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..396
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70474.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       397..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           90 a          154 c          121 g          106 t
ORIGIN      
        1 acatgggggg gtctcaggag gcggcactct cgggacatct ccaccatggc ctgggatctg
       61 ctcctcttca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 cctccctcaa tgtctgggtc tcctggacag tcggtcacca tctcctacac tggaaccagc
      181 agtgacattg gtggttataa ccgtgtctcc tggtaccaac agcacccagg caaagacccc
      241 aaattcatga tttatgaggt cagtcaacgg ccctcagggg tctctgatcg tatctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 ggttattact gcagctcatt tgcaggtacc aacactggct taatcggtgg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004737             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:27384:10513
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004737
VERSION     KCWK01004737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:27384:10513"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..282
                     /note="immunoglobulin light chain variable region"
     V_region        4..282
     V_segment       4..245
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <210..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70475.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       246..282
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>320
                     /gene="IGLC"
BASE COUNT           64 a           98 c           78 g           80 t
ORIGIN      
        1 acatgggcag tggcatcaat gttggtagtt acagcgtatt ctggtaccag cagaagccag
       61 ggagtcctcc ccggttcctt ctgtactact actcagactc aagtaaacac cagggctctg
      121 gagtccccag ccgcttctct ggatccaaag atgcttcggc caatgcaggc cttttactga
      181 tctctgggct ccagtctgaa gatgaggctg actattactg tgccatatgg cacagcagcg
      241 cttcttactt cttcggtact gggacccggc tcaccgtcct aggtcagccc aaggcttccc
      301 ccacggtcac tctgttcccg
//
LOCUS       KCWK01004738             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:22099:22812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004738
VERSION     KCWK01004738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:22099:22812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70476.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          159 c          120 g          106 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 gtgactacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ctctctggat
      301 ccaaagatgc tgcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtcc ttacttcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004739             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:11396:17390
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004739
VERSION     KCWK01004739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11396:17390"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..232
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <197..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70477.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       235..269
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           60 a           94 c           82 g           71 t
ORIGIN      
        1 acatggggtg ggtagttaca gcatattctg gtaccagcag aagccaggga gtcctccccg
       61 gtaccttctg tactaccagt cagactcaag gaagcaccag ggctctggag tccccagccg
      121 cttctctgga tccaaagatg cttcagccaa tgcagggctg ttactgatct ctgggctcca
      181 gtctgaagat gaggctgact attactgtgc cctatggcac agcagcgctt cttgcatctt
      241 cggtggtggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      301 gttcccg
//
LOCUS       KCWK01004740             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:20536:8181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004740
VERSION     KCWK01004740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20536:8181"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..420
                     /note="immunoglobulin light chain variable region"
     V_region        96..420
     V_segment       96..383
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <345..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70478.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       384..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           88 a          145 c          128 g           97 t
ORIGIN      
        1 acatggggtc aggaggcagc attgacggtg cctcagccat ggcctggact tttctcctcc
       61 tcggcctcct tgcttactgc acaggctctg cggcctccga tgatctgact cagccaccct
      121 cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggagac aacattggaa
      181 gtaagagtgt gcactggtac cagcacaagc caccgcaggc ccctatcctg gtcatctatt
      241 attataccga acggccctcg gcgatccctg agcgattctc tggctccaaa tcagggaaca
      301 ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat tactgtcagg
      361 tgtgggacac tactattgat catggctttt tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004741             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:21534:12267
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004741
VERSION     KCWK01004741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21534:12267"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70479.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           98 a          142 c          121 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaagaatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tccagatcat
      241 ctatgaggac agtaaacggc cctctgggat ccctgagaga atctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 tttctcaaca gacaccagtg gtaatcgggt attcggcgga gggacccgtc taaccgtcct
      421 aggtcagccc aaggctgccc tctcggtcac tctcttcccg
//
LOCUS       KCWK01004742             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:9763:16204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004742
VERSION     KCWK01004742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:9763:16204"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..414
                     /note="immunoglobulin light chain variable region"
     V_region        84..414
     V_segment       84..377
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70480.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       378..414
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           84 a          147 c          112 g          109 t
ORIGIN      
        1 acatggggac agtctccagc atggcctggt ctcctctcct cctcaccctt ctcattcact
       61 tcacagttcc agggtcctgg gcccagtctg tgctgacgca gccgccctca gtgtctgggg
      121 cgcccgggca gagggtcacc atctcctgca ctgggagcag ctccaacatt ggagattatt
      181 ttgtgcagtg gtaccagcac cttccaggaa cggcccccaa actcctcatc tatgaaaata
      241 ataagcggcc ctcagggatt tctgatcgat tctctggctc ccagtctgga acctcagcct
      301 ccctgaccat cactggactc cagtctgagg atgaggctga ttattactgc cagtcctatg
      361 acagcagttt gattgctgtg ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004743             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:25303:13648
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004743
VERSION     KCWK01004743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:25303:13648"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70481.1"
                     /translation="DYYCQVYDSSAVFF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           93 a          160 c          116 g          112 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct acatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt aataaaaaca tgtactggta ccaacagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcaactggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caactaacac agtgtttttg atcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt ttatgacagt agtgctgtgt ttttcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01004744             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:18262:7693
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004744
VERSION     KCWK01004744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18262:7693"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70482.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          162 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctgga acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004745             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:18174:11477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004745
VERSION     KCWK01004745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18174:11477"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70483.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       411..447
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          167 c          111 g          117 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg acccagccaa
      121 cctccctctc agcatctccg ggagcatcag ccagactcag ctgcaccttt agcagtggca
      181 tcaatgttgg tagttacagc atattctggt accagcagaa gccagggagt cctccccggt
      241 accttctcta ctactactca gactcaagta aacaccaggg ctctggagtc cccagccgct
      301 tctctggatc caaagatgct tcggccaatg caggcctttt actgatctct gggctccagt
      361 ctgaagatga ggctgactat tactgtgcca tatggcacag cagcgcttct tacttcttcg
      421 gtactgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt
      481 tcccg
//
LOCUS       KCWK01004746             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:20341:2282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004746
VERSION     KCWK01004746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20341:2282"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70484.1"
                     /translation="DYYCQVWDTSIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          147 c          129 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtga gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tatactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgggc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004747             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:11801:19479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004747
VERSION     KCWK01004747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11801:19479"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70485.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          164 c          122 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagcctc
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccgactgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004748             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:11272:12871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004748
VERSION     KCWK01004748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11272:12871"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70486.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          148 c          131 g           95 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 ccctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gttctggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg aatctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaagt cttgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004749             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:15979:9273
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004749
VERSION     KCWK01004749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15979:9273"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70487.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          155 c          127 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaaggaat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg catgtcagcc tccctggcca tcagcgggct ccagaccgag
      361 gatgagggtg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004750             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11168:17409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004750
VERSION     KCWK01004750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11168:17409"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    69..393
                     /note="immunoglobulin light chain variable region"
     V_region        69..393
     V_segment       69..356
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <318..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70488.1"
                     /translation="DYYCQSGDSSGNHWVF"
     J_segment       357..393
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>431
                     /gene="IGLC"
BASE COUNT          103 a          128 c          111 g           89 t
ORIGIN      
        1 acatggggac catgacctgg accactgttc tgctcccctt tctcactctc tgcacaggct
       61 ctgaggcctc ctatgagctg acacagccac cctcagtgtc agtgtcccca ggacagacgg
      121 ccaggatcac ctgctctgga gaaatactgg caaaaaaata tactcagtgg ttccagcaga
      181 agccaggcca ggcccctcta ctggtgatat ataaagacag tgagaggccc tcagggatcc
      241 ctgagagatt ctctaactcc agttcagggc caacagttac cttgaccatc agtggggccc
      301 aggcagaaga tgaggctgac tattactgtc aatcaggaga cagcagtggt aatcattggg
      361 tattcggcgg agggacccgg ctaagcgtcc taggtcagcc caaggctgcc ccctcggtca
      421 ctctcttccc g
//
LOCUS       KCWK01004751             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22993:13169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004751
VERSION     KCWK01004751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22993:13169"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70489.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           92 a          148 c          129 g           97 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt caaagtgtgc actggtacca gcacaagcca ccgcaggccc ctatactggt
      241 catcttttat tataccgaac ggccctcagg aatccctgag cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacacaa ctattgatca cggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004752             353 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:23702:15127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004752
VERSION     KCWK01004752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 353)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23702:15127"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..315
                     /note="immunoglobulin light chain variable region"
     V_region        8..315
     V_segment       8..278
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>287
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70490.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       279..315
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        316..>353
                     /gene="IGLC"
BASE COUNT           76 a          105 c           94 g           78 t
ORIGIN      
        1 acatgggggg agcatcggcc agactcccct gcaccctgag cagtgacctc agtgttggtg
       61 gtaaaaacat gtactggtac cagcagaagc cagggcgcgc tcccaggttt ttcctgtact
      121 acaactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc tctggctcca
      181 aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct gaggacgagg
      241 ccgattatta ctgtcacgta tatgacagta gtactaatgt gttattcgga ggagggaccc
      301 gtctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004753             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:19271:7633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004753
VERSION     KCWK01004753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:19271:7633"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..421
                     /note="immunoglobulin light chain variable region"
     V_region        103..421
     V_segment       103..385
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70491.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       389..421
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           93 a          142 c          130 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaatta aaactgtaca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtaagcc ctcagggatc cctgagcgat tctctggctc caactcaggg
      301 aacaccgcca ccctgaccat cagcagggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag taaatggata ttcggcgggg ggacccggct aaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004754             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:19513:6201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004754
VERSION     KCWK01004754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19513:6201"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70492.1"
                     /translation="DYYCCSRSTSSTYVF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           81 a          163 c          117 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac gttggtggtt atgactctgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaagtc atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagt ctgaggacga
      361 ggctgattat tactgttgtt cacgttcaac cagtagcact tacgtcttcg gtcctgggac
      421 ccgcctcacc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004755             279 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:12811:17011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004755
VERSION     KCWK01004755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 279)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12811:17011"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..241
                     /note="immunoglobulin light chain variable region"
     V_region        8..241
     V_segment       8..203
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <166..>213
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70493.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       204..241
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        242..>279
                     /gene="IGLC"
BASE COUNT           55 a           79 c           87 g           58 t
ORIGIN      
        1 acatggggtg tgcagtggta ccagcagacg ccaccgcagg cccctgtact ggtcatttat
       61 ggtgataggg aacggccctc agggatccct gagcgattct ctggctccaa ctcagggaac
      121 accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta ttactgtcag
      181 gtgtgggata gtagtagtaa atatgtgtta ttcggaggag ggacccggct gaccgtccta
      241 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004756             383 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:17281:17544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004756
VERSION     KCWK01004756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 383)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 383)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17281:17544"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..345
                     /note="immunoglobulin light chain variable region"
     V_region        3..345
     V_segment       3..308
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <273..>317
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70494.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       309..345
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        346..>383
                     /gene="IGLC"
BASE COUNT           78 a          124 c           98 g           83 t
ORIGIN      
        1 acatggggac tcagccggcc tccctctcag catctcctgg agcatcagcc agtctcacat
       61 gcaccttcag cggtggcatc aatgttgctg actaccacat acactggtac cagcagaagc
      121 cagggagtcc cccccggtat cttctgaggt acaaatcaga ctcagataag ggccagggct
      181 ctggagtccc cagccgcttc tctggatcca aagatgctgc agcgaacaca gggattttac
      241 gcatctctgg gctccagtct gaggatgagg ctgactatta ctgtgccatt gggcacagca
      301 gcggtcctta cttcttcggt gctgggaccc ggctcaccgt cctaggtcag cccaaggctt
      361 cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004757             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:6154:18808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004757
VERSION     KCWK01004757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6154:18808"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..432
                     /note="immunoglobulin light chain variable region"
     V_region        105..432
     V_segment       105..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70495.1"
                     /translation="DYYCSSYAGSKTLF"
     J_segment       401..432
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           88 a          156 c          123 g          103 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcagcgct ctcaggacgt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctccctc tgtgtctggg tctcctggac aggcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtgcttat aactatgtct cctggtacca gcagcaccca ggcaaagccc
      241 ccaaactcat gatttatgat gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaaatc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaaaacgtt attcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004758             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:9004:20525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004758
VERSION     KCWK01004758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9004:20525"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70496.1"
                     /translation="DYYCAAWDNSLSSPLF"
     J_segment       393..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          151 c          119 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcaggcaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 gttggaagta attatgtata ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atttatcata gtaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggataacag cctgagcagt ccgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004759             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:14247:13219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004759
VERSION     KCWK01004759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14247:13219"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..392
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70497.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           85 a          159 c          117 g          113 t
ORIGIN      
        1 acatggggct gggatctcag gaggcagcgc cctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaagc tgccccgact
      121 cagcctccct ctgtgtccgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgata ttgggtctta taatgctgtg tcttggtacc aacagcgtcc aggcaaagcc
      241 ccccaactca tagtttttga ggtcaataag cggccctcag gggtctctga tcgcttctct
      301 ggctccaact ctggcaacac ggcctccctg accatctctg ggctccaggc tgaggatgag
      361 gctgattatt actgctgctc atatgtaggc agcaacactt acatcttcga tgttgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004760             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:7159:21196
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004760
VERSION     KCWK01004760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:7159:21196"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70498.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          142 c          136 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccaccctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004761             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:19863:11188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004761
VERSION     KCWK01004761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:19863:11188"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..436
                     /note="immunoglobulin light chain variable region"
     V_region        108..436
     V_segment       108..402
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70499.1"
                     /translation="DYYCCSRSSSSTYVF"
     J_segment       403..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           82 a          162 c          119 g          113 t
ORIGIN      
        1 acatgggggg ctggggtctc agaaggcagc gctctcagga cgtctccacc atggcctgga
       61 ctctgctcct cgtcaccctc ctcactcaag gcacaggatc ctgggctcag tctgccccga
      121 ctcagcctcc ctctgtgtct gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga cgttggtggt tataactctg tctcctggta ccaacaacac ccaggcaaag
      241 cccccaaagt catgattttt ggtgtcaata atcggccctc tggggtctct gaccgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag tctgaggacg
      361 aggctgatta ttactgttgt tcacgttcaa gcagcagcac ttacgtcttc ggtcctggga
      421 cccggctcac cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004762             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:10044:17532
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004762
VERSION     KCWK01004762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10044:17532"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..232
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <188..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70500.1"
                     /translation="DYHCAAGYGSGSSWQWVF"
     J_segment       233..269
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           66 a           89 c           96 g           56 t
ORIGIN      
        1 acatggggga aatgaattgg ggaatgtata cgcctactgg caccagcaga agccaggcca
       61 ggcccctgta ttggtcatct acaaagataa gaaccggccc tcagggatcc ctgagcgatt
      121 ctctggctcc agctcaggga acacggccac cctgaccatc agtagggtcg aggctgggga
      181 tgaggccgac tatcactgtg ctgcaggcta tggcagtggg agcagctggc agtgggtatt
      241 cggcggaggg acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01004763             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:22389:11342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004763
VERSION     KCWK01004763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22389:11342"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70501.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          161 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggt tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004764             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:17417:13575
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004764
VERSION     KCWK01004764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17417:13575"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70502.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          148 c          129 g           97 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttgggagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gtactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcggcg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004765             276 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15572:19223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004765
VERSION     KCWK01004765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 276)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 276)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..276
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15572:19223"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..236
                     /note="immunoglobulin light chain variable region"
     V_region        8..236
     V_segment       8..201
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <166..>210
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70503.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       202..236
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        237..>276
                     /gene="IGLC"
BASE COUNT           54 a           88 c           67 g           67 t
ORIGIN      
        1 acatgggaga agccagggag tcctccccgg taccttctct actactactc agactcaagt
       61 aaacaccagg gctctggagt ccccagccgc ttctctggat ccaaagatgc ttcggccaat
      121 gcaggccttt tactgatctc tggggtccag tctgaagatg aggctgacta ttactgtgcc
      181 atatggcaca gtagcgcttc ttacttcttc ggtactggga cccggctcac cgtcctgggt
      241 cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004766             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13342:4975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004766
VERSION     KCWK01004766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13342:4975"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70504.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          149 c          122 g          107 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgta
       61 ctcaccctcc tcactcactg tgcagggtcc tgggctcagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctctt gttctggaag catctccagc
      181 attggaagta gtgatgtatg ttggtaccag caactcccag gaacggcccc caaactcctc
      241 atcaattata gtgatcagcg actctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcct gggatagcag cctgagcagt ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004767             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:17903:20364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004767
VERSION     KCWK01004767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17903:20364"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70505.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          164 c          123 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggtcctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004768             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:9833:9468
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004768
VERSION     KCWK01004768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9833:9468"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70506.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       399..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           95 a          152 c          115 g          110 t
ORIGIN      
        1 acatggggct ctggagccag ggatcccttc caatatcagc accatggcct ggactctgct
       61 cctcctccag ttcctcctca cttgctgccc agggtccaat tctcaggctg tagtgactca
      121 ggagccctca atgactgtgt ccccaggagg gacagtcact ctcacctgtg cttccagcac
      181 tggagcagtc accagtggtc actctccaca ctggttccag cagaaacctg gacaagcccc
      241 caagacactg atttataata caaactacag acactcctgg actcctgccc ggttctcagg
      301 ctccctcctt gggggtaaag ctgccctgac actgtcaggt gcgcagcctg aggatgaggc
      361 tgagtattat tgtttactat actatagtgg tgctcagctg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004769             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:17643:6967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004769
VERSION     KCWK01004769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:17643:6967"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70507.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           97 a          141 c          131 g           91 t
ORIGIN      
        1 atggggctgg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgagc tgactcaggc
      121 accctcagtg tcagcggcct caggacagac ggccaggatc acctgtggcg gagacaacat
      181 tggaattaaa aatgtccact ggtaccagca gaagccagca caggcccctg tggtagtcat
      241 ctatgctgat aacaaacggc cctcagggat ccctgagcga ctctctggct ccaactcagg
      301 gaatattgcc accctgacca tcagcagggt cgaggccggg gatgaggcag actattactg
      361 tcaggtgtgg gacagtagta gtaaatgggt attcggcgga gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004770             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:12909:3819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004770
VERSION     KCWK01004770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12909:3819"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70508.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          155 c          121 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacgggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004771             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:12082:4893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004771
VERSION     KCWK01004771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12082:4893"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70509.1"
                     /translation="DYYCQSYDSSLSGVLF"
     J_segment       408..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           89 a          153 c          127 g          111 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcagt
      181 gggagcaact ccaacattgg atactattat gtgcagtggt accagcagct tccagggacg
      241 gcccccaaac tcctcatcta tgaaaataat aagcgaccct ctggggtttc tgatcgattc
      301 tctggctccc agtctggtac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagtttga gtggtgtctt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004772             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:20583:10477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004772
VERSION     KCWK01004772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20583:10477"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70510.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          151 c          122 g          112 t
ORIGIN      
        1 acatgggggc ttggatctca ggaggaagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatggagg cagcaatagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004773             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:22463:14288
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004773
VERSION     KCWK01004773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:22463:14288"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70511.1"
                     /translation="DYYCAAWDDRLTGYVF"
     J_segment       415..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          158 c          125 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cgggagcaat agtgtatcct ggtaccagct gctcccagaa
      241 acggctccca aactcctcat ctattataat aatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatcgcc tgaccggtta cgtattcggt
      421 gttgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004774             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:14143:15661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004774
VERSION     KCWK01004774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14143:15661"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70512.1"
                     /translation="DYFCAIGHSSGDYIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>479
                     /gene="IGLC"
BASE COUNT           92 a          158 c          119 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaaaccttt gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccatctacag tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcagactca gatcagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattgggc acagcagcgg tgattacata ttcggtgccg
      421 ggacccggct caccgtccca ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004775             393 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10595:11284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004775
VERSION     KCWK01004775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 393)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10595:11284"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    77..355
                     /note="immunoglobulin light chain variable region"
     V_region        77..355
     V_segment       77..316
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <280..>327
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70513.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       318..355
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        356..>393
                     /gene="IGLC"
BASE COUNT           78 a          123 c           98 g           94 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac cctctcctgc actgggagca gctccaacat tggagattat
      121 tatgtgcagt ggtaccagca gcttccagga acggccccca aactcctcat ctatgaaaat
      181 aataagcgac cctcaggggt ttctgatcga ttctctggct cccagtctgg tacctcagcc
      241 tccctgacca tcactggact ccagtctgac gatgaggctg attattactg tcagtcctat
      301 gatagcagcc tgagtgttgt gttattcgga ggagggaccc ggctgaccgt cctaggtcag
      361 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004776             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:14038:7750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004776
VERSION     KCWK01004776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14038:7750"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70514.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          141 c          135 g           99 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccagcctcgg tgtcagtgtc cccgggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta aaaatgtgca ctggtaccag caggagccac cgcaggcccc tgtgttggtc
      241 atcttttatg ataacaaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacatcg ccaccctgac catcagcgag gccgaggccg gggatgaggc tgactattac
      361 tgtcagctgt gggacagtag tgttgatcat ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004777             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:10145:17572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004777
VERSION     KCWK01004777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10145:17572"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    77..401
                     /note="immunoglobulin light chain variable region"
     V_region        77..401
     V_segment       77..362
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <326..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70515.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       367..401
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>439
                     /gene="IGLC"
BASE COUNT          101 a          133 c          111 g           94 t
ORIGIN      
        1 acatgggggg tgtctcacca tgacctggac cactgttctg ctcccctttc tcactctctg
       61 cacaggctct gaggcctcct atgagctgac acagccaccc tcagtgtcag tgtccccagg
      121 acagacggcc aggatcacct gctctggaga aatactggca aaaaaatata ctcagtggtt
      181 ccagcagcag ccaggccagg cccctttcct ggtgatatat aaagacagtg agaggccctc
      241 agggatccct gagcgattct ctagctccag ttcagggaca acaattacct tgaccatcag
      301 tggggcccag gcagaagatg aggctgacta ttactgtcaa tcagtagaca gcagtggaaa
      361 tcttccgtta ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc
      421 ctcggtcact ctcttcccg
//
LOCUS       KCWK01004778             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:21156:17811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004778
VERSION     KCWK01004778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:21156:17811"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..314
                     /note="immunoglobulin light chain variable region"
     V_region        7..314
     V_segment       7..277
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70516.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       278..314
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           76 a          105 c           92 g           79 t
ORIGIN      
        1 acatggggga gcatcggcca gactcccctg caccctgagc agtgacctca gtgttggtgg
       61 taaaaacatg tactggtacc agcagaagcc agggcgcgct cccaggtttt tcctgtacta
      121 caactccgac tcagacaagc agctgggacc tggggtcccc aatcgagtct ctggctccaa
      181 ggagacctca actaacacag cgtttttgct catctctggg ctccagcctg aggacgaggc
      241 cgattattac tgtcatgtat atgacagtag tactaatgtg ttattcggag gagggacccg
      301 tctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004779             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:9622:4830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004779
VERSION     KCWK01004779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:9622:4830"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70517.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          155 c          117 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctgtgct gactcagccg gcctccctct
      121 cagcatctcc tggaacatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catatactgg taccaccaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacacatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacaca gcagcggtga ttatatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004780             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:12694:8595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004780
VERSION     KCWK01004780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12694:8595"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    57..405
                     /note="immunoglobulin light chain variable region"
     V_region        57..405
     V_segment       57..368
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70518.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       369..405
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>443
                     /gene="IGLC"
BASE COUNT           85 a          153 c           97 g          108 t
ORIGIN      
        1 acatggggac tcctctcctc ctcctgctcc tctctcactg cacaggttcc ctctcccagc
       61 ctgtactgac ccagccaacc tccctctcag catctccggg agcatcagcc agactcagct
      121 gcaccttgag cagtggcatc aatgttggta gttacagcgt attctggtac cagcagaagc
      181 cagggagtcc tccccggttc cttctgtact actactcaga ctcaagtaaa caccagggct
      241 ctggagtccc cagccgcttc tctggatcca aagatgcttc ggccaatgca ggccttttac
      301 tgatctctag gctccagtct gaagatgagg ctgactatta ctgtgccata tggcacagca
      361 gcgcttctta cttcttcggt actgggaccc ggctcaccgt cctaggtcag cccaaggctt
      421 cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004781             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:22248:13896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004781
VERSION     KCWK01004781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22248:13896"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..437
                     /note="immunoglobulin light chain variable region"
     V_region        92..437
     V_segment       92..400
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70519.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       401..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           93 a          160 c          111 g          111 t
ORIGIN      
        1 acatgggact gcagggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc ccagcctgtg ctgacccagc caacctccct
      121 ctcagcatct ccgggagcat cagccagact cagctgcacc ttgagcagtg gcaatgttgg
      181 tagttacagc atattctggt accagcagaa gccagggagt cctccccggt accttcttta
      241 ctactactca gactcaagta accaccagga ctctggagtc cccagccgct tctctggatc
      301 gaaagatgct tcagccaatg cagggctttt actgatctct gggctccagt ctgaagatga
      361 ggctgactat tactgtgcca catggcacag cagcgcttct tacatcttcg gtggtgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004782             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:17576:11920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004782
VERSION     KCWK01004782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17576:11920"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..441
                     /note="immunoglobulin light chain variable region"
     V_region        95..441
     V_segment       95..406
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70520.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>481
                     /gene="IGLC"
BASE COUNT           92 a          164 c          111 g          114 t
ORIGIN      
        1 acatggggcc actgcaggga aagaggctgt gtccaccatg gcctggactc ctctcctcct
       61 cctgctcctc tctcactgca caggttccct ctcccagcct gtgctgaccc agccaacctc
      121 cctctcagca tctccgggag catcagccag actcagctgc acctttagca gtggcatcaa
      181 tgttggtagt tacagcatat tctggtacca gcagaagcca gggagtcctc cccggtacct
      241 tctctactac tactcagact caagtaaaca ccagggctct ggagtcccca gccgcttctc
      301 tggatccaaa gatgcttcgg ccaatgcagg ccttttactg atctctgggc tccagtctga
      361 agatgaggct gactattact gtgccatatg gcacagcagc gcttcttact tcttcggtag
      421 tgggacccgg ctcaccgtcc tgggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01004783             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20615:9470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004783
VERSION     KCWK01004783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20615:9470"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70521.1"
                     /translation="DYYCQSYGSSLSVVLF"
     J_segment       406..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           88 a          153 c          129 g          111 t
ORIGIN      
        1 acatgggggg cttcagctgt gggcacagga agcagcactc aggacagtct ccagcatggc
       61 ctggtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag tgtctggggc gcccgggcag agggtcacca tctcctgcac
      181 tgggagcagc tccaacattg gaggttatta tgtgcagtgg taccagcagc ttccaggagc
      241 ggcccccaaa ctcctcatct atgaaaatga taaacgaccc tcaggggttt ctgatcgatt
      301 ctctggctcc cagtctgatt cctcagcctc cctgaccatc actggactcc agtctgagga
      361 tgaggctgat tattactgcc agtcctatgg cagcagcttg agtgttgtgt tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01004784             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:25820:19513
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004784
VERSION     KCWK01004784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25820:19513"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..432
                     /note="immunoglobulin light chain variable region"
     V_region        99..432
     V_segment       99..395
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70522.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       396..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           83 a          164 c          122 g          101 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct gaccccaatc ctcctcctcc
       61 tcctcactct cctccttcac tgcacagggt ctctctccca gcctgtgctg actcagtcgc
      121 cctctgcctc tgcctccctg ggagcctcgg tcaagctcac ctgcactctg agcagtggcc
      181 actacagcta caccatcgca tggcatcagc agcagcaagg gaaggcccct cggttcttga
      241 tgtggcttaa gagtgatggc agccacacca agggggacgg ggtccctgat cgcttctcag
      301 gctccagctc cggggctgag cgctacctca ccatctccaa cctccagtct gaggatgagg
      361 ctgattatta ctgtcagacc tgggatattg gcatttgggt attcggcgga gggacccggc
      421 taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004785             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:19553:10773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004785
VERSION     KCWK01004785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19553:10773"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..389
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70523.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           89 a          152 c          121 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgcct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 actccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgatattg ggtattatca tgctgtgtct tggtaccagc atcatccagg caaagccccc
      241 aaactcatga tttatgaggt caataaacgg cccgcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 gattattact gtagctcata tgcaggcagc aacagtttat tcttcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004786             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:13721:4396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004786
VERSION     KCWK01004786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13721:4396"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..389
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70524.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       390..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           98 a          142 c          132 g           91 t
ORIGIN      
        1 acatgggggc tgggtctcag gaggcagcat tgacggtgcc tcagccatgg cctggaccct
       61 tctcctcctc ggcctcctcg cttactgcac aggctctgcg acctcctatg agctgactca
      121 ggcaccctca gtgtcagcgg cctcaggaca gacggccagg atcacctgtg gcggagacaa
      181 cattggaatt aaaaatgtcc actggtacca gcagaagcca gcacaggccc ctgtggtagt
      241 catctatgct gataacaaac ggccctcagg gatccctgag cgactctctg gctccaactc
      301 agggaatatt gccaccctga ccatcagcag ggtcgaggcc ggggatgagg cagactatta
      361 ctgtcaggtg tgggacagta gtagtaaatg ggtattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004787             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:22652:18054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004787
VERSION     KCWK01004787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22652:18054"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..407
                     /note="immunoglobulin light chain variable region"
     V_region        87..407
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70525.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       372..407
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>446
                     /gene="IGLC"
BASE COUNT           93 a          141 c          115 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aagatcacct gctctggaga tgcactgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcgat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gcagtggtta tggcttattc ggaggaagga cccggctgac cgtcctacgt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004788             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:24814:14768
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004788
VERSION     KCWK01004788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:24814:14768"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70526.1"
                     /translation="DCHCCSSWGGNTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           79 a          156 c          129 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac agaaccctgg gctcagtctg ccctgactca
      121 gcctccctca gtgcccaggt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 aagtgacatt ggtggttgta atggcgtctc ctggtaccag caacattcag ggacagcccc
      241 cagactcctg ctttatgatg tcagtaagcg gccctcaggg gtctctgatt gcttctctgg
      301 ttccaagtct ggcatcacgg cctccctgac catctctggg ctccaggctg aagacaagac
      361 tgattgtcac tgctgctcat cttggggtgg aaacacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctgggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004789             364 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:14962:7794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004789
VERSION     KCWK01004789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 364)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14962:7794"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..326
                     /note="immunoglobulin light chain variable region"
     V_region        8..326
     V_segment       8..289
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <251..>298
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70527.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       290..326
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        327..>364
                     /gene="IGLC"
BASE COUNT           77 a          112 c          102 g           73 t
ORIGIN      
        1 acatggggat ctgactcagc caccctcggt gtcagtgtcc ccaggacaga cggccaggat
       61 cacctgtggg ggagacaaca ttggaagtaa gagtgtgcac tggtaccaac acaagccacc
      121 gcaggcccct atcctggtca tctattatta taccgaacgg ccctcggcga tccctgagcg
      181 attctctggc tccaaatcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      241 ggatgaggct gactattact gtcaggtgtg ggacactact attgatcatg gctttttcgg
      301 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      361 cccg
//
LOCUS       KCWK01004790             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:13752:14141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004790
VERSION     KCWK01004790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13752:14141"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70528.1"
                     /translation="DYSCCSYRSGNTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           81 a          157 c          128 g          107 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcagcgct ctcgggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcagtct gccctgactc
      121 agcctccctc agtgtccaag tctcttggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat tggtggttat gatggcgtct cctggtacca gcagcactca gggacagccc
      241 ccagactcct gatttatgat gtcactaagc ggccctcagg ggtctcggat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctca ccatctctgg gctccagact gaggacgagg
      361 ctgattattc ttgttgctca tataggagtg gaaacacttg gctattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004791             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:27833:17564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004791
VERSION     KCWK01004791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:27833:17564"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..270
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70529.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       271..306
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           78 a          103 c           98 g           65 t
ORIGIN      
        1 acatgggctc agtgtcagcg gcctcaggac agacggccag gatcacctgt ggcggagaca
       61 acattggaat taaaaatgta cactggtacc accagaagcc accgcaggcc cctgtgctgg
      121 tcatctttgc tgataacaaa cggccctcag ggatccctga gcgattctct gcctccaact
      181 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      241 actgtcaggt gtgggacagt agtagtaaat gggtattcgg cggagggacc cggctaaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004792             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:6291:12880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004792
VERSION     KCWK01004792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6291:12880"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70530.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          140 c          136 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaggccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004793             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15871:4820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004793
VERSION     KCWK01004793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15871:4820"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70531.1"
                     /translation="DYYCHSADGDYRIF"
     J_segment       405..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           84 a          161 c          127 g          103 t
ORIGIN      
        1 acatggggct ggctgtgact cagaaagcag agcctggggc gtctccacca tggcctgggc
       61 tccactcctc ctcaccctcc tcgctcactg cacagggtct tgggctgagg ttgtgttcac
      121 tcagccccat tctgtgtcgg ggtctccggg gcagacggtc accatctcct gcacccgcag
      181 cagtggcagc attgattatg aatatgtgca gtggtaccag cagcgcccgg gcagtgcccc
      241 caccacagtg atttacaaag atgaccaaag accctctggg gtccctgatc ggttctctgg
      301 ctccatcgac agctcctcca actctgcctc cctcgccatc tctgggctaa agtctgagga
      361 cgaggctgac tactactgtc actctgctga tggcgactac aggatattcg gcggagggac
      421 ccggctcacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004794             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:28176:9744
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004794
VERSION     KCWK01004794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:28176:9744"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70532.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaatggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004795             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:19614:12161
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004795
VERSION     KCWK01004795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:19614:12161"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70533.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           85 a          155 c          122 g          107 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtctccatc tcctgttctg gaagcagctc
      181 caacatcgga agtcatagtg tctcctggta ccagcagctc ccaggcacag ctcccaaact
      241 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctctca
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcttgggatg atagcctgag cggttacatc ttcggtgctg ggacccggct
      421 cgccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004796             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:28913:17693
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004796
VERSION     KCWK01004796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:28913:17693"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70534.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>459
                     /gene="IGLC"
BASE COUNT           88 a          142 c          127 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gaggtgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004797             339 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:21648:18234
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004797
VERSION     KCWK01004797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 339)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21648:18234"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..300
                     /note="immunoglobulin light chain variable region"
     V_region        10..300
     V_segment       10..263
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <226..>273
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70535.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       265..300
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        301..>339
                     /gene="IGLC"
BASE COUNT           75 a          102 c           96 g           66 t
ORIGIN      
        1 acatgggcag tgtccccagg acagacggcc aggatcacct gtgggggaga caacattgga
       61 agtcaaagtg tgcactggta ccagcacaag ccaccgcagg cccctgttct ggtcatcttt
      121 tattataccg aacggccctc aggaatccct gagcgaatct ctggctccaa atcagggaac
      181 accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta ttactgtcag
      241 gtgtgggaca caagtcttga tcacggctta tttggaggag ggacccggct gaccgtccta
      301 agtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004798             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:19493:8891
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004798
VERSION     KCWK01004798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19493:8891"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..390
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70536.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       392..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          151 c          121 g          107 t
ORIGIN      
        1 acatgggggc acaggaggca gcactcagga cagtctccag catggcctgg tctcctctcc
       61 tcctcaccct tctcattcac tgcacagggt cctgggccca gtctgtgctg acgcagccgc
      121 cctcagtgtc tggggcgccc gggcagaggg tcaccctctc ctgcactggg agcagctcca
      181 acattggaga ttattatgtg cagtggtacc agcagcttcc aggaacggcc cccaaactcc
      241 tcatctatga aaataataag cgaccctcag gggtttctga tcgattctct ggctcccagt
      301 ctggtacctc agcctccctg accatcactg gactccagtc tgacgatgag gctgattatt
      361 actgtcagtc ctatgatagc agcctgagtg ttgtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004799             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:8130:7705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004799
VERSION     KCWK01004799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8130:7705"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70537.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          150 c          117 g          107 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc cggcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004800             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:10007:20396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004800
VERSION     KCWK01004800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:10007:20396"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70538.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       411..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           86 a          158 c          128 g          111 t
ORIGIN      
        1 acatgggggc tcattcctgg ctgtggctca ggaagcagag cctggagcat ctccaccatg
       61 gcctgggctc cactcctcct caccctcctc gctcactgca cagggtcttg ggctgaggtt
      121 gtgttcactc agccccaatc tgtgtcgggg tctccgggac agacggtcac catctcctgc
      181 acccgcagca gtggcagcat tggcaacagc tatgtgtact ggttcaagaa gcggccgggc
      241 agcgtcccca ctattgtgat ttacaaagat gaccaaagac cctctggggt ccctgatcgg
      301 ttctctggct ccatcgacag ctcctccaac tctgcctccc tcaccatctc tggactgaag
      361 tctggggacg aggctgacta ttactgtcag tcttttgaca gcagcagtgt cttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004801             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:6665:5461
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004801
VERSION     KCWK01004801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6665:5461"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70539.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       414..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          156 c          123 g          111 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccggaca gagggtcacc atttcctgca
      181 ttagcagcag ctccaacatc ggggcggctt attatgtatc ctggtaccaa cagttcccag
      241 gaacagcccc caaactcctc atctttgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtccctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattac tgtttagcat gggataccag cctgaattgg atcttcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004802             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:24295:4729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004802
VERSION     KCWK01004802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24295:4729"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70540.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          160 c          119 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ccctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcatcatgg gatgataccc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004803             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:8503:10636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004803
VERSION     KCWK01004803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:8503:10636"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70541.1"
                     /translation="DYHCQVWDINSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          141 c          137 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagt ctctgcggcc tcctatgatc tgacgcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccaggctg acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgac agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgagca tcagcggggt cgaggccggg gatgaggctg actatcactg
      361 tcaggtgtgg gacattaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004804             272 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:6736:20860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004804
VERSION     KCWK01004804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 272)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 272)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..272
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:6736:20860"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..234
                     /note="immunoglobulin light chain variable region"
     V_region        8..234
     V_segment       8..198
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <162..>206
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70542.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       202..234
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        235..>272
                     /gene="IGLC"
BASE COUNT           56 a           81 c           81 g           54 t
ORIGIN      
        1 acatggggca ctggtaccaa cagaagccac cgcagggccc tctattggtc atctttgctg
       61 atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca gggaacaccg
      121 ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac tgtcaggtgt
      181 gggacagtag tagtaaatgg atattcggcg gggggacccg gctaagcgtc ctaggtcagc
      241 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004805             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:18573:15060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004805
VERSION     KCWK01004805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18573:15060"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70543.1"
                     /translation="DYSCAIGHSSGPYIF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           97 a          161 c          110 g          106 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcaactcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 gactaccaca tacactggta ccagcagaag ccagggagtc ccccccggta tcttctgagt
      241 tacaaatcag actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaaaatactt caacgaacac aggcatttta cacatctctg ggctccagtc tgaggatgag
      361 gctgactatt cctgtgccat tggacacagc agcggtcctt acatcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004806             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:22197:17850
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004806
VERSION     KCWK01004806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:22197:17850"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70544.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           82 a          164 c          124 g          101 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggc
      181 cactacagct acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggttcttg
      241 atgtggctta agagtgatgg cagccacacc aagggggacg gggtccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatatt ggcatttggg tattcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc cagggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004807             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:16149:5269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004807
VERSION     KCWK01004807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16149:5269"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70545.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          153 c          114 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcaacgtctg aggccgccag gaagagtgtc accatctcct gttctggaag caactccaac
      181 atcggaagtt ataatgtgtc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata atgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagcggt tacatcttcg ctgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004808             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:16926:10856
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004808
VERSION     KCWK01004808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16926:10856"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70546.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          152 c          122 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgaa ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004809             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:10416:17853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004809
VERSION     KCWK01004809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10416:17853"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..279
                     /note="immunoglobulin light chain variable region"
     V_region        4..279
     V_segment       4..240
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <210..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70547.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       242..279
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>317
                     /gene="IGLC"
BASE COUNT           66 a           92 c           85 g           74 t
ORIGIN      
        1 acatgggcag tgacctcagt gttggtagta aaaacatgta ctggtaccag cagaagccag
       61 ggagcgctcc caggttattc ctgtactact actccgactc agacaaccag ctgggacctg
      121 gggtccccaa tcgagtctct ggctccaagg agacctcaag taacacagcg tttttgctca
      181 tctctgggct ccagcctgag gacgaggccg attatttctg ccaggtgttt gacagtagtg
      241 ttgtgttctt cggaggaggg acccgactga ccgtcctagg tcagcccaag gctgccccct
      301 cggtcactct cttcccg
//
LOCUS       KCWK01004810             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:19351:10071
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004810
VERSION     KCWK01004810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19351:10071"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70548.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          137 c          121 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac agtctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004811             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:14679:11832
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004811
VERSION     KCWK01004811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14679:11832"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70549.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          162 c          119 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc tctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004812             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:23299:13716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004812
VERSION     KCWK01004812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:23299:13716"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70550.1"
                     /translation="DYFCQVFDSSVMFF"
     J_segment       409..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttatg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004813             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:8730:9020
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004813
VERSION     KCWK01004813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8730:9020"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70551.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       393..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          154 c          121 g          106 t
ORIGIN      
        1 acatgggggt acagaaggca ggactcagga caatctccag catggcctgg ttccctctcg
       61 tcctcaccct cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagcctc
      121 cctcagcgtc tgaggccgcc gggaagagtg tctccatctc ctgttctgga agcagctcca
      181 acatcggaag tcatagtgtc tcctggtacc agcagctccc aggaacagct cccaaactcc
      241 tcatctatta tagtgatcaa cgagcctcag gtgtctctga ccgattctct ggctctcagt
      301 ctggcacgtc agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt
      361 actgcgcagc atgggatgat agcctgagcg gttacatctt cggtgctggg acccggctcg
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01004814             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:12185:13251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004814
VERSION     KCWK01004814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:12185:13251"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70552.1"
                     /translation="DYYCQVWDSSSEWVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          142 c          135 g           91 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacaga ctctgcgacc tcctatgaat tgactcaggc
      121 accctcagtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaaa actgtgcact ggtaccaaca gaaggcagcg caggcccctg tgctggtcat
      241 ctttgctgat agcaaacggc cctcagggat ccctgaccga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtgaatgggt tttcggcgga gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004815             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:5650:14828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004815
VERSION     KCWK01004815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5650:14828"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70553.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           96 a          159 c          121 g          108 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aagagtgtca ccatctcctg
      181 ttctggaagc acctccaaca tcggaagcaa taatgtatcc tggtaccagc agctcccagg
      241 aacagctccc aaactcctct tttattataa tgatcaacga gcctcaggtg tctctgaccg
      301 attctcttgc tccaagtctg gcacgtcagc ctccccggcc atcagtgggc tccagaccga
      361 ggatgaggct gattattact gcgcagcatg ggatgataac ctgagcggct acatcttcgg
      421 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01004816             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:15678:11332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004816
VERSION     KCWK01004816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15678:11332"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70554.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           96 a          152 c          116 g          112 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt caacggtggc atcactgttg
      181 ctggctacca tatatattgg taccaacaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatatc tggactccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacaca gcagcggtga ttatatcttc ggtggtggga
      421 cccgtctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004817             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:9090:13624
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004817
VERSION     KCWK01004817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9090:13624"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70555.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          144 c          134 g          102 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtcaa ctggtaccaa cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgacc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgcggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tactgatcat ccggtgttgt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004818             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:18880:5201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004818
VERSION     KCWK01004818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18880:5201"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70556.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          148 c          130 g           98 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt caaagtgtac actggtacca gcacaagcca ccgcaggccc ctgttctggt
      241 catcttttat tataccgaac ggccctcagg aatccctgag cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacacaa ctattgatca cggcttgttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004819             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:8813:18284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004819
VERSION     KCWK01004819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:8813:18284"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70557.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       412..448
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           96 a          157 c          124 g          109 t
ORIGIN      
        1 acatggggag cgcagcttca gctgtgggta cagaaggcag gactcaggac aatctccagc
       61 atggcctggt tccctctcgt cctcaccctc ctcactcact gtgcagggtc ctgggcccag
      121 tctgtgctga ctcagcctcc ctcagcgtct gaggccgcca ggaagagtgt caccatctcc
      181 tgttctggaa gcagctccaa catcggaagt aataatgtgt cctggtacca gcacctccca
      241 ggaacagctc ccaaactcct catctattat aatgatcaac gaggctcagg tgtctctgac
      301 cgattctctg gctccaagtc tggcacgtca gcctccctgg ccattagtgg gctccagacc
      361 gaggatgagg ctgattatta ctgcgcagcg tgggatgata gcctgagcag ttacatcttc
      421 gctgctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      481 ttcccg
//
LOCUS       KCWK01004820             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:15869:2292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004820
VERSION     KCWK01004820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15869:2292"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..258
                     /note="immunoglobulin light chain variable region"
     V_region        8..258
     V_segment       8..218
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <183..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70558.1"
                     /translation="DYYCSSYAGSNTHWLF"
     J_segment       228..258
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           62 a           94 c           71 g           69 t
ORIGIN      
        1 acatgggcat cggtggttat aactatgtct cctggtacca gctacaccca ggcaaagccc
       61 ccaaactcat gatttatgat gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      121 gctccaaatc tgacaacacg gcctccctga ccatctctgg gctccaggct gaggatgaga
      181 ctgattatta ctgcagctca tatgcaggca gcaacactca ttggcttttc ggcggaggga
      241 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004821             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:16386:5211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004821
VERSION     KCWK01004821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16386:5211"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70559.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       407..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          151 c          129 g          114 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgttgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgca
      181 ctgggagcag gtccaacatc ggggcgggtt tttatttttc ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctttgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattat tgttcatcat gggaaagcag cctgaattgg gtattcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004822             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:14681:20702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004822
VERSION     KCWK01004822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:14681:20702"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..266
                     /note="immunoglobulin light chain variable region"
     V_region        8..266
     V_segment       8..229
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70560.1"
                     /translation="DYYCQVWDSSSDHWIF"
     J_segment       230..266
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           66 a           88 c           92 g           58 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaagtaa atatgtgcac tggtaccagc agaggccacc
       61 gcaggcccct gtgcaagtca tctatactga tagcagacgg ccctcaggga tccctgagcg
      121 attctctggc tccaactcag ggaacaccgc caccctgacc atcagcgcgg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggacagtagt agtgatcatt ggatattcgg
      241 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      301 cccg
//
LOCUS       KCWK01004823             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:11755:12791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004823
VERSION     KCWK01004823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11755:12791"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..230
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <197..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70561.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       235..269
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           61 a           94 c           76 g           76 t
ORIGIN      
        1 acatggggtt ggttcttaca ccatattctg gtaccagcag aagccaggga gtcctccccg
       61 gttccttctg tactactact cagactcaaa taatcaccag ggctctggag tccccagccg
      121 cttctctgga tccaaagatg cttcagccaa tgcagggctt ttactgatct ctgggctcca
      181 gtctgaagat gaggctgact attactgtgc catgtggcac agcagcgctt atgccttatt
      241 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01004824             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:10953:20739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004824
VERSION     KCWK01004824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10953:20739"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..394
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70562.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       408..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           88 a          155 c          123 g          110 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc gctctcagga cttctccagc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccccga
      121 ctcagactcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tattgggtat tatcatgctg tgtcttggta ccagcatcat ccaggcaaag
      241 cccccaaact catgatttat gaggtcaata aacggcccgc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag actgaggatg
      361 aggctgatta ttactgcagc tcatatgcag gcagcaacgc tttattcttc ggaggaggga
      421 cccgcctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004825             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:9980:12780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004825
VERSION     KCWK01004825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9980:12780"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..263
                     /note="immunoglobulin light chain variable region"
     V_region        4..263
     V_segment       4..225
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <188..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70563.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       227..263
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           67 a           90 c           83 g           61 t
ORIGIN      
        1 acatggggga gacaacattg gaagtcaaag tgtgcactgg taccagcaca agccaccgca
       61 ggcccctgta ctggtcatct tttattatac cgaacggccc tcaggaatcc ctgagcgatt
      121 ctctggctcc aaatcaggga ataccgccac cctgaccatc agcggggtcg aggccgggga
      181 tgaggctgac tattactgtc aggtgtggga cacaactatt gatcacggct tattcggagg
      241 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01004826             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:21279:3957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004826
VERSION     KCWK01004826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21279:3957"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70564.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          157 c          119 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagtcagg gagtcctccc cggtatcttc
      241 taagatacaa atcagactca gatcagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaagga tgcttcagcg aacacgggga ttttacacgt ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004827             295 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:9270:7140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004827
VERSION     KCWK01004827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 295)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9270:7140"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..257
                     /note="immunoglobulin light chain variable region"
     V_region        8..257
     V_segment       8..225
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>229
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70565.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       226..257
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>295
                     /gene="IGLC"
BASE COUNT           67 a           89 c           81 g           58 t
ORIGIN      
        1 acatggggga gacagcctca gaagttatta tgcaagttgg taccagcaga agccaggcca
       61 ggcccctata ctggtcgtct atggtaacaa ttaccggccc tcagggatcc cagagcgatt
      121 ctctggctcc agtacacgaa acacagcttc cttgaccatc actggggctc aggtggaaga
      181 tgaggctgac tattactgtg actcctggga cagccgcgga acccaattcg gaggagggac
      241 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004828             372 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:21965:6896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004828
VERSION     KCWK01004828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 372)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21965:6896"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..334
                     /note="immunoglobulin light chain variable region"
     V_region        115..334
     V_segment       115..297
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>306
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70566.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       298..334
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        335..>372
                     /gene="IGLC"
BASE COUNT           66 a          124 c           93 g           89 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagcgct
      121 cccaggtcat tcctatacta ctactccgac tcagacaagc agctgggacc tggggtcccc
      181 aatcgagtct ctggctccaa ggagacctca agtaacacag cgtttttgct catctctgga
      241 ctccagcctg aggacgaggc cgattattac tgtcaggtgt atgacagtag tgctaatgtg
      301 ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      361 actctcttcc cg
//
LOCUS       KCWK01004829             373 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:24942:13902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004829
VERSION     KCWK01004829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 373)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:24942:13902"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..335
                     /note="immunoglobulin light chain variable region"
     V_region        7..335
     V_segment       7..295
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <263..>307
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70567.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       298..335
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        336..>373
                     /gene="IGLC"
BASE COUNT           77 a          115 c           96 g           85 t
ORIGIN      
        1 acatggggcc tccctctcag catctcctgg aacatcagcc agtctcacat gcaccttcag
       61 cggtggcatc aatgttgttg gctaccacat acactggtac cagcagaagc cagggagtcc
      121 tccccggtat cttctgagat acaaatcgga ctcagataag ggccagggct ctggagtccc
      181 cagccgcttc tctggatcca aagatgcttc agtgaacgca gggattttac gcatctctgg
      241 gctccagtct gaggatgagg ctgactatta ctgtgccatt gggcacagca gcggtgatta
      301 catcttcggt gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt
      361 cactctgttc ccg
//
LOCUS       KCWK01004830             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:21295:14781
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004830
VERSION     KCWK01004830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:21295:14781"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70568.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          154 c          111 g          117 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttggtaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcatc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggca ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004831             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:19388:7577
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004831
VERSION     KCWK01004831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19388:7577"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    77..398
                     /note="immunoglobulin light chain variable region"
     V_region        77..398
     V_segment       77..361
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <326..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70569.1"
                     /translation="DYYCYSADNSGHGFF"
     J_segment       362..398
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>436
                     /gene="IGLC"
BASE COUNT           86 a          138 c          114 g           98 t
ORIGIN      
        1 acatgggggg tgtctcacca tggcctggat tcctctccta ctccccatcc tcactttctg
       61 cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag tgtccccagg
      121 acagccggcc aggatcacct gctctggaga tgtattgcca aaaaaatatg cttattggtt
      181 ccagcagaag ccaggccagt cccctgtatt ggtcatctct gaggacaccg aacggccctc
      241 tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct tgactatcag
      301 tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca atagtggtca
      361 tggcttcttc ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      421 ggtcactctc ttcccg
//
LOCUS       KCWK01004832             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:17976:14999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004832
VERSION     KCWK01004832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17976:14999"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70570.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       392..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>464
                     /gene="IGLC"
BASE COUNT           89 a          144 c          136 g           95 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag actctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaggtga agttgtgaac tggtaccagc agaagccacc gcaggcccct gtcctggtca
      241 tctatgctaa taacgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg gggcgttact agtgatcatc ccttattcgg aggagggacc cggctgaccg
      421 tccaaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004833             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:28392:7980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004833
VERSION     KCWK01004833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:28392:7980"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70571.1"
                     /translation="DYYCQSADSDGNHPLF"
     J_segment       398..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          105 a          135 c          124 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac agtctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc agtggttcca gcagaagcca ggccaggccc ctgtgttggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcaatgg ggcccaggca gaagatgagg ctgactatta
      361 ttgtcaatca gcagacagcg atggtaatca tccgttgttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004834             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:12966:9330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004834
VERSION     KCWK01004834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12966:9330"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..440
                     /note="immunoglobulin light chain variable region"
     V_region        95..440
     V_segment       95..403
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70572.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       404..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           94 a          162 c          111 g          111 t
ORIGIN      
        1 acatggggcc actgcaggga aagaggctgt gtccaccatg gcctggactc ctctcctcct
       61 cctgctcctc tctcactgca caggttccct ctcccagcct gtgctgaccc agccaacctc
      121 cctctcagca tctccgggag catcagccag actcagctgc accttgagca gtggaaatgt
      181 tggtagttac agcatattct ggtaccagca gaagccaggg agtcctcccc ggtaccttct
      241 ttactactac tcagactcaa gtaaccacca ggactctgga gtccccagcc gcttctctgg
      301 atcgaaagat gcttcagcca atgcagggct tttactgatc tctgggctcc agtctgaaga
      361 tgaggctgac tattactgtg ccacatggca cagcagcgct tcttacatct tcggtgctgg
      421 gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01004835             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:12141:9795
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004835
VERSION     KCWK01004835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12141:9795"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70573.1"
                     /translation="DYCCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          157 c          120 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagct tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagtcagg gagtcctccc cggtatcttc
      241 taagatacaa atcagactca gatcagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacgggga ttttacacgt ctctgggctc cagtctgagg
      361 atgaggctga ctattgctgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004836             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:19235:9325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004836
VERSION     KCWK01004836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19235:9325"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70574.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           94 a          143 c          132 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaatta aaactgtaca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtaagcg gcccacaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004837             339 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:7496:17192
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004837
VERSION     KCWK01004837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 339)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7496:17192"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..301
                     /note="immunoglobulin light chain variable region"
     V_region        5..301
     V_segment       5..266
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <229..>273
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70575.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       271..301
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        302..>339
                     /gene="IGLC"
BASE COUNT           71 a          101 c           86 g           81 t
ORIGIN      
        1 acatgggctc ctggacagtc ggtcaccatc tcctgcactg gaaccagcag tgatattggg
       61 tattatcatg ctgtgtcttg gtaccagcat catccaggca aagcccccaa actcatgatt
      121 tatgaggtca ataaacggcc cgcaggggtc tctgatcgct tctctggctc caagtctggc
      181 aacacggcct ccctgaccat ctctgggctc cagactgagg atgaggctga ttattactgc
      241 agctcatatg gaggcagcaa tagtttattc ttcggaggag ggacccggct gaccgtccta
      301 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004838             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:15807:8391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004838
VERSION     KCWK01004838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15807:8391"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70576.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          158 c          122 g          107 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata atgtgtcctg gtaccagcac ctcccaggaa
      241 cagctcccaa actcctcatc tattataatg atcaacgagg ctcaggtgtc tctgaccgac
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcgtggg atgatagcct gagcagttac atcttcgctg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01004839             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:10581:14309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004839
VERSION     KCWK01004839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:10581:14309"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70577.1"
                     /translation="DYYCQSYDRTLTAVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           94 a          155 c          129 g          109 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cccgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg agcagctcca acattggaga ttattatgtg cagtggtacc agcagcttcc
      241 aggaacggcc cccagactcc tcatctatga aaataataag cgacgctcag ggacttctga
      301 tcgattctct ggctcccagt ctggtacctc agcctcgctg accataagtg gactccagtc
      361 tgaggatgag gctgactatt actgccagtc ttatgacaga accttgactg ctgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01004840             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:24504:7961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004840
VERSION     KCWK01004840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24504:7961"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..440
                     /note="immunoglobulin light chain variable region"
     V_region        94..440
     V_segment       94..403
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70578.1"
                     /translation="DYYCSIGHSSGLYIF"
     J_segment       405..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>480
                     /gene="IGLC"
BASE COUNT           90 a          159 c          117 g          114 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggagc atcagccagt ctcacatgca ccttcaccgg tggcatcaat
      181 gttgctgtct accacataca ctggtaccag cagaagccag ggagtccccc ccggtttctt
      241 ctgaggtaca aatcagactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccagta atgcttcagc gaacacaggg attttacgca tttctgggct ccagtctgag
      361 gatgaggctg actattactg ttccattgga cacagcagcg gtctttacat cttcggtgct
      421 gggacccggc tcaccgtcct gggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004841             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:22988:13004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004841
VERSION     KCWK01004841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22988:13004"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70579.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          158 c          118 g          114 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcaag ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtctt atgatgctgt gtcttggtac caacagcctc caggcaaagc
      241 cccccaactc ataatttttg aggtcaataa gcggccctca ggggtctctg atcgcctctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgctgct catatgtagg cagcaacact tacatcttcg atgttgggac
      421 ccggctcacc gtcctaggtc agtccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004842             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:12817:8549
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004842
VERSION     KCWK01004842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12817:8549"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70580.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           93 a          152 c          118 g          106 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcaacg tctgaggccg ccaggaagag tgtcaccatc tcctgttctg gaagcaactc
      181 caacatcgga agttataatg tgtcctggta ccagcagctc ccaggaacag ctcccaaact
      241 cctcatctat tataatgatc aacgagcctc aggtgtctct gaccgattct ctggctccaa
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgcg gcatgggatg atagccttag cggttacatc ttcggtgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004843             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:20205:5165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004843
VERSION     KCWK01004843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20205:5165"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70581.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          147 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgaa ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004844             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:18239:17168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004844
VERSION     KCWK01004844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18239:17168"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..404
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70582.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       406..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           86 a          163 c          121 g          111 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt agtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa ccagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt tctgccaggt gtttgacagt agtgttgtgt tcttcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01004845             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:28090:13246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004845
VERSION     KCWK01004845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:28090:13246"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..430
                     /note="immunoglobulin light chain variable region"
     V_region        84..430
     V_segment       84..395
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70583.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       396..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>470
                     /gene="IGLC"
BASE COUNT           90 a          160 c          106 g          114 t
ORIGIN      
        1 acatggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc ctgctcctct
       61 ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc ctctcagcat
      121 ctccgggagc atcagccaga ctcagctgca cctttagcag tggcatcaat gttggtagtt
      181 atagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt ctctactact
      241 actcagactc aagtaaacac cagggctctg gagtccccag ccgcttctct ggatccaaag
      301 atgcttcggc caatgcaggc cttttactga tctctgggct ccagtctgaa gatgaggctg
      361 actattactg tgccatatgg cacagcagcg cttcttactt cttcggtact gggacccggc
      421 tcaccgtcct gggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004846             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:20346:9785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004846
VERSION     KCWK01004846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20346:9785"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..426
                     /note="immunoglobulin light chain variable region"
     V_region        103..426
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70584.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>465
                     /gene="IGLC"
BASE COUNT           92 a          148 c          128 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaagtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004847             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:22504:14148
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004847
VERSION     KCWK01004847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22504:14148"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70585.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          164 c          123 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004848             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:21634:17586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004848
VERSION     KCWK01004848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21634:17586"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70586.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          157 c          124 g          109 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01004849             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:12005:9946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004849
VERSION     KCWK01004849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12005:9946"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70587.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          161 c          121 g          108 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtact gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gaagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcaactgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaactaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag atgtatgaca gtagtgatgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004850             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:15657:4625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004850
VERSION     KCWK01004850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:15657:4625"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..380
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70588.1"
                     /translation="DYYCQVWDSSSDHWIF"
     J_segment       386..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           92 a          147 c          133 g           89 t
ORIGIN      
        1 acatgggggt ctcaggaggc agcattgacg gtgcctcagc catggcctgg acccttctcc
       61 tcctcggcct cctcgctcac tgcacagact ctgcgacctc ctatgagctg actcagccac
      121 cctcggtgtc agcggcctca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtaaata tgtgcactgg taccagcaga ggccaccgca ggcccctgtg caagtcatct
      241 atactgatag cagacggccc tcagggatcc ctgagcgatt ctctggctcc aactcaggga
      301 acaccgccac cctgaccatc agcgcggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cagtagtagt gatcattgga tattcggcgg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004851             398 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:17738:11250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004851
VERSION     KCWK01004851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 398)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17738:11250"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    39..360
                     /note="immunoglobulin light chain variable region"
     V_region        39..360
     V_segment       39..324
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <288..>332
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70589.1"
                     /translation="DYYCQVWDSSSEWVF"
     J_segment       325..360
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        361..>398
                     /gene="IGLC"
BASE COUNT           83 a          120 c          117 g           78 t
ORIGIN      
        1 acatggggct cctcgcttac tgcacagact ctgcgacctc ctatgagttg actcaggcac
       61 cctcagtgtc agcggcctca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      121 gaagtaaaac tgtgcactgg taccaacaga aggcagcgca ggcccctgtg ctggtcatct
      181 ttgctgatag caaacggccc tcagggatcc ctgaccgatt ctctggctcc aactcaggga
      241 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      301 aggtgtggga cagtagtagt gaatgggttt tcggcggagg gacccggcta accgtcctag
      361 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004852             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:17703:15475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004852
VERSION     KCWK01004852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:17703:15475"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..395
                     /note="immunoglobulin light chain variable region"
     V_region        76..395
     V_segment       76..363
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <326..>367
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70590.1"
                     /translation="TITVTPGGSSGTQF"
     J_segment       364..395
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        396..>433
                     /gene="IGLC"
BASE COUNT           83 a          137 c          118 g           95 t
ORIGIN      
        1 acatggggtg tctccaccat ggcctggact cctctctggc tcaccctcct cagtctttgc
       61 acaggttcta tggtttcttc tgagctgact caggaccctg cagtgtctgt ggccttgggg
      121 cagacagtca ggattacctg ccaaggagac agcctcagaa gctcttatgc aagctggtac
      181 caacagaggc caggccaggc ccctgtgctg gtcgtctatg gtaacaacta ccggccctca
      241 gggatcccag agcgattctc tggctcctac tcccgaaaca cagcttcctt gaccatcact
      301 ggggctcagg tggaagatga ggctgactat tactgtgact cctgggggca gcagcggaac
      361 ccaattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      421 cactctcttc ccg
//
LOCUS       KCWK01004853             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:12423:4067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004853
VERSION     KCWK01004853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12423:4067"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70591.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          155 c          126 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtaac catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acatctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcggcatgg gatgatagcc tgagaggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004854             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:11435:12960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004854
VERSION     KCWK01004854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11435:12960"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..312
                     /note="immunoglobulin light chain variable region"
     V_region        8..312
     V_segment       8..275
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <240..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70592.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       276..312
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>350
                     /gene="IGLC"
BASE COUNT           74 a          105 c           90 g           81 t
ORIGIN      
        1 acatgggggg agcatcagcc agactcagct gcaccttgag cagtggcaat gttggtagtt
       61 acagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt ctttactact
      121 actcagactc aagtaaccac caggactctg gagtccccag ccgcttctct ggatcgaaag
      181 atgtttcagc caatgcaggg cttttactga tctctgggct ccagtctgaa gatgaggctg
      241 actattactg tgccacatgg cacagcagcg cttcttacat cttcgggggg gggacccggc
      301 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01004855             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:19471:4758
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004855
VERSION     KCWK01004855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19471:4758"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70593.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          148 c          128 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtacact ggtaccagca catgccaccg caggcccctg ttctgctcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttgttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004856             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:16213:10991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004856
VERSION     KCWK01004856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16213:10991"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..403
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70594.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       405..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           96 a          155 c          112 g          117 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcgcagcctg tgctgactca gccaacctcc
      121 ctctcagctt ctcctggagc atcagccaga ctcacctgca ccttgaacag tggcatcagt
      181 gttgctaatt acaggatatt ctggtaccac cagaagccag ggagtcctcc ccggtatctt
      241 ctgaactacc acacagactc agatattcac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatgcaggg attttactca tctctggact ccagtctgag
      361 gatgaggctg actattactg tatgatttgg cacaacaatg cttattgggt tttcggcgga
      421 gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004857             276 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:22489:16743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004857
VERSION     KCWK01004857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 276)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 276)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..276
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22489:16743"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..238
                     /note="immunoglobulin light chain variable region"
     V_region        9..238
     V_segment       9..199
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <166..>210
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70595.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       204..238
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        239..>276
                     /gene="IGLC"
BASE COUNT           54 a           86 c           70 g           66 t
ORIGIN      
        1 acatgggtga agccagggag tcctccccgg ttccttctgt actactactc agactcaaat
       61 aatcaccagg gctctggagt ccccagccgc ttctctggat ccaaagatgc ttcagccaat
      121 gcagggcttt tactgatctc tgggctccag tctgaagatg aggctgacta ttactgtgcc
      181 atgtggcaca gcagcgctta tgccttattc ggaggaggga cccggctgac cgtcctaggt
      241 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004858             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:20045:20003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004858
VERSION     KCWK01004858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20045:20003"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..427
                     /note="immunoglobulin light chain variable region"
     V_region        107..427
     V_segment       107..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70596.1"
                     /translation="DYHCQVWDINSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          141 c          137 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gtctctgcgg cctctaatga tctgacgcag
      121 ccaccctcga tttcagtgtc cccaggacag acggccaggc tgacctgtgg gggagacaac
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atctatgctg acagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgag catcagcggg gtcgaggccg gggatgaggc tgactatcac
      361 tgtcaggtgt gggacattaa tagtcatcat ctgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004859             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:4931:12460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004859
VERSION     KCWK01004859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4931:12460"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70597.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          158 c          128 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacgg aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtc cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaggca gctccaacat cggcagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctggccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004860             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:20461:4310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004860
VERSION     KCWK01004860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20461:4310"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..408
                     /note="immunoglobulin light chain variable region"
     V_region        63..408
     V_segment       63..369
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70598.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       371..408
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           81 a          152 c          109 g          104 t
ORIGIN      
        1 acatgggggc cctgactcct ctcctcctcc tgctcctctc tcactgcaca ggttccctct
       61 cccagcctgt gctgactcag ccaccctccc tgtctgcatc cccgggagca tcggccagac
      121 tcccctgcac cctgagcagt gacctcagtg ttggtagtaa aaacatgtac tggtaccagc
      181 agaagccagg gagcgctccc aggttattcc tgtactacta ctccgactca gacaagcagc
      241 tgggacctgg ggtccccaat cgagtctctg gctccaagga gacctcaagt aatacagcgt
      301 ttttgctcat ctctgggctc cagcctgagg acgaggccga ttatttctgc cagctgtttg
      361 acagtagtgt tgtgttcttc ggaggaggga cccgactgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004861             357 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:21143:8687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004861
VERSION     KCWK01004861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 357)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21143:8687"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..319
                     /note="immunoglobulin light chain variable region"
     V_region        6..319
     V_segment       6..282
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <244..>291
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70599.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       284..319
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        320..>357
                     /gene="IGLC"
BASE COUNT           73 a          104 c          109 g           71 t
ORIGIN      
        1 atggggactc agccaccctc gatttcagtg tccccaggac agacggccag ggtcacctgt
       61 gggggagaca acatcggagg tgaagttgtg aattggtacc agcagaagcc accgcaggcc
      121 cctgtgttgg tcatctatgc tgatagcgag cggccctcag ggatcccgga gcgattctct
      181 ggctccaaat cagggaacac ggccaccctg accatcagcg gggtcgaggc cggagatgag
      241 gctgactatt actgtcaggt gtgggacctt aatagtcatc atctgttatt cggaggaggg
      301 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004862             313 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:18897:11819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004862
VERSION     KCWK01004862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18897:11819"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..275
                     /note="immunoglobulin light chain variable region"
     V_region        8..275
     V_segment       8..238
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <206..>247
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70600.1"
                     /translation="DYHCQVYDGSAVLF"
     J_segment       242..275
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        276..>313
                     /gene="IGLC"
BASE COUNT           65 a           89 c           86 g           73 t
ORIGIN      
        1 acatggggac ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag
       61 cgctcccagg ttattcctgt actacttctc cgactcagac aagcagttgg gacctggggt
      121 ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc
      181 tgggctccag cctgaggacg aggccgatta tcactgtcag gtgtatgacg gtagtgctgt
      241 tttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      301 cactctcttc ccg
//
LOCUS       KCWK01004863             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:25360:7226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004863
VERSION     KCWK01004863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25360:7226"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70601.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           87 a          142 c          135 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccaaca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgcggccggg gatgtggctg actattactg
      361 tcaggtttgg gacatttata ctgatcatcc ggtgttgttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004864             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:23349:3223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004864
VERSION     KCWK01004864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23349:3223"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..447
                     /note="immunoglobulin light chain variable region"
     V_region        102..447
     V_segment       102..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70602.1"
                     /translation="DYHCQVYDGSAVLF"
     J_segment       414..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           87 a          160 c          126 g          112 t
ORIGIN      
        1 acatgggggg ggggtctgtg gcctcagagg tagccgtgtc caccatggcc ctgactcctc
       61 tcctcctcct gctcctctct cactgcacag gttccctctc ccagcctgtg ctgactcagc
      121 caccctccct gtctgcatcc ccgggagcat cggccagact cccctgcacc ctgagtagtg
      181 acctcagtgt tggtagtaaa aacatgtact ggtaccagca gaagccaggg agcgctccca
      241 ggttattcct gtactacttc tccgactcag acaagcagtt gggacctggg gtccccaatc
      301 gagtctctgg ctccaaggag acctcaagta acacagcgtt tttactcatc tctgggctcc
      361 agcctgagga cgaggccgat tatcactgtc aggtgtatga cggtagtgct gttttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004865             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:23027:23725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004865
VERSION     KCWK01004865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23027:23725"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70603.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          148 c          130 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004866             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:7402:19332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004866
VERSION     KCWK01004866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7402:19332"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..389
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70604.1"
                     /translation="DYYCSSYAGRNSFLF"
     J_segment       399..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           82 a          154 c          124 g          111 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 cctccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tgggaccagc
      181 agtgatgttg ggtattctca tgctgtgtct tggtaccaac agcatccagg caaagccccc
      241 aaactcatga tttatgatgt cagtaagcgg ccctcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggg tccaggctga ggatgaggct
      361 gattattact gcagctcata tgcaggcagg aactctttct tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004867             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:26337:11335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004867
VERSION     KCWK01004867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:26337:11335"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70605.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          163 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcggctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004868             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:7188:16717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004868
VERSION     KCWK01004868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7188:16717"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70606.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       413..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           92 a          157 c          123 g          109 t
ORIGIN      
        1 actgggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct ctccttctca ctctgctggt tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag catctggggc ccccggacag agggtcacca tctcctgcat
      181 tagcagcagc tccaacatcg gggcggctta ttatgtatcc tggtaccaac agttcccagg
      241 aacagccccc aaactcctca tctatgaaaa taataagcga ccctcagggg tttctgaccg
      301 attctctggc tccaagtctg gtccctcagc ctccctgacc atcactggac tccaatctga
      361 ggatgaggct gattattact gtttagcatg ggataccagc ctgaattgga tcttcggcgg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01004869             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:9454:7346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004869
VERSION     KCWK01004869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9454:7346"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70607.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          155 c          126 g          113 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac cctctcctgc
      181 actgggagca gctccaacat tggagattat tatgtgcagt ggtaccagca gcttccagga
      241 acggccccca aactcctcat ctatgaaaat aataagcgac cctcaggggt ttctgatcga
      301 ttctctggct cccagtctgg tacctcagcc tccctgacca tcactggact ccagtctgac
      361 gatgaggctg attattactg tcagtcctat gatagcagcc tgagtgttgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004870             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:6958:5720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004870
VERSION     KCWK01004870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:6958:5720"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..397
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70608.1"
                     /translation="DYYCSSYAGSNTLVF"
     J_segment       402..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           88 a          157 c          119 g          106 t
ORIGIN      
        1 acatgggggg tctcaggagg cggcactctc gggacatctc caccatggcc tgggatctgc
       61 tcctcttcac cctcctcact cagggcacag gatcctgggc tcaggctgcc ctgactcagc
      121 ctccctcaat gtctgggtct cctggacagt cggtcaccat ctcctgcact ggaaccagca
      181 gtgacattgg tagttataac cgtgtctcct ggtaccaaca tcacccagac aaagccccca
      241 aagtcatgat ttatgagggc agtcagcggc cctcaggggt ctctgatcgc ttctctgcct
      301 ccaagtctgg caacacggcc tccctgacca tctctgggct ccaggctgag gatgaggctg
      361 attattactg cagctcatat gcaggcagca atactttggt tttcggcgga gggacccgcc
      421 taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004871             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:21179:15383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004871
VERSION     KCWK01004871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:21179:15383"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70609.1"
                     /translation="DYYCQVWGMTSDHPVF"
     J_segment       391..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          142 c          142 g           92 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccaatgatc tgactcagcc
      121 gccctcggtg tcagagtccc caggacagac ggccaggatc acctgtgggg gagacaaaat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgctggtcat
      241 ctctggtgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg ggcatgacta gtgatcatcc ggtattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004872             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:16619:14519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004872
VERSION     KCWK01004872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16619:14519"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..410
                     /note="immunoglobulin light chain variable region"
     V_region        80..410
     V_segment       80..371
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <335..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70610.1"
                     /translation="DYYCGAWDSSLSGYIF"
     J_segment       373..410
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>448
                     /gene="IGLC"
BASE COUNT           84 a          150 c          111 g          103 t
ORIGIN      
        1 acatgggggg acaatcttca tcatgacctg gtcccctctc ctcctcaccc ttctcattca
       61 ctgcacaggg tcctgggccc agtctgtcct gacgcagccg ccctcagtgt ctgcggcccc
      121 agggcagaag gtcaccatct cctgctctgg aagtagctcc aacatcggga gaaattctgt
      181 ctcctggtac cagcaggtcc caggaacggc ccccaaactc ctcacctatg acaatgataa
      241 gcgaccctca ggggtttctg accgattctc tggctccaag tctggttcct cagcctccct
      301 ggccatcact ggactccaga ctggagatga ggctgattat tactgcggag catgggatag
      361 cagtctgagt ggttacattt tcggtgctgg gacccggctc accgtcctag gtcagcccaa
      421 ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01004873             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:17308:10837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004873
VERSION     KCWK01004873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17308:10837"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70611.1"
                     /translation="DYYCAAWDDTLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           92 a          155 c          126 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcggg tccaatatcg gaagtaatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaag ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agcgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgataccctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01004874             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:6506:11532
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004874
VERSION     KCWK01004874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:6506:11532"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70612.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctac cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004875             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:20220:7182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004875
VERSION     KCWK01004875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20220:7182"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70613.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          142 c          132 g           94 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagt ctctgcgacc tcctatgaac tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaattaaa actgtgcact ggtaccagca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgat agtaaacggc cctcggggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004876             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11930:9782
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004876
VERSION     KCWK01004876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11930:9782"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..439
                     /note="immunoglobulin light chain variable region"
     V_region        93..439
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70614.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>479
                     /gene="IGLC"
BASE COUNT           90 a          164 c          110 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca tctaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaagga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtcctg ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004877             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:6725:7219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004877
VERSION     KCWK01004877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6725:7219"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70615.1"
                     /translation="DYYCQVYDSNAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          165 c          119 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg cagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctcta ctactactcc gactcagaca accaacgggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgccagg tgtatgacag taatgctgtt ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004878             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:18979:18254
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004878
VERSION     KCWK01004878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:18979:18254"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70616.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>460
                     /gene="IGLC"
BASE COUNT           94 a          144 c          124 g           98 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagccc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaagatc acctgctctg gagatgcact
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 cgatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004879             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:26765:19794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004879
VERSION     KCWK01004879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:26765:19794"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..410
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70617.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       412..448
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           96 a          160 c          120 g          110 t
ORIGIN      
        1 acatggggag cgcagcttca gctgtgggta cagaaggcag gactcaggac aatctccagc
       61 atggcctggt tccctctcgt cctcaccctc ctcactcact gtgcagggtc ctgggcccag
      121 tctgtgctga ctcagcctcc ctcagcgtct gaggccgcca ggaagagtgt caccatctcc
      181 tgttctggaa gcacctccaa catcggaagc aataatgtat cctggtacca gcagctccca
      241 ggaacagctc ccaaactcct cttttattat aatgatcaac gagcctcagg tgtctctgac
      301 cgattctctt gctccaagtc tggcacgtca gcctccctgg ccatcagtgg gctccagacc
      361 gaggatgagg ctgattatta ctgcgcatca tgggatgata ccctgagcgg ctacatcttc
      421 ggtgctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      481 ttcccg
//
LOCUS       KCWK01004880             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:13818:15994
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004880
VERSION     KCWK01004880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:13818:15994"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70618.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          163 c          122 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtggtaaaaa catgtactgg taccagcaga agccagggcg cgctcccagg
      241 tttttcctgt actacaactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcac gtatatgaca gtagtactaa tgtgttattc
      421 ggaggaggga cccgtctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004881             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:24197:16915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004881
VERSION     KCWK01004881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:24197:16915"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..391
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70619.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          156 c          121 g          103 t
ORIGIN      
        1 acatgggggc tcaggaagca gagcctggag catctccacc atggcctggg ctccactcct
       61 cctcaccctc ctcgctcact gcacagggtc ttgggctgag gttgtgttca ctcagcccca
      121 ttctgtgtcg gggtctccgg ggcagacggt caccatctcc tgcacccgca gcagtggcag
      181 cattgacaac ggctttgtgt actggtacca gcagcggccg ggcagcgctc ccaccactgt
      241 gatttacaaa gataaccaaa gaccctctgg ggtccctgat cggttctctg gctccatcga
      301 cagctcctcc aactctgcct ccctcaccat ctctggactg aaatctgagg acgaggctga
      361 ctattactgt cagtcttatg acagcagcag tgtattattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004882             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:23934:15812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004882
VERSION     KCWK01004882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:23934:15812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..237
                     /note="immunoglobulin light chain variable region"
     V_region        8..237
     V_segment       8..197
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <165..>209
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70620.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       204..237
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>275
                     /gene="IGLC"
BASE COUNT           59 a           80 c           74 g           62 t
ORIGIN      
        1 acatggggaa gccagggagt cccccccggt atcttctgag gtacaaatca gactcagata
       61 agggccaggg ctctggagtc cccagccgct tctctggatc caaagatgct tcagcgaaca
      121 cagggatttt acgcatatct ggactccagt ctgaggatga ggctgactat tactgtgcca
      181 ttggacacag cagcggtgat tatatcttcg gtggtgggac ccgtctcacc gtcctaggtc
      241 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004883             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:23083:10350
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004883
VERSION     KCWK01004883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23083:10350"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70621.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          162 c          118 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca acctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctata ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004884             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:4432:10671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004884
VERSION     KCWK01004884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:4432:10671"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..309
                     /note="immunoglobulin light chain variable region"
     V_region        8..309
     V_segment       8..272
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <237..>281
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70622.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       274..309
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        310..>347
                     /gene="IGLC"
BASE COUNT           72 a          107 c           89 g           79 t
ORIGIN      
        1 acatggggac tgtgtcccca ggagggacag tcactctcac ctgtgcttcc agcactggag
       61 cagtcaccag tggtcactct ccacactggt tccagcagaa acctggacaa gcccccaaga
      121 cactgattta taatacaaac tacagacact cctggactcc tgcccggttc tcaggctccc
      181 tccttggggg taaagctgcc ctgacactgt caggtgcgca gcctgaggat gaggctgagt
      241 attattgttt actgtactat agtggtgctc agctgttatt cggaggaggg acccggctga
      301 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004885             411 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:16269:12044
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004885
VERSION     KCWK01004885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 411)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16269:12044"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    25..373
                     /note="immunoglobulin light chain variable region"
     V_region        25..373
     V_segment       25..335
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <301..>345
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70623.1"
                     /translation="DYHCAIGHSSGPYIF"
     J_segment       337..373
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        374..>411
                     /gene="IGLC"
BASE COUNT           89 a          138 c           97 g           87 t
ORIGIN      
        1 acatggggca caggttccct ctccaagcct atgctgactc agccggcctc cctctcagca
       61 tctcctggag catcagtcag tctcacatgc accttcagcg gtggcatcaa tgttgctgac
      121 taccacacac actggtacca acagaagcca gggagtcccc cccgatatct tctgaaatac
      181 aaatcagaca cagaccaggg ccaggggtct ggagtcccca gccgcttctc tggatccaaa
      241 gatccttcag cgaacacagg gattttacgc atctctgggc tccagtctga ggatgaggct
      301 gactatcact gtgccattgg tcacagcagc ggtccataca tcttcggtgc tgggacccgg
      361 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01004886             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:24889:19647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004886
VERSION     KCWK01004886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24889:19647"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..274
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70624.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       277..314
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           75 a          106 c           93 g           78 t
ORIGIN      
        1 acatggggga gcatcagcca gtctcacatg caccttcagc ggtggcatca atgttgctgg
       61 ctaccacata cactggtacc agcagaagtc agggagtcct ccccggtatc ttctaagata
      121 caaatcagac tcagatcagg gccagggctc tggagtcccc agccgcttct ctggatccaa
      181 agatgcttca gcgaacacgg ggattttaca cgtctctggg ctccagtctg aggatgaggc
      241 tgactattac tgtgccattg ggcacagcag cggtgattac atcttcggtg ctgggacccg
      301 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01004887             274 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:25064:8166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004887
VERSION     KCWK01004887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 274)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 274)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:25064:8166"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..236
                     /note="immunoglobulin light chain variable region"
     V_region        7..236
     V_segment       7..199
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <167..>208
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70625.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       200..236
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        237..>274
                     /gene="IGLC"
BASE COUNT           56 a           83 c           73 g           62 t
ORIGIN      
        1 acatgggcag aagccaggga gcgctcccag gttattccta tactactact ccgactcaga
       61 caagcagctg ggacctgggg tccccaatcg agtctctggc tccaaggaga cctcaactaa
      121 cacagcgttt ttgctcatct ctgggctcca gcctgaggac gaggccgatt attactgtca
      181 ggtgtttgac agtagtgctg tgttattcgg aggagggacc cgactgaccg tcctaggtca
      241 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004888             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:21882:7278
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004888
VERSION     KCWK01004888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21882:7278"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..398
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70626.1"
                     /translation="DYYCGAGYGSGRSWQYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           97 a          148 c          129 g           99 t
ORIGIN      
        1 acatggggga tcctggcttc agaagcagca tctgggacat gtcagccatg gcctggacgc
       61 ctctcctcct cagcctcctc gctcactgca cagtctctgt ggcctcctat gaactgactc
      121 agccaccctc agtgtcggtg tccccaggac agacagccag catcacctgc tctggaaata
      181 aattggggga tgtatatgct tattggtacc aacagaagcc aggccaggcc cctatactgg
      241 tcatctccaa ggatagcaac cggccctcag ggatccctga gcgattctct ggctccaatt
      301 cagggaacac ggccaccctg accatcagaa gggtcgaggc tggggatgag gccgactatt
      361 actgtggtgc aggctatggc agtgggcgca gttggcagta catcttcggt gatgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004889             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:6912:17928
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004889
VERSION     KCWK01004889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6912:17928"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70627.1"
                     /translation="DYYCAIWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          163 c          108 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcttctcc gggagcatca gccagactca gctgcacctt gaacagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaact taccaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004890             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:24846:13731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004890
VERSION     KCWK01004890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24846:13731"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70628.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          160 c          119 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacgcg cctcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcatcatgg gatgataccc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004891             299 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:19859:11245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004891
VERSION     KCWK01004891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 299)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19859:11245"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..261
                     /note="immunoglobulin light chain variable region"
     V_region        6..261
     V_segment       6..225
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>233
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70629.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       229..261
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        262..>299
                     /gene="IGLC"
BASE COUNT           66 a           86 c           89 g           58 t
ORIGIN      
        1 acatgggggg agacaacatt ggaactaaaa ctgtgcactg gtaccagcag aagccaccgc
       61 agggccctgt attggtcatc tttgctgaca gtaaacggcc ctcagggatc cctgagcgat
      121 tctctggctc caactcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg
      181 atgaggctga ctattactgt caggtgtggg acagtagtag taaatggata ttcggcgggg
      241 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004892             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:21625:12849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004892
VERSION     KCWK01004892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21625:12849"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70630.1"
                     /translation="DYYCQVWDNSNKYAIF"
     J_segment       398..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          145 c          135 g           96 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactttac aggctctgcg gcctcctatg gattgactca
      121 gccacgctca gtgtccgtgt ccccgggaca gacggccagg atcacctgtg ggggagacaa
      181 gattggaagt aaaagtgtac actggtacca gcagaggcca ccgcaggccc ctgtactggt
      241 catctatgtt gatggcgacc ggccctcagg gatccctgaa cgattctctg gctccaactc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagt ctgactatta
      361 ctgtcaggta tgggataata gtaataaata cgcgatcttc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004893             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:23770:16796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004893
VERSION     KCWK01004893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23770:16796"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70631.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          148 c          132 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cggccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccgatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta agagtgtgca ctggtaccag cacaagccac cgcaggcccc tatcctggtc
      241 atctattatt ataccgaacg gccctcggcg atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacactac tattgatcat ggctttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004894             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:22296:15747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004894
VERSION     KCWK01004894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:22296:15747"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70632.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           98 a          142 c          130 g           92 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatgtc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga gctgactcag
      121 gcaccctcag tgtcagcggc ctcaggacag acggccagga tcacctgtgg cggagacaac
      181 attggaatta aaaatgtcca ctggtaccag cagaagccag cacaggcccc tgtggtagtc
      241 atctatgctg ataacaaacg gccctcaggg atccctgagc gactctctgg ctccaactca
      301 gggaatattg ccaccctgac catcagcagg gtcgaggccg gggatgaggc agactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg gtattcggcg gagggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004895             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:13755:7568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004895
VERSION     KCWK01004895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13755:7568"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70633.1"
                     /translation="DYYCALWYNSAWIF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          157 c          115 g          113 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctgt cacagcctgt gctgactcag ccggcctccc
      121 tctcagtatc tcctggaaca tcagtcagac tcacctgcac cttgcgcact ggcatcaatg
      181 ttggtggctc ctacatattc tggtaccaac agaagccagg gcgtcctccc cggtaccttc
      241 tgaactacta ctcagactca aataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcaggac ttttactgat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccttatggt acaacagcgc ttggatattc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004896             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:14983:20711
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004896
VERSION     KCWK01004896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14983:20711"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70634.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       401..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          154 c          111 g          116 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcttctcc tggagcatca gccagactca cctgcacctt gaacagtggc atcagtgttg
      181 ctaattacag gatattctgg taccaccaga agccagggag tcctccccgg tatcttctga
      241 actaccacac agactcagat attcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcagggattt tactcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtatg atttggcaca acaatgctta ttgggttttc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004897             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:18894:6042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004897
VERSION     KCWK01004897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18894:6042"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70635.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          161 c          123 g          109 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaaataac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctgt attattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004898             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:20512:16347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004898
VERSION     KCWK01004898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20512:16347"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..403
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70636.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       407..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           96 a          155 c          121 g          110 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc actctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata atgtgtcctg gtaccagcac ctcccaggaa
      241 cagctcccaa actcctcatc tattataatg atcaacgagg ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcgtggg atgatagcct gagtagttac atcttcgctg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaagacttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01004899             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:16515:10438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004899
VERSION     KCWK01004899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16515:10438"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70637.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          155 c          122 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccagca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacgct ttattcttcg gaggagggac
      421 ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004900             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:18447:20233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004900
VERSION     KCWK01004900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18447:20233"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..451
                     /note="immunoglobulin light chain variable region"
     V_region        121..451
     V_segment       121..412
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70638.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       421..451
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT           95 a          158 c          128 g          108 t
ORIGIN      
        1 acatgggggg gggaagctct gcttcagctg tgggcacagg aggcagcact caggacagtc
       61 tccagcatgg cctggtctct ccttctcact ctgctggttc actgcacagg gtcctgggcc
      121 cagtctgtgc tgacgcagcc gccctcagca tctggggccc ccggacagag ggtcaccatc
      181 tcctgcatta gcagcagctc caacatcggg gcggcttatt atgtatcctg gtaccaacag
      241 ttcccaggaa cagcccccaa actcctcatc catgaaaata ataagcgacc ctcaggggtt
      301 tctgaccgat tctctggctc caagtctggt ccctcagcct ccctgaccat cactggactc
      361 caatctgagg atgaggctga ttattactgt ttagcatggg ataccagcct gaattggatc
      421 ttcggcggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCWK01004901             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:10300:3587
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004901
VERSION     KCWK01004901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10300:3587"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70639.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          159 c          113 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004902             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:14915:16369
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004902
VERSION     KCWK01004902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14915:16369"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    67..405
                     /note="immunoglobulin light chain variable region"
     V_region        67..405
     V_segment       67..368
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70640.1"
                     /translation="DYHCQVYDGSAVLF"
     J_segment       372..405
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>443
                     /gene="IGLC"
BASE COUNT           83 a          142 c          117 g          101 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc
      121 cctgcaccct gagtagtgac ctcagtgttg gtagtaaaaa catgtactgg taccagcaga
      181 agccagggag cgctcccagg ttattcctgt actacttctc cgactcagac aagcagttgg
      241 gacctggggt ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgtttt
      301 tactcatctc tgggctccag cctgaggacg aggccgatta tcactgtcag gtgtatgacg
      361 gtagtgctgt tttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg
      421 ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004903             398 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:19250:14549
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004903
VERSION     KCWK01004903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 398)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19250:14549"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    27..360
                     /note="immunoglobulin light chain variable region"
     V_region        27..360
     V_segment       27..323
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <285..>332
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70641.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       324..360
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        361..>398
                     /gene="IGLC"
BASE COUNT           76 a          126 c          105 g           91 t
ORIGIN      
        1 acatgggggg cacaggatcc tgggctcagg ctgccctgac tcagcctcgc tcagtgtctg
       61 ggtctcctgg acagtcggtc accatctcct gcactggaac cagcagtgac atcggcggtt
      121 ataactatgt ctcctggtac caacaacatc cagacacagc ccccaaactc atgatttatg
      181 aggtcagtaa gcggccctca ggggtctctg atcgcttctc tggctccaag tctggcaaca
      241 cggcctccct gaccatctct gggctccagg ctgaggacga ggctgattat tactgctgct
      301 cacatgcagg cagtgatatt ttcgtgttat tcggaggagg gacccggctg accgtcctag
      361 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004904             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:16905:12962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004904
VERSION     KCWK01004904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16905:12962"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70642.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           81 a          156 c          128 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc gtctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattat tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004905             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:9227:6499
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004905
VERSION     KCWK01004905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9227:6499"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..390
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70643.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       395..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT          106 a          137 c          123 g          101 t
ORIGIN      
        1 acatgggggg ctgtggttct aggaggaaga gctctgggtg tctcaccatg acctggacca
       61 ctgttctgct cccctttctc actctctgca caggctctga ggcctcctat gagctgacac
      121 agccaccctc agtgtcagtg tccccaggac agacggccag gatcacctgc tctggagaaa
      181 tactggcaaa aaaatatact cagtggttcc agcagcagcc aggccaggcc cctttcctgg
      241 tgatatataa agacagtgag aggccctcag ggatccctga gcgattctct agctccagtt
      301 cagggacaac aattaccttg accatcagtg gggcccaggc agaagatgag gctgactatt
      361 actgtcaatc agtagacagc agtggaaatc ttccgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004906             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:7488:18188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004906
VERSION     KCWK01004906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7488:18188"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70644.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          155 c          120 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004907             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:13552:9575
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004907
VERSION     KCWK01004907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13552:9575"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70645.1"
                     /translation="DYYCQVFDDSAVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          161 c          121 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gaaataaaaa catatactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aaccagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtcat acagcgtttt tgctcatttc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtttgacg atagtgctgt attattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004908             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:10751:8545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004908
VERSION     KCWK01004908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10751:8545"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..215
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70646.1"
                     /translation="DYYCQVWDSTSKWTF"
     J_segment       220..251
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           63 a           84 c           84 g           58 t
ORIGIN      
        1 acatgggatt ggaactaaaa ctgtgcactg gtaccagcag aagccaccgc agggccctgt
       61 attggtcatc tttgctgata gtaaacggcc gtcagggatc cctgagcgat tctctggctc
      121 caactcaggg aacaccgcca ccctgaccat cagcagggtc gaggccgggg atgaggctga
      181 ctattactgt caggtgtggg acagtactag taaatggaca ttcggcgggg ggacccggct
      241 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01004909             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:7734:20153
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004909
VERSION     KCWK01004909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:7734:20153"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..425
                     /note="immunoglobulin light chain variable region"
     V_region        97..425
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70647.1"
                     /translation="DYYCAAWDDTLRGYIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>465
                     /gene="IGLC"
BASE COUNT           89 a          153 c          118 g          105 t
ORIGIN      
        1 acatggggtc agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaacagtgtc gccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattatg atgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaggtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatac cctgagaggt tacatcttcg gtgatgggac ccggctcacc
      421 gtccttggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004910             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:21046:10233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004910
VERSION     KCWK01004910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21046:10233"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70648.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       403..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           84 a          163 c          127 g           97 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcccgtggt gactcagtcg
      121 tcctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcggtggg
      181 cacagcgact acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggtatttg
      241 atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctga tcgcttctcc
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggagact ggcattcagg tgttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004911             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:8953:6801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004911
VERSION     KCWK01004911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:8953:6801"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70649.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          161 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc aaaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004912             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:22676:8201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004912
VERSION     KCWK01004912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22676:8201"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..394
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70650.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       408..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           88 a          156 c          122 g          110 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccccga
      121 ctcagactcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tattgggtat tatcatgctg tgtcttggta ccagcatcat ccaggcaaag
      241 cccccaaact catgatttat gaggtcaata aacggcccgc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag actgaggatg
      361 aggctgatta ttactgcagc tcatatgcag gcagcaacgc tttattcttc ggaggaggga
      421 cccgcctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004913             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:21656:9176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004913
VERSION     KCWK01004913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21656:9176"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70651.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          156 c          122 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc aacgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca actccaacat cggaagttat aatgtgtcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcggcatgg gatgatagcc ttagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004914             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:7090:15637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004914
VERSION     KCWK01004914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7090:15637"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70652.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           83 a          164 c          123 g          101 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggc
      181 cactacagct acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggttcttg
      241 atgtggctta agagtgatgg cagccacacc aagggggacg gggtccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatatt ggcatttggg tattcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004915             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:5377:6968
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004915
VERSION     KCWK01004915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:5377:6968"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70653.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          159 c          127 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaccgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004916             408 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:27702:11525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004916
VERSION     KCWK01004916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 408)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:27702:11525"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    43..370
                     /note="immunoglobulin light chain variable region"
     V_region        43..370
     V_segment       43..330
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <292..>342
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70654.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       334..370
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        371..>408
                     /gene="IGLC"
BASE COUNT           82 a          119 c          117 g           90 t
ORIGIN      
        1 acatgggtcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
       61 ccaccctcgg tgtcagtgtc cccaggaaag acggccagga tcacctgtgg gggagacaat
      121 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      181 atctatgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      241 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattac
      301 tgtcaggttt gggacattta tattgatcat ccggtgttat tcggaggagg gacccggctg
      361 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004917             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:27558:11428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004917
VERSION     KCWK01004917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:27558:11428"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70655.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          150 c          115 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 acagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004918             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:17013:14340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004918
VERSION     KCWK01004918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17013:14340"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70656.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          136 c          122 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gttccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004919             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:20460:4837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004919
VERSION     KCWK01004919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20460:4837"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70657.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          162 c          123 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtgttaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 tcattcctat actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tggactccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctaa tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004920             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:24819:18928
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004920
VERSION     KCWK01004920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24819:18928"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70658.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       391..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          147 c          135 g           93 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctatgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa tatgtgcact ggtaccagca gaagccagcg caggcccctg tgttggtcat
      241 ctatgctgat accagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggtgt cgaggccggg tatgaggctg actatttctg
      361 tcaggtgtgg gacgatagta gtgatcatcc ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004921             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:9377:10857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004921
VERSION     KCWK01004921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:9377:10857"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..248
                     /note="immunoglobulin light chain variable region"
     V_region        4..248
     V_segment       4..212
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <176..>220
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70659.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       213..248
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        249..>286
                     /gene="IGLC"
BASE COUNT           53 a           90 c           78 g           65 t
ORIGIN      
        1 acatgggggt tatgatggcg tctcctggta ccagcagcac tcagggacag cccccagact
       61 cctgatttat gatgtcacta agcggccctc aggggtctcg gatcgcttct ctggctccaa
      121 gtctggcaac acggcctccc tcaccatctc tgggctccag actgaggacg aggctgatta
      181 ttactgttgc tcatatagga gtggaaacac ttggctattc ggcggaggga cccggctgac
      241 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004922             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:14949:11361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004922
VERSION     KCWK01004922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14949:11361"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70660.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          156 c          117 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggaacatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catacactgg taccagcaga agccagggag tcctccccga tatcttctga
      241 gatacaaatc ggactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacaca gcagcggtga ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004923             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:19883:8195
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004923
VERSION     KCWK01004923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19883:8195"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70661.1"
                     /translation="DYYCQVWDTCLDHGLF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           88 a          147 c          129 g           98 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtcaaa gtgtgcactg gtaccagcac atgccaccgc aggcccctgt tctggtcatc
      241 ttttattata ccgaacggcc ctcaggaatc cctgagcgaa tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acacatgtct tgatcacggc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004924             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:16652:19177
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004924
VERSION     KCWK01004924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16652:19177"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..425
                     /note="immunoglobulin light chain variable region"
     V_region        79..425
     V_segment       79..390
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70662.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>465
                     /gene="IGLC"
BASE COUNT           87 a          160 c          105 g          113 t
ORIGIN      
        1 acatgggagg ctgtgtccac catggcctgg actcctctcc tcctcctgct cctctctcac
       61 tgcacaggtt ccctctccca gcctgtgctg acccagccaa cctccctctc agcatctccg
      121 ggagcatcag ccagactcag ctgcaccttt agcagtggca tcaatgttgg tagttacagc
      181 atattctggt accagcagaa gccagggagt cctccccggt accttctcta ctactactca
      241 gactcaagta aacaccaggg ctctggagtc cccagccgct tctctggatc caaagatgct
      301 tcggccaatg caggcctttt actgatctct gggctccagt ctgaagatga ggctgactat
      361 tactgtgcca tatggcacag cagcgcttct tacttcttcg gtagtgggac ccggctcacc
      421 gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004925             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:7338:22212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004925
VERSION     KCWK01004925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7338:22212"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70663.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          159 c          127 g          107 t
ORIGIN      
        1 acatgggggc tggggtctca gcaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcagcact cagggacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tactgttgct catataggag tggaaacact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004926             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:12390:11362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004926
VERSION     KCWK01004926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12390:11362"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70664.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>460
                     /gene="IGLC"
BASE COUNT           95 a          142 c          124 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaagatc acctgctctg gagatgcact
      181 gcaaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 cgatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004927             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:9283:8057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004927
VERSION     KCWK01004927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9283:8057"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70665.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          161 c          117 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctctgcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcactg
      181 ttgctgccta ccacatacac tggtaccaac agaagccagg gagtcctccc cggtatcttc
      241 tgaggttcaa atcagactca gataaggacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcctcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctactactgt gccattgggc acagcagcgg tgattacatc ttcggtggtg
      421 ggacccgcct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004928             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:22791:19653
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004928
VERSION     KCWK01004928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22791:19653"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70666.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          137 c          135 g          103 t
ORIGIN      
        1 atgggggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggaaagacgg ccaggatcac ctgtggggga gacaatattg
      181 gaagtgaagt tgtcaactgg taccagcaga agccaccgca ggcccctgtg gtggtcatct
      241 atgctgatta tgaacggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acacggccac cctgaccatc agcggagtcg aggccgggga tgaggctgac tattactgtc
      361 aggtttggga catttatatt gatcatccgg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004929             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:16485:12353
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004929
VERSION     KCWK01004929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16485:12353"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70667.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          142 c          132 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga attgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004930             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:24612:16773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004930
VERSION     KCWK01004930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24612:16773"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..404
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70668.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       406..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           86 a          161 c          122 g          112 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt agtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggttcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt tctgccaggt gtttgacagt agtgttgtgt tcttcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01004931             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:20265:4428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004931
VERSION     KCWK01004931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20265:4428"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70669.1"
                     /translation="DYYCAAWDDSLGGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          156 c          127 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgggaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004932             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:14670:6647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004932
VERSION     KCWK01004932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14670:6647"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70670.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          160 c          115 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 ctgcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatacaaatc agactcagat aaggaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ctcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ctactgtgcc attgggcaca gcagcggtga ttacattttc gctgctggga
      421 cccgcctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004933             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:24063:18693
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004933
VERSION     KCWK01004933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24063:18693"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..454
                     /note="immunoglobulin light chain variable region"
     V_region        109..454
     V_segment       109..417
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70671.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       418..454
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           93 a          168 c          120 g          111 t
ORIGIN      
        1 acatgggggc ccaaccctgg gtctgtggcc tcagaggtag ccgtgtccac catggccctg
       61 actcctctcc tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg
      121 actcagccac cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg
      181 agcagtgacc tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc
      241 gctcccaggt tattcctata ctactactcc gactcagaca agcagctggg acctggggtc
      301 cccaatcgag tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct
      361 gggctccagc ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg
      421 ttattcggag gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCWK01004934             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:19987:13917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004934
VERSION     KCWK01004934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19987:13917"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..435
                     /note="immunoglobulin light chain variable region"
     V_region        87..435
     V_segment       87..395
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70672.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           94 a          153 c          115 g          111 t
ORIGIN      
        1 acatgggggg gaaagaggct gtgtccacca tggcctggac tcctctcctc ctcctgctcc
       61 tctctcactg cacaggttcc ctctccaagc ctatgctgac tcagccggcc tccctctcag
      121 catctcctgg agcatcagcc agtctcacat gcaccttcag cggtggcatc actgttgctg
      181 gctaccatat atattggtac cagcagaagc cagggagtcc cccccggtat cttctgaggt
      241 acaaatcaga ctcagataag ggccagggct ctggagtccc cagccgcttc tctggatcca
      301 aagatgcttc agcgaacaca gggattttac gcatatctgg actccagtct gaggatgagg
      361 ctgactatta ctgtgccatt ggacacagca gcggtgatta tatcttcggt gctgggaccc
      421 gtctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004935             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15745:9938
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004935
VERSION     KCWK01004935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15745:9938"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70673.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggtcgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004936             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:11365:12079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004936
VERSION     KCWK01004936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11365:12079"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..424
                     /note="immunoglobulin light chain variable region"
     V_region        106..424
     V_segment       106..392
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70674.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       393..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           88 a          145 c          128 g          101 t
ORIGIN      
        1 acatggggag ctgtgggctc agaagcagag ctctggggtg tctccaccat ggcctggact
       61 cctctctggc tcaccctcct cagtctttgc acaggttctc tggtttcttc tgacctgact
      121 caggaccctg ccgtgtctgt ggccttggga cagacagtca ggattacctg ccaaggagac
      181 agcctcagaa gctcttatgc aagctggtac cagcagaggc caggccaggc ccctgtgctg
      241 gtcgtctatg gtaacaacta ccggccctca gggatcccag agcgattctc tggctcctac
      301 tcacgaaaca cagcttcctt gaccatctct ggggctcagg tggaagatga ggctgactat
      361 tactgtgact cctgggacag cagcggaacc caattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004937             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:13918:19778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004937
VERSION     KCWK01004937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13918:19778"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70675.1"
                     /translation="HYYCQVWDINSDHVLF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          141 c          131 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgat gttgtgaatt ggtaccacca gaagccaccg caggcccctg tactggtcat
      241 ctatgctaat accgatcggc cctcagggat ccctgagcga ttctctggct ccatatcagg
      301 gaacacggcc accctgacca tcaacggggt cgaggccggg gatgaggctc actattactg
      361 tcaggtgtgg gacattaata gtgatcatgt gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004938             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:14519:9703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004938
VERSION     KCWK01004938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:14519:9703"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70676.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          145 c          129 g          100 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccttggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gtactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaataccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gtcccctcgg tcactctctt cccg
//
LOCUS       KCWK01004939             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:13012:22341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004939
VERSION     KCWK01004939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13012:22341"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70677.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT          106 a          137 c          121 g          100 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggctgac ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcag gctctgaggc ctcctatgac ctgacacagc
      121 caccctcagt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagaaatac
      181 tggcaaaaaa atatactcag tggttccagc agaagccagg ccagggccct agactggtga
      241 tatataaaga cagtgagagg ccctcaggga tccctgagcg attctctagc tccagttcag
      301 ggacaacagt taccttgacc atcagcgggg cccagacaga agatgaggct gactattact
      361 gtcaatcagc agacagaagt cctaatcatg tgtttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004940             500 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:21662:3915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004940
VERSION     KCWK01004940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 500)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21662:3915"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    144..462
                     /note="immunoglobulin light chain variable region"
     V_region        144..462
     V_segment       144..430
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <393..>434
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70678.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       431..462
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        463..>500
                     /gene="IGLC"
BASE COUNT           99 a          153 c          137 g          111 t
ORIGIN      
        1 acatggggtc ccttcctatg ataagagagg actggaggtt ccccttagct gtgggctcag
       61 aagcagagct ctggggtgtc tccaccatgg cctggactcc tctctggctc accctcctca
      121 gtctttgcac aggttctatg gtttcttctg agctgactca ggaccctgca gtgtctgtgg
      181 ccttggggca gacagtcagg attacctgcc aaggagacag cctcagaagc tcttatgcaa
      241 actggtacca acagaggcca ggccaggccc ctgtgctggt cgtctatggt aacaactacc
      301 ggccctcagg gatcccagag cgattctctg gctcctactc ccgaaacaca gcttccttga
      361 ccatcactgg ggctcaggtg gaagatgagg ctgactatta ctgtgactcc tgggacagca
      421 gcggaaccca attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      481 cctcggtcac tctcttcccg
//
LOCUS       KCWK01004941             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12570:8678
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004941
VERSION     KCWK01004941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12570:8678"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..387
                     /note="immunoglobulin light chain variable region"
     V_region        97..387
     V_segment       97..352
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <315..>359
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70679.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       354..387
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        388..>425
                     /gene="IGLC"
BASE COUNT           84 a          131 c          109 g          101 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg acagtcggtc accatctcct
      121 gcactggaac cagcagtgat gttgggtatt ataacgctgt gtcttggtac caacagcatc
      181 caggcaaagc ccccaaactc atgatttatg acgtcattaa gcggccctca ggggtttctg
      241 atcgcttctc tggctccaag tctggcgaca cggcctccct gaccatctct gggctccagg
      301 ctgaggatga ggctgattat tactgcagct catatgcagg cagaaataat tttttattcg
      361 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      421 tcccg
//
LOCUS       KCWK01004942             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:23281:9711
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004942
VERSION     KCWK01004942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:23281:9711"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70680.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       392..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          150 c          137 g           91 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag gctctgcgac ctcctatgag ctgactcagc
      121 caccctcggt gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa gtatgtgcac tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tctatgctga taccagacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg gtatgaggct gactatttct
      361 gtcaggtgtg ggacgatagc agtgatcatc cggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004943             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:8847:11961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004943
VERSION     KCWK01004943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8847:11961"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70681.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          163 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ccgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004944             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:16198:7859
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004944
VERSION     KCWK01004944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16198:7859"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..392
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70682.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       406..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           87 a          157 c          120 g          110 t
ORIGIN      
        1 acatggggct gggatctcag gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccccgact
      121 cagactccct ctgtgtccgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgatg ttgggtatta tcatgctgtg tcttggtacc agcatcatcc aggcaaagcc
      241 cccaaactca tgatttatga ggtcaataaa cggcccgcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccagac tgaggatgag
      361 gctgattatt actgcagctc atatgcaggc agcaacgctt tattcttcgg acgagggacc
      421 cgcctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004945             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:11159:18225
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004945
VERSION     KCWK01004945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11159:18225"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    42..375
                     /note="immunoglobulin light chain variable region"
     V_region        42..375
     V_segment       42..338
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>347
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70683.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       339..375
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        376..>413
                     /gene="IGLC"
BASE COUNT           73 a          139 c          110 g           91 t
ORIGIN      
        1 acatgggcac tctcctcctt cactgcacag ggtctctctc ccagcctgtg ctgactcagt
       61 cgccctctgc ctctgcctcc ctgggagcct cggtcaagct cacctgcact ctgagcagtg
      121 gccactacag ctacaccatc gcatggcatc agcagcagca agggaaggcc cctcggttct
      181 tgatgtggct taagagtgat ggcagccata ccaaggggga cggggtccct gatcgcttct
      241 caggctccag ctccggggct gagcgctacc tcaccatctc caacctccag tctgaggatg
      301 aggctgatta ttactgtcag acctgggata ttggcatttg ggtattcggc ggagggaccc
      361 ggctaaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004946             405 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:10542:11153
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004946
VERSION     KCWK01004946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 405)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:10542:11153"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    139..365
                     /note="immunoglobulin light chain variable region"
     V_region        139..365
     V_segment       139..331
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <295..>339
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70684.1"
                     /translation="DYYCCSRSSSSTYVF"
     J_segment       332..365
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>405
                     /gene="IGLC"
BASE COUNT           69 a          142 c          100 g           94 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggtac caacaacacc caggcaaagc ccccaaagtc
      181 atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc tggctccaag
      241 tctggcaaca cggcctccct gaccatctct gggctccagt ctgaggacga ggctgattat
      301 tactgttgtt cacgttcaag cagcagcact tacgtcttcg gtcctgggac ccggctcacc
      361 gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01004947             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:10943:9896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004947
VERSION     KCWK01004947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:10943:9896"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70685.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           92 a          159 c          122 g          113 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cacttcacag ttccagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg gccagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggagat tattttgtcc agtggtacca gcaccttcca
      241 ggaacggccc ccaaactcct catctatgaa aataataagc gaccctcagg gatttctgat
      301 cgattctctg gctcccagtc tggaacctca gcctccctga ccatcactgg actccagtcc
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtttgattgc tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004948             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:8418:14306
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004948
VERSION     KCWK01004948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:8418:14306"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..378
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70686.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       380..416
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           89 a          145 c          124 g           96 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacttttc tcctcctcgg
       61 cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc caccctcggt
      121 gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca ttggaagtca
      181 aagtgtacac tggtaccagc acaagccacc gcaggcccct gttctgctca tcttttatta
      241 taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag ggaacaccgc
      301 caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg
      361 ggacacaact attgatcacg gcttgttcgg aggagggacc cggctgaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004949             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:11872:14087
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004949
VERSION     KCWK01004949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11872:14087"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70687.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          147 c          130 g           98 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcttcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt caaagtgtgc actggtacca gcacaagcca ccgcaggccc ctgtactggt
      241 catcttttat tataccgaac ggccctcagg aatccctgag cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacacaa ctattgatca cggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004950             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:18589:17839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004950
VERSION     KCWK01004950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18589:17839"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70688.1"
                     /translation="DYYCQVWGSRSDHPVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          149 c          136 g           96 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca cagtctctgc gacctcctat gaactgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag ggtcacctgt ggggcaggta
      181 acattggaag taattttgtt cactggtacc agcagaagcc accgcaggcc cctgttcagg
      241 tcatctatgc agataacaga cggccctcag ggatccctga gcgattctct ggctccaatt
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtggggcagt cgtagtgatc atccggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004951             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:10952:18792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004951
VERSION     KCWK01004951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10952:18792"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70689.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       411..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           92 a          157 c          126 g          106 t
ORIGIN      
        1 acatggggag cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctga
      121 gctgactcag ccaccctcag cgtctggggc tcccgggcag agtgtcacca tctcctgctc
      181 tggaagcagc tccaatattg gaagtaattc tgtatactgg taccagcagt tcccaggaac
      241 ggcccccaaa ctcctcatct attatagtaa tcagcgaccc tcaggggtcc ctgaccgagt
      301 ctctggctct aagtcgggca cctcagcctc cctggccatc actggtctcc gatctgagga
      361 tgaggctgat tattactgtg cagcatggga tgacagcctg agaagtccgc tattcggcgg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01004952             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:22969:6391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004952
VERSION     KCWK01004952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22969:6391"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..396
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70690.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           93 a          156 c          117 g          108 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcatctcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 gactaccaca tacactggta ccagcagaag tcagggagtc ctccccggta tcttctaaga
      241 tacaaatcag actcagatca gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagcgaacac ggggatttta cacgtctctg ggctccagtc tgaggatgag
      361 gctgactatt actgtgccat tgggcacagc agcggtgatt acatcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01004953             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:20948:9242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004953
VERSION     KCWK01004953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20948:9242"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70691.1"
                     /translation="DYYCAAWDDSLYGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          156 c          126 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaaggaat agtgtatcct ggtaccagca ggtcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagcgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgtacggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01004954             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:11818:6180
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004954
VERSION     KCWK01004954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11818:6180"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..449
                     /note="immunoglobulin light chain variable region"
     V_region        116..449
     V_segment       116..412
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70692.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       415..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           89 a          160 c          131 g          107 t
ORIGIN      
        1 acatgggggg ctcattcctg gctgtggctc aggaagcaga gcctggagcg tctccaccat
       61 ggcctgggct ccactcctcc tcaccctcct cgctcactgc acagggtctt gggctgaggt
      121 tctgttcacg cagccccatt ctgtgtcggg gtctccgggg cagacggtca ccatctcctg
      181 tatccgcagc agaggcaaca ttgacaatag ttatgtgcag tggtaccagc agcgcccggg
      241 cagtgccccg accacagtga tttacagaga taaccaaaga gcctctgggg tccctgatcg
      301 gttctctggc tccatcgaca gctcctccaa ctctgcctcc ctcaccatct ctgggctgaa
      361 gtctgaggac gaggctgact actactgtca gtctactgat ggcaactaca atcggttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01004955             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:7190:21203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004955
VERSION     KCWK01004955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7190:21203"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70693.1"
                     /translation="DYYCAMWHSSASYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          162 c          112 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttgctagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tttactacta ctcagactca agtaaccacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgtttcggcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttcttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01004956             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:14055:20297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004956
VERSION     KCWK01004956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14055:20297"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70694.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       413..449
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           93 a          158 c          128 g          108 t
ORIGIN      
        1 acatggggaa gcgcagcttc agctgtgggt acagaaggca ggactcagga caatctccag
       61 catggcctgg ttccctctcg tcctcaccct cctcactcac tgtccagggt cctgggccca
      121 gtctgtgctg actcagcctc cctcagcgtc tgaggccgcc aggaacagtg tcgccatctc
      181 ctgttctgga ggcagctcca acatcggaag tcatagtgta tcctggtacc agcagctccc
      241 aggaacagct cccaaactcc tcatctatta tgatgatcaa cgagcctcag gtgtctctgg
      301 ccgattctct ggctccaggt ctggcacgtc agcctccctg gccatcagtg ggctccagac
      361 cgaggatgag gctgattatt actgcgcagc atgggatgat agcctgagag gttacatctt
      421 cggtgatggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      481 gttcccg
//
LOCUS       KCWK01004957             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:22119:5005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004957
VERSION     KCWK01004957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22119:5005"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70695.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       403..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          157 c          128 g          102 t
ORIGIN      
        1 acatgggggc tgtggctcag gaagcagagc ctggagcgtc tccaccatgg cctgggctcc
       61 actcctcctc accctcctcg ctcactgcac agggtcttgg gctgaggttc tgttcacgca
      121 gccccattct gtgtcggggt ctccggggca gacggtcacc atctcctgta cccgcagcag
      181 aggcaacatt gacaatagtt atgtgcagtg gtaccagcag cgcccgggca gtgccccgac
      241 cacagtgatt tacagagata accaaagagc ctctggggtc cctgatcggt tctctggctc
      301 catcgacagc tcctccaact ctgcctccct caccatctct gggctgaagt ctgaggacga
      361 ggctgactac tactgtcagt ctactgatgg caactacaat cggttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004958             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14530:13181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004958
VERSION     KCWK01004958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14530:13181"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    57..405
                     /note="immunoglobulin light chain variable region"
     V_region        57..405
     V_segment       57..365
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70696.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       375..405
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>443
                     /gene="IGLC"
BASE COUNT           87 a          147 c          105 g          104 t
ORIGIN      
        1 acatggggac tcctctcctc ctcctgctcc tctctcactg cacaggttcc ctctccaagc
       61 ctatgctgac tcagccggcc tccctctcag catctcctgg aacatcagcc agtctcacat
      121 gcaccttcag cggtggcatc aatgttgctg gctaccacat acactggtac cagcagaagc
      181 cagggagtcc tccccgatat cttctgagat acaaatcgga ctcagataag ggccagggct
      241 ctggagtccc cagccgcttc tctggatcca aagatgcttc agcgaacgca gggattttac
      301 gcatctctgg gctccagtct gaggatgagg ctgactatta ctgtgccatt gggcacagca
      361 gcggtgatta tattttcggt gctgggaccc ggctcaccgt cctaggtcag cccaaggctt
      421 cccccacggt cactctgttc ccg
//
LOCUS       KCWK01004959             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:9062:21157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004959
VERSION     KCWK01004959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9062:21157"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70697.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          139 c          135 g          100 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 cagcctcggt gtcagtgtcc ccgggacaga cggccaggat cacctgtggg ggagacaata
      181 ttggaagtaa aaatgtgcac tggtaccagc aggagccacc gcaggcccct gtgttggtca
      241 tcttttatga taacaaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacatcgc caccctgacc atcagcgagg ccgaggccgg ggatgaggct gactattact
      361 gtcagctgtg ggacagtagt gttgatcatg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004960             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:15741:12511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004960
VERSION     KCWK01004960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15741:12511"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..388
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70698.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       402..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           89 a          152 c          119 g          110 t
ORIGIN      
        1 acatggggga tctcaggagg cagcgctctc aggacttctc caccatggtc tgggctctgc
       61 tcctcctcac cctcctcact cagggcacag gatcctgggc tcaggctgcc ccgactcaga
      121 ctccctctgt gtccgggtct cctggacagt cggtcaccat ctcctgcact ggaaccagca
      181 gtgatattgg gtattatcat gctgtgtctt ggtaccagca tcatccaggc aaagccccca
      241 aactcatgat ttatgaggtc aataaacggc ccgcaggggt ctctgatcgc ttctctggct
      301 ccaagtctgg caacacggcc tccctgacca tctctgggct ccagactgag gatgaggctg
      361 attattactg tagctcatat gcaggcagca acagtttatt cttcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004961             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:13406:20003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004961
VERSION     KCWK01004961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13406:20003"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70699.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           81 a          158 c          127 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctccggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattac tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004962             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:12371:11868
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004962
VERSION     KCWK01004962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12371:11868"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70700.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          162 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggtg gtaaaaacat gtactggtac cagcagaagc cagggcgcgc tcccaggttt
      241 ttcctgtact acaactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcacgta tatgacagta gtactaatgt gttattcgga
      421 ggagggaccc gtctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01004963             505 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:8082:18958
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004963
VERSION     KCWK01004963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 505)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8082:18958"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    137..467
                     /note="immunoglobulin light chain variable region"
     V_region        137..467
     V_segment       137..430
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <395..>439
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70701.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       432..467
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        468..>505
                     /gene="IGLC"
BASE COUNT          107 a          161 c          124 g          113 t
ORIGIN      
        1 acatggggag gagataaaga gccatcagaa tccagcccca gctctggagc cagggatccc
       61 ttccaatatc agcaccatgg cctggactct gctcctcctc cagttcctcc tcacttgctg
      121 cccagggtcc aattctcagg ctgtagtgac tcaggagccc tcaatgactg tgtccccagg
      181 agggacagtc actctcacct gtgcttccag cactggagca gtcaccagtg gtcactctcc
      241 acactggttc cagcagaaac ctggacaagc ccccaagaca ctgatttata atacaaacta
      301 cagacactcc tggactcctg cccggttctc aggctccctc cttgggggta aagctgccct
      361 gacactgtca ggtgcgcagc ctgaggatga ggctgagtat tattgtttac tgtactatag
      421 tggtgctcag ctgttattcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc
      481 tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004964             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:7651:15910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004964
VERSION     KCWK01004964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7651:15910"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..451
                     /note="immunoglobulin light chain variable region"
     V_region        130..451
     V_segment       130..414
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70702.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       415..451
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT           97 a          150 c          136 g          106 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactcccca tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagccg
      181 gccaggatca cctgctctgg agatgtattg ccaaaaaaat atgcttattg gttccagcag
      241 aagccaggcc agtcccctgt attggtcatc tctgaggaca ccgaacggcc ctctgggatc
      301 cctgagagat tctctggctc cagctcaggg acagtggcca ccttgactat cagtggggcc
      361 caggtggagg atgaagctga ctactactgt tactcagcag acagtagtgg tcatggcttc
      421 ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCWK01004965             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:21103:10241
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004965
VERSION     KCWK01004965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21103:10241"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70703.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       400..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           84 a          160 c          127 g           97 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtggtgac tcagtcgtcc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cggtgggcac
      181 agcgactaca ccatcgcatg gcatcagcag cagcaaggga aggcccctcg gtatttgatg
      241 tggcttaaaa gtgatggcag ccacagcaag ggggacggga tccctgatcg cttctccggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggagactggc attcaggtgt tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004966             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:11744:22478
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004966
VERSION     KCWK01004966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11744:22478"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..446
                     /note="immunoglobulin light chain variable region"
     V_region        113..446
     V_segment       113..409
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70704.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       410..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           87 a          162 c          132 g          103 t
ORIGIN      
        1 acatgggggc agtgtggctg cctcagcaga gccctgagga gtctgcacca tggcctggac
       61 cccaatcctc ctcctcctca ctctcctcct tcactgcaca gggtctctct cccagcctgt
      121 gctgactcag tcgccctctg cctctgcctc cctgggagcc tcggtcaagc tcacctgcac
      181 tctgagcagt ggacacagga gctacaccat cgcgtggcat cagcagcagc aagggaaggc
      241 ccctcgatac ttgatgtggc ttaaaagtga tggcagccac agcaaggggg acgggatccc
      301 tgatcgcttc tcaggctcca gctccggggc tgagcgctac ctcaccatct ccaacctcca
      361 gtctgaggat gaggctgatt attattgtca gacgtgggat attggcattt gggtgttcgg
      421 cggagggacc cggctaaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01004967             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:23755:7655
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004967
VERSION     KCWK01004967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23755:7655"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..377
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70705.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       384..416
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           83 a          146 c          133 g           92 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacttttc tcctcctcgg
       61 cctccttgct tactgcacag actctgcggc ctcccatgat ctgactcagc caccctcggt
      121 gaccgtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga ttcgaagtga
      181 agttgtgaac tggtaccagc agaagccagc gcaggcccct gtattggtca tctttgctga
      241 taccgaacgg cccgcaggga tccccgagcg attctctggc tccaaatcag ggaacacggc
      301 caccctgacc atccgcgggg tcgaggccgg ggatgaggct gacttttact gtcaggtgtg
      361 ggacattcgt agtgatcgtc cgctattcgg cggagggacc cggctcaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004968             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:22567:3825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004968
VERSION     KCWK01004968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22567:3825"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..407
                     /note="immunoglobulin light chain variable region"
     V_region        87..407
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70706.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       372..407
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>446
                     /gene="IGLC"
BASE COUNT           90 a          140 c          118 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aagatcacct gctctggaga tgcactgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcgtcgat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg atgctgacta ctactgttac tcagcagaca
      361 gcagtggtta tggcttattc ggaggaggga cccggctgac cgtcctacgt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004969             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:12362:5299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004969
VERSION     KCWK01004969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12362:5299"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70707.1"
                     /translation="DYYCQVYDNSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          159 c          125 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg acgcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagag gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggttc caaggagacc tcaggtaata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacaa tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004970             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:23940:19028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004970
VERSION     KCWK01004970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23940:19028"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-59"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70708.1"
                     /translation="DYYCEAWDSSLSGPVF"
     J_segment       409..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          159 c          124 g          102 t
ORIGIN      
        1 acatggggag cttcaactgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactatgca ggatcctggg cccagtctgt
      121 gctgactcag ccaccctcag cgtctggggc ccccgggcag agtgtcacca tctcttgctc
      181 tggaagcagc tccaacatca gaggtaatgg tgtacactgg taccagcagc tctcaggaat
      241 ggcccccaaa ctcctcatct ataataataa tcagcgaccc tcaggggtcc ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc actggtctcc agtctgagga
      361 tgaggccgat tattactgcg aagcatggga tagcagcctg agcggtccgg tattcggcgg
      421 agggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01004971             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:20821:9233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004971
VERSION     KCWK01004971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20821:9233"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..433
                     /note="immunoglobulin light chain variable region"
     V_region        108..433
     V_segment       108..398
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70709.1"
                     /translation="DYYCQSADGNYRVF"
     J_segment       399..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>472
                     /gene="IGLC"
BASE COUNT           86 a          163 c          122 g          101 t
ORIGIN      
        1 acatgggggc tgtgactcag aaagcagagc ctggggcgtc tccaccatgg cctgggctcc
       61 actcctcctc accctcctcg ctcactgcac agggtcttgg gctgaacttg tgttcactca
      121 gccccattct gtgtcggggt ctccggggca gacggtcacc atctcctgca cccgcagcat
      181 tggcaacatt gacagtgaat atgtgcagtg gtaccagcag cgcccgggca gtgcccccac
      241 cacactgatt tacaaagata gtcaaagacc ctctggggtc cctgaccggt tctctggctc
      301 catcgacagc tcctccaact ctgcctccct cgccatctct gggctacagt ctgaggacga
      361 ggctgactac tactgtcagt ctgctgatgg caactacagg gtcttcggcg gagggacccg
      421 gctaaccgtc ctaagtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004972             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:16936:14579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004972
VERSION     KCWK01004972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16936:14579"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70710.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          162 c          111 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcaactcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 cttacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaaaatgc ttcaacgaac acaggcattt tacacatctc tgggctccag tctgaggatg
      361 aggctgacta tttctgtgcc attggacaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004973             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:8445:3919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004973
VERSION     KCWK01004973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8445:3919"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70711.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           89 a          146 c          129 g           98 t
ORIGIN      
        1 atggggtggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtcaaa gtgtacactg gtaccagcac aagccaccgc aggcccctgt tctggtcatc
      241 ttttattata ccgaacggcc ctcaggaatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acacaactat tgatcacggc ttgttcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004974             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:12759:19336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004974
VERSION     KCWK01004974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12759:19336"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70712.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       411..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          155 c          129 g          113 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggaggt tattatgtgc agtggtacca gcagcttcca
      241 ggagcggccc ccaaactcct catctatgaa aatgataaac gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tgattcctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gcttgagtgt tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01004975             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:19813:5061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004975
VERSION     KCWK01004975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19813:5061"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70713.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       396..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          141 c          139 g          102 t
ORIGIN      
        1 acatggggga gcctgacttt gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgctcacttt acaggctctg tggcctccta tgagttgcct
      121 cagccacgct cagtgtccgt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aacattggaa gtaatagtgt gcattggtac cagcagaagc caccgcgggc ccctgtattg
      241 gtcatctctg ttgatagcga acggccctca gggatccctg ggcgattctc tggttccaga
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggataa tatttataaa tacgcggtat tcggcggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004976             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:11465:11751
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004976
VERSION     KCWK01004976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11465:11751"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..432
                     /note="immunoglobulin light chain variable region"
     V_region        99..432
     V_segment       99..395
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70714.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       402..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           83 a          162 c          127 g           98 t
ORIGIN      
        1 acatgggggc agagccctga ggagtctgca ccatggcctg gaccccaatc ctcctcctcc
       61 tcctcactct cctccttcac tgcacagggt ctctctccca gcctgtggtg actcagtcgt
      121 cctctgcctc tgcctccctg ggagcctcgg tcaagctcac ctgcactctg agcggtgggc
      181 acagcgacta caccatcgca tggcatcagc agcagcaagg gaaggcccct cggtatttga
      241 tgtggcttaa aagtgatggc agccacagca agggggacgg gatccctgat cgcttctccg
      301 gctccagctc cggggctgag cgctacctca ccatctccaa cctccagtct gaggatgagg
      361 ctgattatta ctgtcagacc tgggagactg gcattcaggt gttcggcgga gggacccggc
      421 taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004977             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:12740:5982
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004977
VERSION     KCWK01004977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12740:5982"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70715.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           81 a          159 c          126 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttctg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgacgc
      361 tgattattac tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01004978             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:22935:13274
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004978
VERSION     KCWK01004978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22935:13274"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70716.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          158 c          127 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtggtg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcactctg agtagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgtt ctaccagtcc gactcagaca agcagcgggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgcaaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004979             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:17869:4456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004979
VERSION     KCWK01004979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17869:4456"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70717.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          147 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccaaca caagccacca caggccccta tcctggtcat
      241 ctattattat accgaacggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004980             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:27311:18220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004980
VERSION     KCWK01004980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:27311:18220"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..419
                     /note="immunoglobulin light chain variable region"
     V_region        74..419
     V_segment       74..382
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70718.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       383..419
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           87 a          149 c          118 g          103 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctcctgtgc tgactcagcc accctccctg tctgcatccc cgggagcatc
      121 ggccagactc ccctgcaccc tgagcagtga cctcagtgtt ggtgttaaaa acatgtactg
      181 gtaccagcag aagccaggga gcgctcccag gtcattccta tactactact ccgactcaga
      241 caagcagctg ggacctgggg tccccaatcg agtctctggc tccaaggaga cctcaagtaa
      301 cacagcgttt ttgctcatct ctggactcca gcctgaggac gaggccgatt attactgtca
      361 ggtgtatgac agtagtgcta atgtgttatt cggaggaggg acccggctga ccgtcctagg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004981             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17261:15734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004981
VERSION     KCWK01004981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17261:15734"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70719.1"
                     /translation="DYYCQVYDSSGNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          124 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtggtaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01004982             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:7025:12361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004982
VERSION     KCWK01004982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7025:12361"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70720.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          140 c          137 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccatga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01004983             331 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:15228:12605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004983
VERSION     KCWK01004983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 331)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:15228:12605"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..293
                     /note="immunoglobulin light chain variable region"
     V_region        4..293
     V_segment       4..258
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <221..>265
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70721.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       263..293
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        294..>331
                     /gene="IGLC"
BASE COUNT           69 a          100 c           82 g           80 t
ORIGIN      
        1 acatgggcag tcggtcacca tctcctgcac tggaaccagc agtgatattg ggtattatta
       61 tgctgtgtct tggtaccagc atcatccagg caaagccccc aagctcatga tttatgaggt
      121 caataaacgg cccgcagggg tctctgatcg cttctctggc tccaagtctg gcaacacggc
      181 ctccctgacc atctctgggc tccagactga ggatgagtct gattattact gcagctcata
      241 tgcaggcagc aacactttat tcttcggagg agggacccgg ctgaccgtcc taggtcagcc
      301 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01004984             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:16494:9958
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004984
VERSION     KCWK01004984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16494:9958"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70722.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          162 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01004985             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:20499:4155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004985
VERSION     KCWK01004985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20499:4155"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70723.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          148 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccagg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttcttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004986             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:23005:17245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004986
VERSION     KCWK01004986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23005:17245"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    36..384
                     /note="immunoglobulin light chain variable region"
     V_region        36..384
     V_segment       36..344
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <312..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70724.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       351..384
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>422
                     /gene="IGLC"
BASE COUNT           88 a          137 c          100 g           97 t
ORIGIN      
        1 atgggctcct ctctcactgc acaggttccc tctccaagcc tatgctgact cagccggcct
       61 ccctctcagc atctcctgga acatcagcca gtctcacatg caccttcagc ggtggcatca
      121 atgttgctgg ctaccacata tactggtacc accagaagcc agggagtccc ccccggtatc
      181 ttctgaggta caaatcagac tcagataagg gccagggctc tggagtcccc agccgcttct
      241 ctggatccaa agatgcttca gcgaacacag ggattttaca catctctgga ctccagtctg
      301 aggatgaggc tgactattac tgtgccattg gacacagcag cggtgattat atcttcggtg
      361 gtgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      421 cg
//
LOCUS       KCWK01004987             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:12115:20454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004987
VERSION     KCWK01004987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12115:20454"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70725.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       391..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           89 a          144 c          135 g           95 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaggtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tcctggtcat
      241 ctatgctaat aacgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg ggcgttacta gtgatcatcc cttattcgga ggagggaccc ggctgaccgt
      421 ccaaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01004988             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:22394:19237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004988
VERSION     KCWK01004988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22394:19237"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70726.1"
                     /translation="DYYCQVWGMTSDHPVF"
     J_segment       397..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          141 c          138 g           94 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcata gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgagtcag
      121 ccaccctcgg tgtcagtgtc cccaggagag acggccagga tcacctgtgg gggagacaaa
      181 attggaagtg aagtagtgaa ttggtaccag cagaagccac cgcaggcccc tatactggtc
      241 atctatgctg ataacgaacg gcccccaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt ggggcatgac tagtgatcat ccggttttcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01004989             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12389:5798
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004989
VERSION     KCWK01004989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12389:5798"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70727.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          160 c          119 g          107 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca actgcacctt gagcagtggc gtcaatgtgg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctgt
      241 actaccagtc agactcaagg aagcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggctgt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc ctatggcaca gcagcgcttc ttgcatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01004990             372 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:9205:17276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004990
VERSION     KCWK01004990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 372)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9205:17276"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..334
                     /note="immunoglobulin light chain variable region"
     V_region        8..334
     V_segment       8..297
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <262..>306
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70728.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       300..334
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        335..>372
                     /gene="IGLC"
BASE COUNT           73 a          118 c           97 g           84 t
ORIGIN      
        1 acatgggcct ccctctcagc atctccggga gcatcagcca gactcagctg caccttgagc
       61 agtggcgtca atgtgggtag ttacagcgta ttctggtacc agcagaagcc agggagtcct
      121 ccccggtacc ttctgtacta ccagtcagac tcaaggaaac accagggctc tggagtcccc
      181 agccgcttct ctggatccaa agatgcttca gccaatgcag ggctgttact gatctctggg
      241 ctccagtctg aagatgaggc tgactattac tgtgccctat ggcacagcag cgcttcttgc
      301 atcttcggtg gtgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      361 actctgttcc cg
//
LOCUS       KCWK01004991             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:9150:12051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004991
VERSION     KCWK01004991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9150:12051"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..446
                     /note="immunoglobulin light chain variable region"
     V_region        119..446
     V_segment       119..406
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70729.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           94 a          148 c          139 g          103 t
ORIGIN      
        1 acatggggga ggaacctgcc cagcctgggc ctcaggaggc agcattgacg gtgcctcagc
       61 catggcctgg acttttctcc tcctcggcct ccttgcttac tgcacaggct ctgcggcctc
      121 ctatgatctg actcagccac cctcggtgtc agtgtcccca ggacagacgg ccaggatcac
      181 ctgtggagga gacaacattg gaagtgaagt tgtcaactgg taccagcaga agccaccgca
      241 ggcccctgtg ctggtcatct atgctgatta tgaacggccc tcagggatcc ctgagcgatt
      301 ctctggctcc aaatcaggga acacggccac cctgaccatc agcggagtcg aggccgggga
      361 tgaggctgac tattattgtc aggtgtggga catttatatt gaccatccgg tgttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01004992             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:7308:9957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004992
VERSION     KCWK01004992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7308:9957"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70730.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       412..446
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           83 a          160 c          129 g          112 t
ORIGIN      
        1 acatgggggg ctcattcctg gctgtggctc aggaagcaga gcctggagca tctccaccat
       61 ggcctgggct ccactcctcc tcaccctcct cgctcactgc acagggtctt gggctgaggt
      121 tgtgttcact cagccccatt ctgtgtcggg gtctccgggg cagacggtca ccatctcctg
      181 cacccgcagc agtggcagca ttggcaacag ctatgtgtac tggttccagc agcggccggg
      241 cagcgtcccc actattgtga tttacaaaga tgaccaaaga ccctctgggg tccctgatcg
      301 attctctggc tccatcgaca gctcctccaa ctctgcctcc ctcaccatct ctggactgaa
      361 gtctggggac gaggctgact attactgtca gtcttttgac agcagcagtg tcttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01004993             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:17022:9707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004993
VERSION     KCWK01004993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17022:9707"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70731.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       392..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          149 c          134 g           94 t
ORIGIN      
        1 acatgggctg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag gctctgcgac ctcctatgag ctgactcagc
      121 caccctcggt gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa atatgtgcac tggtaccagc agaagccagc gcaggcccct gtgttggtca
      241 tctatgctga taccagacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcggtg tcgaggccgg gtatgaggct gactatttct
      361 gtcaggtgtg ggacgatagt agtgatcatc cggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01004994             498 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:6603:5012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004994
VERSION     KCWK01004994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 498)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:6603:5012"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..460
                     /note="immunoglobulin light chain variable region"
     V_region        130..460
     V_segment       130..423
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>432
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70732.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       426..460
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        461..>498
                     /gene="IGLC"
BASE COUNT           96 a          159 c          133 g          110 t
ORIGIN      
        1 acatggggag atttgggtga agcgcagctt cagctgtggg tacagaaggc aggactcagg
       61 acaatctcca ccatggcctg gttccctctc ctcctcaccc tcctcactca ctgtgcaggg
      121 tcctgggccc agtctgtgct gactcagcct ccctcagcgt ctgaggccgc caggaagagt
      181 gtcaccatct cctgttctgg aagcagctcc aacatcggaa gtaatagtgt atcctggtac
      241 cagcagctcc cagaaacggc tcccaaactc ctcatctttt ataatgatcg gcgagcctca
      301 ggtgtctctg accgattctc tggctccaag tctggcacgt cagcctccct ggccatcagt
      361 gggctccaga ccgaggatga ggctgattat tactgcgcag catgggatga tagcctgagc
      421 ggtccggtat tcggcggagg gacccgactg accgtcctag gtcagcccaa ggctgccccc
      481 tcggtcactc tcttcccg
//
LOCUS       KCWK01004995             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:21351:3105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004995
VERSION     KCWK01004995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21351:3105"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70733.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       404..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           86 a          162 c          124 g          106 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 caacagtgac atcggtggtt ataactatgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc gtgatttatg aggtcaatca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctgacaaca cggcctccct gaccatctct ggcctccagc ctgaggacga
      361 ggctgattat tactgcagct cgtatgcagg cagcgacact ttcgtgttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01004996             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:12323:19813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004996
VERSION     KCWK01004996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12323:19813"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..439
                     /note="immunoglobulin light chain variable region"
     V_region        94..439
     V_segment       94..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70734.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       403..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           94 a          162 c          110 g          111 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggaac atcagccaga ctcagctgca ccttgagcag tggcaatgtt
      181 ggtagttaca gcatattctg gtaccagcag aagccaggga gtcctccccg gtaccttctt
      241 tactactact cagactcaag taaccaccag gactctggag tccccagccg cttctctgga
      301 tcgaaagatg cttcagccaa tgcagggctt ttactgatct ctgggctcca gtctgaagat
      361 gaggctgact attactgtgc cacatggcac agcagcgctt cttacatctt cggtcctggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01004997             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:18642:17371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004997
VERSION     KCWK01004997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18642:17371"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70735.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          142 c          133 g           92 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg gtctgcgacc tcctatgaac tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa actgtgcact ggtaccagca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgat agtaaacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01004998             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:27109:12875
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004998
VERSION     KCWK01004998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:27109:12875"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70736.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       401..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          152 c          118 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcttctcc tggagcatca gccagactca cctgcacctt gagcagtggc atcagtgttg
      181 gtacttacag gatattctgg taccagcaga ggccagggag tcctccccgg tatcttctga
      241 accaccacac agactcagat aaacatcagg gctctggagt ccccggccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcagggattt tgctcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtatg atttggcaca acaatgctta tgtgttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01004999             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:10361:16189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01004999
VERSION     KCWK01004999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10361:16189"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70737.1"
                     /translation="DYYCQSGDSSGNHWVF"
     J_segment       389..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          103 a          132 c          127 g          101 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgtcacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 gactaaaaaa tatactctgt ggttccagca gaggccaggc caggcccctc tggtggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagaga ttctctagtt ccagttcagg
      301 gccaacagct accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagga gacagcagtg gtaatcattg ggtattcggc ggagggaccc ggctaagcgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005000             279 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:19874:9862
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005000
VERSION     KCWK01005000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 279)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19874:9862"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..239
                     /note="immunoglobulin light chain variable region"
     V_region        9..239
     V_segment       9..205
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <169..>213
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70738.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       206..239
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        240..>279
                     /gene="IGLC"
BASE COUNT           51 a           95 c           64 g           69 t
ORIGIN      
        1 acatggggct ctgtctcctg gtaccaacaa cacccaggca aagcccccaa actcatgatt
       61 tttggtgtca ataatcggcc ctctggggtc tctgaccgct tctctggctc caagtctggc
      121 aacacggcct ccctgaccat ctctgggctc cagtctgagg acgaggctga ttattactgt
      181 tgttcacatt caaccagtag cacttacgtc ttcggtcctg ggacccggct caccgtcctg
      241 ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005001             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:4883:14911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005001
VERSION     KCWK01005001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:4883:14911"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70739.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          147 c          132 g           95 t
ORIGIN      
        1 acaggggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gttctggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg aatctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaagt cttgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005002             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:16573:13137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005002
VERSION     KCWK01005002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16573:13137"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70740.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          155 c          126 g          111 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca agtcccagga
      241 acaactccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgatcga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgaggggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005003             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:22626:16866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005003
VERSION     KCWK01005003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22626:16866"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70741.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           90 a          157 c          126 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtcca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaac agtgtcgcca tctcctgttc
      181 tggaggcagc tccaacatcg gcagtcatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatgatga tcaacgagcc tcaggtgtct ctggccgatt
      301 ctctggctcc aggtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agaggttaca tcttcggtga
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01005004             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:13316:19336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005004
VERSION     KCWK01005004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13316:19336"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70742.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>465
                     /gene="IGLC"
BASE COUNT           90 a          137 c          135 g          103 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgcccctcg gtcactctct tcccg
//
LOCUS       KCWK01005005             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:17282:7515
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005005
VERSION     KCWK01005005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17282:7515"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70743.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       215..251
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           59 a           89 c           81 g           60 t
ORIGIN      
        1 acatggggga agtaagagtg tgcactggta ccagcacaag ccaccgcagg cccctatcct
       61 ggtcatctat tattataccg aacggccctc ggcgatccct gagcgattct ctggctccaa
      121 atcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      181 ttactgtcag gtgtgggaca ctactattga tcatggcttt ttcggaggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005006             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:11635:13512
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005006
VERSION     KCWK01005006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11635:13512"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70744.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          143 c          141 g           92 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag aagaagccag cgcaggcccc tgcactggtc
      241 atctatgctg atagcgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcaggggg gtcgaggccg ggggtgaggc tgactattac
      361 tgtcaggtgt gggacatgcg tagtgatcaa ccgctattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005007             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:19795:10063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005007
VERSION     KCWK01005007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19795:10063"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..437
                     /note="immunoglobulin light chain variable region"
     V_region        92..437
     V_segment       92..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70745.1"
                     /translation="DYYCAIWHSSAYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           97 a          160 c          108 g          110 t
ORIGIN      
        1 acatgggact gcagggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc ccagcctgtg ctgacccagc caacctccct
      121 ctcagcatct ccgggagcat caggcagact cagctgcacc ttgagcagtg acatcaatgt
      181 tggtacttac agcatattct ggtaccagca gaagccaggg agtcctcccc ggtaccttct
      241 gtactacaac tcagactcaa gtaaacacca gggctctgga gtccccagcc gcttctctgg
      301 atccaaagat gcttcagcca atgcaggact tttactgatc tctggtctcc ggtctgaaga
      361 tgaggctgac tattactgtg ccatatggca cagcagcgct tacatcttcg gtactgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005008             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:11095:16056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005008
VERSION     KCWK01005008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11095:16056"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70746.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          148 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccacgatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005009             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22588:6676
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005009
VERSION     KCWK01005009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22588:6676"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70747.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          161 c          123 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgt cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005010             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:16319:10179
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005010
VERSION     KCWK01005010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16319:10179"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70748.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       392..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          141 c          138 g           97 t
ORIGIN      
        1 acatggggct gactttggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactttacag gctctgcggc ctcctatgcg gtgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacagg cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa aagtgtccag tggtaccagc agacgccacc gcaggcccct gtactggtca
      241 tttatggtga tagggaacgg ccctcaggga tccctgaacg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggatagtagt agtaaatatg tcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005011             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:22795:5417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005011
VERSION     KCWK01005011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22795:5417"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..453
                     /note="immunoglobulin light chain variable region"
     V_region        117..453
     V_segment       117..410
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70749.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       416..453
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           97 a          158 c          124 g          112 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac atcggggcgg gttattatgt atcctggtac cagcagttcc
      241 caggaacagc ccccaaactc ctcatctatg aaaataataa acgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatcact ggactccaat
      361 ctgaggatga ggctgattat tactgctcag catgggatag cagcctgagt atcaattaca
      421 tcttcggttc tgggacccgt ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      481 ctctgttccc g
//
LOCUS       KCWK01005012             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:11538:7031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005012
VERSION     KCWK01005012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11538:7031"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..426
                     /note="immunoglobulin light chain variable region"
     V_region        96..426
     V_segment       96..389
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70750.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       390..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          154 c          120 g          104 t
ORIGIN      
        1 acatgggaca gaaggcagga ctcaggacaa tctccagcat ggcctggttc cctctcgtcc
       61 tcaccctcct cactcactgt gcagggtcct gggcccagtc tgtgctgact cagcctccct
      121 cagcgtctga ggccgccggg aagagggtct ccatctcctg ttctggaagc agctccaaca
      181 tcggaagtca tagtgtctcc tggtaccagc agctcccagg aacagctccc aaactcctca
      241 tctattatag tgatcaacga gcctcaggtg tctctgaccg attctctggc tctcagtctg
      301 gcacgtcagc ctccctggcc atcagtgggc tccagaccga ggatgaggct gattattact
      361 gcgcagcatg ggatgatagc ctgagcggtt acatcttcgg tgctgggacc cggctcgccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005013             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:10908:6953
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005013
VERSION     KCWK01005013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:10908:6953"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..303
                     /note="immunoglobulin light chain variable region"
     V_region        8..303
     V_segment       8..266
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70751.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       267..303
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           75 a          102 c           88 g           76 t
ORIGIN      
        1 acatgggggc cagactcccc tgcaccctga gcagtgacct cagtgttggt aataaaaaca
       61 tgtactggta ccaacagaag ccagggagcg ctcccaggtt attcctatac tactactccg
      121 actcagacaa gcagctggga cctggggtcc ccaatcgagt ctctggctcc aaggagacct
      181 caactaacac agcgtttttg ctcatctctg ggctccagcc tgaggacgag gccgattatt
      241 actgtcaggt gtttgacagt agtgctgtgt tattcggagg agggacccga ctgaccgtcc
      301 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005014             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:8541:13583
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005014
VERSION     KCWK01005014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:8541:13583"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70752.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       400..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          156 c          126 g          108 t
ORIGIN      
        1 acatgggggc tgtggctcag gaagcagagc ctggagcatc tccaccatgg cctgggctcc
       61 actcctcctc accctcctcg ctcactgcac agggtcttgg gctgaggttg tgttcactca
      121 gccccattct gtgtcggggt ctccggggca gacggtcacc atctcctgca cccgcagcag
      181 tggcagcatt ggcaacagct atgtgtactg gttccagcag cggccgggca gcgtccccac
      241 tattgtgatt tacaaagatg accaaagacc ctctggggtc cctgatcgat tctctggctc
      301 catcgacagc tcctccaact ctgcctccct caccatctct ggactgaagt ctggggacga
      361 ggctgactat tactgtcagt cttttgacag cagcagtgtc ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005015             295 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:9839:15422
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005015
VERSION     KCWK01005015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 295)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:9839:15422"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..257
                     /note="immunoglobulin light chain variable region"
     V_region        8..257
     V_segment       8..222
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <185..>229
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70753.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       224..257
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>295
                     /gene="IGLC"
BASE COUNT           61 a           84 c           76 g           74 t
ORIGIN      
        1 acatggggat gttgggtatt ataacgctgt gtcttggtac caacagcatc caggcaaagc
       61 ccccaaactc atgatttatg acgtcattaa gcggccctca ggggtttctg atcgcttctc
      121 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccagg ctgaggatga
      181 ggctgattat tactgcagct catatgcagg cagaaataat tttttattcg gaggagggac
      241 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005016             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:3893:16986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005016
VERSION     KCWK01005016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:3893:16986"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    69..393
                     /note="immunoglobulin light chain variable region"
     V_region        69..393
     V_segment       69..356
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <318..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70754.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       357..393
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>431
                     /gene="IGLC"
BASE COUNT           87 a          138 c          109 g           97 t
ORIGIN      
        1 acatgggcac catggcctgg acccctcccc tgctcatcct cctcactctc tgcacaggtt
       61 ccgtggtttc ctctgagctg actcaggagc ctgcattgtc tgtggccttg ggacaaacag
      121 tcaggatgac ctgccaagga gacagcctca aaacctatta tgcaagctgg taccagcaga
      181 agccaggcca ggtccctgtg ctggtcatct atggtaacaa ctaccggccc tcagggatcc
      241 caggccgatt ctctgtctcc tggtcaggaa acacaggttc cttgaccatc actgcggctc
      301 aggtggaaga tgaggctgac tattactgta agtcctggga cagcagtggt acccattaca
      361 tcttcggtgc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      421 ctctgttccc g
//
LOCUS       KCWK01005017             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:12086:6856
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005017
VERSION     KCWK01005017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12086:6856"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..269
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70755.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       270..306
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           75 a          107 c           86 g           76 t
ORIGIN      
        1 acatgggagc cagtctcaca tgcaccttca gcggtggcat caatgttgct aactaccaca
       61 tacactggta ccagcagaag ccagggagtc ctccccggta tcttctgaga tacaaatcag
      121 actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc aaagatgctt
      181 cagcgaacac agggatttta cgcatctctg ggctccagtc tgaggatgag gctgactatt
      241 actgtgccat tgggcacagc agcggtcctt acatcttcgg tcctgggacc cggctcaccg
      301 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005018             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:25528:12116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005018
VERSION     KCWK01005018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:25528:12116"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..227
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70756.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       231..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           67 a           85 c           90 g           59 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaactaa aactgtgcac tggtaccagc agaagccacc
       61 gcagggccct gtattggtca tctttgctga tagtaaacgg ccctcaggga tccctgagcg
      121 attctctggc tccaactcag ggaacaccgc caccctgacc atcagcaggg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg
      241 ggggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01005019             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:27152:6179
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005019
VERSION     KCWK01005019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:27152:6179"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70757.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          154 c          120 g          101 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgagctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctcct gctctggaag cagctccaat
      181 attggaagta attctgtata ctggtaccag cagttcccag gaacggcccc caaactcctc
      241 atctattata gtaatcagcg accctcaggg gtccctgacc gagtctctgg ctctaagtcg
      301 ggcacctcag cctccctggc catcactggt ccccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgacag cctgagaagt ccgctattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005020             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:22957:9768
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005020
VERSION     KCWK01005020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22957:9768"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70758.1"
                     /translation="DYYCSAWDSSLTGGFF"
     J_segment       407..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           97 a          154 c          124 g          107 t
ORIGIN      
        1 acatggggga gcttcagctg tggctagaga agacaggact caggacaatc tccagcatgg
       61 cctgcttccc tctcatcctc accgtcctca ctcactgtgc aggatcctgg gcccagtctg
      121 tgctgactca accaccctca gcgtctgggg cccccgggca gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaatt atgtatactg gtaccagcag ttctcaggga
      241 aggcccccaa actcctcatc cataataata atcagcgacc ctcaggggtc cctgatcgat
      301 tctctggctc caagtctggc acgtcagcct ccctggacat cagtgggctc cagtccgagg
      361 atgaggctga ttattactgc tcagcatggg atagcagtct gaccggtggc tttttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005021             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:9027:15554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005021
VERSION     KCWK01005021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9027:15554"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70759.1"
                     /translation="DYYCYSADSSGHDFF"
     J_segment       392..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          143 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatgactt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005022             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18375:18201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005022
VERSION     KCWK01005022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18375:18201"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70760.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       385..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           97 a          144 c          120 g           97 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gaagaattgc
      181 caaaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtc cagatcatct
      241 atgaggacag taaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactacc actggggccc aggtggagga tgaagctgac tactactgtt
      361 tctcaacaga caccagtggt aatcgggtat tcggcggagg gacccgtcta accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005023             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:10052:13492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005023
VERSION     KCWK01005023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:10052:13492"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..265
                     /note="immunoglobulin light chain variable region"
     V_region        1..265
     V_segment       1..228
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70761.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       229..265
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           67 a           84 c           89 g           63 t
ORIGIN      
        1 acatgggggg gagacaatat tggaagtaaa aatgtgcact ggtaccagca ggagccaccg
       61 caggcccctg tgttggtcat cttttatgat aacaaacggc cctcagggat ccctgagcga
      121 ttctctggct ccaaatcagg gaacatcgcc accctgacca tcagcgaggc cgaggccggg
      181 gatgaggctg actattactg tcagctgtgg gacagtagtg ttgatcatgg cttattcgga
      241 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      301 ccg
//
LOCUS       KCWK01005024             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:25031:4996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005024
VERSION     KCWK01005024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:25031:4996"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70762.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          158 c          121 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacgag cctcaggggt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005025             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12758:14378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005025
VERSION     KCWK01005025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12758:14378"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..440
                     /note="immunoglobulin light chain variable region"
     V_region        92..440
     V_segment       92..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70763.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       403..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           91 a          156 c          120 g          111 t
ORIGIN      
        1 acaggggggt gtggggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc caagcctatg ctgactcagc cggcctccct
      121 ctcagcatct cctggagcat cagccagtct cacatgcacc ttcagcggtg gcatcaatgt
      181 tgctgtctac cacatacact ggtaccagca gaagccaggg agtccccccc ggtatcttct
      241 gaggtacaaa tcagactcag ataagggcca gggctctgga gtccccagcc gcttctctgg
      301 atccagtaat gcttcagcga acacagggat tttacgcatt tctgggctcc agtctgagga
      361 tgaggctgac tattactgtg ccattggaca cagcagcggt ctttacatct tcggtgctgg
      421 gacccggctc agcgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01005026             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:25314:8361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005026
VERSION     KCWK01005026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:25314:8361"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70764.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          162 c          117 g          111 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctttct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt aataaaaaca tgtactggta ccaacagaag ccagggagcg ctcccaggtt
      241 attcctatac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caactaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtttgacagt agtgctgtgt tattcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01005027             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:20235:12881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005027
VERSION     KCWK01005027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20235:12881"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70765.1"
                     /translation="DYYCGIGHSSGLYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          156 c          118 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgaggctga ctattactgt ggcattggac acagcagcgg tctttacatc ttcggttctg
      421 ggacccggct cagcgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005028             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:13840:19450
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005028
VERSION     KCWK01005028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13840:19450"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..382
                     /note="immunoglobulin light chain variable region"
     V_region        91..382
     V_segment       91..344
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <307..>354
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70766.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       346..382
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>420
                     /gene="IGLC"
BASE COUNT           84 a          131 c          119 g           86 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gtgtccccag gacagacggc caggatcacc
      121 tgtgggggag acaacattgg aagtcaaagt gtgcactggt accagcacaa gccaccgcag
      181 gcccctgttc tggtcatctt ttattatacc gaacggccct caggaatccc tgagcgaatc
      241 tctggctcca aatcagggaa caccgccacc ctgaccatca gcggggtcga ggccggggat
      301 gaggctgact attactgtca ggtgtgggac acaagtcttg atcacggctt attcggagga
      361 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005029             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:24920:13463
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005029
VERSION     KCWK01005029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:24920:13463"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70767.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       393..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT          100 a          137 c          123 g          105 t
ORIGIN      
        1 acatggggct gtggttctag gaggaagagc tctgggtgtc tcaccatgac ctggaccact
       61 gttctgctcc cctttctcac tctctgcaca ggctctgagg cctcctatga ggtgacacag
      121 tcaccctcag tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagcaata
      181 ctggcaaata attatgctca gtggttccag cagaagccag accaggcccc tgtgttggtg
      241 atatataaag acactgagag gccctcaggg atccctgagc gattctctag ctccagttca
      301 gggacaacag ttaccttgac catcagtggg gcccaggcag aagatgaggc tgactattac
      361 tgtcaatcag ttgacagcag tgcccatcat ccgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccatggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005030             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:19333:8331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005030
VERSION     KCWK01005030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19333:8331"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..441
                     /note="immunoglobulin light chain variable region"
     V_region        111..441
     V_segment       111..404
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70768.1"
                     /translation="DYYCQSFDSSSVLF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           83 a          158 c          127 g          111 t
ORIGIN      
        1 acatggggat tcctggctgt ggctcaggaa gcagagcctg gagcatctcc accatggcct
       61 gggctccact cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt
      121 tcactcagcc ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc
      181 gcagcagtgg cagcattggc aacagctatg tgtactggtt ccagcagcgg ccgggcagcg
      241 tccccactat tgtgatttac aaagatgacc aaagaccctc tggggtccct gatcgattct
      301 ctggctccat cgacagctcc tccaactctg cctccctcac catctctgga ctgaagtctg
      361 gggacgaggc tgactattac tgtcagtctt ttgacagcag cagtgtctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005031             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:6152:16555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005031
VERSION     KCWK01005031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6152:16555"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70769.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          164 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 cctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005032             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:21788:2965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005032
VERSION     KCWK01005032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21788:2965"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70770.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           85 a          143 c          142 g           93 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tggaagtgaa gttgtgaact ggtaccagcg gaagccagcg caggcccctg tgctggtcat
      241 ctttgctgat agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg ggtgaggctg actattactg
      361 tcaggtgtgg gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005033             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15120:3196
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005033
VERSION     KCWK01005033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15120:3196"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70771.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           92 a          164 c          122 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggagtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005034             520 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:14867:11127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005034
VERSION     KCWK01005034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 520)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 520)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..520
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14867:11127"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    134..482
                     /note="immunoglobulin light chain variable region"
     V_region        134..482
     V_segment       134..445
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <410..>454
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70772.1"
                     /translation="DYHCQVYDSSTNALF"
     J_segment       448..482
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        483..>520
                     /gene="IGLC"
BASE COUNT           97 a          177 c          133 g          113 t
ORIGIN      
        1 acatggggac tgcgataaga gcggcctggg gcagcccaac cctgggtctg tggcctcaga
       61 ggtagccgtg tccaccatgg ccctgactcc tctcctcctc ctgctcctct ctcactgcac
      121 aggttccctc tcccagcctg tgctgactca gccaccctcc ctgtctgcat ccccgggagc
      181 atcggccaga ctcccctgca ccctgagcag tgacctcagt gttggtggta aaaacctgta
      241 ctggtaccag cagaagccag ggcgcgctcc caggtttttc ctgtactaca actccgactc
      301 agacaaggag ctgggacctg gggtccccaa tcgagtctct ggctccaagg agacctcaag
      361 taacacagcc tttttgctca tctctgggct ccagcctgag gacgaggccg attatcactg
      421 tcaggtatat gacagtagta ctaatgcgtt attcggagga gggacccgtc tgaccgtcct
      481 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005035             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:13516:7265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005035
VERSION     KCWK01005035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13516:7265"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70773.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          160 c          114 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggcgctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005036             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:14086:9369
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005036
VERSION     KCWK01005036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14086:9369"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..444
                     /note="immunoglobulin light chain variable region"
     V_region        123..444
     V_segment       123..408
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70774.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       412..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT          100 a          147 c          138 g           97 t
ORIGIN      
        1 acatgggatc aacgcagagt acatggggct gggtctcagg aggcagcatt gacggtgcct
       61 cagccatggc ctggaccctt ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga
      121 cctcctatga actgactcag tcaccctcag tgtcagcggc ctcaggacag ccggccagga
      181 tcacctgtgg gggagacaac attggaatta aaactgtaca ctggtaccag cagaagccac
      241 cgcagggccc tgtattggtc atctttgctg atagtaagcg gccctcaggg atccctgagc
      301 gattctctgg ctccaactca gggaacaccg ccaccctgac catcagcagg gtcgaggccg
      361 gggatgaggc tgactattac tgtcaggtgt gggacagtag tagtaaatgg atattcggcg
      421 gggggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005037             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:21733:14830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005037
VERSION     KCWK01005037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:21733:14830"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70775.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          153 c          123 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccgcca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005038             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:22020:14826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005038
VERSION     KCWK01005038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:22020:14826"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70776.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          161 c          112 g          112 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggccgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005039             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:19700:5873
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005039
VERSION     KCWK01005039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19700:5873"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70777.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       412..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          162 c          125 g          107 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctcgtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac acagccgccc tcagtgtctg gggccccagg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatatatc ctggtaccag cagctcccag
      241 gaacggcccc caaactcctc gtctatgaca ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag ccaccctgac catcactggg ctccagactg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag tctgagtgct cgggtattcg
      421 gcggagggac ccggctaacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005040             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:12536:15211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005040
VERSION     KCWK01005040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12536:15211"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70778.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          163 c          110 g          114 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca cctttagcag tggcatcaat
      181 gttggtagtt acagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
      241 ctctactact actcagactc aagtaaacac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatgcaggc cttttactga tctctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccatatgg cacagcagcg cttcttactt cttcggtact
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005041             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14635:19816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005041
VERSION     KCWK01005041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14635:19816"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70779.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          140 c          134 g          102 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtgga ggagacaaca
      181 ttggaagtga agttgtcaac tggtaccagc agaagccacc gcaggcccct gtggtggtca
      241 tctatgctga ttatgaacgg ccctcaggca tccctgagcg attctctggc tccaaatcag
      301 ggaacatggc caccctgacc atcagcggag tcgaggccgg ggatgaggct gactattatt
      361 gtcaggtgtg ggacatttat attgaccatc cggtgttatt cggaggaggg acccgactga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005042             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:7316:10114
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005042
VERSION     KCWK01005042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7316:10114"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70780.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       409..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          160 c          124 g          107 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctcgtctcc tctcctcctc acccttttca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacaca gccgccctca gtgtctgggg ccccagggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaacatt ggaggttatt atatatcctg gtaccagcag ctcccaggaa
      241 cggcccccaa actcctcgtc tatgacaata ataagcgacc ctcaggggtt tctgaccgat
      301 tctctggctc caagtctggt tcctcagcca ccctgaccat cactgggctc cagactgagg
      361 atgaggctga ttattactgc cagtcctatg acagcagtct gagtgctcgg gtattcggcg
      421 gagggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005043             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:10713:21306
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005043
VERSION     KCWK01005043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:10713:21306"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..433
                     /note="immunoglobulin light chain variable region"
     V_region        104..433
     V_segment       104..397
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70781.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       402..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>472
                     /gene="IGLC"
BASE COUNT           94 a          158 c          115 g          105 t
ORIGIN      
        1 acatggggga cagaaggcag gactcaggat aatctccagc atggcctggt tccctctcgt
       61 cctcaccctc ctcactcact gtgcagttcc agggtcctgg gcccagtctg tgctgactca
      121 gccaccctca gcgtctggga ctcccgggca gagtgtcacc atctcgtgct ctggaagcag
      181 ctccaacatt ggaactaatt atgtatactg gtaccaacac ctcccaggaa cggcccccaa
      241 actcctcatc tattatagta atcagcgacc ctcaggggtc cctgcccgat tctctggctc
      301 taagtctggc acctcagcct ccctggccat cactggtctc cgatctgagg atgaggctga
      361 ttattactgt gcagcatggg ataacagcct gaccagtccg gtattcggag gagggacccg
      421 gctgaccgtc ctaagtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005044             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:16618:5538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005044
VERSION     KCWK01005044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16618:5538"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..455
                     /note="immunoglobulin light chain variable region"
     V_region        125..455
     V_segment       125..418
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70782.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       419..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           93 a          156 c          127 g          117 t
ORIGIN      
        1 acatgggggg gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct actcattcac ttcacagttc cagggtcctg
      121 ggcccagtct gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac
      181 catctcctgc actgggagca gctccaacat tggagattat tttgtgcagt ggtaccagca
      241 ccttccagga acggccccca aactcctcat ctatgaaaat aataagcgac cctcagggat
      301 ttctgatcga ttctctggct cccagtctgg aacctcagcc tccctgacca ttactggact
      361 ccagtctgag gatgaggctg attattactg ccagtcctat gacagtagtt tgattgctgt
      421 gttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01005045             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:24887:5101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005045
VERSION     KCWK01005045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24887:5101"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70783.1"
                     /translation="DYYCGAWDSSLSGYIF"
     J_segment       407..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          159 c          122 g          109 t
ORIGIN      
        1 acatggggct gcctcagctg tgagcacaga aggcaggact tgggacaatc ttcatcatga
       61 cctggtcccc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tcctgacgca gccgccctca gtgtctgcgg ccccagggca gaaggtcacc atctcctgct
      181 ctggaagtag ctccaacatc gggagaaatt ctgtctcctg gtaccagcag gtcccaggaa
      241 cggcccccaa actcctcacc tatgacaatg ataagcgacc ctcaggggtt tctgaccgat
      301 tctctggctc caagtctggt tcctcagcct ccctggccat cactggactc cagactggag
      361 atgaggctga ttattactgc ggagcatggg atagcagtct gagtggttac attttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01005046             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:21503:12296
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005046
VERSION     KCWK01005046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:21503:12296"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70784.1"
                     /translation="DYYCCSYRSGPTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           84 a          158 c          125 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt ataatggcgt ctcctggtac caacaacact cagggacagc
      241 ccccaaactc ctgatttatg atgtgaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggacga
      361 ggctgattat tactgctgct catataggag tggacccact tgggttttcg gcggagggac
      421 ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005047             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:14672:18038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005047
VERSION     KCWK01005047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:14672:18038"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..449
                     /note="immunoglobulin light chain variable region"
     V_region        116..449
     V_segment       116..412
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70785.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       419..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           85 a          167 c          133 g          102 t
ORIGIN      
        1 acatgggggc agtgtggctg cctcagcaga gccctgagga gtctgcacca tggcctggac
       61 cccaatcctc ctcctcctcc tcactctcct ccttcactgc acagggtctc tctcccagcc
      121 tgtggtgact cagtcgtcct ctgcctctgc ctccctggga gcctcggtca agctcacctg
      181 cactctgagc ggtgggcaca gcgactacac catcgcatgg catcagcagc agcaagggaa
      241 ggcccctcgg tatttgatgt ggcttaaaag tgatggcagc cacagcaagg gggacgggat
      301 ccctgatcgc ttctccggct ccagctccgg ggctgagcgc tacctcacca tctccaacct
      361 ccagtctgag gatgaggctg attattactg tcagacctgg gagactggca ttcaggtgtt
      421 cggcggaggg acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01005048             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:20930:3153
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005048
VERSION     KCWK01005048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20930:3153"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..262
                     /note="immunoglobulin light chain variable region"
     V_region        7..262
     V_segment       7..225
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>234
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70786.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       226..262
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        263..>300
                     /gene="IGLC"
BASE COUNT           62 a           93 c           81 g           64 t
ORIGIN      
        1 acatggggct accacataca ctggtaccag cagaagccag ggagtccccc ccggtatctt
       61 ctgagataca gatcagactc agataagggc cagggctctg gagtccccag ccggttctct
      121 ggatccaaag atgctgcagc gaacacaggg attttacgca tctctgggct ccagtctgag
      181 gatgaggctg actattactg tgccattggg cacagcagcg gtccttactt cttcggtgct
      241 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005049             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:16950:15470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005049
VERSION     KCWK01005049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16950:15470"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..343
                     /note="immunoglobulin light chain variable region"
     V_region        13..343
     V_segment       13..307
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70787.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       308..343
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>381
                     /gene="IGLC"
BASE COUNT           74 a          122 c           98 g           87 t
ORIGIN      
        1 acatgggggg ctcaggctgc cctgactcag cctcgctcag tgtctgggtc tcctggacag
       61 tcggtcacca tctcctgcac tggaaccagc agtgacatcg gtggttataa ctatgtctcc
      121 tggtaccaac agcatccagg cacagccccc aaagtcatga tttatgaggt cagtaagcgg
      181 ccctcagggg tctctgatcg cttctctggc tccaagtctg gcaacacggc ctccctgacc
      241 atctctgggc tccaggctga ggacgaggct gattattact gcagctcata tacaggcatc
      301 aacagttaca tcttcggtgg tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc
      361 cccacggtca ctctgttccc g
//
LOCUS       KCWK01005050             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:21677:14411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005050
VERSION     KCWK01005050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:21677:14411"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..387
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70788.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       391..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           86 a          154 c          120 g          102 t
ORIGIN      
        1 acatggggag gaagcagagc ctggagcatc tccaccatgg cctgggctcc actcctcctc
       61 accctcctcg ctcactgcac agggtcttgg gctgaggttg tgttcactca gccccattct
      121 gtgtcggggt ctccggggca gacggtcacc atctcctgca cccgcagcag tggcagcatt
      181 gacaacggct ttgtgtactg gtaccagcag cggccgggca gcgctcccac cactgtgatt
      241 tacaaagata accaaagacc ctctggggtc cctgatcggt tctctggctc catcgacagc
      301 tcctccaact ctgcctccct caccatctct ggactgaaat ctgaggacga ggctgactat
      361 tactgtcagt cttatgacag cagcagtgta ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005051             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:14349:3785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005051
VERSION     KCWK01005051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:14349:3785"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..430
                     /note="immunoglobulin light chain variable region"
     V_region        104..430
     V_segment       104..397
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70789.1"
                     /translation="DYHCSAGFGSGYSWQWVF"
     J_segment       398..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>472
                     /gene="IGLC"
BASE COUNT           93 a          150 c          131 g           98 t
ORIGIN      
        1 acatggggat cctggcttca gaagcagcat ctgggacatg tcagccatgg cctggacgcc
       61 tctcctcctc agcctcctcg ctcactgcac aggctctgtg gcctcctatg agctgactca
      121 gccaccctca gtgtcggtgt ccccaggaca gacagccagc atcacctgct ctggagataa
      181 attggggaat gtttatgctt attggtacca gcagaagcca ggccaggccc ctatactggt
      241 catctacaaa gatagcaacc ggccctcagg gatccctgac cgattctctg gctccaactc
      301 agggaacacg gccaccctga ccatcagcag ggtcgaggct ggggatgagg ccgactatca
      361 ctgttctgca ggctttggca gtgggtacag ctggcagtgg gttttcggcg gagggacccg
      421 gctaaccgtc gtaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005052             283 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:18536:14707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005052
VERSION     KCWK01005052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 283)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:18536:14707"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..245
                     /note="immunoglobulin light chain variable region"
     V_region        111..245
     V_segment       111..208
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <170..>217
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70790.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       209..245
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        246..>283
                     /gene="IGLC"
BASE COUNT           49 a           94 c           79 g           61 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgg
      121 cacgtcagcc tccctggcca tcagtgggct ccagaccgag gatgaggctg attattactg
      181 cgcagcgtgg gatgatagcc tgagcagtta catcttcgct gctgggaccc ggctcaccgt
      241 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005053             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12255:17636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005053
VERSION     KCWK01005053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12255:17636"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70791.1"
                     /translation="DYYCCSYTTDSTYIF"
     J_segment       400..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          162 c          114 g          109 t
ORIGIN      
        1 acatgggggg gggtctcaga aggcagcgct ctcaggacgt ctccaccatg gcctggactc
       61 tgctcctcgt caccctcctc actcaaggca caggatcctg ggctcagtct gccccgactc
      121 agcctccctc tgtgtctggg tctcctggac agtccgtcac catctcctgc actggaacca
      181 tcagtgacgt tggtggtcat aactctatct cctggtacca acaccaccca ggcaaacccc
      241 ccaaagtcat gacttatggt gtcagtaatc gggcctcagg ggtctctgac cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgttgttca tatacaaccg atagcactta catcttcggt agtgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005054             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:20189:17396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005054
VERSION     KCWK01005054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20189:17396"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70792.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       413..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           90 a          156 c          129 g          113 t
ORIGIN      
        1 acatgggggg agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccctct
      181 cctgcactgg gagcagctcc aacattggag attattatgt gcagtggtac cagcagcttc
      241 caggaacggc ccccaaactc ctcatctatg aaaataataa gcgaccctca ggggtttctg
      301 atcgattctc tggctcccag tctggtacct cagcctccct gaccatcact ggactccagt
      361 ctgacgatga ggctgattat tactgtcagt cctatgatag cagcctgagt gttgtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01005055             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:4367:18321
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005055
VERSION     KCWK01005055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:4367:18321"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70793.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          150 c          117 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacaggcac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005056             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:20389:17177
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005056
VERSION     KCWK01005056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20389:17177"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70794.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          151 c          121 g          113 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gttcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattata acgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 caaactcata atttttgacg tcattaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcgacacgg cctccctgac catctctggg ctccgggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag aaataatttt ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005057             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:16083:7586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005057
VERSION     KCWK01005057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16083:7586"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..230
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70795.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       232..269
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           63 a           90 c           79 g           75 t
ORIGIN      
        1 acatgggggg agcagctcca acattggagg ttattatgtg cagtggtacc agcagcttcc
       61 agggacggcc cccaaactcc tcatctatga aaatgataaa cgaccctcag gggtttctga
      121 tcgattctct ggctcccagt ctgattcctc agcctccctg accatcactg gactccagtc
      181 tgaggatgag gctgattatt actgccagtc ctatgacagc agcttgagtg ttgtgttatt
      241 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01005058             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:9125:15422
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005058
VERSION     KCWK01005058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9125:15422"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70796.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           82 a          164 c          123 g          102 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggc
      181 cactacagct acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggttcttg
      241 atgtggctta agagtgatgg cagccacacc aagggggacg gggtccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatatt ggcatttggg ttttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005059             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:26402:4591
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005059
VERSION     KCWK01005059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:26402:4591"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70797.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          161 c          122 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtaataaaaa catgtactgg taccaacaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaactaac acagcgtttt tggtcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtttgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01005060             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:15721:5986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005060
VERSION     KCWK01005060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15721:5986"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70798.1"
                     /translation="DINCHSADSSGNHCVF"
     J_segment       395..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          102 a          131 c          127 g          103 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgttctg gagaaatagt
      181 ggcaaaaaaa tatggtcagt ggttccagca gaagccaggg caggcccctg ttctggtgat
      241 atataaggac agtgagaggc cctcagggat ccctgagcga ttctctaggt ccatttcagg
      301 gacaacaatt accttgacca tctgtggggc cccggcagaa gatgaggctg acattaactg
      361 tcattcagca gacagcagtg gtaatcattg tgtcttcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005061             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:22078:18722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005061
VERSION     KCWK01005061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22078:18722"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..431
                     /note="immunoglobulin light chain variable region"
     V_region        107..431
     V_segment       107..394
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70799.1"
                     /translation="DYYCQVWDSSTRYAVF"
     J_segment       401..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          148 c          137 g           96 t
ORIGIN      
        1 acatggggct gtctgggtct caggaggcag cattgacggt gcctcagcca tggcctggac
       61 ccttctcctc ctcggcctcc tcgcttactg cacaggctct gcgacctcct atgagctgac
      121 tcagccaccc tcattgccag cggcctcagg acagacggcc aggatcgcct gtgggggaga
      181 cagcattgga agtgaaaatg tgttctggta ccagcagaag ccacggcagg cccctgtcct
      241 ggtcatctat ggtgatacga aacggccctc agggatccct gagcgattct ctggctccat
      301 ctctgggaac accgccaccc tgaccatcaa cagggtcgag gccggggatg aggctgacta
      361 ttactgtcag gtgtgggaca gtagtactag atacgcggtt ttcggcggag ggacccggct
      421 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005062             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10316:7987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005062
VERSION     KCWK01005062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10316:7987"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..266
                     /note="immunoglobulin light chain variable region"
     V_region        8..266
     V_segment       8..229
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70800.1"
                     /translation="DYSCQVWDSESDYYIF"
     J_segment       230..266
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           66 a           86 c           89 g           63 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaattaa atttgtccac tggtaccagc agaagccagc
       61 gcaggcccct gtgaaggtca tctatgctga tgacaaacgg ccctcaggga tccctgagag
      121 attctctggc tccaattcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      181 ggatgaggct gactattcct gtcaggtgtg ggacagtgag agtgattatt acatcttcgg
      241 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      301 cccg
//
LOCUS       KCWK01005063             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:26178:8643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005063
VERSION     KCWK01005063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:26178:8643"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70801.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          146 c          131 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcccagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gaactgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc agcagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgatagtaaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt ttgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005064             282 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:27363:19022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005064
VERSION     KCWK01005064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 282)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:27363:19022"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..244
                     /note="immunoglobulin light chain variable region"
     V_region        1..244
     V_segment       1..207
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <172..>216
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70802.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       208..244
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        245..>282
                     /gene="IGLC"
BASE COUNT           59 a           80 c           78 g           65 t
ORIGIN      
        1 acatgggctg gagatgtatt gccaaaaaaa tatgcttatt ggttccagca gaagccaggc
       61 cagtcccctg tattggtcat ctctgaggac accgaacggc cctctgggat ccctgagaga
      121 ttctctggct ccaccttgac tatcagtggg gcccaggtgg aggatgaagc tgactactac
      181 tgttactcag cagacagtag tggtcatggc ttcttcggag gagggacccg gctgaccgtc
      241 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005065             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:11171:6969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005065
VERSION     KCWK01005065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11171:6969"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70803.1"
                     /translation="DYYCQVWGMTSDHPVF"
     J_segment       396..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           92 a          140 c          138 g           94 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcatag acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgagtcagc
      121 caccctcggt gtcagtgtcc ccaggagaga cggccaggat cacctgtggg ggagacaaaa
      181 ttggaagtga agtagtgaat tggtaccagc agaagccacc gcaggcccct atactggtca
      241 tctatgctga taacgaacgg cccccaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg gggcatgact agtgatcatc cggttttcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005066             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:10323:19285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005066
VERSION     KCWK01005066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10323:19285"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..436
                     /note="immunoglobulin light chain variable region"
     V_region        110..436
     V_segment       110..401
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70804.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       403..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>478
                     /gene="IGLC"
BASE COUNT           85 a          151 c          132 g          110 t
ORIGIN      
        1 acatgggggg cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctctc cttctcactc tgctggttca ctgcacaggg tcctgggccc agtctgtgct
      121 gacgcagccg ccctcagcat ctggggcccc cgggcagagg gttaccatct cctgcactgg
      181 gagcagctcc aacatcgggg cgggttttta tgtgtcctgg taccagcagt tccctgggac
      241 agcccccaaa ctcctcatct ttgaaaataa taagcgaccc tcaggggttt ctgaccgatt
      301 ctctggctcc aagtctggtt cctcagcctc cctgaccatc actggactcc agtctgagga
      361 tgaggctgat tattactgct catcatggga aagcagcctg aattgggtat tcggcggagg
      421 gacccggctg accgtcttag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005067             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17606:17093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005067
VERSION     KCWK01005067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17606:17093"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70805.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          161 c          115 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 ctgcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatacaaatc agactcagat atggaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ctcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ctactgtgcc attgggcaca gcagcggtga ttacatcttc gctgctggga
      421 cccgcctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005068             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:14154:12574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005068
VERSION     KCWK01005068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14154:12574"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..403
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70806.1"
                     /translation="DYHCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          162 c          114 g          106 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagtcagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacacacac tggtaccaac agaagccagg gagtcccccc cggtatcttc
      241 tgaaatacaa atcagacaca gaccagggcc aggggtctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggta ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctatcactgt gccattggtc acagcagcgg tccatacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005069             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:8513:4436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005069
VERSION     KCWK01005069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8513:4436"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70807.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          148 c          131 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccgatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta agagtgtgca ctggtaccaa cacaagccac cgcaggcccc tatcctggtc
      241 atctattatt ataccgaacg gccctcggcg atccctgggc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacactac tattgatcat ggctttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005070             351 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:5218:15752
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005070
VERSION     KCWK01005070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 351)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5218:15752"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..313
                     /note="immunoglobulin light chain variable region"
     V_region        7..313
     V_segment       7..273
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <241..>285
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70808.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       276..313
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        314..>351
                     /gene="IGLC"
BASE COUNT           78 a          106 c           90 g           77 t
ORIGIN      
        1 acatggggaa catcagccag tctcacatgc accttcagcg gtggcatcaa tgttgctggc
       61 taccacatac actggtacca gcagaagcca gggagtcctc cccgatatct tctgagatac
      121 aaatcggact cagataaggg ccagggctct ggagtcccca gccgcttctc tggatccaaa
      181 gatgcttcag cgaacacagg gattttacgc atctctgggc tccagtctga ggatgaggct
      241 gactattact gtgccattgg acacagcagc ggtgattaca tcttcggtgc tgggacccgg
      301 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01005071             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:18633:17842
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005071
VERSION     KCWK01005071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18633:17842"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70809.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           81 a          157 c          127 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctccggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattat tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005072             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:6037:4472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005072
VERSION     KCWK01005072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:6037:4472"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70810.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       412..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          126 g          107 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctcgtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac acagccgccc tcagtgtctg gggccccagg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatatatc ctggtaccag cagctcccag
      241 gaacggcccc caaactcctc gtctatgaca ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag ccaccctgac catcactggg ctccagactg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag tctgagtgct cgggtattcg
      421 gcggggggac ccggctaacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005073             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:17259:9984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005073
VERSION     KCWK01005073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17259:9984"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..405
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70811.1"
                     /translation="DYYCQSFDSSTVLF"
     J_segment       411..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           82 a          161 c          129 g          111 t
ORIGIN      
        1 acatgggggc tcattcctgg ctgtggctca ggaagcagag cctggagcat ctccaccatg
       61 gcctgggctc cgctcctcct caccctcctc gctcactgca cagggtcttg ggctgaggtt
      121 gtgttcactc agccccaatc tgtgtcgggg tctccggggc agacggtcac catctcctgc
      181 acccgcagca gtggcagcat tggcaacagc tatgtgtact ggttccagca gcggccgggc
      241 agcgtcccca ctattgtgat ttacaaagat gaccaaagac cctctggggt ccctgatcgg
      301 ttctctggct ccatcgacag ctcctccaac tctgcctccc tcaccatctc tggactgaag
      361 tctggggacg aggctgacta ttactgtcag tcttttgaca gcagcactgt cttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01005074             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10275:4731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005074
VERSION     KCWK01005074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10275:4731"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    161..266
                     /note="immunoglobulin light chain variable region"
     V_region        161..266
     V_segment       161..231
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70812.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       236..266
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           49 a          106 c           81 g           68 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctctg ggctccagac
      181 tgaggatgag gctgattatt actgcagctc atatgcaggc agcaacgctt tattcttcgg
      241 acgagggacc cgcctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      301 cccg
//
LOCUS       KCWK01005075             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:23689:14412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005075
VERSION     KCWK01005075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23689:14412"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70813.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          163 c          112 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgttgccta ccacctccac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagttacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaaa tgcttcaaca aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccatcggac acagcagcgg tccttacatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005076             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:12539:14720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005076
VERSION     KCWK01005076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12539:14720"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70814.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       402..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          151 c          121 g          114 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggttcaggct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatgt tgggtattat aacgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 ccaaactcat gatttattac gtcattaagc ggccctcagg ggtttctgat cgcttctctg
      301 gctccaagtc tggcgacacg gcctccctga ccatctctgg gctccaggct gaggatgacg
      361 ctgattatta ctgcagctca tatgcaggca gaaataattt tttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005077             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:7019:18077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005077
VERSION     KCWK01005077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:7019:18077"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70815.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          147 c          131 g           97 t
ORIGIN      
        1 acatgggggt gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005078             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:18873:15155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005078
VERSION     KCWK01005078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:18873:15155"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..400
                     /note="immunoglobulin light chain variable region"
     V_region        79..400
     V_segment       79..364
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <328..>372
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70816.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       368..400
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        401..>438
                     /gene="IGLC"
BASE COUNT           89 a          138 c          122 g           89 t
ORIGIN      
        1 acatgggacg gtgcctcagc catggcctgg acccttctcc tcctcggcct cctcgcttac
       61 tgcacaggct ctgcgacctc ctatgaactg actcagtcac cctcagtgtc agcggcctca
      121 ggacagccgg ccaggatcac ctgtggggga gacaacattg gaattaaaac tgtacactgg
      181 taccagcaga agccaccgca gggccctgta ttggtcatct ttgctgatag taagcggccc
      241 tcagggatcc ctgagcgatt ctctggctcc aactcaggga acaccgccac cctgaccatc
      301 agcagggtcg aggccgggga tgaggctgac tattactgtc aggtgtggga cagtagtagt
      361 aaatggatat tcggcggggg gacccggcta accgtcctag gtcagcccaa ggctgccccc
      421 tcggtcactc tcttcccg
//
LOCUS       KCWK01005079             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:8829:6833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005079
VERSION     KCWK01005079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8829:6833"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..265
                     /note="immunoglobulin light chain variable region"
     V_region        1..265
     V_segment       1..228
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70817.1"
                     /translation="AYYCQVWDSDSDHYIF"
     J_segment       229..265
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           68 a           89 c           84 g           62 t
ORIGIN      
        1 acatgggggg gagacaacat tggaactaat tttgtgcact ggtaccagca gaagccagcg
       61 caggccccta tgcaggtcat ctatgctgat aacaaacggc cctcagggat ccctgagaga
      121 ttctctggct ccaactcagg gaacaccgcc accctgacca tcagcggagt cgaggccggg
      181 gatgaggctg cctattactg tcaggtgtgg gacagtgata gtgatcatta catcttcggt
      241 actgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      301 ccg
//
LOCUS       KCWK01005080             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16084:12863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005080
VERSION     KCWK01005080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16084:12863"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70818.1"
                     /translation="DYYCSSYAGRNTLLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          162 c          124 g          104 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tggactcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt atgattatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaactc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tccggcaaca cggcctccct gaccatctct gggctccagc ctgaggacga
      361 ggctgattat tactgcagct catatgcagg ccgcaacact ctcttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005081             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:8286:4846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005081
VERSION     KCWK01005081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8286:4846"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70819.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       399..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          153 c          123 g          103 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gataatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgagc tgactcagcc
      121 accctcagcg tctggggctc ccgggcagag tgtcaccatc tcctgctctg gaagcagctc
      181 caatattgga agtaattctg tatactggta ccagcagttc ccaggaacgg cccccaaact
      241 cctcatctat tatagtaatc agcgaccctc aggggtccct gaccgagtct ctggctctaa
      301 gtcgggcacc tcagcctccc tggccatcac tggtctccga tctgaggatg aggctgatta
      361 ttactgtgca gcatgggatg acagcctgag aagtccgcta ttcggcggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005082             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:10486:6644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005082
VERSION     KCWK01005082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10486:6644"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70820.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       408..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           89 a          152 c          127 g          112 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcgga gggtcacgat ctcctgcagt
      181 gggagcaact ccaacattgg atattattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccaaac tcctcatcta tgaaaataat aagcgaccct ctggggtttc tgatcgattc
      301 tctggctccc agtctggtac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca ctcctatgac agcagtttga gtggtgtctt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005083             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:19300:6102
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005083
VERSION     KCWK01005083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19300:6102"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70821.1"
                     /translation="DYYCSSYAGSNNFLF"
     J_segment       402..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           90 a          155 c          118 g          110 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcactaatat tggatattat aatgctgtgt cttggtacca acaccatcca ggcaaagccc
      241 ccagactcat gatttatgac gtcagtaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacaattt tttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005084             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:8160:2640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005084
VERSION     KCWK01005084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:8160:2640"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70822.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          148 c          131 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tccgatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaag agtgtgcact ggtaccagca caagccaccg caggccccta tcctggtcat
      241 ctattattat accgaccggc cctcggcgat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacactacta ttgatcatgg ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005085             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:6719:4805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005085
VERSION     KCWK01005085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6719:4805"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70823.1"
                     /translation="DYFCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          157 c          121 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaggccagg gagtcctccc cggtatcttc
      241 tgagatacaa gtcggactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattgggc acagcagcgg tgattacatc ttcggttctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005086             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:20037:13894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005086
VERSION     KCWK01005086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20037:13894"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..398
                     /note="immunoglobulin light chain variable region"
     V_region        122..398
     V_segment       122..362
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <324..>371
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70824.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       367..398
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>437
                     /gene="IGLC"
BASE COUNT           90 a          145 c          103 g           99 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagttcca gggtcctggg cccagtctgt gctgactcag
      121 ccaccatctc gtgctctgga agcagctcca acattggaac taattatgta tactggtacc
      181 aacacctccc aggaacggcc cccaaactcc tcatctatta tagtaatcag cgaccctcag
      241 gggtccctga ccgattctct ggctctaagt ctggcacctc agcctccctg gccatcactg
      301 gtctccgatc tgaggatgag gctgattatt actgtgcagc atgggataac agcctgacca
      361 gtccggtatt cggaggaggg acccggctga ccgtcctaag tcagcccaag gctgccccct
      421 cggtcactct cttcccg
//
LOCUS       KCWK01005087             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:16232:2168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005087
VERSION     KCWK01005087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16232:2168"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70825.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          155 c          119 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcagtggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcgtc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca tgggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 agctgattat tactgcagct catatgcagg cagcaacact ttattcttcg gacgagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005088             299 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:18688:18077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005088
VERSION     KCWK01005088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 299)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18688:18077"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..261
                     /note="immunoglobulin light chain variable region"
     V_region        5..261
     V_segment       5..224
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <186..>233
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70826.1"
                     /translation="DYTCQVWDSESDYYIF"
     J_segment       225..261
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        262..>299
                     /gene="IGLC"
BASE COUNT           67 a           85 c           85 g           62 t
ORIGIN      
        1 acatgggaga caacattgga attaaatttg tccactggta ccagcagaag ccagcgcagg
       61 cccctgtgaa ggtcatctat ggtgatgaca aacggccctc agggatccct gagagattct
      121 ctggctccaa ttcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg
      181 aggctgacta tacctgtcag gtgtgggaca gtgagagtga ttattacatc ttcggtgctg
      241 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005089             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:28334:13257
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005089
VERSION     KCWK01005089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:28334:13257"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70827.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          151 c          116 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctcc cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005090             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:17817:12217
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005090
VERSION     KCWK01005090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17817:12217"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..279
                     /note="immunoglobulin light chain variable region"
     V_region        8..279
     V_segment       8..243
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70828.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       244..279
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>317
                     /gene="IGLC"
BASE COUNT           75 a           89 c           92 g           61 t
ORIGIN      
        1 acatgggggc caggatcacc tgtggcggag acaacattgg aattaaaaat gtccactggt
       61 accagcagaa gccagcacag gcccctgtgg tagtcatcta tgctgataac aaacggccct
      121 cagggatccc tgagcgactc tctggctcca actcagggaa tattgccacc ctgaccatca
      181 gcagggtcga ggccggggat gaggcagact attactgtca ggtgtgggac agtagtagta
      241 aatgggtatt cggcggaggg acccggctaa ccgtcctagg tcagcccaag gctgccccct
      301 cggtcactct cttcccg
//
LOCUS       KCWK01005091             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:16423:4126
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005091
VERSION     KCWK01005091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16423:4126"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70829.1"
                     /translation="VYYCQVWDSSSEWVF"
     J_segment       388..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           90 a          145 c          135 g           92 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcag tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaaggcag cacaggcccc tatgctggtc
      241 atctttgctg atagcaaacg gccctcaggg atccctgacc gattctctgg ctccaactca
      301 gggaacaccg gcaccctgac catcagcggg gtcgaggccg gggatgaggc tgtctattac
      361 tgtcaggtgt gggacagtag tagtgagtgg gttttcggcg gagggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005092             409 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:24447:12000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005092
VERSION     KCWK01005092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 409)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 409)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24447:12000"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..368
                     /note="immunoglobulin light chain variable region"
     V_region        97..368
     V_segment       97..334
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <296..>343
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70830.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       337..368
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        369..>409
                     /gene="IGLC"
BASE COUNT           79 a          124 c          122 g           84 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc aggatcacct gtgggggaga
      121 caacattgga ggtgaagttg tgaactggta ccagcagaag ccaccgcagg cccctgtcct
      181 ggtcatctat gctaataacg aacggccctc agggatccct gagcgattct ctggctccaa
      241 atcagggaac acggccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      301 ttactgtcag gtgtggggcg ttactagtga tcatccctta ttcggaggag ggacccggct
      361 gaccgtccaa ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005093             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:4856:17724
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005093
VERSION     KCWK01005093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4856:17724"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70831.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          138 c          136 g          102 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggagg agacaacatt
      181 ggaagtgaag ttgtcaactg gtaccagcag aggccaccgc aggcccctgt ggtggtcatc
      241 tatgctgatt atgaacggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacacggcca ccctgaccat cagcggagtc gaggccgggg atgaggctga ctattattgt
      361 caggtgtggg acatttatat tgaccatccg gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005094             382 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:10154:3143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005094
VERSION     KCWK01005094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 382)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10154:3143"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..344
                     /note="immunoglobulin light chain variable region"
     V_region        23..344
     V_segment       23..308
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <272..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70832.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       312..344
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>382
                     /gene="IGLC"
BASE COUNT           84 a          112 c          110 g           76 t
ORIGIN      
        1 acatgggaca ggctctgcga cctcctatga attgactcag tcaccctcag tgtcagcggc
       61 ctcaggacag ccggccagga tcacctgtgg gggagacaac attggaacta aaactgtgca
      121 ctggtaccaa cagaagccac cgcagggccc tgtattggtc atctttgctg atagtagacg
      181 gccctcaggg atccctgagc gattctctgg ctccaattca gggaacaccg ccaccctgac
      241 catcagcagg gtcgaggccg gggatgaggc tgactattac tgtcaggtgt gggacagtag
      301 tagtaaatgg atattcggcg gggggacccg gctaaccgtc ctaggtcagc ccaaggctgc
      361 cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005095             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:8618:13541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005095
VERSION     KCWK01005095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8618:13541"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..391
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70833.1"
                     /translation="DYYCQSFDSSTVLF"
     J_segment       397..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           81 a          156 c          126 g          106 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcatctcc accatggcct gggctccgct
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccaatctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagcattggc aacagctatg tgtactggtt ccagcagcgg ccgggcagcg tccccactat
      241 tgtgatttac aaagatgacc aaagaccctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctgga ctgaagtctg gggacgaggc
      361 tgactattac tgtcagtctt ttgacagcag cactgtctta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005096             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:5875:12065
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005096
VERSION     KCWK01005096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5875:12065"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70834.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           91 a          152 c          122 g          104 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaacag tgtcgccatc tcctgttctg gaagcagctc
      181 caacatcgga agtcatagtg tatcctggta ccagcagctc ccaggaacag ctcccaaact
      241 cctcatctat tatgatgatc aacgagcctc aggtgtctct gaccgattct ctggctccag
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcatgggatg atagcctgag aggttacatc ttcggtgatg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005097             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:24747:12832
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005097
VERSION     KCWK01005097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24747:12832"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..264
                     /note="immunoglobulin light chain variable region"
     V_region        7..264
     V_segment       7..227
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70835.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       228..264
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>302
                     /gene="IGLC"
BASE COUNT           59 a           96 c           78 g           69 t
ORIGIN      
        1 acatgggcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcag ctcccaggaa
       61 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      121 tctctggctc tcagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      181 atgaggctga ttattactgc gcagcatggg atgatagcct gagcggttac atcttcggtg
      241 gtgggacccg gctcgccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      301 cg
//
LOCUS       KCWK01005098             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:17798:14239
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005098
VERSION     KCWK01005098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17798:14239"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70836.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          157 c          126 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtc cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaggca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctggccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaagactt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005099             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:12494:16431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005099
VERSION     KCWK01005099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12494:16431"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70837.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       404..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          153 c          118 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcttc tcctggagca tcagccagac tcacctgcac cttgagcagt ggcatcagtg
      181 ttggtactta caggatattc tggtaccagc agaggccagg gagtcctccc cggtatcttc
      241 tgaaccacca cacagactca gataaacatc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttgctcat ctctgggctc cagtctgagg
      361 atggggctga ctattactgt atgatttggc acaacaatgc ttatgtgtta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005100             437 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:10032:7426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005100
VERSION     KCWK01005100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 437)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10032:7426"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    69..399
                     /note="immunoglobulin light chain variable region"
     V_region        69..399
     V_segment       69..355
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <327..>371
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70838.1"
                     /translation="DYYCSSYAGSNNFLF"
     J_segment       366..399
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        400..>437
                     /gene="IGLC"
BASE COUNT           84 a          145 c          105 g          103 t
ORIGIN      
        1 acatgggcac catggtctgg gctctgctcc tcctcaccct cctcactcag ggcacaggat
       61 cctgggctca ggctgccccg actcagcctc cctctgtgtc cgggtctcct ggacagtcgg
      121 tcaccatctc ctgcactgga accagcacta atattggata ttataatgct gtgtcttggt
      181 accaacacca tccaggcaaa gcccccagac tcatgattta tgacgtcagt aagcggccct
      241 caggggtctc tgatcgcttc tctggctcca agtctggcaa cacggcctcc ctgaccatct
      301 ctgggctcca gactgaggat gaggctgatt attactgcag ctcatatgca ggcagcaaca
      361 attttttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct
      421 cggtcactct cttcccg
//
LOCUS       KCWK01005101             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:23845:19621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005101
VERSION     KCWK01005101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23845:19621"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70839.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          156 c          119 g          110 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcat tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcacc tccaacatcg gaagcaataa tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctctttt attataatga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctcttgctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgataacctg agcggctaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01005102             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:15245:20056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005102
VERSION     KCWK01005102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15245:20056"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70840.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          156 c          123 g          103 t
ORIGIN      
        1 acatgggggg gctcaggaag cagagcctgg agcatctcca ccatggcctg ggctccactc
       61 ctcctcaccc tcctcgctca ctgcacaggg tcttgggctg aggttgtgtt cactcagccc
      121 cattctgtgt cggggtctcc ggggcagacg gtcaccatct cctgcacccg cagcagtggc
      181 agcattgaca acggctttgt gtactggtac cagcagcggc cgggcagcgc tcccaccact
      241 gtgatttaca aagataacca aagaccctct ggggtccctg atcggttctc tggctccatc
      301 gacagctcct ccaactctgc ctccctcacc atctctggac tgaaatctga ggacgaggct
      361 gactattact gtcagtctta tgacagcagc agtgtattat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005103             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:6807:4997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005103
VERSION     KCWK01005103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:6807:4997"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70841.1"
                     /translation="AYYCQVWDSDSDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          147 c          130 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gactctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaaggcag cgcaggcccc tatgcaggtc
      241 atgtatgctg ataacaaacg gccctcaggg atccctgaga gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctattac
      361 tgtcaggtgt gggacagtga tagtgatcat tacatcttcg gtactgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005104             305 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:24296:3808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005104
VERSION     KCWK01005104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 305)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:24296:3808"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..267
                     /note="immunoglobulin light chain variable region"
     V_region        7..267
     V_segment       7..228
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <198..>239
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70842.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       230..267
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        268..>305
                     /gene="IGLC"
BASE COUNT           69 a           85 c           82 g           69 t
ORIGIN      
        1 acatgggtgt tggaagtaaa aacatgtact ggtaccagca gaagccaggg agcgctccca
       61 ggttattcct gtactactac tccgactcag acaagcaact gggacctggg gtccccaatc
      121 gagtctctgg ctccaaggag acctcaagta acacagcgtt tttgctcatc tctgggctcc
      181 agcctgagga cgaggccgat tattactgtc agatgtatga cagtagtgat gtgttattcg
      241 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      301 tcccg
//
LOCUS       KCWK01005105             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:15483:21588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005105
VERSION     KCWK01005105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15483:21588"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70843.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          155 c          120 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatgtt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg cttcagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacgcttta ttcttcggac gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005106             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:7623:3664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005106
VERSION     KCWK01005106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7623:3664"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70844.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>460
                     /gene="IGLC"
BASE COUNT           95 a          143 c          124 g           98 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaagatc acctgctctg gagatgcact
      181 gccaaaaaaa aatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 cgatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005107             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:10985:18202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005107
VERSION     KCWK01005107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10985:18202"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70845.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          162 c          109 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005108             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:16218:7923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005108
VERSION     KCWK01005108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16218:7923"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70846.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          154 c          127 g          112 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc atctcctgca
      181 ctgggagcga ctccaacatt ggaggttatt atgtgcagtg gtaccagcag cttccaggaa
      241 cggcccccaa actcctcatc tatgaaaatg ataaacgacc ctcaggggtt tctgatcgat
      301 tctctggctc ccagtctgat tcctcagcct ccctgaccat cactggactc cagtctgagg
      361 atgaggctga ttattactgc cagtcctatg acagcagctt gagtgttgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005109             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:11265:4211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005109
VERSION     KCWK01005109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11265:4211"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..392
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70847.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       394..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          155 c          114 g          106 t
ORIGIN      
        1 acatgggggg tacagaaggc aggactcagg acaatctcca gcatggcctg gttccctctc
       61 gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc agtctgtgct gactcagcct
      121 ccctcagcgt ctgaggccgc caggaagagt gtcaccatct cctgttctgg aagcacctcc
      181 aacatcggaa gcaataatgt atcctggtac cagcagctcc caggaacagc tcccaaactc
      241 ctcttttatt ataatgatca acgagcctca ggtgtctctg accgattctc ttgctccaag
      301 tctggcacgt cagcctccct ggccatcagt gggctccaga ccgaggatga ggctgattat
      361 tactgcgcat catgggatga taccctgagc ggctacatct tcggtgctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01005110             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:11329:21429
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005110
VERSION     KCWK01005110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:11329:21429"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70848.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          163 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctata ctactactcc gactcagaca agcagctggg ccctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005111             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:23258:7328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005111
VERSION     KCWK01005111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23258:7328"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70849.1"
                     /translation="DHYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          162 c          111 g          110 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacca ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005112             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:14453:10869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005112
VERSION     KCWK01005112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:14453:10869"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70850.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       414..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           98 a          158 c          125 g          107 t
ORIGIN      
        1 acatggggga agcgcagctt cagctgtggg tacagaaggc aggactcagg acaatctcca
       61 gcatggcctg gttccctctc gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc
      121 agtctgtgct gactcagact ccctcagcgt ctgaggccgc cagaaagatt gtcaccatct
      181 cctgttctgg aagcagctcc aacatcggaa gaaatagtgt atcctggtac cagcagctcc
      241 caggaacagc tcccaaactc ctcatctatt atagtgatca acgagcctca ggtgtctctg
      301 accgattctc tggctccaag tctggcacgt cagcctccct ggccatcagc gggctccagg
      361 ccgacgatga ggctgattat tactgcgcag catgggatga tagcctgagc ggttacatct
      421 tcggtgctgg gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCWK01005113             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:20285:18968
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005113
VERSION     KCWK01005113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20285:18968"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..336
                     /note="immunoglobulin light chain variable region"
     V_region        12..336
     V_segment       12..298
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <261..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70851.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       300..336
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           79 a          116 c          105 g           74 t
ORIGIN      
        1 acatgggggc ctcctatgat ctgactcagc caccctcggt gtcagtgtcc ccaggacaga
       61 cggccaggat cacctgtggg ggagacaaca ttggaagtca aagtgtgcac tggtaccagc
      121 acaagccacc gcaggcccct gttctggtca tcttttatta taccgaacgg ccctcaggaa
      181 tccctgagcg aatctctggc tccaaatcag ggaacaccgc caccctgacc atcagcgggg
      241 tcgaggccgg ggatgaggct gactattact gtcaggtgtg ggacacaagt cttgatcacg
      301 gcttattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      361 tcactctctt cccg
//
LOCUS       KCWK01005114             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:16677:8867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005114
VERSION     KCWK01005114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:16677:8867"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70852.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       391..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          139 c          137 g          101 t
ORIGIN      
        1 acatgggggg actttgggaa gcagccttgg cggtgcctca gccatggccg ggacccttct
       61 cctcctcggc ctccttgctc actttacagg ctctgtggcc tcctatgagt tgcctcagcc
      121 acgctcagtg tccgtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaat agtgtgcatt ggtaccagca gaagccaccg cgggcccctg tattggtcat
      241 ctctgttgat agcgaacggc cctcagggat ccctgagcga ttctctggtt ccagatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gataatattt ataaatacgc ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005115             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22148:13098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005115
VERSION     KCWK01005115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22148:13098"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70853.1"
                     /translation="DYFCQVWDLNSHHLLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           85 a          147 c          136 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gactctgcgg cctcctatga tctgacgcag
      121 ccaccctcga tttcagtgtc cccaggacag acggccaggc tgacctgcgg gggagacaac
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atctatgctg acagcgcgcg gccctcaggg atccctgagc gattctctgg ctccaagtca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactatttc
      361 tgtcaggtgt gggaccttaa cagtcatcat ctcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005116             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:27110:13489
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005116
VERSION     KCWK01005116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:27110:13489"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70854.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          144 c          130 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga attgactcag
      121 tcaccctcag tgtcagcgtc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tctattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005117             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:17258:12647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005117
VERSION     KCWK01005117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17258:12647"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..258
                     /note="immunoglobulin light chain variable region"
     V_region        8..258
     V_segment       8..221
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <177..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70855.1"
                     /translation="DYFCAAAYGSGSSWQWVF"
     J_segment       222..258
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           58 a           88 c           91 g           59 t
ORIGIN      
        1 acatgggggg gaatgtatat gcttactggt tccagcagaa gccaggccag gcccctgtag
       61 tggtcatcta caaagatacc aaccggccct cagggatccc tgagcgattc tctggctccg
      121 actcagggaa cacggccacc ctgaccatca gcagggtcga ggctggggat gaggccgact
      181 atttttgtgc tgcagcctat ggcagtggca gcagctggca gtgggtattc ggcggaggga
      241 cccggctaat cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005118             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:19663:17057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005118
VERSION     KCWK01005118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19663:17057"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..437
                     /note="immunoglobulin light chain variable region"
     V_region        92..437
     V_segment       92..400
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70856.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       401..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           93 a          161 c          110 g          111 t
ORIGIN      
        1 acatgggact gcagggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc ccagcctgtg ctgacccagc caacctccct
      121 ctcagcatct ccgggagcat cagccagact cagctgcacc ttgagcagtg gcaatgttgg
      181 tagttacagc atattctggt accagcagaa gccagggagt cctccccggt accttcttta
      241 ctactactca gactcaagta accaccagga ctctggagtc cccagccgct tctctggatc
      301 gaaagatgct tcagccaatg cagggctttt actgatctct gggctccagt ctgaagatga
      361 ggctgactat tactgtgcca catggcacag cagcgcttct tacatcttcg gtgctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005119             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:7246:11641
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005119
VERSION     KCWK01005119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7246:11641"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70857.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       415..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          155 c          128 g          113 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcgctggga gcagctccaa cattggagat tattatgtgc agtggtacca gcagcttcca
      241 ggaacggccc ccaaactcct catctatgaa aatcataagc gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagta gtttgagtgc tgtattattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01005120             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:11967:2908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005120
VERSION     KCWK01005120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:11967:2908"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..433
                     /note="immunoglobulin light chain variable region"
     V_region        88..433
     V_segment       88..396
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70858.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           93 a          157 c          112 g          109 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttga gcagtggcaa tgttggtagt
      181 tacagcatat tctggtacca gcagaagcca gggagtcctc cccggtacct tctttactac
      241 tactcagact caagtaacca ccaggactct ggagtcccca gccgcttctc tggatcgaaa
      301 gatgtttcag ccaatgcagg acttttactg atctctgggc tccagtctga agatgaggct
      361 gactattact gtgccacatg gcacagcagc gcttcttaca tcttcggggg ggggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01005121             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:22468:10582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005121
VERSION     KCWK01005121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22468:10582"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70859.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          148 c          128 g           98 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtacac tggtaccagc acaagccacc gcaggcccct gttctgctca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttgttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005122             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:7835:8341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005122
VERSION     KCWK01005122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7835:8341"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70860.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       398..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          165 c          124 g          100 t
ORIGIN      
        1 acatggggga gcagagccct gaggagtctg caccatggcc tggaccccaa tcctcctcct
       61 cctcctcact ctcctccttc actgcacagg gtctctctcc cagcctgtgc tgactcagtc
      121 gccctctgcc tctgcctccc tgggagcctc ggtcaagctc acctgcactc tgagcagtgg
      181 ccactacagc tacaccatcg catggcatca gcagcaacaa gggaaggccc ctcggttctt
      241 gatgtggctt aagagtgatg gcagccacac caagggggac ggggtccctg atcgcttctc
      301 aggctccagc tccggggctg agcgctacct caccatctcc aacctccggt ctgaggatga
      361 ggctgattat tactgtcaga cctgggacat tggcatttgg gtattcggcg gagggacccg
      421 gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005123             340 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:14635:20396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005123
VERSION     KCWK01005123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 340)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14635:20396"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..302
                     /note="immunoglobulin light chain variable region"
     V_region        11..302
     V_segment       11..264
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <227..>274
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70861.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       266..302
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        303..>340
                     /gene="IGLC"
BASE COUNT           75 a          102 c           96 g           67 t
ORIGIN      
        1 acatggggca gtgtccccag gacagacggc caggatcacc tgtgggggag acaacattgg
       61 aagtcaaagt gtgcactggt accagcacaa gccaccgcag gcccctgtac tggtcatctt
      121 ttattatacc gaacggccct caggaatccc tgagcgattc tctggctcca aatcagggaa
      181 taccgccacc ctgaccatca gcggggtcga ggccggggat gaggctgact attactgtca
      241 ggtttgggac acaactattg atcacggctt attcggagga gggacccggc tgaccgtcct
      301 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005124             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:18622:19681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005124
VERSION     KCWK01005124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:18622:19681"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70862.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           88 a          157 c          126 g          110 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccgggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcgccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01005125             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:22016:10009
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005125
VERSION     KCWK01005125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:22016:10009"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..390
                     /gene="IGLV7-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70863.1"
                     /translation="EYYCWLYYSGAWVF"
     J_segment       391..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          156 c          122 g          100 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat accagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcactga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagttctgga
      181 gcagtcacca gtggtcacag tccacactgg ttccagcaga aacccggaca agcccccaag
      241 acactgattt atgatacaag caacacgctc tcctggaccc ctgcccggtt ctcaggctcc
      301 cttgctgggg gtaaagctgc cctgacactt tcggatgcgc agcccgagga cgaggctgag
      361 tattactgct ggctgtacta cagtggtgct tgggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005126             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:14440:6428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005126
VERSION     KCWK01005126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14440:6428"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70864.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          163 c          120 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactattcc gactcagaca agcagctggg acctggggtc ccccatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattac tactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005127             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:11613:15962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005127
VERSION     KCWK01005127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:11613:15962"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..394
                     /note="immunoglobulin light chain variable region"
     V_region        76..394
     V_segment       76..362
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70865.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       363..394
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>432
                     /gene="IGLC"
BASE COUNT           89 a          133 c          114 g           96 t
ORIGIN      
        1 acatggggtg tctccaccat ggcctggact cctctctggc tcaccctcct cagtctttgc
       61 acaggttctg tggtttcttc tgagctgact caggaccctg cagtgtctgt ggccttggga
      121 cagacagtca ggatcacctg ccaaggagac agcctcagaa gttattatgc aagttggtac
      181 cagcagaagc caggccaggc ccctatactg atcgtctatg gtaacaatta ccggccctca
      241 gggatcccag agcgattctc tggctccagt acacgaaaca cagcttcctt gaccatcact
      301 ggggctcagg tggaagatga ggctgactat tactgtgact cctgggacag ccgcggaacc
      361 caattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      421 actctcttcc cg
//
LOCUS       KCWK01005128             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22046:6301
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005128
VERSION     KCWK01005128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22046:6301"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70866.1"
                     /translation="DYYCAIWSSSAYIF"
     J_segment       403..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           86 a          157 c          116 g          117 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctgt cacagcctgt gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagtcagac tcacctgcac cttgcgcact ggcctcaatg
      181 ttggtggcta ctacatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgaattacta ctcagactca aatcagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgtttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccatttggt ccagcagcgc ttacatcttc ggtggtggga
      421 cccgactcaa cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005129             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15198:8936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005129
VERSION     KCWK01005129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15198:8936"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..425
                     /note="immunoglobulin light chain variable region"
     V_region        103..425
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70867.1"
                     /translation="HYYCQVWDISSEHVLF"
     J_segment       394..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>465
                     /gene="IGLC"
BASE COUNT           83 a          145 c          136 g          101 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gcctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 gttggaggtg atgttgtgaa ttggtaccac cagaagccac cgcaggcccc tgtcctggtc
      241 atccatgctg ataccgatcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccacccttac catcagcggg gtcgaggccg gggatgaggc tcactattac
      361 tgtcaggtgt gggacattag tagtgagcat gttttattcg gaggagggac ccggctgacc
      421 gtcctgggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005130             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14586:2453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005130
VERSION     KCWK01005130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14586:2453"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70868.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          148 c          129 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtacact ggtaccagca caagccaccg caggcccctg ttctgctcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaagcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttgttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005131             412 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14328:4455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005131
VERSION     KCWK01005131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14328:4455"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..372
                     /note="immunoglobulin light chain variable region"
     V_region        99..372
     V_segment       99..342
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>346
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70869.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       343..372
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        373..>412
                     /gene="IGLC"
BASE COUNT           83 a          130 c          109 g           90 t
ORIGIN      
        1 tcagaagcag agctctgggg tgtctccacc atggcctgga ctcctctctg gctcaccctc
       61 ctcagtcttt gcacaggttc tatggtttct tctgagctga cagacagtca ggattacctg
      121 ccaaggagac agcctcagaa gctcttatgc aagctggtac caacagaggc caggccaggc
      181 ccctgtgctg gtcgtctatg gtaacaacta ccggccctca gggatcccag agcgattctc
      241 tggctcctac tcacgaaaca cagcttcctt gaccatctct ggggctcagg tggaagatga
      301 ggctgactat tactgtgact cctgggacag cagcggaacc caattcggag gagggacccg
      361 gctgaccgtc ctgggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005132             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:10986:12325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005132
VERSION     KCWK01005132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:10986:12325"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    36..381
                     /note="immunoglobulin light chain variable region"
     V_region        36..381
     V_segment       36..342
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <312..>353
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70870.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       344..381
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        382..>419
                     /gene="IGLC"
BASE COUNT           80 a          138 c          106 g           95 t
ORIGIN      
        1 acatgggcct ctctcactgc acaggttccc tctcccagcc tgtgctgact cagccaccct
       61 ccctgtctgc atccccggga gcatcggcca gactcccctg caccctgagc agtgacctca
      121 gtgttggtag taaaaacatg tactggtacc agcagaagcc agggagcgct cccaggttat
      181 tcctgtacta ctactccgac tcagacaagc agctgggacc tggggtcccc aatcgagtct
      241 ctggctccaa ggagacctca agtaacacag cgtttttgct catctctggg ctccagcctg
      301 aggacgaggc cgattatttc tgccaggtgt ttgacagtag tgttgtgttc ttcggaggag
      361 ggacccgact gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005133             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:13270:19512
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005133
VERSION     KCWK01005133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13270:19512"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70871.1"
                     /translation="DYYCAIGHFSGNYIF"
     J_segment       402..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           92 a          157 c          116 g          112 t
ORIGIN      
        1 acatgggggg tggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc aagcctatgc tgactcagcc ggcctccctc
      121 tcagcatctc ctggagcatc tgccagtctc acatgcacct tcagcggtgg catcaatgtt
      181 gctggctacc acatacactg gtaccagcag aagccaggga gtcctccccg gtatcttctg
      241 agataccaat cagagtcaga tcacggccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcagcgaa cacagggatt ttacgcatct ctggactcca gtctgaggat
      361 gaggctgact attactgtgc cattgggcac ttcagcggta attacatatt cggtgctggg
      421 acccgtctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01005134             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10591:4451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005134
VERSION     KCWK01005134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10591:4451"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70872.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       385..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           98 a          143 c          119 g           98 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgccccca ggacagacgg ccaggatcac ctgctctgga gaagaattgc
      181 caaaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtc cagatcatct
      241 atgaggacag taaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc actggggccc aggtggaaga tgaagttgac tactactgct
      361 tctcaacaga caccagtggt aatcgggtat tcggcggagg gacccgtcta atcgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005135             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:16596:5339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005135
VERSION     KCWK01005135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16596:5339"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..396
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70873.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       397..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           91 a          152 c          118 g          110 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactt cacagttcca gggtcctggg cccagtctgt gctgacgcag
      121 ccgccctcag tgtctggggc gcccgggcag agggtcacca tctcctgcac tgggagcagc
      181 tccaacattg gagattattt tgtgcagtgg taccagcacc ttccaggaac ggcccccaaa
      241 ctcctcatct atgaaaataa taagcgaccc tcagggattt ctgatcgatt ctctggctcc
      301 cagtctggaa cctcagcctc cctgaccatc actggactcc agtctgagga tgaggctgat
      361 tattactgcc agtcctatga cagcagtttg attgctgtgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005136             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:20379:14015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005136
VERSION     KCWK01005136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20379:14015"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70874.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          128 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgatgccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005137             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:13512:3502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005137
VERSION     KCWK01005137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13512:3502"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70875.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          147 c          133 g           97 t
ORIGIN      
        1 acatgggggg gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccgatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta agagtgtgca ctggtaccag cacaagccac cgcaggcccc tatcctggtc
      241 atctattatt ataccgaacg gccctcggcg atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacactac tattgatcat ggctttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005138             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:8736:6698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005138
VERSION     KCWK01005138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8736:6698"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70876.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          143 c          142 g           92 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tggaagtgaa gttgtgaact ggtaccagcg gaagccagcg caggcccctg tgctggtcat
      241 ctatgctgat agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg ggtgaggctg actattactg
      361 tcaggtgtgg gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005139             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:23157:13537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005139
VERSION     KCWK01005139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23157:13537"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70877.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          152 c          122 g          114 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggttcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt ataacgctgt gtcttggtac caacagcatc caggcaaagc
      241 ccccaaactc ataatttttg acgtcattaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccggg ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagaaataat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005140             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:21815:1955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005140
VERSION     KCWK01005140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21815:1955"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70878.1"
                     /translation="DYYCQVWDISIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          143 c          133 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagc ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccagggtc acctgtggag gagacaacct
      181 tggatatgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctaaccga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacattagta ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005141             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:6833:19987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005141
VERSION     KCWK01005141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6833:19987"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..400
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70879.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           88 a          152 c          127 g          110 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctgcttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg tcaccatctc ctgctctggg
      181 agcagctcca acatcggggc gggtttttat gtatcctggt accagcagtt cccaggaaca
      241 gcccccaaac tcctcatctt tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggttc ctcagcctcc ctgaccatca ctggactcca atctgaggat
      361 gaggctgatt attattgttc atcatgggaa agcagcctga attgggtatt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005142             322 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:18979:13907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005142
VERSION     KCWK01005142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 322)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:18979:13907"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..284
                     /note="immunoglobulin light chain variable region"
     V_region        5..284
     V_segment       5..248
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <212..>256
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70880.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       252..284
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        285..>322
                     /gene="IGLC"
BASE COUNT           71 a           92 c           96 g           63 t
ORIGIN      
        1 acatgggcag ccggccagga tcacctgtgg gggagacaac attggaatta aaactgtaca
       61 ctggtaccag cagaagccac cgcagggccc tgtattggtc atctttgctg atagtaagcg
      121 gccctcaggg atccctgagc gattctctgg ctccaactca gggaacaccg ccaccctgac
      181 catcagcagg gtcgaggccg gggatgaggc tgactattac tgtcaggtgt gggacagtag
      241 tagtaaatgg atattcggcg gggggacccg gctaaccgtc ctaggtcagc ccaaggctgc
      301 cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005143             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:7942:7205
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005143
VERSION     KCWK01005143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:7942:7205"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..394
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70881.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       396..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           88 a          150 c          125 g          108 t
ORIGIN      
        1 acatgggggt gggcacagga ggcagcactc aggacagtct ccagcatggc ctggtctcct
       61 ctcctcctca cccttctcat tcactgcaca gggtcctggg cccagtctgt gctgacgcag
      121 ccgccctcag tgtctggggc gcccgggcag agggtcacca tctcctgcac tgggagcagc
      181 tccaacattg gaggttatta tgtgcagtgg taccagcagc ttccaggaac ggcccccaaa
      241 ctcctcatct atgaaaatga taaacgaccc tcaggggttt ctgatcgatt ctctggctcc
      301 cagtctgatt cctcagcctc cctgaccatc actggactcc agtctgagga tgaggctgat
      361 tattactgcc agtcctatga cagcagcttg agtgttgtgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005144             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:14874:16969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005144
VERSION     KCWK01005144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14874:16969"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..387
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70882.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       388..419
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           90 a          141 c          126 g          100 t
ORIGIN      
        1 acatggggtg ggctcagaag cagagctctg gggtgtctcc accatggcct ggactcctct
       61 ctggctcacc ctcctcagtc tttgcacagg ttctatggtt tcttctgagc tgactcagga
      121 ccctgcagtg tctgtggcct tggggcagac agtcaggatt acctgccaag gagacagcct
      181 cagaagctct tatgcaaact ggtaccaaca gaggccaggc caggcccctg tgctggttgt
      241 ctatggtaac aactaccggc cctcagggat cccagagcga ttctctggct cctactcccg
      301 aaacacagct tccttgacca tcactggggc tcaggtggaa gatgaggctg actattactg
      361 tgactcctgg gacagcagcg gaacccaatt cggaggaggg acccggctga ccgtcctagg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005145             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:24841:10514
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005145
VERSION     KCWK01005145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24841:10514"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70883.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          155 c          111 g          117 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcttc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttgctaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005146             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:2872:9342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005146
VERSION     KCWK01005146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:2872:9342"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..248
                     /note="immunoglobulin light chain variable region"
     V_region        8..248
     V_segment       8..212
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>220
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70884.1"
                     /translation="DYYCQVWDSDSKWIF"
     J_segment       216..248
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        249..>286
                     /gene="IGLC"
BASE COUNT           63 a           83 c           84 g           56 t
ORIGIN      
        1 acatggggga actaaaaatg tgcactggta ccagcagaag ccagcgcagg gccctgtatt
       61 ggtcatgttt gctgatacca gacggccctc agggatccct gaccgattct ctggctccaa
      121 ctcagggaac accgccaccc tgaccatcag cagggtcgag gccggggatg aggctgacta
      181 ttactgtcag gtgtgggaca gtgatagtaa atggatattc ggcggaggga cccggctaac
      241 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005147             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:17948:17065
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005147
VERSION     KCWK01005147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17948:17065"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70885.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          139 c          135 g          103 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtctt
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005148             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:22817:18312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005148
VERSION     KCWK01005148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22817:18312"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70886.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          143 c          136 g           99 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcga tttcagtgtc cccaggacag acggccaggg tcacctgtgg gggagacaac
      181 atcggaggtg aagttgtgaa ttggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atctatgctg atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gagatgaggc tgactactac
      361 tgtcaggtgt gggaccttaa tagtcatcat ctgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005149             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:13174:5680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005149
VERSION     KCWK01005149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13174:5680"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70887.1"
                     /translation="DYFCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          164 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005150             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:4530:12500
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005150
VERSION     KCWK01005150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4530:12500"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70888.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           89 a          151 c          120 g          113 t
ORIGIN      
        1 acatggggtt ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgt gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatggaggca gcaatagttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005151             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:9267:14453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005151
VERSION     KCWK01005151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9267:14453"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70889.1"
                     /translation="DYYCCSYRSGPTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           84 a          157 c          124 g          108 t
ORIGIN      
        1 acatggggtg gggtctcagg aggcagcgct ctcgggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcagtct gccctgactc
      121 agcctccctc agtgtccaag tctcttggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat tggtggttat aatggcgtct cctggtacca acaacactca gggacagccc
      241 ccaaactcct gatttatgat gtgaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggacgagg
      361 ctgattatta ctgctgctca tataggagtg gacccacttg ggttttcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005152             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:14581:15043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005152
VERSION     KCWK01005152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14581:15043"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70890.1"
                     /translation="DYYCQSADSSGNHWVF"
     J_segment       392..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           98 a          139 c          128 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctgtg agctgccaca
      121 gccaccctca gtgtcagtgt ccccaggaca gccggccagg atcacctgct ctggggaaat
      181 gctggcaaaa aaatatcctc agtggttcca gcagaagcca ggccaggccc ctgttctggt
      241 tatatataag gacactgaga ggccctcagg gatccctgag cgattctcta gctccaattc
      301 agggacagca gttatcttga ccgtcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagca gtggaaatca ttgggtcttc ggcggaggga cccggctaac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005153             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:12277:11524
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005153
VERSION     KCWK01005153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12277:11524"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70891.1"
                     /translation="DYHCSSYAGSNTLLF"
     J_segment       401..435
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          156 c          125 g          105 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcggcact ctcgggacat ctccgccatg gcctgggatc
       61 tgctcctctt caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctccctc aatgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat tggtagttat aaccgtgtct cctggtacca acaacaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtcagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggatgggg
      361 ctgattatca ctgcagctca tatgcaggta gcaacacttt gttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005154             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:26091:10246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005154
VERSION     KCWK01005154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:26091:10246"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70892.1"
                     /translation="DYYCVTWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           93 a          160 c          109 g          111 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggaacatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgtcaca tggcacagca gcgcttctta catcttcggt cctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005155             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:21106:9434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005155
VERSION     KCWK01005155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21106:9434"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70893.1"
                     /translation="DYHCLAWDTSLNWIF"
     J_segment       414..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          158 c          123 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccggaca gagggtcacc atctcctgca
      181 ttagcagcag ctccaacatc ggggcggctt attatgtatc ctggtaccaa cagttcccag
      241 gaacagcccc caaactcctc atctttgaaa ataataagcg accctctggg gtttctgacc
      301 gattctctgg ctccaagtct ggtccctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattatcac tgtttagcat gggataccag cctgaattgg atcttcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005156             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:19926:14935
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005156
VERSION     KCWK01005156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19926:14935"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..399
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70894.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       401..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          158 c          121 g          108 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgactcag ccaccctccc
      121 tgtctgcatc cccgggagca tcggccagac tcccctgcac cctgagcagt gacctcagtg
      181 ttggtagtaa aaacatgtac tggtaccagc agaagccagg gagcgctccc aggttattcc
      241 tgtactacta ctccgactca gacaagcagc tgggacctgg ggtccccaat cgagtctctg
      301 gctccaagga gacctcaagt aacacagcgt ttttgctcat ctctgggctc cagcctgagg
      361 acgaggccga ttatttctgc caggtgtttg acagtagtgt tgtgttcttc ggaggaggga
      421 cccgactgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005157             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:8516:12300
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005157
VERSION     KCWK01005157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8516:12300"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..436
                     /note="immunoglobulin light chain variable region"
     V_region        91..436
     V_segment       91..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70895.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           92 a          159 c          113 g          110 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgacccagcc aacctccctc
      121 tcagcatctc cgggagcatc agccagactc agctgcacct tgagcagtgg caatgttggt
      181 agttacagca tattctggta ccagcagaag ccagggagtc ctccccggta ccttctttac
      241 tactactcag actcaagtaa ccaccaggac tctggagtcc ccagccgctt ctctggatcg
      301 aaagatgctt cagccaatgc agggctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccac atggcacagc agcgcttctt acatcttcgg tggtgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005158             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:10114:8008
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005158
VERSION     KCWK01005158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10114:8008"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70896.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       413..449
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           92 a          158 c          127 g          110 t
ORIGIN      
        1 acatggggaa gcgcagcttc agctgtgggt acagaaggca ggactcagga caatctccag
       61 catggcctgg ttccctctcg tcctcaccct cctcactcac tgtgcagggt cctgggccca
      121 gtctgtgctg actcagcctc cctcagcgtc tgaggccgcc aggaagagtg tctccatctc
      181 ctgttctgga agcagctcca acatcggaag tcatagtgtc tcctggtacc agcaagtccc
      241 aggaacagct cccaaactcc tcatctatta tagtgatcaa cgagcctcag gtgtctctga
      301 ccgattctct ggctctcagt ctggcacgtc agcctccctg gccatcagtg ggctccagac
      361 cgaggatgag gctgattatt actgcgcagc atgggatgat agcctgaggg gttacatctt
      421 cgctgctggg acccggctcg ccgtcctagg tcagcccaag gcttccccca cggtcactct
      481 gttcccg
//
LOCUS       KCWK01005159             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:19562:20782
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005159
VERSION     KCWK01005159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:19562:20782"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..437
                     /note="immunoglobulin light chain variable region"
     V_region        106..437
     V_segment       106..397
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70897.1"
                     /translation="DYYCSSYAGSNTHWLF"
     J_segment       407..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          159 c          121 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcaggacgtc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcgggctg ccctgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccag ctacacccag gcaaagcccc
      241 caaactcatg atttatgatg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaaatct gacaacacgg cctccctgac catctctggg ctccaggctg aggatgagac
      361 tgattattac tgcagctcat atgcaggcag caacactcat tggcttttcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005160             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:19572:5184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005160
VERSION     KCWK01005160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19572:5184"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70898.1"
                     /translation="DYYCQMWGMTSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          143 c          140 g           94 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccaatga tctgactcag
      121 ccaccctcgg tgtcagagtc cccaggacag acggccagga tcacctgtgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tctgttggtc
      241 atctctggtg atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcagatgt ggggcatgac tagtgatcat ccggtattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005161             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:18825:14042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005161
VERSION     KCWK01005161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:18825:14042"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..303
                     /note="immunoglobulin light chain variable region"
     V_region        87..303
     V_segment       87..266
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70899.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       267..303
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           62 a          107 c           97 g           75 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagc agaagccagg ccagtcccct gtattggtca
      121 tctctgagga caccgaacgg ccctctggga tccctgagag attctctggc tccagctcag
      181 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      241 gttactcagc agacagtagt ggtcatggct tcttcggagg agggacccgg ctgaccgtcc
      301 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005162             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:20918:12093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005162
VERSION     KCWK01005162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20918:12093"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70900.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          162 c          109 g          111 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctctgcaac tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgttgccta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgacttacaa atcagactca gataagggcc agggctctgg agtccccagc cacttctctg
      301 gatccaaaaa tgcttcaaca aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005163             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10319:18214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005163
VERSION     KCWK01005163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10319:18214"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70901.1"
                     /translation="DYYCSSYAGSNTHWLF"
     J_segment       410..440
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           88 a          161 c          120 g          109 t
ORIGIN      
        1 acatgggggc tggggtctca gcaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac cagctacacc caggcaaagc
      241 ccccaaactc atgatttatg atgtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctgacaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 gactgattat tactgcagct catatgcagg cagcaacact cattggcttt tcggcggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005164             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:21331:10373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005164
VERSION     KCWK01005164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21331:10373"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70902.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          148 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctcctcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005165             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12859:8578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005165
VERSION     KCWK01005165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12859:8578"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70903.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          159 c          124 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagag gccagggagc gctcccaggt
      241 tattcctgta ttactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaggtaaca cagcgttttt gctcatttct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005166             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:14677:17987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005166
VERSION     KCWK01005166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:14677:17987"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70904.1"
                     /translation="DYYCQSADSSGNYPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          107 a          134 c          122 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg aactgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagcaat
      181 actggcaaaa aaatatgctc agtggttcca acagaagcca ggccaggtcc ctgtgttggt
      241 gatatataaa gacaatgaga ggccctcagg gatccctgag cgattctcta gttctagttc
      301 agggacaaca cttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagca gtggtaatta cccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005167             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:23748:4452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005167
VERSION     KCWK01005167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:23748:4452"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..391
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70905.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       395..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           93 a          152 c          120 g          105 t
ORIGIN      
        1 acatgggggg ggtacagaag gcaggactca ggacaatctc cagcatggcc tggttccctc
       61 tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg ctgactcagc
      121 ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct ggaagcagct
      181 ccaacatcgg aagtaataat gtgtcctggt accagcacct cccaggaaca gctcccaaac
      241 tcctcatcta ttataatgat caacgaggct caggtgtctc tgaccgattc tctggctcca
      301 agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat gaggctgatt
      361 attactgcgc agcgtgggat gatagcctga gtagttacat cttcgctgct gggacccggc
      421 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005168             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:18728:23515
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005168
VERSION     KCWK01005168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18728:23515"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70906.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          150 c          115 g          109 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctgtactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005169             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:22786:13403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005169
VERSION     KCWK01005169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:22786:13403"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70907.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          142 c          134 g          101 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtgaag ttgtcaactg gtaccaacag aagccaccgc aggcccctgt ggtggtcatc
      241 tatgctgatt atgaacggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacacggcca ccctgaccat cagcggagtc gcggccgggg atgaggctga ctattactgt
      361 caggtttggg acatttatac tgatcatccg gtgttgttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005170             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:3876:14391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005170
VERSION     KCWK01005170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:3876:14391"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..406
                     /note="immunoglobulin light chain variable region"
     V_region        103..406
     V_segment       103..370
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70908.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       374..406
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           89 a          134 c          129 g           92 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga attgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tctattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacagca gggtcgaggc cggggatgag gctgactatt actgtcaggt gtgggacagt
      361 agtagtaaat ggatattcgg cggggggacc cggctaaccg tcctaggtca gcccaaggct
      421 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005171             329 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:13591:5217
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005171
VERSION     KCWK01005171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 329)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13591:5217"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..291
                     /note="immunoglobulin light chain variable region"
     V_region        8..291
     V_segment       8..254
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <222..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70909.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       261..291
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>329
                     /gene="IGLC"
BASE COUNT           66 a          102 c           97 g           64 t
ORIGIN      
        1 acatgggggt caagctcacc tgcactctga gcggtgggca cagcgactac accatcgcat
       61 ggcatcagca gcagcaaggg aaggcccctc ggtatttgat gtggcttaaa agtgatggca
      121 gccacagcaa gggggacggg atccctgatc gcttctccgg ctccagctcc ggggctgagc
      181 gctacctcac catctccaac ctccagtctg aggatgaggc tgattattac tgtcagacct
      241 gggagactgg cattcaggtg ttcggcggag ggacccggct aaccgtccta ggtcagccca
      301 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005172             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:24106:10200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005172
VERSION     KCWK01005172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:24106:10200"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..388
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70910.1"
                     /translation="DYYCQSYDSSLRGVLF"
     J_segment       390..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           84 a          150 c          124 g          107 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag cagttccaac
      181 attggaggtt tttatgtgca gtggtaccag caccttccag gaacggcccc caaactcctc
      241 atctatgaaa ataatgagcg accctcaggg gtttctgatc gattctctgg ttcccagtct
      301 ggcacctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgccagtcct atgacagcag cttgcgtggt gtgttgttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005173             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:18707:18920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005173
VERSION     KCWK01005173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18707:18920"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..274
                     /note="immunoglobulin light chain variable region"
     V_region        7..274
     V_segment       7..240
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70911.1"
                     /translation="DYYCAIGLSSGYIF"
     J_segment       241..274
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        275..>315
                     /gene="IGLC"
BASE COUNT           66 a           95 c           85 g           69 t
ORIGIN      
        1 acatggggtg gcatcaatgt tgctggctac cacacacact ggtaccagca gaagccaggg
       61 aggcctcccc ggtatcttct gagatacaaa tcagactcag ataggggcca gggctctgga
      121 gtccccagcc gcttctctgg atccaaagat gtttcagcga acacagggat tttacgcatc
      181 tctgggctcc agtctgagga tgaggctgac tattactgtg ccattgggct cagcagcggt
      241 tacatcttcg gtactgggac ccggctcacc gtcccaggtc agcccaaggc ttcccccacg
      301 gtcactctgt tcccg
//
LOCUS       KCWK01005174             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:6507:14925
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005174
VERSION     KCWK01005174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6507:14925"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70912.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          155 c          124 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgataggc tgagcagtta catcttcgct
      421 gctgggaccc ggttcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005175             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:19609:18564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005175
VERSION     KCWK01005175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19609:18564"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..398
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70913.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       400..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           86 a          149 c          121 g          115 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccacttggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ttcaggttgc cccgactcag
      121 cctccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgatattg ggtattataa cgctgtgtct tggtaccaac agcatccagg caaagccccc
      241 aaactcataa tttttgacgt cattaagcgg ccctcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcgacacggc ctccctgacc atctctgggc tccgggctga ggatgaggct
      361 gattattact gcagctcata tgcaggcaga aataattttt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005176             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:9325:5110
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005176
VERSION     KCWK01005176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9325:5110"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70914.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       392..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          155 c          113 g          105 t
ORIGIN      
        1 acatggggga cagaaggcag gactcaggac aatctccagc atggcctggt tccctctcgt
       61 cctcaccctc ctcactcact gtgcagggtc ctgggcccag tctgtgctga ctcagcctcc
      121 ctcagcgtct gaggccgcca ggaagagtgt caccatctcc tgttctggaa gcacctccaa
      181 catcggaagc aataatgtat cctggtacca gcagctccca ggaacagctc ccaaactcct
      241 cttttattat aatgatcaac gagcctcagg tgtctctgac cgattctctt gctccaagtc
      301 tggcacgtca gcctccctgg ccatcagtgg gctccagacc gaggatgagg ctgattatta
      361 ctgcgcatca tgggatgata ccctgagcgg ctacatcttc ggtgctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005177             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:12143:14249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005177
VERSION     KCWK01005177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12143:14249"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70915.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       401..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          157 c          119 g          111 t
ORIGIN      
        1 acatgggggg gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccaa gcctatgctg actcagccgg cctccctctc
      121 agcatctcct ggagcatcag ccagtctcac atgcaccttc agcggtggca tcaatgttgc
      181 tgtctaccac gtacactggt accagcagaa gccagggagt cccccccggt ttcttctgag
      241 gtacaaatca gactcagata agggccaggg ctctggagtc cccagccgct tctctggatc
      301 cagtaatgtt tcagcgaaca cagggatttt acgcatttct gggctccagt ctgaggatga
      361 ggctgactat tactgtgcca ttgggcacag cagcggtcct tacatcttcg gtgctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005178             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:27720:14794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005178
VERSION     KCWK01005178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:27720:14794"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..408
                     /note="immunoglobulin light chain variable region"
     V_region        63..408
     V_segment       63..369
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70916.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       371..408
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           81 a          153 c          109 g          103 t
ORIGIN      
        1 acatgggggc cctgactcct ctcctcctcc tgctcctctc tcactgcaca ggttccctct
       61 cccagcctgt gctgactcag ccaccctccc tgtctgcatc cccgggagca tcggccagac
      121 tcccctgcac cctgagcagt gacctcagtg ttggtagtaa aaacatgtac tggtaccagc
      181 agaagccagg gagcgctccc aggttattcc tgtactacta ctccgactca gacaaccagc
      241 tgggacctgg ggtccccaat cgagtctctg gctccaagga gacctcaagt aacacagcgt
      301 ttttgctcat ctctgggctc cagcctgagg acgaggccga ttatttctgc caggtgtttg
      361 acagtagtgt tgtgttcttc ggaggaggga cccgactgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005179             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:20085:11411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005179
VERSION     KCWK01005179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20085:11411"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70917.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          147 c          130 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgggcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005180             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:20347:14909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005180
VERSION     KCWK01005180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20347:14909"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..446
                     /note="immunoglobulin light chain variable region"
     V_region        98..446
     V_segment       98..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70918.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       412..446
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           90 a          162 c          122 g          110 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt agtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtatgacagt agtgctaatg tcttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01005181             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:14986:19888
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005181
VERSION     KCWK01005181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:14986:19888"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70919.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          156 c          126 g          108 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa cagtgtcgcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtatcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatgatg atcaacgagc ctcgggtgtc tctgaccgat
      301 tctctggctc caggtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagaggttac atcttcggtg
      421 atgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01005182             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:13362:10762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005182
VERSION     KCWK01005182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13362:10762"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70920.1"
                     /translation="DYYCQSSHSRVNHPFF"
     J_segment       398..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          103 a          138 c          124 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagac ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaac
      181 actggcaaaa aaatatgctc agtggttcca gcagaagcca ggccaggccc ctgtgttggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca tcgcacagca gggttaatca tccgtttttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005183             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:8500:6390
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005183
VERSION     KCWK01005183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8500:6390"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70921.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          142 c          132 g          102 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctttgat ctgactcagc
      121 caccctcgct gtcagtgtcc ccaggacaga cggccaggat cacctgtgga ggagacaaca
      181 ttggaaatga agttgtcaac tggtaccagc agaggccacc gcaggcccct gtactggtca
      241 tctatgctga ttatgaaagg ccctcaggga tccctgcacg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcggag tcgaggccgg ggatgaggct gactattatt
      361 gtcaggtgtg ggacatttat attgaccatc cggtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005184             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:20260:16579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005184
VERSION     KCWK01005184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:20260:16579"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..444
                     /note="immunoglobulin light chain variable region"
     V_region        120..444
     V_segment       120..406
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70922.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       412..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           94 a          148 c          145 g           95 t
ORIGIN      
        1 acatgggtca acgcagagta catggggggg cctcaggagg cagcattgac ggtgcctcag
       61 ccatggcctg gacttttctc ctcctcggcc tccttgctta ctgcacaggc tctgcggcct
      121 cctatgatct gactcagcca ccctcggtgt cagtgtcccc aggacagacg gccaggatca
      181 cctgcggggg agacaagatt ggaagtgaag ttgtgaactg gtaccagcag aagccagcgc
      241 acgcccctgt gctggtcatc tatgctaata gcgaacggcc ctcagggatc cctgagcgat
      301 tctctggctc caaatcaggg aacacggcca ccctgaccat cagcggggtc gaggccgggg
      361 gtgaggctga ctattactgt caggtgtggg acatgcgtag tgatcaaccg ctattcggcg
      421 gagggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005185             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:23489:9669
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005185
VERSION     KCWK01005185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23489:9669"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..447
                     /note="immunoglobulin light chain variable region"
     V_region        111..447
     V_segment       111..404
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70923.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       410..447
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           95 a          157 c          122 g          111 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctct ccttctcact ctgctggttc actgcacagg gtcctgggcc cagtctgtgc
      121 tgacgcagcc gccctcagca tctggggccc ccgggcagag ggtcaccatc tcctgcactg
      181 ggagcagctc caacatcggg gcgggttatt atgtatcctg gtaccagcag ttcccaggaa
      241 cagcccccaa actcctcatc tatgaaaata ataaacgacc ctcaggggtt tctgaccgat
      301 tctctggctc caagtctggt acctcagcct ccctgaccat cactggactc caatctgagg
      361 atgaggctga ttattactgc tcagcatggg atagcagcct gagtatcaat tacatcttcg
      421 gttctgggac ccgtctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt
      481 tcccg
//
LOCUS       KCWK01005186             394 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:4294:9361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005186
VERSION     KCWK01005186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 394)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4294:9361"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..356
                     /note="immunoglobulin light chain variable region"
     V_region        8..356
     V_segment       8..317
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <284..>328
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70924.1"
                     /translation="DYYCAMWHSSVYGLF"
     J_segment       319..356
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        357..>394
                     /gene="IGLC"
BASE COUNT           83 a          121 c           96 g           94 t
ORIGIN      
        1 acatgggcag cctgtgctga cccagccaac ctccctctca gcatctccgg gagcatcagc
       61 cagactcagc tgcaccttga gcagtggcat caatgttggt agttacagca tattctggta
      121 ccagcagaag ccagggagtc ctccccgatt ccttctgtac tactactcag actcaaataa
      181 tcaccagggc tctggagtcc ccagccgctt ctctggatcc aaagatactt cagccaatgc
      241 agggctttta ctgatctctg ggctccagtc tgaagatgag gctgactatt actgtgccat
      301 gtggcacagt agtgtttatg gcttattcgg aggagggacc cggctgaccg tcctaggtca
      361 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005187             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:19153:13833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005187
VERSION     KCWK01005187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19153:13833"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..343
                     /note="immunoglobulin light chain variable region"
     V_region        13..343
     V_segment       13..304
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70925.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       313..343
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>381
                     /gene="IGLC"
BASE COUNT           77 a          122 c           95 g           87 t
ORIGIN      
        1 acatgggggg cccagtctgt gctgacgcag ccgccctcag catctggggc ccccggacag
       61 agggtcacca tttcctgcat tagcagtagc tccaacatcg gggcggctta ttatgtatcc
      121 tggtaccaac agttcccagg aacagccccc aaactcctca tctttgaaaa taataagcga
      181 ccctcagggg tttctgaccg attctctggc tccaagtctg gtccctcagc ctccctgacc
      241 atcactggac tccaatctga ggatgaggct gattattact gtttagcatg ggataccagc
      301 ctgaattgga tcttcggcgg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      361 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005188             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:26358:11064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005188
VERSION     KCWK01005188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:26358:11064"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..393
                     /note="immunoglobulin light chain variable region"
     V_region        63..393
     V_segment       63..358
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <321..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70926.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       363..393
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>431
                     /gene="IGLC"
BASE COUNT           82 a          141 c          107 g          101 t
ORIGIN      
        1 acatgggggt ctgggctctg ctcctcctca ccctcctcac tcagggcaca ggatcctggg
       61 ctcaggctgc cccgactcag actccctctg tgtccgggtc tcctggacag tcggtcacca
      121 tctcctgcac tggaaccagc agtgatattg ggtattatca tgctgtgtct tggtaccaac
      181 atcatccagg caaagccccc aaactcatga tttatgaggt caataaacgg cccgcagggg
      241 tctctgatcg cttctctggc tccaagtctg gcaacacggc ctccctgacc atctctgggc
      301 tccagactga ggatgaggct gattattact gcagctcata tgcaggcagc aacactttat
      361 tcttcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      421 ctctcttccc g
//
LOCUS       KCWK01005189             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:4174:14284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005189
VERSION     KCWK01005189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:4174:14284"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..453
                     /note="immunoglobulin light chain variable region"
     V_region        123..453
     V_segment       123..416
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70927.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       417..453
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           94 a          157 c          124 g          116 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactt cacagttcca gggtcctggg
      121 cccagtctgt gctgacgcag ccgccctcag tgtctggggc gcccggacag agggtcacca
      181 tctcctgcac tgggagcagc tccaacattg gagattattt tgtgcagtgg taccagcacc
      241 ttccaggaac ggcccccaaa ctcatcatct atgaaaataa taagcgaccc tcagggattt
      301 ctgatcgatt ctctggctcc cagtctggaa cctcagcctc cctgaccatc actggactcc
      361 agtctgagga tgaggctgat tattactgcc agtcctatga cagcagtttg attgctgtgt
      421 tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      481 ctctcttccc g
//
LOCUS       KCWK01005190             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18963:16244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005190
VERSION     KCWK01005190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18963:16244"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70928.1"
                     /translation="DYYCQSADSSGNHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          134 c          125 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc agtggttcca gcagaagcca ggccaggccc ctgtgttggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgaa cgattctcta gttccagttc
      301 agggacaaca gttaccttga ccatcagcgg ggcccaggta gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagca gtggtaatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005191             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:14479:12193
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005191
VERSION     KCWK01005191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14479:12193"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70929.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          160 c          112 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctggactc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005192             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:9125:19132
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005192
VERSION     KCWK01005192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9125:19132"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70930.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       408..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          152 c          129 g          113 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg gttcactgca cagggtcctg ggcccagtct
      121 gtgttgacgc agccgccctc agcatctggg gcccccgggc agagggtcac catctcctgc
      181 actgggagca gctccaacat cggggcgggt ttttatgttt cctggtacca gcagttccca
      241 ggaacagccc ccaaactcct catctttgaa aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggttcctca gcctccctga ccatcactgg actccaatct
      361 gaggatgagg ctgattatta ttgttcatca tgggaaagca gcctgaattg ggtattcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01005193             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:6964:9890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005193
VERSION     KCWK01005193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6964:9890"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70931.1"
                     /translation="DYYCQVWDMNSHHLLI"
     J_segment       391..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          138 c          138 g           98 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagg
      121 caccctcgat ttcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtgaac tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tgtatgctga tagcgagcgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacatgaat agtcatcatc tgttaatcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005194             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:26681:12122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005194
VERSION     KCWK01005194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:26681:12122"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70932.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          164 c          122 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggcttacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005195             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:12384:15847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005195
VERSION     KCWK01005195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12384:15847"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70933.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          153 c          120 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tccagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaacagtgtc gccatctcct gttctggagg cagctccaac
      181 atcggaagtc atagtgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattatg atgatcaacg agcctcaggt gtctctggcc gattctctgg ctccaggtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagaggt tacatcttcg gtgatgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005196             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:12929:13253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005196
VERSION     KCWK01005196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12929:13253"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70934.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       400..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          156 c          126 g          102 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcgtctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttctgt tcacgcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgtaccc gcagcagagg
      181 caacattgac aatagttatg tgcagtggta ccagcagcgc ccgggcattg ccccgaccac
      241 agtgatttac agagataacc aaagagcctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctggg ctgaagtctg aggacgaggc
      361 tgactactac tgtcagtcta ctgatggcaa ctacaatcgg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005197             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:24105:9800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005197
VERSION     KCWK01005197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24105:9800"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..237
                     /note="immunoglobulin light chain variable region"
     V_region        8..237
     V_segment       8..199
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <162..>209
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70935.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       201..237
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>275
                     /gene="IGLC"
BASE COUNT           57 a           88 c           75 g           55 t
ORIGIN      
        1 acatggggca ctggtaccag cacaagccac cgcaggcccc tgtactggtc atcttttatt
       61 ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca gggaacaccg
      121 ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac tgtcaggtgt
      181 gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc gtcctaggtc
      241 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005198             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:12391:13092
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005198
VERSION     KCWK01005198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12391:13092"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70936.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       414..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          157 c          123 g          109 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccggaca gagggtcacc atctcctgca
      181 ttagcagcag ctccaacatc ggggcggctt attatgtatc ctggtaccaa cagttcccag
      241 gaacagcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtccctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattac tgtttagcat gggataccag cctgaattgg atcttcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005199             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:13301:21553
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005199
VERSION     KCWK01005199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13301:21553"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..389
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70937.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       393..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          152 c          118 g          105 t
ORIGIN      
        1 acatgggggg tacagaaggc aggactcagg acaatctcca gcatggcctg gttccctctc
       61 gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc agtctgtgct gactcagcct
      121 ccctcagcgt ctgaggccgc caggaagagt gtcaccatct cctgttctgg aagcagctcc
      181 aacatcggaa gtaataatgt gtcctggtac cagcacctcc caggaacagc tcccaaactc
      241 ctcatctatt ataatgatca acgaggctca ggtgtctctg accgattctc tggctccaag
      301 tctggcacgt cagcctccct ggccatcagt gggctccaga ccgaggatga ggctgattat
      361 tactgcgcag cgtgggatga tagcctgagt agttacatct tcgctgctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01005200             490 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:23059:20164
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005200
VERSION     KCWK01005200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 490)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:23059:20164"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..452
                     /note="immunoglobulin light chain variable region"
     V_region        122..452
     V_segment       122..415
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>424
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70938.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       416..452
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>490
                     /gene="IGLC"
BASE COUNT           90 a          158 c          127 g          115 t
ORIGIN      
        1 acatgggggt ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcacttc acagttccag ggtcctgggc
      121 ccagtctgtg ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat
      181 ctcctgcact gggagcagct ccaacattgg agattatttt gtgcagtggt accagcacct
      241 tccaggaacg gcccccaaac tcctcatcta tgaaaataat aagcggccct cagggatttc
      301 tgatcgattc tctggctccc agtctggaac ctcagcctcc ctgaccatca ctggactcca
      361 gtctgaggat gaggctgatt attactgcca gtcctatgac agcagtttga tcgctgtgtt
      421 attcggggga gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac
      481 tctcttcccg
//
LOCUS       KCWK01005201             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:16432:6860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005201
VERSION     KCWK01005201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16432:6860"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70939.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          161 c          119 g          108 t
ORIGIN      
        1 acatggggac tgcagggaaa gagactgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcgtcaatg
      181 tgggtagtta cagcgtattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacca gtcagactca aggaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc tgttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccctatggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005202             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:25655:3400
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005202
VERSION     KCWK01005202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:25655:3400"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..389
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70940.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          143 c          133 g           94 t
ORIGIN      
        1 acatgggggc tgggtctcag gaggcagcat tgacggtgcc tcagccatgg cctggaccct
       61 tctcctcctc ggcctcctcg cttactgcac aggctctgcg acctcctatg aattgactca
      121 gtcaccctca gtgtcagcgg cctcaggaca gccggccagg atcacctgtg ggggagacaa
      181 cattggaact aaaactgtgc actggtacca acagaagcca ccgcagggcc ctgtattggt
      241 catctttgct gatagtagac ggccctcagg gatccctgag cgattctctg gctccaactc
      301 agggaacacc gccaccctga ccatcagcag ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta gtagtaaatg gatattcggc ggggggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005203             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:13516:17233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005203
VERSION     KCWK01005203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13516:17233"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70941.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          153 c          119 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc attctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005204             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12407:6914
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005204
VERSION     KCWK01005204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12407:6914"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70942.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           88 a          143 c          127 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacggcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005205             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:25938:3949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005205
VERSION     KCWK01005205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:25938:3949"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70943.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          158 c          116 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca aatgcacctt cagcggtgtc atcaatgttg
      181 ctgactacca catacactgg taccagcaga agccagggag tcccccccga tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc tgcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacaca gcagcggtcc ttacttcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005206             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:4689:9915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005206
VERSION     KCWK01005206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:4689:9915"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70944.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          160 c          123 g          108 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtact gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccaggctcc cctgcaccct gagcagtgac
      181 ctcagtgttg gaagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcaactgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag atgtatgaca gtagtgatgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01005207             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:11532:15089
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005207
VERSION     KCWK01005207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11532:15089"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70945.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          156 c          125 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctagaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaagtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005208             382 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:17861:2235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005208
VERSION     KCWK01005208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 382)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17861:2235"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..344
                     /note="immunoglobulin light chain variable region"
     V_region        20..344
     V_segment       20..306
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <269..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70946.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       308..344
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>382
                     /gene="IGLC"
BASE COUNT           79 a          120 c          106 g           77 t
ORIGIN      
        1 acatgggggc tctgcggcct cctatgatct gactcagcca ccctcggtgt cagtgtcccc
       61 aggacagacg gccaggatca cctgtggggg agacaacatt ggaagtcaaa gtgtacactg
      121 gtaccagcac aagccaccgc aggcccctgt tctgctcatc ttttattata ccgaacggcc
      181 ctcaggaatc cctgagcgat tctctggctc caaatcaggg aacaccgcca ccctgaccat
      241 cagcggggtc gaggccgggg atgaggctga ctattactgt caggtgtggg acacaactat
      301 tgatcacggc ttgttcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc
      361 cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005209             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:25156:12772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005209
VERSION     KCWK01005209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:25156:12772"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..405
                     /note="immunoglobulin light chain variable region"
     V_region        84..405
     V_segment       84..368
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <333..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70947.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       369..405
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>443
                     /gene="IGLC"
BASE COUNT           86 a          140 c          117 g          100 t
ORIGIN      
        1 acatggggag ctctgggtgt ctcaccatgg cctggattcc tctcctactc cccatcctca
       61 ctttctgcac aggctctgca gcctcctatg agctgacaca gccaccctcg gtgtcagtgt
      121 ccccaggaca gccggccagg atcacctgct ctggagatgt attgccaaaa aaatatgctt
      181 attggttcca gcagaagcca ggccagtccc ctgtattggt catctctgag gacaccgaac
      241 ggccctctgg gatccctgag agattctctg gctccagctc agggacagtg gccaccttga
      301 ctatcagtgg ggcccaggtg gaggatgaag ctgactacta ctgttactca gcagacagta
      361 gtggtcatgg cttcttcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg
      421 ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005210             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:16611:20681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005210
VERSION     KCWK01005210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16611:20681"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70948.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          144 c          140 g           92 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacggg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccagcg cacgcccctg tgctggtcat
      241 ctatgctaat agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg ggtgaggctg actattactg
      361 tcaggtgtgg gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005211             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:21137:20206
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005211
VERSION     KCWK01005211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21137:20206"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..409
                     /note="immunoglobulin light chain variable region"
     V_region        79..409
     V_segment       79..372
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70949.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       373..409
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           81 a          148 c          114 g          104 t
ORIGIN      
        1 acatggggga caatctccag catggcctgg ttccctctcg tcctcaccct cctcactcac
       61 tgtgcagggt cctgggccca gtctgtgctg actcagcctc cctcagcgtc tgaggccgcc
      121 aggaagagtg tctccatctc ctgttctgga agcagctcca acatcggaag tcatagtgtc
      181 tcctggtacc agcaagtccc aggaacagct cccaaactcc tcatctatta tagtgatcaa
      241 cgagcctcag gtgtctctga ccgattctct ggctctcagt ctggcacgtc agcctccctg
      301 gccatcagtg ggctccagac cgaggatgag gctgattatt actgcgcagc atgggatgat
      361 agcctgaggg gttacatctt cggtgctggg acccggctcg ccgtcctagg tcagcccaag
      421 gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01005212             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:9420:9630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005212
VERSION     KCWK01005212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9420:9630"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70950.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          142 c          132 g           94 t
ORIGIN      
        1 acatggggtg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgaa ttgactcagt
      121 caccctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa aactgtgcac tggtaccaac agaagccacc gcagggccct gtattggtca
      241 tctttgctga tagtagacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005213             246 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:11114:6303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005213
VERSION     KCWK01005213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 246)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 246)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..246
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11114:6303"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..208
                     /note="immunoglobulin light chain variable region"
     V_region        6..208
     V_segment       6..169
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <139..>180
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70951.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       171..208
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        209..>246
                     /gene="IGLC"
BASE COUNT           46 a           73 c           66 g           61 t
ORIGIN      
        1 atgggattcc tgtactacta ctccgactca gacaagcagc tgggacctgg ggtccccaat
       61 cgagtctctg gttccaagga gacctcaagt aacacagcgt ttttgctcat ctctgggctc
      121 cagcctgagg acgaggccga ttatttctgc caggtgtttg acagtagtgt tgtgttcttc
      181 ggaggaggga cccgactgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      241 ttcccg
//
LOCUS       KCWK01005214             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:5864:14128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005214
VERSION     KCWK01005214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:5864:14128"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..388
                     /note="immunoglobulin light chain variable region"
     V_region        58..388
     V_segment       58..351
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <313..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70952.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       352..388
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           85 a          131 c          110 g          100 t
ORIGIN      
        1 acatggggaa gcagaatcat gatgcctgtg tctctcccag ttccagggtc ctgggcccag
       61 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      121 tgcactggga gcagctccaa cattggagat tattttgtgc agtggtacca gcaccttcca
      181 ggaacggccc ccaaactcct catctatgaa aataataagc gaccctcagg aatttctgat
      241 cgattctctg gctcccagtc tggaacctca gcctccctga ccatcactgg actccagtct
      301 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtttgattgc tgtgttattc
      361 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      421 ttcccg
//
LOCUS       KCWK01005215             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:18547:15517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005215
VERSION     KCWK01005215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18547:15517"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70953.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           90 a          157 c          117 g          110 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcatctcctg gaacatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 gtctaccacg tacactggta ccaacagaag ccagggagtc ccccccggta tcttctgagg
      241 tacaaatcag actcagataa gggccagggc tctggggtcc ccagccgctt ctctggatcc
      301 agtaatgctt cagcgaacac agggatttta cgcatttctg ggctccagtc tgaggatgag
      361 gctgactatt actgtgccat tgggcacagc agcggtcttt acatcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005216             380 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:9464:2469
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005216
VERSION     KCWK01005216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 380)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9464:2469"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..342
                     /note="immunoglobulin light chain variable region"
     V_region        12..342
     V_segment       12..303
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <267..>314
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70954.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       305..342
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        343..>380
                     /gene="IGLC"
BASE COUNT           75 a          117 c          101 g           87 t
ORIGIN      
        1 acatgggggc ccagtctgtg ctgacgcagc cgccctcagt gtctggggcg cccgggcaga
       61 gggtcaccat ctcctgcact gggagcagct ccaacattgg aggttattat gtgcagtggt
      121 accagcagct tccaggaacg gcccccaaac tcctcatcta tgaaaatgat aaacgaccct
      181 caggggtttc tgatcgattc tctggctccc agtctgatac ctcagcctcc ctgaccatca
      241 ctggactcca gtctgaggat gaggctgatt attactgcca gtcctatgac agcagcttaa
      301 gtgttgtgtt attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      361 cctcggtcac tctcttcccg
//
LOCUS       KCWK01005217             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:24596:5116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005217
VERSION     KCWK01005217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24596:5116"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70955.1"
                     /translation="DYYCASYEGGNTFFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          157 c          121 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtaaaatt gggtatcgtg atgctgtgtc ctggtaccaa gagcatccag gcaaagcccc
      241 caaactcttg atttttgacg tcaataagcg gccctcaggg atctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aagatgaggc
      361 tgattattac tgcgcctcat atgaaggcgg caacactttc ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005218             337 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:25352:15794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005218
VERSION     KCWK01005218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 337)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 337)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..337
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:25352:15794"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..299
                     /note="immunoglobulin light chain variable region"
     V_region        7..299
     V_segment       7..263
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <227..>271
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70956.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       267..299
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        300..>337
                     /gene="IGLC"
BASE COUNT           74 a           98 c          101 g           64 t
ORIGIN      
        1 acatgggtca gcggcctcag gacagccggc caggatcacc tgtgggggag acaacattgg
       61 aactaaaact gtgcactggt accaacagaa gccaccgcag ggccctgtat tggtcatctt
      121 tgctgatagt agacggccct cagggatccc tgagcgattc tctggctcca actcagggaa
      181 caccgccacc ctgaccatca gcagggtcga ggccggggat gaggctgact attactgtca
      241 ggtgtgggac agtagtagta aatggatatt cggcgggggg acccggctaa ccgtcctagg
      301 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005219             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:20742:10191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005219
VERSION     KCWK01005219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20742:10191"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70957.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       391..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           90 a          144 c          133 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgttaact ggtaccagca gaagccaccg caggcccctg tcctggtcat
      241 ctatgctaat aacgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg ggcgttacta gtgatcatcc cttattcgga ggagggaccc ggctgaccgt
      421 ccaaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005220             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12353:3652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005220
VERSION     KCWK01005220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12353:3652"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70958.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          156 c          121 g          109 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatgt tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacgcttt attcttcgga cgagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005221             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:20920:20048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005221
VERSION     KCWK01005221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20920:20048"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70959.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       409..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          156 c          126 g          113 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca ccctctcctg
      181 cactgggagc agctccaaca ttggagatta ttatgtgcag tggtaccagc agcttccagg
      241 aacggccccc aaactcctca tctatgaaaa taataagcga ccctcagggg tttctgatcg
      301 attctctggc tcccagtctg gtacctcagc ctccctgacc atcactggac tccagtctga
      361 cgatgaggct gattattact gtcagtccta tgatagcagc ctgagtgttg tgttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01005222             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:22452:10560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005222
VERSION     KCWK01005222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22452:10560"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..425
                     /note="immunoglobulin light chain variable region"
     V_region        105..425
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70960.1"
                     /translation="DYFCQVWDSGSDHYIF"
     J_segment       392..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>467
                     /gene="IGLC"
BASE COUNT           86 a          148 c          133 g          100 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagttgactc
      121 agctaccctc ggtgtcagcg gcctctggac agacggccag gatcacctgt gggggagaca
      181 acattggaac tacatatgtg cactggtacc agcagaagcc accacaggcc cctgtgcagg
      241 tcatctttgc tgatagcaaa cggccctcag gggtccctga ccgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 tctgtcaggt gtgggacagt ggtagtgatc attacatctt cggtgttggg acccggctca
      421 ccgtcttagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01005223             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:2864:10696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005223
VERSION     KCWK01005223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:2864:10696"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70961.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          147 c          131 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggatctgcgg cctccgatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta agagtgtgca ctggtaccag cacaagccac cgcaggcccc tatcctggtc
      241 atctattatt ataccgaacg gccctcggcg atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacactac tattgatcat ggctttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005224             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:23470:3656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005224
VERSION     KCWK01005224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:23470:3656"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..439
                     /note="immunoglobulin light chain variable region"
     V_region        93..439
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70962.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>479
                     /gene="IGLC"
BASE COUNT           93 a          162 c          110 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca aataaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtagtg
      421 ggacccggct caccgtcctg ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005225             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:20563:6278
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005225
VERSION     KCWK01005225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20563:6278"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70963.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          165 c          122 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcaaaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005226             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:22970:7379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005226
VERSION     KCWK01005226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22970:7379"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70964.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          142 c          133 g          101 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtgaagt tgtcaactgg taccaacaga agccaccgca ggcccctgtg gtggtcatct
      241 atgctgatta tgaacggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acacggccac cctgaccatc agcggagtcg cggccgggga tgaggctgac tattactgtc
      361 aggtttggga catttatact gatcatccgg tgttgttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005227             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11343:23731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005227
VERSION     KCWK01005227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11343:23731"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70965.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          163 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg ccctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005228             331 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:19360:17327
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005228
VERSION     KCWK01005228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 331)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19360:17327"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..293
                     /note="immunoglobulin light chain variable region"
     V_region        110..293
     V_segment       110..254
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>265
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70966.1"
                     /translation="DYHCQVFDSRDVLF"
     J_segment       256..293
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        294..>331
                     /gene="IGLC"
BASE COUNT           54 a          109 c           89 g           79 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagacaa
      121 ggaggtggga cctggggtcc ccaatcgagt ctctggctcc aaggaaacct catctaacac
      181 agcgtttttg ctcatctctg gactccagcc tgaggacgag gccgattatc actgtcaggt
      241 gtttgacagt cgtgatgtgt tgttcggagg agggacccgg ctgaccgtcc taggtcagcc
      301 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005229             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:18112:11577
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005229
VERSION     KCWK01005229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18112:11577"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70967.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          152 c          121 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005230             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:11530:11354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005230
VERSION     KCWK01005230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11530:11354"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70968.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          157 c          127 g          110 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccgggaa gagtgtctcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc tcagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagcggttac atcttcggtg
      421 ctgggacccg gctcgccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01005231             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:22861:3949
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005231
VERSION     KCWK01005231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22861:3949"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70969.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       373..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           96 a          141 c          113 g           96 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga agaattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtcca gatcatctat gaggacagta
      241 aacggccctc tgggatccct gagagaatct ctggctccag ctcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aagctgacta ctactgtttc tcaacagaca
      361 ccagtggtaa tcgggtattc ggcggaggga cccgtctaac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005232             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15008:7873
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005232
VERSION     KCWK01005232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15008:7873"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..431
                     /note="immunoglobulin light chain variable region"
     V_region        98..431
     V_segment       98..394
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70970.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       395..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           89 a          158 c          121 g          101 t
ORIGIN      
        1 acatggggga gagccctgag gagtctgcac catggcctgg accccaatcc tcctcctcct
       61 cctcactctc ctccttcact gcacagggtc tctctcccag cctgtgctga ctcagtcgcc
      121 ctctgtctct gcctccctgg gagcctcggt caaactcacc tgtactttga acagtgggca
      181 cagcagctac accatcgcat ggcatcagca gcagcaaggg aaggcccccc ggtacttgat
      241 gtggcttaaa agtgaaggca gccatagcaa gggggacggg atccctgatc gcttctcagg
      301 ctccagctcc ggggctgagc gctacctcac catctccaac ctccagtctg aggatgaggc
      361 tgattattac tgtcagacct gggatactga cattgtgtta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005233             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:6473:3158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005233
VERSION     KCWK01005233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6473:3158"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..295
                     /note="immunoglobulin light chain variable region"
     V_region        8..295
     V_segment       8..258
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <220..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70971.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       259..295
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        296..>333
                     /gene="IGLC"
BASE COUNT           71 a          102 c           84 g           76 t
ORIGIN      
        1 acatggggga agagtgtcac catctcctgt tctggaagca gctccaacat cggaagtaat
       61 aatgtgtcct ggtaccagca cctcccagga acagctccca aactcctcat ctattataat
      121 gatcaacgag gctcaggtgt ctctgaccga ttctctggct ccaagtctgg cacgtcagcc
      181 tccctggcca tcagtgggct ccagaccgag gatgaggctg attattactg cgcagcgtgg
      241 gatgataggc tgagcagtta catcttcgct gctgggaccc ggctcaccgt cctaggtcag
      301 cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005234             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:8081:14036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005234
VERSION     KCWK01005234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8081:14036"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70972.1"
                     /translation="LYYCCSYTTSSTYIF"
     J_segment       399..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          160 c          113 g          112 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cactgacgtt ggtggttata actctgtctc ctggtaccaa caggacccag gcaaagcccc
      241 caaactcatc atttatggtg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tctttattac tgttgttcat atacaaccag tagcacttac atcttcggta ctgggacccg
      421 gctaaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01005235             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:10499:5106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005235
VERSION     KCWK01005235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10499:5106"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70973.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          156 c          118 g          111 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgtctacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccagtaatgc ttcagcgaac acagggattt tacgcatttc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacaca gcagcggtct ttacatcttc ggtgctggga
      421 cccggctcag cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005236             283 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:16703:11237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005236
VERSION     KCWK01005236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 283)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16703:11237"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..245
                     /note="immunoglobulin light chain variable region"
     V_region        7..245
     V_segment       7..206
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <173..>217
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70974.1"
                     /translation="DYYCSSWESSLNWIF"
     J_segment       208..245
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        246..>283
                     /gene="IGLC"
BASE COUNT           59 a           86 c           68 g           70 t
ORIGIN      
        1 acatgggggt ttttatgtgt cctggtacca acagttccct ggaacagccc ccaaactcct
       61 catctatgaa aataataagc gaccctcagg ggtttctgac cgattctctg gctccaagtc
      121 tggttcctca gcctccctga ccatcactgg actccagtct gaggatgagg ctgattatta
      181 ctgctcatca tgggaaagca gcctgaattg gatattcggc ggagggaccc ggctgaccgt
      241 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005237             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:4759:19275
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005237
VERSION     KCWK01005237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:4759:19275"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70975.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           96 a          146 c          128 g           90 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgaac tcctatgagc tgactcagcc
      121 accctcagtg tcagcggcct caggacagac ggccaggatc acctgtggcg gagacaacat
      181 tggaattaaa aatgtacact ggtaccacca gaagccaccg caggcccctg tgctggtcat
      241 ctttgctgat aacaaacggc cctcagggat ccctgagcga ttctctgcct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatgggt attcggcgga gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005238             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:11304:17756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005238
VERSION     KCWK01005238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11304:17756"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..254
                     /note="immunoglobulin light chain variable region"
     V_region        8..254
     V_segment       8..217
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70976.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       218..254
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           60 a           91 c           73 g           68 t
ORIGIN      
        1 acatgggatc ggaagttata atgtgtcctg gtaccagcag ctcccaggaa cagctcccaa
       61 actcctcatc tattataatg atcaacgagc ctcaggtgtc tctgaccgat tctctggctc
      121 caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg atgaggctga
      181 ttattactgc gcagcatggg atgatagcct gagcggttac atcttcgctg ctgggacccg
      241 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01005239             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:17093:3969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005239
VERSION     KCWK01005239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17093:3969"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70977.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          143 c          135 g          101 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga agttgtcaac tggtaccaac agaagccacc gcaggcccct gtggtggtca
      241 tctatgctga ttatgaacgg ccctcaggga tccctgaccg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcggag tcgcggccgg ggatgaggct gactattact
      361 gtcaggtttg ggacatttat actgatcatc cggtgttgtt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005240             415 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:21992:19537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005240
VERSION     KCWK01005240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 415)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21992:19537"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..376
                     /note="immunoglobulin light chain variable region"
     V_region        87..376
     V_segment       87..340
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>349
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70978.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       341..376
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        377..>415
                     /gene="IGLC"
BASE COUNT           84 a          125 c          115 g           91 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagt gtccccagga cagacggcca agatcacctg
      121 ctctggagat gcactgccaa aaaaatatgc ttattggttc cagcagaagc caggccagtc
      181 ccctgtgttg atcgtcgatg aggacagcaa acggccctct gggatccctg agagattctc
      241 tggctccagc tcagggacag tggccacctt gactatcagt ggggcccagg tggaggatga
      301 tgctgactac tactgttact cagcagacag cagtggttat ggcttattcg gaggagggac
      361 ccggctgacc gtcctacgtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005241             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:6707:12749
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005241
VERSION     KCWK01005241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6707:12749"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70979.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       393..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT          106 a          135 c          122 g          102 t
ORIGIN      
        1 acatgggggt gtggttctag gaggaagagc tctgggtgtc tcaccatgac ctggaccact
       61 gttctgctcc cctttctcac tctctgcaca ggctctgagg cctcctatga gctgacacag
      121 ccaccctcag tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagaaata
      181 ctggcaaaaa aatatactca gtggttccag cagcagccag gccaggcccc tttcctggtg
      241 atatataaag acagtgagag gccctcaggg atccctgagc gattctctag ttccagttca
      301 gggacaacaa ttaccttgac catcagtggg gcccaggcag aagatgaggc tgactattac
      361 tgtcaatcag tagacagcag tggaaatctt ccgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005242             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:21872:11792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005242
VERSION     KCWK01005242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21872:11792"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..271
                     /note="immunoglobulin light chain variable region"
     V_region        74..271
     V_segment       74..235
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <199..>243
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70980.1"
                     /translation="DYYCCSYTTDSTYIF"
     J_segment       236..271
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        272..>309
                     /gene="IGLC"
BASE COUNT           55 a          103 c           79 g           72 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc acccccccaa agtcctgact tatggtgtca gtaatcgggc ctcaggggtc
      121 tctgaccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc
      181 caggctgagg acgaggctga ttattactgt tgttcatata caaccgatag cacttacatc
      241 ttcggtagtg ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact
      301 ctgttcccg
//
LOCUS       KCWK01005243             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:24541:18128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005243
VERSION     KCWK01005243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24541:18128"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..435
                     /note="immunoglobulin light chain variable region"
     V_region        87..435
     V_segment       87..395
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70981.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       398..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           92 a          156 c          117 g          108 t
ORIGIN      
        1 acatgggggg gaaagaggct gtgtccacca tggcctggac tcctctcctc ctcctgctcc
       61 tctctcactg cacaggttcc ctctccaagc ctatgctgac tcagccggcc tccctctcag
      121 catctcctgg ggcatcagcc agtctcacat gcaccttcag cggtggcatc aatgttgctg
      181 gctaccacat acactggtat cagcagaagc cagggagtcc tccccggcat cttctgagat
      241 acacatcaga ctcagataag ggccagggct ctggagtccc cagccgcttc tctggatcca
      301 aagatacttc agcgaacaca gggattttac gcatctctgg gctccagtct gaggatgagg
      361 ctgactatta ctgtgccatt gggcacagta gcggtgatta catcttcggt gctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005244             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:24439:10528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005244
VERSION     KCWK01005244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24439:10528"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70982.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       413..446
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           87 a          161 c          127 g          109 t
ORIGIN      
        1 acatgggggg ctcattcctg gctgtggctc aggaagcaga gcctggagca tctccaccat
       61 ggcctgggct ccactcctcc tcaccctcct cgctcactgc acagggtctt gggctgaggt
      121 tgtgttcact cagccccatt ctgtgtcggg gtctccgggg cagacggtca ccatctcctg
      181 cacccgcagc agtggcagca ttgacaacgg ctttgtgtac tggtaccagc agcggccggg
      241 cagcgctccc accactgtga tttacaaaga taaccaaaga ccctctgggg tccctgatcg
      301 gttctctggc tccatcgaca gctcctccaa ctctgcctcc ctcaccatct ctggactgaa
      361 atctgaggac gaggctgact attactgtca gtcttatgac agcagcagtg tattattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01005245             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:11980:15806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005245
VERSION     KCWK01005245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11980:15806"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..443
                     /note="immunoglobulin light chain variable region"
     V_region        119..443
     V_segment       119..406
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70983.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       410..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           93 a          146 c          142 g          100 t
ORIGIN      
        1 acatggggga ggaacctgcc cagcctgggc ctcaggaggc agcattgacg gtgcctcagc
       61 catggcctgg acttttctcc tcctcggcct ccttgcttac tgcacaggct ctgcggcctc
      121 ctatgatctg actcaggcac cctcgatttc agtgtccccc ggacagacgg ccaggatcac
      181 ctgtggggga gacaacattg gaagtgaagt tgtgaactgg taccagcaga agccaccgca
      241 ggcccctgtg ttggtcatgt atgctgatag cgagcggccc tcagggatcc ctgagcgatt
      301 ctctggctcc aaatcaggga acacggccac cctgaccatc agcggggtcg aggccgggga
      361 tgaggctgac tattactgtc aggtgtggga catgaatagt catcatctat tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01005246             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:10122:12853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005246
VERSION     KCWK01005246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:10122:12853"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..404
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70984.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           96 a          157 c          118 g          109 t
ORIGIN      
        1 acatgggagc ttcagctgtg ggtacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcagc ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct
      181 ggaagcacct ccaacatcgg aagcaataat gtatcctggt accagcagct cccaggaaca
      241 gctcccaaac tcctctttta ttataatgat caacgagcct caggtgtctc tgaccgattc
      301 tcttgctcca agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat
      361 gaggctgatt attactgcgc agcatgggat gataacctga gcggctacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005247             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:12537:13982
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005247
VERSION     KCWK01005247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12537:13982"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70985.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          120 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac ttcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005248             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:10903:3461
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005248
VERSION     KCWK01005248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10903:3461"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..401
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70986.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       402..436
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           89 a          156 c          121 g          108 t
ORIGIN      
        1 acatgggggt gggatctcac gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccccgact
      121 cagactccct ctgtggccgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgata ttgggtatta tcatgctgtg tcttggtacc aacatcatcc aggcaaagcc
      241 cccaaactca tgatttatga ggtcaataaa cggcccgcag gggtctctga tcgcttctct
      301 ggctccaagt ccggcaacac ggcctccctg accatctctg ggctccagac tgaggatgag
      361 gctgattatt actgcagctc atatgcaggc agcaacactt tgttcttcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005249             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:19836:13232
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005249
VERSION     KCWK01005249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19836:13232"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..240
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70987.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       243..277
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>315
                     /gene="IGLC"
BASE COUNT           66 a           86 c           96 g           67 t
ORIGIN      
        1 acatggggga tcacctgtgg gggagacaac attggaagta atagtgtgca ttggtaccag
       61 cagaagccac cgcgggcccc tgtattggtc atctctgttg atagcgaacg gccctcaggg
      121 atccctgagc gattctctgg ttccagatca gggaacaccg ccaccctgac catcagcggg
      181 gtcgaggccg gggatgaggc tgactattac tgtcaggtgt gggataatat ttataaatac
      241 gcggtattcg gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      301 gtcactctct tcccg
//
LOCUS       KCWK01005250             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:18416:7772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005250
VERSION     KCWK01005250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18416:7772"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70988.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          138 c          140 g           97 t
ORIGIN      
        1 acatggggct gactttggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactttacag gctctgcggc ctcctatgag gtgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa aagtgtgcag tggtaccagc agacgccacc gcaggcccct gtactggtca
      241 tttatggtga tagggaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggatagtagt agtaaatatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005251             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:13038:18114
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005251
VERSION     KCWK01005251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13038:18114"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70989.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          155 c          126 g          111 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacagaatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accttctcct gtattggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcaacact cagggacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tactgttgtt catataggag tggaaacact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005252             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:5158:12979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005252
VERSION     KCWK01005252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5158:12979"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..380
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70990.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       394..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           87 a          150 c          117 g          108 t
ORIGIN      
        1 acatggggga ggcagcgctc tcaggacttc tccaccatgg tctgggctct gctcctcctc
       61 accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca gactccctct
      121 gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag cagtgatatt
      181 gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc caaactcatg
      241 atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg ctccaagtct
      301 ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc tgattattac
      361 tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005253             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:3326:16551
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005253
VERSION     KCWK01005253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:3326:16551"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..403
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70991.1"
                     /translation="DYYCSSYAGSNILFF"
     J_segment       408..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          152 c          121 g          113 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc gctctcagga cttctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccccga
      121 ctcagactcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga tattgggtat tatcatgctg tgtcttggta ccaacatcat ccaggcaaag
      241 cccccaaact catgatttat gaggtcaata aacggcccgc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag actgaggatg
      361 aggctgatta ttactgcagc tcatatgcag gcagtaatat tttattcttc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005254             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14463:14174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005254
VERSION     KCWK01005254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14463:14174"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..453
                     /note="immunoglobulin light chain variable region"
     V_region        120..453
     V_segment       120..416
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70992.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       423..453
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           86 a          169 c          133 g          103 t
ORIGIN      
        1 acatggggac ctgcagtgtg gctgcctcag cagagccctg aggagtctgc accatggcct
       61 ggaccccaat cctcctcctc ctcctcactc tcctccttca ctgcacaggg tctctctccc
      121 agcctgtggt gactcagtcg tcctctgcct ctgcctccct gggagcctcg gtcaagctca
      181 cctgcactct gagcggtggg cacagcgact acaccatcgc atggcatcag cagcagcaag
      241 ggaaggcccc tcggtatttg atgtggctta aaagtgatgg cagccacagc aagggggacg
      301 ggatccctga tcgcttctcc ggctccagct ccggggctga gcgctacctc accatctcca
      361 acctccagtc tgaggatgag gctgattatt actgtcagac ctgggagact ggcattcagg
      421 tgttcggcgg agggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca
      481 ctctcttccc g
//
LOCUS       KCWK01005255             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:7230:7337
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005255
VERSION     KCWK01005255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:7230:7337"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70993.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          150 c          117 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccgggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005256             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:24742:11672
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005256
VERSION     KCWK01005256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24742:11672"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..446
                     /note="immunoglobulin light chain variable region"
     V_region        120..446
     V_segment       120..413
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70994.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       414..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>488
                     /gene="IGLC"
BASE COUNT           90 a          157 c          130 g          111 t
ORIGIN      
        1 acatggggga agcgcagctt cagctgtggg tacagaaggc aggactcagg acaatctcca
       61 gcatggcctg gttccctctc gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc
      121 agtctgtgct gactcagcct ccctcagcgt ctgaggccgc caggaagagt gtctccatct
      181 cctgttctgg aagcagctcc aacatcggaa gtcatagtgt ctcctggtac cagcagctcc
      241 caggaacagc tcccaaactc ctcatctatt atagtgatca acgagcctca ggtgtctctg
      301 accgattctc tggctctcag tctggcacgt cagcctccct ggccatcagt gggctccagg
      361 ccgaggatga ggctgattat tactgcgcag catgggatga tagtctgagc ggttacatct
      421 tcggtgctgg gacccggctc gccgtcgtag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCWK01005257             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:15244:11436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005257
VERSION     KCWK01005257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15244:11436"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70995.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          162 c          112 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcggcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaagga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtagtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005258             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20926:8918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005258
VERSION     KCWK01005258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20926:8918"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70996.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       414..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           98 a          158 c          125 g          107 t
ORIGIN      
        1 acatggggga agcgcagctt cagctgtggg tacagaaggc aggactcagg acaatctcca
       61 gcatggcctg gttccctctc gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc
      121 agtctgtgct gactcagcct ccctcagcgt ctgaggccgc caggaagagt gtcaccatct
      181 cctgttctgg aagcagctcc aacatcggaa gtaataatgt gtcctggtac cagcacctcc
      241 caggaacagc tcccaaactc ctcatctact ataatgatca acgaggctca ggtgtctctg
      301 accgattctc tggctccaag tctggcacgt cagcctccct ggccatcagt gggctccaga
      361 ccgaggatga ggctgattat tactgcgcag cgtgggatga tagactgagc agttacatct
      421 tcgctgctgg gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCWK01005259             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:20936:15687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005259
VERSION     KCWK01005259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20936:15687"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70997.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          162 c          109 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg ttccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005260             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:12158:8580
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005260
VERSION     KCWK01005260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12158:8580"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70998.1"
                     /translation="DYYCCSYRSGPTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          159 c          127 g          107 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tggcctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 caacagtgac attggaggtt atagtggcgt ctcctggtac cagcagcact cagggacagc
      241 ccccaaactc ctgatttatg atgtgaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgctgct catataggag tggacccact tgggttttcg gcggagggac
      421 ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005261             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:15129:5707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005261
VERSION     KCWK01005261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15129:5707"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV70999.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          158 c          126 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctccccgga
      241 acagctcccc aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005262             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15015:4734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005262
VERSION     KCWK01005262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15015:4734"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..410
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71000.1"
                     /translation="DYYCGAWDSSLSGYIF"
     J_segment       412..449
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           94 a          159 c          124 g          110 t
ORIGIN      
        1 acatggggaa gctctgcctc agctgtgagc acagaaggca ggacttggga caatcttcat
       61 catgacctgg tcccctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtcctg acgcagccgc cctcagtgtc tgcggcccca gggcagaagg tcaccatctc
      181 ctgctctgga agtagctcca acatcgggag aaattctgtc tcctggtacc agcaggtccc
      241 aggaacggcc cccaaactcc tcagctatga caatgataag cgaccctcag gggtttctga
      301 ccgattctct ggctccaagt ctggttcctc agcctccctg gccatcactg gactccagac
      361 tggagatgag gctgattatt actgcggagc atgggatagc agtctgagtg gttacatttt
      421 cggtgctggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      481 gttcccg
//
LOCUS       KCWK01005263             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:16808:13537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005263
VERSION     KCWK01005263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:16808:13537"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71001.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          144 c          131 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga attgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tctattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005264             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:5203:18315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005264
VERSION     KCWK01005264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:5203:18315"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71002.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          162 c          118 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa accagggagc gctcccaggt
      241 tattcctata ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005265             279 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11227:8829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005265
VERSION     KCWK01005265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 279)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11227:8829"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..241
                     /note="immunoglobulin light chain variable region"
     V_region        8..241
     V_segment       8..204
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <166..>213
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71003.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       207..241
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        242..>279
                     /gene="IGLC"
BASE COUNT           52 a           87 c           82 g           58 t
ORIGIN      
        1 acatgggatg tgcactggta ccagcagaag ccagcgcagg cccctgtgtt ggtcatctat
       61 gctgatacca gacggccctc agggatccct gagcgattct ctggctccaa ctcagggaac
      121 accgccaccc tgaccatcac cggggtcgag gccgggtatg aggctgacta tttctgtcag
      181 gtttgggacg atagtagtga tcatccggta ttcggcggag ggacccggct gaccgtccta
      241 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005266             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:16537:22650
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005266
VERSION     KCWK01005266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16537:22650"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71004.1"
                     /translation="DYFCQVYDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          160 c          125 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga ggccagggag cgctcccagg
      241 ttattcctgt attactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaggtaac acagcgtttt tgctcatctc tggactccag
      361 cctgaggacg aggccgatta tttctgtcag gtgtatgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01005267             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:23797:12529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005267
VERSION     KCWK01005267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:23797:12529"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71005.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          161 c          124 g          105 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atcccctgca ctggaaccaa
      181 cagtgacatc ggtgattatg actttgtctc ctggtaccaa caacatccag gcacagcccc
      241 cagactcgtg atttatgagg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggc ctccagcctg aggacgaggc
      361 tgattattac tgcagctcat atgcaggcag cgacactttc gtgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005268             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:10525:11752
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005268
VERSION     KCWK01005268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10525:11752"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..385
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71006.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       394..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           91 a          149 c          117 g          105 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gtatctgggg cccccggaca gagggtcacc atctcctgca ttagcagcag ctccaacatc
      181 ggggcggctt attatgtatc ctggtaccaa cagttcccag gaacagcccc caaactcctc
      241 atctttgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggtccctcag cctccctgac catcactgga ctccaatctg aggatgaggg tgattattac
      361 tgtttagcat gggataccag cctgaattgg atcttcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005269             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:20621:11999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005269
VERSION     KCWK01005269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20621:11999"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71007.1"
                     /translation="DYYYYSADSSGNWVF"
     J_segment       384..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           95 a          136 c          121 g          106 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catagcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct cttcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattac
      181 caaaaaaata tgcttcttgg ttccagctga agccaggcca gtcccctgtg atggtcatct
      241 ttgaggacag caaacggccc tctgggatcc ctgagagatt ctttggctcc agtttaggga
      301 cagtggccac cttgactata attggggccc aggtggagga tgaagatgac tactactatt
      361 actcagcaga cagtagtggt aattgggtat tcgccggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005270             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:10921:10246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005270
VERSION     KCWK01005270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10921:10246"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..274
                     /note="immunoglobulin light chain variable region"
     V_region        8..274
     V_segment       8..238
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>246
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71008.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       242..274
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        275..>312
                     /gene="IGLC"
BASE COUNT           68 a           89 c           94 g           61 t
ORIGIN      
        1 acatggggga tcacctgtgg gggagacaac attggaacta aaactgtgca ctggtaccag
       61 cagaagccac cgcagggccc tgtattggtc atctttgctg acagtaaacg gccctcaggg
      121 atccctgagc gattctctgg ctccaactca gggaacaccg ccaccctgac catcagcggg
      181 gtcgaggccg gggatgaggc tgactattac tgtcaggtgt gggacagtag tagtaaatgg
      241 atattcggcg gggggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      301 actctcttcc cg
//
LOCUS       KCWK01005271             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:24446:6086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005271
VERSION     KCWK01005271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24446:6086"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    84..432
                     /note="immunoglobulin light chain variable region"
     V_region        84..432
     V_segment       84..392
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71009.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       395..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           94 a          157 c          114 g          105 t
ORIGIN      
        1 acatggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc ctgctcctct
       61 ctcaccgcac aggttccctc tccaagccta tgctgactca gccggcctcc ctctcagcat
      121 ctcctggagc atcagccagt ctcacatgca ccttcggcgg tggcatcaat gttgctggct
      181 accacataca ctggtaccaa cagaagccag ggagtccccc ccggtatctt ctgaggtaca
      241 aatcagactc agataagggc cagggctctg gagtcaccag ccgcttctct ggatccaaag
      301 atgcttcagc gaacacaggg attttacgca tctctgggct ccagtctgag gatgaggctg
      361 actattactg tgccattggg cacagcagcg gtgattacat cttcggtgct gggacccgac
      421 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005272             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:13226:17374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005272
VERSION     KCWK01005272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13226:17374"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..276
                     /note="immunoglobulin light chain variable region"
     V_region        8..276
     V_segment       8..241
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71010.1"
                     /translation="DYYCQVWDSDSKWVF"
     J_segment       243..276
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        277..>317
                     /gene="IGLC"
BASE COUNT           68 a           93 c           97 g           59 t
ORIGIN      
        1 acatgggggc caggatcacc tgtggcgggg acagccttgg aacaaaatat gtgcactggt
       61 accagcagaa gccaacgcag gcccctgtgg tggtcatcta tgctgataat aaacggccct
      121 cagggatccc tgagcgattc tctggctcca actcagggaa caccgccacc ctgaccatca
      181 gcagggtcga ggccggggat gaggctgact attactgtca ggtgtgggac agtgatagta
      241 agtgggtctt cggcggaggg acccggctaa ccgtcccagg tcagcccaag gctgccccct
      301 cggtcactct cttcccg
//
LOCUS       KCWK01005273             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:21955:12116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005273
VERSION     KCWK01005273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21955:12116"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..400
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71011.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       403..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           91 a          162 c          112 g          110 t
ORIGIN      
        1 acatggggca gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccca gcctgtgctg acccagccaa cctccctctc
      121 agcatctccg ggagcatcag ccagactcag ctgcaccttg agcagtggca ccaatgttgg
      181 tagttacagg atattctggt accagcagaa gccagggagt cctccccggt accttctgta
      241 ctactactca gactcaacta agcaccaggg ctctggagtc cccagccgct tctctggatc
      301 caaagatgct tcagccaatg cagggctttt actgatctct gggctccagt ctgaagatga
      361 ggctgactat tactgtgcca tatggcacag cagcgcttct tgcatcttcg gtcctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005274             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14808:11194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005274
VERSION     KCWK01005274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14808:11194"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71012.1"
                     /translation="DYYCQVFDDSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          160 c          119 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgttctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata caacgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacga tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005275             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:28017:11738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005275
VERSION     KCWK01005275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:28017:11738"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..395
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71013.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       396..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           88 a          154 c          124 g          104 t
ORIGIN      
        1 acatgggggg ggtacagaag gcaggactca ggacaatctc cagcatggcc tggttccctc
       61 tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg ctgactcagc
      121 ctccctcagc gtctgaggcc gccaggaaga gtgtctccat ctcctgttcg ggaagcagct
      181 ccaacatcgg aagtcatagt gtctcctggt accagcaact cccaggaaca gctcccaaac
      241 tcctcatcta ttatagtgat caacgagcct caggtgtctc tgaccgattc tctggctccc
      301 agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat gaggctgatt
      361 attactgcgc ggcatgggat gatagcctga gcggttacat cttcggtggt gggacccggc
      421 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005276             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:10286:16298
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005276
VERSION     KCWK01005276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10286:16298"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71014.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          165 c          121 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgttctggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcagctgga acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005277             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:6675:19578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005277
VERSION     KCWK01005277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6675:19578"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..385
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71015.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       394..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           90 a          152 c          116 g          104 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gcatctgggg cccccggaca gagggtcacc atctcctgca ttagcagcag ctccaacatc
      181 ggggcggctt attatgtatc ctggtaccaa cagttcccag gaacagcccc caaactcctc
      241 atctttgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggtccctccg cctccctgac catcactgga ctccaatctg aggatgaggc tgattattac
      361 tgtttagcat gggataccag cctgaattgg atcttcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005278             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:10090:16811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005278
VERSION     KCWK01005278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10090:16811"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71016.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       394..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          157 c          119 g          101 t
ORIGIN      
        1 acatgggggc acaggaggca gcactcagga cagtctccag catggcctcg tctcctctcc
       61 tcctcaccct tctcattcac tgcacagggt cctgggccca gtctgtgctg acacagccgc
      121 cctcagtgtc tggggcccca gggcagaggg tcaccatctc ctgcactggg agcagctcca
      181 acattggagg ttattatata tcctggtacc agcagctccc aggaacggcc cccaaactcc
      241 tcgtctatga caataataag cgaccctcag gggtttctga ccgattctct ggctccaagt
      301 ctggttcctc agccaccctg accatcactg ggctccagac tgaggatgag gctgattatt
      361 actgccagtc ctatgacagc agtctgagtg ctcgggtatt cggcggaggg acccggctaa
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005279             403 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:3808:9635
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005279
VERSION     KCWK01005279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 403)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:3808:9635"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..365
                     /note="immunoglobulin light chain variable region"
     V_region        20..365
     V_segment       20..328
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <296..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71017.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       329..365
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>403
                     /gene="IGLC"
BASE COUNT           81 a          130 c          102 g           90 t
ORIGIN      
        1 acatgggggt tccctctccc agcctgtgct gactcagcca ccctccctgt ctgcatcccc
       61 gggagcatcg gccagactcc cctgcaccct gagcagtgac ctcagtgttg gtaataaaaa
      121 catgtactgg taccaacaga agccagggag cgctcccagg ttattcctgt actactactc
      181 cgactcagac aagcagctgg gacctggggt ccccaatcga gtctctggct ccaaggagac
      241 ctcaactaac acagcgtttt tgctcatctc tgggctccag cctgaggacg aggccgatta
      301 ttactgtcag gtgtttgaca gtagtgctgt gttattcgga ggagggaccc gactgaccgt
      361 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005280             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:10504:13073
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005280
VERSION     KCWK01005280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10504:13073"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71018.1"
                     /translation="DYYCAAWDDRLTGYVF"
     J_segment       415..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          159 c          124 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cgggaccaat agtgtatcct ggtaccagct gctcccagaa
      241 acggctccca aactcctcat ctattataat aatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatcgcc tgaccggtta cgtattcggt
      421 gttgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005281             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:5813:12340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005281
VERSION     KCWK01005281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5813:12340"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71019.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          161 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggacgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005282             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:11612:10999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005282
VERSION     KCWK01005282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11612:10999"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..433
                     /note="immunoglobulin light chain variable region"
     V_region        101..433
     V_segment       101..397
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71020.1"
                     /translation="DYYCQTWDTGIVFF"
     J_segment       398..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>472
                     /gene="IGLC"
BASE COUNT           90 a          162 c          121 g           99 t
ORIGIN      
        1 acatggggga gcagagccct gaggagtctg caccatggcc tggaccccaa tcctcctcct
       61 cctcctcact ctcctccttc actgcacagg gtctctctcc cagcctgtgc tgactcagtc
      121 gccctctgcc tctgcctccc tgggagcctc ggtcaaactc acctgcactc tgaacagtgg
      181 gcacagcagc tacaccatcg catggcatca gcagcagaaa gggaaggccc cccggtattt
      241 gatgtggctt aaaactgatg gcagccataa caagggggac gggatccctg atcgcttcgc
      301 aggctccagc tccggggctg agcgctacct caccatctcc aacctccagt ctgaggatga
      361 ggctgattat tactgtcaga cctgggatac tggcattgtg ttcttcggag gagggacccg
      421 gctgaccgtc ctaagtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005283             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:12910:14903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005283
VERSION     KCWK01005283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12910:14903"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71021.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          158 c          117 g          112 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgccc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaagctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtcttata atgctgtgtc ttggtaccaa cagcgtccag gcaaagcccc
      241 ccaactcata gtttttgagg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaactct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgctgctcat atgtaggcag caacacttac atcttcgatg ttgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01005284             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:20271:8204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005284
VERSION     KCWK01005284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20271:8204"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71022.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          156 c          125 g          114 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cacttcacag ttccagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggagat tattttgtgc agtggtacca gcaccttcca
      241 ggaacggccc ccaaactcct catctatgaa aataataagc ggccctcagg gatttctgat
      301 cgattctctg gctcccagtc tggaacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtttgattgc tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01005285             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:6662:8980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005285
VERSION     KCWK01005285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6662:8980"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71023.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          148 c          129 g           97 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gtactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact attgatcacg gcttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005286             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18065:23489
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005286
VERSION     KCWK01005286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18065:23489"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..410
                     /note="immunoglobulin light chain variable region"
     V_region        101..410
     V_segment       101..387
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71024.1"
                     /translation="DYYCQSADSSGNHWLF"
     J_segment       388..410
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>462
                     /gene="IGLC"
BASE COUNT          102 a          135 c          128 g           97 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg ccagtgtgcc caggacagac ggccaggatc acctgctctg gagaagtact
      181 ggcaaaaaaa tctgctcagt ggttccagca gaagccaggc caggcccctg tgttggtgat
      241 tcataaagac attgagaggc cctcagggat ccctgaccga ttctctaggt ccactccagg
      301 gacaaaagtt accttgacca gcaggggggc caggcagaag atgaggctga ctattactgt
      361 caatcagcag acagcagtgg taatcattgg ctattcggcg gagggacccg tctaagcgtc
      421 ctgggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005287             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:21698:11394
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005287
VERSION     KCWK01005287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:21698:11394"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71025.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          138 c          134 g          103 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttccca
//
LOCUS       KCWK01005288             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:17367:10709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005288
VERSION     KCWK01005288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17367:10709"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..410
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71026.1"
                     /translation="VYYCGAWDSSLSGYIF"
     J_segment       412..449
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           95 a          157 c          125 g          110 t
ORIGIN      
        1 acatggggaa gctctgcctc agctgtgagc acagaaggca ggacttggga caatcttcat
       61 catgacctgg tcccctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tacggcccca gggcagaagg tcaccatctc
      181 ctgctctgga agtagctcca acatcgggag aaattctgta tcctggtacc agcaggtccc
      241 aggaacggcc cccaaagtcc tcatctatga caataataag cgcccctcgg gggtttctga
      301 ccgattctct ggctccaagt ctggtacctc agcctccctg gccatcactg gactccaggc
      361 tggagatgag gctgtttatt actgcggagc atgggatagc agtctgagtg gttacatctt
      421 cggtgatggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      481 gttcccg
//
LOCUS       KCWK01005289             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:18456:10069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005289
VERSION     KCWK01005289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18456:10069"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..398
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71027.1"
                     /translation="DYYCMIWHTNLFVLF"
     J_segment       404..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          153 c          116 g          117 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgcgcagt ggcatcagtg
      181 ttggtagtta caggatcttc tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gataaacacc agggatctgg agtccccagc cgcttttctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaccaatct ttttgtgtta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005290             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:21924:15689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005290
VERSION     KCWK01005290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21924:15689"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71028.1"
                     /translation="DYYCQSTDTSGNYIF"
     J_segment       386..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT          104 a          131 c          123 g          102 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctggggcc tcctttgagc tgacacaggc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gaggaatact
      181 ggcaaaaaaa tatgctcagt ggttgcagca gaagccaggc caggcccctg tgttggtaat
      241 atataaagac agtgagaggc cctcagggat ccctgaacga ttctctagtt ccagttcagg
      301 gacaacagtt gccttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcaaca gacaccagtg gtaattacat cttcggtgct gggacccggc tcaacgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005291             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:21224:2439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005291
VERSION     KCWK01005291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:21224:2439"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71029.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       413..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           89 a          154 c          131 g          114 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgtactgg gggcagctcc aacattggag gttattatgt gcagtggtac cagcagcttc
      241 cagggacggc ccccaaactc ctcatctatg aaaatgataa acgaccctca ggggtttctg
      301 atcgattctc tggctcccag tctgattcct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagcttgagt gttgtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01005292             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:15846:13159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005292
VERSION     KCWK01005292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:15846:13159"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71030.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       405..439
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           91 a          160 c          113 g          113 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgacccagcc aacctccctc
      121 tcagcatctc cgggagcatc agtcagactc agctgcacct tgagcagtgg catcaatgtt
      181 ggttcttaca ccatattctg gtaccagcag aagccaggga gtcctccccg gttccttctg
      241 tactactact cagactcaaa taatcaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcagccaa tgcaggcctt ttactgatct ctgggctcca gtctgaagat
      361 gaggctgact attactgtgc catgtggcac agcagcgctt atgccttatt cggaggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005293             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:8746:15239
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005293
VERSION     KCWK01005293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:8746:15239"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71031.1"
                     /translation="DYSCQVWDSESDYYIF"
     J_segment       391..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          146 c          134 g           96 t
ORIGIN      
        1 acatgggggc tgggtctcag gaggcagcat tgacggtgcc tcagccatgg cctggaccct
       61 tctcctcctc ggcctcctcg ctcactgcac aggctctgcg acctcctttg agctgactca
      121 gccaccctcg gtgtcagcgg cctcaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaatt aaatttgtcc actggtacca gcagaagcca gcgcaggccc ctgtgaaggt
      241 catctatgct gatgacaaac ggccctcagg gatccctgag agattctctg gctccaattc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactattc
      361 ctgtcaggtg tgggacagtg agagtgatta ttacatcttc ggtgctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005294             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:13264:11099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005294
VERSION     KCWK01005294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13264:11099"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71032.1"
                     /translation="DYYCQVYDSGANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          165 c          124 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggct ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagcgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tggtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005295             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:11449:8836
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005295
VERSION     KCWK01005295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11449:8836"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..400
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71033.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           91 a          153 c          121 g          110 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctcctct
       61 cctcctcacc cttctcattc acttcacagt tccagggtcc tgggcccagt ctgtgctgac
      121 gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag
      181 cagctccaac attggagatt attttgtgca gtggtaccag caccttccag gaacggcccc
      241 caaactcctc atctatgaaa ataataagcg accctcaggg atttctgatc gattctctgg
      301 ctcccagtct ggaacctcag cctccctgac catcactgga ctccagtctg aggatgaggc
      361 tgattattac tgccagtcct atgacagcag tttgattgct gtgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005296             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:5138:14332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005296
VERSION     KCWK01005296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5138:14332"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71034.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       401..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           96 a          151 c          113 g          116 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcatctcc tggagcatca gccagactca cctgcacctt gaacagtggc atcagtgttg
      181 gtaattacag gatattctgg taccaccaga agccagggag tcctccccgg tatcttctga
      241 actaccacac agactcagat attcatcagg ggtctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcagggattt tactcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtatg atttggcaca acaatgctta ttgggttttc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005297             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:21903:14277
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005297
VERSION     KCWK01005297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21903:14277"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..430
                     /note="immunoglobulin light chain variable region"
     V_region        105..430
     V_segment       105..395
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71035.1"
                     /translation="DYYCQSADGNYRVF"
     J_segment       396..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>469
                     /gene="IGLC"
BASE COUNT           86 a          162 c          121 g          100 t
ORIGIN      
        1 acatgggggt gactcagaaa gcagagcctg gggcgtctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaacttgtgt tcactcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcattgg
      181 caacattgac agtgaatatg tgcagtggta ccagcagcgc ccgggcagtg cccccaccac
      241 actgatttac aaagatagtc aaagaccctc tggggtccct gaccggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcgc catctctggg ctacagtctg aggacgaggc
      361 tgactactac tgtcagtctg ctgatggcaa ctacagggtc ttcggcggag ggacccggct
      421 aaccgtccta agtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005298             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:15786:22610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005298
VERSION     KCWK01005298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15786:22610"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71036.1"
                     /translation="GYYCQVWDISSDHVLF"
     J_segment       390..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          140 c          139 g           97 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctttgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtga acttgtgaac tggtaccaac agaggccacc gcaggcccct gtgctggtca
      241 tctatgctga tagcgaacgg ccctcaggga tccctgaacg aatctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct ggctattact
      361 gtcaggtgtg ggacattagt agtgatcatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005299             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:11981:5022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005299
VERSION     KCWK01005299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11981:5022"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..455
                     /note="immunoglobulin light chain variable region"
     V_region        125..455
     V_segment       125..418
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71037.1"
                     /translation="DYYCAAWDDRLTGYVF"
     J_segment       425..455
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           92 a          158 c          133 g          110 t
ORIGIN      
        1 acatgggggg ggtgaagcgc agcttcagct gtgggtacag aaggcaggac tcaggacaat
       61 ctccagcatg gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg
      121 ggcccagtct gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac
      181 catctcctgt tctggaagca gctccaacat cgggagcaat agtgtatcct ggtaccagct
      241 gctcccagaa acggctccca aactcctcat ctattataat aatcggcgag cctcaggtgt
      301 ctctgaccga ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct
      361 ccagaccgag gatgagggtg attattactg cgcagcatgg gatgatcgcc tgaccggtta
      421 cgtgttcggt gttgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt
      481 cactctgttc ccg
//
LOCUS       KCWK01005300             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:22320:4610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005300
VERSION     KCWK01005300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:22320:4610"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71038.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          156 c          127 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc cgcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaaggaat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg catgtcagcc tccctggcca tcagcgggct ccagaccgag
      361 gatgagggtg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005301             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:22287:19634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005301
VERSION     KCWK01005301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22287:19634"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71039.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          156 c          116 g          115 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaagctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc ttctcctgca ctggaaccgg
      181 cagtgatttt gggtcttata atgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 ccaactcata atttttgagg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgctgctcat atgtaggcag caacacttac atcttcgatg ttgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01005302             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:18717:8613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005302
VERSION     KCWK01005302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18717:8613"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71040.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          153 c          120 g          102 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgagctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctcct gctctggaag cagctccaat
      181 attggaagta attctgtata ctggtaccag cagttcccag gaacggcccc caaactcctc
      241 atctattata gtaatcagcg accctcaggg gtccctgacc gagtctctgg ctctaagtcg
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgacag cctgagaagt ccgctattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005303             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18086:17756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005303
VERSION     KCWK01005303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18086:17756"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71041.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          144 c          132 g           95 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gaactgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc agcagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgatagtaaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt ttgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005304             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13332:5703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005304
VERSION     KCWK01005304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13332:5703"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..433
                     /note="immunoglobulin light chain variable region"
     V_region        88..433
     V_segment       88..396
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71042.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           92 a          158 c          111 g          110 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttga gcagtggcaa tgttggtagt
      181 tacagcatat tctggtacca gcagaagcca gggagtcctc cccggtacct tctttactac
      241 tactcagact caagtaacca ccaggactct ggagtcccca gccgcttctc tggatcgaaa
      301 gatgcttcag ccaatgcagg gcttttactg atctctgggc tccagtctga agatgaggct
      361 gactattact gtgccacatg gcacagcagc gcttcttaca tcttcggtgg tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01005305             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:16749:4342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005305
VERSION     KCWK01005305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16749:4342"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71043.1"
                     /translation="DYYCAMWHSSASYFF"
     J_segment       405..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>479
                     /gene="IGLC"
BASE COUNT           90 a          164 c          111 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca tctaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaagga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccag ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005306             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:24836:9731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005306
VERSION     KCWK01005306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24836:9731"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    27..357
                     /note="immunoglobulin light chain variable region"
     V_region        27..357
     V_segment       27..313
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <285..>329
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71044.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       320..357
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        358..>395
                     /gene="IGLC"
BASE COUNT           76 a          125 c           98 g           96 t
ORIGIN      
        1 acatgggggg cacaggatcc tgggctcaag ctgccccgac tcagcctccc tctgtgtccg
       61 ggtctcctgg gcagtcggtc accatctcct gcactggaac cagcagtgat attgggtctt
      121 ataatgctgt gtcttggtac caacaacatc caggcaaagc cccccaactc ataatttttg
      181 aggtcaataa gcggccctca ggggtctctg atcgcttctc tggctccaag tctggcaaca
      241 cggcctccct gaccatttct gggctccagg ctgaggatga ggctgattat tactgctgct
      301 catatgtagg cagcaacact tacatcttcg atgttgggac ccggctcacc gtcctaggtc
      361 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005307             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:5435:15722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005307
VERSION     KCWK01005307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5435:15722"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71045.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          148 c          131 g           98 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctccgatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt aagagtgtgc actggtacca acacaagcca ccgcaggccc ctatcctggt
      241 catctattat tataccgaac ggccctcggc gatccctgag cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacacta ctattgatca tggctttttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005308             427 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:17224:13974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005308
VERSION     KCWK01005308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 427)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17224:13974"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..389
                     /note="immunoglobulin light chain variable region"
     V_region        93..389
     V_segment       93..352
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <317..>361
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71046.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       353..389
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        390..>427
                     /gene="IGLC"
BASE COUNT           82 a          142 c          100 g          103 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagccaga ctcagctgca ccttgagcag
      121 tggcaatgtt ggcagttaca gcatattctg gtaccagcag aagccaggga gtcctccccg
      181 gttccttctt tactactact cagactcaag taaccaccag gactctggag tccccagccg
      241 cttctctgga tcgaaagatg cttcagccaa tgcagggctt ttactgatct ctgggctcca
      301 gtctgatgat gaggctgact attactgtgc cacatggcac agcagcgctt cttacatctt
      361 cggtcctggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      421 gttcccg
//
LOCUS       KCWK01005309             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:13712:11556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005309
VERSION     KCWK01005309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13712:11556"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71047.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          157 c          121 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc aacgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca actccaacat cggaagttat aatgtgtcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcggcatgg gatgatagcc ttagcggtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005310             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:19583:9324
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005310
VERSION     KCWK01005310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19583:9324"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..431
                     /note="immunoglobulin light chain variable region"
     V_region        95..431
     V_segment       95..388
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71048.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       394..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           94 a          152 c          117 g          106 t
ORIGIN      
        1 acatggggga caggaggcag cactcaggac agtctccagc atggcctggt ctctccttct
       61 cactctgctg gttcactgca cagggtcctg ggcccagtct gtgctgacgc agccgccctc
      121 agcatctggg gcccccgggc agagggtcac catctcctgc actgggagca gctccaacat
      181 cggggcgggt tattatgtat cctggtacca gcagttccca ggaacagccc ccaaactcct
      241 catctatgaa aataataaac gaccctcagg ggtttctgac cgattctctg gctccaagtc
      301 tggtacctca gcctccctga ccatcactgg actccaatct gaggatgagg ctgattatta
      361 ctgctcagca tgggatagca gcctgagtat caattacatc ttcggttctg ggacccgtct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005311             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:19408:14288
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005311
VERSION     KCWK01005311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19408:14288"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71049.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          162 c          122 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgttg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005312             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:18599:3413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005312
VERSION     KCWK01005312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18599:3413"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71050.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          150 c          135 g           95 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaac taaatatgtg cactggtacc agcagaagcc agcgcaggcc cctgtgttgg
      241 tcatctatgc tgataccaga cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcaccg gggtcgaggc cgggtatgag gctgactatt
      361 tctgtcaggt ttgggacgat agtagtgatc atccggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005313             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:21934:3021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005313
VERSION     KCWK01005313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:21934:3021"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71051.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          164 c          120 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatattgg caataaaaac atgtactggt accagcagaa gccagggagc gctcccaagt
      241 tcttcctgta ctactactcc gactcagaca tgcagctggg acctggggtc cccagtcgag
      301 tctctggctc caaggagccc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005314             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:17028:4928
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005314
VERSION     KCWK01005314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17028:4928"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..423
                     /note="immunoglobulin light chain variable region"
     V_region        103..423
     V_segment       103..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71052.1"
                     /translation="DYYCQVWDSSSRYILF"
     J_segment       397..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>465
                     /gene="IGLC"
BASE COUNT           94 a          140 c          131 g          100 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctctga cctgactcag
      121 ccaccctcag tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggtgacaac
      181 attggaagta ataatgtaca ctggtaccag cagaagccag cgcaggcccc tatgttggtc
      241 atctatggtg gtagtaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtagatac attttgttcg gaagaggcac caggctgacc
      421 gtcatcggtc accccaaggc ttctcccttg gtcactctgt ttccg
//
LOCUS       KCWK01005315             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:22255:4148
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005315
VERSION     KCWK01005315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:22255:4148"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71053.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          159 c          124 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagag gccagggagt gctcccaggt
      241 tattcctgta ttactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaggtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005316             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:10438:4315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005316
VERSION     KCWK01005316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10438:4315"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71054.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          158 c          120 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagatacag atcagactca gataagggcc agggctctgg agtccccagc cggttctctg
      301 gatccaaaga tgctgcagcg aacacaggga ttttacgcat ctctgggctc cagtttgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tccttacttc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005317             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:16697:12628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005317
VERSION     KCWK01005317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16697:12628"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..441
                     /note="immunoglobulin light chain variable region"
     V_region        115..441
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71055.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>483
                     /gene="IGLC"
BASE COUNT           88 a          156 c          128 g          111 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagtc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cgtaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005318             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:15664:19733
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005318
VERSION     KCWK01005318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15664:19733"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71056.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          162 c          108 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt tctgacccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005319             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:15778:14082
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005319
VERSION     KCWK01005319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15778:14082"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71057.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          162 c          124 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005320             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:17931:15359
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005320
VERSION     KCWK01005320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17931:15359"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71058.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          144 c          133 g           94 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca cagactctgc gacctcctat gaactgactc
      121 agtcaccctc agtgtcagcg gcctcgggac agccggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc agcagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgatagtaaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005321             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:23238:3122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005321
VERSION     KCWK01005321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:23238:3122"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..439
                     /note="immunoglobulin light chain variable region"
     V_region        94..439
     V_segment       94..403
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71059.1"
                     /translation="DYYCAVWSSSAYIF"
     J_segment       404..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           83 a          157 c          119 g          118 t
ORIGIN      
        1 acatggggga ctgcggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctg tcacagcctg tgctgactca gccggcctcc
      121 ctctcagcat ctcctggagc atcagtcaga ctcacctgca ccttgcgcac tggcctcaat
      181 gttggtggct actacatatt ctggtaccag cagaagccag ggagtcctcc ccggttcctt
      241 ctgaattact actcagactc aaatcagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgtttcagc caatgcaggg cttttactga tctctgggct ccagtctgag
      361 gatgaggctg actattactg tgccgtttgg tccagcagcg cttacatctt cggtggtggg
      421 actcggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01005322             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:22158:14365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005322
VERSION     KCWK01005322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22158:14365"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71060.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       413..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           92 a          155 c          123 g          111 t
ORIGIN      
        1 acatgggggt ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct ctccttctca ctctgctggt tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag catctggggc ccccggacag agggtcacca tttcctgcat
      181 tagcagcagc tccaacatcg gggcggctta ttatgtatcc tggtaccaac agttcccagg
      241 aacagccccc aaactcctca tctttgaaaa taataagcga ccctcagggg tttctgaccg
      301 attctctggc tccaagtctg gtccctcagc ctccctgacc atcactggac tccaatctga
      361 ggatgaggct gattattact gtttagcatg ggataccagc ctgaattgga tcttcggcgg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01005323             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:23856:9813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005323
VERSION     KCWK01005323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:23856:9813"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71061.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          149 c          122 g          114 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gttcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatgtt gggtattata acgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 caaactcatg atttatgacg tcattaagcg gccctcaggg gtttctgatc gcttctctgg
      301 ctccaagtct ggcgacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag aaataatttt ttattcggag gagggacctg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005324             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:12888:23199
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005324
VERSION     KCWK01005324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12888:23199"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71062.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          154 c          122 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgccgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005325             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:23587:16783
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005325
VERSION     KCWK01005325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23587:16783"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71063.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       398..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           86 a          155 c          123 g          105 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcatctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagtagtgg
      181 cagcattgac aacggctttg tgtactggta ccagcagcgg ccgggcagcg ctcccaccac
      241 tgtgatttac aaagataacc aaagaccctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctgga ctgaaatctg aggacgaggc
      361 tgactattac tgtcagtctt atgacagcag cagtgtatta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005326             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:12805:6236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005326
VERSION     KCWK01005326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12805:6236"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71064.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          129 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cagtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005327             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:15183:4656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005327
VERSION     KCWK01005327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15183:4656"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71065.1"
                     /translation="DYYCQSVDSSGNHPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          106 a          131 c          123 g          103 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tcttcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatgctcagt ggttccagca gaagccaggc caggcccctg tgttggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgaacga ttctctagtt ccagttcagg
      301 gacaacagtt accttgacca tcagtggggc ccaggtagaa gatgaggctg actattactg
      361 tcaatcagta gacagcagtg gtaatcatcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005328             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:11177:19430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005328
VERSION     KCWK01005328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11177:19430"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..303
                     /note="immunoglobulin light chain variable region"
     V_region        6..303
     V_segment       6..264
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71066.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       273..303
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           71 a          109 c           84 g           77 t
ORIGIN      
        1 acatgggggc ccccggacag agggtcacca tctcctgcat tagcagcagc tccaacatcg
       61 gggcggctta ttatgtatcc tggtaccaac agttcccagg aacagccccc aagctcctca
      121 tctatgaaaa taataagcga ccctcagggg tttctgaccg attctctggc tccaagtctg
      181 gtccctcagc ctccctgacc atcactggac tccagtctga ggatgaggct gattattact
      241 gtttagcatg ggataccagc ctgaattgga tcttcggcgg agggacccgg ctgaccgtcc
      301 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005329             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:12418:11903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005329
VERSION     KCWK01005329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12418:11903"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..225
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <197..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71067.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       239..269
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           66 a           89 c           79 g           73 t
ORIGIN      
        1 acatggggga accagcagtg atattgggta ttatcatgct gtgtcttggt accagcatca
       61 tccaggcaaa gcccccaaac tcatgattta tgaggtcaat aaacggcccg caggggtctc
      121 tgatcgcttc tctggctcca agtctggcaa cacggcctcc ctgaccatct ctgggctcca
      181 gactgaggat gaggctgatt attactgtag ctcatatgca ggcagcaaca gtttattctt
      241 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCWK01005330             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:22848:5468
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005330
VERSION     KCWK01005330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22848:5468"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71068.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           93 a          162 c          108 g          110 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtctcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtact gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gaccagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc caggcgcttc tctggatcga
      301 aagatgcttc agccaatgca ggccttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt gctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005331             294 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:24161:11005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005331
VERSION     KCWK01005331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 294)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:24161:11005"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..256
                     /note="immunoglobulin light chain variable region"
     V_region        7..256
     V_segment       7..213
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <178..>228
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71069.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       219..256
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        257..>294
                     /gene="IGLC"
BASE COUNT           64 a           88 c           70 g           72 t
ORIGIN      
        1 acatgggggg cgggttatta tgtatcctgg taccagcagt tcccaggaac agcccccaaa
       61 ctcctcatct atgaaaataa taagcgaccc tcaggggttt ctgaccgatt ctctggctcc
      121 aagtctggta cctcagcctc cctgaccatc actggactcc aatctgagga tgaggctgat
      181 tattactgct cagcatggga tagcagcctg agtattaatt acatcttcgg tggtgggacc
      241 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005332             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:12917:14125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005332
VERSION     KCWK01005332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12917:14125"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71070.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       391..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          139 c          136 g          102 t
ORIGIN      
        1 acatggggtg actttgggaa gcagccttgg cggtgcctca gccatggccg ggacccttct
       61 cctcctcggc ctccttgctc actttacagg ctctgtggcc tcctatgagt tgcctcagcc
      121 acgctcagtg tccgtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaat agtgtgcatt ggtaccagca gaagccaccg cgggcccctg tattggtcat
      241 ctctgttgat agcgaacggc cctcagggat ccctgagcga ttctctggtt ccagatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gataatattt ataaatacgc ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005333             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:13011:14185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005333
VERSION     KCWK01005333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13011:14185"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71071.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          158 c          127 g          105 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ccccagactg aggacgaggc
      361 tgattattac tgttgctcat ataggagtgg aaacacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005334             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:17835:6185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005334
VERSION     KCWK01005334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17835:6185"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71072.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           92 a          162 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggagtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005335             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:11699:9892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005335
VERSION     KCWK01005335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:11699:9892"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71073.1"
                     /translation="DYYCQVWDISSEHVLF"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          142 c          137 g           99 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gcctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcggtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaggtg cagttgtgaa ttggtaccac cagaagccac cgcaggcccc tgtactggtc
      241 atctatgctg atagcgatcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacattag tagtgaacat gtattattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005336             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:23893:14079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005336
VERSION     KCWK01005336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:23893:14079"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..444
                     /note="immunoglobulin light chain variable region"
     V_region        118..444
     V_segment       118..411
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71074.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       412..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>486
                     /gene="IGLC"
BASE COUNT           89 a          157 c          129 g          111 t
ORIGIN      
        1 acatggggag cgcagcttca gctgtgggta cagaaggcag gactcaggac aatctccagc
       61 atggcctggt tccctctcgt cctcaccctc ctcactcact gtgcagggtc ctgggcccag
      121 tctgtgctga ctcagcctcc ctcagcgtct gaggccgcca ggaagagtgt ctccatctcc
      181 tgttctggaa gcagctccaa catcggaagt catagtgtct cctggtacca gcagctccca
      241 ggaacagctc ccaaactcct catctattat agtgatcaac gagcctcagg tgtctctgac
      301 cgattctctg gctctcagtc tggcacgtca gcctccctgg ccatcagtgg gctccaggcc
      361 gaggatgagg ctgattatta ctgcgcagca tgggatgata gtctgagcgg ttacatcttc
      421 ggtgctggga cccggctcgc cgtcgtaggt cagcccaagg cttcccccac ggtcactctg
      481 ttcccg
//
LOCUS       KCWK01005337             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:18173:8452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005337
VERSION     KCWK01005337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18173:8452"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..416
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71075.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       418..454
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           98 a          159 c          125 g          110 t
ORIGIN      
        1 acatgggggg gtgaagcgca gcttcagctg tgggtacaga aggcaggact caggacaatc
       61 tccagcatgg cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg
      121 gcccagtctg tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc
      181 atctcctgtt ctggaagcac ctccaacatc ggaagcaata atgtatcctg gtaccagcag
      241 ctcccaggaa cagctcccaa actcctcttt tattataatg atcaacgagc ctcaggtgtc
      301 tctgaccgat tctcttgctc caagtctggc acgtcagcct ccctggccat cagtgggctc
      361 cagaccgagg atgaggctga ttattactgc gcagcatggg atgataacct gagcggctac
      421 atcttcggtg ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCWK01005338             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:16787:3807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005338
VERSION     KCWK01005338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16787:3807"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..262
                     /note="immunoglobulin light chain variable region"
     V_region        7..262
     V_segment       7..225
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <187..>234
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71076.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       226..262
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        263..>300
                     /gene="IGLC"
BASE COUNT           65 a           92 c           78 g           65 t
ORIGIN      
        1 acatggggag acagcctcaa aacctattat gcaagctggt accagcagaa gccaggccag
       61 gtccctgtgc tggtcatcta tggtaacaac taccggccct cagggatccc aggccgattc
      121 tctgtctcct ggtcaggaaa cacaggttcc ttgaccatca ctgcggctca ggtggaagat
      181 gaggctgact attactgtaa gtcctgggac agcagtggta cccattacat cttcggtgct
      241 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005339             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:20032:9913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005339
VERSION     KCWK01005339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20032:9913"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..376
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71077.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       388..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          146 c          132 g           95 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctttgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaattaaa tttgtccact ggtaccagca gaagccagcg caggcccctg tgaaggtcat
      241 ctatgctgat gacaaacggc cctcagggat ccctgagaga ttctctggct ccaattcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattcctg
      361 tcaggtgtgg gacagtgaga ctgattatta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005340             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:23389:10491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005340
VERSION     KCWK01005340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:23389:10491"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..454
                     /note="immunoglobulin light chain variable region"
     V_region        124..454
     V_segment       124..417
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71078.1"
                     /translation="DYYCQSYDSTLIAVLF"
     J_segment       418..454
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           93 a          160 c          123 g          116 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact tcacagttcc agggtcctgg
      121 gcccagtctg tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc
      181 atctcctgca ctgggagcag ctccaacatt ggagattatt ttgtgcagtg gtaccagcac
      241 cttccaggaa cggcccccaa actcctcatc tatgaaaata ataagcgacc ctcaggcatt
      301 tctgatcgat tctctggctc ccagtctgga acctcagcct ccctgaccat cactggactc
      361 cagtctgagg atgaggctga ttattactgc cagtcctatg acagcacttt gattgctgtg
      421 ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCWK01005341             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:16466:10479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005341
VERSION     KCWK01005341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16466:10479"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..422
                     /note="immunoglobulin light chain variable region"
     V_region        99..422
     V_segment       99..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71079.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       387..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>461
                     /gene="IGLC"
BASE COUNT           91 a          146 c          127 g           97 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtcaaag tgtgcactgg taccagcaca agccaccgca ggcccctgtt ctggtcatct
      241 tttattatac cgaacggccc tcaggaatcc ctgagcgaat ctctggctcc aaatcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cacaagtctt gatcacggct tatttggagg agggacccgg ctgaccgtcc
      421 taagtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005342             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:13771:20369
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005342
VERSION     KCWK01005342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13771:20369"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71080.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          147 c          131 g           96 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gttctggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg aagctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaagt cttgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005343             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:7902:12084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005343
VERSION     KCWK01005343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:7902:12084"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..388
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71081.1"
                     /translation="DYYCDSWDSSGAQF"
     J_segment       389..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           90 a          141 c          127 g          100 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagagctct ggggtgtctc caccatggcc tggactcctc
       61 tctggctcac cctcctcagt ctttgcacag gttctatggt ttcttctgag ctgactcagg
      121 accctgcagt gtctgtggcc ttgggacaga cagtcaggat tacctgccaa ggagacagcc
      181 tcagaagctc ttatgcaaac tggtaccaac agaggccagg ccaggcccct gtgctggtcg
      241 tctatggtaa caactaccgg ccctcaggga tcccagagcg attctctggc tcctactcac
      301 gaaacacagc ttccttgacc atctctgggg ctcaggtgga agatgaggct gactattact
      361 gtgactcctg ggacagcagc ggagcccaat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005344             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:18114:8705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005344
VERSION     KCWK01005344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18114:8705"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..449
                     /note="immunoglobulin light chain variable region"
     V_region        116..449
     V_segment       116..412
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71082.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       413..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           84 a          168 c          129 g          106 t
ORIGIN      
        1 acatgggggc agtgtggctg cctcagcaga gccctgagga gtctgcacca tggcctggac
       61 cccaatcctc ctcctcctcc tcactctcct ccttcactgc acagggtctc tctcccagcc
      121 tgtgctgact cagtcgccct ctgcctctgc ctccctggga gcctcggtca agctcacctg
      181 cactctgagc agtggccact acagctacac catcgcatgg catcagcagc agcaagggaa
      241 ggcccctcgg ttcttgatgt ggcttaagag tgatggcagc cacaccaagg gggacggggt
      301 ccctgatcgc ttctcaggct ccagctccgg ggctgagcgc tacctcacca tctccaacct
      361 ccagtctgag gatgaggctg attattactg tcagacctgg gatattggca tttgggtatt
      421 cggcggaggg acccggctaa tcgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01005345             393 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:18935:7296
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005345
VERSION     KCWK01005345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 393)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18935:7296"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    22..355
                     /note="immunoglobulin light chain variable region"
     V_region        22..355
     V_segment       22..318
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <280..>327
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71083.1"
                     /translation="DYYCSSYAGSNTFVLF"
     J_segment       319..355
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        356..>393
                     /gene="IGLC"
BASE COUNT           73 a          126 c          101 g           93 t
ORIGIN      
        1 acatgggcag gatcctgggc tcagtctgcc ctgactcagc ctcgctcagt gtctgggtct
       61 cctggacagt cggtcaccat ctcctgcact ggaaccagca gtgacatcgg tggttataat
      121 tatgtctcct ggtaccaaca gtctccaggc acagccccca aactcgtgat ttttgaggtc
      181 aataaacggc cctcaggggt ctctgatcgc ttctctggct ccaagtctgg caacacggcc
      241 tccctgacca tctctgggct ccagcctgag gacgaggctg attattactg cagctcatat
      301 gcaggcagca acactttcgt gttgttcgga ggagggaccc ggctgaccgt cctaggtcag
      361 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005346             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:16178:5060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005346
VERSION     KCWK01005346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16178:5060"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..388
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71084.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       390..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          150 c          119 g          108 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac tcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accctctcct gcactgggag cagctccaac
      181 attggagatt attatgtgca gtggtaccag cagcttccag gaacggcccc caaactcctc
      241 atctatgaaa ataataagcg accctcaggg gtttctgatc gattctctgg ctcccagtct
      301 ggtacctcag cctccctgac catcactgga ctccagtctg acgatgaggc tgattattac
      361 tgtcagtcct atgatagcag cctgagtgtt gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005347             361 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:15524:13178
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005347
VERSION     KCWK01005347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 361)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15524:13178"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..323
                     /note="immunoglobulin light chain variable region"
     V_region        3..323
     V_segment       3..285
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <248..>295
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71085.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       287..323
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        324..>361
                     /gene="IGLC"
BASE COUNT           77 a          113 c          101 g           70 t
ORIGIN      
        1 acatgggctg actcagccac cctcggtgtc agtgtcccca ggacagacgg ccaggatcac
       61 ctgtggggga gacaacattg gaagtcaaag tgtgcactgg taccagcaca agccaccgca
      121 ggcccctgta ctggtcatct tttattatac cgaacggccc tcaggaatcc ctgagcgatt
      181 ctctggctcc aaatcaggga acaccgccac cctgaccatc agcggggtcg aggccgggga
      241 tgaggctgac tattactgtc aggtgtggga cacaactatt gatcacggct tcttcggagg
      301 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      361 g
//
LOCUS       KCWK01005348             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:7919:13574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005348
VERSION     KCWK01005348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7919:13574"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71086.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          163 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg acctggggtc cccaagcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005349             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:14876:20738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005349
VERSION     KCWK01005349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14876:20738"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..391
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71087.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       393..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          150 c          123 g          107 t
ORIGIN      
        1 acatgggggg cacaggaggc agcactcagg acagtctcca gcatggcctg gtctcctctc
       61 ctcctcaccc ttctcattca ctgcacaggg tcctgggccc agtctgtgct gacgcagccg
      121 ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct cctgcactgg gagcagctcc
      181 aacattggag gttattatgt gcagtggtac cagcagcttc caggaacggc ccccaaactc
      241 ctcatctatg aaaatgataa acgaccctca ggggtttctg atcgattctc tggctcccag
      301 tctgattcct cagcctccct gaccatcact ggactccagt ctgaggatga ggctgattat
      361 tactgccagt cctatgacag cagcttgagt gttgtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005350             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:5403:4162
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005350
VERSION     KCWK01005350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5403:4162"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71088.1"
                     /translation="DYYCQVWDSTSKWTF"
     J_segment       391..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          143 c          132 g           92 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgaac tgactcagtc
      121 accctcagtg tcagcggcct caggacagtc ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa actgtgcact ggtaccagca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgat agtaaacggc cgtcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtacta gtaaatggac attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005351             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:7319:9692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005351
VERSION     KCWK01005351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:7319:9692"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71089.1"
                     /translation="DYYCQVWDNSNKYTIF"
     J_segment       396..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          143 c          134 g           96 t
ORIGIN      
        1 acatggggct gactttggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactttacag gctctgcggc ctcctatgaa ttgactcagc
      121 cacgctcagt gtccgtgtcc ccgggacaga cggccaggat cacctgtggg ggagacaaga
      181 ttggaagtaa aagtgtacac tggtaccagc agaggccacc gcaggcccct gtattggtca
      241 tctatgttga tggcgaccgg ccctcaggga tccctgaacg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggataatagt aataaataca cgatcttcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005352             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:20594:16602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005352
VERSION     KCWK01005352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20594:16602"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..382
                     /note="immunoglobulin light chain variable region"
     V_region        58..382
     V_segment       58..344
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <307..>354
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71090.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       346..382
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>420
                     /gene="IGLC"
BASE COUNT           83 a          134 c          114 g           89 t
ORIGIN      
        1 acatggggga cttttctcct cctcggcctc cttgcttact gcacaggctc tgcggcctcc
       61 tatgatctga ctcagccacc ctcggtgtca gtgtccccag gacagacggc caggatcacc
      121 tgtgggggag acaacattgg aagtcaaagt gtgcactggt accagcacaa gccaccgcag
      181 gcccctgttc tggtcatctt ttattatacc gaacggccct caggaatccc tgagcgaatc
      241 tctggctcca aatcagggaa caccgccacc ctgaccatca gcggggtcga ggccggggat
      301 gaggctgact attactgtca ggtgtgggac acaagtcttg atcacggctt attcggagga
      361 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005353             297 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:14285:14409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005353
VERSION     KCWK01005353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 297)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14285:14409"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..259
                     /note="immunoglobulin light chain variable region"
     V_region        8..259
     V_segment       8..215
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <187..>231
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71091.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       229..259
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        260..>297
                     /gene="IGLC"
BASE COUNT           60 a           90 c           75 g           72 t
ORIGIN      
        1 acatggggtg atgttgggta ttatcatgct gtgtcttggt accagcatca tccaggcaaa
       61 gcccccaaac tcatgattta tgaggtcaat aaacggcccg caggggtctc tgatcgcttc
      121 tctggctcca agtctggcaa cacggcctcc ctgaccatct ctgggctcca gactgaggat
      181 gaggctgatt attactgcag ctcatatgca ggcagcaacg ctttattctt cggacgaggg
      241 acccgcctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005354             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:16689:6699
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005354
VERSION     KCWK01005354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16689:6699"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..226
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71092.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       231..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           62 a           94 c           77 g           68 t
ORIGIN      
        1 acatgggagc tccaatattg gaagtaattc tgtatactgg taccagcagt tcccaggaac
       61 ggcccccaaa ctcctcatct attatagtaa tcagcgaccc tcaggggtcc ctgaccgagt
      121 ctctggctct aagtcgggca cctcagcctc cctggccatc actggtctcc gatctgagga
      181 tgaggctgat tattactgtg cagcatggga tgacagcctg agaagtccgc tattcggcgg
      241 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01005355             281 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:19101:14688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005355
VERSION     KCWK01005355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 281)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19101:14688"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    11..243
                     /note="immunoglobulin light chain variable region"
     V_region        11..243
     V_segment       11..204
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <168..>215
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71093.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       211..243
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        244..>281
                     /gene="IGLC"
BASE COUNT           51 a           88 c           85 g           57 t
ORIGIN      
        1 acatgggagt tgtgaactgg taccagcaga agccagcgca ggcccctgta ttggtcatct
       61 ttgctgatac cgaacggccc gcagggatcc ccgagcgatt ctctggctcc aaatcaggga
      121 acacggccac cctgaccatc cgcggggtcg aggccgggga tgaggctgac ttttactgtc
      181 aggtgtggga cattcgtagt gatcgtccgc tattcggcgg agggacccgg ctcaccgtcc
      241 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005356             271 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:9261:15391
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005356
VERSION     KCWK01005356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 271)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 271)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..271
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9261:15391"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..233
                     /note="immunoglobulin light chain variable region"
     V_region        3..233
     V_segment       3..197
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <161..>205
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71094.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       201..233
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        234..>271
                     /gene="IGLC"
BASE COUNT           56 a           82 c           79 g           54 t
ORIGIN      
        1 acatgggcac tggtaccaac agaagccacc gcagggccct ctattggtca tctttgctga
       61 tagtagacgg ccctcaggga tccctgagcg attctctggc tccaactcag ggaacaccgc
      121 caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg
      181 ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc taggtcagcc
      241 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005357             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:26537:11842
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005357
VERSION     KCWK01005357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:26537:11842"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71095.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          162 c          124 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaaggaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005358             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:10578:17907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005358
VERSION     KCWK01005358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10578:17907"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71096.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           90 a          162 c          118 g          110 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggta ataaaaacat gtactggtac caacagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aactaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcaggtg tttgacagta gtgctgtgtt attcggagga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005359             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:25848:15249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005359
VERSION     KCWK01005359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:25848:15249"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71097.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           93 a          153 c          119 g          104 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtcaccatc tcctgttctg gaagcagctc
      181 caacatcgga agtaataatg tgtcctggta ccagcacctc ccaggaacag ctcccaaact
      241 cctcatctat tataatgatc aacgaggctc aggtgtctct gaccgattct ctggctccaa
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcgtgggatg atagcctgag cagttacatc ttcgctgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005360             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:12694:19466
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005360
VERSION     KCWK01005360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12694:19466"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71098.1"
                     /translation="DYHCQVWDLNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          141 c          136 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccagggtc acctgtgggg gagacaacat
      181 tgggagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat agcgagcggc cctcagggat ccctgaacga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actatcactg
      361 tcaggtgtgg gaccttaata gtcatcattt gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005361             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:23983:19498
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005361
VERSION     KCWK01005361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23983:19498"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..404
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71099.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          156 c          122 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcattgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagtagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005362             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:17012:3559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005362
VERSION     KCWK01005362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17012:3559"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..422
                     /note="immunoglobulin light chain variable region"
     V_region        92..422
     V_segment       92..385
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <347..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71100.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           88 a          155 c          116 g          101 t
ORIGIN      
        1 acatggggag gcagcactca ggacagtctc cagcatggcc tcgtctcctc tcctcctcac
       61 ccttctcatt cactgcacag ggtcctgggc ccagtctgtg ctgacacagc cgccctcagt
      121 gtctggggcc ccagggcaga gggtcaccat ctcctgcact gggagcagct ccaacattgg
      181 aggttattat atatcctggt accagcagct cccaggaacg gcccccaaac tcctcgtcta
      241 tgacaataat aagcgaccct caggggtttc tgaccgattc tctggctcca agtctggttc
      301 ctcagccacc ctgaccatca ctgggctcca gactgaggat gaggctgatt attactgcca
      361 gtcctatgac agcagtctga gtgctcgggt attcggcgga gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005363             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:6520:8848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005363
VERSION     KCWK01005363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:6520:8848"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    55..403
                     /note="immunoglobulin light chain variable region"
     V_region        55..403
     V_segment       55..366
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <331..>375
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71101.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       367..403
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        404..>441
                     /gene="IGLC"
BASE COUNT           84 a          153 c           96 g          108 t
ORIGIN      
        1 acatgggctc ctctcctcct cctgctcctc tctcactgca caggttccct ctcccagcct
       61 gtactgaccc agccaacctc cctctcagca tctccgggag catcagccag actcagctgc
      121 accttgagca gtggcatcaa tgttggtagt tacagcgtat tctggtacca gcagaagcca
      181 gggagtcctc cccggttcct tctgtactac tactcagact caagtaaaca ccagggctct
      241 ggagtcccca gccgcttctc tggatccaaa gatgcttcgg ccaatgcagg ccttttactg
      301 atctctaggc tccagtctga agatgaggct gactattact gtgccatatg gcacagcagc
      361 gcttcttact tcttcggtac tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc
      421 cccacggtca ctctgttccc g
//
LOCUS       KCWK01005364             366 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:24272:3658
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005364
VERSION     KCWK01005364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 366)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:24272:3658"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..328
                     /note="immunoglobulin light chain variable region"
     V_region        8..328
     V_segment       8..293
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <256..>300
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71102.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       298..328
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        329..>366
                     /gene="IGLC"
BASE COUNT           75 a          114 c           90 g           87 t
ORIGIN      
        1 acatgggcga ctcagactcc ctctgtgtcc gggtctcctg gacagtcggt caccatctcc
       61 tgcactggaa ccagcagtga tattgggtat tatcatgctg tgtcttggta ccaacatcat
      121 ccaggcaaag cccccaaact catgatttat gaggtcaata aacggcccgc aggggtctct
      181 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag
      241 actgaggatg aggctgatta ttactgcagc tcatatgcag gcagcaacac tttattcttc
      301 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      361 ttcccg
//
LOCUS       KCWK01005365             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:22144:9003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005365
VERSION     KCWK01005365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22144:9003"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..289
                     /note="immunoglobulin light chain variable region"
     V_region        8..289
     V_segment       8..252
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <214..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71103.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       253..289
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           69 a           99 c           79 g           80 t
ORIGIN      
        1 acatgggggg tcaccatctc ctgcactggg agcagctcca acattggaga ttattttgtg
       61 cagtggtacc agcaccttcc aggaacggcc cccaaactcc tcatctatga aaataataag
      121 cgaccctcag ggatttctga tcgattctct ggctcccagt ctggaacctc agcctccctg
      181 accatcactg gactccagtc tgaggatgag gctgattatt actgccagtc ctatgacagc
      241 agtttgattg ctgtgttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      301 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005366             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:25292:4840
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005366
VERSION     KCWK01005366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:25292:4840"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..425
                     /note="immunoglobulin light chain variable region"
     V_region        105..425
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71104.1"
                     /translation="DYFCQVWDSGSDHYIF"
     J_segment       392..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>467
                     /gene="IGLC"
BASE COUNT           86 a          149 c          133 g           99 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagttgactc
      121 agccaccctc ggtgtcagcg gcctctggac agacggccag gatcacctgt gggggagaca
      181 acattggaac tacatatgtg cactggtacc agcagaagcc accacaggcc cctgtgcagg
      241 tcatctttgc tgatagcaaa cggccctcag gggtccctga ccgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 tctgtcaggt gtgggacagt ggtagtgatc attacatctt cggtgttggg acccggctca
      421 ccgtcttagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01005367             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:11392:13822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005367
VERSION     KCWK01005367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11392:13822"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71105.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       401..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          152 c          117 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcttctcc tggagcatca gccagactca cctgcacctt gagcagtggc atcagtgttg
      181 gtacttacag gatattctgg taccagcaga ggccagggag tcctccccgg tatcttctga
      241 accaccacac agactcagat aaacatcagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcagggattt tgctcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtatg atttggcaca acaatgctta tgtgttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005368             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:7090:5841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005368
VERSION     KCWK01005368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7090:5841"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71106.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       400..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          156 c          128 g          101 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcgtctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttctgt tcacgcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgtaccc gcagcagagg
      181 caacattgac aatagttatg tgcagtggta ccagcagcgc ccgggcagtg ccccgaccac
      241 agtgatttac agagatgacc aaagagcctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctggg ctgaagtctg aggacgaggc
      361 tgactactac tgtcagtcta ctgatggcaa ctacaatcgg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005369             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:4326:6792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005369
VERSION     KCWK01005369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:4326:6792"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71107.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       392..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          145 c          136 g           96 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag actctgcggc ctcctatgat ctgacgcagc
      121 caccctcgat ttcagtgtcc ccaggacaga cggccaggct gacctgcggg ggagacaaca
      181 ttggaagtga agttgtgaac tggtaccagc agaagccacc gcaggcccct gtgttggtca
      241 tctatgctga cagcgagcgg ccctcaggga tccctgagcg attctctggc tccaagtcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggaccttaac agtcatcatc tcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005370             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:16103:7803
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005370
VERSION     KCWK01005370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16103:7803"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..268
                     /note="immunoglobulin light chain variable region"
     V_region        1..268
     V_segment       1..228
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>240
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71108.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       232..268
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        269..>306
                     /gene="IGLC"
BASE COUNT           65 a           83 c           91 g           67 t
ORIGIN      
        1 acatgggggg gagacaatat tggaagtgaa gttgtcaact ggtaccagca gaagccaccg
       61 caggcccctg tggtggtcat ctatgctgat tatgaacggc cctcagggat ccctgagcga
      121 ttctctggct ccaaatcagg gaacacggcc accctgacca tcagcggagt cgaggccggg
      181 gatgaggctg actattactg tcaggtttgg gacatttata ttgatcatcc ggtgttattc
      241 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      301 ttcccg
//
LOCUS       KCWK01005371             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:23122:18834
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005371
VERSION     KCWK01005371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:23122:18834"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71109.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          164 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tatctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005372             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:22820:17561
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005372
VERSION     KCWK01005372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:22820:17561"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    69..392
                     /note="immunoglobulin light chain variable region"
     V_region        69..392
     V_segment       69..356
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <318..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71110.1"
                     /translation="DYYCQVWDSSTKYAVF"
     J_segment       359..392
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>431
                     /gene="IGLC"
BASE COUNT           94 a          138 c          115 g           84 t
ORIGIN      
        1 acatgggagc catggcctgg acccttctcc tcctcggcct cctcgcttac tgcacagact
       61 ctacgacttc ctatgagctg actcagccac cctcagtgtc agcggccgca gggcagacgg
      121 ccaggatcac ctgtgagaca gacaacattg gaagaaaaag tgtccactgg taccaccaga
      181 agccaccgca ggcccctgtg gtggtcatct atgatgataa cagtcggccc tcagggatcc
      241 ctgagcgatt ctctggctcc aattcaggga acaccgccac cctgaccatc aatagggtcg
      301 aggccgggga tgaggctgac tattactgtc aggtgtggga cagtagtact aaatacgcgg
      361 tattcggcgg agggacccgg ctaaccgtcc tacgtcagcc caaggctgcc ccctcggtca
      421 ctctcttccc g
//
LOCUS       KCWK01005373             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:6276:17288
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005373
VERSION     KCWK01005373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6276:17288"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71111.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          161 c          112 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctttg
      301 gatccaaaga tgcttcagcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggccga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005374             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:12031:20087
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005374
VERSION     KCWK01005374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12031:20087"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..409
                     /note="immunoglobulin light chain variable region"
     V_region        79..409
     V_segment       79..372
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <334..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71112.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       374..409
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           84 a          151 c          112 g          100 t
ORIGIN      
        1 acatggggga cagtctccag catggcctcg tctcctctcc tcctcaccct tctcattcac
       61 tgcacagggt cctgggccca gtctgtgctg acacagccgc cctcagtgtc tggggcccca
      121 gggcagaggg tcaccatctc ctgcactggg agcagctcca acattggagg ttattatata
      181 tcctggtacc agcagctccc aggaacggcc cccaaactcc tcgtctatga caataataag
      241 cgaccctcag gggtttctga ccgattctct ggctccaagt ctggttcctc agccaccctg
      301 accatcactg ggctccagac tgaggatgag gctgattatt actgccagtc ctatgacagc
      361 agtctgagtg ctcgggtatt cggcggaggg acccggctaa ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005375             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:14709:6769
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005375
VERSION     KCWK01005375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14709:6769"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71113.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           91 a          146 c          127 g           97 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtcaaag tgtgcactgg taccagcaca agccaccgca ggcccctgta ctggtcatct
      241 tttattatac cgaacggccc tcaggaatcc ctgagcgatt ctctggctcc aaatcaggga
      301 ataccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cacaactatt gatcacggct tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005376             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:8036:3776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005376
VERSION     KCWK01005376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8036:3776"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..435
                     /note="immunoglobulin light chain variable region"
     V_region        115..435
     V_segment       115..399
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71114.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       400..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>474
                     /gene="IGLC"
BASE COUNT           98 a          145 c          130 g          101 t
ORIGIN      
        1 acatggggca gagtacatgg gggtgggctc aggaggcaga gctctgggtg tctcaccatg
       61 gcctggattc ctctcctact ccccatcctc actttctgca caggctctgc agcctcctat
      121 gagctgacac agccaccctc ggtgtcagtg tccccaggac agacggccaa gatcacctgc
      181 tctggagatg cactgccaaa aaaatatgct tattggttcc agcagaagcc aggccagtcc
      241 cctgtgttga tcatcgatga ggacaccaaa cggccctctg ggatccctga gagattctct
      301 ggctccagct cagggacagt ggccaccttg actatcagtg gggcccaggt ggaggatgaa
      361 gctgactact actgttactc agcagacagc agtggttatg gcttattcgg aggagggacc
      421 cggctgaccg tcctacgtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005377             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:15527:9069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005377
VERSION     KCWK01005377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15527:9069"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..260
                     /note="immunoglobulin light chain variable region"
     V_region        5..260
     V_segment       5..222
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <185..>232
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71115.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       224..260
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>298
                     /gene="IGLC"
BASE COUNT           66 a           90 c           81 g           61 t
ORIGIN      
        1 acatggggac aacattggaa gtcaaagtgt gcactggtac cagcacaagc caccgcaggc
       61 ccctgtactg gtcatctttt attataccga acggccctca ggaatccctg agcgattctc
      121 tggctccaaa tcagggaata ccgccaccct gaccatcagc ggggtcgagg ccggggatga
      181 ggctgactat tactgtcagg tgtgggacac aactattgat cacggcttat tcggaggagg
      241 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005378             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:10002:12602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005378
VERSION     KCWK01005378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10002:12602"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71116.1"
                     /translation="DYYCHVYDTTTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          167 c          118 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atttactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgcg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcctctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacac tactactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005379             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:16060:14839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005379
VERSION     KCWK01005379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16060:14839"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..398
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71117.1"
                     /translation="DYYCSSYGGSNSLFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           89 a          151 c          121 g          110 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 actccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgatattg ggtattatca tgctgtgtct tggtaccagc atcatccagg caaagccccc
      241 aaactcatga tttatgaggt caataaacgg cccgcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 gattattact gcagctcata tggaggcagc aatagtttat tcttcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005380             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:13680:9970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005380
VERSION     KCWK01005380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13680:9970"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..409
                     /note="immunoglobulin light chain variable region"
     V_region        88..409
     V_segment       88..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71118.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       373..409
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           87 a          141 c          119 g          100 t
ORIGIN      
        1 acatgggggc agagctctgg gtgtctcacc atggcctgga ttcctctcct actccccatc
       61 ctcactttct gcacaggctc tgcagcctcc tatgagctga cacagccacc ctcggtgtca
      121 gtgtccccag gacagccggc caggatcacc tgctctggag atgtattgcc aaaaaaatat
      181 gcttattggt tccagcagaa gccaggccag tcccctgtat tggtcatctc tgaggacacc
      241 gaacggccct ctgggatccc tgagagattc tctggctcca gctcagggac agtggccacc
      301 ttgactatca gtggggccca ggtggaggat gaagctgact actactgtta ctcagcagac
      361 agtagtggtc atggcttctt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005381             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13156:10696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005381
VERSION     KCWK01005381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13156:10696"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71119.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          157 c          123 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctactataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagac tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005382             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:12284:16238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005382
VERSION     KCWK01005382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12284:16238"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..250
                     /note="immunoglobulin light chain variable region"
     V_region        7..250
     V_segment       7..213
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <175..>222
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71120.1"
                     /translation="DYFCAAWDDSLTGYIF"
     J_segment       214..250
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        251..>288
                     /gene="IGLC"
BASE COUNT           56 a           90 c           74 g           68 t
ORIGIN      
        1 acatggggaa gtaatagtgt gtcctggtac cagcagctcc cagaaacggc tcccaaactc
       61 ctcatctatt atgatcatcg gcgagcctca ggtgtctctg accgattctc tggctccaag
      121 tctggcacgt cagcctccct ggccatcagt ggactccaga ccgaggatga ggctgattat
      181 ttctgcgcag catgggatga tagcctgacc ggttacattt tcggtgctgg gacccggctc
      241 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01005383             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:10318:17577
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005383
VERSION     KCWK01005383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10318:17577"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71121.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       398..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          164 c          124 g          102 t
ORIGIN      
        1 acatggggga gcagagccct gaggagtctg caccatggcc tggaccccaa tcctcctcct
       61 cctcctcact ctcctccttc actgcacagg gtctctctcc cagcctgtgc tgactcagtc
      121 gccctctgcc tctgcctccc tgggagcctc ggtcaagctc acctgcactc tgagcagtgg
      181 ccactacagc tacaccatcg catggcatca gcagcagcaa gggaaggccc ctcggttctt
      241 gatgtggctt aagagtgatg gcagccacac caagggggac ggggtccctg atcgcttctc
      301 aggctccagc tccggggctg agcgctacct caccatctcc aacctccagt ctgaggatga
      361 ggctgattat tactgtcaga cctgggatat tggcatttgg gttttcggcg gagggacccg
      421 gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005384             277 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:20023:5421
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005384
VERSION     KCWK01005384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 277)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20023:5421"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..239
                     /note="immunoglobulin light chain variable region"
     V_region        8..239
     V_segment       8..202
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <164..>211
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71122.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       203..239
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        240..>277
                     /gene="IGLC"
BASE COUNT           55 a           89 c           75 g           58 t
ORIGIN      
        1 acatggggtg cactggtacc agcacaagcc accgcaggcc cctatcctgg tcatctatta
       61 ttataccgaa cggccctcgg cgatccctga gcgattctct ggctccaaat cagggaacac
      121 cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt actgtcaggt
      181 gtgggacact actattgatc atggcttttt cggaggaggg acccggctca ccgtcctagg
      241 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01005385             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:19385:10779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005385
VERSION     KCWK01005385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19385:10779"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..423
                     /note="immunoglobulin light chain variable region"
     V_region        93..423
     V_segment       93..384
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71123.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       389..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           87 a          147 c          119 g          108 t
ORIGIN      
        1 acatggggga ggcagcactc aggacagtct ccagcatggc ctggtctcct ctcctcctca
       61 cccttctcat tcactgcaca gggtcctggg cccagtctgt gctgacgcag ccgccctcag
      121 tgtctggggc gcccgggcag agggtcacga tctcctgcag tgggagcaac tccaacattg
      181 gatattatta tgtgcagtgg taccagcagc ttccaggaac ggcccccaaa ctcctcatct
      241 atgaaaataa taagcgaccc tctggggttt ctgatcgatt ctctggctcc cagtctggta
      301 cctcagcctc cctgaccatc actggactcc agtctgagga tgaggctgat tattactgcc
      361 actcctatga cagcagtttg agtggtgtct tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005386             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:4347:7864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005386
VERSION     KCWK01005386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:4347:7864"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71124.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       415..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           93 a          161 c          126 g          108 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctc gtctcctctc ctcctcaccc ttttcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacacagccg ccctcagtgt ctggggcccc agggcagagg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag gttattatat atcctggtac cagcagctcc
      241 caggaacggc ccccaaactc ctcgtctatg acaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggttcct cagccaccct gaccatcact gggctccaga
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagtctgagt gctcgggtat
      421 tcggcggagg gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01005387             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:17721:9570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005387
VERSION     KCWK01005387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17721:9570"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..398
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71125.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           89 a          154 c          119 g          109 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 actccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgatattg ggtattatca tgctgtgtct tggtaccagc atcatccagg caaagccccc
      241 aaactcatga tttatgaggt caataaacgg cccgcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 gattattact gcagctcata tgcaggcagc aacactttat tcttcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005388             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:20553:14806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005388
VERSION     KCWK01005388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20553:14806"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..440
                     /note="immunoglobulin light chain variable region"
     V_region        92..440
     V_segment       92..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71126.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       403..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           96 a          156 c          118 g          108 t
ORIGIN      
        1 acatgggact gtggggaaag aggctgtgtc caccatggcc tggactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc caagcctatg ctgactcagc cggcctccct
      121 ctcagcatct cctggagcat cagccagtct cacatgcacc ttcagcggtg gcatcaatgt
      181 tgctggctac cacatacact ggtaccagca gaagccaggg agtcctcccc gatatcttct
      241 gagatacaaa tcggactcag ataagggcca gggctctgga gtccccagcc gcttctctgg
      301 atccaaagat gcttcaggga acacagggat tttacgcatc tctggactcc agtctgagga
      361 tgaggctgac tattactgtg ccatcggaca cagcagcggt gattacatct tcggtgctgg
      421 gacccggctc agcgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01005389             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:3756:14984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005389
VERSION     KCWK01005389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:3756:14984"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..436
                     /note="immunoglobulin light chain variable region"
     V_region        90..436
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71127.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           91 a          162 c          110 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt tagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc ggtactggga
      421 cccggctcac cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005390             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10343:6603
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005390
VERSION     KCWK01005390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10343:6603"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71128.1"
                     /translation="DYYCAAWDDTLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          156 c          127 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagcg ggtccaatat cggaagtaat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca agctcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagcgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataccc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005391             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:15905:11047
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005391
VERSION     KCWK01005391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15905:11047"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71129.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       394..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          156 c          119 g          102 t
ORIGIN      
        1 acatgggggc acaggaggca gcactcagga cagtctccag catggcctcg tctcctctcc
       61 tcctcaccct tttcattcac tgcacagggt cctgggccca gtctgtgctg acacagccgc
      121 cctcagtgtc tggggcccca gggcagaggg tcaccatctc ctgcactggg agcagctcca
      181 acattggagg ttattatata tcctggtacc agcagctccc aggaacggcc cccaaactcc
      241 tcgtctatga caataataag cgaccctcag gggtttctga ccgattctct ggctccaagt
      301 ctggttcctc agccaccctg accatcactg ggctccagac tgaggatgag gctgattatt
      361 actgccagtc ctatgacagc agtctgagtg ctcgggtatt cggcggaggg acccggctaa
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005392             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:20950:8802
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005392
VERSION     KCWK01005392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20950:8802"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71130.1"
                     /translation="DYYCAAWDESLRGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           96 a          156 c          127 g          103 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgcgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctgggagcag ctccaacatc ggaagaaata gtgtatcctg gtaccagcag ctcccaggaa
      241 cagctcccaa aatcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagccg ccctggccat cagcgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgaaagcct gaggggttac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01005393             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18236:13936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005393
VERSION     KCWK01005393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18236:13936"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71131.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          136 c          122 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggtccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005394             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:28861:9953
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005394
VERSION     KCWK01005394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:28861:9953"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..251
                     /note="immunoglobulin light chain variable region"
     V_region        7..251
     V_segment       7..208
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <173..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71132.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       214..251
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           65 a           89 c           62 g           73 t
ORIGIN      
        1 acatgggggt tattatgtat cctggtacca gcagttccca ggaacagccc ccaaactcct
       61 catctatgaa aataataaac gaccctcagg ggtttctgac cgattctctg gctccaagtc
      121 tggtacctca gcctccctga ccatcactgg actccaatct gaggatgagg ctgattatta
      181 ctgctcagca tgggatagca gcctgagtat caattacatc ttcggttctg ggacccgtct
      241 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005395             450 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:13993:20903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005395
VERSION     KCWK01005395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13993:20903"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..412
                     /note="immunoglobulin light chain variable region"
     V_region        88..412
     V_segment       88..363
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71133.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       375..412
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>450
                     /gene="IGLC"
BASE COUNT           89 a          142 c          124 g           95 t
ORIGIN      
        1 acatggggca gcattgacgg tgcctcagcc atggcctgga cccttctcct cctcggcctc
       61 ctcgctcact gcacaggctc tgcgacctcc tttgagttga ctcagccacc ctcggtgtca
      121 gcggcctcag gacagacggc caggatcacc tgtgggggag acaacattgg aattaaattt
      181 gtccactggt accagcagaa gccagcgcag gcccctgtga aggtcatcta tgctgatgac
      241 aaacggccct cagggatccc tgagagattc tctggctcca attcagggaa caccgccacc
      301 ctgaccatca gcggggtcga ggccggggat gaggctgatt attcctgtca ggtgtgggac
      361 agtgagactg attattacat cttcggtact gggacccggc tcaccgtcct aggtcagccc
      421 aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005396             432 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:15165:4562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005396
VERSION     KCWK01005396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 432)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15165:4562"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    70..394
                     /note="immunoglobulin light chain variable region"
     V_region        70..394
     V_segment       70..351
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <319..>366
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71134.1"
                     /translation="DYYCQVWDSSSDHWIF"
     J_segment       357..394
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        395..>432
                     /gene="IGLC"
BASE COUNT           87 a          139 c          123 g           83 t
ORIGIN      
        1 acatggggag ccatggcctg gacccttctc ctcctcggcc tcctcgctca ctgcacagac
       61 tctgcgacct cctatgagct gactcagcca ccctcggtgt cagcggcctc aggacagacg
      121 gccaggatca cctgtggggg agacaacatt ggaagtaaat atgtgcactg gtaccagcag
      181 aggccaccgc aggcccctgt gcaagtcatc tatactgata gcagacggcc ctcagggatc
      241 cctgagcgat tctctggctc caactcaggg aacaccgcca ccctgaccat cagcgcggtc
      301 gaggccgggg atgaggctga ctattactgt caggtgtggg acagtagtag tgatcattgg
      361 atattcggcg gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      421 actctcttcc cg
//
LOCUS       KCWK01005397             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:17250:12770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005397
VERSION     KCWK01005397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17250:12770"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..446
                     /note="immunoglobulin light chain variable region"
     V_region        101..446
     V_segment       101..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71135.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           90 a          162 c          122 g          110 t
ORIGIN      
        1 acatgggggg gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagcagtga
      181 cctcagtgtt ggtaataaaa acatgtactg gtaccaacag aagccaggga gcgctcccag
      241 gttattcctg tactactact ccgactcaga caagcagctg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaactaa cacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt attactgtca ggtgtttgac agtagtgctg tgttattcgg
      421 aggagggacc cgactgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01005398             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:25664:10993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005398
VERSION     KCWK01005398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25664:10993"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71136.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           96 a          155 c          116 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggaacatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catatactgg taccaccaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacacatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacaca gcagcggtga ttatatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005399             391 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:12575:12504
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005399
VERSION     KCWK01005399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 391)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12575:12504"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..353
                     /note="immunoglobulin light chain variable region"
     V_region        23..353
     V_segment       23..316
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <278..>325
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71137.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       318..353
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        354..>391
                     /gene="IGLC"
BASE COUNT           76 a          126 c          105 g           84 t
ORIGIN      
        1 acatggggca gggtcctggg cccagtctgt gctgacacag ccgccctcag tgtctggggc
       61 cccagggcag agggtcacca tctcctgcac tgggagcagc tccaacattg gaggttatta
      121 tatatcctgg taccagcagc tcccaggaac ggcccccaaa ctcctcgtct atgacaataa
      181 taagcgaccc tcaggggttt ctgaccgatt ctctggctcc aagtctggtt cctcagccac
      241 cctgaccatc actgggctcc agactgagga tgaggctgat tattactgcc agtcctatga
      301 cagcagtctg agtgctcggg tattcggcgg agggacccgg ctaaccgtcc taggtcagcc
      361 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005400             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:10319:3826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005400
VERSION     KCWK01005400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10319:3826"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71138.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          148 c          132 g           95 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctttga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaatta aatttgtcca ctggtaccag cagaagccag cgcaggcccc tgtgaaggtc
      241 atctatgctg atgacaaacg gccctcaggg atccctgaga gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattcc
      361 tgtcaggtgt gggacagtga gactgatcat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005401             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:8019:19503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005401
VERSION     KCWK01005401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8019:19503"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71139.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           84 a          149 c          138 g           93 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag actctgcggc ctcccatgat ctgactcagc
      121 caccctcggt gaccgtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttcgaagtga agttgtgaac tggtaccagc agaagccagc gcaggcccct gtattggtca
      241 tctttgctga taccgaacgg cccgcaggga tccccgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atccgcgggg tcgaggccgg ggatgaggct gacttttact
      361 gtcaggtgtg ggacattcgt agtgatcgtc cgctattcgg cggagggacc cggctcaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005402             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22860:11621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005402
VERSION     KCWK01005402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22860:11621"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..263
                     /note="immunoglobulin light chain variable region"
     V_region        4..263
     V_segment       4..226
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71140.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       229..263
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           60 a           94 c           78 g           69 t
ORIGIN      
        1 acatgggagt tacagcgtat tctggtacca gcagaagcca gggagtcctc cccggtacct
       61 tctgtactac cagtcagact caaggaaaca ccagggctct ggagtcccca gccgcttctc
      121 tggatccaaa gatgcttcag ccaatgcagg gctgttactg atctctgggc tccagtctga
      181 agatgaggct gactattact gtgccctatg gcacagcagc gcttcttgca tcttcggtgg
      241 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      301 g
//
LOCUS       KCWK01005403             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:25338:13497
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005403
VERSION     KCWK01005403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:25338:13497"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71141.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          156 c          119 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggaaca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgttggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcggactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacgcaggga ttttacgcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005404             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:24520:7956
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005404
VERSION     KCWK01005404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24520:7956"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71142.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          148 c          130 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctccgatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtga gggagacaac
      181 attggaagta agagtgtgca ctggtaccag cacaagccac cgcaggcccc tatcctggtc
      241 atctattatt ataccgaacg gccctcggcg atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacactac tattgatcat ggctttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005405             354 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:11631:5512
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005405
VERSION     KCWK01005405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 354)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:11631:5512"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..316
                     /note="immunoglobulin light chain variable region"
     V_region        8..316
     V_segment       8..278
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <241..>288
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71143.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       280..316
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        317..>354
                     /gene="IGLC"
BASE COUNT           77 a          109 c          100 g           68 t
ORIGIN      
        1 acatgggagc caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg
       61 ggagacaaca ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct
      121 gtactggtca tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc
      181 tccaaatcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct
      241 gactattact gtcaggtgtg ggacacaact attgatcacg gcttattcgg aggagggacc
      301 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005406             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:17259:16914
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005406
VERSION     KCWK01005406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17259:16914"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71144.1"
                     /translation="DYYCASYEGSNTFLF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          158 c          120 g          105 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca gtggaaccag
      181 cactaagatt gggtatcaca atgctgtgtc ctggtaccaa gagcatccag gcaaagcccc
      241 caaactcatg atttatgacg tcaataagcg gcccacaggg atctctgatc gcttctctgg
      301 ctccaagtct ggcgacacgg cctccctgac catctctggg ctccaggctg atgatgaggc
      361 tgattattac tgcgcctcat atgaaggcag caatactttc ctcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005407             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:23796:7239
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005407
VERSION     KCWK01005407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23796:7239"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71145.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           83 a          163 c          123 g          102 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggc
      181 cactacagct acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggttcttg
      241 atgtggctta agagtgatgg cagccacacc aagggggacg gggtccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatatt ggcatttggg tattcggcgg agggacccgg
      421 ctaatcgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005408             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:15853:8213
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005408
VERSION     KCWK01005408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15853:8213"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71146.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          160 c          125 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct cccagtctgg cacgtcggcc tccctggcca tcagtggcct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005409             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:18094:4155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005409
VERSION     KCWK01005409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:18094:4155"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71147.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       392..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          149 c          138 g           91 t
ORIGIN      
        1 acatgggctg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag ggactgcgac ctcctatgag ctggctcagc
      121 caccctcggt gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa ctatgtgcac tggtaccagc agaagccagc gcaggcccct gtagaggtca
      241 tctttgctga taacaaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggatcaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactatttct
      361 gtcaggtgtg gggcagtcgt agtgatcatc cggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005410             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:17417:7266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005410
VERSION     KCWK01005410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17417:7266"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..397
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71148.1"
                     /translation="DYYCSSYGGSNTLFF"
     J_segment       402..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           90 a          152 c          119 g          109 t
ORIGIN      
        1 acatggggga tctcaggagg cagcgctctc aggacttctc caccatggtc tgggctctgc
       61 tcctcctcac cctcctcact cagggcacag gatcctgggc tcaggctgcc ccgactcaga
      121 ctccctctgt gtccgggtct cctggacagt cggtcaccat cacctgcact ggaaccagca
      181 gtgatattgg gtattatcat gctgtgtctt ggtaccagca tcatccaggc aaagccccca
      241 aactcatgat ttatgaggtc aataaacggc ccgcaggggt ctctgatcgc ttctctggct
      301 ccaagtctgg caacacggcc tccctgacca tctctgggct ccagactgag gatgaggctg
      361 attattactg cagctcatat ggaggcagca atactttatt cttcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005411             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:15176:13291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005411
VERSION     KCWK01005411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15176:13291"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..431
                     /note="immunoglobulin light chain variable region"
     V_region        90..431
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71149.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>473
                     /gene="IGLC"
BASE COUNT           92 a          159 c          111 g          111 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt gctgggaccc
      421 ggctcaccgt cttaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005412             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:14688:8512
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005412
VERSION     KCWK01005412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14688:8512"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71150.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           82 a          156 c          128 g          107 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcagcgct ctcgggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcagtct gccctgactc
      121 agcctccctc agtgtccaag tctcttggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat tggtggttat gatggcgtct cctggtacca gcagcactca gggacagccc
      241 ccagactcct gatttatgat gtcactaagc ggccctcagg ggtctcggat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctca ccatctctgg gctccagact gaggacgagg
      361 ctgattatta ttgttgctca tataggagtg gaaacacttg gctattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005413             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:12348:8315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005413
VERSION     KCWK01005413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12348:8315"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..456
                     /note="immunoglobulin light chain variable region"
     V_region        126..456
     V_segment       126..419
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71151.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       420..456
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           95 a          158 c          125 g          116 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca cttcacagtt ccagggtcct
      121 gggcccagtc tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca
      181 ccatctcctg cactgggagc agctccaaca ttggagatta ttttgtgcag tggtaccagc
      241 accttccagg aacggccccc aaactcctca tctatgaaaa taataagcga ccctcaggaa
      301 tttctgatcg attctctggc tcccagtctg gaacctcagc ctccctgacc atcactggac
      361 tccagtctga ggatgaggct gattattact gccagtccta tgacagcagt ttgattgctg
      421 tgttattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      481 tcactctctt cccg
//
LOCUS       KCWK01005414             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:15489:2995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005414
VERSION     KCWK01005414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15489:2995"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71152.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>479
                     /gene="IGLC"
BASE COUNT           94 a          158 c          118 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaaaccttt gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccatatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcagactca gatcagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacata ttcggtgccg
      421 ggacccggct caccgtccca ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005415             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:25092:18276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005415
VERSION     KCWK01005415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:25092:18276"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71153.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          163 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca aacagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tatttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005416             328 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:18232:13384
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005416
VERSION     KCWK01005416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 328)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18232:13384"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..290
                     /note="immunoglobulin light chain variable region"
     V_region        8..290
     V_segment       8..253
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>262
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71154.1"
                     /translation="DYFCQVWDSISDHPLF"
     J_segment       256..290
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        291..>328
                     /gene="IGLC"
BASE COUNT           71 a           95 c           98 g           64 t
ORIGIN      
        1 acatggggga cagacggcca ggatcacctg tgggggagac aacattggaa ctaaatatgt
       61 gcactggtac cagcagaagc cagcgcaggc ccctgtgcag gtcatttatg gtgataccaa
      121 acggccctca gggatccctg agcgattctc tggctccaac tcagggaaca ccgccaccct
      181 gaccatcagc ggggtcgagg ccggggatga ggctgactat ttctgtcagg tgtgggacag
      241 tattagtgat catcccttat tcggaggagg gacccggctg accgtcctag gtcagcccaa
      301 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005417             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:20314:11215
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005417
VERSION     KCWK01005417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20314:11215"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71155.1"
                     /translation="DYYCQVYDSGANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          164 c          124 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagcgttgg tagtaaaaat atgtactggt accagcagaa gccagggagc gctcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacgt ggccgactat tactgtcagg tgtatgacag tggtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005418             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:16491:11475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005418
VERSION     KCWK01005418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16491:11475"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..397
                     /note="immunoglobulin light chain variable region"
     V_region        76..397
     V_segment       76..360
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>369
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71156.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       361..397
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        398..>435
                     /gene="IGLC"
BASE COUNT           86 a          138 c          113 g           98 t
ORIGIN      
        1 acatgggggt gtctcaccat ggcctggatt cctctcctac tccccatcct cactttctgc
       61 acaggctctg cagcctccta tgagctgaca cagccaccct cggtgtcagt gtccccagga
      121 cagccggcca ggatcacctg ctctggagat gtattgccaa aaaaatatgc ttattggttc
      181 cagcagaagc caggccagtc ccctgtattg gtcatctctg aggacaccaa acggccctct
      241 gggatccctg agagattctc tggctccagc tcagggacag tggccacctt gactatcagt
      301 ggggcccagg tggaggatga agctgactac tactgttact cagcagacag tagtggtcat
      361 ggcttcttcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      421 gtcactctct tcccg
//
LOCUS       KCWK01005419             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:14920:24453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005419
VERSION     KCWK01005419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14920:24453"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71157.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          154 c          120 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca gtggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcgtccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctggtc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaagc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcggac gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005420             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:14142:4269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005420
VERSION     KCWK01005420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14142:4269"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71158.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          105 a          137 c          122 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtctgtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca acagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccgagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005421             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:19347:19307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005421
VERSION     KCWK01005421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19347:19307"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71159.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          142 c          133 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca gggtctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacctg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005422             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:19325:8729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005422
VERSION     KCWK01005422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19325:8729"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71160.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           89 a          152 c          121 g          111 t
ORIGIN      
        1 acatgggggt ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgtagctca tatgcaggca gcaacagttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005423             248 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:23790:4606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005423
VERSION     KCWK01005423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 248)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 248)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..248
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:23790:4606"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..210
                     /note="immunoglobulin light chain variable region"
     V_region        1..210
     V_segment       1..171
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <135..>182
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71161.1"
                     /translation="DYYCQSYDSSLSGVLF"
     J_segment       176..210
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        211..>248
                     /gene="IGLC"
BASE COUNT           48 a           77 c           61 g           62 t
ORIGIN      
        1 atgggacggc ccccaaactc ctcatctatg aaaataataa gcgaccctct ggggtttctg
       61 atcgattctc tggctcccag tctggtacct cagcctccct gaccatcact ggactccagt
      121 ctgaggatga ggctgattat tactgccagt cctatgacag cagtttgagt ggtgtcttat
      181 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      241 tcttcccg
//
LOCUS       KCWK01005424             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:28130:12979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005424
VERSION     KCWK01005424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:28130:12979"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71162.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttgttcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005425             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:26341:6891
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005425
VERSION     KCWK01005425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:26341:6891"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..391
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71163.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          145 c          134 g           94 t
ORIGIN      
        1 acatgggggg tctgggtctc aggaggcagc attgacggtg cctcagccat ggcctggacc
       61 cttctcctcc tcggcctcct cgcttactgc acaggctctt cgacctccta tgaactgact
      121 cagtcaccct cagtgtcagc ggcctcagga cagccggcca ggatcacctg tgggggagac
      181 aacattggaa ctaaaactgt gcactggtac cagcagaagc caccgcaggg ccctgtattg
      241 gtcatctttg ctgacagtaa acggccctca gggatccctg agcgattctc tggctccaac
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtagtaaa tggatattcg gcggggggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005426             345 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:9862:7050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005426
VERSION     KCWK01005426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 345)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:9862:7050"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..307
                     /note="immunoglobulin light chain variable region"
     V_region        8..307
     V_segment       8..270
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <235..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71164.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       271..307
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>345
                     /gene="IGLC"
BASE COUNT           77 a          108 c           82 g           78 t
ORIGIN      
        1 acatgggcag ccagtctcac atgcaccttc agcggtggca tcaatgttgt tgcctaccac
       61 atacactggt accagcagaa gccagggagt cccccccggt atcttctgag ttacaaatca
      121 gactcagata agggccaggg ctctggagtc cccagccgct tctctggatc caaaaatggt
      181 tcaacaaaca caggcatttt acacatctct gggctccagt ctgaggatga ggctgactat
      241 ttctgtgcca ttggacacag cagcggtcct tacatcttcg gtactgggac ccggctcacc
      301 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005427             352 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:19634:16112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005427
VERSION     KCWK01005427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 352)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 352)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19634:16112"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..314
                     /note="immunoglobulin light chain variable region"
     V_region        8..314
     V_segment       8..274
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <242..>286
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71165.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       277..314
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        315..>352
                     /gene="IGLC"
BASE COUNT           74 a          113 c           89 g           76 t
ORIGIN      
        1 acatggggga gcatcagccc gtctcacatg caccttcagc ggtggcatca ctgttgctgc
       61 ctaccacata cactggtacc aacagaagcc acggagtcct ccccggtatc ttctgaggtt
      121 caaatcagac tcagataagg accagggctc tggagtcccc agccgcttct ctggatccaa
      181 agatgcctca gcgaacacag ggattttacg catctctggg ctccagtctg aggatgaggc
      241 tgactactac tgtgccattg ggcacagcag cggtgattac atcttcggtg ctgggacccg
      301 cctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01005428             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:12553:8354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005428
VERSION     KCWK01005428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12553:8354"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71166.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          157 c          125 g          100 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcat cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtggacac
      181 aggagctaca ccatcgcgtg gcatcagcag cagcaaggga aggcccctcg atacttgatg
      241 tggcttaaaa gtgatggcag ccacagcaag ggggacggga tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattatt gtcagacgtg ggatattggc atttgggtgt tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005429             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:7257:15089
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005429
VERSION     KCWK01005429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7257:15089"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..449
                     /note="immunoglobulin light chain variable region"
     V_region        101..449
     V_segment       101..412
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71167.1"
                     /translation="DYYCHVYDSSANVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           88 a          161 c          124 g          114 t
ORIGIN      
        1 acatggggct gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcactc tgagcagtga
      181 cctcagtgtt ggtggtaaaa gcatgtactg gtaccagcag aagccaggga gcgctcccag
      241 gttattcctg ttctactact ccgactcagg caagcagttg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt attactgtca cgtatatgac agtagtgcta atgtgttatt
      421 cggaggaggg acccgactga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01005430             349 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:23346:21284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005430
VERSION     KCWK01005430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 349)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23346:21284"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..311
                     /note="immunoglobulin light chain variable region"
     V_region        8..311
     V_segment       8..273
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <236..>283
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71168.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       275..311
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        312..>349
                     /gene="IGLC"
BASE COUNT           75 a          107 c           99 g           68 t
ORIGIN      
        1 acatgggccc tcggtgtcag tgtccccagg acagacggcc aggatcacct gtgggggaga
       61 caacattgga agtcaaagtg tgcactggta ccagcacaag ccaccgcagg cccctgtact
      121 ggtcatcttt tattataccg aacggccctc aggaatccct gagcgattct ctggctccaa
      181 atcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      241 ttactgtcag gtgtgggaca caactattga tcacggctta ttcggaggag ggacccggct
      301 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005431             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:19508:14118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005431
VERSION     KCWK01005431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19508:14118"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71169.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          163 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca aacagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005432             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:22481:17320
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005432
VERSION     KCWK01005432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22481:17320"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71170.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          148 c          129 g           95 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accccgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005433             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:3348:13827
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005433
VERSION     KCWK01005433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:3348:13827"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71171.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          160 c          112 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctga agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005434             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:13527:6051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005434
VERSION     KCWK01005434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13527:6051"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71172.1"
                     /translation="DYYCSIGHSSGLYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          156 c          117 g          113 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgtctacca catacactgg taccagcaga agccagggag tcccccccgg tttcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccagtaatgc ttcagcgaac acagggattt tacgcatttc tgggctccag tctgaggatg
      361 agggtgacta ttactgttcc attggacaca gcagcggtct ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005435             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:23354:11893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005435
VERSION     KCWK01005435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23354:11893"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..266
                     /note="immunoglobulin light chain variable region"
     V_region        4..266
     V_segment       4..226
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71173.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       230..266
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           65 a           83 c           89 g           67 t
ORIGIN      
        1 acatggggga gacaatattg gaagtgaagt tgtcaactgg taccagcaga agccaccgca
       61 ggcccctgtg gtggtcatct atgctgatta tgaacggccc tcagggatcc ctgagcgatt
      121 ctctggctcc aaatcaggga acacggccac cctgaccatc agcggagtcg aggccgggga
      181 tgaggctgac tattactgtc aggtttggga catttatatt gatcatccgg tgttattcgg
      241 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      301 cccg
//
LOCUS       KCWK01005436             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:8088:10797
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005436
VERSION     KCWK01005436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8088:10797"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71174.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          166 c          120 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgctgg tggtaaaaac atttactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag cagcactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005437             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:15261:6000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005437
VERSION     KCWK01005437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15261:6000"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..251
                     /note="immunoglobulin light chain variable region"
     V_region        9..251
     V_segment       9..214
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71175.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       215..251
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           56 a           89 c           76 g           68 t
ORIGIN      
        1 acatgggtga agtcatagtg tctcctggta ccagcaagtc ccaggaacag ctcccaaact
       61 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctctca
      121 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      181 ttactgcgca gcatgggatg atagcctgag gggttacatc ttcggtgctg ggacccggct
      241 cgccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005438             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:13093:11235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005438
VERSION     KCWK01005438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13093:11235"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71176.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          141 c          136 g          103 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatatcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005439             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12209:17354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005439
VERSION     KCWK01005439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12209:17354"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..433
                     /note="immunoglobulin light chain variable region"
     V_region        88..433
     V_segment       88..396
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71177.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           92 a          159 c          110 g          110 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttga gcagtggcaa tgttggtagt
      181 tacagcatat tctggtacca gcagaagcca gggagtcctc cccggtacct tctttactac
      241 tactcagact caagtaacca ccaggactct ggagtcccca gccgcttctc tggatcgaaa
      301 gatgcttcag ccaatgcagg gcttttactg atctctgggc tccagtctga agatgaggct
      361 gactattact gtgccacatg gcacagcagc gcttcttaca tcttcggtgc tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01005440             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:7961:17627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005440
VERSION     KCWK01005440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7961:17627"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..451
                     /note="immunoglobulin light chain variable region"
     V_region        115..451
     V_segment       115..408
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71178.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       414..451
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT           93 a          158 c          128 g          110 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg gttcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agcatctggg gcccccgggc agagggtcac catctcctgc
      181 actgggagca gctccaacat cggggcgggt tattatgtat cctggtacca gcagttccca
      241 ggagcagccc ccaaactcct catctatgaa aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggtgcctca gcctccctga ccatcactgg actccaatct
      361 gacgatgagg ctgattatta ctgctcagca tgggatagca gcctgagtat caattacatc
      421 ttcggtggtg ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact
      481 ctgttcccg
//
LOCUS       KCWK01005441             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:25785:17963
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005441
VERSION     KCWK01005441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:25785:17963"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71179.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           92 a          160 c          113 g          108 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca ggccttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggg ggggggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005442             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:15278:20479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005442
VERSION     KCWK01005442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15278:20479"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71180.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          148 c          130 g           96 t
ORIGIN      
        1 ccatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005443             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22961:3837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005443
VERSION     KCWK01005443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22961:3837"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..448
                     /note="immunoglobulin light chain variable region"
     V_region        115..448
     V_segment       115..411
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71181.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       412..448
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           84 a          170 c          128 g          104 t
ORIGIN      
        1 acatggggca gtgtggctgc ctcagcagag ccctgaggag tctgcaccat ggcctggacc
       61 ccaatcctcc tcctcctcct cactctcctc cttcactgca cagggtctct ctcccagcct
      121 gtgctgactc agtcgccctc tgcctctgcc tccctgggag cctcggtcaa gctcacctgc
      181 actctgagca gtggccacta cagctacacc atcgcatggc atcagcagca acaagggaag
      241 gcccctcggt tcttgatgtg gcttaagagt gatggcagcc acaccaaggg ggacggggtc
      301 cctgatcgct tctcaggctc cagctccggg gctgagcgct acctcaccat ctccaacctc
      361 cggtctgagg atgaggctga ttattactgt cagacctggg acattggcat ttgggtattc
      421 ggcggaggga cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01005444             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:21590:20750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005444
VERSION     KCWK01005444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21590:20750"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71182.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       394..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          148 c          120 g          106 t
ORIGIN      
        1 acatggggag ctgtgggctc agaagcagaa ctctgggtcc tctccaccat ggcctggacc
       61 cctcccctgc tcatcctcct cactctctgc acaggttccg tggtttcctc tgagctgact
      121 caggagcctg cattgtctgt ggccttggga caaacagtca ggatgacctg ccaaggagac
      181 agcctcaaaa cctattatgc aagctggtac cagcagaagc caggccaggt ccctgtgctg
      241 gtcatctatg gtaacaacta ccggccctca gggatcccag gccgattctc tttctcctgg
      301 tcaggaaaca caggttcctt gaccatcact gcggctcagg tggaagatga ggctgactat
      361 tactgtaagt cctgggacag cagtggtacc cattacatct tcggtgctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01005445             501 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:15244:13240
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005445
VERSION     KCWK01005445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 501)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15244:13240"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    133..463
                     /note="immunoglobulin light chain variable region"
     V_region        133..463
     V_segment       133..426
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <388..>435
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71183.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       427..463
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        464..>501
                     /gene="IGLC"
BASE COUNT          101 a          158 c          131 g          111 t
ORIGIN      
        1 acatggggga gagatttggg tgaagcgcag cttcagctgt gggtacagaa ggcaggactc
       61 aggacaatct ccagcatggc ctggttccct ctcgtcctca ccctcctcac tcactgtgca
      121 gggtcctggg cccagtctgt gctgactcag cctccctcag cgtctgaggc cgccaggaag
      181 agtgtcacca tctcctgttc tggaagcagc tccaacatcg gaagtaataa tgtgtcctgg
      241 taccagcacc tcccaggaac agctcccaaa ctcctcatct actataatga tcaacgaggc
      301 tcaggtgtct ctgaccgatt ctctggctcc aagtctggca cgtcagcctc cctggccatc
      361 agtgggctcc agaccgagga tgaggctgat tattactgcg cagcgtggga tgatagactg
      421 agcagttaca tcttcgctgc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc
      481 cccacggtca ctctgttccc g
//
LOCUS       KCWK01005446             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:16822:16966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005446
VERSION     KCWK01005446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16822:16966"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71184.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          138 c          138 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcaggc
      121 accctcgatt tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 gtatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacatgaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005447             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:4072:10607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005447
VERSION     KCWK01005447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4072:10607"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71185.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       403..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          157 c          126 g          102 t
ORIGIN      
        1 acatgggggc tgtggctcag gaagcagagc ctggagcgtc tccaccatgg cctgggctcc
       61 actcctcctc accctcctcg ctcactgcac agggtcttgg gctgaggttc tgttcacgca
      121 gccccattct gtgtcggggt ctccggggca gacggtcacc atctcctgta cccgcagcag
      181 aggcaacatt gacaatagtt atgtacagtg gtaccagcag cgcccggaca gtgccccgac
      241 cacagtgatt tacagagata accaaagagc ctctggggtc cctgatcggt tctctggctc
      301 catcgacagc tcctccaact ctgcctccct caccatctct gggctgaagt ctgaggacga
      361 ggctgactac tactgtcagt ctactgatgg caactacaat cggttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005448             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:8815:3924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005448
VERSION     KCWK01005448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8815:3924"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71186.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           89 a          147 c          128 g           97 t
ORIGIN      
        1 atgggggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtcaaag tgtacactgg taccagcaca agccaccgca ggcccctgtt ctgctcatct
      241 tttattatac cgaacggccc tcaggaatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cacaactatt gatcacggct tgttcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005449             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:18231:14215
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005449
VERSION     KCWK01005449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18231:14215"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..443
                     /note="immunoglobulin light chain variable region"
     V_region        115..443
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71187.1"
                     /translation="DYYCAAWDNTLSGVFF"
     J_segment       409..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>483
                     /gene="IGLC"
BASE COUNT           92 a          152 c          125 g          114 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcttg ggcccagtct
      121 gtgttgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca actccaacat cggaagtaat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca gactcctcat ttattttaat gatcaacgta cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcactgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gataatacct tgagcggtgt gtttttcgga
      421 ggagggaccc ggctgaccgt cctgggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01005450             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:22026:11793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005450
VERSION     KCWK01005450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22026:11793"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71188.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          141 c          136 g          102 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaagccac cgcaggcccc tgtggtggtc
      241 atctgtgctg attatgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005451             359 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:16907:13076
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005451
VERSION     KCWK01005451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 359)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 359)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:16907:13076"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..321
                     /note="immunoglobulin light chain variable region"
     V_region        8..321
     V_segment       8..284
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <252..>293
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71189.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       288..321
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        322..>359
                     /gene="IGLC"
BASE COUNT           77 a          108 c           96 g           78 t
ORIGIN      
        1 acatgggtgc atccccggga gcatcggcca gactcccctg caccctgagc agtgacctca
       61 gtgttggtag taaaaacatg tactggtacc agcagaagcc agggagcgct cccaggttat
      121 tcctgtacta ctactccgac tcagacaagc agctgggacc tggggtcccc aatcgagtct
      181 ctggctccaa ggagacctca aataacacag cgtttttgct catctctggg ctccagcctg
      241 aggacgaggc cgattattac tgtcaggtgt atgacagtag tgctgtatta ttcggaggag
      301 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005452             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:12520:3383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005452
VERSION     KCWK01005452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12520:3383"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71190.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       395..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT          100 a          137 c          125 g          105 t
ORIGIN      
        1 acatgggggg ctgtggttct aggaggaaga gctctgggtg tctcaccatg acctggacca
       61 ctgttctgct cccctttctc actctctgca caggctctga ggcctcctat gaggtgacac
      121 agtcaccctc agtgtcagtg tccccaggac agacggccag gatcacctgc tctggagcaa
      181 ttctggcaaa taattatgct cagtggttcc agcagaagcc agaccaggcc cctgtgttgg
      241 tgatatataa agacactgag aggccctcag ggatccctga gcgattctct agctccagtt
      301 cagggacaac agttaccttg accatcagtg gggcccaggc agaagatgag gctgactatt
      361 actgtcaatc agttgacagc agtgcccatc atccgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005453             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:19847:4454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005453
VERSION     KCWK01005453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19847:4454"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71191.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          161 c          124 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 catttctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgcgaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005454             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:8667:20419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005454
VERSION     KCWK01005454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8667:20419"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71192.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          156 c          118 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtatcagc agaagccagg gagtcctccc cggcatcttc
      241 tgagatacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tacttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagtagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005455             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:26386:4975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005455
VERSION     KCWK01005455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:26386:4975"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..398
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71193.1"
                     /translation="DYYCSSYAGSNTHWLF"
     J_segment       408..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           88 a          159 c          120 g          109 t
ORIGIN      
        1 acatggggtg gggtctcagg aggcagcgct ctcaggacgt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctccctc tgtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggttat aactatgtct cctggtacca gctacaccca ggcaaagccc
      241 ccaaactcat gatttatgat gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaaatc tgacaacacg gcctccctga ccatctctgg gctccaggct gaggatgaga
      361 ctgattatta ctgcagctca tatgcaggca gcaacactca ttggcttttc ggcggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005456             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:21785:8828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005456
VERSION     KCWK01005456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21785:8828"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71194.1"
                     /translation="DYYCCSYRTGNSWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          156 c          126 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccaa cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattat tgttgctcat ataggactgg aaacagttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005457             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:15597:11971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005457
VERSION     KCWK01005457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15597:11971"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71195.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          156 c          123 g          108 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata atgtgtcctg gtaccagcac ctcccaggaa
      241 cagctcccaa actcctcatc tattataatg atcaacgagg ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcgtggg atgatagcct gagcagttac atcttcgctg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01005458             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:16533:8418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005458
VERSION     KCWK01005458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16533:8418"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71196.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          162 c          121 g          111 t
ORIGIN      
        1 atgggggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggtg gtaaaaacat gtactggtac cagcagaagc cagggcgcgc tcccaggttt
      241 ttcctgtact acaactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattatta ctgtcacgta tatgacagta gtactaatgt gttattcgga
      421 ggagggaccc gtctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01005459             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:15491:12480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005459
VERSION     KCWK01005459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15491:12480"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71197.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          155 c          121 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca gccggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005460             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:16100:20400
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005460
VERSION     KCWK01005460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16100:20400"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71198.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          101 a          137 c          124 g          104 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg aggtgacaca
      121 gtcaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagcaat
      181 actggcaaat aattatgctc agtggttcca gcagaagcca gaccaggccc ctgtgttggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gttgacagca gtgcccatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005461             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:16846:12855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005461
VERSION     KCWK01005461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16846:12855"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71199.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          157 c          118 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt gacatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagtcagg gagtcctccc cggtatcttc
      241 taagatacaa atcagactca gatcagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcg aacacgggga ttttacacgt ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005462             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:20878:17030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005462
VERSION     KCWK01005462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20878:17030"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..447
                     /note="immunoglobulin light chain variable region"
     V_region        115..447
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71200.1"
                     /translation="DYYCAAWDDSLSGYYIF"
     J_segment       411..447
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>486
                     /gene="IGLC"
BASE COUNT           94 a          157 c          124 g          111 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtgtcct ggtaccagca actcccagga
      241 acgcctccca aactcctcat ctattttaat gatcagcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta ttacatcttc
      421 ggtgctggga cccggctcac cgtcctaagt cagcccaagg cttcccccac ggtcactctg
      481 ttcccg
//
LOCUS       KCWK01005463             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:10714:1983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005463
VERSION     KCWK01005463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:10714:1983"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71201.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          145 c          140 g           93 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccag cgcacgcccc tgtgctggtc
      241 atctatgcta atagcgaacg gccctcaggg gtccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg ggggtgaggc tgactattac
      361 tgtcaggtgt gggacatgcg tagtgatcaa ccgctattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005464             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:12415:19659
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005464
VERSION     KCWK01005464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12415:19659"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71202.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           86 a          158 c          126 g          101 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagttca cctgcactct gagcagtgga
      181 cacaggagct acaccatcgc gtggcatcag cagcagcaag ggaaggcccc tcgatacttg
      241 atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt attgtcagac gtgggatatt ggcatttggg tgttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005465             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:24498:10827
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005465
VERSION     KCWK01005465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24498:10827"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71203.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          108 a          135 c          122 g           98 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgacc tgacacagcc
      121 accctcagtg tcagtgtccc cagggcagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatactcagt ggttccagca gaagtcaggc cagggcccta gactggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacagtc accttgacca tcagcggggc ccagacagaa gatgaggctg actattactg
      361 tcaatcagca gacagaagtc ctaatcatgt gtttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005466             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:25181:14260
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005466
VERSION     KCWK01005466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:25181:14260"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71204.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           94 a          160 c          120 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcaga tgtatgacag tagtgatgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005467             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:16437:4551
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005467
VERSION     KCWK01005467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16437:4551"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71205.1"
                     /translation="DYYCQVWDTTLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          150 c          129 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgctctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005468             329 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18092:4722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005468
VERSION     KCWK01005468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 329)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18092:4722"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..291
                     /note="immunoglobulin light chain variable region"
     V_region        9..291
     V_segment       9..254
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71206.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       255..291
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>329
                     /gene="IGLC"
BASE COUNT           73 a           91 c           99 g           66 t
ORIGIN      
        1 acatgggggg acagacggcc aggatcacct gtgggggaga caatattgga agtaaaaatg
       61 tgcactggta ccagcaggag ccaccgcagg cccctgtgtt ggtcatcttt tatgataaca
      121 aacggccctc agggatccct gagcgattct ctggctccaa atcagggaac atcgccaccc
      181 tgaccatcag cgaggccgag gccggggatg aggctgacta ttactgtcag ctgtgggaca
      241 gtagtgttga tcatggctta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      301 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005469             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:7303:24030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005469
VERSION     KCWK01005469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:7303:24030"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71207.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       403..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          157 c          121 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca cgaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtggccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg ttcgcttctc
      301 tggctccaag tccggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttgttcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005470             275 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:21180:10692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005470
VERSION     KCWK01005470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 275)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21180:10692"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..237
                     /note="immunoglobulin light chain variable region"
     V_region        10..237
     V_segment       10..199
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <162..>209
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71208.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       205..237
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        238..>275
                     /gene="IGLC"
BASE COUNT           53 a           85 c           86 g           51 t
ORIGIN      
        1 acatggggaa ctggtaccag cggaagccag cgcaggcccc tgtgctggtc atctatgctg
       61 atagcgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca gggaacacgg
      121 ccaccctgac catcagcggg gtcgaggccg ggggtgaggc tgactattac tgtcaggtgt
      181 gggacatgcg tagtgatcaa ccgctattcg gcggagggac ccggctaacc gtcctaggtc
      241 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005471             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:21075:16351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005471
VERSION     KCWK01005471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21075:16351"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71209.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       391..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           89 a          138 c          139 g           96 t
ORIGIN      
        1 acatggggga ctttgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctttacaggc tctgcggcct cctatgaggt gactcagcca
      121 cgctcagtgt ccgtgtcccc cggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtaaaa gtgtgcagtg gtaccagcag acgccaccgc aggcccctgt actggtcatt
      241 tatggtgata gggaacggcc ctcagggatc cctgagcgat tctctggctc caactcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg atagtagtag taaatatgta ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005472             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:16640:16482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005472
VERSION     KCWK01005472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16640:16482"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71210.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          149 c          135 g           92 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gactctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta aatatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
      241 atctatgcag ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg ggtatgaggc tgactatttc
      361 tgtcaggtgt gggacgatag tagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005473             363 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:25282:12772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005473
VERSION     KCWK01005473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 363)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:25282:12772"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..325
                     /note="immunoglobulin light chain variable region"
     V_region        8..325
     V_segment       8..288
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <253..>297
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71211.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       289..325
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        326..>363
                     /gene="IGLC"
BASE COUNT           80 a          114 c           89 g           80 t
ORIGIN      
        1 acatgggcag caactcctgg agcatcagcc agtctcacat gcaccttcag cggtggcatc
       61 aatgttgctg cctaccacat acactggtac cagcagaagc cagggagtcc cccccggtat
      121 cttctgagtt acaaatcaga ctcagataag ggccaggggt ctggagtcgc cagccgcttc
      181 tctggatcca aaaatgcttc aacgaacaca ggcattttac acatctctgg gctccagtct
      241 gaggatgagg ctgactattt ctgtgccatt ggacacagca gcggtcctta catcttcggt
      301 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      361 ccg
//
LOCUS       KCWK01005474             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:15209:20311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005474
VERSION     KCWK01005474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15209:20311"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71212.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          162 c          122 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agtagtgacc
      181 tcagtgttgg tagtaaaaac atctactggt accagctgaa gccagggagc gctcccaggt
      241 cattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggtcgattat tactgtcagg tctatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005475             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:18579:9725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005475
VERSION     KCWK01005475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18579:9725"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71213.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          160 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacga tagtgctgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005476             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:9930:10822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005476
VERSION     KCWK01005476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9930:10822"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..229
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <197..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71214.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       232..269
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           64 a           91 c           83 g           69 t
ORIGIN      
        1 acatggggtt gttggctacc acatacactg gtaccagcag aagccaggga gtcctccccg
       61 gtatcttctg agatacaaat cggactcaga taagggccag ggctctggag tccccagccg
      121 cttctctgga tccaaagatg cttcagcgaa cgcagggatt ttacgcatct ctggactcca
      181 gtctgaggat gaggctgact attactgtgc cattgggcac agcagcggtg attacatctt
      241 cggtgctggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      301 gttcccg
//
LOCUS       KCWK01005477             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:15287:16216
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005477
VERSION     KCWK01005477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:15287:16216"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..449
                     /note="immunoglobulin light chain variable region"
     V_region        116..449
     V_segment       116..412
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71215.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       415..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           94 a          159 c          132 g          102 t
ORIGIN      
        1 acatgggaac gcagagtaca tggggggctc aggaagcaga gcctggagcg tctccaccat
       61 ggcctgggct ccactcctcc tcaccctcct cgctcactgc acagggtctt gggctgaggt
      121 tctgttcacg cagccccatt ctgtgtcggg gtctccgggg cagacggtca ccatctcctg
      181 tacccgcagc agaggcaaca ttgacaatag ttatgtgcag tggtaccagc agcgcccggg
      241 cagtgccccg accacagtga tttacagaga taaccaaaga gcctctgggg tccctgatcg
      301 gttctctggc tccatcgaca gctcctccaa ctctgcctcc ctcaccatct ctgggctgaa
      361 gtctgaggac gaggctgact actactgtca gtctactgat ggcaactaca atcggttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01005478             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:3853:9003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005478
VERSION     KCWK01005478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:3853:9003"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71216.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          142 c          132 g           93 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgaac tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaattaaa actgtacact ggtaccagca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgat agtaagcggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005479             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:22597:14533
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005479
VERSION     KCWK01005479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22597:14533"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71217.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       401..435
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          156 c          121 g          108 t
ORIGIN      
        1 acatggggtg ggatctcacg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtggccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccgagtc cggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt gttcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005480             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11135:4226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005480
VERSION     KCWK01005480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11135:4226"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71218.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          155 c          123 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaataa tgtgtcctgg taccagcacc tcccaggaac
      241 agctcccaaa ctcctcatct attataatga tcaacgaggc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcgtggga tgataggctg agcagttaca tcttcgctgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01005481             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:20711:14790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005481
VERSION     KCWK01005481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20711:14790"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71219.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       402..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           85 a          154 c          122 g          112 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggttcaggct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacga
      181 gcagtgatat tggctattat aacgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 ccaaactcat catttttgac gtcattaagc ggccctcagg ggtctctgat cgcttcgctg
      301 cctccaagtc tggcgacacg gcctccctga ccatctctgg gctccgggct gaggatgagg
      361 ctgattatta ctgcagctca tatgccggca gaaataattt tttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005482             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:25530:5534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005482
VERSION     KCWK01005482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:25530:5534"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..389
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71220.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           87 a          156 c          119 g          109 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 actccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgatgttg ggtattatca tgctgtgtct tggtaccagc atcatccagg caaagccccc
      241 aaactcatga tttatgaggt caataaacgg cccgcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccagactga ggatgaggct
      361 gattattact gcagctcata tgcaggcagc aacgctttat tcttcggacg agggacccgc
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005483             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:25774:18337
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005483
VERSION     KCWK01005483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25774:18337"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71221.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          148 c          130 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ctctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005484             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:18544:15468
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005484
VERSION     KCWK01005484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18544:15468"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71222.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          154 c          116 g          102 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta acaatgtgtc ctggtaccag cacctcccag gaacagctcc caaactcctc
      241 atctattata atgatcaacg aggctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcgt gggatgatag cctgagcagt tacatcttcg ctgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005485             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:25882:11880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005485
VERSION     KCWK01005485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:25882:11880"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71223.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       396..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          144 c          143 g           93 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgcg ggggagacaa
      181 gattggaagt gaagttgtga actggtacca gcggaagcca gcgcaggccc ctgtgctggt
      241 catctatgct gatagcgaac ggccctcagg gatccctgag cgattctctg gctccaaatc
      301 agggaacacg gccaccctga ccatcagcgg ggtcgaggcc gggggtgagg ctgactatta
      361 ctgtcaggtg tgggacatgc gtagtgatca accgctattc ggcggaggga cccggctaac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005486             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:14624:11737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005486
VERSION     KCWK01005486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14624:11737"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71224.1"
                     /translation="DYYCAAWDDRLTGYVF"
     J_segment       415..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          157 c          126 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cgggagcaat agtgtatcct ggtaccaggt gctcccagaa
      241 acggctccca aactcctcat ctattataat aatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatcgcc tgaccggtta cgtattcggt
      421 gttgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005487             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:14778:2021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005487
VERSION     KCWK01005487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14778:2021"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71225.1"
                     /translation="DYYCSAWDSSLTGGFF"
     J_segment       406..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          154 c          123 g          108 t
ORIGIN      
        1 acatgggggg cttcagctgt ggctagagaa gacaggactc aggacaatct ccagcatggc
       61 ctgcttccct ctcatcctca ccgtcctcac tcactgtgca ggatcctggg cccagtctgt
      121 gctgactcaa ccaccctcag cgtctggggc ccccgggcag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaatta tgtatactgg taccagcagt tctcagggaa
      241 ggcccccaaa ctcctcatcc ataataataa tcagcgaccc tcagggttcc ctgatcgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggacatc agtgggctcc agtccgagga
      361 tgaggctgat tattactgct cagcatggga tagcagtctg accggtggct ttttcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01005488             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:9197:12405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005488
VERSION     KCWK01005488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9197:12405"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71226.1"
                     /translation="DYYCCSYRSGPTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           81 a          156 c          128 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttata atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 caaactcctg atttatgatg tgaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaagacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctgctcat ataggagtgg acccacttgg gttttcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005489             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:20912:19631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005489
VERSION     KCWK01005489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20912:19631"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71227.1"
                     /translation="AYYCQVWDSDSDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          151 c          129 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta attttgtgca ctggtaccag cagaagccag cgcaggcccc tatgcaggtc
      241 atctatgctg ataccaaacg gccctcaggg atccctgaca gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgcctattac
      361 tgtcaggtgt gggacagtga tagtgatcat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005490             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:15896:11367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005490
VERSION     KCWK01005490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15896:11367"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..421
                     /note="immunoglobulin light chain variable region"
     V_region        103..421
     V_segment       103..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71228.1"
                     /translation="DYYCQVWDSDSKWVF"
     J_segment       388..421
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>462
                     /gene="IGLC"
BASE COUNT           91 a          147 c          135 g           89 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcag tgtcagcggc ctcaggacag acggccagga tcacctgtgg cggggacagc
      181 cttggaacaa aatatgtgca ctggtaccag cagaagccaa cgcaggcccc tgtggtggtc
      241 atctatgctg ataataaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtga tagtaagtgg gtcttcggcg gagggacccg gctaaccgtc
      421 ccaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005491             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:26862:11505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005491
VERSION     KCWK01005491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:26862:11505"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71229.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          140 c          131 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcctatgatc tgactcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccaaca gaagccaccg caggcccctg ttttggtcat
      241 ctatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccgga gatgaggctg actattattg
      361 tcaggtgtgg gaccttaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005492             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:13567:18267
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005492
VERSION     KCWK01005492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:13567:18267"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71230.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          150 c          122 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgta
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctctt gttctggaag catctccagc
      181 attggaagta gtgatgtatg ttggtaccag caactcccag gaacggcccc caaactcctc
      241 atcaattata gtgatcagcg actctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag ccaccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcct gggatagcag cctgagcagt ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005493             383 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:15730:19775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005493
VERSION     KCWK01005493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 383)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 383)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15730:19775"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    24..345
                     /note="immunoglobulin light chain variable region"
     V_region        24..345
     V_segment       24..309
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <273..>317
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71231.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       313..345
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        346..>383
                     /gene="IGLC"
BASE COUNT           85 a          114 c          110 g           74 t
ORIGIN      
        1 acatgggcac aggctctgcg acctcctatg aactgactca gtcaccctca gtgtcagcgg
       61 cctcaggaca gccggccagg atcacctgtg ggggagacaa cattggaatt aaaactgtac
      121 actggtacca gcagaagcca ccgcagggcc ctgtattggt catctttgct gatagtaagc
      181 ggcccacagg gatccctgag cgattctctg gctccaactc agggaacacc gccaccctga
      241 ccatcagcag ggtcgaggcc ggggatgagg ctgactatta ctgtcaggtg tgggacagta
      301 gtagtaaatg gatattcggc ggggggaccc ggctaaccgt cctaggtcag cccaaggctg
      361 ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005494             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:8530:23073
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005494
VERSION     KCWK01005494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:8530:23073"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    70..397
                     /note="immunoglobulin light chain variable region"
     V_region        70..397
     V_segment       70..357
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <319..>369
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71232.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       361..397
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        398..>435
                     /gene="IGLC"
BASE COUNT           83 a          135 c          121 g           96 t
ORIGIN      
        1 acatgggcag ccatggcctg gacttttctc ctcctcggcc tccttgctta ctgcacaggc
       61 tctgcggcct cctatgatct gactcagcca ccctcggtgt cagtgtcccc aggacagacg
      121 gccaggatca cctgtggggg agacaacatt ggaagtgaag ttgtcaactg gtaccaacag
      181 aagccaccgc aggcccctgt ggtggtcatc tatgctgatt atgaacggcc ctcagggatc
      241 cctgaccgat tctctggctc caaatcaggg aacacggcca ccctgaccat cagcggagtc
      301 gcggccgggg atgaggctga ctattactgt caggtttggg acatttatac tgatcatccg
      361 gtgttgttcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      421 gtcactctct tcccg
//
LOCUS       KCWK01005495             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:20741:8077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005495
VERSION     KCWK01005495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20741:8077"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71233.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          137 c          141 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcaggc
      121 accctcgatt tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgag gttgtgaact ggtaccagca gaaggcaccg caggcccctg tgttggtcat
      241 gtatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacatgaata gtcatcatct gttgttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005496             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10736:11271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005496
VERSION     KCWK01005496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10736:11271"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..410
                     /note="immunoglobulin light chain variable region"
     V_region        80..410
     V_segment       80..373
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <338..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71234.1"
                     /translation="GYYCTSFAGTNTDLI"
     J_segment       376..410
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>448
                     /gene="IGLC"
BASE COUNT           87 a          150 c          110 g          101 t
ORIGIN      
        1 acatgggggg gacatctcca ccatggcctg ggatctgctc ctcttcaccc tcctcactca
       61 gggcacagga tcctgggctc aggctgccct gactcagcct ccctcaatgt ctgggtctcc
      121 tggacagtcg gtcaccatct cctacactgg aaccagcagt gacattggtg gttataaccg
      181 tgtctcctgg taccaacagc acccaggcaa agcccccaaa ttcatgattt atgaggtcag
      241 tcaacggccc tcaggggtct ctgaccgtat ctctggctcc aagtctggca acacggcctc
      301 cctgaccatc tctgggctcc agactgagga tgaggctggt tattactgca cctcatttgc
      361 aggtaccaac actgacttaa tcggtggagg gacccggctg accgtcctag gtcagcccaa
      421 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005497             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:8003:5727
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005497
VERSION     KCWK01005497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8003:5727"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71235.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       414..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           92 a          157 c          129 g          110 t
ORIGIN      
        1 acatggggga agcgcagctt cagctgtggg tacagaaggc aggactcagg acaatctcca
       61 gcatggcctg gttccctctc gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc
      121 agtctgtgct gactcagcct ccctcagcgt ctgaggccgc caggaagagt gtctccatct
      181 cctgttctgg aagcagctcc aacatcggaa gtcatagtgt ctcctggtac cagcaagtcc
      241 caggaacagc tcccaaactc ctcatctatt atagtgatca acgagcctca ggtgtctctg
      301 accgattctc tggctctcag tctggcacgt cagcctccct ggccatcagt gggctccaga
      361 ccgaggatga ggctgattat tactgcgcag catgggatga tagcctgagg ggttacatct
      421 tcggtgctgg gacccggctc gccgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCWK01005498             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:21246:16651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005498
VERSION     KCWK01005498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21246:16651"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71236.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          158 c          126 g          102 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctcctct
       61 cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc tgacgcagcc
      121 gccctcagtg tctggggcgc ccgggcagag ggtcaccatc tcctgctcgg ggagcagctc
      181 caacatcggg gcgggttatt ttctccactg gtaccagcag cttccaggaa cggcccccaa
      241 actcctcatc tatgaaaata ataagcgacc ctcaggggtt tctgatcgat tctctggctc
      301 caagtctggt acctcagcct ccctgaccat cactggactc cagtctgagg atgaggctga
      361 ttattactgc cagtcctatg acagcagcct gagtgctcgg gtattcggcg gagggacccg
      421 gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005499             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:8329:16966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005499
VERSION     KCWK01005499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8329:16966"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71237.1"
                     /translation="DYYCAAWDNSLSSYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          153 c          115 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta ataatgtgtc ctggtaccag cacctcccag gaacagctcc caaactcctc
      241 atctattata atgatcagcg agactcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcgt gggataatag cctgagcagt tacatcttcg ctgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005500             367 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12660:15427
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005500
VERSION     KCWK01005500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 367)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12660:15427"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    140..329
                     /note="immunoglobulin light chain variable region"
     V_region        140..329
     V_segment       140..292
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <257..>301
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71238.1"
                     /translation="DYYCAIWHSSASYIF"
     J_segment       293..329
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        330..>367
                     /gene="IGLC"
BASE COUNT           65 a          131 c           84 g           87 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcttctccgg gagcatcagt cagactcaac ttaccaccag ggctctggag tccccagccg
      181 cttctctgga tccaaagatg cttcagccaa tgcagggctt ttactgatct ctgggctcca
      241 gtctgaagat gaggctgact attactgtgc catatggcac agcagcgctt cttacatctt
      301 cggtcctggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      361 gttcccg
//
LOCUS       KCWK01005501             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:16012:15723
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005501
VERSION     KCWK01005501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16012:15723"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71239.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          160 c          121 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaggtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcaga tgtatgacag tagtgatgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005502             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:20875:17766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005502
VERSION     KCWK01005502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20875:17766"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71240.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          152 c          115 g          116 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgagcagt ggcttcagta
      181 ttggtaatta caggatattc tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagctacca cacagactca gatatgcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgtttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggta ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005503             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:6303:17358
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005503
VERSION     KCWK01005503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:6303:17358"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..406
                     /note="immunoglobulin light chain variable region"
     V_region        58..406
     V_segment       58..367
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71241.1"
                     /translation="VYYCAIGHSSGLYIF"
     J_segment       369..406
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           81 a          150 c          107 g          106 t
ORIGIN      
        1 acatggggga ctcctctcct cctcctgctc ctctctcact gcacaggttc cctctccaag
       61 cctatgctga ctcagccggc ctccctctca gcatctcctg gagcatcagc cagtctcaca
      121 tgcaccttca gcggtggcat caatgttgct gtctaccacg tacactggta ccagcagaag
      181 ccagggagtc ccccccggta tcttctgagg tacaaatcag actcagataa gggccagggc
      241 tctggggtcc ccagccgctt ctctggatcc agtaatgctt cagcgaacac agggatttta
      301 cgcatttctg ggctccagtc tgaggatgag gctgtctatt actgtgccat tgggcacagc
      361 agcggtcttt acatcttcgg tgctgggacc cggctcaccg tcctaggtca gcccaaggct
      421 tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005504             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:25389:8323
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005504
VERSION     KCWK01005504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:25389:8323"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71242.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          156 c          116 g          112 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgactacca cgtacactgg tatcagcaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggcctgg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaat acagggattt tacacatctc tggtttccag tctgaggatg
      361 aggctgacta ttactgtgcc attggccacg gcagcggtga ttacatcttc gctactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005505             319 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:23415:12269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005505
VERSION     KCWK01005505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 319)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 319)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23415:12269"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..280
                     /note="immunoglobulin light chain variable region"
     V_region        9..280
     V_segment       9..244
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <206..>253
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71243.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       245..280
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        281..>319
                     /gene="IGLC"
BASE COUNT           65 a           97 c           80 g           77 t
ORIGIN      
        1 acatggggtc tcctgcactg ggagcagctc caacattgga ggttattatg tgcagtggta
       61 ccagcagctt ccaggaacgg cccccaaact cctcatctct gaaaataata agcgaccctc
      121 aggggtttct gatcgattct ctggctccca gtctggtacc tcagcctccc tgaccatcac
      181 tggactccag tctgaggatg aggctgatta ttactgccag tcctatgaca gcagcttgag
      241 tgctgtgtta ttcggaggag ggacccggct gaccgtccta agtcagccca aggctgcccc
      301 ctcggtcact ctcttcccg
//
LOCUS       KCWK01005506             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:7733:13880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005506
VERSION     KCWK01005506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7733:13880"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71244.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           86 a          163 c          123 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aaccagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta tttctgccag gtgtttgaca gtagtgttgt gttcttcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01005507             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:8637:20261
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005507
VERSION     KCWK01005507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8637:20261"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71245.1"
                     /translation="DYYCQSSHSRVNHPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT          103 a          137 c          124 g          101 t
ORIGIN      
        1 acatgggggt gtggttctag gaggaagacc tctgggtgtc tcaccatgac ctggaccact
       61 gttctgctcc cctttctcac tctctgcaca ggctctgagg cctcctatga gctgacacag
      121 ccaccctcag tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagaaaca
      181 ctggcaaaaa aatatgctca gtggttccag cagaagccag gccaggcccc tgtgttggtg
      241 atatataaag acagtgagag gccctcaggg atccctgagc gattctctag ctccagttca
      301 gggacaacag ttaccttgac catcagtggg gcccaggcag aagatgaggc tgactattac
      361 tgtcaatcat cgcacagcag ggttaatcat ccgtttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005508             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15350:20099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005508
VERSION     KCWK01005508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15350:20099"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71246.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          142 c          131 g           95 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagt ctctgcgacc tcctatgaac tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaattaaa actgtgcact ggtaccagca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgat agtaaacggc cctcggggat ccctgagcga ttctctggct ccaactcagg
      301 taacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005509             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:10633:14448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005509
VERSION     KCWK01005509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10633:14448"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71247.1"
                     /translation="DYYCCSYRSGPTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          157 c          124 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttata atggcgtctc ctggtaccaa caacactcag ggacagcccc
      241 caaactcctg atttatgatg tgaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggacgaggc
      361 tgattattac tgctgctcat ataggagtgg acccacttgg gttttcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005510             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:19788:8926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005510
VERSION     KCWK01005510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19788:8926"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71248.1"
                     /translation="GYYCSSFAGSNTGLF"
     J_segment       215..251
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           54 a           92 c           75 g           68 t
ORIGIN      
        1 acatgggggt ggttataacc gtgtctcccg gtacctacag cacccaggca aagcccccaa
       61 attcatgatt tatgaggtca gtcaacggcc ctcaggggtc tctgatcgct tctctggctc
      121 caagtctggc aacacggcct ccctgaccat ctctgggctc cagactgagg atgaggctgg
      181 ttattactgc agctcatttg caggttccaa cactggctta ttcggtggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005511             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:12547:19434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005511
VERSION     KCWK01005511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12547:19434"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71249.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           90 a          153 c          119 g          111 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggtaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005512             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:25472:5829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005512
VERSION     KCWK01005512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:25472:5829"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71250.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          149 c          116 g          109 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgtgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005513             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:23362:13458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005513
VERSION     KCWK01005513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:23362:13458"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..446
                     /note="immunoglobulin light chain variable region"
     V_region        101..446
     V_segment       101..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71251.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       413..446
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           91 a          162 c          120 g          111 t
ORIGIN      
        1 acatgggggt gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagcagtga
      181 cctcaatatt ggcaataaaa acatgtactg gtaccagcag aagccaggga gcgctcccaa
      241 gttattcctg tactactact ccgactcaga catgcagctg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtca tacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt attactgtca ggtgtatgac agtagtgctg tattattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01005514             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:8269:7264
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005514
VERSION     KCWK01005514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8269:7264"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71252.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>460
                     /gene="IGLC"
BASE COUNT           94 a          142 c          125 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaagatc acctgctctg gagatgcact
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 cgatgaggac accaaacggc cctctgggat ccctgagaga ttgtctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005515             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:13147:15422
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005515
VERSION     KCWK01005515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13147:15422"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..242
                     /note="immunoglobulin light chain variable region"
     V_region        8..242
     V_segment       8..205
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <167..>214
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71253.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       206..242
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        243..>280
                     /gene="IGLC"
BASE COUNT           56 a           87 c           73 g           64 t
ORIGIN      
        1 acatgggagt gtatcctggt accagcagct cccaggaaca gctcccaaac tcctcatcta
       61 ttatgatgat caacgagcct caggtgtctc tgaccgattc tctggctcca ggtctggcac
      121 gtcagcctcc ctggccatca gtgggctcca gaccgaggat gaggctgatt attactgcgc
      181 agcatgggat gatagcctga gaggttacat cttcggtgat gggacccggc tcaccgtcct
      241 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005516             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20106:7587
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005516
VERSION     KCWK01005516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20106:7587"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71254.1"
                     /translation="DYYCQSADTSGNHPLF"
     J_segment       392..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT          108 a          136 c          120 g          100 t
ORIGIN      
        1 acatggggtg tggttctagg aggaagagct ctgggtgtct caccatgacc tggaccactg
       61 ttctgctccc ctttctcact ctctgcacag gctctgaggc ctcctatgaa ctgacacagc
      121 caccctcagt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagaaatac
      181 tggcaaaaaa atatgctcag tggttccagc agaagccagg ccaggcccct atactggtaa
      241 tatataaaga cagtgagagg ccctcaggga tccctgagcg attctctagc tccagttcag
      301 ggacaacagt ttccttgacc atcagtgggg cccaggcaga agatgaggct gactattact
      361 gtcaatcagc agacaccagt ggtaatcatc cgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005517             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:17285:14322
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005517
VERSION     KCWK01005517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17285:14322"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71255.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          156 c          120 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacgtacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggttctgg ggtccccagc cgcttctctg
      301 gatccagtaa tacttcagcg aacacaggga ttttacgcgt ttctgggatc cagtctgagg
      361 atgaggctga ctattactgt gccattgggc acagcagcgg tctttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005518             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:11768:13084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005518
VERSION     KCWK01005518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11768:13084"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..403
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71256.1"
                     /translation="DYHCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           98 a          161 c          114 g          106 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagtcagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacacacac tggtaccaac agaagccagg gagtcccccc cggtttcttc
      241 tgagatacaa atcagacaca gacaagggcc aggggtctgg agtccccagc cgcttctctg
      301 gatccaaaga tacttcagcg aacacaggca ttttagacat ctctgggctc cagtctgagg
      361 atgaggctga ctatcactgt gccattggtc acagcagcgg tccatacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005519             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:18186:15061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005519
VERSION     KCWK01005519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18186:15061"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71257.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           98 a          141 c          130 g           91 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatgct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgagc tgactcaggc
      121 accctcagtg tcagcggcct caggacagac ggccaggatc acctgtggcg gagacaacat
      181 tggaattaaa aatgtccact ggtaccagca gaagccagca caggcccctg tggtagtcat
      241 ctatgctgat aacaaacggc cctcagggat ccctgagcga ctctctggct ccaactcagg
      301 gaatattgcc accctgacca tcagcagggt cgaggccggg gatgaggcag actattactg
      361 tcaggtgtgg gacagtagta gtaaatgggt attcggcgga gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005520             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20327:15312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005520
VERSION     KCWK01005520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20327:15312"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71258.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          164 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acccggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005521             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:10265:11552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005521
VERSION     KCWK01005521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:10265:11552"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71259.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          161 c          116 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat actgactcag ccggcctccc
      121 tctctgcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatataa atcagactca gataaggacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcctcagcg aacacggggc ttttgcgcat ctctgggctc cagtctgagg
      361 atgaggctga ctactactgt gccattggac acagcagcgg tgattacatc ttcggtgctg
      421 ggacccgcct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005522             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:17984:6293
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005522
VERSION     KCWK01005522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17984:6293"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..453
                     /note="immunoglobulin light chain variable region"
     V_region        123..453
     V_segment       123..416
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71260.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       417..453
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           92 a          158 c          125 g          116 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactt cacagttcca gggtcctggg
      121 cccagtctgt gctgacgcag ccgccctcag tgtctggggc gcccgggcag agggtcacca
      181 tctcctgcac tgggagcagc tccaacattg gagattattt tgtgcagtgg taccagcacc
      241 ttccaggaac ggcccccaaa ctcctcatct atgaaaataa taagcgaccc tcagggattt
      301 ctgatcgatt ctctggctcc cagtctggaa cctcagcctc cctgaccatc actggactcc
      361 agtctgagga tgaggctgat tattactgcc agtcctatga cagcagtttg attgctgtgt
      421 tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      481 ctctcttccc g
//
LOCUS       KCWK01005523             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:28377:10939
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005523
VERSION     KCWK01005523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:28377:10939"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..262
                     /note="immunoglobulin light chain variable region"
     V_region        4..262
     V_segment       4..225
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <188..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71261.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       227..262
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        263..>301
                     /gene="IGLC"
BASE COUNT           67 a           90 c           83 g           61 t
ORIGIN      
        1 acatggggga gacaacattg gaagtcaaag tgtgcactgg taccagcaca agccaccgca
       61 ggcccctgtt ctggtcatct tttattatac cgaacggccc tcaggaatcc ctgagcgaat
      121 ctctggctcc aaatcaggga acaccgccac cctgaccatc agcggggtcg aggccgggga
      181 tgaggctgac tattactgtc aggtgtggga cacaagtctt gatcacggct tatttggagg
      241 agggacccgg ctgaccgtcc taagtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01005524             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:7314:9157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005524
VERSION     KCWK01005524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7314:9157"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..426
                     /note="immunoglobulin light chain variable region"
     V_region        108..426
     V_segment       108..391
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71262.1"
                     /translation="DYYCQVWDSDSKWVF"
     J_segment       393..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>467
                     /gene="IGLC"
BASE COUNT           91 a          148 c          137 g           91 t
ORIGIN      
        1 acatgggggc tgtctgggtc tcaggaggca gcattgacgg tgcctcagcc atggcctgga
       61 cccttctcct cctcggcctc ctcgcttact gcacaggctc tgcgacctcc tatgagctga
      121 ctcagccacc ctcagtgtca gcggcctcag gacagacggc caggatcacc tgtggcgggg
      181 acagccttgg aacaaaatat gtgcactggt accagcagaa gccaacgcag gcccctgtgg
      241 tggtcatcta tgctgataat aaacggccct cagggatccc tgagcgattc tctggctcca
      301 actcagggaa caccgccacc ctgaccatca gcagggtcga ggccggggat gaggctgact
      361 attactgtca ggtgtgggac agtgatagta agtgggtctt cggcggaggg acccggctaa
      421 ccgtcccagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005525             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:13470:19053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005525
VERSION     KCWK01005525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13470:19053"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..455
                     /note="immunoglobulin light chain variable region"
     V_region        107..455
     V_segment       107..416
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71263.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       418..455
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT          100 a          156 c          120 g          117 t
ORIGIN      
        1 acatggggca gagtacatgg ggactgcagg gaaagaggct gtgtccacca tggcctggac
       61 tcctctcctc ctcctgctcc tctctcactg cacaggttcc ctctcgcagc ctgtgctgac
      121 tcagccaacc tccctctcag catctcctgg agcatcagcc agactcacct gcaccttgaa
      181 cagtggcatc agtgttggta attacaggat attctggtac caccagaagc cagggagtcc
      241 tccccggtat cttctgaact accacacaga ctcagatatt caccagggct ctggagtccc
      301 cagccgcttc tctgggtcca aggatgcttc ggccaatgca gggattttac tcatctctgg
      361 actccagtct gaggatgagg ctgactatta ctgtatgatt tggcacaaca atgcttattg
      421 ggtattcggc ggagggaccc ggctaaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01005526             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:9448:10744
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005526
VERSION     KCWK01005526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9448:10744"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71264.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          162 c          116 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctctgcatc tcctggagct tcagccagtc tcacatgcac cttcaccggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatataa atcagactca gataaggacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcctcagcg aacacggggc ttttgcgcat ctctgggctc cagtctgagg
      361 atgaggctga ctactactgt gccattggac acagcagcgg tgattacatc ttcggtgctg
      421 ggacccgcct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005527             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:13106:11406
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005527
VERSION     KCWK01005527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13106:11406"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71265.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          163 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agtagtgacc
      181 tcagtgttgg tagtaaaaac atctactggt accagctgaa gccagggagc gctcccaggt
      241 cattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tctatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005528             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:21057:3325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005528
VERSION     KCWK01005528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:21057:3325"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    15..255
                     /note="immunoglobulin light chain variable region"
     V_region        15..255
     V_segment       15..218
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <180..>227
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71266.1"
                     /translation="DYYCQSYDSNLSAMLF"
     J_segment       220..255
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        256..>293
                     /gene="IGLC"
BASE COUNT           61 a           87 c           73 g           72 t
ORIGIN      
        1 acatgggcgg ggcgggttat tatgtgcact ggtaccagca acttccagga acggccccca
       61 aactcctcat ctatgaaaac aatatgcgac cctcaggggt ttctgatcga ttctctggct
      121 ccaagtctgg tacctcagcc tccctgacca tcactggact ccagtctgag gatgaggctg
      181 attattactg ccagtcctat gacagtaatt tgagtgctat gttattcgga ggagggaccc
      241 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005529             338 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:16493:20597
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005529
VERSION     KCWK01005529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 338)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16493:20597"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..300
                     /note="immunoglobulin light chain variable region"
     V_region        8..300
     V_segment       8..263
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <228..>272
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71267.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       266..300
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        301..>338
                     /gene="IGLC"
BASE COUNT           71 a          108 c           89 g           70 t
ORIGIN      
        1 acatgggggg gcagacggtc accatctcct gtacccgcag cagaggcaac attgacaata
       61 gttatgtgca gtggtaccag cagcgcccgg gcagtgcccc gaccacagtg atttacagag
      121 ataaccaaag agcctctggg gtccctgatc ggttctctgg ctccatcgac agctcctcca
      181 actctgcctc cctcaccatc tctgggctga agtctgagga cgaggctgac tactactgtc
      241 agtctactga tggcaactac aatcggttat tcggaggagg gacccggctg accgtcctag
      301 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005530             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:7884:12793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005530
VERSION     KCWK01005530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7884:12793"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71268.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          141 c          136 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaagc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005531             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:13009:3823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005531
VERSION     KCWK01005531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13009:3823"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71269.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          158 c          124 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggcgcttata actatgtctc ctggtaccaa caacatccag acacagcccc
      241 caaactcatg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctgctcac atgcaggcag tgatattttc gtgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005532             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:15138:13909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005532
VERSION     KCWK01005532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15138:13909"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71270.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           89 a          161 c          120 g          111 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ttcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt aataaaaaca tgtactggta ccaacagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caactaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtttgacagt agtgctgtgt tgttcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01005533             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:19890:13387
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005533
VERSION     KCWK01005533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19890:13387"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71271.1"
                     /translation="DYYCQSYDSSLSGVLF"
     J_segment       412..446
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          155 c          127 g          113 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca ccatctcctg
      181 cagtgggagc aactccaaca ttggatacta ttatgtgcag tggtaccagc agcttccagg
      241 gacggccccc aaactcctca tctatgaaaa taataagcga ccctctgggg tttctgatcg
      301 attctctggc tcccagtctg gtacctcagc ctccctgacc atcactggac tccagtctga
      361 ggatgaggct gattattact gccagtccta tgacagcagt ttgagtggtg tcttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01005534             363 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:14537:3143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005534
VERSION     KCWK01005534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 363)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14537:3143"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..325
                     /note="immunoglobulin light chain variable region"
     V_region        8..325
     V_segment       8..288
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <256..>297
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71272.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       289..325
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        326..>363
                     /gene="IGLC"
BASE COUNT           74 a          113 c          100 g           76 t
ORIGIN      
        1 acatgggagt cgccctctgt ctctgcctcc ctgggagcct cggtcaaact cacctgtact
       61 ttgaacagtg ggcacagcag ctacaccatc gcatggcatc agcagcagca agggaaggcc
      121 ccccggtact tgatgtggct taaaagtgaa ggcagccata gcaaggggga cgggatccct
      181 gatcgcttct caggctccag ctccggggct gagcgctacc tcaccatctc caacctccag
      241 tctgaggatg aggctgatta ttactgtcag acctgggata ctgacattgt gttattcgga
      301 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      361 ccg
//
LOCUS       KCWK01005535             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:19835:3505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005535
VERSION     KCWK01005535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19835:3505"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71273.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          160 c          112 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt gacatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005536             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:19236:14741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005536
VERSION     KCWK01005536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:19236:14741"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71274.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           89 a          159 c          124 g          109 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc cagtctggca cgtcggcctc cctggccatc agtggcctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01005537             277 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:21671:12563
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005537
VERSION     KCWK01005537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 277)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:21671:12563"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..239
                     /note="immunoglobulin light chain variable region"
     V_region        8..239
     V_segment       8..202
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <164..>211
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71275.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       203..239
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        240..>277
                     /gene="IGLC"
BASE COUNT           55 a           83 c           81 g           58 t
ORIGIN      
        1 acatggggtg cactggtacc agcaggagcc accgcaggcc cctgtgttgg tcatctttta
       61 tgataacaaa cggccctcag ggatccctga gcgattctct ggctccaaat cagggaacat
      121 cgccaccctg accatcagcg aggccgaggc cggggatgag gctgactatt actgtcagct
      181 gtgggacagt agtgttgatc atggcttatt cggaggaggg acccggctga ccgtcctagg
      241 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005538             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:8357:13545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005538
VERSION     KCWK01005538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8357:13545"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71276.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          156 c          120 g          110 t
ORIGIN      
        1 ccatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005539             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:9538:8928
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005539
VERSION     KCWK01005539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9538:8928"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71277.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           90 a          139 c          133 g           99 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccag
      121 cctcggtgtc agtgtccccg ggacagacgg ccaggatcac ctgtggggga gacaatattg
      181 gaagtaaaaa tgtgcactgg taccagcagg agccaccgca ggcccctgtg ttggtcatct
      241 tttatgataa caaacggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acatcgccac cctgaccatc agcgaggccg aggccgggga tgaggctgac tattactgtc
      361 agctgtggga cagtagtgtt gatcatggct tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005540             346 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:5590:15453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005540
VERSION     KCWK01005540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 346)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 346)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5590:15453"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..308
                     /note="immunoglobulin light chain variable region"
     V_region        8..308
     V_segment       8..259
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <233..>280
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71278.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       271..308
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        309..>346
                     /gene="IGLC"
BASE COUNT           74 a          100 c          101 g           71 t
ORIGIN      
        1 acatgggtcg gtgtcagcgg cctcaggaca gacggccagg atcacctgtg ggggagacaa
       61 cattggaatt aaatttgtcc actggtacca gcagaagcca gcgcaggccc ctgtgaaggt
      121 catctatgct gatgacaaac ggccctcagg gatccctgag agattctctg gctccaattc
      181 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactattc
      241 ctgtcaggtg tgggacagtg agactgatta ttacatcttc ggttctggga cccggctcac
      301 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005541             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:12170:18329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005541
VERSION     KCWK01005541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12170:18329"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71279.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          162 c          111 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagttacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaaa tgcttcaaca aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005542             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:14453:24582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005542
VERSION     KCWK01005542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14453:24582"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..422
                     /note="immunoglobulin light chain variable region"
     V_region        98..422
     V_segment       98..379
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71280.1"
                     /translation="DYYCQVWDSSSDHWIF"
     J_segment       385..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          147 c          131 g           89 t
ORIGIN      
        1 acatggggtc tcaggaggca gcattgacgg tgcctcagcc atggcctgga cccttctcct
       61 cctcggcctc ctcgctcact gcacagactc tgcgacctcc tatgagctga ctcagccacc
      121 ctcggtgtca gcggcctcag gacagacggc caggatcacc tgtgggggag acaacattgg
      181 aagtaaatat gtgcactggt accagcagag gccaccgcag gcccctgtgc aagtcatcta
      241 tactgatagc agacggccct cagggatccc tgagcgattc tctggctcca actcagggaa
      301 caccaccacc ctgaccatca gcgcggtcga ggccggggat gaggctgact attactgtca
      361 ggtgtgggac agtagtagtg atcattggat attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005543             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:12901:11588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005543
VERSION     KCWK01005543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12901:11588"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..420
                     /note="immunoglobulin light chain variable region"
     V_region        90..420
     V_segment       90..383
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <345..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71281.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       384..420
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           91 a          148 c          117 g          102 t
ORIGIN      
        1 acatgggggc aggactcagg acaatctcca gcatggcctg gttccctctc gtcctcaccc
       61 tcctcactca ctgtgcaggg tcctgggccc agtctgtgct gactcagact ccctcagcgt
      121 ctgaggccgc caggaagagt gtcaccatct cctgttctgg aagcagatcc aacatcggaa
      181 gaaatagtgt atcctggtac cagaagctcc caggaacagc tcccaaactc ctcatctatt
      241 atagtgatca acgagcctca ggtgtctctg accgattctc tggctccaag tctggcacgt
      301 cagcctccct ggccatcagc gggctccagg ccgaggatga ggctgattat tactgcgcag
      361 catgggatga tagcctgagc ggttacattt tcggtgctgg gacccggctc accgtcctag
      421 gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01005544             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:13816:4403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005544
VERSION     KCWK01005544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13816:4403"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71282.1"
                     /translation="DYYCQSAENSAKYYIF"
     J_segment       399..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT          108 a          133 c          122 g          104 t
ORIGIN      
        1 acatgggggg ctgtggttct aggaggaaga gctctgggtg tctcaccatg acctggacca
       61 ctgttctgct cccctttctc actctctgca caggctctga ggcctcctat gagctgacac
      121 agccaccctc agtgtcagtg tccccaggac agacggccag gatcacctgc tctggagaaa
      181 tactggcaaa aaaatatggt cagtggttcc agcagaagcc aggtcaggcc cctgtgttgg
      241 tgatatataa agacagtgag aggccctcag ggatccctga gcgactctct agttccagtt
      301 caggaacaac acttaccttg accatcactg gggcccaggc agaagatgag gctgactatt
      361 actgtcaatc agcagagaac agtgctaagt attatatatt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01005545             353 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:16049:11580
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005545
VERSION     KCWK01005545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 353)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16049:11580"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..315
                     /note="immunoglobulin light chain variable region"
     V_region        9..315
     V_segment       9..278
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>287
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71283.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       279..315
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        316..>353
                     /gene="IGLC"
BASE COUNT           71 a          107 c           94 g           81 t
ORIGIN      
        1 acatgggggg agcatcagcc agtctcacat gcaccttcag cggtggcatc aatgttgctg
       61 tctaccacgt acactggtac cagcagaagc cagggagtcc cccccggttt cttctgaggt
      121 acaaatcaga ctcagataag ggccagggct ctggagtccc cagccgcttc tctggatcca
      181 gtaatgtttc agcgaacaca gggattttac gcatttctgg gctccagtct gaggatgagg
      241 ctgactatta ctgtgccatt gggcacagca gcggtcctta catcttcggt gctgggaccc
      301 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005546             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:13957:15377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005546
VERSION     KCWK01005546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13957:15377"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..396
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71284.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       398..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           94 a          151 c          116 g          110 t
ORIGIN      
        1 acatggggtc tggagccagg gatcccttcc aatatcagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcacctgtgc ttccagcact
      181 ggagcagtca ccagtggtca ctctccacac tggttccagc agaaacctgg acaagccccc
      241 aagacactga tttataatac aaactacaga cactcctgga ctcctgcccg gttctcaggc
      301 tccctccttg ggggtaaagc tgccctgaca ctgtcaggtg cgcagcctga ggatgaggct
      361 gagtattatt gtttactgta ctatagtggt gctcagctgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005547             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:22639:19986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005547
VERSION     KCWK01005547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22639:19986"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71285.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          155 c          126 g          112 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc ctctcctgca
      181 ctgggagcag ctccaacatt ggagattatt atgtgcagtg gtaccagcag cttccaggaa
      241 cggcccccaa actcctcatc tatgaaaata ataagcgacc ctcaggggtt tctgatcgat
      301 tctctggctc ccagtctggt acctcagcct ccctgaccat cactggactc cagtctgacg
      361 atgaggctga ttattactgt cagtcctatg atagcagcct gagtgttgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005548             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:21341:18038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005548
VERSION     KCWK01005548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:21341:18038"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71286.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       417..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           94 a          157 c          125 g          109 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg acagagggtc accatctcct
      181 gcattagcag cagctccaac atcggggcgg cttattatgt atcctggtac caacagttcc
      241 caggaacagc ccccaaactc ctcatctatg aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtccct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgtttag catgggatac cagcctgaat tggatcttcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005549             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:9681:6826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005549
VERSION     KCWK01005549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9681:6826"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    62..410
                     /note="immunoglobulin light chain variable region"
     V_region        62..410
     V_segment       62..370
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <338..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71287.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       373..410
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>448
                     /gene="IGLC"
BASE COUNT           89 a          151 c          105 g          103 t
ORIGIN      
        1 acatggggcc tggactcctc tcctcctcct gctcctctct cactgcacag gttccctctc
       61 caagcctatg ctgactcagc cggcctccct ctcagcatct cctggaacat cagccagtct
      121 cacatgcacc ttcagcggtg gcatcaatgt tgctggctac cacatacact ggtaccagca
      181 gaagccaggg agtcctcccc gatatcttct gagatacaaa tcggactcag ataagggcca
      241 gggctctgga gtccccagcc gcttctctgg atccaaagat gcttcagcga acacagggat
      301 tttacgcatc tctgggctcc agtctgagga tgaggctgac tattactgtg ccattggaca
      361 cagcagcggt gattacatct tcggtgctgg gacccggctc accgtcctag gtcagcccaa
      421 ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01005550             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:18407:14019
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005550
VERSION     KCWK01005550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18407:14019"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71288.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          148 c          130 g           97 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt caaagtgtgc actggtacca gcacaagcca ccgcaggccc ctgtactggt
      241 catcttttat tataccgaac ggccctcagg aatccctgag cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacacaa ctattgatca cggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005551             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:10879:3490
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005551
VERSION     KCWK01005551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10879:3490"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71289.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          160 c          122 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccaggctccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcaactggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcaga tgtatgacag tagtgatgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005552             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:19520:5040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005552
VERSION     KCWK01005552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19520:5040"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71290.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       401..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          154 c          112 g          115 t
ORIGIN      
        1 acaggggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcttctcc tggagcatca gccagactca cctgcacctt gaacagtggc atcagtgttg
      181 ctaattacag gatattctgg taccaccaga agccagggag tcctccccgg tatcttctga
      241 actaccacac agactcagat attcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcagggattt tactcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtatg atttggcaca acaatgctta ttgggttttc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005553             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10509:7748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005553
VERSION     KCWK01005553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10509:7748"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..455
                     /note="immunoglobulin light chain variable region"
     V_region        125..455
     V_segment       125..418
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71291.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       419..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           93 a          159 c          126 g          115 t
ORIGIN      
        1 acacggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac ttcacagttc cagggtcctg
      121 ggcccagtct gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac
      181 catctcctgc actgggagca gctccaacat tggagattat tttgtgcagt ggtaccagca
      241 ccttccagga acggccccca aactcctcat ctatgaaaat aataagcggc cctcagggat
      301 ttctgatcga ttctctggct cccagtctgg aacctcagcc tccctgacca tcactggact
      361 ccagtctgag gatgaggctg attattactg ccagtcctat gacagcagtt tgattgctgt
      421 gttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01005554             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16954:2043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005554
VERSION     KCWK01005554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16954:2043"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71292.1"
                     /translation="DYYCAAWDDGLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           86 a          157 c          128 g          110 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccgggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcgtct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatggcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcgccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01005555             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:13822:19247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005555
VERSION     KCWK01005555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13822:19247"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71293.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          146 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgtggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005556             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18460:12342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005556
VERSION     KCWK01005556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18460:12342"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71294.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       394..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          141 c          137 g          102 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactttac aggctctgtg gcctcctatg agttgcctca
      121 gccacgctca gtgtccgtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt aatagtgtgc attggtacca gcagaagcca ccgcgggccc ctgtattggt
      241 catctctgtt gatagcgaac ggccctcagg gatccctgag cgattctctg gttccagatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggataata tttataaata cgcggtattc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005557             498 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:23897:11776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005557
VERSION     KCWK01005557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 498)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:23897:11776"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..460
                     /note="immunoglobulin light chain variable region"
     V_region        112..460
     V_segment       112..420
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <388..>432
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71295.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       423..460
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        461..>498
                     /gene="IGLC"
BASE COUNT          104 a          160 c          117 g          117 t
ORIGIN      
        1 acatggggac cgcagcccga ttgtgactct tctggcaaag atccctgaaa aatttgaccc
       61 tggtttctgc cttagcaccc aataatgtct gtgtttgcag gttccctctc caagcctatg
      121 ctgactcagc cggcctccct ctctgcatct cctggagcat cagccagtct cacatgcacc
      181 ttcagcggtg gcatcaatgt tgctgcctac cacatacact ggtaccagca gaagccaggg
      241 agtcctcccc ggtatcttct gagatacaaa tcagactcag ataaggacca gggctctgga
      301 gtccccagcc gcttctctgg atccaaagat gcctcagcga acacagggat tttacgcatc
      361 tctgggctcc agtctgagga tgaggctgac tactactgtg ccattgggca cagcagcggt
      421 gattacatct tcgctgctgg gacccgcctc accgtcctag gtcagcccaa ggcttccccc
      481 acggtcactc tgttcccg
//
LOCUS       KCWK01005558             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:19512:5797
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005558
VERSION     KCWK01005558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19512:5797"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    19..349
                     /note="immunoglobulin light chain variable region"
     V_region        19..349
     V_segment       19..310
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <277..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71296.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       312..349
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>387
                     /gene="IGLC"
BASE COUNT           73 a          120 c          103 g           91 t
ORIGIN      
        1 acatgggggt cctgggccca gtctgtgttg acgcagccgc cctcagcatc tggggccccc
       61 gggcagaggg tcaccatctc ctgcactggg agcaggtcca acatcggggc gggtttttat
      121 ttttcctggt accagcagtt cccaggaaca gcccccaaac tcctcatctt tgaaaataat
      181 aagcgaccct caggggtttc tgaccgattc tctggctcca agtctggttc ctcagcctcc
      241 ctgaccatca ctggactcca atctgaggat gaggctgatt attattgttc atcatgggaa
      301 agcagcctga attgggtatt cggcggaggg acccggctga ccgtcctagg tcagcccaag
      361 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005559             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:11750:4865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005559
VERSION     KCWK01005559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11750:4865"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71297.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          140 c          136 g          102 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtgga ggagacaaca
      181 ttggaagtga agttgtcaac tggtaccagc agaggccacc gcaggcccct gtgctggtca
      241 tctatgctga ttatgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagtggag tcgaggccgg ggatgaggct gactattatt
      361 gtcaggtgtg ggacatttat attgaccatc cggtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005560             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:7624:9981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005560
VERSION     KCWK01005560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7624:9981"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..396
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71298.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       400..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           86 a          156 c          124 g          105 t
ORIGIN      
        1 acatgggggt gtggctcagg aagcagagcc tggagcatct ccaccatggc ctgggctcca
       61 ctcctcctca ccctcctcgc tcactgcaca gggtcttggg ctgaggttgt gttcactcag
      121 ccccattctg tgtcggggtc tccggggcag acggtcacca tctcctgcac ccgcagcagt
      181 ggcagcattg acaacggctt tgtgtactgg taccagcagc ggccgggcag cgctcccacc
      241 actgtgattt acaaagataa ccaaagaccc tctggggtcc ctgatcggtt ctctggctcc
      301 atcgacagct cctccaactc tgcctccctc accatctctg gactgaaatc tgaggacgag
      361 gctgactatt actgtcagtc ttatgacagc agcagtgtat tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005561             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:14234:8364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005561
VERSION     KCWK01005561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14234:8364"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..244
                     /note="immunoglobulin light chain variable region"
     V_region        7..244
     V_segment       7..210
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>220
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71299.1"
                     /translation="DYYCYSSDSNSKWLF"
     J_segment       216..244
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        245..>286
                     /gene="IGLC"
BASE COUNT           65 a           83 c           79 g           59 t
ORIGIN      
        1 acatgggcca aagaaatatg cttattggtt cccgcagaag gcaggccagc cccctatggt
       61 gatcatctat gaggacacca aacggccctc tgggatccct gagagattct ctggctccag
      121 ctcagggaca gtggccacct tgactctcag tggggcccag gtggaggatg aaggtgacta
      181 ctactgttac tcatcagaca gcaatagtaa atggctattc gacggaggga cccggctgac
      241 cgtcgtaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005562             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:15597:11572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005562
VERSION     KCWK01005562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15597:11572"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71300.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          138 c          136 g          103 t
ORIGIN      
        1 acatgggggg gcctcgggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggaaagac ggccaggatc acctgtgggg gagacaatat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tggtggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg actattactg
      361 tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005563             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:20397:22147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005563
VERSION     KCWK01005563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20397:22147"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..426
                     /note="immunoglobulin light chain variable region"
     V_region        96..426
     V_segment       96..388
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71301.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       390..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           94 a          154 c          112 g          104 t
ORIGIN      
        1 acatgggaca gaaggcagga ctcaggacaa tctccagcat ggcctggttc cctctcgtcc
       61 tcaccctcct cactcactgt gcagggtcct gggcccagtc tgtgctgact cagcctccct
      121 cagcgtctga ggccgccagg aagagtgtca ccatctcctg ttctggaagc acctccaaca
      181 tcggaagcaa taatgtatcc tggtaccagc agctcccagg aacagctccc aaactcctct
      241 tttattataa tgatcaacga gcctcaggtg tctctgaccg attctcttgc tccaagtctg
      301 gcacgtcagc ctccctggcc atcagtgggc tccagaccga ggatgaggct gattattact
      361 gcgcagcatg ggatgataac ctgagcggct acatcttcgg tgctgggacc cggctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005564             360 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:13224:7040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005564
VERSION     KCWK01005564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 360)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 360)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..360
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:13224:7040"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..322
                     /note="immunoglobulin light chain variable region"
     V_region        7..322
     V_segment       7..282
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <250..>294
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71302.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       285..322
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        323..>360
                     /gene="IGLC"
BASE COUNT           77 a          109 c           93 g           81 t
ORIGIN      
        1 acatgggcat ctcctggaac atcagccagt ctcacatgca ccttcagcgg tggcatcaat
       61 gttgttggct accacataca ctggtaccag cagaagccag ggagtcctcc ccggtatctt
      121 ctgagataca aatcggactc agataagggc cagggctctg gagtccccag ccgcttctct
      181 ggatccaaag atgcttcagc gaacgcaggg attttacgca tctctggact ccagtctgag
      241 gatgaggctg actattactg tgccattggg cacagcagcg gtgattacat cttcggtgct
      301 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005565             453 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:12106:7473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005565
VERSION     KCWK01005565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 453)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12106:7473"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..415
                     /note="immunoglobulin light chain variable region"
     V_region        85..415
     V_segment       85..379
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <343..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71303.1"
                     /translation="LYYCCSYTTSSTYIF"
     J_segment       380..415
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>453
                     /gene="IGLC"
BASE COUNT           83 a          156 c          104 g          110 t
ORIGIN      
        1 acatggggct ctcaggacgt ctccaccatg gcctggactc tgctcctcgt caccctcctc
       61 actcaaggca caggatcctg ggctcagtct gccccgactc agcctccctc tgtgtctggg
      121 tctcctggac agtcggtcac catctcctgc actggaacca gcactgacgt tggtggttat
      181 aactctgtct cctggtacca acaggaccca ggcaaagccc ccaaactcat catttatggt
      241 gtcagtaatc ggccctcagg ggtctctgat cgcttctctg gctccaagtc tggcaacacg
      301 gcctccctga ccatctctgg gctccaggct gaggacgagg ctctttatta ctgttgttca
      361 tatacaacca gtagcactta catcttcggt actgggaccc ggctaaccgt cctaggtcag
      421 cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005566             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:25922:11538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005566
VERSION     KCWK01005566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:25922:11538"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..251
                     /note="immunoglobulin light chain variable region"
     V_region        1..251
     V_segment       1..214
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71304.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       217..251
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           56 a           91 c           77 g           65 t
ORIGIN      
        1 caacatcgga agtaatagtg tttcctggta ccagcagctc ccagaaacgg ctcccaaact
       61 cctcatcttt tataatgatc ggcgagcctc aggtgtctct gaccgattct ctggctccaa
      121 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      181 ttactgcgca gcatgggatg atagcctgag cggtccggta ttcggcggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005567             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:14359:12490
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005567
VERSION     KCWK01005567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14359:12490"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71305.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          144 c          133 g           94 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gaactgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc agcagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgatagtaaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005568             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16153:19810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005568
VERSION     KCWK01005568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16153:19810"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..368
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71306.1"
                     /translation="DYYCQVWGSRSDHPVF"
     J_segment       377..411
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           84 a          145 c          128 g           92 t
ORIGIN      
        1 acatggggag cattgacggt gcctcagcca tggcctggac ccttctcctc ctcggcctcc
       61 tcgctcactg cacagtctct gcgacctcct atgaactgac tcagccaccc tcggtgtcag
      121 cggcctcagg acagacggcc agggtcacct gtggggcagg taacattgga agtaattttg
      181 ttcactggta ccagcagaag ccaccgcagg cccctgttca ggtcatctat gcagataaca
      241 gacggccctc agggatccct gagcgattct ctggctccaa ttcagggaac accgccaccc
      301 tgaccatcag cggggtcgag gccggggatg aggctgacta ttactgtcag gtgtggggca
      361 gtcgtagtga tcatccggta ttcggcggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005569             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:11916:19577
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005569
VERSION     KCWK01005569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11916:19577"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..432
                     /note="immunoglobulin light chain variable region"
     V_region        112..432
     V_segment       112..393
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71307.1"
                     /translation="AYYCQVWDSDSDHYIF"
     J_segment       399..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>474
                     /gene="IGLC"
BASE COUNT           92 a          151 c          133 g           98 t
ORIGIN      
        1 acatggggct gccctgtctg ggtctcagga ggcagcattg acggtgcctc agccatggcc
       61 tggacccttc tcctcctcgg cctcctcgct cactgcacag gctctgcgac ctcctatgag
      121 ctgactcagc caccctcggt gtcagcggcc tcaggacaga cggccaggat cacttgtggg
      181 ggagacaaca ttggaactaa ttttgtgcac tggtaccagc agaagccagc gcaggcccct
      241 atacaggtca tctatgctga tagcaaacgg ccctcaggga tccctgagag attctctggc
      301 tccaactcag ggaacaccgc caccctgacc atcagcggag tcgaggccgg ggatgaggct
      361 gcctattact gtcaggtgtg ggacagtgat agtgatcatt acatcttcgg tgctgggacc
      421 cggctcaccg tcgtaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005570             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14519:17393
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005570
VERSION     KCWK01005570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14519:17393"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71308.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          139 c          138 g           99 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 gcaccctcga tttcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atgtatgctg atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacatgaa tagtcatcat ctgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005571             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:8581:20499
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005571
VERSION     KCWK01005571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8581:20499"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71309.1"
                     /translation="DYFCQVWDSISDHPLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          149 c          133 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gcctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta aatatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgcaggtc
      241 atttatggtg ataccaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactatttc
      361 tgtcaggtgt gggacagtat tagtgatcat cccttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005572             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:10492:7394
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005572
VERSION     KCWK01005572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10492:7394"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71310.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       391..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          141 c          136 g          100 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagtc
      121 accctcgatt tcagtgtccc caggacagac ggccagggtc acctgtgggg gagacaacat
      181 cggaggtgaa gttgtgaatt ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacgcggcc accctgacca tcagcggggt cgaggccgga gatgaggctg actattactg
      361 tcaggtgtgg gaccttaata gtcatcatct cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005573             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:7154:17039
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005573
VERSION     KCWK01005573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7154:17039"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71311.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          158 c          113 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 caaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005574             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:21223:3836
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005574
VERSION     KCWK01005574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21223:3836"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..296
                     /note="immunoglobulin light chain variable region"
     V_region        4..296
     V_segment       4..258
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <221..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71312.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       260..296
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>334
                     /gene="IGLC"
BASE COUNT           73 a          102 c           95 g           64 t
ORIGIN      
        1 acatgggtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca ttggaagtca
       61 aagtgtgcac tggtaccagc acaagccacc gcaggcccct gttctggtca tcttttatta
      121 taccgaacgg ccctcaggaa tccctgagcg aatctctggc tccaaatcag ggaacaccgc
      181 caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg
      241 ggacacaagt cttgatcacg gcttattcgg aggagggacc cggctgaccg tcctaggtca
      301 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005575             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:4117:7838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005575
VERSION     KCWK01005575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4117:7838"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71313.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          148 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcaacattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttcttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005576             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:4820:17041
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005576
VERSION     KCWK01005576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:4820:17041"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71314.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          145 c          130 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tattggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctgggt ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005577             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:10130:9222
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005577
VERSION     KCWK01005577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:10130:9222"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..411
                     /note="immunoglobulin light chain variable region"
     V_region        63..411
     V_segment       63..374
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71315.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       375..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           90 a          155 c          100 g          104 t
ORIGIN      
        1 acatgggggc ctggactcct ctcctcctcc tgctcctctc tcactgcaca ggttccctct
       61 ccaagcctat gctgactcag ccggcctccc tctcagcaac tcctggagca tcagccagtc
      121 tcacatgcac cttcagcggt ggcatcaatg ttgttgccta ccacatacac tggtaccagc
      181 agaagccagg gagtcccccc cggtatcttc tgagttacaa atcagactca gataagggcc
      241 agggctctgg agtccccagc cgcttctctg gatccaaaaa tgcttcaaca aacacaggca
      301 ttttacacat ctctgggctc cagtctgagg atgaggctga ctatttctgt gccattggac
      361 acagcagcgg tccttacatc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005578             318 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:8018:21312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005578
VERSION     KCWK01005578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 318)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8018:21312"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..280
                     /note="immunoglobulin light chain variable region"
     V_region        8..280
     V_segment       8..241
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>252
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71316.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       246..280
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        281..>318
                     /gene="IGLC"
BASE COUNT           64 a           96 c           79 g           79 t
ORIGIN      
        1 acatggggtg gcatcaatgt tggttcttac accatattct ggtaccagca gaagccaggg
       61 agtcctcccc ggttccttct gtactactac tcagactcaa ataatcacca gggctctgga
      121 gtccccagcc gcttctctgg atccaaagat gcttcagcca atgcagggct tttactgatc
      181 tctgggctcc agtctgaaga tgaggctgac tattactgtg ccatgtggca cagcagcgct
      241 tatgccttat tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc
      301 tcggtcactc tcttcccg
//
LOCUS       KCWK01005579             393 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:13142:11248
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005579
VERSION     KCWK01005579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 393)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:13142:11248"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    25..355
                     /note="immunoglobulin light chain variable region"
     V_region        25..355
     V_segment       25..318
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <280..>327
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71317.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       319..355
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        356..>393
                     /gene="IGLC"
BASE COUNT           71 a          125 c          106 g           91 t
ORIGIN      
        1 acatggggtg cagggtcctg ggcccagtct gtgctgactc agcctccctc agcgtctgag
       61 gccgccggga agagtgtctc catctcctgt tctggaagca gctccaacat cggaagtcat
      121 agtgtctcct ggtaccagca gctcccagga acagctccca aactcctcat ctattatagt
      181 gatcaacgag cctcaggtgt ctctgaccga ttctctggct ctcagtctgg cacgtcagcc
      241 tccctggcca tcagtgggct ccagaccgag gatgaggctg attattactg cgcagcatgg
      301 gatgatagcc tgagcggtta catcttcggt gttgggaccc ggctcgccgt cctaggtcag
      361 cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005580             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:10259:14275
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005580
VERSION     KCWK01005580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10259:14275"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71318.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          153 c          121 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatt atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caagctcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005581             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:11836:19667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005581
VERSION     KCWK01005581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11836:19667"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71319.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          160 c          125 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga ggccagggag cgctcccagg
      241 ttattcctgt attactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaggtaac acagcgtttt tgctcatctc tggactccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01005582             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:10026:14053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005582
VERSION     KCWK01005582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10026:14053"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..268
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <230..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71320.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       271..305
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           65 a          106 c           93 g           79 t
ORIGIN      
        1 acatgggggg gctcccgggc agagtgtcac catctcttgt tctggaagca tctccagcat
       61 tggaagtagt gatgtatgtt ggtaccagca actcccagga acggccccca aactcctcat
      121 caattatagt gatcagcgac tctcaggggt ccctgaccga ttctctggct ctaagtctgg
      181 cacctcagcc tccctggcca tcactggtct ccgatctgag gatgaggctg attattactg
      241 tgcagcctgg gatagcagcc tgagcagtcc ggtattcggc ggagggaccc ggctgaccgt
      301 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005583             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:14627:20728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005583
VERSION     KCWK01005583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:14627:20728"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71321.1"
                     /translation="DYYCQSTDTSGNYIF"
     J_segment       389..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          105 a          134 c          122 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggaggaat
      181 actggcaaaa aaatatgctc agtggttgca gcagaagcca ggccaggccc ctgtgttggt
      241 aatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gttccagttc
      301 agggacaaca cttgccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca acagacacca gtggtaatta catcttcggt gctgggaccc ggctcaacgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005584             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:14431:13430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005584
VERSION     KCWK01005584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14431:13430"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71322.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          140 c          137 g          103 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagtcatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005585             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:20187:19681
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005585
VERSION     KCWK01005585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20187:19681"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71323.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           84 a          156 c          125 g          110 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gtattggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcaacact cagagacagc
      241 ccccacactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tactgttgtt catataggag tggaaacact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005586             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:9241:15762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005586
VERSION     KCWK01005586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9241:15762"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71324.1"
                     /translation="DYYCQVWDTTLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          149 c          129 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005587             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:24537:17343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005587
VERSION     KCWK01005587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:24537:17343"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71325.1"
                     /translation="DYYCQVWDISSEHVLF"
     J_segment       391..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           87 a          141 c          136 g           98 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacagcc tctgcggcct cctatgatct gactcagcca
      121 ccctcggtgt cggtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaggtgcag ttgtgaattg gtaccaccag aagccaccgc aggcccctgt actggtcatc
      241 tatgctgata gcgatcggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacacggcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acattagtag tgaacatgta ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005588             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:25659:4702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005588
VERSION     KCWK01005588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:25659:4702"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71326.1"
                     /translation="DYFCQVFGSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          162 c          124 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttggcag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005589             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:6087:13098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005589
VERSION     KCWK01005589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6087:13098"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71327.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           97 a          142 c          121 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaagaatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tccagatcat
      241 ctatgaggac agtaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 tttctcaaca gacaccagtg gtaatcgggt attcggcgga gggacccgtc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tcttttcccg
//
LOCUS       KCWK01005590             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15051:4867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005590
VERSION     KCWK01005590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15051:4867"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71328.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          155 c          127 g          110 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtctcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcaa gtcccaggaa
      241 cagctcccaa actcctcatc tattatagtg atcaacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc tcagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gaggggttac atcttcggtg
      421 ctgggacccg gctcgccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01005591             405 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:18434:7913
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005591
VERSION     KCWK01005591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 405)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18434:7913"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    22..367
                     /note="immunoglobulin light chain variable region"
     V_region        22..367
     V_segment       22..330
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <298..>339
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71329.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       331..367
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        368..>405
                     /gene="IGLC"
BASE COUNT           80 a          129 c          106 g           90 t
ORIGIN      
        1 acatgggcag gttccctctc ccagcctgtg ctgactcagc caccctccct gtctgcatcc
       61 ccgggagcat cggccagact cccctgcacc ctgagcagtg acctcagtgt tggtagtaaa
      121 aacatgtact ggtaccagca gaggccaggg agcgctccca ggttattcct gtattactac
      181 tccgactcag acaagcagct gggacctggg gtccccaatc gagtctctgg ctccaaggag
      241 acctcaggta acacagcgtt tttgctcatc tctggactcc agcctgagga cgaggccgat
      301 tattactgtc aggtgtatga cagtagtgct gtgttattcg gaggagggac ccgactgacc
      361 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005592             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:12176:7388
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005592
VERSION     KCWK01005592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12176:7388"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71330.1"
                     /translation="DYYCQTWDIGIWIF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           84 a          164 c          120 g          100 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtggccac
      181 tacagctaca ccatcgcatg gcatcagcag caacaaggga aggcccctcg gttcttgatg
      241 tggcttaaga gtgatggcag ccacaccaag ggggacgggg tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggacattggc atttggatat tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005593             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:20421:5223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005593
VERSION     KCWK01005593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20421:5223"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71331.1"
                     /translation="EYYCQTWDIGIWVF"
     J_segment       398..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          160 c          121 g          105 t
ORIGIN      
        1 acatggggga gcagagccct gaggagtctg caccatggcc tggaccccaa tcctcctcct
       61 cctcctcact ctcctccttc actgcacagg gtctctctcc cagcctgtgc tgactcagtc
      121 gccctctgcc tctgcctccc tgggagcctc ggtcaagctc acctgcactc tgagcagtgg
      181 gcactatagt tataccatcg catggcatca acaatatcaa gggaaggccc ctcggttctt
      241 gatgtggctt aaaagtgatg gcagccacac caagggggac gggatccctg atcgcttctc
      301 aggctccagc tccggggctg agcgctacct ctccatctcc aacctccagt ctgaggatga
      361 ggctgagtat tactgtcaga cctgggacat tggcatttgg gtattcggcg gagggacccg
      421 gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005594             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:18638:12039
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005594
VERSION     KCWK01005594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18638:12039"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71332.1"
                     /translation="DYYCAAWDDSLSSLFF"
     J_segment       409..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          154 c          123 g          112 t
ORIGIN      
        1 acatggggga gcttcagctg cgggtacaga aggcaggact caggataatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gccaccctca acgtctgggg ctcccgggca gagtgtcacc atctcttgct
      181 ctggaagcag ctccaacatt ggaagtaatt atgtatactg gtaccagcag ctcccaggaa
      241 cggcccccaa actcctcatc tattataata atcagcgacc ctcaggggtc cctgaccgat
      301 tctctggctc taagtctggc acttcagcct ccctggccat cactggtctc cgatctgagg
      361 atgaggctga ttattactgt gcagcatggg atgacagcct gagcagtttg ttcttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005595             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:7059:7445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005595
VERSION     KCWK01005595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7059:7445"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71333.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          156 c          127 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005596             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:22502:4956
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005596
VERSION     KCWK01005596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22502:4956"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71334.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          154 c          115 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta ataatgtgtc ctggtaccag cacctcccag gaacagctcc caaactcctc
      241 atctattata atgatcaacg aggctcaggt gtctctgacc gattctctgg ctccaagtct
      301 gccacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcgt gggatgatag cctgagcagt tacatcttcg ctgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005597             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14723:18093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005597
VERSION     KCWK01005597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14723:18093"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71335.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          162 c          122 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatcctcg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005598             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:17725:18588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005598
VERSION     KCWK01005598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17725:18588"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    27..357
                     /note="immunoglobulin light chain variable region"
     V_region        27..357
     V_segment       27..322
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <285..>329
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71336.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       324..357
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        358..>395
                     /gene="IGLC"
BASE COUNT           76 a          121 c          103 g           95 t
ORIGIN      
        1 acatgggggg cacaggatcc tgggttcagg ctgccccgac tcagcctccc tctgtgtccg
       61 ggtctcctgg acagtcggtc accatctcct gcactggaac cagcagtgat attgggtatt
      121 ataacgctgt gtcttggtac caacagcatc caggcaaagc ccccaaactc ataatttttg
      181 acgtcattaa gcggccctca ggggtctctg atcgcttctc tggctccaag tctggcgaca
      241 cggcctccct gaccatctct gggctccggg ctgaggatga ggctgattat tactgcagct
      301 catatgcagg cagaaataat tttttattcg gaggagggac ccggctgacc gtcctaggtc
      361 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005599             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:14144:6928
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005599
VERSION     KCWK01005599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:14144:6928"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71337.1"
                     /translation="DYYCSSYGGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          154 c          122 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatggagg cagcaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005600             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:19689:3250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005600
VERSION     KCWK01005600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19689:3250"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71338.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          162 c          119 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtaataaaaa catgtactgg taccaacaga agccagggag cgctcccagg
      241 ttattcctat actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaactaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtttgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcgtt cactctcttc
      481 ccg
//
LOCUS       KCWK01005601             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:21122:21560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005601
VERSION     KCWK01005601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21122:21560"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..433
                     /note="immunoglobulin light chain variable region"
     V_region        88..433
     V_segment       88..396
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71339.1"
                     /translation="DYYCAIGHSSGYIF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           91 a          157 c          118 g          105 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggctc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcatctcctg gagcatcagc cagtctcaca tgcaccttca gtggtggcat caatgttgct
      181 ggctaccaca cacactggta ccagcagaag ccagggagtc ctccccggta tcttctgaga
      241 tacaaatcag actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 agagatgctt cagcgaacac agggatttta cgcatctctg ggctccagtc tgaggatgag
      361 gctgactatt actgtgccat tgggcacagc agcggttaca tcttcggtgc tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01005602             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:18328:6367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005602
VERSION     KCWK01005602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18328:6367"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71340.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       410..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           87 a          153 c          133 g          112 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg gcagagggtt accatctcct
      181 gcactgggag cagctccaac atcggggcgg gtttttatgt gtcctggtac cagcagttcc
      241 ctgggacagt ccccaaactc ctcatctttg aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggttcct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgctcat catgggaaag cagcctgaat tgggtattcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005603             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:3327:7622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005603
VERSION     KCWK01005603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:3327:7622"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..434
                     /note="immunoglobulin light chain variable region"
     V_region        86..434
     V_segment       86..395
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71341.1"
                     /translation="VYYCAIGHSSGLYIF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          157 c          117 g          111 t
ORIGIN      
        1 acatgggggg aaagaggctg tgtccaccat ggcctggact cctctcctcc tcctgctcct
       61 ctctcactgc acaggttccc tctccaagcc tatgctgact cagccggcct ccctctcagc
      121 atctcctgga gcatcagcca gtctcacatg caccttcagc ggtggcatca atgttgctgt
      181 ctaccacgta cactggtacc agcagaagcc agggagtccc ccccggtatc ttctgaggta
      241 caaatcagac tcagataagg gccagggctc tggggtcccc agccgcttct ctggatccag
      301 taatgcttca gcgaacacag ggattttacg catttctggg ctccagtctg aggatgaggc
      361 tgtctattac tgtgccattg ggcacagcag cggtctttac atcttcggtg ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01005604             359 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:17631:8326
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005604
VERSION     KCWK01005604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 359)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 359)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17631:8326"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..321
                     /note="immunoglobulin light chain variable region"
     V_region        8..321
     V_segment       8..283
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <249..>293
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71342.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       287..321
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        322..>359
                     /gene="IGLC"
BASE COUNT           78 a          110 c           96 g           75 t
ORIGIN      
        1 acatgggatc cccgggagca tcggccagac tcccctgcac cctgagcact gacctcagtg
       61 ttggtggtaa aaacatgtac tggtaccagc agaagccagg aagcgctccc aggttattgc
      121 tgtattacca ctccgactca gacaagcagc tgggacctgg ggtccccaat cgagtctctg
      181 gctccaagga gacctcaagt aacacagcgt ttttgctcat ctctgggctc cagcctgagg
      241 acgaggccga ttattactgt caggtgtatg acagtagtgc caacacgtta ttcggaggag
      301 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005605             372 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:25172:11945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005605
VERSION     KCWK01005605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 372)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:25172:11945"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..334
                     /note="immunoglobulin light chain variable region"
     V_region        8..334
     V_segment       8..297
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <265..>306
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71343.1"
                     /translation="DYYCQVYDSNAVLF"
     J_segment       301..334
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        335..>372
                     /gene="IGLC"
BASE COUNT           78 a          120 c           94 g           80 t
ORIGIN      
        1 acatgggcac cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg
       61 agcagtgacc tcagtgttgg cagtaaaaac atgtactggt accagcagaa gccagggagc
      121 gctcccaggt tattcctcta ctactactcc gactcagaca accaactggg acctggggtc
      181 cccaatcgag tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct
      241 gggctccagc ctgaggacga ggccgattat tactgccagg tgtatgacag taatgctgtt
      301 ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      361 actctcttcc cg
//
LOCUS       KCWK01005606             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:19858:20863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005606
VERSION     KCWK01005606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19858:20863"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    131..455
                     /note="immunoglobulin light chain variable region"
     V_region        131..455
     V_segment       131..418
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <380..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71344.1"
                     /translation="DYYCQSVDSSGNHPLF"
     J_segment       421..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT          111 a          139 c          136 g          107 t
ORIGIN      
        1 acatggggga agagcggcct ggggagccca gctgtgctgt ggttctagga ggaagagctc
       61 tgggtgtctc accatgacct ggaccactgt tctgctcccc tttctcactc tcttcacagg
      121 ctctgaggcc tcctatgagc tgacacagcc accctcagtg tcagtgtccc caggacagac
      181 ggccaggatc acctgctctg gagaaatact ggcaaaaaaa tatgctcagt ggttccagca
      241 gaagccaggc caggcccctg tgttggtgat atataaagac agtgagaggc cctcagggat
      301 ccctgaacga ttctctagtt ccagttcagg gacaacagtt accttgacca tcagtggggc
      361 ccaggtagaa gatgaggctg actattactg tcaatcagta gacagcagtg gtaatcatcc
      421 gttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01005607             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:14772:14264
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005607
VERSION     KCWK01005607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14772:14264"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71345.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       391..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           90 a          138 c          139 g           95 t
ORIGIN      
        1 acatggggga ctttgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctttacaggc tctgcggcct cctatgaggt gactcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtaaaa gtgtgcagtg gtaccagcag acgccaccgc aggcccctgt actggtcatt
      241 tatggtgata gggaacggcc ctcagggatc cctgagcgat tctctggctc caactcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg atagcagtag taaatatgta ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005608             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:18765:9425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005608
VERSION     KCWK01005608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18765:9425"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71346.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           97 a          143 c          122 g           98 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaagaatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tccagatcat
      241 ctatgaggac agtaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccagggggag gatgaagctg actactactg
      361 tttctcaaca gacaccagtg gtaatcgggt attcggcgga gggacccgtc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005609             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:5054:5034
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005609
VERSION     KCWK01005609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:5054:5034"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..432
                     /note="immunoglobulin light chain variable region"
     V_region        96..432
     V_segment       96..389
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71347.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       395..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           94 a          153 c          117 g          106 t
ORIGIN      
        1 acatgggggc acaggaggca gcactcagga cagtctccag catggcctgg tctctccttc
       61 tcactctgct ggttcactgc acagggtcct gggcccagtc tgtgctgacg cagccgccct
      121 cagcatctgg ggcccccggg cagagggtca ccatctcctg cactgggagc agctccaaca
      181 tcggggcggg ttattatgta tcctggtacc agcagttccc aggaacagcc cccaaactcc
      241 tcatctatga aaataataaa cgaccctcag gggtttctga ccgattctct ggctccaagt
      301 ctggtacctc agcctccctg accatcactg gactccaatc tgaggatgag gctgattatt
      361 actgctcagc atgggatagc agcctgagta tcaattacat cttcggttct gggacccgtc
      421 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005610             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:26678:11828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005610
VERSION     KCWK01005610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:26678:11828"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71348.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          157 c          126 g          111 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagtc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005611             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:19727:20939
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005611
VERSION     KCWK01005611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19727:20939"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..289
                     /note="immunoglobulin light chain variable region"
     V_region        5..289
     V_segment       5..252
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71349.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       254..289
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           68 a          102 c           81 g           76 t
ORIGIN      
        1 acatgggcag tcactctcac ctgtgcttcc agcactggag cagtcaccag tggtcactct
       61 ccacactggt tccagcagaa acctggacaa gcccccaaga cactgattta taatacaaac
      121 tacagacact cctggactcc tgcccggttc tcaggctccc tccttggggg taaagctgcc
      181 ctgacactgt caggtgcgca gcctgaggat gaggctgagt attattgttt actgtactat
      241 agtggtgctc agctgttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      301 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005612             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:12856:8342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005612
VERSION     KCWK01005612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12856:8342"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..447
                     /note="immunoglobulin light chain variable region"
     V_region        114..447
     V_segment       114..410
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71350.1"
                     /translation="DYYCLEWHDSLSTGLF"
     J_segment       411..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           95 a          154 c          126 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactccac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca acatctgggg cccccgggca gagggtcacc atctcctgca
      181 ctgggaacag ccccaatatc ggggcgaatt attatgtatc gtggtaccag catttcccag
      241 gaacagcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagtctg
      361 aggatgaggc tgattattac tgcttagaat ggcatgatag cctgagtact ggcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005613             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:16978:16049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005613
VERSION     KCWK01005613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16978:16049"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71351.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          147 c          129 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctggggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtacact ggtaccagca caagccaccg caggcccctg ttctgctcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttgttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005614             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:15388:14560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005614
VERSION     KCWK01005614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15388:14560"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71352.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctgggggc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005615             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:19954:21237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005615
VERSION     KCWK01005615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19954:21237"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71353.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          150 c          116 g          107 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggcacc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005616             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:21538:18062
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005616
VERSION     KCWK01005616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21538:18062"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71354.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          159 c          113 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagca aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005617             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:9579:17828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005617
VERSION     KCWK01005617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9579:17828"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71355.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       410..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           84 a          163 c          123 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcactggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta cttctactcc gactcagaca agcagctggg acctggggtc cccgatcgcg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtc ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005618             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:19708:14958
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005618
VERSION     KCWK01005618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19708:14958"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71356.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       400..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           95 a          162 c          110 g          107 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcaactcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 gcctaccaca tacactggta ccagcagaag ccagggagtc ccccccggta tcttctgact
      241 tacaaatcag actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaaaatgctt caacgaacac aggcatttta cacatctctg ggctccagtc tgaggatgag
      361 gctgactatt tctgtgccat tggacacagc agcggtcctt acatcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005619             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:4783:13158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005619
VERSION     KCWK01005619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:4783:13158"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71357.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           84 a          164 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005620             415 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:12804:16794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005620
VERSION     KCWK01005620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 415)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12804:16794"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    29..377
                     /note="immunoglobulin light chain variable region"
     V_region        29..377
     V_segment       29..337
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>349
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71358.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       340..377
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>415
                     /gene="IGLC"
BASE COUNT           84 a          132 c          104 g           95 t
ORIGIN      
        1 acatgggcac tgcacaggtt ccctctccaa gcctatgttg actcagccgg cctccctctc
       61 agcgtctcct ggagcatcag ccagtctcac atgcaccttc agcggtggca tcaatgttgc
      121 tggctaccac atacactggt accaacagag gccagggagt cctccccggt ttcttctgag
      181 atacaaatca gactcagata atggccaggg ctctggagtc cccaggcgct tctctggatc
      241 caaacatgct tcagcgaaca cagggatttt acgcatctct gggctccagt ctgaggatga
      301 ggctgactat tactgtgcca ttgggcacag cagcggtgat tacatcttcg gtggtgggac
      361 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005621             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:13776:21935
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005621
VERSION     KCWK01005621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13776:21935"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71359.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          138 c          121 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggagcaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005622             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:15256:4568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005622
VERSION     KCWK01005622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15256:4568"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71360.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          143 c          133 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggttctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg aggagacaac
      181 attggaagtg aagttgtcaa ctggtaccag cagaggccac cgcaggcccc tgtgctgctc
      241 atctatgctg attatgaacg gccctcaggg atccctgacc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattat
      361 tgtcaggtgt gggacattta tattgaccat ccggtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005623             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:13352:3572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005623
VERSION     KCWK01005623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13352:3572"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71361.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       392..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>464
                     /gene="IGLC"
BASE COUNT           89 a          144 c          135 g           96 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag actctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaggtga agttgtgaac tggtaccagc agaagccacc gcaggcccct gtcctggtca
      241 tctatgctaa taacgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg gggcgttact agtgatcatc ccttattcgg aggagggacc cggctgaccg
      421 tccaaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005624             455 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:8387:8184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005624
VERSION     KCWK01005624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 455)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:8387:8184"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..417
                     /note="immunoglobulin light chain variable region"
     V_region        93..417
     V_segment       93..380
                     /gene="IGLV3-35"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <342..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71362.1"
                     /translation="DYYCGSWDNSDKHYIF"
     J_segment       381..417
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>455
                     /gene="IGLC"
BASE COUNT           94 a          139 c          118 g          104 t
ORIGIN      
        1 acatggggga agcagaactc tgggtcgtct ccaccatggc ctggacccct cccctgctca
       61 tcctcctcac tctctgcaca ggttccgtgg tttcctctgg gctgactcag gagcctgcat
      121 tgtctgtggc cttgggacaa acagtcagga tgacctgcca aggagacagc ctcaaaacct
      181 attacataag ctggtaccaa cagaagccag gccaggcccc tgtgctggtc atctttggta
      241 acaccaatag gccctcaggg atcccaggcc gattctctgg ctcctggtca ggaaactcag
      301 gttccttgac catcactggg gctcaggtgg aagatgaggc tgactattac tgtggctcct
      361 gggataacag tgataagcat tacatcttcg gtgatgggac ccggttcacc gtcctaggtc
      421 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005625             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:11912:9534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005625
VERSION     KCWK01005625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11912:9534"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..425
                     /note="immunoglobulin light chain variable region"
     V_region        103..425
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71363.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>465
                     /gene="IGLC"
BASE COUNT           86 a          147 c          136 g           96 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgtga cgtcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaacta aatatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
      241 atctatgctg ataccagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg ggtatgaggc tgactatttc
      361 tgtcaggttt gggacgatag tagtgatcat ccggtattcg gcggagggac ccggctgacc
      421 gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005626             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:11003:9409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005626
VERSION     KCWK01005626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11003:9409"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..403
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71364.1"
                     /translation="DYYCSSYEGTNSFIF"
     J_segment       404..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          159 c          122 g          107 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggaccc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcccgg acagtcggtc accatctcct gcacgggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac cagcagcacc caggcaaagc
      241 ccccaaactc atgatttatg atgtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgcagct catatgaagg caccaacagt ttcatcttcg gtgttgggac
      421 ccggctcacc gtactaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005627             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:10748:6011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005627
VERSION     KCWK01005627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10748:6011"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    39..384
                     /note="immunoglobulin light chain variable region"
     V_region        39..384
     V_segment       39..347
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <315..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71365.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       348..384
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>422
                     /gene="IGLC"
BASE COUNT           84 a          137 c          106 g           95 t
ORIGIN      
        1 acatggggct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
       61 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      121 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      181 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      241 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      301 ctgaggacga ggccgattat tactgtcagg tgtatgacga tagtgctgtg ttattcggag
      361 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      421 cg
//
LOCUS       KCWK01005628             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:14184:4973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005628
VERSION     KCWK01005628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14184:4973"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71366.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       412..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           94 a          155 c          126 g          112 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg agcagctcca acattggagg ttattatgtg cagtggtacc agcaacttcc
      241 aggaacggcc cccaaactcc tcatctatga aaatgataaa cgaccctcag gggtttctga
      301 tcgattctct ggctcccagt ctgatacctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agcttaagtg ttgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01005629             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12571:17503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005629
VERSION     KCWK01005629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12571:17503"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71367.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       398..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          159 c          127 g          100 t
ORIGIN      
        1 acatggggga gcagagccct gaggagtctg caccatggcc tggaccccaa tcctcctcct
       61 cctcctcact ctcctccttc actgcacagg gtctctctcc cagcctgtgc tgactcagtc
      121 gccctctgcc tctgcctccc tgggagcctc ggtcaagctc acctgcactc tgagcagtgg
      181 acacaggagc tacaccatcg cgtggcatca gcagcagcaa gggaaggccc ctcgatactt
      241 gatgtggctt aaaagtgatg gcagccacag caagggggac gggatccctg atcgcttctc
      301 aggctccagc tccggggctg agcgctacct caccatctcc aacctccagt ctgaggatga
      361 ggctgattat tattgtcaga cgtgggatat tggcatttgg gtgttcggcg gagggacccg
      421 gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005630             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18789:9896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005630
VERSION     KCWK01005630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18789:9896"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71368.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          129 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccacca caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005631             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:22089:7843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005631
VERSION     KCWK01005631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:22089:7843"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71369.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           84 a          149 c          136 g           93 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacagac tctgcggcct cccatgatct gactcagcca
      121 ccctcggtga ccgtgtcccc aggacagacg gccaggatca cctgcggggg agacaagatt
      181 cgaagtgaag ttgtgaactg gtaccagcag aagccagcgc aggcccctgt attggtcatc
      241 tttgctgata ccgaacggcc cgcagggatc cccgagcgat tctctggctc caaatcaggg
      301 aacacggcca ccctgaccat ccgcggggtc gaggccgggg atgaggctga cttttactgt
      361 caggtgtggg acattcgtag tgatcgtccg ctattcggcg gagggacccg gctcaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005632             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:20022:10044
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005632
VERSION     KCWK01005632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20022:10044"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71370.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           94 a          161 c          123 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg acgcagccac
      121 cctccctgtc tgcatccccg ggagcaccgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg cagtaaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tatttctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gatcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tatatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005633             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:17204:17837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005633
VERSION     KCWK01005633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17204:17837"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..388
                     /note="immunoglobulin light chain variable region"
     V_region        58..388
     V_segment       58..344
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <316..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71371.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       351..388
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           76 a          142 c          103 g          105 t
ORIGIN      
        1 acatgggggg ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcaa
       61 gctgccccga ctcagcctcc ctctgtgtcc gggtctcctg gacagtcggt caccttctcc
      121 tgcactggaa ccggcagtga ttttgggtct tataatgctg tgtcttggta ccaacagcat
      181 ccaggcaaag ccccccaact cataattttt gaggtcaata agcggccctc aggggtctct
      241 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag
      301 gctgaggatg aggctgatta ttactgctgc tcatatgtag gcagcaacac ttacatcttc
      361 gatgttggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      421 ttcccg
//
LOCUS       KCWK01005634             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:23045:12511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005634
VERSION     KCWK01005634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23045:12511"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..388
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71372.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       390..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          150 c          120 g          107 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag cacctccaac
      181 attggaggtt attatgtgca gtggtaccag cagcttccag gaacggcccc caaactcctc
      241 atctatgaaa atgataaacg accctcaggg gtttctgatc gattctctgg ctcccagtct
      301 gattcctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgccagtcct atgacagcag cttgagtgtt gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005635             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:8898:12112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005635
VERSION     KCWK01005635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8898:12112"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..397
                     /note="immunoglobulin light chain variable region"
     V_region        85..397
     V_segment       85..360
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>369
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71373.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       361..397
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        398..>435
                     /gene="IGLC"
BASE COUNT           81 a          139 c          112 g          103 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcct ggagcatcag ccagtctcac atgcaccttc
      121 agcggtggca tcaatgttgc tgtctaccac gtacactggt accagcagaa gccagggagt
      181 cccccccggt ttcttctgag gtacaaatca gactcagata agggccaggg ctctggagtc
      241 cccagccgct tctctggatc cagtaatgtt tcagcgaaca cagggatttt acgcatttct
      301 gggctccagt ctgaggatga ggctgactat tactgtgcca ttgggcacag cagcggtcct
      361 tacatcttcg gtgctgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg
      421 gtcactctgt tcccg
//
LOCUS       KCWK01005636             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:20548:18864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005636
VERSION     KCWK01005636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20548:18864"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71374.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          107 a          137 c          120 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtctgtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca acagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccagaca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005637             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:6920:2730
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005637
VERSION     KCWK01005637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6920:2730"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71375.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          156 c          119 g          107 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cggcggtggc atcaatgttg
      181 ctggctacca catacactgg taccaacaga agccagggag tcccccccgg tatcttctga
      241 ggtacaaatc agactcagat aagggccagg gctctggagt caccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtga ttacatcttc ggtgctggga
      421 cccgactcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005638             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:20036:6986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005638
VERSION     KCWK01005638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20036:6986"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71376.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           91 a          154 c          118 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcata atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctgga ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacgcttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005639             507 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:21563:14150
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005639
VERSION     KCWK01005639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 507)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 507)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..507
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21563:14150"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    139..469
                     /note="immunoglobulin light chain variable region"
     V_region        139..469
     V_segment       139..428
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <394..>441
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71377.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       432..469
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        470..>507
                     /gene="IGLC"
BASE COUNT          102 a          157 c          135 g          113 t
ORIGIN      
        1 acatggggga gagggagaga tttgggtgaa gcgcagcttc agctgtgggt acagaaggca
       61 ggactcagga caatctccag catggcctgg ttccctctcg tcctcaccct cctcactcac
      121 tgtgcagggt cctgggccca gtctgtgctg actcagcctc cctcagcgtc tgaggccgcc
      181 aggaagagtg tcaccatctc ctgttctgga agcagctcca acatcggaag taataatgtg
      241 tcctggtacc agcacctccc aggaacagct cccaaactcc tcatctatta taatgatcaa
      301 cgaggctcag gtgtctctga ccgattctct ggctccaagt ctggcacgtc agcctccctg
      361 gccatcagtg ggctccagac cgaggatgag gctgattatt actgcgcagc gtgggatgat
      421 agcctgagta gttacatctt cgctgctggg acccggctca ccgtcctagg tcagcccaag
      481 gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01005640             342 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:21782:4067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005640
VERSION     KCWK01005640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 342)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:21782:4067"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..304
                     /note="immunoglobulin light chain variable region"
     V_region        6..304
     V_segment       6..265
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <232..>276
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71378.1"
                     /translation="DYYCAMWHSSVYGLF"
     J_segment       267..304
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        305..>342
                     /gene="IGLC"
BASE COUNT           73 a           98 c           86 g           85 t
ORIGIN      
        1 atgggagcca gactcagctg caccttgagc agtggcatca atgttggtag ttacagcata
       61 ttctggtacc agcagaagcc agggagtcct ccccgattcc ttctgtacta ctactcagac
      121 tcaaataatc accagggctc tggagtcccc agccgcttct ctggatccaa agatacttca
      181 gccaatgcag ggcttttact gatctctggg ctccagtctg aagatgaggc tgactattac
      241 tgtgccatgt ggcacagtag tgtttatggc ttattcggag gagggacccg gctgaccgtc
      301 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005641             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:9456:18540
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005641
VERSION     KCWK01005641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:9456:18540"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71379.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           88 a          143 c          126 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgatgctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005642             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:21733:11103
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005642
VERSION     KCWK01005642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21733:11103"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71380.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          154 c          127 g          112 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaacatt ggaggttatt atgtgcagtg gtaccaacag cttccaggaa
      241 cggcccccaa actcctcatc tatgaaaatg ataaacgacc ctcaggggtt tctgatcgat
      301 tctctggctc ccagtctgat tcctcagcct ccctgaccgt cactggactc cagtctgagg
      361 atgaggctga ttattactgc cagtcctatg acagcagctt gagtgttgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005643             495 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:20409:6945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005643
VERSION     KCWK01005643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 495)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20409:6945"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..457
                     /note="immunoglobulin light chain variable region"
     V_region        109..457
     V_segment       109..419
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71381.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       423..457
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        458..>495
                     /gene="IGLC"
BASE COUNT           92 a          170 c          124 g          109 t
ORIGIN      
        1 acatgggggc ccaaccctgg gtctgtggcc tcagaggtag ccgtgtccac catggccctg
       61 actcctctcc tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg
      121 actcagcctc cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg
      181 agcactgacc tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc
      241 gctcccaggt tattgctgta ttaccactcc gactcagaca agcagctggg acctggggtc
      301 cccaatcgag tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct
      361 gggctccagc ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac
      421 acgttattcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      481 gtcactctct tcccg
//
LOCUS       KCWK01005644             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:11045:9931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005644
VERSION     KCWK01005644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11045:9931"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71382.1"
                     /translation="DYYCQVFDDSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          163 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg gaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tcttcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtccta cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacga tagtgctgta ttattcggag
      421 gcgggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005645             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:10700:10470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005645
VERSION     KCWK01005645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10700:10470"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71383.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          150 c          135 g           94 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca cagactctgc gacctcctat gacctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaac taaatatgtg cactggtacc agcagaagcc agcgcaggcc cctgtgttgg
      241 tcatctatgc tgataccaga cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cgggtatgag gctgactatt
      361 tctgtcaggt gtgggacgat agtagtgatc atccggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005646             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:20212:15030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005646
VERSION     KCWK01005646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20212:15030"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..441
                     /note="immunoglobulin light chain variable region"
     V_region        95..441
     V_segment       95..406
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71384.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>481
                     /gene="IGLC"
BASE COUNT           92 a          165 c          110 g          114 t
ORIGIN      
        1 acatggggcc actgcaggga aagaggctgt gtccaccatg gcctggactc ctctcctcct
       61 cctgctcctc tctcactgca caggttccct ctcccagcct gtgctgaccc agccaacctc
      121 cctctcagca tctccgggag catcagccag actcagctgc acctttagca gtggcatcaa
      181 tgttggtagt tacagcatat tctggtacca gcagaagcca gggagtcctc cccggtacct
      241 tctctactac tactcagact caagtaaaca ccagggctct ggagtcccca gccgcttctc
      301 tggatccaaa gatgcttcgg ccaatgcagg ccttttactg atctctgggc tccagtctga
      361 agatgaggct gactattact gtgccatatg gcacagcagc gcttcttact tcttcggtac
      421 tgggacccgg ctcaccgtcc tgggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01005647             330 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:19737:16479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005647
VERSION     KCWK01005647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 330)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 330)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..330
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19737:16479"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..292
                     /note="immunoglobulin light chain variable region"
     V_region        8..292
     V_segment       8..255
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>264
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71385.1"
                     /translation="DYYCQSYDSNLSAMLF"
     J_segment       257..292
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        293..>330
                     /gene="IGLC"
BASE COUNT           69 a           96 c           85 g           80 t
ORIGIN      
        1 acatgggggg tcaccatctc ctgcactggg agtagttcca acatcggggc gggttattat
       61 gtgcagtggt accagcaact tccaggagcg gcccccaaac tcctcatcta tgaaaacaat
      121 atgcgaccct caggggtttc agatcgattc tctggctcca agtctggtac ctcagcctcc
      181 ctgaccatca gtggactcca gtctgaggat gaggctgatt attactgcca gtcctatgac
      241 agtaatttga gtgctatgtt attcggagga gggacccggc tgaccgtcct aggtcagccc
      301 aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005648             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:12471:2986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005648
VERSION     KCWK01005648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12471:2986"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71386.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          147 c          132 g           96 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctttga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaatta aatttgtcca ctggtaccag cagaagccag cgcaggcccc tgtgaaggtc
      241 atctatgctg atgacaaacg gccctcaggg atccctgaga gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattcc
      361 tgtcaggtgt gggacagtga gactgattat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005649             319 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:10680:15837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005649
VERSION     KCWK01005649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 319)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 319)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:10680:15837"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..281
                     /note="immunoglobulin light chain variable region"
     V_region        8..281
     V_segment       8..242
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <209..>253
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71387.1"
                     /translation="DYYCAIGHSSGLYIF"
     J_segment       244..281
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        282..>319
                     /gene="IGLC"
BASE COUNT           64 a           95 c           86 g           74 t
ORIGIN      
        1 acatgggggt ggcatcaatg ttgctgtcta ccacgtacac tggtaccaac agaagccagg
       61 gagtcccccc cggtatcttc tgaggtacaa atcagactca gataagggcc agggctctgg
      121 ggtccccagc cgcttctctg gatccagtaa tgcttcagcg aacacaggga ttttacgcat
      181 ttctgggctc cagtctgagg atgaggctga ctattactgt gccattgggc acagcagcgg
      241 tctttacatc ttcggtgctg ggacccggct caccgtccta ggtcagccca aggcttcccc
      301 cacggtcact ctgttcccg
//
LOCUS       KCWK01005650             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:16111:8240
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005650
VERSION     KCWK01005650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16111:8240"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..396
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71388.1"
                     /translation="DYYCGIGHSSGNYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           95 a          155 c          117 g          107 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatcctga ctcagccggc ctccctctca
      121 gcatctcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 ggctaccaca tacactggta ccagcagaag ccagggagtc ctccccggta tcttctgaga
      241 tacaagtcag actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagcgaacac aggaatttta cgcatctctg ggctccagtc tgaggatgag
      361 gctgactatt actgtggcat tgggcacagc agcggtaatt acatattcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005651             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:18853:10701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005651
VERSION     KCWK01005651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18853:10701"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71389.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           91 a          147 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctcggcct cctatgatct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtcaaa gtgtgcactg gtaccagcac aagccaccgc aggcccctgt actggtcatc
      241 ttttattata ccgaacggcc ctcaggaatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acacaactat tgatcacggc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005652             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:21486:15678
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005652
VERSION     KCWK01005652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21486:15678"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71390.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          148 c          128 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtacact ggtaccagca caagccaccg caggcccctg ttctgctcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttgttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005653             311 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:16449:12962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005653
VERSION     KCWK01005653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 311)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 311)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..311
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16449:12962"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..266
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71391.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       269..306
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>311
                     /gene="IGLC"
BASE COUNT           71 a           92 c           80 g           68 t
ORIGIN      
        1 acatgggagc cagtctcaca tgcaccttca gcggtggcat caatgttgct gcctaccaca
       61 tacactggta ccagcagaag ccagggagtc ctccccggta tcttctgaga tacaaatcag
      121 actcagataa ggaccagggc tctggagtcc ccagccgctt ctctggatcc aaagatgcct
      181 cagcgaacac agggatttta cgcatctctg ggctccagtc tgaggatgag gctgactact
      241 actgtgccat tgggcacagc agcggtgatt acattttcgc tgctgggacc cgcctcaccg
      301 tcctaggtca g
//
LOCUS       KCWK01005654             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:9462:7480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005654
VERSION     KCWK01005654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9462:7480"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71392.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          141 c          132 g           96 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga attgactcag
      121 tcattctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005655             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:15576:8645
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005655
VERSION     KCWK01005655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15576:8645"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71393.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       403..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           83 a          162 c          128 g           98 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtggt gactcagtcg
      121 tcctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcggtggg
      181 cacagcgact acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggtatttg
      241 atgtggctta aaagtgatgg cagccacagc aaggggggcg ggatccctga tcgcttctcc
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggagact ggcattcagg tgttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005656             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:26877:15869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005656
VERSION     KCWK01005656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:26877:15869"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71394.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          162 c          111 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005657             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:15173:21155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005657
VERSION     KCWK01005657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15173:21155"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71395.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           88 a          144 c          126 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gcgatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005658             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:15286:9121
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005658
VERSION     KCWK01005658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:15286:9121"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..400
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71396.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           91 a          153 c          120 g          111 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctcctct
       61 cctcctcacc cttctcattc acttcacagt tccagggtcc tgggcccagt ctgtgctgac
      121 gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag
      181 cagctccaac attggagatt attttgtgca gtggtaccag caccttccag gaacggcccc
      241 caaactcctc atttatgaaa ataataagcg accctcaggc atttctgatc gattctctgg
      301 ctcccagtct ggaacctcag cctccctgac catcactgga ctccagtctg aggatgaggc
      361 tgattattac tgccagtcct atgacagcag tttgattgct gtgttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005659             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:21829:4237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005659
VERSION     KCWK01005659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21829:4237"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71397.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           89 a          153 c          127 g          111 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg aggttattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccaaac tcctcatcta tgaaaatgat aaacgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctgattc ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagcttga gtgttgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005660             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:12738:14998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005660
VERSION     KCWK01005660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12738:14998"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..435
                     /note="immunoglobulin light chain variable region"
     V_region        87..435
     V_segment       87..396
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71398.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       401..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           91 a          158 c          111 g          113 t
ORIGIN      
        1 acatgggagg gaaagaggct gtgtccacca tggcctggac tcctctcctc ctcctgctcc
       61 tctctcactg cacaggttcc ctctcccagc ctgtgctgac ccagccaacc tccctctcag
      121 catctccggg agcatcagtc agactcagct gcaccttgag cagtggcatc aatgttggtt
      181 cttacaccat attctggtac cagcagaagc cagggagtcc tccccggttc cttctgtact
      241 actactcaga ctcaaataat caccagggct ctggagtccc cagccgcttc tctggatcca
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccatg tggcacagca gcgcttatgc cttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005661             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:23749:16594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005661
VERSION     KCWK01005661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:23749:16594"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..324
                     /note="immunoglobulin light chain variable region"
     V_region        8..324
     V_segment       8..287
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <252..>296
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71399.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       290..324
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        325..>362
                     /gene="IGLC"
BASE COUNT           75 a          112 c           91 g           84 t
ORIGIN      
        1 acatgggagc atctccggga gcatcagcca gactcagctg caccttgagc agtggcatca
       61 gtgttggtac ttacagcata ttctggtacc agcagaagcc agggagtcct ccccggtacc
      121 ttctgtacta ccactcagac tcaagtaaac accagggctc tggagtcccc agccgcttct
      181 ctggatccaa agatgcttca gccaatgcag gtctgttact gatctctggg ctccagtctg
      241 aagatgaggc tgactattac tgtgccatat ggcacagcag cgcttcttgc atcttcggtg
      301 gtgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      361 cg
//
LOCUS       KCWK01005662             490 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:14141:18573
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005662
VERSION     KCWK01005662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 490)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14141:18573"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..452
                     /note="immunoglobulin light chain variable region"
     V_region        116..452
     V_segment       116..409
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>424
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71400.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       415..452
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>490
                     /gene="IGLC"
BASE COUNT           97 a          158 c          123 g          112 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctctccttc tcactctgct ggttcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagcatctgg ggcccccggg cagagggtca ccatctcctg
      181 cactgggagc agctccaaca tcggggcggg ttattatgta tcctggtacc agcagttccc
      241 aggaacagcc cccaaactcc tcatctatga aaataataaa cgaccctcag gggtttctga
      301 ccgattctct ggctccaagt ctggtacctc agcctccctg accatcactg gactccaatc
      361 tgaggatgag gctgattatt actgctcagc atgggatagc agcctgagta tcaattacat
      421 cttcggttct gggacccgtc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac
      481 tctgttcccg
//
LOCUS       KCWK01005663             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:19723:3558
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005663
VERSION     KCWK01005663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19723:3558"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71401.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          154 c          120 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccgg gaagagtgtc tccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctctcagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagcggt tacatcttcg gtgctgggac ccggctcgcc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005664             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:25033:18536
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005664
VERSION     KCWK01005664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:25033:18536"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..403
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71402.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       405..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           97 a          152 c          115 g          116 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcgcagcctg tgctgactca gccaacctcc
      121 ctctcagcat ctcctggagc atcagccaga ctcacctgca ccttgaacag tggcatcagt
      181 gttggtaatt acaggatatt ctggtaccac cagaagccag ggagtcctcc ccggtatctt
      241 ctgaactacc acacagactc agatattcat cagggggctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatgcaggg attttactca tctctggact ccagtctgag
      361 gatgaggctg actattactg tatgatttgg cacaacaatg cttattgggt tttcggcgga
      421 gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005665             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11856:15871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005665
VERSION     KCWK01005665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11856:15871"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71403.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           92 a          147 c          126 g           96 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtcaaag tgtgcactgg taccagcaca agccaccgca ggcccctata ctggtcatct
      241 tttattatac cgaacggccc tcaggaatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cacaactatt gatcacggct tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005666             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:13326:23112
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005666
VERSION     KCWK01005666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:13326:23112"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71404.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       390..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          137 c          138 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcaggc
      121 accctcgatt tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 gtatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatgaata gtcatcatct gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005667             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:15807:16474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005667
VERSION     KCWK01005667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15807:16474"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71405.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          156 c          120 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatgtt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacgcttta ttcttcggac gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005668             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:7219:14756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005668
VERSION     KCWK01005668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7219:14756"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71406.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          162 c          120 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatattgg caataaaaac atgtactggt accagcagaa gccagggagc gctcccaagt
      241 tattcctgta ctactactcc gactcagaca tgcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggggacc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005669             501 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17291:18321
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005669
VERSION     KCWK01005669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 501)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17291:18321"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    133..463
                     /note="immunoglobulin light chain variable region"
     V_region        133..463
     V_segment       133..426
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <388..>435
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71407.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       427..463
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        464..>501
                     /gene="IGLC"
BASE COUNT           99 a          160 c          132 g          110 t
ORIGIN      
        1 acatgggcaa cgcagagtac atgggggcag cttcagctgt gggtacagaa ggcaggactc
       61 aggacaatct ccagcatggc ctggttccct ctcgtcctca ccctcctcac tcactgtgca
      121 gggtcctggg cccagtctgt gctgactcag cctccctcag cgtctgaggc cgccaggaac
      181 agtgtcgcca tctcctgttc tggaagcagc tccaacatcg gaagtcatag tgtatcctgg
      241 taccagcagc tcccaggaac agctcccaaa ctcctcatct attatgatga tcaacgagcc
      301 tcaggtgtct ctgaccgatt ctctggctcc aggtctggca cgtcagcctc cctggccatc
      361 agtgggctcc agaccgagga tgaggctgat tattactgcg cagcatggga tgatagcctg
      421 agaggttaca tcttcggtga tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc
      481 cccacggtca ctctgttccc g
//
LOCUS       KCWK01005670             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:16624:10774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005670
VERSION     KCWK01005670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16624:10774"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71408.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          157 c          128 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtc cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaggca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacggg cctcaggtgt ctctggccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005671             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:22134:5450
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005671
VERSION     KCWK01005671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22134:5450"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71409.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          147 c          130 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtacact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgggcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttgttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005672             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:21608:21222
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005672
VERSION     KCWK01005672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21608:21222"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71410.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          162 c          110 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcacg ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggaaca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005673             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:10881:3801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005673
VERSION     KCWK01005673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10881:3801"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71411.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          155 c          127 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtaac catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcggcatgg gatgatagcc tgagaggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005674             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:23099:3418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005674
VERSION     KCWK01005674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23099:3418"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..411
                     /note="immunoglobulin light chain variable region"
     V_region        81..411
     V_segment       81..370
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71412.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       374..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           87 a          148 c          111 g          103 t
ORIGIN      
        1 acatggggag gacaatctcc agcatggcct ggttccctct cgtcctcacc ctcctcactc
       61 actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc tccctcagcg tctgaggccg
      121 ccaggaagag tgtcaccatc tcctgttctg gaagcagctc caacatcgga agtaataatg
      181 tgtcctggta ccagcacctc ccaggaacag ctcccaaact cctcatctat tataatgatc
      241 aacgaggctc aggtgtctct gaccgattct ctggctccaa gtctggcacg tcagcctccc
      301 tggccatcag tgggctccag accgaggatg aggctgatta ttactgcgca gcgtgggatg
      361 atagcctgag tagttacatc ttcgctgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005675             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:13966:5085
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005675
VERSION     KCWK01005675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13966:5085"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..403
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71413.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          154 c          116 g          116 t
ORIGIN      
        1 acatggggac tgcagtcgaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcgcagcctg tgctgactca gccaacctcc
      121 ctctcagctt ctcctggagc atcagccaga ctcacctgca ccttgagcag tggcatcagt
      181 gttggtactt acaggatatt ctggtaccag cagaggccag ggagtcctcc ccggtatctt
      241 ctgaaccacc acacagactc agataaacat cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatgcaggg attttgctca tctctgggct ccagtctgag
      361 gatgaggctg actattactg tatgatttgg cacaacaatg cttatgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005676             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:18290:14190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005676
VERSION     KCWK01005676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18290:14190"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..385
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71414.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       387..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           87 a          146 c          122 g          107 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgttgacgca gccgccctca
      121 gcatctgggg cccccgggca gagggtcacc atctcctgca ctgggagcag ctccaacatc
      181 ggggcgggtt tttatgtttc ctggtaccag cagttcccag gaacagcccc caaactcctc
      241 atctttgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggttcctcag cctccctgac catcactgga ctccaatctg aggatgaggc tgattattat
      361 tgttcatcat gggaaagcag cctgaattgg gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005677             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:16026:10335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005677
VERSION     KCWK01005677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:16026:10335"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71415.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          161 c          112 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcaactcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccaacaga agccagggag tcccccccgg tatcttctga
      241 gttacagatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaaaatgc ttcaacgaac acaggcattt tacacatctc tgggctccag tctgaggatg
      361 aggctgacta tttctgtgcc attggacaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005678             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:18413:6755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005678
VERSION     KCWK01005678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18413:6755"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71416.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           98 a          142 c          132 g           90 t
ORIGIN      
        1 acagggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga gctgactcag
      121 gcaccctcag tgtcagcggc ctcaggacag acggccagga tcacctgtgg cggagacaac
      181 attggaatta aaaatgtcca ctggtaccag cagaagccag cacaggcccc tgtggtagtc
      241 atctatgctg ataacaaacg gccctcaggg atccctgagc gactctctgg ctccaactca
      301 gggaatattg ccaccctgac catcagcagg gtcgaggccg gggatgaggc agactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg gtattcggcg gagggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005679             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:9090:17426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005679
VERSION     KCWK01005679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9090:17426"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71417.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           89 a          159 c          119 g          107 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcagc tgcaccttga gcagtggcgt caatgtgggt
      181 agttacagca tattctggta ccagcagaag ccagggagtc ctccccggta ccttctgtac
      241 taccagtcag actcaaggaa gcaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagccaatgc agggctgtta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccct atggcacagc agcgcttctt gcatcttcgg tggtgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005680             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:24341:15213
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005680
VERSION     KCWK01005680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24341:15213"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71418.1"
                     /translation="DYYCQVWDTTLDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          148 c          129 g           98 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaagccacc gcaggcccct gttctggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaact cttgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005681             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:7285:22800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005681
VERSION     KCWK01005681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:7285:22800"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71419.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           84 a          163 c          123 g          101 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggc
      181 cactacagct acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggttcttg
      241 atgtggctta agagtgatgg cagccacacc aagggggacg gggtcactga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatatt ggcatttggg tattcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005682             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:10678:15908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005682
VERSION     KCWK01005682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10678:15908"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71420.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          164 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005683             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:18609:10168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005683
VERSION     KCWK01005683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18609:10168"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71421.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           97 a          157 c          120 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc aacgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca actccaacat cggaagttat aatgtgtcct ggtaccagca actcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005684             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:9693:18140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005684
VERSION     KCWK01005684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9693:18140"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71422.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          161 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01005685             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:14709:14560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005685
VERSION     KCWK01005685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:14709:14560"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71423.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          161 c          124 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctgttcc
      481 cg
//
LOCUS       KCWK01005686             318 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:20858:7272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005686
VERSION     KCWK01005686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 318)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20858:7272"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..280
                     /note="immunoglobulin light chain variable region"
     V_region        8..280
     V_segment       8..243
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>252
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71424.1"
                     /translation="DYYCHVYDSSSNVLF"
     J_segment       244..280
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        281..>318
                     /gene="IGLC"
BASE COUNT           68 a           92 c           85 g           73 t
ORIGIN      
        1 acatggggtg acctcagtgt tggtggtaaa agcatgtact ggtaccagca gaagccaggg
       61 cgcgctccca ggtttttcct gtactacaac tccgactcag acaagcagct gggacctggg
      121 gtccccaatc gagtctctgg ctccaaggag acctcaagta acacagcctt tttgctcatc
      181 tccgggctcc agcctgagga cgaggccgat tattactgtc acgtatatga cagtagtagt
      241 aatgtgttat tcggaggagg gacccgtctg accgtcctag gtcagcccaa ggctgccccc
      301 tcggtcactc tcttcccg
//
LOCUS       KCWK01005687             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:17731:19743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005687
VERSION     KCWK01005687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17731:19743"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71425.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       390..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          144 c          133 g           91 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgaac tgactcagtc
      121 accctcagtg tcagcggcct caggacagcc ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa actgtgcact ggtaccagca gaagccaccg cagggccctg tattggtcat
      241 ctttgctgac agtaaacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatggat attcggcggg gggacccggc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005688             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:6108:11585
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005688
VERSION     KCWK01005688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6108:11585"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71426.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           83 a          163 c          123 g          102 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgt accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggc
      181 cactacagct acaccatcgc atggcatcag cagcagcaag ggaaggcccc tcggttcttg
      241 atgtggctta agagtgatgg cagccacacc aagggggacg gggtccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatatt ggcatttggg tattcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005689             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:14567:12116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005689
VERSION     KCWK01005689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:14567:12116"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71427.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          148 c          129 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacacca ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005690             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:25890:7190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005690
VERSION     KCWK01005690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:25890:7190"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71428.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           97 a          157 c          122 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctactataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctagcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagac tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005691             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:14070:5198
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005691
VERSION     KCWK01005691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14070:5198"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71429.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           94 a          136 c          117 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga cacattgcca aaaaaatatg
      181 cttattggtt ccagcggaag gcaggccagt cccctgtgct gatcatctat gaggacaaca
      241 aacggtcttc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gtagtggtaa tggcttattc ggaggaggga cccgactgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005692             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:16904:16630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005692
VERSION     KCWK01005692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16904:16630"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71430.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          109 a          136 c          120 g          101 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tctgtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa aaatatactc agtggttcca acagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005693             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:13174:11544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005693
VERSION     KCWK01005693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13174:11544"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..396
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71431.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       403..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           94 a          153 c          116 g          111 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcatctcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat cactgttgct
      181 ggctaccata tatattggta ccagcagaag ccagggagtc ccccccggta tcttctgagg
      241 tacaaatcag actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagcgaacac agggatttta cgcatatctg gactccagtc tgaggatgag
      361 gctgactatt actgtgccat tggacacagc agcggtgatt atatcttcgg tgctgggacc
      421 cgtctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005694             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:10727:5665
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005694
VERSION     KCWK01005694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:10727:5665"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71432.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           89 a          143 c          126 g          103 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc catcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacagc cggccaggat cacctgctct ggagatgtat
      181 tgccaaaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtattggtca
      241 tctctgagga caccgaacgg ccctctggga tccctgagag attctctggc tccagctcat
      301 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttactcagc agacagtagt ggtcatggct tcttcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005695             355 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:18667:6405
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005695
VERSION     KCWK01005695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 355)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18667:6405"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..317
                     /note="immunoglobulin light chain variable region"
     V_region        9..317
     V_segment       9..277
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <245..>289
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71433.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       281..317
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        318..>355
                     /gene="IGLC"
BASE COUNT           74 a          106 c           93 g           82 t
ORIGIN      
        1 acatggggct ggagcatcag ccagtctcac atgcaccttc agcggtggca tcaatgttgc
       61 tgactaccac gtacactggt atcagcggaa gccagggagt cccccccggt atcttctgag
      121 gtacaaatca gactcagata agggcctggg ctctggagtc cccagccgct tctctggatc
      181 caaagatgct tcagcgaata cagggatttt acacatctct ggtttccagt ctgaggatga
      241 ggctgactat tactgtgcca ttggccacgg tagcggtgac tacatcttcg gtactgggac
      301 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005696             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:12899:9870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005696
VERSION     KCWK01005696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12899:9870"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71434.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          156 c          126 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005697             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:20119:21381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005697
VERSION     KCWK01005697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20119:21381"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71435.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          151 c          116 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggcctc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005698             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:20245:6931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005698
VERSION     KCWK01005698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:20245:6931"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71436.1"
                     /translation="EYYCCSYTTRSIYVF"
     J_segment       404..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          154 c          118 g          114 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgcc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca gtggatccag
      181 cagtgacatt ggtaattcta actctgtctc ctggtaccag aagcatccag gcaaagcccc
      241 caaagtcatg atttatggtg tcagtaatcg ggcctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacgcgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgaatattac tgttgttcat atacaacccg tagtatttac gttttcggta ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01005699             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11571:14800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005699
VERSION     KCWK01005699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11571:14800"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71437.1"
                     /translation="DYFCQVWDSISDHPLF"
     J_segment       392..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          148 c          133 g           93 t
ORIGIN      
        1 acatggggtg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct cactgcacag cctctgcgac ctcctatgag ctgactcagc
      121 caccctcggt gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaactaa atatgtgcac tggtaccagc agaagccagc gcaggcccct gtgcaggtca
      241 tttatggtga taccaaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactatttct
      361 gtcaggtgtg ggacagtatt agtgatcatc ccttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005700             361 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:23008:4418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005700
VERSION     KCWK01005700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 361)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23008:4418"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..323
                     /note="immunoglobulin light chain variable region"
     V_region        9..323
     V_segment       9..286
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <254..>295
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71438.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       287..323
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        324..>361
                     /gene="IGLC"
BASE COUNT           76 a          110 c           96 g           79 t
ORIGIN      
        1 acatggggct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
       61 cagtgttggt aataaaaaca tgtactggta ccaacagaag ccagggagcg ctcccaggtt
      121 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      181 ctctggctcc aaggagacct caactaacac agcgtttttg ctcatctctg ggctccagcc
      241 tgaggacgag gccgattatt actgtcaggt gtttgacagt agtgctgtgt tgttcggagg
      301 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      361 g
//
LOCUS       KCWK01005701             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:19252:13307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005701
VERSION     KCWK01005701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19252:13307"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..450
                     /note="immunoglobulin light chain variable region"
     V_region        102..450
     V_segment       102..413
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71439.1"
                     /translation="DYYCHVYDSSSNVLF"
     J_segment       414..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           89 a          163 c          125 g          111 t
ORIGIN      
        1 acatggtggg ggggtctgtg gcctcagagg tagccgtgtc caccatggcc ctgactcctc
       61 tcctcctcct gctcctctct cactgcacag gttccctctc ccagcctgtg ctgactcagc
      121 caccctccct gtctgcatcc ccgggagcgt cggccagact cccctgcacc ctgagcagtg
      181 acctcagtgt tggtggtaaa aacatgtact ggtaccagca gaagccaggg cgcgctccca
      241 ggtttttcct gtactacaac tccgactcag acaagcagct gggacctggg gtccccaatc
      301 gagtctctgg ctccaaggag acctcaagta acacagcgtt tttgctcatc tccgggctcc
      361 agcctgagga cgaggccgat tattactgtc acgtatatga cagtagtagt aatgtgttat
      421 tcggaggagg gacccgtctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01005702             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:17500:21456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005702
VERSION     KCWK01005702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17500:21456"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..424
                     /note="immunoglobulin light chain variable region"
     V_region        106..424
     V_segment       106..392
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71440.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       393..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           91 a          142 c          128 g          101 t
ORIGIN      
        1 acatggggag ctgtgggctc agaagcagag ctctggggtg tctccaccat ggcctggact
       61 cctctctggc tcaccctcct cagtctttgc acaggttcta tggtttcttc tgagctgact
      121 caggaccctg cagtgtctgt ggccttgggg cagacagtca ggattacctg ccaaggagac
      181 agcctcagaa gttcttatgc aagctggtac caacagaggc caggccaggc ccctgtgctg
      241 gtcgtctatg gtaacaacta ccggccctca gggatcccag aacgattctc tggctcctac
      301 tcccgaaaca cagcttcctt gaccatcact ggggctcagg tggaagatga ggctgactat
      361 tactgtgact cctgggacag cagcggaacc caattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005703             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:6912:4003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005703
VERSION     KCWK01005703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6912:4003"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..392
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71441.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       406..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           91 a          153 c          121 g          109 t
ORIGIN      
        1 acatgggggt gggatctcag gaggcagcgc tctcaggact tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccccgact
      121 cagactccct ctgtgtccgg gtctcctgga cagtcggtca ccatctactg cactggaacc
      181 agcagtgata ttgggtatta tcatgctgtg tcttggtacc aacatcatcc aggcaaagcc
      241 cccaaactca tgatttatga ggtcaataaa cggcccgcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccagac tgaggatgag
      361 gctgactatt actgcagctc atatgcaggc agcaacagtt tattcttcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005704             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:20182:16584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005704
VERSION     KCWK01005704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20182:16584"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71442.1"
                     /translation="DYYCAVWDDRLTGYVF"
     J_segment       414..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          159 c          123 g          108 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcctcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagcaata gtgtttcctg gtaccaacag ctcccagaaa
      241 cggctcccaa actcctcatc tatcataatg atcggcgagc ctcaggtgtc cctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagtatggg atgatcgcct gaccggttac gtattcggtg
      421 ttgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01005705             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:18819:11418
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005705
VERSION     KCWK01005705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18819:11418"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71443.1"
                     /translation="DYFCQVWGSRSDHPVF"
     J_segment       391..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          147 c          138 g           92 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctatgagc tggctcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaac tatgtgcact ggtaccagca gaagccagcg caggcccctg tagagattat
      241 ctttgctgat aacaaacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gatcaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actatttctg
      361 tcaggtgtgg ggcagtcgta gtgatcatcc ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005706             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:23453:18020
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005706
VERSION     KCWK01005706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:23453:18020"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71444.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       397..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           90 a          159 c          121 g          101 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgtct ctgcctccct gggagcctcg gtcaaactca cctgtacttt gaacagtggg
      181 cacagcagct acaccatcgc atggcatcag cagcagcaag ggaaggcccc ccggtacttg
      241 atgtggctta aaagtgaagg cagccatagc aagggggacg ggatccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatact gacattgtgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005707             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:18657:3946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005707
VERSION     KCWK01005707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18657:3946"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71445.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          156 c          118 g          108 t
ORIGIN      
        1 acatgggggg gatctcacga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtcc ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005708             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:11737:6286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005708
VERSION     KCWK01005708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11737:6286"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71446.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          154 c          121 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca gcaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005709             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:7830:12614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005709
VERSION     KCWK01005709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7830:12614"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..389
                     /gene="IGLV3-35"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71447.1"
                     /translation="DYYCGSWDNSDKRYIF"
     J_segment       393..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          141 c          125 g          108 t
ORIGIN      
        1 acatggggag ctgtgggctc agaagcagaa ctctgggtcg tctccaccat ggcctggacc
       61 cctcccctgc tcatcctcct cactctctgc acaggttccg tggtttcctc tgggctgact
      121 caggagcctg cattgtctgt ggccttggga catacagtca ggatgacctg ccaaggagac
      181 agcctcaaaa cctattacgc aagctggtat caacagaagc caggccaggt ccctgtgctg
      241 gtcatctatg gtaacaccaa taggccctca gggatcccag gccgattctc tggctcctgg
      301 tcaggaaact caggttcctt gaccatcact ggggctcagg tggaagatga ggctgactat
      361 tactgtggct cctgggataa cagtgataag cgttacatct tcggtgatgg gacccggttc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01005710             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20444:16367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005710
VERSION     KCWK01005710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20444:16367"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..436
                     /note="immunoglobulin light chain variable region"
     V_region        103..436
     V_segment       103..399
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71448.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       401..436
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           96 a          149 c          117 g          112 t
ORIGIN      
        1 acatggggtc tggagccagg gatcccttcc aatatcagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcaatgactg tgcttccagc
      181 actggagcag tcaccagtgg tcactctcca cactggttcc agcagaaacc tggacaagcc
      241 cccaagacac tgatttataa tacaaactac agacactcct ggactcctgc ccggttctca
      301 ggctccctcc ttgggggtaa agctgccctg acactgtcag gtgcgcagcc tgaggatgag
      361 gctgagtatt attgtttact gtactatagt ggtgctcagc tgttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gtcccctcgg tcactctctt cccg
//
LOCUS       KCWK01005711             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:16347:20853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005711
VERSION     KCWK01005711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:16347:20853"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..393
                     /note="immunoglobulin light chain variable region"
     V_region        63..393
     V_segment       63..356
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <318..>365
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71449.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       357..393
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        394..>431
                     /gene="IGLC"
BASE COUNT           81 a          143 c          108 g           99 t
ORIGIN      
        1 acatgggggc ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg
       61 cccagtctgt gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca
      121 tctcctgttc tggaagcagc tccaacatcg gaagtaataa tgtgtcctgg taccagcacc
      181 tcccaggaac agctcccaaa ctcctcatct attataatga tcaacgaggc tcaggtgtct
      241 ctgaccgatt ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc
      301 agaccgagga tgaggctgat tattactgcg cagcgtggga tgataggctg agcagttaca
      361 tcttcgctgc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      421 ctctgttccc g
//
LOCUS       KCWK01005712             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:21104:18849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005712
VERSION     KCWK01005712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21104:18849"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71450.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          150 c          117 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctgggca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005713             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:14069:13860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005713
VERSION     KCWK01005713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14069:13860"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71451.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          154 c          119 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca gtggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcgtccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaagc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcggac gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005714             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:8448:13056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005714
VERSION     KCWK01005714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:8448:13056"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71452.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          142 c          133 g           96 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca caggctctgc gacctcctat gaattgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc aacagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgatagtaga cggccctcag ggatccctga gcgattctct ggctccaatt
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005715             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:25832:14380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005715
VERSION     KCWK01005715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:25832:14380"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71453.1"
                     /translation="HYYCMIWHNNAYWVF"
     J_segment       401..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          155 c          110 g          116 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcttctcc tggagcatca gccagactca cctgcacctt gaacagtggc atcagtgttg
      181 ctaattacag gatattctgg taccaccaga agccagggag tcctccccgg tatcttctga
      241 actaccacac agactcagat attcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcagggattt tactcatctc tggactccag tctgaggatg
      361 aggctcacta ttactgtatg atttggcaca acaatgctta ttgggttttc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005716             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:4685:18628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005716
VERSION     KCWK01005716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4685:18628"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71454.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          150 c          115 g          109 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgtgg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005717             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:16825:10045
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005717
VERSION     KCWK01005717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16825:10045"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71455.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          153 c          116 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta ataatgtgtc ctggtaccag cacctcccag gaacagctcc caaactcctc
      241 atctattata atgatcaacg aggctcaggc gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc cattagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcgt gggatgatag cctgagcagt tacatcttcg ctgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005718             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:23640:14552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005718
VERSION     KCWK01005718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23640:14552"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71456.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          162 c          116 g          108 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctctgcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcagactca gataaggacc agggctctgg agtccccggc cgcttctctg
      301 gatccaaaga tgcctcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctactactgt gccattgggc acagcagcgg tgattacatc ttcgctgctg
      421 ggacccgcct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005719             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:24361:13138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005719
VERSION     KCWK01005719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:24361:13138"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71457.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           88 a          143 c          127 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggaggg gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005720             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:17709:10787
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005720
VERSION     KCWK01005720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17709:10787"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71458.1"
                     /translation="DYYCQSGDSSGNHWVF"
     J_segment       392..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          103 a          130 c          132 g          101 t
ORIGIN      
        1 acatgggggg tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 ggcacccgca gtgtcagtgt ccccaggaca gacggccagg atcacctggt ctggagaaat
      181 actggcaata aaagatagtc agtggttcct gcagaagcca ggccaggccc ctctgatggc
      241 tatatatgaa gactctgaga ggccctcagg gattcctgag agattctcta gttccagttc
      301 agggccaaca gttacctcga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca ggagacagca gtggtaatca ttgggtattc ggcggaggga cccggctaag
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005721             451 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:19869:14661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005721
VERSION     KCWK01005721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 451)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19869:14661"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..413
                     /note="immunoglobulin light chain variable region"
     V_region        83..413
     V_segment       83..374
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71459.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       376..413
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>451
                     /gene="IGLC"
BASE COUNT           84 a          145 c          118 g          104 t
ORIGIN      
        1 acatggggca ctcaggacag tctccagcat ggcctggtct ctccttctca ctctgctggt
       61 tcactgcaca gggtcctggg cccagtctgt gctgacgcag ccgccctcag catctggggc
      121 ccccgggcag agggtcacca tctcctgcac tgggagcagc tccaacatcg gggcgggttt
      181 ttatgtatcc tggtaccagc agttcccagg aaaagccccc aagctcctca tctttgaaaa
      241 taacaagcga ccctcagggg tttctgaccg attctctggc tccaagtctg gttcctcagc
      301 ctccctgacc atcactggac tccaatctga ggatgaggct gattattatt gttcatcatg
      361 ggaaagcagc ctgaattggg tattcggcgg agggacccgg ctgaccgtcc taggtcagcc
      421 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005722             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:12941:11728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005722
VERSION     KCWK01005722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12941:11728"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71460.1"
                     /translation="DYYCSAWDSSLTGGLF"
     J_segment       406..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          155 c          124 g          106 t
ORIGIN      
        1 acatggggag cttcagctgt ggctagagaa gacaggactc aggacaatct ccagcatggc
       61 ctgcttccct ctcatcctca ccgtcctcac tcactgtgca ggatcctggg cccagtctgt
      121 gctgactcaa ccaccctcag cgtctggggc ccccgggcag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaatta tgtatactgg taccagcagt tctcagggaa
      241 ggcccccaaa ctcctcatcc ataataataa tcagcgaccc tcaggggtcc ctgatcgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agtccgagga
      361 tgaggctgat tattactgct cagcgtggga tagcagtctg accggtggct tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01005723             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:4486:8816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005723
VERSION     KCWK01005723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:4486:8816"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71461.1"
                     /translation="DYYCSSWGASLNWIF"
     J_segment       406..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           89 a          154 c          126 g          112 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct ctccttctca ctctgctggt tcactgcaca gggtcctggg cccagtctgt
      121 gctgacacag ccgccctcag tatctggggc ccccgggcag agggtcacca tctcctgcac
      181 tgggagcagc tccaacatcg gggcgggttt ttatgtatcc tggtaccagc agttcccagg
      241 aacagccccc aaactcctca tctttgaaaa tactaagcga ccctcagggg tttctgaccg
      301 attctctggc tccaagtctg attcctcagc ctccctgacc atcactggac tccaatctga
      361 ggatgaggct gattattatt gttcatcatg gggagccagc ctgaattgga tattcggcgg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01005724             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13672:12653
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005724
VERSION     KCWK01005724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13672:12653"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71462.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           96 a          156 c          123 g          107 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata atgtgtcctg gtaccagcac ctcccaggaa
      241 cagctcccaa actcctcatc tactataatg atcaacgagg ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcgtggg atgatagact gagcagttac atcttcgctg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01005725             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:10720:15056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005725
VERSION     KCWK01005725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10720:15056"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71463.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          109 a          136 c          120 g           98 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgacc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatactcagt ggttccagca gaagccaggc cagggcccta cactggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacagtt accttgacca tcagcggggc ccagacagaa gatgaggctg actattactg
      361 tcaatcagca gacagaagtc ctaatcatgt gtttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005726             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:26053:12945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005726
VERSION     KCWK01005726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:26053:12945"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..390
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71464.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       392..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          150 c          122 g          107 t
ORIGIN      
        1 acatgggggc acaggaggca gcactcagga cagtctccag catggcctgg tctcctctcc
       61 tcctcaccct tctcattcac tgcacagggt cctgggccca gtctgtgctg acgcagccgc
      121 cctcagtgtc tggggcgccc gggcagaggg tcaccatctc ctgcactggg agcagctcca
      181 acattggagg ttattatgtg cagtggtacc agcagcttcc aggaacggcc cccaaactcc
      241 tcatctatga aaatgataaa cgaccctcag gggtttctga tcgattctct ggctcccagt
      301 ctgattcctc agcctccctg accatcactg gactccagtc tgaggatgag gctgattatt
      361 actgccagtc ctatgacagc agcttgagtg ttgtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005727             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:13158:17119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005727
VERSION     KCWK01005727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:13158:17119"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71465.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          136 c          121 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctta ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtctgtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca acagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005728             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15841:8544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005728
VERSION     KCWK01005728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15841:8544"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71466.1"
                     /translation="DYYCASWDDTLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          159 c          118 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtactgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcatcatgg gatgataccc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005729             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:14997:17052
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005729
VERSION     KCWK01005729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14997:17052"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71467.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          161 c          124 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtc ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagag gccagggagc gctcccaggt
      241 tattcctgta ttactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaggtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005730             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:22600:8219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005730
VERSION     KCWK01005730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22600:8219"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71468.1"
                     /translation="DYHCQVFDSRDVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          159 c          122 g          113 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcatcctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactattcc gactcagaca aggaggtggg acctggggtc cccaatcgag
      301 tctctgtctc caaggaaacc tcatctaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat cactgtcagg tgtttgacag tcgtgatgtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005731             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:12159:15122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005731
VERSION     KCWK01005731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12159:15122"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71469.1"
                     /translation="DYYCSSYADRNNFLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          150 c          121 g          113 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gttcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatgtt gggtattata acgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 caaactcatg atttatgacg tcattaagcg gccctcaggg gtttctgatc gcttctctgg
      301 ctccaagtct ggcgacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcagacag aaataatttt ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005732             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:14306:9611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005732
VERSION     KCWK01005732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14306:9611"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..435
                     /note="immunoglobulin light chain variable region"
     V_region        92..435
     V_segment       92..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71470.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          161 c          111 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc tgcctgtgct gacccatcca acctccctct
      121 cagcatctcc gggagcatcg gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttcct
      241 tctactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt gctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005733             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:25452:9644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005733
VERSION     KCWK01005733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:25452:9644"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..419
                     /note="immunoglobulin light chain variable region"
     V_region        86..419
     V_segment       86..382
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71471.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       383..419
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           86 a          155 c          116 g          100 t
ORIGIN      
        1 acatggggga gtctgcacca tggcctggac cccaatcctc ctcctcctcc tcactctcct
       61 ccttcactgc acagggtctc tctcccagcc tgtgctgact cagtcgccct ctgtctctgc
      121 ctccctggga gcctcggtca aactcacctg tactttgaac agtgggcaca gcagctacac
      181 catcgcatgg catcagcagc agcaagggaa ggccccccgg tacttgatgt ggcttaaaag
      241 tgaaggcagc catagcaagg gggacgggat ccctgatcgc ttctcaggct ccagctccgg
      301 ggctgagcgc tacctcacca tctccaacct ccagtctgag gatgaggctg attattactg
      361 tcagacctgg gatactgaca ttgtgttatt cggaggaggg acccggctga ccgtcctagg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005734             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:18414:7310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005734
VERSION     KCWK01005734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18414:7310"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71472.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       402..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           86 a          157 c          126 g          107 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggcggttat aactatgtct cctggtacca acaacatcca gacacagccc
      241 ccaaactcat gatttatgag gtcagtaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgctgctca catgcaggca gtgatatttt cgtgttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005735             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:19263:15736
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005735
VERSION     KCWK01005735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19263:15736"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..279
                     /note="immunoglobulin light chain variable region"
     V_region        8..279
     V_segment       8..243
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71473.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       247..279
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>317
                     /gene="IGLC"
BASE COUNT           70 a           90 c           95 g           62 t
ORIGIN      
        1 acatgggggc caggatcacc tgtgggggag acaacattgg aactaaaact gtgcactggt
       61 accagcagaa gccaccgcag ggccctgtat tggtcatctt tgctgatagt aaacggccct
      121 cagggatccc tgagcgattc tctggctcca actcagggaa caccgccacc ctgaccatca
      181 gcagggtcga ggccggggat gaggctgact attactgtca ggtgtgggac agtagtagta
      241 aatggatatt cggcgggggg acccggctaa ccgtcctagg tcagcccaag gctgccccct
      301 cggtcactct cttcccg
//
LOCUS       KCWK01005736             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:8134:11540
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005736
VERSION     KCWK01005736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:8134:11540"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71474.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           96 a          158 c          116 g          110 t
ORIGIN      
        1 acatggggca ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggaac atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctggct accacataca ctggtaccaa caaaagccag ggagtcctcc ccggtatctt
      241 ctgagataca aatcagactc agataggggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc gaacacaggg attttacgca tctctggtct ccagtctgag
      361 gatgaggctg actattactg tgccattggg cacagcagcg gtgattacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005737             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16282:11173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005737
VERSION     KCWK01005737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16282:11173"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71475.1"
                     /translation="DYYCQSADTSGNHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          108 a          137 c          121 g          100 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg aactgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc agtggttcca gcagaagcca ggccaggccc ctatactggt
      241 aatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gtttccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacacca gtggtaatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005738             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:11442:4260
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005738
VERSION     KCWK01005738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:11442:4260"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..269
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71476.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       270..306
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           72 a          107 c           81 g           84 t
ORIGIN      
        1 acatgggagc cagactcagc tgcaccttta gcagtggcat caatgttggt agttacagca
       61 tattctggta ccagcagaag ccagggagtc ctccccggta ccttctctac tactactcag
      121 actcaagtaa acaccagggc tctggagtcc ccagccgctt ctctggatcc aaagatgctt
      181 cggccaatgc aggcctttta ctgatctctg ggctccagtc tgaagatgag gctgactatt
      241 actgtgccat atggcacagc agcgcttctt acttcttcgg tactgggacc cggctcaccg
      301 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005739             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:21184:6104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005739
VERSION     KCWK01005739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:21184:6104"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..396
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71477.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       397..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           90 a          152 c          119 g          110 t
ORIGIN      
        1 acatggggtc aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactt cacagttcca gggtcctggg cccagtctgt gctgacgcag
      121 ccgccctcag tgtctggggc gcccgggcag agggtcacca tctcctgcac tgggagcagc
      181 tccaacattg gagattattt tgtgcagtgg taccagcacc ttccaggaac ggcccccaaa
      241 ctcctcatct atgaaaataa taagcgaccc tcagggattt ctgatcgatt ctctggctcc
      301 cagtctggaa cctcagcctc cctgaccatc actggactcc agtctgagga tgaggctgat
      361 tattactgcc agtcctatga cagcagtttg attgctgtgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca cgctcttccc g
//
LOCUS       KCWK01005740             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:23779:8502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005740
VERSION     KCWK01005740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23779:8502"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..400
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71478.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       409..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           92 a          153 c          123 g          109 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagtatc tggggccccc ggacagaggg tcaccatctc ctgcattagc
      181 agcagctcca acatcggggc ggcttattat gtatcctggt accaacagtt cccaggaaca
      241 gcccccaaac tcctcatctt tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggtcc ctcagcctcc ctgaccatca ctggactcca atctgaggat
      361 gagggtgatt attactgttt agcatgggat accagcctga attggatctt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005741             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:15304:5060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005741
VERSION     KCWK01005741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15304:5060"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..426
                     /note="immunoglobulin light chain variable region"
     V_region        96..426
     V_segment       96..387
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71479.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       396..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          151 c          117 g          105 t
ORIGIN      
        1 acatgggggc acaggaggca gcactcagga cagtctccag catggcctgg tctctccttc
       61 tcactctgct ggttcactgc acagggtcct gggcccagtc tgtgctgacg cagccgccct
      121 cagcatctgg ggcccccgga cagagggtca ccatttcctg cattagcagc agctccaaca
      181 tcggggcggc ttattatgta tcctggtacc aacagttccc aggaacagcc cccaaactcc
      241 tcatctttga aaataataag cgaccctcag gggtttctga ccgattctct ggctccaagt
      301 ctggtccctc agcctccctg accatcactg gactccaatc tgaggatgag gctgattatt
      361 actgtttagc atgggatacc agcctgaatt ggatcttcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005742             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:9992:2735
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005742
VERSION     KCWK01005742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9992:2735"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71480.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           83 a          162 c          123 g          100 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgctgac tcagtcgccc
      121 tctgcctctg cctccctggg agcctcggtc aagctcacct gcactctgag cagtggccac
      181 tacagctaca ccatcgcatg gcatcagcag cagcaaggga aggcccctcg gttcttgatg
      241 tggcttaaga gtgatggcag ccacaccaag ggggacgggg tccctgatcg cttctcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatattggc atttgggtat tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005743             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:19741:3041
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005743
VERSION     KCWK01005743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19741:3041"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..403
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71481.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           86 a          163 c          120 g          111 t
ORIGIN      
        1 acatgggggt ctgtggcctc agaggtagcc gtgtccacca tggccctgac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac tcagccaccc
      121 tccctgtctg catccccggg agcatcggcc agactcccct gcaccctgag cagtgacctc
      181 agtgttggta gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta
      241 ttcctgtact actactccga ctcagacaac cagctgggac ctggggtccc caatcgagtc
      301 tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct
      361 gaggacgagg ccgattattt ctgccaggtg tttgacagta gtgttgtgtt cttcggagga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005744             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10778:17998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005744
VERSION     KCWK01005744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10778:17998"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71482.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           86 a          159 c          126 g          100 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtgga
      181 cacaggagct acaccatcgc gtggcatcag cagcagcaag ggaaggcccc tcgatacttg
      241 atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt attgtcagac gtgggatatt ggcatttggg tgttcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005745             410 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:23635:7699
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005745
VERSION     KCWK01005745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 410)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23635:7699"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    24..372
                     /note="immunoglobulin light chain variable region"
     V_region        24..372
     V_segment       24..333
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <300..>344
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71483.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       335..372
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        373..>410
                     /gene="IGLC"
BASE COUNT           86 a          129 c           95 g          100 t
ORIGIN      
        1 acatgggcac aggttccctc tcgcagcctg tgctgactca gccaacctcc ctctcagctt
       61 ctcctggagc atcagccaga ctcacctgca ccttgaacag tggcatcagt gttgctaatt
      121 acaggatatt ctggtaccac cagaagccag ggagtcctcc ccggtatctt ctgaactacc
      181 acacagactc agatattcac cagggctctg gagtccccag ccgcttctct ggatccaaag
      241 atgcttcggc caatgcaggg attttactca tctctggact ccagtctgag gatgaggctg
      301 actattactg tatgatttgg cacaacaatg cttattgggt tttcggcgga gggacccggc
      361 taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005746             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:16557:9430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005746
VERSION     KCWK01005746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16557:9430"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71484.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       413..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           91 a          156 c          128 g          113 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccctct
      181 cctgcactgg gagcagctcc aacattggag attattatgt gcagtggtac cagcagcttc
      241 caggaacggc ccccaaactc ctcatctatg aaaataataa gcgaccctca ggggtttctg
      301 atcgattctc tggctcccag tctggtacct cagcctccct gaccatcact ggactccagt
      361 ctgacgatga ggctgattat tactgtcagt cctatgatag cagcctgagt gttgtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01005747             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:17450:14226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005747
VERSION     KCWK01005747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17450:14226"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71485.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       401..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           87 a          158 c          123 g          106 t
ORIGIN      
        1 acatggggct ggggtctcag gaggcagcgc tctcgggaca tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagcctcgct cagtgtctgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgaca tcggtggtta taactatgtc tcctggtacc aacagcatcc aggcacagcc
      241 cccaaagtca tgatttatga ggtcagtaag cggccctcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccaggc tgaggacgag
      361 gctgattatt actgcagctc atatacaggc atcaacagtt acatcttcgg tggtgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005748             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:9414:15141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005748
VERSION     KCWK01005748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:9414:15141"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71486.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          163 c          109 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctctgactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005749             329 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:8444:9764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005749
VERSION     KCWK01005749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 329)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8444:9764"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..291
                     /note="immunoglobulin light chain variable region"
     V_region        7..291
     V_segment       7..254
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71487.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       255..291
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>329
                     /gene="IGLC"
BASE COUNT           69 a          103 c           82 g           75 t
ORIGIN      
        1 acatggggaa gagtgtcacc atctcctgtt ctggaagcag ctccaacatc ggaagtaatg
       61 tgtcctggta ccagcacctc ccaggaacag ctcccaaact cctcatctat tataatgatc
      121 aacgaggctc aggtgtctct gaccgattct ctggctccaa gtctggcacg tcagcctccc
      181 tggccatcag tgggctccag accgaggatg aggctgatta ttactgcgca gcgtgggatg
      241 atagcctgag cagttacatc ttcgctgctg ggacccggct caccgtccta ggtcagccca
      301 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005750             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:19595:2772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005750
VERSION     KCWK01005750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19595:2772"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71488.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          155 c          126 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agactccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagaaat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagcgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gttgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005751             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:22490:10092
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005751
VERSION     KCWK01005751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22490:10092"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..416
                     /note="immunoglobulin light chain variable region"
     V_region        83..416
     V_segment       83..379
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71489.1"
                     /translation="DYYCLEWHDSLSTGLF"
     J_segment       380..416
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           90 a          146 c          114 g          104 t
ORIGIN      
        1 acatggggca ctcaggacag tctccagcat ggcctggtct ctccttctca ctctgctggt
       61 tcactccaca gggtcctggg cccagtctgt gctgacgcag ccgccctcaa catctggggc
      121 ccccgggcag agggtcacca tctcctgcac tgggaacagc cccaatatcg gggcgaatta
      181 ttatgtatcg tggtaccagc atttcccagg aacagccccc aaactcctca tctatgaaaa
      241 taataagcga ccctcagggg tttctgaccg attctctggc tccaagtctg gtacctcagc
      301 ctccctgacc atcactgggc tccagtctga ggatgaggct gattattact gcttagaatg
      361 gcatgatagc ctgagtactg gcttattcgg aggagggacc cggctgaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005752             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:19876:8841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005752
VERSION     KCWK01005752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19876:8841"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71490.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       402..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          151 c          122 g          113 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggttcaggct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat aacgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 ccaaactcat aatttttgac gtcattaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcgacacg gcctccctga ccatctctgg gctccgggct gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gaaataattt tttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005753             349 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:5353:16895
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005753
VERSION     KCWK01005753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 349)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5353:16895"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..311
                     /note="immunoglobulin light chain variable region"
     V_region        4..311
     V_segment       4..272
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <239..>283
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71491.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       274..311
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        312..>349
                     /gene="IGLC"
BASE COUNT           75 a          101 c           90 g           83 t
ORIGIN      
        1 acatggggca tcagccagac tcacctgcac cttgagcagt ggcatcagtg ttggtactta
       61 caggatattc tggtaccagc agaggccagg gagtcctccc cggtatcttc tgaaccacca
      121 cacagactca gataaacatc agggctctgg agtccccagc cgcttctctg gatccaaaga
      181 tgcttcggcc aatgcaggga ttttgctcat ctctgggctc cagtctgagg atgaggctga
      241 ctattactgt atgatttggc acaacaatgc ttatgtgtta ttcggaggag ggacccggct
      301 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005754             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:15019:11127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005754
VERSION     KCWK01005754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15019:11127"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71492.1"
                     /translation="DYYCAAWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          157 c          122 g          112 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtttcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgctgcatgg gatgatagcc tgaccggtta catattcggt
      421 tttgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005755             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:21256:4184
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005755
VERSION     KCWK01005755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21256:4184"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71493.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           93 a          156 c          123 g          114 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cacttcacag ttccagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct gggacgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggagat tattttgtgc agtggtacca gcaccttcca
      241 ggaacggccc ccaaactcct catctatgaa aataataagc gaccctcagg gatttctgat
      301 cgattctctg gctcccagtc tggaacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gtttgattgc tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01005756             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18062:11468
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005756
VERSION     KCWK01005756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18062:11468"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71494.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          105 a          136 c          121 g          101 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tctgtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatactcagt ggttccagca gcagccaggc caggcccctt tcctggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacaatt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagta gacagcagtg gaaatcttcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005757             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:15108:20420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005757
VERSION     KCWK01005757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15108:20420"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..385
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71495.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       394..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           92 a          150 c          116 g          104 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gcatctgggg cccccggaca gagggtcacc atctcctgca ttagcagcag ctccaacatc
      181 ggggcggctt attatgtatc ctggtaccaa cagttaccag gaacagcccc caaactcctc
      241 atctttgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggtccctcag cctccctgac catcactgga ctccaatctg aggatgaggc tgattattac
      361 tgtttagcat gggataccag cctgaattgg atcttcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005758             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:19582:16057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005758
VERSION     KCWK01005758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19582:16057"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71496.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           88 a          153 c          128 g          111 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg aggttattat gtgcagtggt accagcagct tccaggagcg
      241 gcccccaaac tcctcatcta tgaaaatgat aaacgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctgattc ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagcttga gtgttgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005759             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:24996:13591
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005759
VERSION     KCWK01005759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24996:13591"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..442
                     /note="immunoglobulin light chain variable region"
     V_region        116..442
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71497.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       410..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>484
                     /gene="IGLC"
BASE COUNT           88 a          156 c          129 g          111 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aagagtgtct ccatctcctg
      181 ttctggaagc agctccaaca tcggaagtca tagtgtctcc tggtaccagc agctcccagg
      241 aacagctccc aaactcctca tctattatag tgatcaacga gcctcaggtg tctctgaccg
      301 attctctggc tctcagtctg gcacgtcagc ctccctggcc atcagtgggc tccaggccga
      361 ggatgaggct gattattact gcgcagcatg ggatgatagt ctgagcggtt acatcttcgg
      421 tgctgggacc cggctcgccg tcgtaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01005760             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:20460:3880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005760
VERSION     KCWK01005760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:20460:3880"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..389
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71498.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       394..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          157 c          118 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc tccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtctc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattata gtgatcaacg agcctcaggt gtctctgacc gattctctgg ctcccagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggacgatag cctgcgcggc tatatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005761             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:8832:4810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005761
VERSION     KCWK01005761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:8832:4810"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71499.1"
                     /translation="DYYCAIGHSSGMFF"
     J_segment       400..435
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          150 c          123 g          112 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctgtgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctatta catacactgg ttccagcaga ggccagggag tcctccccgg tatcttctga
      241 gatacagatc agactctgat aaggaccagg gctctggagt ccccagtcgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtat gtttttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005762             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:6450:15676
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005762
VERSION     KCWK01005762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6450:15676"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71500.1"
                     /translation="DYYCSAWDSSLTGGLF"
     J_segment       406..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          156 c          124 g          106 t
ORIGIN      
        1 acatggggag cttcagctgt ggctagagaa gacaggactc aggacaatct ccagcatggc
       61 ctgcttccct ctcatcctca ccgtcctcac tcactgtgca ggatcctggg cccagtctgt
      121 gctgactcaa ccaccctcag cgtctggggc ccccgggcag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gatgtaattt tgtatactgg taccagcagt tctcagggaa
      241 ggcccccaaa ctcctcatcc ataatagtaa tcagcgaccc tcaggggtcc ctgatcgatt
      301 ctctggctcc aagactggca cgtcagcctc cctggccatc agtgggctcc agtccgagga
      361 tgaggctgac tattactgct cagcatggga tagcagtctg accggtggct tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01005763             417 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:18944:14004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005763
VERSION     KCWK01005763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 417)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:18944:14004"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..379
                     /note="immunoglobulin light chain variable region"
     V_region        58..379
     V_segment       58..343
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <307..>351
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71501.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       344..379
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        380..>417
                     /gene="IGLC"
BASE COUNT           91 a          132 c          104 g           90 t
ORIGIN      
        1 acatggggga ttcctctcct actccccatc ctcactttct gcacaggctc tgcagcctcc
       61 tatgagctga cacagccacc ctcggtgtca gtgtccccag gacagacggc caggatcacc
      121 tgctctggag aagaattgcc aaaaaaatat gcttattggt tccagcagaa gccaggccag
      181 tcccctgtcc agatcatcta tgaggacagt aaacggccct ctgggatccc tgagagattc
      241 tctggctcca gctcagggac agtggccacc ttgactatca ctggggccca ggtggaggat
      301 gaagctgact actactgttt ctcaacagac accagtggta atcgggtatt cggcggaggg
      361 acccgtctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005764             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:11261:13543
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005764
VERSION     KCWK01005764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11261:13543"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71502.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           96 a          151 c          114 g          116 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcg cagcctgtgc tgactcagcc aacctccctc
      121 tcagcatctc ctggagcatc agccagactc acctgcacct tgaacagtgg catcagtgtt
      181 ggtaattaca ggatattctg gtaccaccag aagccaggga gtcctccccg gtatcttctg
      241 aactaccaca cagactcaga tattcatcag gggtctggag tccccagccg cttctctgga
      301 tccaaagatg cttcggccaa tgcagggatt ttactcatct ctggactcca gtctgaggat
      361 gaggctgact attactgtat gatttggcac aacaatgctt attgggtttt cggcggaggg
      421 acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005765             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:10368:8788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005765
VERSION     KCWK01005765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10368:8788"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71503.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          162 c          111 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcctctcc gggagcatca gccagactca gctgcacctt tagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaggatgc ttcggccaat gcaggccttt tagtgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005766             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:18322:16837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005766
VERSION     KCWK01005766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18322:16837"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..439
                     /note="immunoglobulin light chain variable region"
     V_region        92..439
     V_segment       92..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71504.1"
                     /translation="DYYCAIGHSSGNYIF"
     J_segment       406..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           90 a          155 c          120 g          112 t
ORIGIN      
        1 acatgggggg tggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctatgc tgactcagcc ggcctccttc
      121 tcagcatctc ctggagcttc agccagtctc acatgcacct tcagcggtgg catcaatgtt
      181 gctggctacc acatacactg gtaccagcag aagccaggga gtcctccccg gtttcttctg
      241 agatacaagt cagactcaga taagggccag ggctctggag tccccagccg cttctctgga
      301 tccaaggatg cttcagcgaa cacaggaatt ttacgcatct ctgggctcca gtctgaggat
      361 gaggctgact attactgtgc cattgggcac agcagcggta attatatctt cggtgctggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01005767             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:20505:18807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005767
VERSION     KCWK01005767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20505:18807"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71505.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          161 c          118 g          108 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctgact accacataca ctggtaccag cagaagccag ggagtccccc ccggtatctt
      241 ctgaggcaca aatcagactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgctgcagc gaacacaggg attttataca tctctgggct ccagtctgag
      361 gatgaggctg actattactg tgccattggg cacagcagcg gtccttactt cttcggtcct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005768             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:11686:13891
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005768
VERSION     KCWK01005768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11686:13891"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71506.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       389..424
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           87 a          140 c          136 g           99 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatggcctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctatgatct gactcagcca
      121 ccctcgattt cagtgtcccc aggacagacg gccagggtca cctgtggggg agacaacatc
      181 ggaggtgaag ttgtgaattg gtaccagcag aagccaccgc aggcccctgt gttggtcatc
      241 tatggtgata gcgagcggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacacggcca ccctgaccat cagcggggtc gaggccggag atgaggctga ctattactgt
      361 caggtgtggg accttaatag tcatcatctg ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005769             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:22021:16595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005769
VERSION     KCWK01005769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22021:16595"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71507.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       411..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           85 a          163 c          124 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt acttctactc cgactcagac aagcagctgg gacctggggt ccccgatcgc
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtttgaca gtagtgctgt cttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01005770             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:10390:12263
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005770
VERSION     KCWK01005770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10390:12263"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..376
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71508.1"
                     /translation="AYFCQVWDSETDHYIF"
     J_segment       388..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          149 c          127 g           94 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacaga ctctgcgacc tcctatgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaat tttgtgcact ggtaccagca gaagccaccg caggccccta tgcaggtcat
      241 ctatgctgat aacaaacggc cctcagggat ccctgagaga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggagt cgaggccggg gatgaggctg cctatttctg
      361 tcaggtgtgg gacagtgaaa ctgatcatta catcttcggt gctgggaccc ggcttaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005771             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:19262:8511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005771
VERSION     KCWK01005771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19262:8511"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71509.1"
                     /translation="DYYCAAWDDTLSGPVF"
     J_segment       414..448
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           92 a          159 c          129 g          106 t
ORIGIN      
        1 acatggggag cgcagcttca gctgtgggta cagaaggcag gactcaggac aatctccagc
       61 atggcctggt tccctctcct cctcaccctc ctcactcact gtgcagggtc ctgggcccag
      121 tctgtgctga ctcagcctcc ctcagcgtct gaggccgcca ggaagagtgt caccatctcc
      181 tgttctggaa gcagctccaa catcggaagt aatagtgtat cctggtacca gcagctccca
      241 gaaacggctc ccaaactcct catcttttat aatgatcggc gagcctcagg tgtctctgac
      301 cgattctctg gctccaagtc tggcacgtca gcctccctgg ccatcagtgg gctccagacc
      361 gaggatgagg ctgattatta ctgcgcagca tgggatgata ccctgagcgg tccggtattc
      421 ggcggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01005772             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:22698:20336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005772
VERSION     KCWK01005772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22698:20336"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71510.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          162 c          119 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcaatatcgg taataaaaac atgtactggt accagcagaa gccagggagc gctcccaagt
      241 tattcctgta ctactactcc gactcagaca tgcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005773             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:18080:12522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005773
VERSION     KCWK01005773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18080:12522"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71511.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           97 a          143 c          121 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaagaatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tccagatcat
      241 ctatgaggac agtaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 tttctcaaca gacaccagtg gtaatcgggt attcggcgga gggacccgtc taaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005774             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:23506:6732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005774
VERSION     KCWK01005774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23506:6732"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71512.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           94 a          146 c          130 g           94 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca cagactctgc gacctcctat gaactgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccac gatcacctgt gggggagaca
      181 acattggaac taaaactgtg cactggtacc agcagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgatactaaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005775             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:15267:14839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005775
VERSION     KCWK01005775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:15267:14839"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    77..401
                     /note="immunoglobulin light chain variable region"
     V_region        77..401
     V_segment       77..358
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <326..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71513.1"
                     /translation="AYYCQVWDSDSDHYIF"
     J_segment       364..401
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>439
                     /gene="IGLC"
BASE COUNT           87 a          143 c          120 g           89 t
ORIGIN      
        1 acatgggggt gcctcagcca tggcctggac ccttctcctc ctcggcctcc tcgctcactg
       61 cacaggctct gcgacctcct atgagctgac tcagccaccc tcggtgtcag cggcctcagg
      121 acagacggcc aggatcacct gtgggggaga caacattgga actaattttg tgcactggta
      181 ccagcagaag ccagcgcagg cccctatgca ggtcatctat gctgataaca aacggccctc
      241 agggatccct gagagattct ctggctccaa ctcagggaac accgccaccc tgaccatcag
      301 cggagtcgag gccggggatg aggctgccta ttactgtcag gtgtgggaca gtgatagtga
      361 tcattacatc ttcggtgctg ggacccggct caccgtccta ggtcagccca aggcttcccc
      421 cacggtcact ctgttcccg
//
LOCUS       KCWK01005776             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:18990:10013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005776
VERSION     KCWK01005776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18990:10013"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..226
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71514.1"
                     /translation="DYYCQTWETGIQVF"
     J_segment       233..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           61 a           93 c           89 g           58 t
ORIGIN      
        1 acatgggggg cacagcgact acaccatcgc atggcatcag cagcagcaag ggaaggcccc
       61 tcggtatttg atgtggctta aaagtgatgg cagccacagc aagggggacg ggatccctga
      121 tcgcttctcc ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc
      181 tgaggatgag gctgattatt actgtcagac ctgggagact ggcattcagg tgttcggcgg
      241 agggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01005777             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:9825:14172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005777
VERSION     KCWK01005777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:9825:14172"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71515.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       405..439
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           92 a          159 c          112 g          114 t
ORIGIN      
        1 atggggactg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgacccagcc aacctccctc
      121 tcagcatctc cgggagcatc agtcagactc agctgcacct tgagcagtgg catcaatgtt
      181 ggttcttaca ccatattctg gtaccagcag aagccaggga gtcctccccg gttccttctg
      241 tactactact cagactcaaa taatcaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcagccaa tgcagggctt ttactgatct ctggactcca gtctgaagat
      361 gaggctgact attactgtgc catgtggcac agcagcgctt atgccttatt cggaggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005778             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:21593:13062
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005778
VERSION     KCWK01005778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21593:13062"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..429
                     /note="immunoglobulin light chain variable region"
     V_region        96..429
     V_segment       96..392
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71516.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       395..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          155 c          124 g          100 t
ORIGIN      
        1 acatggggtc aggaagcaga gcctggagcg tctccaccat ggcctgggct ccactcctcc
       61 tcaccctcct cgctcactgc acagggtctt gggctgaggt tctgttcacg cagccccatt
      121 ctgtgtcggg gtctccgggg cagacggtca ccatctcctg tacccgcagc agaggcaaca
      181 ttgacaatag ttatgtgcag tggtaccagc agcgcccggg cagtgccccg accacagtga
      241 tttacagaga taaccaaaga gcctctgggg tccctgatcg gttctctggc tccatcgaca
      301 gctcctccaa ctctgcctcc ctcaccatct ctgggctgaa gtctgaggac gaggctgact
      361 actactgtca gtctactgat ggcaactaca atcggttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005779             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:8129:7260
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005779
VERSION     KCWK01005779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8129:7260"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71517.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          150 c          115 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactatacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005780             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:13771:20420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005780
VERSION     KCWK01005780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13771:20420"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71518.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          161 c          111 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tgctgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005781             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:8967:17494
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005781
VERSION     KCWK01005781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8967:17494"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71519.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       411..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          155 c          129 g          113 t
ORIGIN      
        1 acatgggggg ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggaggt tattatgtgc agtggtacca acagcttcca
      241 ggaacggccc ccaaactcct catctatgaa aatgataaac gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tgattcctca gcctccctga ccgtcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gcttgagtgt tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01005782             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:25114:11630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005782
VERSION     KCWK01005782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:25114:11630"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..432
                     /note="immunoglobulin light chain variable region"
     V_region        103..432
     V_segment       103..389
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71520.1"
                     /translation="DYYCSSFAGRNNLFF"
     J_segment       403..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>471
                     /gene="IGLC"
BASE COUNT           86 a          155 c          118 g          112 t
ORIGIN      
        1 catggggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cccgactcag
      121 cctccctctg tgtccgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtaatcttg ggtattttaa tgctgtgtct tggtaccaac aacatccagg caaagccccc
      241 aaactcatga tttacgacgt cactaagcgg ccctcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccaggctga ggatgaggct
      361 gattattact gcagttcatt tgccggcagg aacaatttat ttttcggagg agggacccgg
      421 ctgaccgtcc taagtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005783             500 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16488:13306
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005783
VERSION     KCWK01005783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 500)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16488:13306"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    132..462
                     /note="immunoglobulin light chain variable region"
     V_region        132..462
     V_segment       132..423
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <390..>434
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71521.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       425..462
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        463..>500
                     /gene="IGLC"
BASE COUNT           93 a          155 c          139 g          113 t
ORIGIN      
        1 acatggggag ggagagattt ggggaagctc tgcttcagct gtgggcacag gaggcagcac
       61 tcaggacagt ctccagcatg gcctggtctc tccttctcac tctgctggtt cactgcacag
      121 ggtcctgggc ccagtctgtg ctgacgcagc cgccctcagc atctggggcc cccggacaga
      181 ggattaccat ctcctgcact gggaccaggt ccaacatcgg ggcgggtttt tatgtgtcct
      241 ggtaccagca gttccctggg acagccccca aactcctcat ctttgaaaat aataagcgac
      301 cctcagggct ttctgaccga ttctctggct ccaagtctgg gtcctcagcc tccctgacca
      361 tcactggact ccagtctgag gatgaggctg attattactg ctcatcatgg gaaagcagcc
      421 tgaattgggt attcggcgga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      481 cctcggtcac tctcttcccg
//
LOCUS       KCWK01005784             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:10455:12791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005784
VERSION     KCWK01005784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10455:12791"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71522.1"
                     /translation="VYYCAIGHSSGLYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           88 a          158 c          120 g          113 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgtcta ccacgtacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgaggtacaa atcagactca gataagggcc agggctctgg ggtccccagc cgcttctctg
      301 gatccagtaa tgcttcagcg aacacaggga ttttacgcat ttctgggctc cagtctgagg
      361 atgaggctgt ctattactgt gccattgggc acagcagcgg tctttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005785             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:21526:1920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005785
VERSION     KCWK01005785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21526:1920"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71523.1"
                     /translation="GYYCQVYDSSTDVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           88 a          164 c          126 g          108 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcgtcccc gggagcatcg gccagactcc cctgcaccct gaccagtgac
      181 ctcagcgttg gtagtaaaaa catgtattgg taccagcaga agccagggag cgctcccagg
      241 tcattcctct actactattc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac gtcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccggcta ttactgtcag gtgtatgaca gcagtactga tgtgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01005786             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:11913:7323
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005786
VERSION     KCWK01005786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11913:7323"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71524.1"
                     /translation="DYYCAIGHSSGPYSF"
     J_segment       410..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          162 c          120 g          106 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgacta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgagatacag atcagactca gataagggcc agggctctgg agtcccccgc cgcttctctg
      301 gatccaaaga tgctgcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctactactgt gccattgggc acagcagcgg tccttactcc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005787             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:27541:16590
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005787
VERSION     KCWK01005787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:27541:16590"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71525.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          163 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg accaggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005788             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:11688:7178
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005788
VERSION     KCWK01005788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11688:7178"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..431
                     /note="immunoglobulin light chain variable region"
     V_region        107..431
     V_segment       107..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71526.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       394..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           91 a          147 c          132 g           99 t
ORIGIN      
        1 acatggggct gtctgggtct caggaggcag cattgacggt gcctcagcca tggcctggac
       61 ccttctcctc ctcggcctcc tcgctcactg cacaggctct gcgacctcct ttgagttgac
      121 tcagccaccc tcggtgtcag cggcctcagg acagacggcc aggatcacct gtgggggaga
      181 caacattgga attaaatttg tccactggta ccagcagaag ccagcgcagg cccctgtgaa
      241 ggtcatctat gctgatgaca aacggccctc agggatccct gagagattct ctggctccaa
      301 ttcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      361 ttcctgtcag gtgtgggaca gtgagactga ttattacatc ttcggtactg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005789             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:11265:14246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005789
VERSION     KCWK01005789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:11265:14246"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..451
                     /note="immunoglobulin light chain variable region"
     V_region        115..451
     V_segment       115..408
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71527.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       414..451
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT           96 a          158 c          123 g          112 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg gttcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agcatctggg gcccccgggc agagggtcac catctcctgc
      181 actgggagca gctccaacat cggggcgggt tattatgtat cctggtacca gcagttccca
      241 ggaacagccc ccaaactcct catctatgaa aataataaac gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggtacctca gcctccctga ccatcactgg actccaatct
      361 gaggatgagg ctgattatta ctgctcagca tgggatagca gcctgagtat caattacatc
      421 ttcggttctg ggacccgtct caccgtccta ggtcagccca aggcttcccc cacggtcact
      481 ctgttcccg
//
LOCUS       KCWK01005790             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:7587:11936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005790
VERSION     KCWK01005790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7587:11936"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..251
                     /note="immunoglobulin light chain variable region"
     V_region        1..251
     V_segment       1..214
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71528.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       215..251
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           60 a           90 c           73 g           66 t
ORIGIN      
        1 caacatcgga agtcatagtg tatcctggta ccagcagctc ccaggaacag ctcccaaact
       61 cctcatctat tatgatgatc aacgagcctc aggtgtctct gaccgattct ctggctccag
      121 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      181 ttactgcgca gcatgggatg atagcctgag aggttacatc ttcggtgatg ggacccggct
      241 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005791             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:17493:8931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005791
VERSION     KCWK01005791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17493:8931"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..425
                     /note="immunoglobulin light chain variable region"
     V_region        105..425
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71529.1"
                     /translation="DYFCQVWDSGSDHYIF"
     J_segment       392..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>467
                     /gene="IGLC"
BASE COUNT           86 a          148 c          133 g          100 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagttgactc
      121 agccaccctc ggtgtcagcg gcctctggac agacggccag gatcacctgt gggggagaca
      181 acattggaac tacatatgtg cactggtacc agcagaagcc accacaggcc cctgtgcagg
      241 tcatctttgc tgatagcaaa cggccctcag gggtccctga ccgattctct ggctccaact
      301 cagggaacac cgccaccttg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 tctgtcaggt gtgggacagt ggtagtgatc attacatctt cggtgttggg acccggctca
      421 ccgtcttagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01005792             361 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:14625:18967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005792
VERSION     KCWK01005792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 361)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14625:18967"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..323
                     /note="immunoglobulin light chain variable region"
     V_region        8..323
     V_segment       8..285
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <248..>295
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71530.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       287..323
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        324..>361
                     /gene="IGLC"
BASE COUNT           76 a          117 c           87 g           81 t
ORIGIN      
        1 acatgggcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
       61 tggaagcacc tccaacatcg gaagcaataa tgtatcctgg taccagcagc tcccaggaac
      121 agctcccaaa ctcctctttt attataatga tcaacgagcc tcaggtgtct ctgaccgatt
      181 ctcttgctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      241 tgaggctgat tattactgcg cagcatggga tgataacctg agcggctaca tcttcggtgc
      301 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      361 g
//
LOCUS       KCWK01005793             293 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:24678:4667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005793
VERSION     KCWK01005793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 293)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24678:4667"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..255
                     /note="immunoglobulin light chain variable region"
     V_region        8..255
     V_segment       8..218
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <180..>227
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71531.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       219..255
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        256..>293
                     /gene="IGLC"
BASE COUNT           56 a           93 c           76 g           68 t
ORIGIN      
        1 acatgggcat cggaagtcat agtgtctcct ggtaccagca gctcccagga acagctccca
       61 aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga ttctctggct
      121 ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag gatgaggctg
      181 attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt gctgggaccc
      241 ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005794             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:12092:18099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005794
VERSION     KCWK01005794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12092:18099"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71532.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       393..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          137 c          135 g          105 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggaaaga cggccaggat cacctgtggg ggagacaata
      181 ttggaagtga agttgtcaac tggtaccagc agaagccacc gcaggcccct gtggtggtca
      241 tctatgctga ttatgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagtggag tcgaggccgg ggatgaggct gactattact
      361 gtcaggtttg ggacatttat attgatcatc cggtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005795             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:17000:4454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005795
VERSION     KCWK01005795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17000:4454"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..400
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71533.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       401..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           82 a          157 c          129 g          106 t
ORIGIN      
        1 acatgggggg ggggtctcag gaggcagcgc tctcgggacg tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcagtc tgccctgact
      121 cagcctccct cagtgtccaa gtctcttgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgaca ttggtggtta tgatggcgtc tcctggtacc agcagcactc agggacagcc
      241 cccagactcc tgatttatga tgtcactaag cggccctcag gggtctcgga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctc accatctctg ggctccagac tgaggacgag
      361 gctgattatt actgttgctc atataggagt ggaaacactt ggctattcgg cggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005796             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:10460:18329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005796
VERSION     KCWK01005796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10460:18329"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71534.1"
                     /translation="DYSCCSYRSGNTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           81 a          158 c          128 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt atgatggcgt ctcctggtac cagcagcact cagggacagc
      241 ccccagactc ctgatttatg atgtcactaa gcggccctca ggggtctcgg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct caccatctct gggctccaga ctgaggacga
      361 ggctgattat tcttgttgct catataggag tggaaacact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005797             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:18785:6263
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005797
VERSION     KCWK01005797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18785:6263"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71535.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       404..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           97 a          155 c          111 g          116 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgaacagt ggcatcagtg
      181 ttgctaatta caggatattc tggtaccacc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gatattcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttattgggtt ttcggcggag
      421 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005798             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10317:16953
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005798
VERSION     KCWK01005798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10317:16953"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..446
                     /note="immunoglobulin light chain variable region"
     V_region        101..446
     V_segment       101..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71536.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       409..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           86 a          162 c          124 g          112 t
ORIGIN      
        1 acatgggggt gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagcagtga
      181 cctcagtgtt ggtagtaaaa acatgtactg gtaccagcag aagccaggga gcgctcccag
      241 gttattcctg tactactact ccgactcaga caagcagctg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt atttctgcca ggtgtttgac agtagtgttg tgttcttcgg
      421 aggagggacc cgactgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01005799             337 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:3864:17252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005799
VERSION     KCWK01005799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 337)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 337)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..337
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:3864:17252"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..299
                     /note="immunoglobulin light chain variable region"
     V_region        8..299
     V_segment       8..261
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>271
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71537.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       267..299
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        300..>337
                     /gene="IGLC"
BASE COUNT           71 a           99 c          106 g           61 t
ORIGIN      
        1 acatggggtg tccccaggac agacggccag gatcacctgc gggggagaca agattggaag
       61 tgaagttgtg aactggtacc agcagaagcc agcgcacgcc cctgtgctgg tcatctatgc
      121 taatagcgaa cggccctcag ggatccctga gcgattctct ggctccaaat cagggaacac
      181 ggccaccctg accatcagcg gggtcgaggc cgggggtgag gctgactatt actgtcaggt
      241 gtgggacatg cgtagtgatc aaccgctatt cggcggaggg acccggctaa ccgtcctagg
      301 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005800             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:20292:13858
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005800
VERSION     KCWK01005800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20292:13858"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71538.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          146 c          132 g           97 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggttctgcga cctcctttga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaatta aatttgtcca ctggtaccag cagaagccag cgcaggcccc tgtgaaggtc
      241 atctatgctg atgacaaacg gccctcaggg atccctgaga gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattcc
      361 tgtcaggtgt gggacagtga gactgattat tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005801             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:12889:13209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005801
VERSION     KCWK01005801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12889:13209"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71539.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          143 c          142 g           92 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgcggg ggagacaaga
      181 ttggaagtga agttgtgaac tggtaccagc agaagccagc gcaggcccct gtgctggtca
      241 tctatgctga tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacacggc caccctgacc atcagcgggg tcgaggccgg gggtgaggct gactattact
      361 gtcaggtgtg ggacatgcgt agtgatcaac cgctattcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005802             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:7398:10823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005802
VERSION     KCWK01005802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7398:10823"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..385
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71540.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       398..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           85 a          150 c          137 g           94 t
ORIGIN      
        1 acatgggggc tgggtctcag gaggcagcat tgacggtgcc tcagccatgg cctggaccct
       61 tctcctcctc ggcctcctcg ctcactgcac aggctctgcg gcctcctatg agctgactca
      121 gccaccctcg gtgtcagcgg cctcaggaca gacggccagg atcccctgtg ggggagacaa
      181 cattggaact aaatatgtgc actggtacca gcagaagcca gcgcaggccc ctgtgttggt
      241 catctatgct gataccagac ggccctcagg gatccctgag cgattctctg gctccaactc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggatatgagg ctgactattt
      361 ctgtcaggtg tgggacgata gtagtgatca tccggttttc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005803             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:26675:19555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005803
VERSION     KCWK01005803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:26675:19555"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71541.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          155 c          118 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga gatcccgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacacttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005804             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:7926:21734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005804
VERSION     KCWK01005804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7926:21734"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71542.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          147 c          131 g           95 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctcgggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005805             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:25791:15817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005805
VERSION     KCWK01005805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:25791:15817"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..251
                     /note="immunoglobulin light chain variable region"
     V_region        1..251
     V_segment       1..214
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71543.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       215..251
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           59 a           90 c           74 g           66 t
ORIGIN      
        1 caacatcgga agtcatagtg tatcctggta ccagcagctc ccaggaacag ctcccaaact
       61 cctcatctat tatgatgatc aacgagcctc gggtgtctct gaccgattct ctggctccag
      121 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      181 ttactgcgca gcatgggatg atagcctgag aggttacatc ttcggtgatg ggacccggct
      241 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005806             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:3188:7911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005806
VERSION     KCWK01005806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:3188:7911"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71544.1"
                     /translation="DYYCQVWDSSSEWVF"
     J_segment       391..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          143 c          137 g           93 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca cagactctgc gacctcctat gagttgactc
      121 aggcaccctc agtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taaaactgtg cactggtacc aacagaaggc agcgcaggcc cctgtgctgg
      241 tcatctttgc tgatagcaaa cggccctcag ggatccctga ccgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgaat gggttttcgg cggagggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005807             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11134:10664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005807
VERSION     KCWK01005807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11134:10664"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..451
                     /note="immunoglobulin light chain variable region"
     V_region        121..451
     V_segment       121..414
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71545.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       415..451
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT           91 a          159 c          123 g          116 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggact ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcacttca cagttccagg gtcctgggcc
      121 cagtctgtgc tgacgcagcc gccctcagtg tctggggcgc ccggacagag ggtcaccatc
      181 tcctgcactg ggagcagctc caacattgga gattattttg tgcagtggta ccagcacctt
      241 ccaggaacgg cccccaaact cctcatctat gaaaataata agcgaccctc agggatttct
      301 gatcgattct ctggctccca gtctggaacc tcagcctccc tgaccatcac tggactccag
      361 tctgaggatg aggctgatta ttactgccag tcctatgaca gcagtttgat tgctgtgtta
      421 ttcggaggcg ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCWK01005808             408 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:21201:16644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005808
VERSION     KCWK01005808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 408)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:21201:16644"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    22..370
                     /note="immunoglobulin light chain variable region"
     V_region        22..370
     V_segment       22..333
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <298..>342
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71546.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       334..370
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        371..>408
                     /gene="IGLC"
BASE COUNT           83 a          132 c          104 g           89 t
ORIGIN      
        1 acatgggcag gttccctctc ccagcctgtg ctgactcagc caccctccct gtctgcatcc
       61 ccgggagcat cggccagact cccctgcacc ctgagcagtg acctcagtgt tggtagtaaa
      121 aacatgtact ggtaccagca gaagccaggg agcgctccca ggtcattcct gtactactac
      181 tccgactcag acaagcagct gggacctggg gtccccaatc gagtctctgg ctccaaggag
      241 acctcaacta acacagcgtt tttgctcatc tctggactcc agcctgagga cgaggccgat
      301 tattactgtc aggtgtatga cagtagtgct aatgtgttat tcggaggagg gacccggctg
      361 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005809             400 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:21239:19826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005809
VERSION     KCWK01005809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 400)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 400)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21239:19826"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..362
                     /note="immunoglobulin light chain variable region"
     V_region        14..362
     V_segment       14..325
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <290..>334
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71547.1"
                     /translation="DYYCAIGHSSGPYFF"
     J_segment       326..362
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        363..>400
                     /gene="IGLC"
BASE COUNT           81 a          130 c          101 g           88 t
ORIGIN      
        1 acatgggctc tccaagccta tgctgactca gccggcctcc ctctcagcat ctcctggagc
       61 atcagccagt ctcacatgca ccttcagcgg tggcatcaat gttgctgact accacataca
      121 ctggtaccag cagaagccag ggagtccccc ccggtatctt ctgagataca gatcagactc
      181 agataagggc cagggctctg gagtccccag ccggttctct ggatccaaag atgctgcagc
      241 gaacacaggg attttacgca tctctgggct ccagtctgag gatgaggctg actattactg
      301 tgccattggg cacagcagcg gtccttactt cttcggtgct gggacccggc tcaccgtcct
      361 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005810             490 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:13060:19002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005810
VERSION     KCWK01005810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 490)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13060:19002"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    128..452
                     /note="immunoglobulin light chain variable region"
     V_region        128..452
     V_segment       128..414
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>424
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71548.1"
                     /translation="DYYCQVWDTTLDHGLF"
     J_segment       416..452
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>490
                     /gene="IGLC"
BASE COUNT           98 a          153 c          139 g          100 t
ORIGIN      
        1 acatgggaag cagtggcaac gcagagtaca tgggggggcc tcaggaggca gcattgacgg
       61 tgcctcagcc atggcctgga cttttctcct cctcggcctc cttgcttact gcacaggctc
      121 tgcggcctcc tatgatctga ctcagccacc ctcggtgtca gtgtccccag gacagacggc
      181 caggatcacc tgtgggggag acaacattgg aagtcaaagt gtgcactggt accagcacaa
      241 gccaccgcag gcccctgttc tggtcatctt ttattatacc gaacggccct caggaatccc
      301 tgagcgattc tctggctcca aatcagggaa caccgccacc ctgaccatca gcggggtcga
      361 ggccggggat gaggctgact attactgtca ggtgtgggac acaactcttg atcacggctt
      421 attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac
      481 tctcttcccg
//
LOCUS       KCWK01005811             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:8003:11588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005811
VERSION     KCWK01005811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8003:11588"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..396
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71549.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           93 a          154 c          119 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcatctcctg gaacatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgtt
      181 ggctaccaca tacactggta ccagcagaag ccagggagtc ctccccggta tcttctgaga
      241 tacaaatcgg actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagcgaacgc agggatttta cgcatctctg gactccagtc tgaggatgag
      361 gctgactatt actgtgccat tgggcacagc agcggtgatt acatcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005812             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:17744:3596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005812
VERSION     KCWK01005812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17744:3596"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..444
                     /note="immunoglobulin light chain variable region"
     V_region        97..444
     V_segment       97..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71550.1"
                     /translation="DYYCAIGHSSGNYIF"
     J_segment       411..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          159 c          119 g          113 t
ORIGIN      
        1 acatggggcc cactgtgggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcccagcc tatgctgact cagccggcct
      121 ccttctcagc atctcctgga gcttcagcca gtctcacatg caccttcagc ggtggcatca
      181 atgttgctgg ctaccacata cactggtacc agcagaagcc agggagtcct ccccggtttc
      241 ttctgagata caagtcagac tcagataagg gccagggctc tggagtcccc agccgcttct
      301 ctggatccaa ggatgcttca gcgaacacag gaattttacg catctctggg ctccagtctg
      361 aggatgaggc tgactattac tgtgccattg ggcacagcag cggtaattat atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01005813             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11722:8663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005813
VERSION     KCWK01005813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11722:8663"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71551.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       420..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           95 a          158 c          127 g          108 t
ORIGIN      
        1 acatgggggg ggaagctctg cttcagctgt gggcacagga ggcagcactc aggacagtct
       61 ccagcatggc ctggtctctc cttctcactc tgctggttca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagcat ctggggcccc cggacagagg gtcaccatct
      181 cctgcattag cagcagctcc aacatcgggg cggcttatta tgtatcctgg taccaacagt
      241 tcccaggaac agcccccaaa ctcctcatcc atgaaaataa taagcgaccc tcaggggttt
      301 ctgaccgatt ctctggctcc aagtctggtc cctcagcctc cctgaccatc actggactcc
      361 aatctgagga tgaggctgat tattactgtt tagcatggga taccagcctg aattggatct
      421 tcggcggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01005814             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:21570:16568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005814
VERSION     KCWK01005814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21570:16568"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71552.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       394..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           92 a          144 c          134 g           94 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gcttactgca cagggtctgc gacctcctat gaactgactc
      121 agtcaccctc agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagcca
      181 acattggaac taaaactgtg cactggtacc agcagaagcc accgcagggc cctgtattgg
      241 tcatctttgc tgatagtaaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005815             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:16652:22290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005815
VERSION     KCWK01005815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16652:22290"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71553.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          142 c          142 g           93 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tggaagtgaa gttgtgaact ggtaccagcg gaagccagcg caggcccctg tgctggtcat
      241 ctatgctgat agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg ggtgaggctg actattattg
      361 tcaggtgtgg gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005816             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:9049:9232
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005816
VERSION     KCWK01005816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:9049:9232"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71554.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       397..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           90 a          159 c          120 g          102 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgtct ctgcctccct gggagcctcg gtcaaactca cctgtacttt gaacagtggg
      181 cacagcagct acaccatcgc atggcatcag cagcagcaag tgaaggcccc ccggtacttg
      241 atgtggctta aaagtgaagg cagccatagc aagggggacg ggatccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc accatctcca acctccagtc tgaggatgag
      361 gctgattatt actgtcagac ctgggatact gacattgtgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005817             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:17110:7762
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005817
VERSION     KCWK01005817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:17110:7762"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..258
                     /note="immunoglobulin light chain variable region"
     V_region        10..258
     V_segment       10..218
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <180..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71555.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       222..258
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           61 a           82 c           86 g           67 t
ORIGIN      
        1 acatgggtat tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg
       61 tggtggtcat ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct
      121 ccaaatcagg gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg
      181 actattactg tcaggtttgg gacatttata ttgatcatcc ggtgttattc ggaggaggga
      241 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005818             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:19595:4842
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005818
VERSION     KCWK01005818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:19595:4842"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71556.1"
                     /translation="DYYCQSADSSSHHYIF"
     J_segment       396..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT          105 a          134 c          121 g          107 t
ORIGIN      
        1 acatgggggg ctgtggttct aggaggaaga gctctgggtg tctcaccatg acctggacca
       61 ctgttctgct cccctttctc actctctgca caggctctga ggcctcctat gaactgacac
      121 agccaccctc agtgtcagtg tccccaggac agacggccag gatcacctgc tctggagaaa
      181 tgctggaaaa aaaatatact cagtggttcc agcggaagcc aggccaggcc cctgttttgg
      241 tgatctataa agacagtgag aggccctcag ggatccctga gcgattctct agttccagtt
      301 cagggacaac agttaccttg accatcagtg gggcccaggc agaagatgag gctgactatt
      361 attgtcaatc agcagacagt agtagtcatc attatatctt cggtcctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01005819             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:8378:10172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005819
VERSION     KCWK01005819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8378:10172"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71557.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          152 c          112 g          119 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgagcagt ggcttcagtg
      181 ttggtactta caggatattc tggtaccatc agaagccagg gagtcctccc cggtatcttc
      241 ttaactacca cacagactca gataagcacc aggactctgg agtccccagc cgcttctttg
      301 gatccaaaga tgtttcggcc aatgcaggga ttttactcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttatgtctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005820             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:3026:13282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005820
VERSION     KCWK01005820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:3026:13282"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..438
                     /note="immunoglobulin light chain variable region"
     V_region        105..438
     V_segment       105..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71558.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       402..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           87 a          161 c          122 g          106 t
ORIGIN      
        1 acatggggtg gggtctcagg aggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggttat aactatgtct cctggtacca acaacatcca gacacagccc
      241 ccaaactcgt gatttatgag gtcaatcagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tgacaacacg gcctccctga ccatctctgg cctccagcct gaggacgagg
      361 ctgattatta ctgcagctca tatgcaggca gcgacacttt cgtgttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005821             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:26426:18136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005821
VERSION     KCWK01005821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:26426:18136"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..242
                     /note="immunoglobulin light chain variable region"
     V_region        10..242
     V_segment       10..203
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <167..>214
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71559.1"
                     /translation="VYYCGAWDSSLSGYIF"
     J_segment       205..242
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        243..>280
                     /gene="IGLC"
BASE COUNT           53 a           87 c           74 g           66 t
ORIGIN      
        1 acatgggtct gtatcctggt accagcaggt cccaggaacg gcccccaaag tcctcatcta
       61 tgacaataat aagcgcccct cgggggtttc tgaccgattc tctggctcca agtctggtac
      121 ctcagcctcc ctggccatca ctggactcca ggctggagat gaggctgttt attactgcgg
      181 agcatgggat agcagtctga gtggttacat cttcggtgat gggacccggc tcaccgtcct
      241 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005822             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:18398:13811
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005822
VERSION     KCWK01005822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18398:13811"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71560.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          161 c          119 g          108 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcaactgcac cttgagcagt ggcgtcaatg
      181 tgggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacca gtcagactca aggaagcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc tgttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccctatggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005823             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:15835:13812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005823
VERSION     KCWK01005823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15835:13812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..258
                     /note="immunoglobulin light chain variable region"
     V_region        5..258
     V_segment       5..218
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <186..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71561.1"
                     /translation="VYYCQVWDSSSEWVF"
     J_segment       222..258
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           64 a           86 c           86 g           60 t
ORIGIN      
        1 acatgggaga caacattgga actaaaactg tgcactggta ccaacagaag gcagcacagg
       61 cccctatgct ggtcatcttt gctgatagca aacggccctc agggatccct gaccgattct
      121 ctggctccaa ctcagggaac accggcaccc tgaccatcag cggggtcgag gccggggatg
      181 aggctgtcta ttactgtcag gtgtgggaca gtagtagtga gtgggttttc ggcggaggga
      241 cccgtctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005824             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:16378:5237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005824
VERSION     KCWK01005824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:16378:5237"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71562.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          154 c          121 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccagcatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacgcttta ttcttcggag gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005825             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:14381:14733
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005825
VERSION     KCWK01005825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14381:14733"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..382
                     /note="immunoglobulin light chain variable region"
     V_region        89..382
     V_segment       89..345
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <307..>354
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71563.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       348..382
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>420
                     /gene="IGLC"
BASE COUNT           79 a          126 c          127 g           88 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gtgtccccag gacagacggc cagggtcacc
      121 tgtgggggag acaacatcgg aggtgaagtt gtgaattggt accagcagaa gccaccgcag
      181 gcccctgtgt tggtcatcta tgctgatagc gagcggccct cagggatccc tgagcgattc
      241 tctggctcca aatcagggaa cgcggccacc ctgaccatca gcggggtcga ggccggagat
      301 gaggctgact attactgtca ggtgtgggac cttaatagtc atcatctctt attcggagga
      361 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005826             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:20700:11654
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005826
VERSION     KCWK01005826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20700:11654"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71564.1"
                     /translation="VYYCAIGHSSGLYIF"
     J_segment       402..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           87 a          157 c          121 g          112 t
ORIGIN      
        1 acatgggggg tggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc aagcctatgc tgactcagcc ggcctccctc
      121 tcagcatctc ctggagcatc agccagtctc acatgcacct tcagcggtgg catcaatgtt
      181 gctgtctacc acgtacactg gtaccagcag aagccaggga gtcccccccg gtatcttctg
      241 aggtacaaat cagactcaga taagggccag ggctctgggg tccccagccg cttctctgga
      301 tccagtaatg cttcagcgaa cacagggatt ttacgcattt ctgggctcca gtctgaggat
      361 gaggctgtct attactgtgc cattgggcac agcagcggtc tttacatctt cggtgctggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01005827             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:11237:21636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005827
VERSION     KCWK01005827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11237:21636"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..289
                     /note="immunoglobulin light chain variable region"
     V_region        8..289
     V_segment       8..252
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <214..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71565.1"
                     /translation="DYYCQSYDRSLNAVLF"
     J_segment       253..289
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           68 a           96 c           86 g           77 t
ORIGIN      
        1 acatgggggg tcaccatctc ctgcactggg agcagctcca acattggaga ttattatgtg
       61 cagtggtacc agcagcttcc aggcacggcc cccagactcc tcatctatga aaatgataga
      121 cgacgctcag gggcttctga tcgattctct ggctcccagt ctggtacctc agcctcgctg
      181 accataagtg gactccagtc tgaggatgag gctgactatt actgccagtc ttatgacaga
      241 agcttgaatg ctgtgttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      301 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005828             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:8875:15389
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005828
VERSION     KCWK01005828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:8875:15389"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71566.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          152 c          122 g          112 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg tacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005829             263 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:16820:11852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005829
VERSION     KCWK01005829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 263)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 263)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..263
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16820:11852"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..225
                     /note="immunoglobulin light chain variable region"
     V_region        6..225
     V_segment       6..188
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <150..>197
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71567.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       190..225
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        226..>263
                     /gene="IGLC"
BASE COUNT           51 a           78 c           81 g           53 t
ORIGIN      
        1 atgggcagca gaagccaccg caggcccctg tgttggtcat gtatgctgat agcgagcggc
       61 cctcagggat ccctgagcga ttctctggct ccaaatcagg gaacacggcc accctgacca
      121 tcagcggggt cgaggccggg gatgaggctg actattactg tcaggtgtgg gacatgaata
      181 gtcatcatct gttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg
      241 ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005830             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:27452:7146
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005830
VERSION     KCWK01005830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:27452:7146"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..312
                     /note="immunoglobulin light chain variable region"
     V_region        8..312
     V_segment       8..273
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71568.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       275..312
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>350
                     /gene="IGLC"
BASE COUNT           72 a          105 c           95 g           78 t
ORIGIN      
        1 acatgggggg agcatcggcc agactcccct gcaccctgag cagtgacctc agtgttggta
       61 gtaaaaacat gtactggtac cagcagaagc cagggagcgc tcccaggtta ttcctgtact
      121 actactccga ctcagacaac cagctgggac ctggggtccc caatcgagtc tctggctcca
      181 aggagacctc aagtaacaca gcgtttttgc tcatctctgg gctccagcct gaggacgagg
      241 ccgattattt ctgccaggtg tttgacagta gtgttgtgtt cttcggagga gggacccgac
      301 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005831             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:10663:3948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005831
VERSION     KCWK01005831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10663:3948"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..403
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71569.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          153 c          118 g          115 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcgcagcctg tgctgactca gccaacctcc
      121 ctctcagctt ctcctggagc atcagccaga ctcacctgca ccttgagcag tggcatcagt
      181 gttggtactt acaggatatt ctggtaccag cagaggccag ggagtcctcc ccggtatctt
      241 ctgaaccacc acacagactc agataaacat cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatgcaggg attttgctca tctctgggct ccagtctgag
      361 gatgaggctg actattactg tatgatttgg cacaacaatg cttatgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005832             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:22249:8612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005832
VERSION     KCWK01005832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22249:8612"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71570.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          163 c          111 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccagc agaagccagg gagtcccccc cggtatcttc
      241 tgacttacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaaa tgcttcaacg aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005833             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:15114:12145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005833
VERSION     KCWK01005833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15114:12145"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..391
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71571.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       392..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          152 c          118 g          103 t
ORIGIN      
        1 acatggggga cagaaggcag gactcaggac aatctccagc atggcctggt tccctctcgt
       61 cctcaccctc ctcactcact gtgcagggtc ctgggcccag tctgtgctga ctcagcctcc
      121 ctcagcgtct gaggccgcca ggaagagtgt caccatctcc tgttctggaa gcagctccaa
      181 catcggaagt aataatgtgt cctggtacca gcacctccca ggaacagctc ccaaactcct
      241 catctattat aatgatcaac gaggctcagg tgtctctgac cgattctctg gctccaagtc
      301 tggcacgtca gcctccctgg ccatcagtgg gctccagacc gaggatgagg ctgattatta
      361 ctgcgcagcg tgggatgata ggctgagcag ttacatcttc gctgctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005834             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:21718:11325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005834
VERSION     KCWK01005834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21718:11325"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71572.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          139 c          140 g           96 t
ORIGIN      
        1 acatggggct gactttggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactttacag gctctgcggc ctcctatgag gtgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa aagtgtgcag tggtaccagc agacgccacc gcaggcccct gtactggtca
      241 tttatggtga tagggaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggatagcagt agtaaatatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005835             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:17418:10911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005835
VERSION     KCWK01005835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:17418:10911"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71573.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          162 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca aacagctggg acctggggtc cacaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005836             382 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:18409:6917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005836
VERSION     KCWK01005836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 382)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18409:6917"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..344
                     /note="immunoglobulin light chain variable region"
     V_region        20..344
     V_segment       20..301
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <269..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71574.1"
                     /translation="DYFCQVWDSISDHPLF"
     J_segment       310..344
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>382
                     /gene="IGLC"
BASE COUNT           79 a          117 c          111 g           75 t
ORIGIN      
        1 acatggggcc tctgcgacct cctatgagct gactcagcca ccctcggtgt cagcggcctc
       61 aggacagacg gccaggatca cctgtggggg agacaacatt ggaactaaat atgtgcactg
      121 gtaccagcag aagccagcgc aggcccctgt gcaggtcatt tatggtgata ccaaacggcc
      181 ctcagggatc cctgagcgat tctctggctc caactcaggg aacaccgcca ccctgaccat
      241 cagcggggtc gaggccgggg atgaggctga ctatttctgt caggtgtggg acagtattag
      301 tgatcatccc ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc
      361 cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005837             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:20263:22539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005837
VERSION     KCWK01005837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20263:22539"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71575.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          148 c          130 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaaccccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005838             338 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:21231:5124
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005838
VERSION     KCWK01005838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 338)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21231:5124"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..300
                     /note="immunoglobulin light chain variable region"
     V_region        8..300
     V_segment       8..264
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>272
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71576.1"
                     /translation="DYYCAVWSSSAYIF"
     J_segment       265..300
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        301..>338
                     /gene="IGLC"
BASE COUNT           63 a          104 c           86 g           85 t
ORIGIN      
        1 acatgggcag actcacctgc accttgcgca ctggcctcaa tgttggtggc tactacatat
       61 tctggtacca gcagaagcca gggagtcctc cccggttcct tctgaattac tactcagact
      121 caaatcaggg ccagggctct ggagtcccca gccgcttctc tggatccaaa gatgtttcag
      181 ccaatgcagg gcttttactg atctctgggc tccagtctga ggatgaggct gactattact
      241 gtgccgtttg gtccagcagc gcttacatct tcggtggtgg gactcggctc accgtcctag
      301 gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01005839             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:11500:10618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005839
VERSION     KCWK01005839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11500:10618"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71577.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           96 a          153 c          112 g          115 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcatctcc tggagcatca gccagactca cctgcacctt gagcagtggc ttcagtgttg
      181 gtacttacag gatattctgg taccagcaga agccagggag tcctccccgg tatcttctta
      241 actaccacac agactcagat aaacaccagg actctggagt ccccagccgc ttctttggat
      301 ccaaagatgc tccggccaat gcagggattt tactcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtatg atttggcaca acaatgctta tgtcttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005840             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:13061:3662
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005840
VERSION     KCWK01005840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13061:3662"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..388
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71578.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          148 c          120 g          108 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc acgatctcct gcagtgggag caactccaac
      181 attggatatt attatgtgca gtggtaccag cagcttccag gaacggcccc caaactcctc
      241 atctatgaaa ataataagcg accctctggg gtttctgatc gattctctgg ctcccagtct
      301 ggtacctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgccactcct atgacagcag tttgagtggt gtcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005841             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:21994:8071
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005841
VERSION     KCWK01005841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21994:8071"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71579.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       391..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          148 c          137 g           92 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctatgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaaa tatgtccact ggtaccagca gaagccagcg caggcccctg tgttggtcat
      241 ctatgctgat agcagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gagcaccgcc accctgacca tcagcggggt cgaggccggg tatgaggctg actatttctg
      361 tcaggtgtgg gacgatagta gtgatcatcc ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005842             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:17072:13176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005842
VERSION     KCWK01005842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17072:13176"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71580.1"
                     /translation="DYYCSSYAGRNTHWLF"
     J_segment       410..440
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           88 a          161 c          120 g          109 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caactacacc caggcaaagc
      241 ccccaaactc atgatttatg atgtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctgacaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 gactgattat tactgcagct catatgcagg ccgcaacact cattggcttt tcggcggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005843             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:24114:5258
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005843
VERSION     KCWK01005843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:24114:5258"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71581.1"
                     /translation="VYYCGAWDSSLSGYIF"
     J_segment       410..447
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           93 a          157 c          125 g          110 t
ORIGIN      
        1 acatgggggc tctgcctcag ctgtgagcac agaaggcagg acttgggaca atcttcatca
       61 tgacctggtc ccctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtcta cggccccagg gcagaaggtc accatctcct
      181 gctctggaag tagctccaac atcgggagaa attctgtatc ctggtaccag caggtcccag
      241 gaacggcccc caaagtcctc atctatgaca ataataagcg cccctcgggg gtttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctggc catcactgga ctccaggctg
      361 gagatgaggc tgtttattac tgcggagcat gggatagcag tctgagtggt tacatcttcg
      421 gtgatgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt
      481 tcccg
//
LOCUS       KCWK01005844             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:7765:17561
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005844
VERSION     KCWK01005844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:7765:17561"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..266
                     /note="immunoglobulin light chain variable region"
     V_region        3..266
     V_segment       3..229
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71582.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       230..266
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           66 a           96 c           74 g           68 t
ORIGIN      
        1 acatggggtt gcctaccaca tacactggta ccagcagaag ccagggagtc ccccccggta
       61 tcttctgagt tacgaatcag actcagataa gggccagggc tctggagtcc ccagccgctt
      121 ctctggatcc aaaaatgctt caacaaacac aggcatttta cacatctctg ggctccagtc
      181 tgaggatgag gctgactatt tctgtgccat tggacacagc agcggtcctt acatcttcgg
      241 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      301 cccg
//
LOCUS       KCWK01005845             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:21502:16269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005845
VERSION     KCWK01005845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21502:16269"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71583.1"
                     /translation="DYYCQVWDSSSDHWIF"
     J_segment       390..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          148 c          135 g           90 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gactctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta aatatgtgca ctggtaccag cagaggccac cgcaggcccc tgtgcaagtc
      241 atctatactg atagcagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcgcg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtgatcat tggatattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005846             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:8430:10529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005846
VERSION     KCWK01005846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8430:10529"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71584.1"
                     /translation="DYYCQVWDTSIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          147 c          129 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtga gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tatactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc ggttctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005847             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:8629:7382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005847
VERSION     KCWK01005847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:8629:7382"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71585.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           92 a          142 c          132 g           96 t
ORIGIN      
        1 ccatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga attgactcag
      121 tcattctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccaa cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtagacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005848             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:19699:10221
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005848
VERSION     KCWK01005848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19699:10221"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71586.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           94 a          155 c          124 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaac agtgtcgcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatgatga tcaacgagcc tcaagtgtct ctgaccgatt
      301 ctctggctcc aggtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agaggttaca tcttcggtga
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01005849             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:7724:11492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005849
VERSION     KCWK01005849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:7724:11492"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..441
                     /note="immunoglobulin light chain variable region"
     V_region        115..441
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71587.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>483
                     /gene="IGLC"
BASE COUNT           88 a          156 c          127 g          112 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagta
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagtc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cgtaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005850             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:10018:11045
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005850
VERSION     KCWK01005850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10018:11045"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..378
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71588.1"
                     /translation="DYSCQVWDSESDYYIF"
     J_segment       379..416
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           89 a          142 c          129 g           94 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacccttc tcctcctcgg
       61 cctcctcgct cactgcacag gctctgcgac ctcctttgag ctgactcagc caccctcggt
      121 gtcagcggcc tcaggacaga cggccaggat cacctgtggg ggagacaaca ttggaattaa
      181 atttgtccac tggtaccagc agaagccagc gcaggcccct gtgaaggtca tctatgctga
      241 tgacaaacgg ccctcaggga tccctgagag attctctggc tccaattcag ggaacaccgc
      301 caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattcct gtcaggtgtg
      361 ggatagtgag agtgattatt acatcttcgg tgctgggacc cggctcaccg tcctaggtca
      421 gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005851             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:16016:5605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005851
VERSION     KCWK01005851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:16016:5605"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..434
                     /note="immunoglobulin light chain variable region"
     V_region        88..434
     V_segment       88..397
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71589.1"
                     /translation="DYYCSIGHSSGLYIF"
     J_segment       399..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>474
                     /gene="IGLC"
BASE COUNT           89 a          158 c          115 g          112 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcatctcctg gagcatcagc cagtctcaca tgcaccttca ccggtggcat caatgttgct
      181 gtctaccaca tacactggta ccagcagaag ccagggagtc ccccccggtt tcttctgagg
      241 tacaaatcag actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      301 agtaatgctt cagcgaacac agggatttta cgcatttctg ggctccagtc tgaggatgag
      361 gctgactatt actgttccat tggacacagc agcggtcttt acatcttcgg tgctgggacc
      421 cggctcaccg tcctgggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005852             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:9286:11499
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005852
VERSION     KCWK01005852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:9286:11499"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71590.1"
                     /translation="DYYCAMWHSSASYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           91 a          162 c          113 g          114 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcatcaat
      181 gttgctagtt acagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
      241 ctttactact actcagactc aagtaaccac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgtttcggc caatgcaggg cttttactga tctctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccatgtgg cacagcagcg cttcttacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005853             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:9532:6170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005853
VERSION     KCWK01005853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9532:6170"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71591.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           90 a          147 c          128 g           96 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtcaaag tgtgcactgg taccagcaca agccaccgca ggcccctgtt ctggtcatct
      241 tttattatac cgaacggccc tcaggaatcc ctgagcgaat ctctggctcc aaatcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cacaagtctt gatcacggct tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005854             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:18133:8138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005854
VERSION     KCWK01005854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18133:8138"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71592.1"
                     /translation="DYYCSSYAGRNSFLF"
     J_segment       400..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          154 c          125 g          111 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctgggaccag
      181 cagtgatgtt gggtattctc atgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 caaactcatg atttatgatg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg gtccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag gaactctttc ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005855             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:15834:8221
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005855
VERSION     KCWK01005855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:15834:8221"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..264
                     /note="immunoglobulin light chain variable region"
     V_region        6..264
     V_segment       6..226
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <189..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71593.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       228..264
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>302
                     /gene="IGLC"
BASE COUNT           66 a           91 c           85 g           60 t
ORIGIN      
        1 acatgggggg agacaacatt ggaagtcaaa gtgtgcactg gtaccagcac aagccaccgc
       61 aggcccctgt tctggtcatc ttttattata ccgaacggcc ctcaggaatc cctgagcgaa
      121 tctctggctc caaatcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg
      181 atgaggctga ctattactgt caggtgtggg acacaagtct tgatcacggc ttattcggag
      241 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      301 cg
//
LOCUS       KCWK01005856             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:22896:6129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005856
VERSION     KCWK01005856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22896:6129"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..394
                     /gene="IGLV2-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71594.1"
                     /translation="DYYCSSYEASDTWVF"
     J_segment       395..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           83 a          155 c          123 g          107 t
ORIGIN      
        1 acatgggggg ggtctcggca gcgctctctg gacgtctcca ccatggcctg ggctctgctc
       61 ctcctcaccc tcctcactca gggcacaggg tcctgggctc agtctgcccc gattcagtct
      121 ccctctgtgt ctgggtctct tggacagtcg gtcaccatct cctgcactgg aaccagcagt
      181 gacattgggc gttataacta tgtctcctgg taccgacagc agccaggcat gaccaccaaa
      241 ctcatgatgt acaaagtcaa tatgcggccc tcaggggtct ctgatcgctt ctctggctcc
      301 aagtctggca acacggcctc cctgaccatc tctggactcc aggctgaaga cgaggctgat
      361 tattactgta gctcatatga ggccagcgac acttgggtat tcggcggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005857             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:15081:16518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005857
VERSION     KCWK01005857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15081:16518"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71595.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          153 c          121 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005858             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:7123:5719
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005858
VERSION     KCWK01005858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7123:5719"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71596.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       413..449
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           96 a          158 c          122 g          111 t
ORIGIN      
        1 acatggggaa gcgcagcctc agctgtgggt acagaaggca ggactcagga caatctccag
       61 catggcctgg ttccctctcc tcctcaccct cctcactcac tgtgcagggt cctgggccca
      121 gtctgtgttg actcagcctc cctcagcgtc tgaggccgcc gggaagagtg tcaccatctc
      181 ctgttctgga agcagctcca acatcggaag taatagtgta tcctggtacc aacaactccc
      241 agaaacggct cccaaactcc tcatgtatta taatcatcgg cgagcctcag gtgtctctga
      301 ccgattctct ggctccaagt ctggcacttc agcctccctg gccatcagtg ggctccagac
      361 cgaggatgag gctgattatt actgcgcagt ttgggatgat agcctgaccg gttacatctt
      421 cggtactggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      481 gttcccg
//
LOCUS       KCWK01005859             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:5688:11636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005859
VERSION     KCWK01005859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5688:11636"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71597.1"
                     /translation="DYYCCSHAGSDIFVLF"
     J_segment       404..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           86 a          158 c          126 g          108 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggcggtt ataactatgt ctcctggtac caacaacatc cagacacagc
      241 ccccaaactc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgctgct cacatgcagg cagtgatatt ttcgtgttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005860             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:22378:16938
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005860
VERSION     KCWK01005860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22378:16938"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71598.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          156 c          118 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgactacca catacactgg taccagcaga agtcagggag tcctccccgg tatcttctaa
      241 gatacaaatc agactcagat cagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acggggattt tacacgtctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtga ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005861             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:12021:21985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005861
VERSION     KCWK01005861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12021:21985"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..350
                     /note="immunoglobulin light chain variable region"
     V_region        8..350
     V_segment       8..313
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <278..>322
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71599.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       316..350
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        351..>388
                     /gene="IGLC"
BASE COUNT           81 a          121 c          101 g           85 t
ORIGIN      
        1 acatggggtg ctgactcagc caccctccct gtctgcatcc ccgggagcat cggccagact
       61 cccctgcacc ctgagcagtg acctcagtgt tggtagtaaa aacatgtact ggtaccaaca
      121 gaagccaggg agcgctccca ggttattcct gtactactac tccgactcag acaagcagct
      181 gggacctggg gtccccaatc gagtctctgg ctccaaggag acctcaagta acacagcgtt
      241 tttgctcatc tctgggctcc agcctgagga cgaggccgat tattactgtc aggtgtatga
      301 cagtagtgct aatgtcttat tcggaggagg gacccggctg accgtcctag gtcagcccaa
      361 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005862             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:14972:18430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005862
VERSION     KCWK01005862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14972:18430"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71600.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       406..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           90 a          153 c          127 g          111 t
ORIGIN      
        1 acatgggggg cttcagctgt gggcacagga agcagcactc aggacagtct ccagcatggc
       61 ctggtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag tgtctggggc gcccgggcag agggtcacca tctcctgcac
      181 tgggagcagc tccaacattg gaggttatta tgtgcagtgg taccagcagc ttccaggaac
      241 ggcccccaaa ctcctcatct atgaaaatga taaacgaccc tcaggggttt ctgatcgatt
      301 ctctggctcc cagtctgatt cctcagcctc cctgaccatc actggactcc agtctgagga
      361 tgaggctgat tattactgcc agtcctatga cagcagcttg agtgttgtgt tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01005863             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:15027:18252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005863
VERSION     KCWK01005863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:15027:18252"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71601.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          147 c          128 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggttcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005864             393 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:15253:21042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005864
VERSION     KCWK01005864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 393)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:15253:21042"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..355
                     /note="immunoglobulin light chain variable region"
     V_region        8..355
     V_segment       8..316
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <283..>327
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71602.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       318..355
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        356..>393
                     /gene="IGLC"
BASE COUNT           82 a          119 c           98 g           94 t
ORIGIN      
        1 acatgggagc ctgtgctgac tcagccaacc tccctctcag cttctcctgg agcatcagcc
       61 agactcacct gcaccttgag cagtggcatc agtgttggta cttacaggat attctggtac
      121 cagcagaggc cagggagtcc tccccggtat cttctgaacc accacacaga ctcagataaa
      181 catcagggct ctggagtccc cagccgcttc tctggatcca aagatgcttc ggccaatgca
      241 gggattttgc tcatctctgg gctccagtct gaggatgagg ctgactatta ctgtatgatt
      301 tggcacaaca atgcttatgt gttattcgga ggagggaccc ggctgaccgt cctaggtcag
      361 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005865             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:10973:11351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005865
VERSION     KCWK01005865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10973:11351"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71603.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       400..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           81 a          164 c          115 g          113 t
ORIGIN      
        1 acatgggggg gggtctcaga aggcagcgct ctcaggacgt ctccaccatg gcctggactc
       61 tgctcctcgt caccctcctc actcaaggca caggatcctg ggctcagtct gccccgactc
      121 agcctccctc tgtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacgt tggtggttct aactctgtct cctggtacca acaacaccca ggcagagccc
      241 ccaaactcat gatttttggt gtcaataatc ggccctctgg ggtctctgac cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg cctccagtct gaggacgagg
      361 ctgattatta ctgttgttca cattcaacca gtagcactta cgtcttcggt cctgggaccc
      421 ggctcaccgt cctgggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005866             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:11891:9115
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005866
VERSION     KCWK01005866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11891:9115"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..388
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71604.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       389..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           90 a          141 c          127 g          100 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagagctct ggggtgtctc caccatggcc tggactcctc
       61 tctggctcac cctcctcagt ctttgcacag gttctatggt ttcttctgag ctgactcagg
      121 accctgcagt gtctgtggcc ttggggcaga cagtcaggat tacctgccaa ggagacagcc
      181 tcagaagttc ttatgcaaac tggtaccaac agaggccagg ccaggcccct gtgctggtcg
      241 tctatggtaa caactaccgg ccctcaggga tcccagaacg attctctggc tcctcctccc
      301 gaaacacagc ttccttgacc atcactgggg ctcaggtgga agatgaggct gactattact
      361 gtgactcctg ggacagcagg ggaacccaat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005867             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:15717:13567
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005867
VERSION     KCWK01005867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15717:13567"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..419
                     /note="immunoglobulin light chain variable region"
     V_region        89..419
     V_segment       89..380
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71605.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       382..419
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           86 a          144 c          117 g          110 t
ORIGIN      
        1 acatggggca gcactcagga cagtctccag catggcctgg tctcctctcc tcctcaccct
       61 tctcattcac tgcacagggt cctgggccca gtctgtgctg acgcagccgc cctcagtgtc
      121 tggggcgccc gggcagaggg tcagtatttc ttgcactggg agcagctcca acattggagg
      181 ttattatgtg cagtggtacc agcagcttcc aggaacggcc cccaaactcc tcatctatga
      241 aaatgataaa cgaccctcag ggatttctga tcgattctct ggctcccagt ctgattcctc
      301 agcctccctg accatcactg gactccagtc tgaggatgag gctgattatt actgccagtc
      361 ctatgacagc agcttgagtg ttgtgttatt cggaggaggg acccggctga ccgtcctagg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005868             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:12869:12756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005868
VERSION     KCWK01005868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12869:12756"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71606.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          140 c          138 g           99 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 gcaccctcga tttcagtgtc ccccggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atgtatgctg atagcgagcg gccctcaggg atccctgggc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacatgaa tagtcatcat ctattattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005869             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:18185:15748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005869
VERSION     KCWK01005869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18185:15748"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..399
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71607.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       400..436
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           90 a          153 c          121 g          110 t
ORIGIN      
        1 acatgggggg cacaggaggc agcactcagg acagtctcca gcatggcctg gtctcctctc
       61 ctcctcaccc ttctcattca cttcacagtt ccagggtcct gggcccagtc tgtgctgacg
      121 cagccgccct cagtgtctgg ggcgcccggg cagagggtca ccatctcctg cactgggagc
      181 agctccaaca ttggagatta ttttgtgcag tggtaccagc accttccagg aacggccccc
      241 aaactcctca tctatgaaaa taataagcgg ccctcaggga tttctgatcg attctctggc
      301 tcccagtctg gaacctcagc ctccctgacc atcactggac tccagtctga ggatgaggct
      361 gattattact gccagtccta tgacagcagt ttgattgctg tgttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005870             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:6821:13617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005870
VERSION     KCWK01005870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6821:13617"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71608.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          163 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca aacagcgggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005871             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:18818:14615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005871
VERSION     KCWK01005871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:18818:14615"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71609.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          163 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca accagcgggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005872             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:8730:3527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005872
VERSION     KCWK01005872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:8730:3527"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71610.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          141 c          138 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcggcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005873             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20276:12907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005873
VERSION     KCWK01005873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20276:12907"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71611.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          148 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctc tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005874             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:19588:7142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005874
VERSION     KCWK01005874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19588:7142"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71612.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          160 c          111 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagcaaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005875             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:17591:12978
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005875
VERSION     KCWK01005875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17591:12978"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71613.1"
                     /translation="DFYCQVWDIYVDHPVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           87 a          141 c          136 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaggccaccg caggcccctg tgctggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgaggccggg gatgaggctg acttttattg
      361 tcaggtgtgg gacatttatg ttgaccatcc ggtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005876             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:7123:12813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005876
VERSION     KCWK01005876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:7123:12813"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71614.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          143 c          134 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 tcaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtcaa ctggtaccaa cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgacc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgcggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tactgatcat ccggtgttgt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005877             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:8110:13942
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005877
VERSION     KCWK01005877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8110:13942"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71615.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       410..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          163 c          123 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta cttctactcc gactcagaca agcagctggg acctggggtc cccgatcgcg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtc ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005878             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:14484:10284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005878
VERSION     KCWK01005878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14484:10284"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71616.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          161 c          119 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgtatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctata ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005879             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:11117:10306
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005879
VERSION     KCWK01005879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:11117:10306"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71617.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       401..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          151 c          115 g          115 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcatctcc tggagcatca gccagactca cctgcacctt gaacagtggc atcagtgttg
      181 gtaattacag gatattctgg taccaccaga agccagggag tcctccccgg tatcttctga
      241 attaccacag agactcagat attcaccagg gctctggagt ccccagccgc ttctctgggt
      301 ccaaggatgc ttcggccaat gcagggattt tactcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtatg atttggcaca acaatgctta ttgggtattc ggcggaggga
      421 cccggctaac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005880             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:11223:14332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005880
VERSION     KCWK01005880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11223:14332"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71618.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           94 a          145 c          131 g           92 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggcgctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacaac
      181 attggaacta aaactgtgca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atactaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg actaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005881             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20156:5149
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005881
VERSION     KCWK01005881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20156:5149"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71619.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          150 c          122 g          115 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcagga cacaggatcc tgggttcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat gttgggtatt ataacgctgt gtcttggtac caacagcatc caggcaaagc
      241 ccccaaactc atgatttatg acgtcattaa gcggccctca ggggtttctg atcgcttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagaaataat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgtcccctcg gtcactctct tcccg
//
LOCUS       KCWK01005882             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:8954:7987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005882
VERSION     KCWK01005882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8954:7987"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71620.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       411..447
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          159 c          127 g          109 t
ORIGIN      
        1 acatgggggc gcagcttcag ctgtgggtac agaaggcagg actcaggaca atctccagca
       61 tggcctggtt ccctctcgtc ctcaccctcc tcactcactg tgcagggtcc tgggcccagt
      121 ctgtgctgac tcagcctccc tcagcgtctg aggccgccag gaagagtgtc tccatctcct
      181 gttctggaag cagctccaac atcggaagtc atagtgtctc ctggtaccag cagctcccag
      241 gaacagctcc caaactcctc atctattata gtgatcaacg agcctcaggt gtctctgacc
      301 gattctctgg ctccaagtct ggcacgtcag cctccctggc catcagtggg ctccagaccg
      361 aggatgaggc tgattattac tgcgcggcat gggatgatag cctgagcggt tacatcttcg
      421 gtgctgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt
      481 tcccg
//
LOCUS       KCWK01005883             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:19531:8071
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005883
VERSION     KCWK01005883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19531:8071"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71621.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       414..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          157 c          127 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggagatt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctctgaaa atcataagcg accctcaggg gtttctgatc
      301 gcttctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagtag tttgagtgct gtattattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005884             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:24206:11259
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005884
VERSION     KCWK01005884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:24206:11259"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..453
                     /note="immunoglobulin light chain variable region"
     V_region        123..453
     V_segment       123..416
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71622.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       417..453
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           91 a          158 c          126 g          116 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactt cacagttcca gggtcctggg
      121 cccagtctgt gctgacgcag ccgccctcag tgtctggggc gcccgggcag agggtcacca
      181 tctcctgcac tgggagcagc tccaacattg gagattattt tgtgcagtgg taccagcacc
      241 ttccaggaac ggcccccaaa ctcctcatct atgaaaataa taagcggccc tcagggattt
      301 ctgatcgatt ctctggctcc cagtctggaa cctcagcctc cctgaccatc actggactcc
      361 agtctgagga tgaggctgat tattactgcc agtcctatga cagcagtttg attgctgtgt
      421 tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      481 ctctcttccc g
//
LOCUS       KCWK01005885             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:21210:4849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005885
VERSION     KCWK01005885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21210:4849"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71623.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           88 a          144 c          137 g           92 t
ORIGIN      
        1 acatgggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgcggggga gacaagattg
      181 gaagtgaagt tgtgaactgg taccagcaga agccagcgca cgcccctgtg ctggtcatct
      241 atgctaatag cgaacggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acacggccac cctgaccatc agcggggtcg aggccggggg tgaggctgac tattactgtc
      361 aggtgtggga catgcgtagt gatcaaccgc tattcggcgg agggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005886             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:18451:20633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005886
VERSION     KCWK01005886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18451:20633"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71624.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          160 c          117 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctctgcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccatatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatataa atcagactca gataaggacc agggctctgg ggtccccagc cgcttctctg
      301 gatccaaaga tgcctcagcg aacacggggc ttttgcgcat ctctggactc cagtctgagg
      361 atgaggctga ctactactgt gccattggac acagcagcgg tgattacatc ttcggtgctg
      421 ggacccgcct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005887             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:9574:13519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005887
VERSION     KCWK01005887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:9574:13519"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..306
                     /note="immunoglobulin light chain variable region"
     V_region        9..306
     V_segment       9..262
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71625.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       276..306
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           71 a          103 c           88 g           82 t
ORIGIN      
        1 acatgggcgg gtctcctgga cagtcggtca ccatctcctg cactggaacc agcagtgata
       61 ttgggtatta tcatgctgtg tcttggtacc agcatcatcc aggcaaagcc cccaaactca
      121 tgatttatga ggtcaataaa cggcccgcag gggtctctga tcgcttctct ggctccaagt
      181 ctggcaacac ggcctccctg accatctctg ggctccagac tgaggatgag gctgattatt
      241 actgtagctc atatgcaggc agcaacagtt tattcttcgg aggagggacc cggctgaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005888             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:22029:20983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005888
VERSION     KCWK01005888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:22029:20983"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71626.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          105 a          136 c          122 g          100 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatactcagt ggttccagca gcagccaggc caggcccctt tcctggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgggcga ttctctagct ccagttcagg
      301 gacaacaatt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagta gacagcagtg gaaatcttcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005889             295 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:6157:17959
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005889
VERSION     KCWK01005889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 295)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6157:17959"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..257
                     /note="immunoglobulin light chain variable region"
     V_region        8..257
     V_segment       8..220
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <182..>229
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71627.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       221..257
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>295
                     /gene="IGLC"
BASE COUNT           62 a           90 c           75 g           68 t
ORIGIN      
        1 acatgggaac atcggaagta ataatgtgtc ctggtaccag cacctcccag gaacagctcc
       61 caaactcctc atctattata atgatcaacg aggctcaggt gtctctgacc gattctctgg
      121 ctccaagtct ggcacgtcag cctccctggc catcagtggg ctccggaccg aggatgaggc
      181 tgattattac tgcgcagcgt gggatgatag gttgagcagt tacatcttcg ctgctgggac
      241 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005890             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:21656:7098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005890
VERSION     KCWK01005890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:21656:7098"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..254
                     /note="immunoglobulin light chain variable region"
     V_region        9..254
     V_segment       9..217
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71628.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       218..254
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           62 a           85 c           81 g           64 t
ORIGIN      
        1 acatgggatt ggaattaaat ttgtccactg gtaccagcag aagccagcgc aggcccctgt
       61 gaaggtcatc tatgctgatg acaaacggcc ctcagggatc cctgagagat tctctggctc
      121 caattcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga
      181 ctattcctgt caggtgtggg acagtgagac tgattattac atcttcggtt ctgggacccg
      241 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01005891             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:9970:6899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005891
VERSION     KCWK01005891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9970:6899"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71629.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          159 c          112 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccaacca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005892             366 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:19444:17069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005892
VERSION     KCWK01005892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 366)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19444:17069"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..328
                     /note="immunoglobulin light chain variable region"
     V_region        8..328
     V_segment       8..291
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <253..>300
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71630.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       293..328
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        329..>366
                     /gene="IGLC"
BASE COUNT           76 a          106 c          110 g           74 t
ORIGIN      
        1 acatgggatg atctgactca gccaccctcg atttcagtgt ccccaggaca gacggccagg
       61 gtcacctgtg ggggagacaa catcggaggt gaagttgtga attggtacca gcagaagcca
      121 ccgcaggccc ctgtgttggt catctatgct gatagcgagc ggccctcagg gatcccggag
      181 cgattctctg gctccaaatc agggaacacg gccaccctga ccatcagcgg ggtcgaggcc
      241 ggagatgagg ctgactatta ctgtcaggtg tgggacctta atagtcatca tctgttattc
      301 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      361 ttcccg
//
LOCUS       KCWK01005893             273 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:11840:12761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005893
VERSION     KCWK01005893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 273)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 273)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11840:12761"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..235
                     /note="immunoglobulin light chain variable region"
     V_region        116..235
     V_segment       116..199
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <163..>207
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71631.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       200..235
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        236..>273
                     /gene="IGLC"
BASE COUNT           47 a           95 c           69 g           62 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaagctg ccccgactca
      121 gcctccctga ccatctctgg gctccaggct gaggatgagg ctgattatta ctgctgctca
      181 tatgtaggca gcaacactta catcttcgat gttgggaccc ggctcaccgt cctaggtcag
      241 cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005894             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:14157:20220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005894
VERSION     KCWK01005894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14157:20220"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..409
                     /note="immunoglobulin light chain variable region"
     V_region        79..409
     V_segment       79..370
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <334..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71632.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       375..409
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           83 a          143 c          114 g          107 t
ORIGIN      
        1 acatggggga cagtctccag catggcctgg tctcctctcc tcctcaccct tctcattcac
       61 tgcacagggt cctgggccca gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc
      121 gggcagaggg tcacgatctc ctgcagtggg agcaactcca acattggata ttattatgtg
      181 cagtggtacc agcagcttcc aggaacggcc cccaaactcc tcatctatga aaataataag
      241 cgaccctctg gggtttctga tcgattctct ggctcccagt ctggtacctc agcctccctg
      301 accatcactg gactccagtc tgaggatgag gctgattatt actgccactc ctatgacagc
      361 agtttgagtg gtgtcttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005895             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:15154:4299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005895
VERSION     KCWK01005895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15154:4299"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..436
                     /note="immunoglobulin light chain variable region"
     V_region        111..436
     V_segment       111..401
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71633.1"
                     /translation="DYYCQSADGNYRVF"
     J_segment       402..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>475
                     /gene="IGLC"
BASE COUNT           86 a          164 c          123 g          102 t
ORIGIN      
        1 acatggggct ggctgtgact cagaaagcag agcctggggc gtctccacca tggcctgggc
       61 tccactcctc ctcaccctcc tcgctcactg cacagggtct tgggctgaac ttgtgttcac
      121 tcagccccat tctgtgtcgg ggtctccggg gcagacggtc accatctcct gcacccgcag
      181 cattggcaac attgacagtg aatatgtgca gtggtaccag cagcgcccgg gcagtgcccc
      241 caccacactg atttacaaag atagtcaaag accctctggg gtccctgacc ggttctctgg
      301 ctccatcgac agctcctcca actctgcctc cctcgccatc tctgggctac agtctgagga
      361 cgaggctgac tactactgtc agtctgctga tggcaactac agggtcttcg gcggagggac
      421 ccggctaacc gtcctaagtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005896             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:4801:19434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005896
VERSION     KCWK01005896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4801:19434"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..309
                     /note="immunoglobulin light chain variable region"
     V_region        8..309
     V_segment       8..277
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <240..>281
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71634.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       278..309
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        310..>347
                     /gene="IGLC"
BASE COUNT           72 a          107 c          100 g           68 t
ORIGIN      
        1 acatggggga ccctgccgtg tctgtggcct tgggacagac agtcaggatt acctgccaag
       61 gagacagcct cagaagctct tatgcaagct ggtaccagca gaggccaggc caggcccctg
      121 tgctggtcgt ctatggtaac aactaccggc cctcagggat cccagagcga ttctctggct
      181 cctactcacg aaacacagct tccttgacca tctctggggc tcaggtggaa gatgaggctg
      241 actattactg tgactcctgg gacagcagcg gaacccaatt cggaggaggg acccggctga
      301 ccgtcctagg tcagcccaag ggtgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005897             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:17103:4667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005897
VERSION     KCWK01005897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17103:4667"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71635.1"
                     /translation="DYYCSTYVGSNTYMF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          159 c          122 g          107 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgcgtatg ataatgctgt gtcttggtac cagcagcatc caggcaaggc
      241 ccccaaactc atgatttatg acgtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 gggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgactat tactgcagca catatgtagg cagcaacact tacatgttcg atcctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005898             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:7245:15444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005898
VERSION     KCWK01005898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:7245:15444"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71636.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          156 c          123 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag ccaaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005899             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:5075:11374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005899
VERSION     KCWK01005899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5075:11374"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..450
                     /note="immunoglobulin light chain variable region"
     V_region        117..450
     V_segment       117..413
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71637.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       416..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           89 a          161 c          132 g          106 t
ORIGIN      
        1 acatgggggg gctcattcct ggctgtggct caggaagcag agcctggagc gtctccacca
       61 tggcctgggc tccactcctc ctcaccctcc tcgctcactg cacagggtct tgggctgagg
      121 ttctgttcac gcagccccat tctgtgtcgg ggtctccggg gcagacggtc accatctcct
      181 gtacccgcag cagaggcaac attgacaata gttatgtgca gtggtaccag cagcgcccgg
      241 gcagtgcccc gaccacagtg atttacagag ataaccaaag agcctctggg gtccctgatc
      301 ggttctctgg ctccatcgac agctcctcca actctgcctc cctcaccatc tctgggctga
      361 agtctgagga cgaggctgac tactactgtc agtctactga tggcaactac aatcggttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01005900             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:14889:18982
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005900
VERSION     KCWK01005900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14889:18982"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..249
                     /note="immunoglobulin light chain variable region"
     V_region        8..249
     V_segment       8..210
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <180..>221
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71638.1"
                     /translation="DYYCQMYDSSDVLF"
     J_segment       216..249
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        250..>287
                     /gene="IGLC"
BASE COUNT           61 a           84 c           78 g           64 t
ORIGIN      
        1 acatggggta ctggtaccag cagaagccag ggagcgctcc caggttattc ctgtactact
       61 actccgactc agacaagcaa ctgggacctg gggtccccaa tcgagtctct ggctccaagg
      121 agacctcagg taacacagcg tttttgctca tctctgggct ccagcctgag gacgaggccg
      181 attattactg tcagatgtat gacagtagtg atgtattatt cggaggaggg acccggctga
      241 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005901             338 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:17405:17707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005901
VERSION     KCWK01005901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 338)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17405:17707"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..300
                     /note="immunoglobulin light chain variable region"
     V_region        87..300
     V_segment       87..263
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <228..>272
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71639.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       264..300
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        301..>338
                     /gene="IGLC"
BASE COUNT           61 a          106 c           96 g           75 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacaga agccaggcca gtcccctgta ttggtcatct
      121 ctgaggacac cgaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      181 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      241 actcagcaga cagtagtggt catggcttct tcggaggagg gacccggctg accgtcctag
      301 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005902             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:7240:10557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005902
VERSION     KCWK01005902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7240:10557"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71640.1"
                     /translation="DYYCQVWDSSSRYAVF"
     J_segment       396..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          149 c          136 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca gcaggctctg cgacctccta tgagctgact
      121 cagccaccct cattgccagc ggcctcagga cagacggcca ggatcgcctg tgggggagac
      181 atcattggag gtgaaaatgt cttctggtac cagcagaagc caccgcaggc ccctgtcctg
      241 gtcatctatg gtgatacgaa acggccctca gggatccctg agcgattctc tggctccatc
      301 tctgggaaca ccgccaccct gaccatcaac agggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtagtaga tacgcggtat tcggcggagg gacccggcta
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005903             294 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:21312:17867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005903
VERSION     KCWK01005903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 294)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21312:17867"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..256
                     /note="immunoglobulin light chain variable region"
     V_region        8..256
     V_segment       8..216
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <184..>228
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71641.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       219..256
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        257..>294
                     /gene="IGLC"
BASE COUNT           62 a           88 c           80 g           64 t
ORIGIN      
        1 acatgggaca tacactggta ccagcagaag ccagggagtc ctccccggta tcttctgaga
       61 tacaaatcgg actcagataa gggccagggc tctggagtcc ccagccgctt ctctggatcc
      121 aaagatgctt cagcgaacgc agggatttta cgcatctctg ggctccagtc tgaggatgag
      181 gctgactatt actgtgccat tgggcacagc agcggtgatt acatcttcgg tgctgggacc
      241 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01005904             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:13072:20048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005904
VERSION     KCWK01005904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:13072:20048"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71642.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          105 a          137 c          122 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtctgtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005905             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:14502:16277
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005905
VERSION     KCWK01005905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14502:16277"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..424
                     /note="immunoglobulin light chain variable region"
     V_region        106..424
     V_segment       106..392
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71643.1"
                     /translation="DYYCDSWDSSGAQF"
     J_segment       393..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           91 a          143 c          128 g          100 t
ORIGIN      
        1 acatggggag ctgtgggctc agaagcagag ctctggggtg tctccaccat ggcctggact
       61 cctctctggc tcaccctcct cagtctttgc acaggttcta tggtttcttc tgagctgact
      121 caggaccctg cagtgtctgt ggccttgggg cagacagtca ggattacctg ccaaggagac
      181 agcctcagaa gctcttatgc aaactggtac caacagaggc caggccaggc ccctgtgctg
      241 gtcgtctatg gtaacaacta ccggccctca gggatcccag agcgattctc tggctcctac
      301 tcccgaaaca cagcttcctt gaccatcact gggactcagg tggaagatga ggctgactat
      361 tactgtgact cctgggacag cagcggagcc caattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005906             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:8045:10315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005906
VERSION     KCWK01005906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8045:10315"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..418
                     /note="immunoglobulin light chain variable region"
     V_region        88..418
     V_segment       88..381
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <343..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71644.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       382..418
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>456
                     /gene="IGLC"
BASE COUNT           87 a          150 c          117 g          102 t
ORIGIN      
        1 acatggggag gactcaggac aatctccagc atggcctggt tccctctcgt cctcaccctc
       61 ctcactcact gtgcagggtc ctgggcccag tctgtgctga ctcagcctcc ctccgcgtct
      121 gaggccgcca ggaagagtgt caccatctcc tgttctggaa gcagctccaa catcggaagg
      181 aatagtgtat cctggtacca gcagctccca ggaacagctc ccaaactcct catctattat
      241 agtgatcaac gagcctcagg tgtctctgac cgattctctg gctccaagtc tggcatgtca
      301 gcctccctgg ccatcagcgg gctccagacc gaggatgagg gtgattatta ctgcgcagca
      361 tgggatgata gcctgagcgg ttacatcttc ggtgctggga cccggctcac cgtcctaggt
      421 cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005907             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:22557:14173
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005907
VERSION     KCWK01005907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22557:14173"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..414
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <378..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71645.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       415..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           86 a          159 c          134 g          109 t
ORIGIN      
        1 acatgggggc agagtacatg gggtggggtc tcaggaggca gcgctctcgg gacgtctcca
       61 ccatggcctg ggctctgctc ctcctcaccc tcctcactca gggcacagga tcctgggctc
      121 agtctgccct gactcagcct ccctcagtgt ccaagtctct tggacagtcg gtcaccatct
      181 cctgcactgg aaccagcagt gacattggtg gttatgatgg cgtctcctgg taccagcagc
      241 actcagggac agcccccaga ctcctgattt atgatgtcac taagcggccc tcaggggtct
      301 cggatcgctt ctctggctcc aagtctggca acacggcctc cctcaccatc tctgggctcc
      361 agactgagga cgaggctgat tattactgtt gctcatatag gagtggaaac acttggctat
      421 tcggcggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01005908             342 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:20077:3839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005908
VERSION     KCWK01005908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 342)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20077:3839"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..304
                     /note="immunoglobulin light chain variable region"
     V_region        7..304
     V_segment       7..260
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <232..>276
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71646.1"
                     /translation="AYYCCSYVGSNTYIF"
     J_segment       267..304
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        305..>342
                     /gene="IGLC"
BASE COUNT           67 a          106 c           81 g           88 t
ORIGIN      
        1 acatgggggt ctcctgggca gtcggtcacc atctcctgca ctggacccag cagtgatatt
       61 gggtcttcta atgctgtgtc ttggtatcaa caacatccag gcaaagcccc ccaactcata
      121 atttttgagg tcaataaacg gccctcaggg gtctctgatc gcttctctgc ttccaagtct
      181 ggcaacacgg cctccctgac catttctggg ctccaggctg aggatgaggc tgcttattac
      241 tgctgctcat atgtaggcag caacacttac atcttcgatg ttgggacccg gctcaccgtc
      301 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01005909             451 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:18783:17548
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005909
VERSION     KCWK01005909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 451)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18783:17548"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    127..413
                     /note="immunoglobulin light chain variable region"
     V_region        127..413
     V_segment       127..375
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71647.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       379..413
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>451
                     /gene="IGLC"
BASE COUNT           85 a          147 c          115 g          104 t
ORIGIN      
        1 acatggggtg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcct
      121 ccctgtctgc accctgagca ctgacctcag tgttggtggt aaaaacatgt actggtacca
      181 gcagaagcca ggaagcgctc ccaggttatt gctgtattac cactccgact cagacaagca
      241 gctgggacct ggggtcccca atcgagtctc tggctccaag gagacctcaa gtaacacagc
      301 gtttttgctc atctctgggc tccagcctga ggacgaggcc gattattact gtcaggtgta
      361 tgacagtagt gccaacacgt tattcggagg agggacccgg ctgaccgtcc taggtcagcc
      421 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005910             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:15837:9130
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005910
VERSION     KCWK01005910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15837:9130"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71648.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          155 c          129 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccag cagcttccag
      241 gagcggcccc caaactcctc atctatgaaa atgataaacg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct gattcctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cttgagtgtt gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005911             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:16799:4491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005911
VERSION     KCWK01005911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16799:4491"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71649.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       416..450
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           92 a          153 c          128 g          115 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcacgatct
      181 cctgcagtgg gagcaactcc aacattggat attattatgt gcagtggtac cagcagcttc
      241 caggaacggc ccccaaactc ctcatctatg aaaataataa gcgaccctct ggggtttctg
      301 atcgattctc tggctcccag tctggtacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccact cctatgacag cagtttgagt ggtgtcttat
      421 ttggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01005912             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:15001:9266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005912
VERSION     KCWK01005912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15001:9266"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71650.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          100 a          136 c          123 g          104 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagg tgacacagtc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagcaattct
      181 ggcaaataat tatgctcagt ggttccagca gaagccagac caggcccctg tgttggtgat
      241 atataaagac actgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacagtt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagtt gacagcagtg cccatcatcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005913             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:25350:14982
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005913
VERSION     KCWK01005913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:25350:14982"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71651.1"
                     /translation="DYFCAAWDDSLTGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          154 c          114 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc agggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaac cagctccaac
      181 atcggaagta atagtgtatc ctggtaccag cagctcccag aaacgtctcc caaactcctc
      241 atctattata atgatcggcg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattatttc
      361 tgcgcagcat gggatgatag cctgaccggt tacattttcg gtactgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005914             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:20964:5219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005914
VERSION     KCWK01005914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20964:5219"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..401
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71652.1"
                     /translation="DYYCASYEGSNTFLF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          158 c          121 g          106 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc agtggaacca
      181 gcagtaagat tgggtatcac aatgctgtgt cctggtacca agagcatcca ggcaaagccc
      241 ccaaactcat gatttatgac gtcaataagc ggccctcagg gatctctgat cgcttctctg
      301 gctccaagtc tggcgacacg gcctccctga ccatctctgg gctccagcct gatgatgagg
      361 gtgattatta ctgcgcctca tatgaaggca gcaacacttt cctcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005915             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:4890:6826
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005915
VERSION     KCWK01005915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:4890:6826"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71653.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          157 c          127 g          111 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtta catcttcggt
      421 gttgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005916             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:3201:9005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005916
VERSION     KCWK01005916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:3201:9005"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..266
                     /note="immunoglobulin light chain variable region"
     V_region        8..266
     V_segment       8..228
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71654.1"
                     /translation="DYYCQVWDTPIDHGLF"
     J_segment       230..266
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           66 a           92 c           86 g           60 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaagtca aagtgtgcac tggtaccagc acaagccacc
       61 gcaggcccct gtactggtca tcttttatta taccgaacgg ccctcaggaa tccctgagcg
      121 attctctggc tccaaatcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggacacacct attgatcacg gcttattcgg
      241 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      301 cccg
//
LOCUS       KCWK01005917             451 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:18201:6973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005917
VERSION     KCWK01005917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 451)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18201:6973"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..413
                     /note="immunoglobulin light chain variable region"
     V_region        92..413
     V_segment       92..377
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71655.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       381..413
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>451
                     /gene="IGLC"
BASE COUNT           92 a          139 c          128 g           92 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacccttc tcctcctcgg
       61 cctcctcgct tactgcacag gctctgcgac ctcctatgaa ttgactcagt caccctcagt
      121 gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca ttggaactaa
      181 aactgtgcac tggtaccaac agaagccacc gcagggccct gtattggtca tctttgctga
      241 tagtagacgg ccctcaggga tccctgagcg attctctggc tccaattcag ggaacaccgc
      301 caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg
      361 ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc taggtcagcc
      421 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01005918             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:12920:15927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005918
VERSION     KCWK01005918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12920:15927"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71656.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          160 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcaatgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagag gccagggagc gctcccaggt
      241 tattcctgta ttactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaggtaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005919             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:18202:4092
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005919
VERSION     KCWK01005919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18202:4092"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71657.1"
                     /translation="DYYCAAWDDSLRGYLF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          153 c          119 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaacagtgtc gccatctcct gttctggaag cagctccaac
      181 atcggaagtc atagtgtatc ctggtaccag cagctcccag gaacagctcc caaactcctc
      241 atctattatg atgatcaacg agcctcaggt gtctctgacc gattctctgg ctccaggtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggatgatag cctgagaggt tacctcttcg gtgatgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005920             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:19405:11368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005920
VERSION     KCWK01005920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19405:11368"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..399
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71658.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       400..436
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           92 a          153 c          119 g          110 t
ORIGIN      
        1 acatggggga cacaggaggc agcactcagg acagtctcca gcatggcctg gtctcctctc
       61 ctcctcaccc ttctcattca cttcacagtt ccagggtcct gggcccagtc tgtgctgacg
      121 cagccgccct cagtgtctgg ggcgcccggg cagagggtca ccatctcctg cactgggagc
      181 agctccaaca ttggagatta ttttgtgcag tggtaccagc accttccagg aacggccccc
      241 aaactcctca tctatgaaaa taataagcga ccctcaggga tttctgatcg attctctggc
      301 tcccagtctg gaacctcagc ctccctgacc atcactggac tccagtctga ggatgaggct
      361 gattattact gccagtccta tgacagcagt ttgattgctg tgttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005921             328 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:5446:15438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005921
VERSION     KCWK01005921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 328)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5446:15438"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..290
                     /note="immunoglobulin light chain variable region"
     V_region        7..290
     V_segment       7..251
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>262
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71659.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       253..290
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        291..>328
                     /gene="IGLC"
BASE COUNT           68 a           98 c           82 g           80 t
ORIGIN      
        1 acatgggagg gtcaccatct cctgcactgg gagcagctcc aacattggag gttattatgt
       61 gcagtggtac cagcagcttc caggaacggc ccccaaactc ctcatctatg aaaatgataa
      121 acgaccctca ggggtttctg atcgattctc tggctcccag tctgattcct cagcctccct
      181 gaccatcact ggactccagt ctgaggatga ggctgattat tactgccagt cctatgacag
      241 cagcttgagt gttgtgttat tcggaggagg gacccggctg accgtcctag gtcagcccaa
      301 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005922             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:23511:6812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005922
VERSION     KCWK01005922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:23511:6812"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..264
                     /note="immunoglobulin light chain variable region"
     V_region        6..264
     V_segment       6..226
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <189..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71660.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       228..264
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>302
                     /gene="IGLC"
BASE COUNT           66 a           92 c           84 g           60 t
ORIGIN      
        1 acatgggggg agacaacatt ggaagtcaaa gtgtgcactg gtaccagcac aagccaccgc
       61 aggcccctgt actggtcatc ttttattata ccgaacggcc ctcaggaatc cctgagcgat
      121 tctctggctc caaatcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg
      181 atgaggctga ctattactgt caggtgtggg acacaactat tgatcacggc ttcttcggag
      241 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      301 cg
//
LOCUS       KCWK01005923             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:14152:3170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005923
VERSION     KCWK01005923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14152:3170"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..391
                     /gene="IGLV7-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71661.1"
                     /translation="EYYCWLYSSDGHGLF"
     J_segment       399..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          155 c          120 g          103 t
ORIGIN      
        1 acatggggga gccagggatc ccttccaata ccagcaccat ggcctggact ctgctcctcc
       61 tccagttcct cctcacttgc tgcccagggt ccaattctca ggctgtagtg actcaggagc
      121 cctcactgac tgtgtcccca ggagggacag tcactctcac ctgtggttcc agtactggag
      181 cggtcaccag tggtcactat ccacactggt tccagcagaa acctggacaa gcccccaaga
      241 cactgattta tgatacaacc aacaaactct cctggacccc tgcccggttc tcaggctccc
      301 ttgctggggg taaagctgcc ctgacacttt cgggtgcgca gcccgaggac gaggctgaat
      361 attactgctg gctgtattcc agtgatggtc atggcttgtt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005924             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:19603:17633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005924
VERSION     KCWK01005924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19603:17633"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71662.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       405..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           89 a          154 c          126 g          111 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccct ctcctgcact
      181 gggagcagct ccaacattgg agattattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccaaac tcctcatcta tgaaaataat aagcgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctggtac ctcagcctcc ctgaccatca ctggactcca gtctgacgat
      361 gaggctgatt attactgtca gtcctatgat agcagcctga gtgttgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005925             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:15558:17944
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005925
VERSION     KCWK01005925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15558:17944"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71663.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          163 c          113 g          111 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaccaatg
      181 ttggtagtta caggatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacta ctcagactca actaagcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttgcatc ttcggtcctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005926             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:12079:12724
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005926
VERSION     KCWK01005926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12079:12724"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71664.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          157 c          122 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcact
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005927             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:15763:2992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005927
VERSION     KCWK01005927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15763:2992"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71665.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          108 a          136 c          122 g          100 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcacaatc ttcccg
//
LOCUS       KCWK01005928             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:16472:4137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005928
VERSION     KCWK01005928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16472:4137"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..380
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71666.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       384..416
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           94 a          141 c          128 g           91 t
ORIGIN      
        1 acatgggtca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc ttctcctcct
       61 cggcctcctc gcttactgca caggctctgc gacctcctat gaactgactc agtcaccctc
      121 agtgtcagcg gcctcaggac agccggccag gatcacctgt gggggagaca acattggaat
      181 taaaactgta cactggtacc agcagaagcc accgcagggc cctgtattgg tcatctttgc
      241 tgatagtaag cggcccacag ggatccctga gcgattctct ggctccaact cagggaacac
      301 cgccaccctg accatcagca gggtcgaggc cggggatgag gctgactatt actgtcaggt
      361 gtgggacagt agtagtaaat ggatattcgg cggggggacc cggctaaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005929             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:14658:5633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005929
VERSION     KCWK01005929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14658:5633"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71667.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           93 a          161 c          109 g          110 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggaacatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt cctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005930             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:15811:6521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005930
VERSION     KCWK01005930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15811:6521"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71668.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          148 c          129 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttattcg gaagagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005931             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:21162:5902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005931
VERSION     KCWK01005931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21162:5902"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71669.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          157 c          125 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaac agtgtcgcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtatcctgg taccagcagc tccccggaac
      241 agctccccaa ctcctcatct attatgatga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aggtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agaggttaca tcttcggtga
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01005932             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:16768:12803
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005932
VERSION     KCWK01005932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:16768:12803"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..242
                     /note="immunoglobulin light chain variable region"
     V_region        13..242
     V_segment       13..207
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <170..>214
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71670.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       212..242
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        243..>280
                     /gene="IGLC"
BASE COUNT           59 a           88 c           69 g           64 t
ORIGIN      
        1 acatgggcat gctgtgtctt ggtaccaaca tcatccaggc aaagccccca aactcatgat
       61 ttatgaggtc aataaacggc ccgcaggggt ctctgatcgc ttctctggct ccaagtctgg
      121 caacacggcc tccctgacca tctctgggct ccagactgag gatgaggctg attattactg
      181 cagctcatat gcaggcagca acactttatt cttcggagga gggacccggc tgaccgtcct
      241 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005933             314 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:24598:13291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005933
VERSION     KCWK01005933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 314)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24598:13291"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..276
                     /note="immunoglobulin light chain variable region"
     V_region        6..276
     V_segment       6..236
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <204..>248
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71671.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       239..276
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        277..>314
                     /gene="IGLC"
BASE COUNT           68 a           97 c           79 g           70 t
ORIGIN      
        1 acatgggcat caatgttgct gcctaccaca tacattggta ccaacagaag ccagggagtc
       61 ctccccggta tcttctgaga tataaatcag actcagataa ggaccagggc tctggagtcc
      121 ccagccgctt ctctggatcc aaagatgcct cagcgaacac ggggcttttg cacatctctg
      181 ggctccagtc tgaggatgag gctgactact actgtgccat tgggcacagc agcggtgatt
      241 acatcttcgg tgctgggacc cgcctcaccg tcctaggtca gcccaaggct tcccccacgg
      301 tcactctgtt cccg
//
LOCUS       KCWK01005934             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:3250:9365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005934
VERSION     KCWK01005934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:3250:9365"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71672.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       410..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          153 c          130 g          113 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg gcagagggtc accatctcct
      181 gctctgggag cagctccaac atcggggcgg gtttttatgt ttcctggtac cagcagttcc
      241 caggaacagc ccccaaactc ctcatctttg aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggttcct cagcctccct gaccatcact ggactccaat
      361 ctgaggatga ggctgattat tattgttcat catgggaaag cagcctgaat tgggtattcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005935             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:12486:7716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005935
VERSION     KCWK01005935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12486:7716"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..254
                     /note="immunoglobulin light chain variable region"
     V_region        8..254
     V_segment       8..214
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71673.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       218..254
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           59 a           84 c           86 g           63 t
ORIGIN      
        1 acatggggga agtgaagttg tcaactggta ccaacagaag ccaccgcagg cccctgtggt
       61 ggtcatctat gctgattatg aacggccctc agggatccct gagcgattct ctggctccaa
      121 atcagggaac acggccaccc tgaccatcag cggagtcgcg gccggggatg aggctgacta
      181 ttactgtcag gtttgggaca tttatactga tcatccggtg ttgttcggag gagggacccg
      241 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005936             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18313:17319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005936
VERSION     KCWK01005936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18313:17319"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71674.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       412..446
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           90 a          153 c          127 g          114 t
ORIGIN      
        1 acatgggggt ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca cgatctcctg
      181 cagtgggagc aactccaaca ttggatatta ttatgtgcag tggtaccagc agcttccagg
      241 aacggccccc aaactcctca tctatgaaaa taataagcga ccctctgggg tttctgatcg
      301 attctctggc tcccagtctg gtacctcagc ctccctgacc atcactggac tccagtctga
      361 ggatgaggct gattattact gccactccta tgacagcagt ttgagtggtg tcttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01005937             299 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:13818:6451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005937
VERSION     KCWK01005937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 299)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13818:6451"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..261
                     /note="immunoglobulin light chain variable region"
     V_region        7..261
     V_segment       7..224
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <186..>233
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71675.1"
                     /translation="DYYCAVWDNSLTSPLF"
     J_segment       231..261
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        262..>299
                     /gene="IGLC"
BASE COUNT           62 a           95 c           72 g           70 t
ORIGIN      
        1 acatgggctc caacattgga aataattatg tatactggta ccagcacctc ccaggaacgg
       61 cccccaagct cctcatctat tatagttatc agcgaccctc aggggtccct gaccgattct
      121 ctggctctaa gtctggcacc tcagcctccc tggccatcac tggtctccga actgaggatg
      181 aggctgatta ttactgtgca gtatgggata acagcctgac cagtccgttg ttcggaggag
      241 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005938             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:10188:7122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005938
VERSION     KCWK01005938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10188:7122"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..391
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71676.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       392..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          152 c          117 g          104 t
ORIGIN      
        1 acatggggga cagaaggcag gactcaggac aatctccagc atggcctggt tccctctcgt
       61 cctcaccctc ctcactcact gtgcagggtc ctgggcccag tctgtgctga ctcagcctcc
      121 ctcagcgtct gaggccgcca ggaagagtgt caccatctcc tgttctggaa gcagctccaa
      181 catcggaagt aataatgtgt cctggtacca gcacctccca ggaacagctc ccaaactcct
      241 catctattat aatgatcaac gaggctcagg tgtctctgac cgattctctg gctccaagtc
      301 tggcacgtca gcttccctgg ccatcagtgg gctccagacc gaggatgagg ctgattatta
      361 ctgcgcagcg tgggatgata gcctgagcag ttacatcttc gctgctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005939             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:13552:5321
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005939
VERSION     KCWK01005939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13552:5321"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71677.1"
                     /translation="DYYCQSSHSRVNHPFF"
     J_segment       396..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT          104 a          137 c          123 g          100 t
ORIGIN      
        1 acatggggtg tggttctagg aggaagacct ctgggtgtct caccatgacc tggaccactg
       61 ttctgctccc ctttctcact ctctgcacag gctctgaggc ctcctatgag ctgacacagc
      121 caccctcagt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagaaacac
      181 tggcaaaaaa atatgctcag tggttccagc agaagccagg ccaggcccct gtgttggtga
      241 tatataaaga cagtgagagg ccctcaggga tccctgagcg attctctagc tccagttcag
      301 ggacaacagt taccttgacc atcagtgggg cccaggcaga agatgaggct gactattact
      361 gtcaatcatc gcacagcagg gttaatcatc cgtttttcgg aggagggacc cggctgaccg
      421 tcctaggaca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005940             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:18564:4438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005940
VERSION     KCWK01005940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18564:4438"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..400
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71678.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       409..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           92 a          154 c          123 g          108 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc ggacagaggg tcaccatctc ctgcattagc
      181 agcagctcca acatcggggc ggcttattat gtatcctggt accaacagtt accaggaaca
      241 gcccccaaac tcctcatctt tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggtcc ctcagcctcc ctgaccatca ctggactcca atctgaggat
      361 ggggctgatt attactgttt agcatgggat accagcctga attggatctt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005941             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:16699:9339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005941
VERSION     KCWK01005941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16699:9339"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71679.1"
                     /translation="DYYCQSVDSSAHHPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           99 a          139 c          121 g          106 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaccacagc tctgggtgtc tcaccatgac ctggaccact
       61 gttctgctcc cctttctcac tctctgcaca ggctctgagg cctcctatga ggtgacacag
      121 tcaccctcag tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagcaata
      181 ctggcaaata attatgctca gtggttccag cagaagccag accaggcccc tgtgttggtg
      241 atatataaag acactgagag gccctcaggg atccctgagc gattctctag ctccagttca
      301 gggacaacag ttaccttgac catcagtggg gcccaggcag aagatgaggc tgactattac
      361 tgtcaatcag ttgacagtag tgcccatcat ccgtttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005942             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:28320:12038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005942
VERSION     KCWK01005942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:28320:12038"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71680.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       400..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           90 a          154 c          124 g          106 t
ORIGIN      
        1 acatgggggg ggggtctcag gaggcggcac tctcgggaca tctccaccat ggcctgggat
       61 ctgctcctct tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagcctccct caatgtctgg gtctcctgga cagtcggtca ccatctccta cactggaacc
      181 agcagtgaca ttggtggtta taaccgtgtc tcctggtacc aacagcaccc aggcaaagac
      241 cccaaattca tgatttatga ggtcagtcaa cggccctcag gggtctctga tcgtatctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccagac tgaggatgag
      361 gctggttatt actgcagctc atttgcaggt accaacactg gcttaatcgg tggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01005943             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:13878:6084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005943
VERSION     KCWK01005943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13878:6084"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71681.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           87 a          159 c          123 g          112 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt agtaaaaaca tgtactggta ccagcagagg ccagggagcg ctcccaggtt
      241 attcctgtat tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caggtaacac agcgtttttg ctcatttctg gactccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtttgacagt agtgctgtgt tattcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01005944             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:26189:16137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005944
VERSION     KCWK01005944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:26189:16137"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..264
                     /note="immunoglobulin light chain variable region"
     V_region        9..264
     V_segment       9..227
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71682.1"
                     /translation="DYYCQVWGMTRDHPVF"
     J_segment       230..264
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>302
                     /gene="IGLC"
BASE COUNT           62 a           87 c           96 g           57 t
ORIGIN      
        1 acatgggggg gggagaccac attggaattg aggttgtgaa ctggtaccaa cagaagccac
       61 cgcaggcccc tgtggtggtc tatcctaata gcgaacggcc ctcagggatc cctgagcgat
      121 tctctggctc caaatcaggg aacacggcca ccctgaccat cagcggggtc gaggccgggg
      181 atgaggctga ctattactgt caggtgtggg gcatgactag ggatcatccg gtattcggcg
      241 gagggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      301 cg
//
LOCUS       KCWK01005945             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:19156:17728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005945
VERSION     KCWK01005945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19156:17728"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..401
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71683.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          155 c          122 g          109 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggtacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcagc ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct
      181 ggaagcagct ccaacatcgg aagtaataat gtgtcctggt accagcacct cccaggaaca
      241 gctcccaaac tcctcatcta ttataatgat caacgaggct caggtgtctc tgaccgattc
      301 tctggctcca agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat
      361 gaggctgatt attactgcgc agcgtgggat gatagcctga gtagttacat cttcgctgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005946             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:19408:7458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005946
VERSION     KCWK01005946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19408:7458"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..215
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71684.1"
                     /translation="EYYCCSYTTSSTYIF"
     J_segment       216..251
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           58 a           87 c           71 g           73 t
ORIGIN      
        1 acatgggggt aattctaact ctgtctcctg gtaccagaag cacccaggca aagcccccaa
       61 agtcatgatt tatggtgtca gtaatcgggc ctcaggggtc tctgatcgct tctctggctc
      121 caagtctggc aacgcggcct ccctgaccat ctctgggctc caggctgagg acgaggctga
      181 atattattgt tgttcatata caaccagtag tacttacatt ttcggtgctg ggacccggct
      241 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005947             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:17268:14049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005947
VERSION     KCWK01005947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17268:14049"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..423
                     /note="immunoglobulin light chain variable region"
     V_region        93..423
     V_segment       93..387
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71685.1"
                     /translation="DYYCAVWSSSAYIF"
     J_segment       388..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           82 a          150 c          114 g          115 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctgt cacagcctgt gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagtcagac tcacctgcat caatgttggt ggctactaca
      181 tattctggta ccagcagaag ccagggagtc ctccccggtt ccttctgaat tactactcag
      241 actcaaatca gggccagggc tctggagtcc ccagccgctt ctctggatcc aaagatgttt
      301 cagccaatgc agggctttta ctgatctctg ggctccagtc tgaggatgag gctgactatt
      361 actgtgccgt ttggtccagc agcgcttaca tcttcggtgg tgggactcgg ctcaccgtcc
      421 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01005948             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:17921:6766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005948
VERSION     KCWK01005948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17921:6766"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71686.1"
                     /translation="DYYCMIWHNNPYVLF"
     J_segment       404..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          154 c          115 g          114 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgcgcagt ggcatcagtg
      181 ttggtagtta caggatcttc tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gataaacacc agggatctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt atgatttggc acaacaatcc ttatgtgtta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005949             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:12804:17458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005949
VERSION     KCWK01005949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12804:17458"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71687.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          150 c          127 g          115 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcagt atttcttgca
      181 ctgggagcag ctccaacatt ggaggttatt atgtgcagtg gtaccagcag cttccaggaa
      241 cggcccccaa actcctcatc tatgaaaatg ataaacgacc ctcagggatt tctgatcgat
      301 tctctggctc ccagtctgat tcctcagcct ccctgaccat cactggactc cagtctgagg
      361 atgaggctga ttattactgc cagtcctatg acagcagctt gagtgttgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005950             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11007:12025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005950
VERSION     KCWK01005950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11007:12025"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71688.1"
                     /translation="DYYCSSYAGSNTFVLF"
     J_segment       404..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           86 a          160 c          128 g          104 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagccgcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggcggtt ataactatgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctgacgaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttcgtgttgt tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005951             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:10776:9765
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005951
VERSION     KCWK01005951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10776:9765"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71689.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       410..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          156 c          127 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accctctcct
      181 gcactgggag cagctccaac attggagatt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 acgatgaggc tgattattac tgtcagtcct atgatagcag cctgagtgtt gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01005952             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:10392:12874
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005952
VERSION     KCWK01005952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10392:12874"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71690.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           89 a          161 c          120 g          109 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcgtcaatg
      181 tgggttatta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacca gtcagactca aggaagcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc tgttactgat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccctatggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01005953             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:22281:14142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005953
VERSION     KCWK01005953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22281:14142"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71691.1"
                     /translation="DYYCQVCDMRSDQPLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          145 c          138 g           92 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggccc ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gagacaagat
      181 tggaagtgaa gttgtgaact ggtaccagca gaagccagcg cacgcccctg tgctggtcat
      241 ctatgctaat agcgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg ggtgaggctg actattactg
      361 tcaggtgtgt gacatgcgta gtgatcaacc gctattcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005954             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:17138:4743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005954
VERSION     KCWK01005954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17138:4743"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71692.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           88 a          143 c          127 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01005955             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:10105:17856
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005955
VERSION     KCWK01005955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10105:17856"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71693.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          147 c          130 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggtttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005956             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:12657:23504
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005956
VERSION     KCWK01005956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12657:23504"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71694.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          160 c          120 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatccacgag cctcaggtgt ctctgcccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcggcta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005957             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:11434:14919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005957
VERSION     KCWK01005957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:11434:14919"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..400
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71695.1"
                     /translation="DYHCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           96 a          161 c          114 g          105 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gtcagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgactacca cacacactgg taccaacaga agccagggag tcccccccgg tatcttctga
      241 aatacaaatc agacacagac cagggccagg ggtctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acaggtattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta tcactgtgcc attggtcaca gcagcggtcc atacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005958             299 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:4114:6705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005958
VERSION     KCWK01005958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 299)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:4114:6705"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..261
                     /note="immunoglobulin light chain variable region"
     V_region        6..261
     V_segment       6..225
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>233
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71696.1"
                     /translation="DYYCQVWDSSSKWVF"
     J_segment       226..261
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        262..>299
                     /gene="IGLC"
BASE COUNT           73 a           84 c           84 g           58 t
ORIGIN      
        1 acatgggcgg agacaacatt ggaattaaaa atgtccactg gtaccagcag aagccagcac
       61 aggcccctgt ggtagtcatc tatgctgata acaaacggcc ctcagggatc cctgagcgac
      121 tctctggctc caactcaggg aatattgcca ccctgaccat caacagggtc gaggccgggg
      181 atgaggcaga ctattactgt caggtgtggg acagtagtag taaatgggta ttcggcggag
      241 ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005959             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:9329:7736
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005959
VERSION     KCWK01005959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:9329:7736"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..380
                     /note="immunoglobulin light chain variable region"
     V_region        87..380
     V_segment       87..343
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>352
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71697.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       345..380
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        381..>418
                     /gene="IGLC"
BASE COUNT           80 a          124 c          128 g           86 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagt gtccccagga cagacggcca gggtcacctg
      121 tgggggagac aacatcggag gtgaagttgt gaattggtac cagcagaagc caccgcaggc
      181 ccctgtgttg gtcatctatg ctgatagcga gcggccctca gggatcccgg agcgattctc
      241 tggctccaaa tcagggaaca cggccaccct gaccatcagc ggggtcgagg ccggagatga
      301 ggctgactat tactgtcagg tgtgggacct taatagtcat catctgttat tcggaggagg
      361 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005960             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:21801:8585
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005960
VERSION     KCWK01005960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:21801:8585"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..434
                     /note="immunoglobulin light chain variable region"
     V_region        93..434
     V_segment       93..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71698.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       402..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>476
                     /gene="IGLC"
BASE COUNT           93 a          160 c          111 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttcttt
      241 actactactc agactcaagt aaccaccagg actctggagt ccccagccgc ttctctggat
      301 cgaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc acatggcaca gcagcgcttc ttacatcttc ggtgctggga
      421 cccggctcac cgtcttaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005961             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:23164:10317
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005961
VERSION     KCWK01005961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:23164:10317"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..380
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71699.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       392..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          147 c          132 g           98 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctccttt gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 acattggaat taaatttgtc cactggtacc agcagaagcc agcgcaggcc cctgtgaagg
      241 tcatctatgc tgatgacaaa cggccctcag ggatccctga gagattctct ggctccaatt
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 cctgtcaggt gtgggacagt gagactgatt attacatctt cggttctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01005962             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14386:20898
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005962
VERSION     KCWK01005962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14386:20898"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    77..398
                     /note="immunoglobulin light chain variable region"
     V_region        77..398
     V_segment       77..362
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <326..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71700.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       366..398
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>436
                     /gene="IGLC"
BASE COUNT           87 a          139 c          122 g           88 t
ORIGIN      
        1 acatgggggt gcctcagcca tggcctggac ccttctcctc ctcggcctcc tcgcttactg
       61 cacaggctct tcgacctcct atgaactgac tcagtcaccc tcagtgtcag cggcctcagg
      121 acagccggcc aggatcacct gtgggggaga caacattgga actaaaactg tgcactggta
      181 ccagcagaag ccaccgcagg gccctgtatt ggtcatcttt gctgacagta aacggccctc
      241 agggatccct gagcgattct ctggctccaa ctcagggaac accgccaccc tgaccatcag
      301 cggggtcgag gccggggatg aggctgacta ttactgtcag gtgtgggaca gtagtagtaa
      361 atggatattc ggcgggggga cccggctaac cgtcctaggt cagcccaagg ctgccccctc
      421 ggtcactctc ttcccg
//
LOCUS       KCWK01005963             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:4485:14969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005963
VERSION     KCWK01005963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:4485:14969"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..433
                     /note="immunoglobulin light chain variable region"
     V_region        86..433
     V_segment       86..393
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71701.1"
                     /translation="DYYCAIGHSSGNYIF"
     J_segment       400..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           90 a          156 c          114 g          111 t
ORIGIN      
        1 acatggggga aagaggctgt gtccaccatg gcctggactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctcccagcct atgctgactc agccggcctc cttctcagca
      121 tctcctggac cttcagccag tctcacatgc accttcagcg gtggcatcaa tgttgctggc
      181 taccacatac actggtacca gcagaagcca gggagtcctc cccggtttct tctgagatac
      241 aagtcagact cagataaggg ccagggctct ggagtcccca gccgcttctc tggatccaag
      301 gatgcttcag cgaacacagg aattttacgc atctctgggc tccagtctga ggatgaggct
      361 gactattact gtgccattgg gcacagcagc ggtaattata tcttcggtgc tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01005964             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:7364:16310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005964
VERSION     KCWK01005964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7364:16310"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71702.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          157 c          116 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cacgggtggc atcaatgttg
      181 ctgactacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 gatacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tggactccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gtagcggtga ttacatcttc gctggtggga
      421 cccggctcac cctcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005965             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:14847:5333
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005965
VERSION     KCWK01005965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14847:5333"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..389
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71703.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       391..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          150 c          121 g          107 t
ORIGIN      
        1 acatggggga caggaggcag cactcaggac agtctccagc atggcctggt ctcctctcct
       61 cctcaccctt ctcattcact gcacagggtc ctgggcccag tctgtgctga cgcagccgcc
      121 ctcagtgtct ggggcgcccg ggcagagggt caccctctcc tgcactggga gcagctccaa
      181 cattggagat tattatgtgc agtggtacca gcagcttcca ggaacggccc ccaaactcct
      241 catctatgaa aataataagc gaccctcagg ggtttctgat cgattctctg gctcccagtc
      301 tggtacctca gcctccctga ccatcactgg actccagtct gacgatgagg ctgattatta
      361 ctgtcagtcc tatgatagca gcctgagtgt tgtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005966             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:22064:4673
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005966
VERSION     KCWK01005966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22064:4673"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71704.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          153 c          116 g          102 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta ataatgtgtc ctggtaccag cacctcccag gaacagctcc caaactcctc
      241 atctactata atgatcaacg aggctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcgt gggatgatag actgagcagt tacatcttcg ctgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01005967             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:11648:3872
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005967
VERSION     KCWK01005967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11648:3872"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-63"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71705.1"
                     /translation="DYYCSAWDSSLTGGFF"
     J_segment       406..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          154 c          124 g          107 t
ORIGIN      
        1 acatgggggg cttcagctgt ggctagagaa gacaggactc aggacaatct ccagcatggc
       61 ctgcttccct ctcatcctca ccgtcctcac tcactgtgca ggatcctggg cccagtctgt
      121 gctgactcaa ccaccctcag cgtctggggc ccccgggcag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtaatta tgtatactgg taccagcagt tctcagggaa
      241 ggcccccaaa ctcctcatcc ataataataa tcagcgaccc tcaggggtcc ctgatcgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggacatc agtgggctcc agtccgagga
      361 tgaggctgat tattactgct cagcatggga tagcagtctg accggtggct ttttcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01005968             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:22178:10154
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005968
VERSION     KCWK01005968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22178:10154"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..393
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71706.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           89 a          153 c          122 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgtagct catatgcagg cagcaacagt ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005969             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:8988:6987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005969
VERSION     KCWK01005969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8988:6987"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71707.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       398..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          155 c          117 g          114 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaagct gccccgactc
      121 agcctccctc tgtgtccggg tctcctgggc agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtcttat aatgctgtgt cttggtacca acaacatcca ggcaaagccc
      241 cccaactcat aatttttgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatttctgg gctccaggct gaggatgagg
      361 ctgattatta ctgctgctca tatgtaggca gcaacactta catcttcgat gttgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01005970             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:14637:15577
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005970
VERSION     KCWK01005970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14637:15577"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71708.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          155 c          124 g          106 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag actccctcag cgtctgaggc cgccagaaag agtgtcacca tctcctgttc
      181 tggaagcagc tccaacatcg gaagaaatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agcgggctcc aggccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01005971             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:18869:9512
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005971
VERSION     KCWK01005971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18869:9512"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71709.1"
                     /translation="GYYCQVWDISSDHVLF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          140 c          138 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctttgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtgaa cttgtgaact ggtaccaaca gaggccaccg caggcccctg tgctggtcat
      241 ctatgctgat agcgaacggc cctcagggat ccctgaacga atctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg gctattactg
      361 tcaggtgtgg gacattagta gtgatcatgt gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005972             365 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:24863:14146
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005972
VERSION     KCWK01005972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 365)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 365)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24863:14146"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..327
                     /note="immunoglobulin light chain variable region"
     V_region        8..327
     V_segment       8..288
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <252..>299
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71710.1"
                     /translation="VYYCGAWDSSLSGYIF"
     J_segment       290..327
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        328..>365
                     /gene="IGLC"
BASE COUNT           73 a          115 c           97 g           80 t
ORIGIN      
        1 acatggggac gcagccgccc tcagtgtcta cggccccagg gcagaaggtc accatctcct
       61 gctctggaag tagctccaac atcgggagaa attctgtatc ctggtaccag caggtcccag
      121 gaacggcccc caaagtcctc atctatgaca ataataagcg cccctcgggg gtttctgacc
      181 gattctctgg ctccaagtct ggtacctcag cctccctggc catcactgga ctccaggctg
      241 gagatgaggc tgtttattac tgcggagcat gggatagcag tctgagtggt tacatcttcg
      301 gtgatgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt
      361 tcccg
//
LOCUS       KCWK01005973             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:8914:24793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005973
VERSION     KCWK01005973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8914:24793"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71711.1"
                     /translation="DYYCSSYAGSNALFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          155 c          120 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatgtt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgaaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag caacgcttta ttcttcggac gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005974             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:7969:5144
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005974
VERSION     KCWK01005974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7969:5144"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..409
                     /note="immunoglobulin light chain variable region"
     V_region        79..409
     V_segment       79..374
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71712.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       379..409
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           86 a          147 c          109 g          105 t
ORIGIN      
        1 acatgggagg acttctccac catggtctgg gctctgctcc tcctcaccct cctcactcag
       61 ggcacaggat cctgggctca ggctgccccg actcagactc cctctgtgtc cgggtctcct
      121 ggacagtcgg tcaccatctc ctgcactgga accagcagtg atattgggta ttatcatgct
      181 gtgtcttggt accaacatca tccaggcaaa gcccccaaac tcatgattta tgaggtcaat
      241 aaacggcccg caggggtctc tgatcgcttc tctggctcca agtctggcaa cacggcctcc
      301 ctgaccatct ctgggctcca gactgaggat gaggctgatt attactgcag ctcatatgca
      361 ggcagcaaca ctttattctt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005975             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:14582:5731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005975
VERSION     KCWK01005975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:14582:5731"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71713.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          148 c          130 g           95 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttcc
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg ttctggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga atctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtc ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005976             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:9718:20657
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005976
VERSION     KCWK01005976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9718:20657"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..444
                     /note="immunoglobulin light chain variable region"
     V_region        100..444
     V_segment       100..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71714.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          159 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccta gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacga tagtgctgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01005977             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:24159:3441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005977
VERSION     KCWK01005977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24159:3441"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..393
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71715.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          159 c          120 g          103 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 ctcactctcc tccttcactg cacagggtct ctctcccagc ctgtgttgac tcagtcgccc
      121 tctgtctctg cctccctggg agcctcggtc aaactcacct gcactctgaa cagtgggcac
      181 agcagctaca ccatcgcatg gcatcagcat cagcaaggga aggccccccg gtacttgatg
      241 tggcttaaaa gtgatggcag ccatagccag ggggacggga tccctgatcg cttttcaggc
      301 tccagctccg gggctgagcg ctacctcacc atctccaacc tccagtctga ggatgaggct
      361 gattattact gtcagacctg ggatactgac attgtgttgt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01005978             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:14429:11237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005978
VERSION     KCWK01005978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14429:11237"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..434
                     /note="immunoglobulin light chain variable region"
     V_region        86..434
     V_segment       86..395
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71716.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       397..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           94 a          153 c          109 g          116 t
ORIGIN      
        1 acatgggggg aaagaggctg tgtccaccat ggcctggact cctctcctcc tcctgctcct
       61 ctctcactgc acaggttccc tctcgcagcc tgtgctgact cagccaacct ccctctcagc
      121 ttctcctgga gcatcagcca gactcacctg caccttgaac agtggcatca gtgttgctaa
      181 ttacaggata ttctggtacc accagaagcc agggagtcct ccccggtatc ttctgaacta
      241 ccacacagac tcagatattc accagggctc tggagtcccc agccgcttct ctggatccaa
      301 agatgcttcg gccaatgcag ggattttact catctctgga ctccagtctg aggatgaggc
      361 tgactattac tgtatgattt ggcacaacaa tgcttattgg gttttcggcg gagggacccg
      421 gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01005979             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:18353:13773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005979
VERSION     KCWK01005979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18353:13773"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71717.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           89 a          154 c          120 g          110 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gcaacacttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005980             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:28765:11341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005980
VERSION     KCWK01005980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:28765:11341"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71718.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          147 c          128 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtacact ggtaccagca caagtcaccg caggcccctg ttctgctcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttgttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005981             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:20117:5302
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005981
VERSION     KCWK01005981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20117:5302"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..455
                     /note="immunoglobulin light chain variable region"
     V_region        110..455
     V_segment       110..418
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71719.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       419..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           91 a          166 c          125 g          111 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      181 gagcagtgac ctcagtgttg gtagtaaaaa catgtactgg taccagcaga ggccagggag
      241 cgctcccagg ttattcctgt attactactc cgactcagac aagcagctgg gacctggggt
      301 ccccaatcga gtctctggct ccaaggagac ctcaggtaac acagcgtttt tgctcatctc
      361 tggactccag cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctgt
      421 gttattcgga ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCWK01005982             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:14115:12946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005982
VERSION     KCWK01005982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:14115:12946"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..249
                     /note="immunoglobulin light chain variable region"
     V_region        6..249
     V_segment       6..211
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <174..>221
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71720.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       217..249
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        250..>287
                     /gene="IGLC"
BASE COUNT           57 a           84 c           91 g           55 t
ORIGIN      
        1 atgggggaag tgaagttgtg aactggtacc agcagaagcc agcgcaggcc cctgtgctgg
       61 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaaat
      121 cagggaacac ggccaccctg accatcagcg gggtcgaggc cgggggtgag gctgactatt
      181 actgtcaggt gtgggacatg cgtagtgatc aaccgctatt cggcggaggg acccggctaa
      241 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01005983             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:4772:12685
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005983
VERSION     KCWK01005983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:4772:12685"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..256
                     /note="immunoglobulin light chain variable region"
     V_region        7..256
     V_segment       7..222
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <186..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71721.1"
                     /translation="DYYCCSHSTSSTYVF"
     J_segment       223..256
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        257..>296
                     /gene="IGLC"
BASE COUNT           54 a           97 c           69 g           76 t
ORIGIN      
        1 acatgggtga cgttggtggt tctaactctg tctcctggta ccaacaacac ccaggcaaag
       61 cccccaaact catgattttt ggtgtcaata atcggccctc tggggtctct gaccgcttct
      121 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag tctgaggacg
      181 aggctgatta ttactgttgt tcacattcaa ccagtagcac ttacgtcttc ggtcctggga
      241 cccggctcac cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01005984             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:15719:11554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005984
VERSION     KCWK01005984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15719:11554"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..434
                     /note="immunoglobulin light chain variable region"
     V_region        86..434
     V_segment       86..397
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71722.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       398..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           96 a          160 c          108 g          108 t
ORIGIN      
        1 acatgggggg aaagaggctg tgtccaccat ggcctggact cctctcctcc tcctgctcct
       61 ctctcactgc acaggttccc tctccaagcc tatgctgact cagccggcct ccctctcagc
      121 aactcctgga gcatcagcca gtctcacatg caccttcagc ggtggcatca atgttgttgc
      181 ctaccacata cactggtacc agcagaagcc agggagtccc ccccggtatc ttctgagtta
      241 caaatcagac tcagataagg gccagggctc tggagtcccc agccgcttct ctggatccaa
      301 aaatgcttca acaaacacag gcattttaca catctctggg ctccagtctg aggatgaggc
      361 tgactatttc tgtgccattg gacacagcag cggtccttac atcttcggtg ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01005985             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:21302:14586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005985
VERSION     KCWK01005985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21302:14586"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71723.1"
                     /translation="DYYCQSVDSSGNHPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          132 c          124 g          104 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctcttcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc agtggttcca gcagaagcca ggccaggccc ctgtgttggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgaa cgattctcta gttccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggta gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggtaatca tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005986             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:13829:15645
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005986
VERSION     KCWK01005986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:13829:15645"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..278
                     /note="immunoglobulin light chain variable region"
     V_region        5..278
     V_segment       5..241
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <206..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71724.1"
                     /translation="DYSCAIGHSSGPYIF"
     J_segment       242..278
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>316
                     /gene="IGLC"
BASE COUNT           71 a           99 c           76 g           70 t
ORIGIN      
        1 acatgggggc atcaatgttg ctgactacca catacactgg taccagcaga agccagggag
       61 tcccccccgg tatcttctga gttacaaatc agactcagat aagggccagg gctctggagt
      121 ccccagccgc ttctctggat ccaaaaatac ttcaacgaac acaggcattt tacacatctc
      181 tgggctccag tctgaggatg aggctgacta ttcctgtgcc attggacaca gcagcggtcc
      241 ttacatcttc ggtgctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac
      301 ggtcactctg ttcccg
//
LOCUS       KCWK01005987             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:22135:15338
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005987
VERSION     KCWK01005987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22135:15338"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71725.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          161 c          113 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac ccagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005988             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:21184:9839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005988
VERSION     KCWK01005988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21184:9839"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71726.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          156 c          127 g          112 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agtctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagtc tgagcggtta catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005989             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:15153:9459
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005989
VERSION     KCWK01005989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15153:9459"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..442
                     /note="immunoglobulin light chain variable region"
     V_region        114..442
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71727.1"
                     /translation="DYYCAAWDDSLTGYIF"
     J_segment       408..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>482
                     /gene="IGLC"
BASE COUNT           93 a          160 c          120 g          109 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcctcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ttccaacatc ggaagtaata gtgtatcctg gtaccaacaa ctccccgaaa
      241 cggctcccaa actcctcatc tattataatc atcggcgggc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtccggc acttcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gaccggttac atcttcggta
      421 ctgggacccg gctcaccgtc ctgggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01005990             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:7091:3580
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005990
VERSION     KCWK01005990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7091:3580"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71728.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       215..251
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           59 a           89 c           75 g           66 t
ORIGIN      
        1 acatgggggt ggttataacc gtgtctcctg gtaccaacag cacccaggca aagaccccaa
       61 attcatgatt tatgaggtca gtcaacggcc ctcaggggtc tctgatcgta tctctggctc
      121 caagtctggc aacacggcct ccctgaccat ctctgggctc cagactgagg atgaggctgg
      181 ttattactgc agctcatttg caggtaccaa cactggctta atcggtggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01005991             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:16703:10066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005991
VERSION     KCWK01005991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16703:10066"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..435
                     /note="immunoglobulin light chain variable region"
     V_region        87..435
     V_segment       87..396
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71729.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       398..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           95 a          153 c          109 g          116 t
ORIGIN      
        1 acatgggagg gaaagaggct gtgtccacca tggcctggac tcctctcctc ctcctgctcc
       61 tctctcactg cacaggttcc ctctcgcagc ctgtgctgac tcagccaacc tccctctcag
      121 cttctcctgg agcatcagcc agactcacct gcaccttgaa cagtggcatc agtgttgcta
      181 attacaggat attctggtac caccagaagc cagggagtcc tccccggtat cttctgaact
      241 accacacaga ctcagatatt caccagggct ctggagtccc cagccgcttc tctggatcca
      301 aagatgcttc ggccaatgca gggattttac tcatctctgg actccagtct gaggatgagg
      361 ctgactatta ctgtatgatt tggcacaaca atgcttattg ggttttcggc ggagggaccc
      421 ggctaaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005992             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:21495:8685
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005992
VERSION     KCWK01005992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21495:8685"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..260
                     /note="immunoglobulin light chain variable region"
     V_region        8..260
     V_segment       8..225
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>234
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71730.1"
                     /translation="DYYCAIWHSSASCIF"
     J_segment       228..260
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>300
                     /gene="IGLC"
BASE COUNT           57 a           96 c           73 g           74 t
ORIGIN      
        1 acatggggtt acagcatttt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
       61 ctctactact actcagactc aactaagcac cagggctctg gagtccccag ccgcttctct
      121 ggatccaaag atgattcagc caatgcaggg cttttactga tctctgggct ccagtctgag
      181 gatgaggctg actattactg tgccatttgg cacagcagcg cttcttgcat cttcggtcct
      241 gggacccggc tcaccgtcct gggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01005993             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:7925:13350
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005993
VERSION     KCWK01005993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:7925:13350"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..387
                     /note="immunoglobulin light chain variable region"
     V_region        63..387
     V_segment       63..349
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <312..>359
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71731.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       351..387
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        388..>425
                     /gene="IGLC"
BASE COUNT           83 a          136 c          115 g           91 t
ORIGIN      
        1 acatgggggc ctggactttt ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg
       61 cctcctatga tctgactcag ccaccctcgg tgtcagtgtc cccaggacag acggccagga
      121 tcacctgtgg gggagacaac attggaagtc aaagtgtaca ctggtaccag cacaagccac
      181 cgcaggcccc tgttctggtc atcttttatt ataccgaacg gccctcagga atccctgagc
      241 gattctctgg ctccaaatca gggaacaccg ccaccctgac catcagcggg gtcgaggccg
      301 gggatgaggc tgactattac tgtcaggtgt gggacacaac tattgatcac ggcttgttcg
      361 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      421 tcccg
//
LOCUS       KCWK01005994             515 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:17693:12698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005994
VERSION     KCWK01005994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 515)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 515)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..515
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17693:12698"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    144..475
                     /note="immunoglobulin light chain variable region"
     V_region        144..475
     V_segment       144..440
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <405..>449
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71732.1"
                     /translation="DYYCQSSDGNYNRLF"
     J_segment       443..475
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        476..>515
                     /gene="IGLC"
BASE COUNT           96 a          162 c          143 g          114 t
ORIGIN      
        1 acatggggat tacagtgaaa gataagaagg gctggtggct cattcctggc tgtggctcag
       61 gaagcagagc ctggagcgtc tccaccatgg cctgggctcc actcctcctc accctcctcg
      121 ctcactgcac agggtcttgg gctgaggttc tgttcacgca gtcccattct gtgtcggggt
      181 ctccggggca gacggtcacc atctcctgta cccgcagcag aggcagcatt gacagtagtt
      241 atgtgcagtg gtaccagcag cgcccgggca gtgccccgac cacagtgatt tacagagata
      301 accaaagagc ctctggggtc cctgatcggt tctctggctc catcgacagc tcctccaact
      361 ctgcctccct caccatctct gggctgaagt ctgaggacga ggctgactac tactgtcagt
      421 cttctgatgg caactacaat cggttattcg gaggagggac ccggctgacc gtcctgggtc
      481 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01005995             326 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:16958:17883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005995
VERSION     KCWK01005995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 326)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16958:17883"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..288
                     /note="immunoglobulin light chain variable region"
     V_region        8..288
     V_segment       8..232
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <210..>260
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71733.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       252..288
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        289..>326
                     /gene="IGLC"
BASE COUNT           70 a           90 c           97 g           69 t
ORIGIN      
        1 acatggggac ggccaggatc acctgtggag gagacaacat tggaagtgaa gttgtcaatt
       61 ggtaccagca gaagccaccg caggcccctg tgctggtcat ctatgctgat tatgaacggc
      121 cctcagggat ccctgagcga ttctctggct ccaaatcagg gaacacggcc accctgacca
      181 tcagcggagt cgaggccggg gatgaggctg actattattg tcaggtgtgg gacatttata
      241 ttgaccatcc ggtgttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      301 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005996             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:19212:9882
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005996
VERSION     KCWK01005996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19212:9882"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71734.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          107 a          138 c          121 g          100 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggctgac ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg acctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagaagcca ggccagggcc ctagactggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagcgg ggcccagaca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagaa gtcctaatca tgtgtttttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01005997             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:8477:4914
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005997
VERSION     KCWK01005997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8477:4914"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..398
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71735.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       399..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           90 a          154 c          122 g          107 t
ORIGIN      
        1 acatggggtg gggtctcagg aggcggcact ctcgggacat ctccaccatg gcctgggatc
       61 tgctcctctt caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctccctc aatgtctggg tctcctggac agtcggtcac catctcctac actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagacc
      241 ccaaattcat gatttatgag gtcagtcaac ggccctcagg ggtctctgat cgtatctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctggttatta ctgcagctca tttgcaggta ccaacactgg cttaatcggt ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01005998             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:12404:5734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005998
VERSION     KCWK01005998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12404:5734"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71736.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          156 c          127 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga acagtgtcgc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatgat gatcaacgag cctcgggtgt ctctgaccga
      301 ttctctggct ccaggtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagaggtta catcttcggt
      421 gatgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01005999             498 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:26772:15632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01005999
VERSION     KCWK01005999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 498)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:26772:15632"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..458
                     /note="immunoglobulin light chain variable region"
     V_region        130..458
     V_segment       130..423
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>432
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71737.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       424..458
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        459..>498
                     /gene="IGLC"
BASE COUNT           90 a          159 c          134 g          115 t
ORIGIN      
        1 acatggggag atttgggtga agcgcagctt cagctgtggg tccagaaggc aggactcagg
       61 acaatctcca gcatggcctg gttccctctc gtcctcaccc tcctcactca ctgtgcaggg
      121 tcctgggccc agtctgtgct gactcagcct ccctcagcgt ctgaggccgc caggaagagt
      181 gtctccatct cctgttctgg aagcagctcc aacatcggaa gtcatagtgt ctcctggtac
      241 cagcagctcc caggaacagc tcccaaactc ctcatctatt atagtgatca acgagcctca
      301 ggtgtctctg accgattctc tggctctcag tctggcacgt cagcctccct ggccatcagt
      361 gggctccagg ccgaggatga ggctgattat tactgcgcag catgggatga tagtctgagc
      421 ggttacatct tcggtgctgg gacccggctc gccgtcctgg gtcagcccaa ggcttccccc
      481 acggtcactc tgttcccg
//
LOCUS       KCWK01006000             287 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:20783:19978
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006000
VERSION     KCWK01006000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 287)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20783:19978"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..249
                     /note="immunoglobulin light chain variable region"
     V_region        1..249
     V_segment       1..212
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <174..>221
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71738.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       213..249
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        250..>287
                     /gene="IGLC"
BASE COUNT           61 a           86 c           68 g           72 t
ORIGIN      
        1 acatgggaga ttattttgtg cagtggtacc agcaccttcc aggaacggcc cccaaactcc
       61 tcatctatga aaataataag cgaccctcag ggatttctga tcgattctct ggctcccagt
      121 ctggaacctc agcctccctg accatcactg gactccagtc tgaggatgag gctgattatt
      181 actgccagtc ctatgacagc agtttgattg ctgtgttatt cggaggaggg acccggctga
      241 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01006001             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:14730:7543
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006001
VERSION     KCWK01006001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14730:7543"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..400
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71739.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           95 a          154 c          111 g          117 t
ORIGIN      
        1 atggggactg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcg cagcctgtgc tgactcagcc aacctccctc
      121 tcagcttctc ctggagcatc agccagactc acctgcacct tgaacagtgg catcagtgtt
      181 gctaattaca ggatattctg gtaccaccag aagccaggga gtcctccccg gtatcttctg
      241 aactaccaca cagactcaga tattcaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcggccaa tgcagggatt ttactcatct ctggactcca gtctgaggat
      361 gaggctgact attactgtat gatttggcac aacaatgctt attgggtttt cggcggaggg
      421 acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01006002             383 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:6828:11396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006002
VERSION     KCWK01006002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 383)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 383)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6828:11396"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    15..345
                     /note="immunoglobulin light chain variable region"
     V_region        15..345
     V_segment       15..308
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <273..>317
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71740.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       310..345
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        346..>383
                     /gene="IGLC"
BASE COUNT           82 a          115 c           97 g           89 t
ORIGIN      
        1 acatgggaaa ttctcaggct gtagtgactc aggagccctc aatgactgtg tccccaggag
       61 ggacagtcac tctcacctgt gcttccagca ctggagcagt caccagtggt cactctccac
      121 actggttcca gcagaaacct ggacaagccc ccaagacact gatttataat acaaactaca
      181 gacactcctg gactcctgcc cggttctcag gctccctcct tgggggtaaa gctgccctga
      241 cactgtcagg tgcgcagcct gaggatgagg ctgagtatta ttgtttactg tactatagtg
      301 gtgctcagct gttattcgga ggagggacct ggctgaccgt cctaggtcag cccaaggctg
      361 ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006003             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:22636:5317
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006003
VERSION     KCWK01006003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22636:5317"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71741.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           93 a          161 c          108 g          111 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgttct gacccagcca acctccctct
      121 cagcatctcc gggaacatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt cctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01006004             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:13855:16183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006004
VERSION     KCWK01006004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13855:16183"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..395
                     /note="immunoglobulin light chain variable region"
     V_region        99..395
     V_segment       99..357
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <323..>367
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71742.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       362..395
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        396..>433
                     /gene="IGLC"
BASE COUNT           84 a          141 c          110 g           98 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agactcccct gcaccctgag
      121 cactgacctc agtgttggtg gtaaaaacat gtactggtac cagcagaagc caggaagcgc
      181 tcccaggtta ttgctgtatt accactccga ctcagacaag cagctgggac ctggggtccc
      241 caatcgagtc tctggctcca aggagacctc aagtaacaca gcgtttttgc tcatctctgg
      301 gctccagcct gaggacgagg ccgattatta ctgtcaggtg tatgacagta gtgccaacac
      361 tttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      421 cactctcttc ccg
//
LOCUS       KCWK01006005             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:20259:11754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006005
VERSION     KCWK01006005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20259:11754"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71743.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          158 c          127 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tcgggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca actcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct cccagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcggcatgg gatgatagcc tgagcggtta catcttcggt
      421 ggtgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01006006             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10338:14349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006006
VERSION     KCWK01006006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10338:14349"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71744.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          157 c          119 g          109 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcacc tccaacatcg gaagcaataa tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctctttt attataatga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctcttgctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgataacctg agcggctaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01006007             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:23403:16456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006007
VERSION     KCWK01006007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23403:16456"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71745.1"
                     /translation="DYYCHVYDSSINVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          162 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtattaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01006008             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:4123:14396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006008
VERSION     KCWK01006008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4123:14396"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..455
                     /note="immunoglobulin light chain variable region"
     V_region        125..455
     V_segment       125..418
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71746.1"
                     /translation="DYYCAAWDDRLTGYVF"
     J_segment       425..455
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           94 a          159 c          130 g          110 t
ORIGIN      
        1 acatgggggg ggtgaagcgc agcttcagct gtgggtacag aaggcaggac tcaggacaat
       61 ctccagcatg gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg
      121 ggcccagtct gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac
      181 catctcctgt tctggaagca gctccaacat cgggagcaat agtgtatcct ggtaccagct
      241 actcccagaa acggctccca aactcctcat ctattataat aatcggcgag cctcaggtgt
      301 ctctgaccga ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct
      361 ccagaccgag gatgaggctg attattactg cgcagcatgg gatgatcgcc tgaccggtta
      421 cgtattcggt gttgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt
      481 cactctgttc ccg
//
LOCUS       KCWK01006009             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:21885:18377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006009
VERSION     KCWK01006009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21885:18377"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..451
                     /note="immunoglobulin light chain variable region"
     V_region        130..451
     V_segment       130..415
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71747.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       416..451
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT          105 a          150 c          132 g          102 t
ORIGIN      
        1 acatggggga gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactcccca tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agaagaattg ccaaaaaaat atgcttattg gttccagcag
      241 aagccaggcc agtcccctgt ccagatcatc tatgaggaca gtaaacggcc ctctgggatc
      301 cctgagagaa tctctggctc cagctcaggg acagtggcca ccttgactat cactggggcc
      361 caggtggagg atgaagctga ctactactgt ttctcaacag acaccagtgg taatcgggta
      421 ttcggcggag ggacccgtct aaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCWK01006010             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:5054:17760
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006010
VERSION     KCWK01006010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:5054:17760"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71748.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          165 c          122 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcgtccccg ggagcatcgg ccagactccc ctgcaccctg accagtgacc
      181 tcagcgttgg tagtaaaaac atgtattggt accagcagaa gccagggagc actcccaggt
      241 cattcctcta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgactat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01006011             453 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:14900:20986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006011
VERSION     KCWK01006011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 453)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14900:20986"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..415
                     /note="immunoglobulin light chain variable region"
     V_region        94..415
     V_segment       94..379
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <343..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71749.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       383..415
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>453
                     /gene="IGLC"
BASE COUNT           93 a          140 c          129 g           91 t
ORIGIN      
        1 acatggggag gaggcagcat tgacggtgcc tcagccatgg cctggaccct tctcctcctc
       61 ggcctcctcg cttactgcac aggctctgcg acctcctatg aattgactca gtcaccctca
      121 gtgtcagcgg cctcaggaca gccggccagg atcacctgtg ggggagacaa cattggaact
      181 aaaactgtgc actggtacca acagaagcca ccgcagggcc ctgtattggt catctttgct
      241 gatagtagac ggccctcagg gatccctgag cgattctctg gctccaactc agggaacacc
      301 gccaccctga ccatcagcag ggtcgaggcc ggggatgagg ctgactatta ctgtcaggtg
      361 tgggacagta gtagtaaatg gatattcggc ggggggaccc ggctaaccgt cctaggtcag
      421 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006012             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:7714:18033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006012
VERSION     KCWK01006012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:7714:18033"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71750.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       414..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           90 a          159 c          129 g          110 t
ORIGIN      
        1 acatggggga agcgcagctt cagctgtggg tacagaaggc aggactcagg acaatctcca
       61 gcatggcctg gttccctctc gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc
      121 agtctgtgct gactcagcct ccctcagcgt ctgaggccgc cgggaagagt gtctccatct
      181 cctgttctgg aagcagctcc aacatcggaa gtcatagtgt ctcctggtac cagcagctcc
      241 caggaacagc tcccaaactc ctcatctatt atagtgatca acgagcctca ggtgtctctg
      301 accgattctc tggctctcag tctggcacgt cagcctccct ggccatcagt gggctccaga
      361 ccgaggatga ggctgattat tactgcgcag catgggatga tagcctgagc ggttacatct
      421 tcggtgctgg gacccggctc gccgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCWK01006013             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:17536:2903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006013
VERSION     KCWK01006013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17536:2903"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71751.1"
                     /translation="DYYCAAWDDRLTGYVF"
     J_segment       401..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           89 a          154 c          121 g          105 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cctcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtcaccatc tcctgttctg gaagcagctc
      181 caacatcggg agcaatagtg tatcctggta ccagctgctc ccagaaacgg ctcccaaact
      241 cctcatctat tataataatc ggcgagcctc aggtgtctct gaccgattct ctggctccaa
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcatgggatg atcgcctgac cggttacgta ttcggtgttg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01006014             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:19777:10384
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006014
VERSION     KCWK01006014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19777:10384"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71752.1"
                     /translation="EYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           86 a          160 c          120 g          105 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggg
      181 cactatagtt ataccatcgc atggcatcaa caatatcaag ggaaggcccc tcggttcttg
      241 atgtggctta aaagtgatgg cagccacacc aagggggacg ggatccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc tccatctcca acctccagtc tgaggatgag
      361 gctgagtatt actgtcagac ctgggacatt ggcatttggg tattcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01006015             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:8557:16903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006015
VERSION     KCWK01006015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8557:16903"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..440
                     /note="immunoglobulin light chain variable region"
     V_region        89..440
     V_segment       89..403
                     /gene="IGLV5-107"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71753.1"
                     /translation="DYYCCTWHGSSKTQIF"
     J_segment       408..440
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           88 a          159 c          117 g          114 t
ORIGIN      
        1 acatggggag ggctcagggg ctctgtccac catggcctgg actcttctcc ttctcatgct
       61 cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccat cttcccattc
      121 cgcatctcct ggagcgccag ccagactcac ctgcacgctg agcagtggct tcagtgttgg
      181 tgacttctgg atacggtggt accaacaaaa gccagggagc cctccccggt atctcctgta
      241 ctaccactca gactcagata accaccgagg ctctggagtt cccagccgct tctctggatc
      301 caatgatgca tcagccaatg cagggattct ctttatctct gggctccagc ctgaggatga
      361 ggctgactat tactgttgta catggcatgg cagctctaag actcagatat tcggcggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01006016             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:5196:7361
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006016
VERSION     KCWK01006016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5196:7361"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..266
                     /note="immunoglobulin light chain variable region"
     V_region        8..266
     V_segment       8..229
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71754.1"
                     /translation="DYYCSSYAGSDTFVLF"
     J_segment       230..266
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           61 a           97 c           77 g           69 t
ORIGIN      
        1 acatgggagc agtgacatcg gtggttataa ctatgtctcc tggtaccaac aacatccagg
       61 cacagccccc aaactcgtga tttatgaggt caatcagcgg ccctcagggg tctctgatcg
      121 cttctctggc tccaagtctg acaacacggc ctccctgacc atctctggcc tccagcctga
      181 ggacgaggct gattattact gcagctcgta tgcaggcagc gacactttcg tgttattcgg
      241 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      301 cccg
//
LOCUS       KCWK01006017             353 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:17469:14264
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006017
VERSION     KCWK01006017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 353)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17469:14264"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..315
                     /note="immunoglobulin light chain variable region"
     V_region        9..315
     V_segment       9..279
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>287
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71755.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       283..315
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        316..>353
                     /gene="IGLC"
BASE COUNT           77 a          104 c          105 g           67 t
ORIGIN      
        1 acatggggca gtcaccctca gtgtcagcgg cctcaggaca gccggccagg atcacctgtg
       61 ggggagacaa cattggaact aaaactgtgc actggtacca acagaagcca ccgcagggcc
      121 ctgtattggt catctttgct gatagtagac ggccctcagg gatccctgag cgattctctg
      181 gctccaactc agggaacacc gccaccctga ccatcagcag ggtcgaggcc ggggatgagg
      241 ctgactatta ctgtcaggtg tgggacagta gtagtaaatg gatattcggc ggggggaccc
      301 ggctaaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006018             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:11333:8265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006018
VERSION     KCWK01006018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11333:8265"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71756.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          162 c          124 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtggcc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006019             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:14012:19813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006019
VERSION     KCWK01006019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14012:19813"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..262
                     /note="immunoglobulin light chain variable region"
     V_region        1..262
     V_segment       1..226
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>234
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71757.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       230..262
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        263..>300
                     /gene="IGLC"
BASE COUNT           67 a           85 c           89 g           59 t
ORIGIN      
        1 acatgggggg gagacaacat tggaactaaa actgtgcact ggtaccaaca gaagccaccg
       61 cagggccctg tattggtcat ctttgctgat agtagacggc cctcagggat ccctgagcga
      121 ttctctggct ccaactcagg gaacaccgcc accctgacca tcagcagggt cgaggccggg
      181 gatgaggctg actattactg tcaggtgtgg gacagtagta gtaaatggat attcggcggg
      241 gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01006020             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:19189:19111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006020
VERSION     KCWK01006020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19189:19111"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71758.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           93 a          163 c          109 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccaaac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaagga tgcttcggcc aatgcaggcc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01006021             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:15049:19731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006021
VERSION     KCWK01006021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15049:19731"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71759.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          161 c          122 g          111 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gattcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtaataaaaa catgtactgg taccaacaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaactaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtttgaca gtagtgctgt gttgttcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01006022             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:25021:20257
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006022
VERSION     KCWK01006022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:25021:20257"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71760.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       413..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           87 a          154 c          136 g          111 t
ORIGIN      
        1 acatgggggg ggaagctctg cttcagctgt gggcacagga ggcagcactc aggacagtct
       61 ccagcatggc ctggtctctc cttctcactc tgctggttca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagcat ctggggcccc cgggcagagg gttaccatct
      181 cctgcactgg gagcagctcc aacatcgggg cgggttttta tgtgtcctgg taccagcagt
      241 tccctgggac agcccccaaa ctcctcatct ttgaaaataa taagcgaccc tcaggggttt
      301 ctgaccgatt ctctggctcc aagtctggtt cctcagcctc cctgaccatc actggactcc
      361 agtctgagga tgaggctgat tattactgct catcatggga aagcagcctg aattgggtat
      421 tcggcggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01006023             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:18626:14094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006023
VERSION     KCWK01006023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18626:14094"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71761.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           93 a          159 c          111 g          110 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 caacatctcc gggagcatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt ggtgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01006024             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:7161:11908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006024
VERSION     KCWK01006024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:7161:11908"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..391
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71762.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       393..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          150 c          121 g          108 t
ORIGIN      
        1 acatggggga cacaggaggc agcactcagg acagtctcca gcatggcctg gtctcctctc
       61 ctcctcaccc ttctcattca ctgcacaggg tcctgggccc agtctgtgct gacgcagccg
      121 ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct cctgcactgg gagcagctcc
      181 aacattggag gttattatgt gcagtggtac cagcagcttc caggaacggc ccccaaactc
      241 ctcatctatg aaaatgataa acgaccctca ggggtttctg atcgattctc tggctcccag
      301 tctgattcct cagcctccct gaccatcact ggactccagt ctgaggatga ggctgattat
      361 tactgccagt cctatgacag cagcttgagt gttgtgttat tcggaggagg tacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01006025             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:28159:17138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006025
VERSION     KCWK01006025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:28159:17138"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71763.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          158 c          123 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctccggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01006026             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:13682:6310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006026
VERSION     KCWK01006026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13682:6310"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71764.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          156 c          126 g          114 t
ORIGIN      
        1 acatggggct gcttcaccgg tgttgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc tccatctcct
      181 gcactgggag cagctccaac attggagatt tttatgtgca gtggtaccag caccttccag
      241 gaacggcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggaacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag tttgattgct gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01006027             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:16042:12832
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006027
VERSION     KCWK01006027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16042:12832"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71765.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       216..251
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           59 a           91 c           73 g           66 t
ORIGIN      
        1 acatggggga ggttattata tatcctggta ccagcagctc ccaggaacgg cccccaaact
       61 cctcgtctat gacaataata agcgaccctc aggggtttct gaccgattct ctggctccaa
      121 gtctggttcc tcagccaccc tgaccatcac tgggctccag actgaggatg aggctgatta
      181 ttactgccag tcctatgaca gcagtctgag tgctcgggta ttcggcggag ggacccggct
      241 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006028             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:15514:2511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006028
VERSION     KCWK01006028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15514:2511"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71766.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           91 a          153 c          121 g          108 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac agtcggtcac catctactgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca acatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgactatta ctgcagctca tatgcaggca gcaacagttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006029             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:21783:18567
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006029
VERSION     KCWK01006029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:21783:18567"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..390
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71767.1"
                     /translation="DYFCCSHAGSDFFVLF"
     J_segment       403..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           84 a          157 c          125 g          109 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggcggttata actatgtctc ctggtaccaa cagcatgcag acacagcccc
      241 caaactcatg atttatgagg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattatttc tgctgctcac atgcaggcag tgattttttc gtcttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006030             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:17182:11590
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006030
VERSION     KCWK01006030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17182:11590"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..332
                     /note="immunoglobulin light chain variable region"
     V_region        8..332
     V_segment       8..295
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <257..>304
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71768.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       297..332
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        333..>370
                     /gene="IGLC"
BASE COUNT           74 a          119 c           97 g           80 t
ORIGIN      
        1 acatggggtg ctgacacagc cgccctcagt gtctggggcc ccagggcaga gggtcaccat
       61 ctcctgcact gggagcagct ccaacattgg aggttattat atatcctggt accagcagct
      121 cccaggaacg gcccccaaac tcctcgtcta tgacaataat aagcgaccct caggggtttc
      181 tgaccgattc tctggctcca agtctggttc ctcagccacc ctgaccatca ctgggctcca
      241 gactgaggat gaggctgatt attactgcca gtcctatgac agcagtctga gtgctcgggt
      301 attcggcgga gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac
      361 tctcttcccg
//
LOCUS       KCWK01006031             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:27187:11904
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006031
VERSION     KCWK01006031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:27187:11904"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..431
                     /note="immunoglobulin light chain variable region"
     V_region        98..431
     V_segment       98..394
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71769.1"
                     /translation="DYYCQTWDTGIVSF"
     J_segment       395..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           86 a          158 c          122 g          103 t
ORIGIN      
        1 acatggggga gagccctgag gagtctgcac catggcctgg accccaatcc tcctcctcct
       61 cctcactctc ctccttcact gcacagggtc tctctcccag cctgtgctga ctcagtcgcc
      121 ctctgcctct gcctccctgg gagcctcggt caagctcacc tgtactctga gcagtggaca
      181 cagcagctac accatcgcat ggcatcagca ccagcaaggg aaggcccctc ggtatttgat
      241 gtggcttaaa agtgatggca gccacagcaa gggggacggg atccctgatc gcttctcagg
      301 ctccagttcc ggggctgagc gctacctcac catctccaat ttccagtctg aggatgaggc
      361 tgattattac tgtcagacct gggatactgg cattgtgtca ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006032             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:4409:15874
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006032
VERSION     KCWK01006032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:4409:15874"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71770.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          147 c          130 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcggcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006033             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:12700:11779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006033
VERSION     KCWK01006033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12700:11779"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..434
                     /note="immunoglobulin light chain variable region"
     V_region        86..434
     V_segment       86..396
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71771.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       400..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           91 a          160 c          118 g          103 t
ORIGIN      
        1 acatggggga gaggtagccg tgtccaccat ggccctgact cctctcctcc tcctgctcct
       61 ctctcactgc acaggttccc tctcccagcc tgtgctgact cagccaccct ccctgtctgc
      121 atccccggga gcatcggcca gactcccctg caccctgagc actgacctca gtgttggtgg
      181 taaaaacatg tactggtacc agcagaagcc aggaagcgct cccaggttat tgctgtatta
      241 ccactccgac tcagacaagc agctgggacc tggggtcccc aatcgagtct ctggctccaa
      301 ggagacctca agtaacacag cgtttttgct catctctggg ctccagcctg aggacgaggc
      361 cgattattac tgtcaggtgt atgacagtag tgccaacacg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01006034             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:15902:4172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006034
VERSION     KCWK01006034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15902:4172"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    185..409
                     /note="immunoglobulin light chain variable region"
     V_region        185..409
     V_segment       185..373
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71772.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       377..409
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           88 a          134 c          138 g           87 t
ORIGIN      
        1 acatgggggg cgccggcggc tttggtgact ctagataacc tcgggccgat cgcacgcccc
       61 ccgtggcggc gacgacccat tcgaacgtct gccctatcaa ctttcgatgg tagtcgccgt
      121 gcctaccatg gtgaccacgg gtgacgggga atcagggttc gattccggag agggagcctg
      181 agaaacggct accagcagaa gccaccgcag ggccctgtat tggtcatctt tgctgatagt
      241 aaacggccct cagggatccc tgagcgattc tctggctcca actcagggaa caccgccacc
      301 ctgaccatca gcagggtcga ggccggggat gaggctgact attactgtca ggtttgggac
      361 agtagtagta aatggatatt cggcgggggg acccggctaa ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01006035             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:15870:8393
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006035
VERSION     KCWK01006035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15870:8393"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    60..384
                     /note="immunoglobulin light chain variable region"
     V_region        60..384
     V_segment       60..347
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <309..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71773.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       350..384
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>422
                     /gene="IGLC"
BASE COUNT           80 a          128 c          121 g           93 t
ORIGIN      
        1 acatgggcgg gacccttctc ctcctcggcc tccttgctca ctttacaggc tctgtggcct
       61 cctatgagtt gcctcagcca cgctcagtgt ccgtgtcccc aggacagacg gccaggatca
      121 cctgtggggg agacaacatt ggaagtaata gtgtgcattg gtaccagcag aagccaccgc
      181 gggcccctgt attggtcatc tctgttgata gcgaacggcc ctcagggatc cctgagcgat
      241 tctctggttc cagatcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg
      301 atgaggctga ctattactgt caggtgtggg ataatattta taaatacgcg gtattcggcg
      361 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      421 cg
//
LOCUS       KCWK01006036             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:16703:9633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006036
VERSION     KCWK01006036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:16703:9633"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71774.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           81 a          156 c          128 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttatg atggcgtctc ctggtaccag cagcactcag ggacagcccc
      241 cagactcctg atttatgatg tcactaagcg gccctcaggg gtctcggatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctcac catctctggg ctccagactg aggacgaggc
      361 tgattattat tgttgctcat ataggagtgg aaacacttgg ctattcggcg gaggggcccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01006037             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:3004:15946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006037
VERSION     KCWK01006037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:3004:15946"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..381
                     /note="immunoglobulin light chain variable region"
     V_region        89..381
     V_segment       89..344
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <309..>353
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71775.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       347..381
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        382..>419
                     /gene="IGLC"
BASE COUNT           84 a          141 c          109 g           85 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcgtctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg ggcagacggt caccatctcc tgtacccgca
      121 gcagaggcaa cattgacaat agttatgtgc agtggtacca gcagcgcccg ggcagtgccc
      181 cgaccacagt gatttacaga gataaccaaa gagcctctgg ggtccctgat cggttctctg
      241 gctccatcga cagctcctcc aactctgcct ccctcaccat ctctgggctg aagtctgagg
      301 acgaggctga ctactactgt cagtctactg atggcaacta caatcggtta ttcggaggag
      361 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006038             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:10508:15365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006038
VERSION     KCWK01006038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10508:15365"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71776.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          149 c          130 g           96 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggcgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006039             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:25625:19985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006039
VERSION     KCWK01006039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:25625:19985"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71777.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       399..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          157 c          122 g          105 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa cagcatccag gcacagcccc
      241 caaagtcatg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctagg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat atacaggcat caacagttac atcttcggtg gtgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01006040             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15419:16107
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006040
VERSION     KCWK01006040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15419:16107"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71778.1"
                     /translation="DYYCQVWDIYIDHPVLF"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           92 a          142 c          130 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggag gagacaacat
      181 tggaagtgaa gttgtcaact ggtaccagca gaagccaccg caggcccctg tgctggtcat
      241 ctatgctgat tatgaacggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggagt cgacgccggg gatgaggctg actattattg
      361 tcaggtgtgg gacatttata ttgaccatcc ggttttattc ggaggaggga cccgactgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01006041             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:9405:18899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006041
VERSION     KCWK01006041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:9405:18899"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71779.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       408..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          155 c          131 g          110 t
ORIGIN      
        1 acatgggggg ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg gttcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agcatctggg gcccccggac agaggattac catctcctgc
      181 actgggacca ggtccaacat cggggcgggt ttttatgtgt cctggtacca gcagttccct
      241 gggacagccc ccaaactcct catctttgaa aataataagc gaccctcagg gctttctgac
      301 cgattctctg gctccaagtc tgggtcctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgctcatca tgggaaagca gcctgaattg ggtattcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01006042             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:21913:4637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006042
VERSION     KCWK01006042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:21913:4637"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..451
                     /note="immunoglobulin light chain variable region"
     V_region        118..451
     V_segment       118..414
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <382..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71780.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       415..451
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT           84 a          170 c          129 g          106 t
ORIGIN      
        1 acatggggct gcagtgtggc tgcctcagca gagccctgag gagtctgcac catggcctgg
       61 accccaatcc tcctcctcct cctcactctc ctccttcact gcacagggtc tctctcccag
      121 cctgtgctga ctcagtcgcc ctctgcctct gcctccctgg gagcctcggt caagctcacc
      181 tgcactctga gcagtggcca ctacagctac accatcgcat ggcatcagca gcagcaaggg
      241 aaggcccctc ggttcttgat gtggcttaag agtgatggca gccacaccaa gggggacggg
      301 gtccctgatc gcttctcagg ctccagctcc ggggctgagc gctacctcac catctccaac
      361 ctccagtctg aggatgaggc tgattattac tgtcagacct gggatattgg catttgggta
      421 ttcggcggag ggacccggct aaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCWK01006043             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:19940:5486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006043
VERSION     KCWK01006043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19940:5486"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71781.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gattcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tatttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006044             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:26100:8933
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006044
VERSION     KCWK01006044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:26100:8933"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..388
                     /note="immunoglobulin light chain variable region"
     V_region        58..388
     V_segment       58..351
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <316..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71782.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       352..388
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           83 a          139 c          106 g           98 t
ORIGIN      
        1 acatgggggg atctgctcct cttcaccctc ctcactcagg gcacaggatc ctgggctcag
       61 gctgccctga ctcagcctcc ctcaatgtct gggtctcctg gacagtcggt caccatctcc
      121 tacactggaa ccagcagtga cattggtggt tataaccgtg tctcctggta ccaacagcac
      181 ccaggcaaag accccaaatt catgatttat gaggtcagtc aacggccctc aggggtctct
      241 gatcgtatct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag
      301 actgaggatg aggctggtta ttactgcagc tcatttgcag gtaccaacac tggcttaatc
      361 ggtggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      421 ttcccg
//
LOCUS       KCWK01006045             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:14465:7245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006045
VERSION     KCWK01006045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14465:7245"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71783.1"
                     /translation="DYYCQLYDTSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          165 c          118 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccggggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca aacagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcaac tatatgacac tagtactaat gtgttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01006046             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:21438:8261
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006046
VERSION     KCWK01006046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21438:8261"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71784.1"
                     /translation="DYYCAIGHNSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          161 c          114 g          107 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 ctgcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctgcctacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatacaaatc agactcagat aaggaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ctcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ctactgtgcc attgggcaca acagcggtga ttacatcttc gctgctggga
      421 cccgcctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01006047             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:10611:11099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006047
VERSION     KCWK01006047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10611:11099"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..389
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71785.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       396..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           84 a          156 c          116 g          115 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcgctct caggacttct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaagctgc cccgactcag
      121 cctccctctg tgtccgggtc tcctggacag tcggtcacct tctcctgcac tggaaccggc
      181 agtgattttg ggtcttataa tgctgtgtct tggtaccaac agcatccagg caaagccccc
      241 caactcataa tttttgaggt caataagcgg ccctcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccaggctga ggatgaggct
      361 gattattact gctgctcata tgtaggcagc aacacttaca tcttcgatgt tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01006048             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:13591:15260
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006048
VERSION     KCWK01006048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13591:15260"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71786.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           89 a          152 c          120 g          112 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agactccctc tgtgtccggg tctcctggac attcggtcac catctcctgc actggaacca
      181 gcagtgatat tgggtattat catgctgtgt cttggtacca gcatcatcca ggcaaagccc
      241 ccaaactcat gatttatgag gtcaataaac ggcccgcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccagact gaggatgagg
      361 ctgattatta ctgtagctca tatgcaggca gcaacagttt attcttcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006049             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10665:11494
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006049
VERSION     KCWK01006049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10665:11494"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71787.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          156 c          127 g          107 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa cagtgtcgcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcaca gtgtatcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcatc tattatgatg atcaacgagc ctcgggtgtc tctgaccgat
      301 tctctggctc caggtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagaggttac atcttcggtg
      421 atgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01006050             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:12493:5654
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006050
VERSION     KCWK01006050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12493:5654"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..381
                     /note="immunoglobulin light chain variable region"
     V_region        102..381
     V_segment       102..349
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <312..>353
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71788.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       350..381
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        382..>419
                     /gene="IGLC"
BASE COUNT           83 a          129 c          116 g           91 t
ORIGIN      
        1 acatgggggt gggctcagaa gcagagctct ggggtgtctc caccatggcc tggactcctc
       61 tctggctcac cctcctcagt ctttgcacag gttctatggt ttcttctgag ctgactcagg
      121 accctgcagt gtctgtggcc ttgggacaga cagtcaggat tacctgccaa ggagacagcc
      181 tcagaagctc ttatgcaagc tggtaccaac agaggccagg cccctcaggg atcccagagc
      241 gattctctgg ctcctactca cgaaacacag cttccttgac catctctggg gctcaggtgg
      301 aagatgaggc tgactattac tgtgactcct gggacagcag cggaacccaa ttcggaggag
      361 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006051             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:10440:3397
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006051
VERSION     KCWK01006051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10440:3397"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..412
                     /note="immunoglobulin light chain variable region"
     V_region        101..412
     V_segment       101..387
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71789.1"
                     /translation="DYYCQSADSSGNDCLF"
     J_segment       392..412
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>462
                     /gene="IGLC"
BASE COUNT          105 a          136 c          132 g           89 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgacc tgacacagcc
      121 accctcagtg ccagtgtccc caggacagac ggccaggagc acctgctctg gagaagtagt
      181 ggcaaaaaaa tctggtcagt gggtccagca gaagccaggc caggcccctg tgttggagat
      241 tcataaagac agcgagaggc cctcagggat ccctgaccga ttccctaggt ccactccagg
      301 gacaaaagat accttgacca gcaggggggc caggcagaag atgaggctga ctattactgt
      361 caatcagcag acagcagtgg taatgattgt ctattcggcg gagggacccg gcaaagcgtc
      421 ctgggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01006052             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:10258:9867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006052
VERSION     KCWK01006052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10258:9867"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..343
                     /note="immunoglobulin light chain variable region"
     V_region        13..343
     V_segment       13..306
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <268..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71790.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       307..343
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>381
                     /gene="IGLC"
BASE COUNT           73 a          119 c          102 g           87 t
ORIGIN      
        1 acatgggggg cccagtctgt gctgacgcag ccgccctcag tgtctggggc gcccgggcag
       61 agggtcaccc tctcctgcac tgggagcagc tccaacattg gagattatta tgtgcagtgg
      121 taccagcagc ttccaggaac ggcccccaaa ctcctcatct atgaaaataa taagcgaccc
      181 tcaggggttt ctgatcgatt ctctggctcc cagtctggta cctcagcctc cctgaccatc
      241 actggactcc agtctgacga tgaggctgat tattactgtc agtcctatga tagcagcctg
      301 agtgctgtgt tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      361 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01006053             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:21877:6841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006053
VERSION     KCWK01006053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21877:6841"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71791.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          147 c          128 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01006054             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:9749:14814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006054
VERSION     KCWK01006054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9749:14814"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71792.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          140 c          137 g           99 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 gcaccctcga tttcagtgtc ccccggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atgtatgctg atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacatgaa tagtcatcat ctattattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006055             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:16834:17595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006055
VERSION     KCWK01006055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16834:17595"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71793.1"
                     /translation="DYYCCSRSSSSTYVF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           82 a          163 c          118 g          112 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac gttggtggtt ataactctgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaagtc atgatttttg gtgtcaataa tcggccctct ggggtctctg accgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagc ctgaggacga
      361 ggctgactat tactgttgtt cacgttcaag cagtagcact tacgtcttcg gtcctgggac
      421 ccggctcacc gtcctgggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01006056             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:16260:12619
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006056
VERSION     KCWK01006056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16260:12619"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71794.1"
                     /translation="DINCHSADSSGNHWVF"
     J_segment       389..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          102 a          132 c          127 g          102 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgttctg gagaaacact
      181 ggcaaaaaaa tatggtcagt ggttccagca gaagccaggc caggcccctg ttgtggtgat
      241 atataaggac agtgagaggc cctcagggat ccctgagcga ttctctaggt ccatttcagg
      301 gacaataatt accttgacca tctgtggggc cccggcagaa gatgaggctg acattaactg
      361 tcattcagca gacagcagtg gtaatcattg ggtcttcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006057             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:19039:15124
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006057
VERSION     KCWK01006057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19039:15124"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71795.1"
                     /translation="DYYCQVWDISSEHVLF"
     J_segment       392..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          141 c          137 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagc ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcggtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaggtgca gttgtgaatt ggtaccacca gaagccaccg caggcccctg tactggtcat
      241 ctatgctgat agcgatcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattagta gtgaacatgt attattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006058             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:9298:12800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006058
VERSION     KCWK01006058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:9298:12800"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71796.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          157 c          124 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat aatgtgtcct ggtaccagca cctcccagga
      241 acagctccca aactcctcat ctattataat gatcaacgag gctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggcgg attattactg cgcagcgtgg gatgatagcc tgagcagtta catcttcgct
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01006059             444 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:16739:14212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006059
VERSION     KCWK01006059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 444)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16739:14212"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..406
                     /note="immunoglobulin light chain variable region"
     V_region        88..406
     V_segment       88..374
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>378
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71797.1"
                     /translation="DYYCDSWDSSGTQF"
     J_segment       375..406
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>444
                     /gene="IGLC"
BASE COUNT           88 a          139 c          119 g           98 t
ORIGIN      
        1 tcagaagcag agctctgggg tgtctccacc atggcctgga ctcctctctg gctcaccctc
       61 ctcagtcttt gcacaggttc tatggtttct tctgagctga ctcaggaccc tgcagtgtct
      121 gtggccttgg gacagacagt caggattacc tgccaaggag acagcctcag aagctcttat
      181 gcaagctggt accaacagag gccaggccag gcccctgtgc tggtcgtcta tggtaacaac
      241 taccggccct cagggatccc agagcgactc tctggctcct actcacgaaa cacagcttcc
      301 ttgactatct ctggggctca ggtggaagat gaggctgact attactgtga ctcctgggac
      361 agcagcggaa cccaattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct
      421 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01006060             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:8815:12323
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006060
VERSION     KCWK01006060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:8815:12323"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71798.1"
                     /translation="DYYCSSYAGSNILFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          151 c          120 g          112 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtggtatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag taatatttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01006061             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:17712:18663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006061
VERSION     KCWK01006061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17712:18663"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..295
                     /note="immunoglobulin light chain variable region"
     V_region        7..295
     V_segment       7..256
                     /gene="IGLV1-68"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <220..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71799.1"
                     /translation="DYYCGAWDSSLSGYIF"
     J_segment       258..295
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        296..>333
                     /gene="IGLC"
BASE COUNT           68 a          103 c           86 g           76 t
ORIGIN      
        1 acatgggggc agaaggtcac catctcctgc tctggaagta gctccaacat cgggagaaat
       61 tctgtctcct ggtaccagca ggtcccagga acggccccca aactcctcac ctatgacaat
      121 gataagcgac cctcaggggt ttctgaccga ttctctggct ccaagtctgg ttcctcagcc
      181 tccctggcca tcactggact ccagactgga gatgaggctg attattactg cggagcatgg
      241 gatagcagtc tgagtggtta cattttcggt gctgggaccc ggctcaccgt cctaggtcag
      301 cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01006062             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:23349:12534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006062
VERSION     KCWK01006062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23349:12534"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..456
                     /note="immunoglobulin light chain variable region"
     V_region        126..456
     V_segment       126..419
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <381..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71800.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       420..456
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           93 a          158 c          127 g          116 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca cttcacagtt ccagggtcct
      121 gggcccagtc tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca
      181 ccatctcctg cactgggagc agctccaaca ttggagatta ttttgtgcag tggtaccagc
      241 accttccagg aacggccccc aaactcctca tctatgaaaa taataagcgg ccctcaggga
      301 tttctgatcg attctctggc tcccagtctg gaacctcagc ctccctgacc atcactggac
      361 tccagtctga ggatgaggct gattattact gccagtccta tgacagcagt ttgattgctg
      421 tgttattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      481 tcactctctt cccg
//
LOCUS       KCWK01006063             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:28508:12701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006063
VERSION     KCWK01006063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:28508:12701"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71801.1"
                     /translation="DYYCQVWDSSSKYVLF"
     J_segment       392..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          138 c          141 g           98 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgc ggcctcctat gaggtgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taaaagtgtg cagtggtacc agcagacgcc accgcaggcc cctgtactgg
      241 tcatttatgg tgatagggaa cggccctcag ggatccctga gcgattctct ggttccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggatagt agtagtaaat atgtgttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01006064             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:27049:11987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006064
VERSION     KCWK01006064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:27049:11987"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71802.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       396..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           94 a          150 c          117 g          108 t
ORIGIN      
        1 acatgggggg gagccaggga tcccttccaa tatcagcacc atggcctgga ctctgctcct
       61 cctccagttc ctcctcactt gctgcccagg gtccaattct caggctgtag tgactcagga
      121 gccctcaatg actgtgtccc caggagggac agtcactctc acctgtgctt ccagcactgg
      181 agcagtcacc agtggtcact ctccacactg gttccagcag aaacctggac aagcccccaa
      241 gacactgatt tataatacaa actacagaca ctcctggact cctgcccggt tctcaggctc
      301 cctccttggg ggtaaagctg ccctgacact gtcaggtgcg cagcctgagg atgaggctga
      361 gtattattgt ttactgtact atagtggtgc tcagctgtta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006065             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:4003:14810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006065
VERSION     KCWK01006065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4003:14810"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..442
                     /note="immunoglobulin light chain variable region"
     V_region        97..442
     V_segment       97..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71803.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          164 c          110 g          112 t
ORIGIN      
        1 acatgggggc ccactgcagg gaaagaggct gtgtccacca tggcctggac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctcccagc ctgtgctgac ccagccaacc
      121 tccctctcag catctccggg aacatcagcc agactcagct gcaccttgag cagtggcaat
      181 gttggtagtt acagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
      241 ctttactact actcagactc aagtaaccac caggactctg gagtccccag ccgcttctct
      301 ggatcgaaag atgcttcagc caatgcaggg cttttactga tttctgggct ccagtctgaa
      361 gatgaggctg actattactg tgccacatgg cacagcagcg cttcttacat cttcggtcct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01006066             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:20770:19966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006066
VERSION     KCWK01006066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20770:19966"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71804.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          152 c          120 g          111 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt ggttattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01006067             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:17307:15342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006067
VERSION     KCWK01006067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17307:15342"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71805.1"
                     /translation="DYYCCSYRSGNTWLF"
     J_segment       398..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           82 a          157 c          126 g          106 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcgctct cgggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcagtctgc cctgactcag
      121 cctccctcag tgtccaagtc tcttggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgacattg gtggttatga tggcgtctcc tggtaccagc agcactcagg gacagccccc
      241 agactcctga tttatgatgt cactaagcgg ccctcagggg tctcggatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctcacc atctctgggc tccagactga ggacgaggct
      361 gattattact gttgctcata taggagtgga aacacttggc tattcggcgg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01006068             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:13721:12358
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006068
VERSION     KCWK01006068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13721:12358"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71806.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       414..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          162 c          123 g          111 t
ORIGIN      
        1 acatggggtg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctaa tgtcttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01006069             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:13190:9283
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006069
VERSION     KCWK01006069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13190:9283"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..385
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71807.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       394..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           91 a          151 c          116 g          104 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gcatctgggg cccccggaca gagggtcacc atctcctgca ttagcagcag ctccaacatc
      181 ggggcggctt attatgtatc ctggtaccaa cagttcccag gaacagcccc caaactcctc
      241 atctttgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggtccctcag cctccctgac catcactgga ctccaatctg aggatgaggc tgattattac
      361 tgtttagcat gggataccag cctgaattgg atcttcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01006070             391 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:20593:18978
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006070
VERSION     KCWK01006070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 391)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20593:18978"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    29..349
                     /note="immunoglobulin light chain variable region"
     V_region        29..349
     V_segment       29..310
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <278..>325
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71808.1"
                     /translation="DYFCQVWDSGSDHYIF"
     J_segment       316..349
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>391
                     /gene="IGLC"
BASE COUNT           78 a          121 c          111 g           81 t
ORIGIN      
        1 acatgggcac tgcacaggct ctgcgacctc ctatgagttg actcagccac cctcggtgtc
       61 agcggcctct ggacagacgg ccaggatcac ctgtggggga gacaacattg gaactacata
      121 tgtgcactgg taccagcaga agccaccaca ggcccctgtg caggtcatct ttgctgatag
      181 caaacggccc tcaggggtcc ctgaccgatt ctctggctcc aactcaggga acaccgccac
      241 cctgaccatc agcggggtcg aggccgggga tgaggctgac tatttctgtc aggtgtggga
      301 cagtggtagt gatcattaca tcttcggtgt tgggacccgg ctcaccgtct taggtcagcc
      361 caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01006071             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:15808:18930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006071
VERSION     KCWK01006071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15808:18930"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..378
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71809.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       380..416
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>433
                     /gene="IGLC"
BASE COUNT           88 a          132 c          123 g           90 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacttttc tcctcctcgg
       61 cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc caccctcggt
      121 gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca ttggaagtca
      181 aagtgtgcac tggtaccagc acaagccacc gcaggcccct gttctggtca tcttttatta
      241 taccgaatgg ccctcaggaa tccctgagcg aatctctggc tccaaatcag ggaacaccgc
      301 caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg
      361 ggacacaagt cttgatcacg gcttattcgg aggagggacc cggctgaccg tcctaggtca
      421 gcccaaggct gcc
//
LOCUS       KCWK01006072             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:11833:16662
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006072
VERSION     KCWK01006072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11833:16662"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71810.1"
                     /translation="DYYCAVWDDSLTGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          158 c          120 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtcac catctcctgt
      181 tctggaagca gttccaacat cggaagtaac agtgtatcct ggtaccaaca actcccagaa
      241 acgactccca aactcctcat ctattataat catcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacttcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagtatgg gatgatagcc tgaccggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01006073             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:25385:8866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006073
VERSION     KCWK01006073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25385:8866"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71811.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          148 c          127 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtggga cagacaacat
      181 tggaagtcaa agtgtgcact ggtaccagca caagccaccg caggcccctg tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006074             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:22597:16907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006074
VERSION     KCWK01006074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22597:16907"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..434
                     /note="immunoglobulin light chain variable region"
     V_region        86..434
     V_segment       86..397
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71812.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       398..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           91 a          159 c          110 g          112 t
ORIGIN      
        1 acatgggggg aaagaggctg tgtccaccat ggcctggact cctctcctcc tcctgctcct
       61 ctctcactgc acaggttccc tctcccagcc tgtgctgacc cagccaacct ccctctcagc
      121 atctccggga gcatcagcca gactcagctg caccttgagc agtggcatca atgttggtag
      181 ttacagcata ttctggtacc agcagaagcc agggagtcct ccccggtacc ttctgtacta
      241 ctactcagac tcaagtaaac accagggctc tggagtcccc agccgcttct ctggatccaa
      301 agatgcttcg gccaatgcag gccttttagt gatctctggg ctccagtctg aagatgaggc
      361 tgactattac tgtgccatat ggcacagcag cgcttcttac ttcttcggta ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01006075             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:24137:10718
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006075
VERSION     KCWK01006075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24137:10718"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71813.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       410..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          160 c          124 g          108 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctcgtctc ctctcctcct cacccttttc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacac agccgccctc agtgtctggg gccccagggc agagggtcac catctcctgc
      181 actgggagca gctccaacat tggaggttat tatatatcct ggtaccagca gctcccagga
      241 acggccccca aactcctcgt ctatgacaat aataagcgac cctcaggggt ttctgaccga
      301 ttctctggct ccaagtctgg ttcctcagcc accctgacca tcactgggct ccagactgag
      361 gatgaggctg attattactg ccagtcctat gacagcagtc tgagtgctcg ggtattcggc
      421 ggagggaccc ggctaaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01006076             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:3170:11329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006076
VERSION     KCWK01006076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:3170:11329"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..427
                     /note="immunoglobulin light chain variable region"
     V_region        101..427
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71814.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       395..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>469
                     /gene="IGLC"
BASE COUNT           86 a          152 c          124 g          107 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtctccatc tcctgttctg gaagcagctc
      181 caacatcgga agtcatagtg tctcctggta ccagcagctc ccaggaacag ctcccaaact
      241 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctctca
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag gccgaggatg aggctgatta
      361 ttactgcgca gcatgggatg atagtctgag cggttacatc ttcggtgctg ggacccggct
      421 cgccgtcgta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01006077             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:9840:10774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006077
VERSION     KCWK01006077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:9840:10774"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..451
                     /note="immunoglobulin light chain variable region"
     V_region        121..451
     V_segment       121..414
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71815.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       415..451
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT           92 a          157 c          124 g          116 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcacttca cagttccagg gtcctgggcc
      121 cagtctgtgc tgacgcagcc gccctcagtg tctggggcgc ccgggcagag ggtcaccatc
      181 tcctgcactg ggagcagctc caacattgga gattattttg tgcagtggta ccagcacctt
      241 ccaggaacgg cccccaaact cctcatctat gaaaataata agcgaccctc agggatttct
      301 gatcgattct ctggctccca gtctggaacc tcagcctccc tgaccatcac tggactccag
      361 tctgaggatg aggctgatta ttactgccag tcctatgaca gcagtttgat tgctgtgtta
      421 ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCWK01006078             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:16689:11747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006078
VERSION     KCWK01006078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16689:11747"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71816.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          148 c          129 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgtactggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaac tattgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006079             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:22876:16378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006079
VERSION     KCWK01006079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22876:16378"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71817.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          143 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagcc ggccaggatc acctgctctg gagatgtatt
      181 accaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tattggtcat
      241 ctctgaggac accgaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtcatggctt cttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01006080             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:15640:17626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006080
VERSION     KCWK01006080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15640:17626"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71818.1"
                     /translation="DYYCAAWDSSLSSPVF"
     J_segment       393..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          150 c          122 g          107 t
ORIGIN      
        1 acatggggtc agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgta
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctctt gttctggaag catctccagc
      181 attggaagta gtgatgtatg ttggtaccag caactcccag gaacggcccc caaactcctc
      241 atcaattata gtgatcagcg actctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcct gggatagcag cctgagcagt ccggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006081             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:18088:8012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006081
VERSION     KCWK01006081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:18088:8012"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..413
                     /note="immunoglobulin light chain variable region"
     V_region        92..413
     V_segment       92..379
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71819.1"
                     /translation="DYYCQVWGVTSDHPLF"
     J_segment       382..413
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>454
                     /gene="IGLC"
BASE COUNT           89 a          142 c          128 g           95 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacttttc tcctcctcgg
       61 cctccttgct tactgcacag actctgcggc ctcctatgat ctgactcagc caccctcggt
      121 gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca ttggaagtga
      181 agttgttaac tggtaccagc agaagccacc gcaggcccct gtcctggtca tctatgctaa
      241 taacgaacgg ccctcaggga tccctgagcg attctctggc tccaaaccat ggaacacggc
      301 caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg
      361 gggcgttact agtgatcatc ccttattcgg aggagggacc cggctgaccg tccaaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01006082             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:7170:6757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006082
VERSION     KCWK01006082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7170:6757"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71820.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           94 a          142 c          133 g           92 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgaa ctgactcagt
      121 caccctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca
      181 ttggaattaa aactgtacac tggtaccagc agaagccacc gcagggccct gtattggtca
      241 tctttgctga tagtaagcgg cccacaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01006083             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:21967:11980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006083
VERSION     KCWK01006083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21967:11980"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71821.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          162 c          122 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tactaaaaac atgtactggt acctacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaaagaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01006084             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:17173:13822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006084
VERSION     KCWK01006084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17173:13822"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..266
                     /note="immunoglobulin light chain variable region"
     V_region        8..266
     V_segment       8..229
                     /gene="IGLV3-117"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71822.1"
                     /translation="DYYCKSWDSSGTHYIF"
     J_segment       230..266
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           67 a           91 c           80 g           66 t
ORIGIN      
        1 acatgggcaa ggagacagcc tcaaaaccta ttatgcaagc tggtaccagc agaagccagg
       61 ccaggtccct gtgctggtca tctatggtaa caactaccgg ccctcaggga tcccaggccg
      121 attctctgtc tcctggtcag gaaacacagg ttccttgacc atcactgcgg ctcaggtgga
      181 agatgaggct gactattatt gtaagtcctg ggacagcagt ggtacccatt acatcttcgg
      241 tggtgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      301 cccg
//
LOCUS       KCWK01006085             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:7095:13488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006085
VERSION     KCWK01006085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7095:13488"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71823.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       388..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           93 a          142 c          130 g           93 t
ORIGIN      
        1 acatgggggt ctcaggaggc agcattgacg gtgcctcagc catggcctgg acccttctcc
       61 tcctcggcct cctcgcttac tgcacaggct ctgcgacctc ctatgaattg actcagtcac
      121 cctcagtgtc agcggcctca ggacagccgg ccaggatcac ctgtggggga gacaacattg
      181 gaactaaaac tgtgcactgg taccaacaga agccaccgca gggccctgta ttggtcatct
      241 ttgctgatag tagacggccc tcagggatcc ctgagcgatt ctctggctcc aactcaggga
      301 acaccgccac cctgaccatc agcagggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cagtagtagt aaatggatat tcggcggggg gacccggcta accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01006086             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:17950:3652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006086
VERSION     KCWK01006086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17950:3652"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71824.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          156 c          128 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgagtc agcctccctc agcgtctgag gccgccagga agagtgtctc catctcctgt
      181 tctggaagca gctccaacat cggaagtcat agtgtctcct ggtaccagca gctcccagga
      241 acagctccca aactcctcat ctattatagt gatcaacgag cctcaggtgt ctctgaccga
      301 ttctctggct ctcagtctgg cacgtcagcc tccctggcca tcagtgggct ccaggccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagtc tgagcggata catcttcggt
      421 gctgggaccc ggctcgccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01006087             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:12208:6379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006087
VERSION     KCWK01006087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:12208:6379"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..396
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71825.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       398..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           94 a          151 c          117 g          109 t
ORIGIN      
        1 acatggggtc tggagccagg gatcccttcc aatatcagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcacctgtgc ttccagcact
      181 ggagcagtca ccagtggtca ctctccacac tggttccagc agaaacctgg acaagccccc
      241 aagacactga tttataatac aaactacaga cacgcctgga ctcctgcccg gttctcaggc
      301 tccctccttg ggggtaaagc tgccctgaca ctgtcaggtg cgcagcctga ggatgaggct
      361 gagtattatt gtttactgta ctatagtggt gctcagctgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01006088             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:8896:12859
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006088
VERSION     KCWK01006088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8896:12859"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71826.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          158 c          129 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccgggaa gagtgtctcc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtcata gtgtctcctg gtaccagcag ctcccaggaa
      241 cagctcccaa actcctcgtc tattatagtg atcaacgagc ctctggtgtc tctgaccgat
      301 tctctggcgc tcagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg atgatagcct gagcggttac atcttcggtg
      421 ctgggacccg gctcgccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01006089             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:26220:14276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006089
VERSION     KCWK01006089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:26220:14276"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71827.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          162 c          121 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcaatattg gcaataaaaa catgtactgg taccagcaga agccagggag cgctcccaag
      241 ttattcctgt actactactc cgactcagac atgcggctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtcat acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctgt attattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01006090             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:16356:12615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006090
VERSION     KCWK01006090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16356:12615"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71828.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       392..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          144 c          132 g           93 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc ttactgcaca ggctctgcga cctcctatga actgactcag
      121 tcaccctcag tgtcagcggc ctcaggacag ccggccagga tcacctgtgg gggagacgac
      181 attggaacta aaactgtaca ctggtaccag cagaagccac cgcagggccc tgtattggtc
      241 atctttgctg atagtaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatgg atattcggcg gggggacccg gctaaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01006091             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:6599:13897
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006091
VERSION     KCWK01006091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:6599:13897"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..287
                     /note="immunoglobulin light chain variable region"
     V_region        7..287
     V_segment       7..251
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71829.1"
                     /translation="DYYCSSYTGINSYIF"
     J_segment       252..287
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>325
                     /gene="IGLC"
BASE COUNT           68 a          103 c           80 g           74 t
ORIGIN      
        1 acatggggtc accatctcct gcactggaac cagcagtgac atcggtggtt ataactatgt
       61 ctcctggtac caacagcatc caggcacagc ccccaaagtc atgatttatg aggtcagtaa
      121 gcggccctca ggggtctctg atcgcttctc tggctccaag tctggcaaca cggcctccct
      181 gaccatctct gggctccagg ctgaggacga ggctgattat tactgcagct catatacagg
      241 catcaacagt tacatcttcg gtggtgggac ccggctcacc gtcctaggtc agcccaaggc
      301 ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01006092             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:16789:13458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006092
VERSION     KCWK01006092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16789:13458"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71830.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       396..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          142 c          144 g           91 t
ORIGIN      
        1 acatgggggg ggggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgcg ggggagacaa
      181 gattggaagt gaagttgtga actggtacca gaagaagcca gcgcaggccc ctgcactggt
      241 catctatgct gatagcgaac ggccctcagg gatccctgag cgattctctg gctccaaatc
      301 agggaacacg gccaccctga ccatcagggg ggtcgaggcc gggggtgagg ctgactatta
      361 ctgtcaggtg tgggacatgc gtagtgatca accgctattc ggcggaggga cccggctaac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01006093             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:14246:8224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006093
VERSION     KCWK01006093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14246:8224"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..453
                     /note="immunoglobulin light chain variable region"
     V_region        117..453
     V_segment       117..410
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71831.1"
                     /translation="DYYCSAWDSSLSINYIF"
     J_segment       416..453
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           96 a          158 c          124 g          113 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac atcggggcgg gttattatgt atcctggtac cagcagttcc
      241 caggaacagc ccccaaactc ctcatctatg agaataataa acgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatcacc ggactccaat
      361 ctgaggatga gtctgattat tattgctcag catgggatag cagcctgagt atcaattaca
      421 tcttcggttc tgggacccgt ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      481 ctctgttccc g
//
LOCUS       KCWK01006094             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:15057:7491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006094
VERSION     KCWK01006094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15057:7491"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71832.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          162 c          120 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006095             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:7756:15208
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006095
VERSION     KCWK01006095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:7756:15208"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71833.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       395..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           85 a          149 c          136 g           93 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcggcc tcctatgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc ccctgtgggg gagacaacat
      181 tggaactaaa tatgtgcact ggtaccagca gaagccagcg caggcccctg tgttggtcat
      241 ctatgctgat accagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccgga tatgaggctg actatttctg
      361 tcaggtgtgg gacgatagta gtgatcatcc ggttttcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006096             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:19656:17786
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006096
VERSION     KCWK01006096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:19656:17786"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71834.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           97 a          159 c          110 g          110 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacagtt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcaactcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ttgcctacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 gttacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaaaatgg ttcaacaaac acaggcattt tacacatctc tgggctccag tctgaggatg
      361 aggctgacta tttctgtgcc attggacaca gcagcggtcc ttacatcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01006097             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:20836:3613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006097
VERSION     KCWK01006097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20836:3613"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71835.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          140 c          138 g           99 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 ggcaccctcg atttcagtgt cccccggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt gaagttgtga actggtacca gcagaagcca ccgcaggccc ctgtgttggt
      241 catgtatgct gatagcgagc ggccctcagg gatccctgag cgattctctg gctccaaatc
      301 agggaacacg gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacatga atagtcatca tctattattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01006098             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:26648:14997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006098
VERSION     KCWK01006098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:26648:14997"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71836.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          141 c          136 g          102 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgt ggcctcctat gagttgcctc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taatagtgtg cattggtacc agcagaagcc accgcgggcc cctgtattgg
      241 tcatctctgt tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccagat
      301 cagggaacac cgccaccctg accatcagcg gggtcaaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggataat atttataaat acgcggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01006099             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:25447:14693
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006099
VERSION     KCWK01006099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:25447:14693"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71837.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc ttcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaaataaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006100             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:10564:10129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006100
VERSION     KCWK01006100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10564:10129"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71838.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       394..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          153 c          118 g          104 t
ORIGIN      
        1 acatgggggg tacagaaggc aggactcagg acaatctcca gcatggcctg gttccctctc
       61 gtcctcaccc tcctcactca ctgtgcaggg tcctgggccc agtctgtgct gactcagcct
      121 ccctcagcgt ctgaggccgc caggaagagt gtcaccatct cctgttctgg aagcagctcc
      181 aacatcggaa gtaataatgt gtcctggtac cagcacctcc caggaacagc tcccaaactc
      241 ctcatctatt ataatgatca acgaggctca ggtgtctctg accgattctc tggctccaag
      301 tctggcacgt cagcctccct ggccatcagt gggctccaga ccgaggatga ggctgattat
      361 tactgcgcag cgtgggatga tagcctgagc agttacatct tcgctgctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01006101             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:18038:2382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006101
VERSION     KCWK01006101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18038:2382"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..296
                     /note="immunoglobulin light chain variable region"
     V_region        8..296
     V_segment       8..259
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <221..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71839.1"
                     /translation="DYYCAAWDDSLRGYIF"
     J_segment       260..296
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>334
                     /gene="IGLC"
BASE COUNT           70 a          102 c           86 g           76 t
ORIGIN      
        1 acatgggagg aacagtgtcg ccatctcctg ttctggaagc agctccaaca tcggaagtca
       61 tagtgtatcc tggtaccagc agctcccagg aacagctccc aaactcctca tctattatga
      121 tgatcaacga gcctcaggtg tctctgaccg attctctggc tccaggtctg gcacgtcagc
      181 ctccctggcc atcagtgggc tccagaccga ggatgaggct gattattact gcgcagcatg
      241 ggatgatagc ctgagaggtt acatcttcgg tgatgggacc cggctcaccg tcctaggtca
      301 gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01006102             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:24120:10857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006102
VERSION     KCWK01006102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24120:10857"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71840.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          161 c          125 g          109 t
ORIGIN      
        1 acatggggct cattcctggc tgtggctcag gaagcagagc ctggagcatc tccaccatgg
       61 cctgggctcc actcctcctc accctcctcg ctcactgcac agggtcttgg gctgaggttg
      121 tgttcactca gccccattct gtgtcggggt ctccggggca gacggtcacc atctcctgca
      181 cccgcagcag tggcagcatt gacaacggct ttgtgtactg gtaccagcag cggccgggca
      241 gcgctcccac cactgtgatt tacaaagata accaaagacc ctctggggtc cctgatcggt
      301 tctctggctc catcgacagc tcctccaact ctgcctccct caccatctct ggactgaaat
      361 ctgaggacga ggctgactat tactgtcagt cttatgacag cagcagtgta ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006103             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:18495:18229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006103
VERSION     KCWK01006103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18495:18229"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71841.1"
                     /translation="DYYCSSWESSLIWVF"
     J_segment       407..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          153 c          130 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaacatc ggggcgggtt tttatgtatc ctggtaccag cagttcccag
      241 ggacagcccc caaactcctc atctttgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag cctccctgac catcactgga ctccaatctg
      361 aggatgaggc tgattattat tgttcatcat gggaaagcag cctgatttgg gttttcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006104             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:19916:10079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006104
VERSION     KCWK01006104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19916:10079"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71842.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          162 c          124 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcggg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006105             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:5633:6114
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006105
VERSION     KCWK01006105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:5633:6114"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71843.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          164 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccccctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca aacagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006106             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:27648:12147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006106
VERSION     KCWK01006106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:27648:12147"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..263
                     /note="immunoglobulin light chain variable region"
     V_region        4..263
     V_segment       4..225
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <188..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71844.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       227..263
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           67 a           91 c           83 g           60 t
ORIGIN      
        1 acatggggga gacaacattg gaagtcaaag tgtgcactgg taccagcaca agccaccgca
       61 ggcccctgta ctggtcatct tttattatac cgaacggccc tcaggaatcc ctgagcgatt
      121 ctctggctcc aaatcaggga acaccgccac cctgaccatc agcggggtcg aggccgggga
      181 tgaggctgac tattactgtc aggtgtggga cacaactatt gatcacggct tattcggagg
      241 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01006107             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:26260:8800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006107
VERSION     KCWK01006107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:26260:8800"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71845.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       390..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           88 a          138 c          137 g           98 t
ORIGIN      
        1 atgggggggc ctcaggaggc agcattgacg gtgcctcagc catggcctgg acttttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcaggcac
      121 cctcgatttc agtgtccccc ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaagtgaagt tgtgaactgg taccagcaga agccaccgca ggcccctgtg ttggtcatgt
      241 atgctgatag cgagcggccc tcagggatcc ctgagcgatt ctctggctcc aaatcaggga
      301 acacggccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga catgaatagt catcatctat tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01006108             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:15216:11844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006108
VERSION     KCWK01006108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15216:11844"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..400
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71846.1"
                     /translation="DYYCSSWESSLNWIF"
     J_segment       402..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           89 a          152 c          128 g          108 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg ttaccatctc ctgcactggg
      181 agcagctcca acatcggggc gggtttttat gtgtcctggt accaacagtt ccctggaaca
      241 gcccccaaac tcctcatcta tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggttc ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgctc atcatgggaa agcagcctga attggatatt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01006109             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:11087:10684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006109
VERSION     KCWK01006109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:11087:10684"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..289
                     /note="immunoglobulin light chain variable region"
     V_region        8..289
     V_segment       8..252
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <214..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71847.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       254..289
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           67 a          104 c           82 g           74 t
ORIGIN      
        1 acatgggggg tcaccatctc ctgcactggg agcagctcca acattggagg ttattatata
       61 tcctggtacc agcagctccc aggaacggcc cccaaactcc tcgtctatga caataataag
      121 cgaccctcag gggtttctga ccgattctct ggctccaagt ctggttcctc agccaccctg
      181 accatcactg ggctccagac tgaggatgag gctgattatt actgccagtc ctatgacagc
      241 agtctgagtg ctcgggtatt cggcggaggg acccggctaa ccgtcctagg tcagcccaag
      301 gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01006110             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:23181:14790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006110
VERSION     KCWK01006110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23181:14790"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..404
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71848.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       413..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           93 a          157 c          123 g          108 t
ORIGIN      
        1 acatgggggt ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct ctccttctca ctctgctggt tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag catctggggc ccccggacag agggtcacca tctcctgcat
      181 tagcagcagc tccaacatcg gggcggctta ttatgtatcc tggtaccaac agttcccagg
      241 aacagccccc aaactcctca tccatgaaaa taataagcga ccctcagggg tttctgaccg
      301 attctctggc tccaagtctg gtccctcagc ctccctgacc atcactggac tccaatctga
      361 ggatgaggct gattattact gtttagcatg ggataccagc ctgaattgga tcttcggcgg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01006111             380 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:8073:2344
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006111
VERSION     KCWK01006111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 380)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:8073:2344"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    12..342
                     /note="immunoglobulin light chain variable region"
     V_region        12..342
     V_segment       12..307
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <270..>314
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71849.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       309..342
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        343..>380
                     /gene="IGLC"
BASE COUNT           72 a          116 c           99 g           93 t
ORIGIN      
        1 actggggggt tcaggctgcc ccgactcagc ctccctctgt gtccgggtct cctggacagt
       61 cggtcaccat ctcctgcact ggaaccagca gtgatgttgg gtattataac gctgtgtctt
      121 ggtaccaaca gcatccaggc aaagccccca aactcatgat ttatgacgtc attaagcggc
      181 cctcaggggt ttctgatcgc ttctctggct ccaagtctgg cgacacggcc tccctgacca
      241 tctctgggct ccaggctgag gatgaggctg attattactg cagctcatat gcaggcagaa
      301 ataatttttt attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      361 cctcggtcac tctcttcccg
//
LOCUS       KCWK01006112             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:20986:3014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006112
VERSION     KCWK01006112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20986:3014"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71850.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          154 c          129 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccag cagtttccag
      241 gaacggcccc caaactcctc atctatgaaa atgataaacg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct gattcctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cttgagtgtg gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01006113             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:21374:12094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006113
VERSION     KCWK01006113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21374:12094"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..254
                     /note="immunoglobulin light chain variable region"
     V_region        112..254
     V_segment       112..217
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <185..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71851.1"
                     /translation="DYYCQTWDIGIWVF"
     J_segment       218..254
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           48 a          103 c           72 g           69 t
ORIGIN      
        1 acatggggag agccctgagg agtctgcacc atggcctgga ccccaatcct cctcctcctc
       61 actctcctcc ttcactgcac agggtctctc tcccagcctg tgctgactca gtcgcttctc
      121 aggctccagc tccggggctg agcgctacct caccatctcc aacctccagt ctgaggatga
      181 ggctgattat tactgtcaga cctgggatat tggcatttgg gtattcggcg gagggacccg
      241 gctaatcgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01006114             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:14134:5778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006114
VERSION     KCWK01006114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14134:5778"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71852.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          160 c          112 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcacttcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006115             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:19485:20923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006115
VERSION     KCWK01006115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19485:20923"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71853.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          160 c          112 g          115 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagtcagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggttctta caccatattc tggtaccagc agaagccagg gagtcctccc cggttccttc
      241 tgtactacta ctcagactca aataatcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaata tgcttcagcc aatgcagggc ttttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatgtggc acagcagcgc ttatgcctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006116             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:6069:14803
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006116
VERSION     KCWK01006116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6069:14803"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..431
                     /note="immunoglobulin light chain variable region"
     V_region        110..431
     V_segment       110..395
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71854.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       399..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           94 a          146 c          133 g           96 t
ORIGIN      
        1 acatgggggc cctgtctggg tctcaggagg cagcattgac ggtgcctcag ccatggcctg
       61 gacccttctc ctcctcggcc tcctcgctta ctgcacaggc tctgcgacct cctatgaatt
      121 gactcagtca ccctcagtgt cagcggcctc aggacagccg gccaggatca cctgtggggg
      181 agacaacatt ggaactaaaa ctgtgcactg gtaccaacag aagccaccgc agggccctgt
      241 attggtcatc tttgctgata gtagacgacc ctcagggatc cctgagcgat tctctggctc
      301 caactcaggg aacaccgcca ccctgaccat cagcagggtc gaggccgggg atgaggctga
      361 ctattactgt caggtgtggg acagtagtag taaatggata ttcggcgggg ggacccggct
      421 aaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006117             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:18740:14388
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006117
VERSION     KCWK01006117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18740:14388"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71855.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           92 a          160 c          111 g          110 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgcttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggt gctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01006118             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:19594:15572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006118
VERSION     KCWK01006118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19594:15572"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71856.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          150 c          115 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcagactcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01006119             277 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:5009:5385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006119
VERSION     KCWK01006119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 277)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5009:5385"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..239
                     /note="immunoglobulin light chain variable region"
     V_region        3..239
     V_segment       3..202
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <164..>211
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71857.1"
                     /translation="DYYCAAWDDSLSSYIF"
     J_segment       203..239
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        240..>277
                     /gene="IGLC"
BASE COUNT           54 a           90 c           70 g           63 t
ORIGIN      
        1 acatggggtg tcctggtacc agcacctccc aggaacagct cccaaactcc tcatctatta
       61 taatgatcaa cgaggctcag gtgtctctga ccgattctct ggctccaagt ctggcacgtc
      121 agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt actgcgcagc
      181 gtgggatgat agcctgagca gttacatctt cgctgctggg acccggctca ccgtcctagg
      241 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01006120             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:14975:16966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006120
VERSION     KCWK01006120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14975:16966"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71858.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       414..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          167 c          117 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtcttgg tggtaaaaac atttactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgcg
      301 tctctggctc caaggacacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gttttattcg
      421 gaggagggac ccgtctgacc gccctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01006121             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:26730:11462
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006121
VERSION     KCWK01006121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:26730:11462"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..251
                     /note="immunoglobulin light chain variable region"
     V_region        1..251
     V_segment       1..214
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71859.1"
                     /translation="DYYCAVWDDSLSGYIF"
     J_segment       215..251
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           56 a           91 c           73 g           69 t
ORIGIN      
        1 caacatcgga agtcatagtg tctcctggta ccagcagctc ccaggaacag ctcccaaact
       61 cctcatctat tatagtgatc aacgagcctc aggtgtctct gaccgattct ctggctctca
      121 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      181 ttattgcgca gtatgggatg atagcctgag cggttacatc ttcggtgctg ggacccggct
      241 cgccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01006122             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:6005:19731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006122
VERSION     KCWK01006122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6005:19731"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71860.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           89 a          155 c          127 g          110 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgagtcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc aggccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagtctg agcggataca tcttcggtgc
      421 tgggacccgg ctcgccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01006123             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:20828:5160
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006123
VERSION     KCWK01006123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20828:5160"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71861.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           96 a          162 c          112 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcaac tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctgccta ccacatacac tggtaccaac agaagccagg gagtcccccc cggtatcttc
      241 tgagttacag atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaaa tgcttcaacg aacacaggca ttttacacat ctctgggctc cagtctgagg
      361 atgaggctga ctatttctgt gccattggac acagcagcgg tccttacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01006124             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:27918:18617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006124
VERSION     KCWK01006124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:27918:18617"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71862.1"
                     /translation="DYYCSSYADSNIFFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          152 c          118 g          112 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccaa catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgcagctcat atgcagacag taatattttc ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01006125             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:10360:3142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006125
VERSION     KCWK01006125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10360:3142"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..424
                     /note="immunoglobulin light chain variable region"
     V_region        101..424
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71863.1"
                     /translation="DINCHSADSSANHWVF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>463
                     /gene="IGLC"
BASE COUNT          102 a          133 c          125 g          103 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgttctg gagaaatact
      181 ggcaaaaaaa tatggtcagt ggttccagca gaagccaggc caggcccctg ttgtggtgat
      241 atataaggac agtgagaggc cctcagggat ccctgagcga ttctctaggt ccatttcagg
      301 gacaacaatt accttgacca tctgtggggc cccggcagaa gatgaggctg acattaactg
      361 tcattcagca gacagcagtg ctaatcattg ggtcttcggc ggagggaccc ggctaaccgt
      421 cctatgtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006126             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:14505:12824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006126
VERSION     KCWK01006126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14505:12824"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..397
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71864.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       402..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           90 a          154 c          117 g          109 t
ORIGIN      
        1 acatggggga tctcaggagg cagcgctctc aggacttctc caccatggtc tgggctctgc
       61 tcctcctcac cctcctcact cagggcacag gatcctgggc tcaggctgcc ccgactcaga
      121 ctccctctgt gtccgggtct cctggacagt cggtcaccat ctcctgcact ggaaccagca
      181 gtgatattgg gtattatcat gctgtgtctt ggtaccaaca tcatccaggc aaagccccca
      241 aactcatgat ttatgaggtc aataaacggc ccgcaggggt ctctgatcgc ttctctggct
      301 ccaagtctgg caacacggcc tccctgacca tctctgggct ccagactgag gatgaggctg
      361 attattactg cagctcatat gcaggcagca acactttatt cttcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01006127             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:6955:6067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006127
VERSION     KCWK01006127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:6955:6067"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..380
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71865.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       393..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           85 a          149 c          134 g           93 t
ORIGIN      
        1 acatgggggt ctcaggaggc agcattgacg gtgcctcagc catggcctgg acccttctcc
       61 tcctcggcct cctcgctcac tgcacaggct ctgcggcctc ctatgagctg actcagccac
      121 cctcggtgtc agcggcctca ggacagacgg ccaggatccc ctgtggggga gacaacattg
      181 gaactaaata tgtgcactgg taccagcaga agccagcgca ggcccctgtg ttggtcatct
      241 atgctgatac cagacggccc tcagggatcc ctgagcgatt ctctggctcc aactcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccggata tgaggctgac tatttctgtc
      361 aggtgtggga cgatagtagt gatcatccgg ttttcggcgg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01006128             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:14739:16691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006128
VERSION     KCWK01006128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14739:16691"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71866.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          144 c          133 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtcaa ctggtaccaa cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgacc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgcggccg tggatgaggc tgactattac
      361 tgtcaggttt gggacattta tactgatcat ccggtgttgt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01006129             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:4159:11975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006129
VERSION     KCWK01006129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4159:11975"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..391
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71867.1"
                     /translation="DYYCLAWDTSLNWIF"
     J_segment       400..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           92 a          151 c          120 g          105 t
ORIGIN      
        1 acatgggggt gggcacagga ggcagcactc aggacagtct ccagcatggc ctggtctctc
       61 cttctcactc tgctggttca ctgcacaggg tcctgggccc agtctgtgct gacgcagccg
      121 ccctcagcat ctggggcccc cggacagagg gtcaccatct cctgcattag cagcagctcc
      181 aacatcgggg cggcttatta tgtatcctgg taccaacagt taccaggaac agcccccaaa
      241 ctcctcatct ttgaaaataa taagcgaccc tcaggggttt ctgaccgatt ctctggctcc
      301 aagtctggtc cctcagcctc cctgaccatc actggactcc aatctgagga tgaggctgat
      361 tattactgtt tagcatggga taccagcctg aattggatct tcggcggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01006130             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:10622:7731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006130
VERSION     KCWK01006130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10622:7731"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71868.1"
                     /translation="DYYCQSVDSSAHHPLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          101 a          136 c          123 g          103 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctggggcc tcctatgagg tgacacagtc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagcaatact
      181 ggcaaataat tatgctcagt ggttccagca gaagccagac caggcccctg tgttggtgat
      241 atataaagac actgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacaatt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagtt gacagcagtg cccatcatcc gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006131             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:25731:4940
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006131
VERSION     KCWK01006131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:25731:4940"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..400
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71869.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       401..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           92 a          161 c          110 g          112 t
ORIGIN      
        1 acatggggca gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccca gcctgtgctg acccagccaa cctccctctc
      121 agcatctccg ggagcatcag ccagactcag ctgcaccttg agcagtggca tcaatgttgg
      181 tagttacagc atattctggt accagcagaa gccagggagt cctccccggt accttctgta
      241 ctactactca gactcaagta aacaccaggg ctctggagtc cccagccgct tctctggatc
      301 caaagatgct tcggccaatg caggcctttt actgatctct gggctccagt ctgaagatga
      361 ggctgactat tactgtgcca tatggcacag cagcgcttct tacttcttcg gtactgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01006132             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:13021:7770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006132
VERSION     KCWK01006132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13021:7770"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71870.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       373..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           96 a          141 c          114 g           95 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga agaattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtcca gatcatctat gaggacagta
      241 aacggccctc tgggatccct gagagaagct ctggctccag ctcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aagctgacta ctactgtttc tcaacagaca
      361 ccagtggtaa tcgggtattc ggcggaggga cccgtctaac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01006133             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:25510:14101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006133
VERSION     KCWK01006133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:25510:14101"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71871.1"
                     /translation="DYYCYSADSSGYGLF"
     J_segment       386..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>460
                     /gene="IGLC"
BASE COUNT           92 a          142 c          126 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaagatc acctgctctg gagatgcact
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcgt
      241 cgatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgatgctg actactactg
      361 ttactcagca gacagcagtg gttatggctt attcggagga gggacccggc tgaccgtcct
      421 acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01006134             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:12810:8036
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006134
VERSION     KCWK01006134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12810:8036"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71872.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          156 c          118 g          113 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggagc atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgctggct accacataca ctggtatcag cagaagccag ggagtccccc ccggtatctt
      241 ctgaggtaca aatcagactc agataagggc ctgggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc gaatacaggg attttacaca tctctggttt ccagtctgag
      361 gatgaggctg actattactg tgccattggc cacggcagcg gtgattacat cttcggtact
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01006135             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:19593:9691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006135
VERSION     KCWK01006135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19593:9691"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..395
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71873.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       397..432
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           94 a          150 c          117 g          109 t
ORIGIN      
        1 acatgggggt ggagccaggg atcccttcca atatcagcac catggcctgg actctgctcc
       61 tcctccagtt cctcctcact tgctgcccag ggtccaattc tcaggctgta gtgactcagg
      121 agccctcaat gactgtgtcc ccaggaggga cagtcactct cacctgtgct tccagcactg
      181 gagcagtcac cagtggtcac tctccacact ggttccagca gaaacctgga caagccccca
      241 agacactgat ttataataca aactacagac actcctggac tcctgcccgg ttctcaggct
      301 ccctccttgg gggtaaagct gccctgacac tgtcaggtgc gcagcctgag gatgaggctg
      361 agtattattg tttactgtac tatagtggtg ctcagctgtt attcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01006136             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:20145:5336
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006136
VERSION     KCWK01006136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20145:5336"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71874.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          148 c          129 g           97 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactacaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtc aaagtgtgca ctggtaccag cacaagccac cgcaggcccc tgttctggtc
      241 atcttttatt ataccgaacg gccctcagga atccctgagc gaatctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacacaag tcttgatcac ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006137             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:7147:15220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006137
VERSION     KCWK01006137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:7147:15220"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71875.1"
                     /translation="DYYCQVWDSSSDHVFF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          148 c          134 g           94 t
ORIGIN      
        1 acatggggct gggcctcagg aagcagcctt ggcggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca gactctgcgg cctcctatga tatgactcag
      121 ccacgctcag tgtctgtgtc cccaggacag acggccagga tcacctgtgg gggagacgac
      181 actagaagta aaaatgtgat ttggtaccag cagaagccac cgcaggcccc cgcgctggtc
      241 atctattatg atagcgaccg gccctcaggg atccctcagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtgatcat gtgtttttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006138             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:15572:10415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006138
VERSION     KCWK01006138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15572:10415"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71876.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       414..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           89 a          157 c          127 g          115 t
ORIGIN      
        1 acatgggggc tctgcttcac cggtgttggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtctccatct
      181 cctgcactgg gagcagctcc aacattggag atttttatgt gcagtggtac cagcaccttc
      241 caggaacggc ccccaaactc ctcatctatg aaaataataa gcgaccctca ggggtttctg
      301 atcgattctc tggctcccag tctggaacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagtttgatt gctgtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01006139             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:10284:20930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006139
VERSION     KCWK01006139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10284:20930"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..374
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71877.1"
                     /translation="DYSCQVWDSETDYYIF"
     J_segment       386..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           90 a          146 c          129 g           96 t
ORIGIN      
        1 acatgggggt ctcaggaggc agcattgacg gtgcctcagc catggcctgg acccttctcc
       61 tcctcggcct cctcgctcac tgcacaggct ctgcgacctc ctttgagctg actcagccac
      121 cctcggtgtc agcggcctca ggacagacgg ccaggatcac ctgtggggga gacaacattg
      181 gaattaaatt tgtccactgg taccagcaga agccagcgca ggcccctgtg aaggtcatct
      241 atgctgatga caaacggccc tcagggatcc ctgagagatt ctctggctcc aattcaggga
      301 acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattcctgtc
      361 aggtgtggga cagtgagact gattattaca tcttcggttc tgggacccgg ctcaccgtcc
      421 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01006140             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:19176:13759
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006140
VERSION     KCWK01006140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19176:13759"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..449
                     /note="immunoglobulin light chain variable region"
     V_region        116..449
     V_segment       116..412
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71878.1"
                     /translation="DYYCQTWDTDIVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           91 a          164 c          127 g          105 t
ORIGIN      
        1 acatgggggc agtgtggctg cctcagcaga gccctgagga gtctgcacca tggcctggac
       61 cccaatcctc ctcctcctcc tcactctcct ccttcactgc acagggtctc tctcccagcc
      121 tgtgctgact cagtcgccct ctgtctctgc ctccctggga gcctcggtca aactcacctg
      181 tactttgaac agtgggcaca gcagctacac catcgcatgg catcagcagc agcaagggaa
      241 ggccccccgg tacttgatgt ggcttaaaag tgaaggcagc catagcaagg gggacgggat
      301 ccctgatcgc ttctcaggct ccagctccgg ggctgagcgc tacctcacca tctccaacct
      361 ccagtctgag gatgaggctg attattactg tcagacctgg gatactgaca ttgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCWK01006141             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:27042:10985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006141
VERSION     KCWK01006141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:27042:10985"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71879.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       402..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          150 c          121 g          114 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggttcaggct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgatgt tgggtattat aacgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 ccaaactcat gatttatgac gtcattaagc ggccctcaga ggtttctgat cgcttctctg
      301 gctccaagtc tggcgacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca gaaataattt tttattcgga ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006142             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:12676:14786
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006142
VERSION     KCWK01006142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12676:14786"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71880.1"
                     /translation="DYFCQLFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          163 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagc tatttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006143             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:11292:12147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006143
VERSION     KCWK01006143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11292:12147"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71881.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       392..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          139 c          139 g           99 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 acaccctcga tttcagtgtc cccaggacag acggccagga tcacctgtgg gggaggcaac
      181 attggaggtg aagttgtgaa ctggtaccag cagaagccac cgcaggcccc tgtgttggtc
      241 atgtatgctg atagcgagcg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacatgaa tagtcatcat ctgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006144             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:12427:6240
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006144
VERSION     KCWK01006144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12427:6240"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71882.1"
                     /translation="DYYCQVWDMRSDQPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          142 c          143 g           91 t
ORIGIN      
        1 acatgggggg gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgcgg gggagacaag
      181 attggaagtg aagttgtgaa ctggtaccag aagaagccag cgcaggcccc tgcactggtc
      241 atctatgctg atagcgaacg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcaggggg gtcgaggccg ggggtgaggc tgactattac
      361 tgtcaggtgt gggacatgcg tagtgatcaa ccgctattcg gcggagggac ccggctaacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006145             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:18555:8954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006145
VERSION     KCWK01006145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:18555:8954"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71883.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       414..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           91 a          154 c          130 g          113 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag gttattatgt gcagtggtac cagcagtttc
      241 caggaacggc ccccaaactc ctcatctatg aaaatgataa acgaccctca ggggtttctg
      301 atcgattctc tggctcccag tctgattcct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagcttgagt gtggtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01006146             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:17978:14555
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006146
VERSION     KCWK01006146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17978:14555"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..259
                     /note="immunoglobulin light chain variable region"
     V_region        1..259
     V_segment       1..224
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>234
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71884.1"
                     /translation="DYYCQVWDSDSKWVF"
     J_segment       226..259
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        260..>300
                     /gene="IGLC"
BASE COUNT           65 a           88 c           90 g           57 t
ORIGIN      
        1 acatggggcg gggacagcct tggaacaaaa tatgtgcact ggtaccagca gaagccaacg
       61 caggcccctg tggtggtcat ctatgctgat aataaacggc cctcagggat ccctgagcga
      121 ttctctggct ccaactcagg gaacaccgcc accctgacca tcagcagggt cgaggccggg
      181 gatgaggctg actattactg tcaggtgtgg gacagtgata gtaagtgggt cttcggcgga
      241 gggacccggc taaccgtccc aggtcagccc aagtctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01006147             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:6743:11340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006147
VERSION     KCWK01006147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:6743:11340"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..282
                     /note="immunoglobulin light chain variable region"
     V_region        8..282
     V_segment       8..245
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71885.1"
                     /translation="DYYCQVWDSSTRYAVF"
     J_segment       252..282
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>320
                     /gene="IGLC"
BASE COUNT           65 a           92 c           99 g           64 t
ORIGIN      
        1 acatgggggc caggatcgcc tgtgggggag acagcattgg aagtgaaaat gtgttctggt
       61 accagcagaa gccacggcag gcccctgtcc tggtcatcta tggtgatacg aaacggccct
      121 cagggatccc tgagcgattc tctggctcca tctctgggaa caccgccacc ctgaccatca
      181 acagggtcga ggccggggat gaggctgact attactgtca ggtgtgggac agtagtacta
      241 gatacgcggt tttcggcgga gggacccggc taaccgtcct aggtcagccc aaggctgccc
      301 cctcggtcac tctcttcccg
//
LOCUS       KCWK01006148             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:21487:14550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006148
VERSION     KCWK01006148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21487:14550"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..258
                     /note="immunoglobulin light chain variable region"
     V_region        8..258
     V_segment       8..221
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <183..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71886.1"
                     /translation="DYYCQVWDMNSHHLLF"
     J_segment       223..258
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           62 a           83 c           90 g           61 t
ORIGIN      
        1 acatgggcaa cattggaagt gaagttgtga actggtacca gcagaagcca ccgcaggccc
       61 ctgtgttggt catgtatgct gatagcgagc ggccctcagg gatccctgag cgattctctg
      121 gctccaaatc agggaacacg gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg
      181 ctgactatta ctgtcaggtg tgggacatga atagtcatca tctgttattc ggaggaggga
      241 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01006149             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:11036:17376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006149
VERSION     KCWK01006149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11036:17376"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71887.1"
                     /translation="DYYCSSYAGRNNILF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          151 c          120 g          112 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gttcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt ggatattata acgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 caaactcata atttttgacg tcattaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcgacacgg cctccctgac catctctggg ctccgggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcag aaataatatt ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01006150             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:19120:13424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006150
VERSION     KCWK01006150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19120:13424"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71888.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          162 c          109 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt tagcagtggc ttcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01006151             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:22974:6957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006151
VERSION     KCWK01006151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22974:6957"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71889.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       408..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          150 c          127 g          116 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcag tatttcttgc
      181 actgggagca gctccaacat tggaggttat tatgtgcagt ggtaccagca gcttccagga
      241 acggccccca aactcctcat ctatgaaaat gataaacgac cctcagggat ttctgatcga
      301 ttctctggct cccagtctga ttcctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagcagct tgagtgttgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01006152             273 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:26139:5640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006152
VERSION     KCWK01006152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 273)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 273)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:26139:5640"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..235
                     /note="immunoglobulin light chain variable region"
     V_region        113..235
     V_segment       113..196
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <160..>207
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71890.1"
                     /translation="DFYCQVWDIRSDRPLF"
     J_segment       203..235
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        236..>273
                     /gene="IGLC"
BASE COUNT           39 a           91 c           81 g           62 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gctatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggcc tcccatgatc tgactcggcc
      121 accctgacca tccgcggggt cgaggccggg gatgaggctg acttttactg tcaggtgtgg
      181 gacattcgta gtgatcgtcc gctattcggc ggagggaccc ggctcaccgt cctaggtcag
      241 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006153             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:7041:10824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006153
VERSION     KCWK01006153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7041:10824"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71891.1"
                     /translation="DYYCQLWDSSVDHGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          140 c          136 g          100 t
ORIGIN      
        1 acatgggggc tgggcctcag gaggcagcat tgacggtgcc tcagccatgg cctggacttt
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gcctcctatg atctgactca
      121 gccagcctcg gtgtcagtgt ccccgggaca gacggccagg atcacctgtg ggggagacaa
      181 tattggaagt aaaaatgtgc actggtacca gcaggagcca ccgcaggccc ctgtgttggt
      241 catcttttat gataacaaac ggccctcagg gatccctgag cgattctctg gctccaaatc
      301 agggaacatc gccaccctga ccatcagcga ggccgaggcc ggggatgagg ctgactatta
      361 ctgtcagctg tgggacagta gtgttgatca tggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01006154             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:5343:8818
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006154
VERSION     KCWK01006154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5343:8818"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71892.1"
                     /translation="DYYCAVWDNSLTSPLF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          152 c          115 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg ggactcccgg gcagagtgtc accatctctt gctctggaag caactccaac
      181 attggaaata attatgtata ctggtaccag cacctcccag gaacggcccc caaggtcctc
      241 atctattata gttatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgaactg aggatgaggc tgattattac
      361 tgtgcagtat gggataacag cctgaccagt ccgttgttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006155             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:24179:9585
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006155
VERSION     KCWK01006155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24179:9585"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..445
                     /note="immunoglobulin light chain variable region"
     V_region        97..445
     V_segment       97..405
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71893.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          161 c          117 g          109 t
ORIGIN      
        1 acatggggcc ccactgtggg gaaagaggct gtgtccacca tggcctggac tcctctcctc
       61 ctcctgctcc tctctcactg cacaggttcc ctctccaagc ctatgctgac tcagccggcc
      121 tccctctcag catctcctgg aacatcagcc agtctcacat gcaccttcag cggtggcatc
      181 aatgttgctg gctaccacat acactggtac cagcagaagc cagggagtcc tccccgatat
      241 cttctgagat acaaatcgga ctcagataag ggccagggct ctggagtccc cagccgcttc
      301 tctggatcca aagatgcttc agcgaacaca gggattttac gcatctctgg gctccagtct
      361 gaggatgagg ctgactatta ctgtgccatt ggacacagca gcggtgatta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01006156             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:25124:12337
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006156
VERSION     KCWK01006156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:25124:12337"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..343
                     /note="immunoglobulin light chain variable region"
     V_region        13..343
     V_segment       13..306
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <268..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71894.1"
                     /translation="DYYCQSYDSSLIAVLF"
     J_segment       307..343
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        344..>381
                     /gene="IGLC"
BASE COUNT           75 a          118 c           99 g           89 t
ORIGIN      
        1 acatgggggg cccagtctgt gctgacgcag ccgccctcag tgtctggggc gcccgggcag
       61 agggtcacca tctcctgcac tgggagcatc tccaacattg gagattattt tgtgcagtgg
      121 taccagcacc ttccaggaac ggcccccaaa ctcctcatct atgaaaataa taagcgaccc
      181 tcagggattt ctgatcgatt ctctggctcc cagtctggaa cctcagcctc cctgaccatc
      241 actggactcc agtctgagga tgaggctgat tattactgcc agtcctatga cagcagtttg
      301 attgctgtgt tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      361 ccctcggtca ctctcttccc g
//
LOCUS       KCWK01006157             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:4175:13015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006157
VERSION     KCWK01006157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:4175:13015"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..254
                     /note="immunoglobulin light chain variable region"
     V_region        8..254
     V_segment       8..217
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <179..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71895.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       218..254
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           61 a           89 c           80 g           62 t
ORIGIN      
        1 acatgggatt ggaagtaaga gtgtgcactg gtaccagcac aagccaccgc aggcccctat
       61 cctggtcatc tattattata ccgaacgacc ctcggcgatc cctgagcgat tctctggctc
      121 caaatcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga
      181 ctattactgt caggtgtggg acactactat tgatcatggc tttttcggag gagggacccg
      241 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01006158             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:14723:14136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006158
VERSION     KCWK01006158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:14723:14136"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..432
                     /note="immunoglobulin light chain variable region"
     V_region        99..432
     V_segment       99..395
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71896.1"
                     /translation="DYYCQTWDTGIVSF"
     J_segment       396..432
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           86 a          159 c          122 g          103 t
ORIGIN      
        1 acatgggggc agagccctga ggagtctgca ccatggcctg gaccccaatc ctcctcctcc
       61 tcctcactct cctccttcac tgcacagggt ctctctccca gcctgtgctg actcagtcgc
      121 cctctgcctc tgcctccctg ggagcctcgg tcaagctcac ctgtactctg agcagtggac
      181 acagcagcta caccatcgca tggcatcagc accagcaagg gaaggcccct cggtatttga
      241 tgtggcttaa aagtgatggc agccacagca agggggacgg gatccctgat cgcttctcag
      301 gctccagttc cggggctgag cgctacctca ccatctccaa tttccagtct gaggatgagg
      361 ctgattatta ctgtcagacc tgggatactg gcattgtgtc attcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01006159             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:4445:16615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006159
VERSION     KCWK01006159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:4445:16615"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..384
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71897.1"
                     /translation="DYYCQVWDSTSDHYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          152 c          133 g           94 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccaggg tcacctgtgg gggagacaac
      181 attggaacta cgtttgtgca ctggtaccag cagaatccgc cgcaggcccc tgtgcaggtc
      241 ctctttgcgg ataacaaacg gccctcaggg atccctgaac gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtac tagtgatcat tacatcttcg gtggtgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01006160             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:15230:7911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006160
VERSION     KCWK01006160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15230:7911"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71898.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       411..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          157 c          129 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtttcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat cttttataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgatagcc tgagcggtcc ggtattcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01006161             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:24212:6687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006161
VERSION     KCWK01006161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24212:6687"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71899.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       373..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           96 a          140 c          112 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga agaattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtcca gatcatctat gaggacagta
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaagatg aagttgacta ctactgcttc tcaacagaca
      361 ccagtggtaa tcgggtattc ggcggaggga cccgtctaat cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01006162             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:22689:5595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006162
VERSION     KCWK01006162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22689:5595"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71900.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       403..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           91 a          158 c          113 g          113 t
ORIGIN      
        1 acatggggga gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccca gcctgtgctg acccagccaa cctccctctc
      121 agcatctccg ggagcatcag tcagactcag ctgcaccttg agcagtggca tcaatgttgg
      181 ttcttacacc atattctggt accagcagaa gccagggagt cctccccggt tccttctgta
      241 ctactactca gactcaaata atcaccaggg ctctggagtc cccagccgct tctctggatc
      301 caaagatgct tcagccaatg cagggctttt actgatctct gggctccagt ctgaagatga
      361 ggctgactat tactgtgcca tgtggcacag cagcgcttat gccttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006163             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:20563:15808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006163
VERSION     KCWK01006163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20563:15808"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71901.1"
                     /translation="DYYCQVWDLNSHHLLF"
     J_segment       391..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          142 c          135 g           99 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccagggtc acctgtgggg gagacaacat
      181 cggaggtgaa gttgtgaatt ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacgcggcc accctgacca tcagcggggt cgaggccgaa gatgaggctg actattactg
      361 tcaggtgtgg gaccttaata gtcatcatct cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006164             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:15318:15054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006164
VERSION     KCWK01006164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15318:15054"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71902.1"
                     /translation="DYYCSSYEGTNSFIF"
     J_segment       401..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          158 c          121 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcaggacgtc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggaccctgg gctcaggctg ccctgactca
      121 gcctccctct gtgtctgggt ctcccggaca gtcggtcacc atctcctgca cgggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccag cagcacccag gcaaagcccc
      241 caaactcatg atttatgatg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaaatct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgaaggcac caacagtttc atcttcggtg ttgggacccg
      421 gctcaccgta ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01006165             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:14257:8661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006165
VERSION     KCWK01006165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14257:8661"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71903.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          159 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgttg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg aaataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacga tagtgctgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006166             295 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:12578:5783
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006166
VERSION     KCWK01006166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 295)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12578:5783"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..257
                     /note="immunoglobulin light chain variable region"
     V_region        8..257
     V_segment       8..223
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>229
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71904.1"
                     /translation="DYYCQSYDSSSVF"
     J_segment       225..257
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>295
                     /gene="IGLC"
BASE COUNT           60 a           95 c           75 g           65 t
ORIGIN      
        1 acatgggggc agcattgaca acggctttgt gtactggtac cagcagcggc cgggcagcgc
       61 tcccaccact gtgatttaca aagataacca aagaccctct ggggtccctg atcggttctc
      121 tggctccatc gacagctcct ccaactctgc ctccctcacc atctctggac tgaaatctga
      181 ggacgaggct gactattact gtcagtctta tgacagcagc agtgtattcg gaggagggac
      241 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006167             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:11095:11827
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006167
VERSION     KCWK01006167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11095:11827"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71905.1"
                     /translation="DYHCQVYDGSAVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          160 c          124 g          112 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagtagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actacttctc cgactcagac aagcagttgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tactcatctc tgggctccag
      361 cctgaggacg aggccgatta tcactgtcag gtgtatgacg gtagtgctgt tttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01006168             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:13701:4898
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006168
VERSION     KCWK01006168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13701:4898"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71906.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          162 c          119 g          111 t
ORIGIN      
        1 acatggggtg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtaataaaaa catgtactgg taccaacaga agccagggag cgctcccagg
      241 ttattcctat actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaactaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtttgaca gtagtgctgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01006169             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:15995:19152
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006169
VERSION     KCWK01006169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15995:19152"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71907.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           90 a          159 c          118 g          107 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagc cagactcaac tgcaccttga gcagtggcgt caatgtgggt
      181 agttacagca tattctggta ccagcagaag ccagggagtc ctccccggta ccttctgtac
      241 taccagtcag actcaaggaa gcaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagccaatgc agggctgtta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccct atggcacagc agcgcttctt gcatcttcgg tggtgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01006170             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1110:23626:10470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006170
VERSION     KCWK01006170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23626:10470"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..426
                     /note="immunoglobulin light chain variable region"
     V_region        97..426
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71908.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       395..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>465
                     /gene="IGLC"
BASE COUNT           93 a          155 c          114 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctcgt gctctggaag cagctccaac
      181 attggaacta attatgtata ctggtaccaa cacctcccag gaacggcccc caaactcctc
      241 atctattata gtaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggataacag cctgaccagt ccggtattcg gaggagggac ccggctgacc
      421 gtcctaagtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006171             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:18665:13064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006171
VERSION     KCWK01006171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18665:13064"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71909.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           88 a          157 c          128 g          111 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aagagtgtct ccatctcctg
      181 ttctggaagc agctccaaca tcggaagtca tagtgtctcc tggtaccagc agctcccagg
      241 aacagctccc aaactcctca tctattatag tgatcaacga gcctcaggtg tctctgaccg
      301 attctctggc tctcagtctg gcacgtcagc ctccctggcc atcagtgggc tccaggccga
      361 ggatgaggct gattattact gcgcagcatg ggatgatagt ctgagcggtt acatcttcgg
      421 tgctgggacc cggctcgccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01006172             325 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:24058:9934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006172
VERSION     KCWK01006172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 325)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:24058:9934"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..287
                     /note="immunoglobulin light chain variable region"
     V_region        8..287
     V_segment       8..251
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>259
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71910.1"
                     /translation="DYYCQVWDSDSKWIF"
     J_segment       255..287
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        288..>325
                     /gene="IGLC"
BASE COUNT           74 a           92 c           98 g           61 t
ORIGIN      
        1 acatggggga cagacggcca ggatcacctg tgggggagac aacattggaa ctaaaaatgt
       61 gcactggtac cagcagaagc cagcgcaggg ccctgtattg gtcatgtttg ctgataccag
      121 acggccctca gggatccctg accgattctc tggctccaac tcagggaaca ccgccaccct
      181 gaccatcagc agggtcgagg ccggggatga ggctgactat tactgtcagg tgtgggacag
      241 tgatagtaaa tggatattcg gcggagggac ccggctaacc gtcctaggtc agcccaaggc
      301 tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006173             435 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:19586:9628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006173
VERSION     KCWK01006173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19586:9628"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..397
                     /note="immunoglobulin light chain variable region"
     V_region        79..397
     V_segment       79..365
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <328..>369
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71911.1"
                     /translation="DYYCDSWDNSGTQF"
     J_segment       366..397
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        398..>435
                     /gene="IGLC"
BASE COUNT           85 a          137 c          118 g           95 t
ORIGIN      
        1 acatgggggg gtgtctccac catggcctgg actcctctct ggctcaccct cctcagtctt
       61 tgcacaggtt ctatggtttc ttctgagctg actcaggacc ctgcagtgtc tgtggccttg
      121 gggcagacag tcaggattac ctgccaagga gacagcctca gaagctctta tgcaagctgg
      181 taccaacaga ggccaggcca ggcccctgtg ctggtcgtct atggtaacaa ctaccggccc
      241 tcagggatcc cagagcgatt ctctggctcc tactcccgaa acacagcttc cttgaccatc
      301 actggggctc aggtggaaga tgaggctgac tattactgtg actcctggga caacagcgga
      361 acccaattcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      421 gtcactctct tcccg
//
LOCUS       KCWK01006174             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:19580:9576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006174
VERSION     KCWK01006174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19580:9576"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..436
                     /note="immunoglobulin light chain variable region"
     V_region        90..436
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71912.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           89 a          163 c          110 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt tagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcatct aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaggatgc ttcggccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc ggtactggga
      421 cccggctcac cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01006175             284 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:19940:6229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006175
VERSION     KCWK01006175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 284)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19940:6229"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..246
                     /note="immunoglobulin light chain variable region"
     V_region        7..246
     V_segment       7..209
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <174..>218
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71913.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       212..246
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        247..>284
                     /gene="IGLC"
BASE COUNT           58 a           84 c           78 g           64 t
ORIGIN      
        1 acatggggta ccagcagaag ccggggagcg ctcccaggtt attcctgtac tactattccg
       61 actcagacaa gcagctggga cctggggtcc ccaatcgagt ctctggctcc aaggagacct
      121 caagtaacac agcgtttttg ctcatctctg ggctccagcc tgaggacgag gccgattatt
      181 actgtcaggt gtatgacagt agtgctaatg tcttattcgg aggagggacc cggctgaccg
      241 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01006176             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:20987:8548
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006176
VERSION     KCWK01006176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20987:8548"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71914.1"
                     /translation="DYYCAAWDESLRGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          155 c          128 g          103 t
ORIGIN      
        1 atgggggcag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgcgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tgggagcagc tccaacatcg gaagaaatag tgtatcctgg taccagcagc tcccaggaac
      241 agctcccaaa atcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagccgc cctggccatc agcgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgaaagcctg aggggttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01006177             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:6528:20456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006177
VERSION     KCWK01006177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:6528:20456"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..447
                     /note="immunoglobulin light chain variable region"
     V_region        118..447
     V_segment       118..411
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71915.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       416..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>486
                     /gene="IGLC"
BASE COUNT           97 a          161 c          119 g          109 t
ORIGIN      
        1 acatggggag cttcagctgc ggtacagaag gcaggactca ggataatctc cagcatggcc
       61 tggttccctc tcgtcctcac cctcctcact cactgtgcag ttccagggtc ctgggcccag
      121 tctgtgctga ctcagccacc ctcagcgtct gggactcccg ggcagagtgt caccatctcg
      181 tgctctggaa gcagctccaa cattggaact aattatgtat actggtacca acacctccca
      241 ggaacggccc ccaaactcct catctattat agtaatcagc gaccctcagg ggtccctgac
      301 cgattctctg gctctaagtc tggcacctca gcctccctgg ccatcactgg tctccgatct
      361 gaggatgagg ctgattatta ctgtgcagca tgggataaca gcctgaccag tccggtattc
      421 ggaggaggga cccggctgac cgtcctaagt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01006178             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:29500:13349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006178
VERSION     KCWK01006178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:29500:13349"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71916.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           89 a          156 c          125 g          111 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcatct attatagtga tcaacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctct cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagtctg agcggttaca tcttcggcgc
      421 tgggacccgg ctcgccgtcc taggtcagtc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01006179             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:3129:18713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006179
VERSION     KCWK01006179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:3129:18713"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71917.1"
                     /translation="DYYCAAWDDSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           86 a          157 c          128 g          110 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccgggaag agtgtctcca tctcctgttc
      181 tggaagcagc tccaacatcg gaagtcatag tgtctcctgg taccagcagc tcccaggaac
      241 agctcccaaa ctcctcgtct attatagtga tcaacgagcc tctggtgtct ctgaccgatt
      301 ctctggcgct cagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga tgatagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcgccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCWK01006180             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:20389:4738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006180
VERSION     KCWK01006180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20389:4738"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..443
                     /note="immunoglobulin light chain variable region"
     V_region        95..443
     V_segment       95..404
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71918.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       406..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           96 a          158 c          110 g          117 t
ORIGIN      
        1 acatgggccc actgcaggga aagaggctgt gtccaccatg gcctggactc ctctcctcct
       61 cctgctcctc tctcactgca caggttccct ctcgcagcct gtgctgactc agccaacctc
      121 cctctcagct tctcctggag catcagccag actcacctgc accttgaaca gtggcatcag
      181 tgttgctaat tacaggatat tctggtacca ccagaagcca gggagtcctc cccggtatct
      241 tctgaactac cacacagact cagatattca ccagggctct ggagtcccca gccgcttctc
      301 tggatccaaa gatgcttcgg ccaatgcagg gattttactc atctctggac tccagtctga
      361 ggatgaggct gactattact gtatgatttg gcacaacaat gcttattggg ttttcggcgg
      421 agggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCWK01006181             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:17099:4398
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006181
VERSION     KCWK01006181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17099:4398"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71919.1"
                     /translation="DYYCSSYAGSNSLFF"
     J_segment       404..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          151 c          121 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gactccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattatc atgctgtgtc ttggtaccag catcatccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataaacg gcccgcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tgattattac tgtagctcat atgcaggcag caacagttta ttcttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01006182             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:23593:9340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006182
VERSION     KCWK01006182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23593:9340"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..403
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71920.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       405..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           96 a          152 c          116 g          116 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcgcagcctg tgctgactca gccaacctcc
      121 ctctcagcat ctcctggagc atcagccaga ctcacctgca ccttgagcag tggcttcagt
      181 attggtaatt acaggatatt ctggtaccag cagaagccag ggagtcctcc ccggtatctt
      241 ctgagctacc acacagactc agatatgcac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgtttcggc caatgcaggg attttactca tctctggact ccagtctgag
      361 gatgaggctg actattactg tatgatttgg cacaacaatg cttattgggt attcggcgga
      421 gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01006183             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2101:9836:11650
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006183
VERSION     KCWK01006183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:9836:11650"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71921.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          155 c          120 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggaacatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ttggctacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatacaaatc ggactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac gcagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtga ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01006184             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:5854:13310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006184
VERSION     KCWK01006184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:5854:13310"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..250
                     /note="immunoglobulin light chain variable region"
     V_region        7..250
     V_segment       7..212
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <175..>222
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71922.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       214..250
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        251..>288
                     /gene="IGLC"
BASE COUNT           61 a           89 c           79 g           59 t
ORIGIN      
        1 acatggggaa gtcaaagtgt acactggtac cagcacaagc caccgcaggc ccctgttctg
       61 gtcatctttt attataccga acggccctca ggaatccctg agcgattctc tggctccaaa
      121 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      181 tactgtcagg tgtgggacac aactattgat cacggcttgt tcggaggagg gacccggctg
      241 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01006185             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:24162:12460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006185
VERSION     KCWK01006185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24162:12460"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71923.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          156 c          123 g          108 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata atgtgtcctg gtaccagcac ctcccaggaa
      241 cagctcccaa actcctcatc tattataatg atcaacgagg ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcgtggg atgataggct gagcagttac atcttcgctg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01006186             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:8816:11517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006186
VERSION     KCWK01006186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8816:11517"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71924.1"
                     /translation="DYYCYSADSSGHGFF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           87 a          141 c          118 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagccggcc aggatcacct gctctggaga tgtattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtatt ggtcatctct gaggacaccg
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gtagtggtca tggcttcttc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01006187             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:16224:2615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006187
VERSION     KCWK01006187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16224:2615"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..267
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71925.1"
                     /translation="DYYCAMWHSSVYGLF"
     J_segment       269..306
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           74 a           99 c           86 g           85 t
ORIGIN      
        1 acatgggagc cagactcagc tgcaccttga gcagtggcat caatgttggt agttacagca
       61 tattctggta ccagcagaag ccagggagtc ctccccgatt ccttctgtac tactactcag
      121 actcaaataa tcaccagggc tctggagtcc ccagccgctt ctctggatcc aaagatactt
      181 cagccaatgc agggctttta ctgatctctg ggctccagtc tgaagatgag gctgactatt
      241 actgtgccat gtggcacagt agtgtttatg gcttattcgg aggagggacc cggctgaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01006188             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:15787:18007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006188
VERSION     KCWK01006188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15787:18007"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..436
                     /note="immunoglobulin light chain variable region"
     V_region        90..436
     V_segment       90..401
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71926.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       402..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           90 a          163 c          110 g          113 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt tagcagtggc atcaatgttg
      181 gtagttacag catattctgg taccagcaga agccagggag tcctccccgg taccttctct
      241 actactactc agactcaagt aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcaggccttt tactgatctc tgggctccag tctgaagatg
      361 aggctgacta ttactgtgcc atatggcaca gcagcgcttc ttacttcttc ggttccggga
      421 cccggctcac cgtcctgggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01006189             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:15944:9233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006189
VERSION     KCWK01006189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15944:9233"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71927.1"
                     /translation="GYYCSSFAGTNTGLI"
     J_segment       398..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          154 c          122 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctaca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagaccc
      241 caaattcatg atttatgagg tcagtcaacg gccctcaggg gtctctgatc gtatctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccagactg aggatgaggc
      361 tggttattac tgcagctcat ttgcaggtac caacactggc ttaatcggtg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01006190             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:25142:11098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006190
VERSION     KCWK01006190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25142:11098"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..429
                     /note="immunoglobulin light chain variable region"
     V_region        81..429
     V_segment       81..389
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71928.1"
                     /translation="DYYCAIGHGSGDYIF"
     J_segment       392..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          156 c          110 g          111 t
ORIGIN      
        1 acatgggaga ggctgtgtcc accatggcct ggactcctct cctcctcctg ctcctctctc
       61 actgcacagg ttccctctcc aagcctatgc tgactcagcc ggcctccctc tcagcatctc
      121 ctggagcatc agccagtctc acatgcacct tcagcggtgg catcaatgtt gctgactacc
      181 acgtacactg gtatcagcag aagccaggga gtcccccccg gtatcttctg aggtacaaat
      241 cagactcaga taagggcctg ggctctggag tccccagccg cttctctgga tccaaagatg
      301 cttcagcgaa tacagggatt ttacacatct ctggtttcca gtctgaggat gaggctgact
      361 attactgtgc cattggccac ggcagcggtg attacatctt cgctactggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCWK01006191             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:12702:5716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006191
VERSION     KCWK01006191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12702:5716"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..396
                     /gene="IGLV6-43"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71929.1"
                     /translation="DYYCQSYDSSSVLF"
     J_segment       400..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           86 a          155 c          124 g          106 t
ORIGIN      
        1 acatgggggt gtggctcagg aagcagagcc tggagcatct ccaccatggc ctgggctcca
       61 ctcctcctca cccttctcgc tcactgcaca gggtcttggg ctgaggttgt gttcactcag
      121 ccccattctg tgtcggggtc tccggggcag acggtcacca tctcctgcac ccgcagcagt
      181 ggcagcattg acaacggctt tgtgtactgg taccagcagc ggccgggcag cgctcccacc
      241 actgtgattt acaaagataa ccaaagaccc tctggggtcc ctgatcggtt ctctggctcc
      301 atcgacagct cctccaactc tgcctccctc accatctctg gactgaaatc tgaggacgag
      361 gctgactatt actgtcagtc ttatgacagc agcagtgtat tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01006192             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:4676:8809
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006192
VERSION     KCWK01006192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4676:8809"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71930.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>483
                     /gene="IGLC"
BASE COUNT           89 a          163 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atttactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctgta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgcg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacag tagtactaat gtgttattcg
      421 gaggagggac ccgtgtgacc gtcctaggtc agcccaaggc ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCWK01006193             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2111:11258:4429
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006193
VERSION     KCWK01006193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11258:4429"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71931.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           96 a          156 c          124 g          108 t
ORIGIN      
        1 acatggggag cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcgtcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aagagtgtca ccatctcctg
      181 ttctggaagc agctccaaca tcggaagtaa taatgtgtcc tggtaccagc acctcccagg
      241 aacagctccc aaactcctca tctattataa tgatcaacga ggctcaggtg tctctgaccg
      301 attctctggc tccaagtctg gcacgtcagc ctccctggcc atcagtgggc tccagaccga
      361 ggatgaggct gattattact gcgcagcgtg ggatgatagg ctgagcagtt acatcttcgc
      421 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01006194             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:16743:20833
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006194
VERSION     KCWK01006194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16743:20833"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..398
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71932.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       403..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           96 a          153 c          111 g          115 t
ORIGIN      
        1 acatggggca gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctcgca gcctgtgctg actcagccaa cctccctctc
      121 agcatctcct ggagcatcag ccagactcac ctgcaccttg agcagtggct tcagtgttgg
      181 tacttacagg atattctggt accagcagaa gccagggagt cctccccggt atcttcttaa
      241 ctaccacaca gactcagata aacaccagga ctctggagtc cccagccgct tctttggatc
      301 caaagatgct ccggccaatg cagggatttt actcatctct gggctccagt ctgaggatga
      361 ggctgactat tactgtatga tttggcacaa caatgcttat gtcttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006195             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:25820:11168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006195
VERSION     KCWK01006195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25820:11168"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71933.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006196             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:20915:18727
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006196
VERSION     KCWK01006196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20915:18727"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..386
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71934.1"
                     /translation="DYYCAAWDDSLRSYIF"
     J_segment       390..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          152 c          118 g          102 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta ataatgtgtc ctggtaccag cacctcccag gaacagctcc caaactcctc
      241 atctactata atgatcaacg aggctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcgt gggatgatag cctgaggagt tacatcttcg ctgctgggac ccgggtcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01006197             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:19256:12440
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006197
VERSION     KCWK01006197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19256:12440"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71935.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          161 c          115 g          107 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcaactcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catccactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 gtaacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcaacgaac acaggcattt tacacatctc tgggctccag tctgaggatg
      361 aggctgacta tttctgtgcc attgggcaca gcagcggtcc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01006198             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:24256:6881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006198
VERSION     KCWK01006198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:24256:6881"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71936.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          161 c          121 g          113 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg aacagtgacc
      181 tcagtgttgg tagtaaaaac atttactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gttcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006199             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:3776:10359
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006199
VERSION     KCWK01006199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:3776:10359"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..398
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71937.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       399..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           93 a          158 c          113 g          109 t
ORIGIN      
        1 acatgggggc aggaaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gccagactca gctgcacctt gagcagtggc aatgttggta
      181 gttacagcat attctggtac cagcagaagc cagggagtcc tccccggtac cttctttact
      241 actactcaga ctcaagtaac caccaggact ctggagtccc cagccgcttc tctggatcga
      301 aagatgtttc agccaatgca gggcttttac tgatctctgg gctccagtct gaagatgagg
      361 ctgactatta ctgtgccaca tggcacagca gcgcttctta catcttcggg ggggggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01006200             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:13478:16596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006200
VERSION     KCWK01006200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13478:16596"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..450
                     /note="immunoglobulin light chain variable region"
     V_region        117..450
     V_segment       117..413
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71938.1"
                     /translation="DYYCQSYDSSLSARVF"
     J_segment       415..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           87 a          163 c          130 g          108 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gctcggggag cagctccaac atcggggcgg gttattttct ccactggtac cagcagcttc
      241 caggaacggc ccccaaactc ctcatctatg aaaataataa gcgaccctca ggggtttctg
      301 atcgattctc tggctccaag tctggtacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagcctgagt gctcgggtat
      421 tcggcggagg gacccggcta accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCWK01006201             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:22531:9415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006201
VERSION     KCWK01006201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22531:9415"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..427
                     /note="immunoglobulin light chain variable region"
     V_region        82..427
     V_segment       82..388
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71939.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       390..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          153 c          121 g          105 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctct
       61 cactgcacag gttccctctc ccagcctgtg ctgactcagc caccctccct gtctgcatcc
      121 ccgggagcat cggccagact cccctgcacc ctgagcagtg acctcagtgt tggtagtaaa
      181 aacatgtact ggtaccagca gaagccaggg agcgctccca ggttattcct gtactactac
      241 tccgactcag acaaccagct gggacctggg gtccccaatc gagtctctgg ctccaaggag
      301 acctcaagta acacagcgtt tttgctcatc tctgggctcc agcctgagga cgaggccgat
      361 tatttctgcc aggtgtttga cagtagtgtt gtgttcttcg gaggagggac ccgactgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006202             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:18144:11684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006202
VERSION     KCWK01006202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18144:11684"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71940.1"
                     /translation="DYYCHVYDGSTNVLF"
     J_segment       414..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          163 c          121 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccagggcgc gctcccaggt
      241 ttttcctcta ctacaactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt ggtcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcacg tatatgacgg tagtactaat gtattattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01006203             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:14818:16156
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006203
VERSION     KCWK01006203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14818:16156"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..378
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71941.1"
                     /translation="DYYCQVWDTSLDHGLF"
     J_segment       380..416
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           89 a          144 c          126 g           95 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacttttc tcctcctcgg
       61 cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc caccctcggt
      121 gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca ttggaagtca
      181 aagtgtgcac tggtaccagc acaagccacc gcaggcccct gttctggtca tcttttatta
      241 taccgaacgg ccctcaggaa tccctgagcg aatctctggc tccaaatcag ggaacaccgc
      301 caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg
      361 ggacacaagt cttgatcacg gcttattcgg aggagggacc cggctgaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01006204             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:25243:14194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006204
VERSION     KCWK01006204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:25243:14194"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..332
                     /note="immunoglobulin light chain variable region"
     V_region        8..332
     V_segment       8..295
                     /gene="IGLV3-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <251..>304
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71942.1"
                     /translation="DYYCAAGYGSGSSWQWVF"
     J_segment       296..332
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        333..>370
                     /gene="IGLC"
BASE COUNT           74 a          117 c          110 g           69 t
ORIGIN      
        1 acatggggac ctggctcagc caccctcagt gtcggtgtcc ccaggacaga cagccaccat
       61 cacgtgctct ggaaataact tggggagtgt atatgcttcc tggtaccatc agaagccagg
      121 ccaggcccct atactggtcg tctacaaaga taccaaccgg ccctcaggga tccctgagcg
      181 attctctggc tccaactcag gggacacggc caccctgacc atcagcaggg tcgaggctgg
      241 ggatgaggcc gactactact gtgctgcagg ctatggcagt gggagcagct ggcagtgggt
      301 gttcggcgga gggacccggc taaccgtcct aggtcagccc aaggctgccc cctcggtcac
      361 tctcttcccg
//
LOCUS       KCWK01006205             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:2885:14640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006205
VERSION     KCWK01006205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:2885:14640"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..266
                     /note="immunoglobulin light chain variable region"
     V_region        8..266
     V_segment       8..227
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <197..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71943.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       229..266
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           63 a           88 c           82 g           71 t
ORIGIN      
        1 acatggggtt ggtagtaaaa acatgtactg gtaccagcag aagccaggga gcgctcccag
       61 gttattcctg tactactact ccgactcaga caaccagctg ggacctgggg tccccaatcg
      121 agtctctggc tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctgggctcca
      181 gcctgaggac gaggccgatt atttctgcca ggtgtttgac agtagtgttg tgttcttcgg
      241 aggagggacc cgactgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      301 cccg
//
LOCUS       KCWK01006206             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:22101:13851
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006206
VERSION     KCWK01006206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22101:13851"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71944.1"
                     /translation="DYYCAVWDNSLTSPLF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          153 c          114 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg ggactcccgg gcagagtgtc accatctctt gctctggaag caactccaac
      181 attggaaata attatgtata ctggtaccag cacctcccag gaacggcccc caagctcctc
      241 atctattata gttatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgaactg aggatgaggc tgattattac
      361 tgtgcagtat gggataacag cctgaccagt ccgttgttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006207             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:10129:18781
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006207
VERSION     KCWK01006207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10129:18781"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71945.1"
                     /translation="DYYCAAWDDNLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          157 c          121 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcgtcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagcaat aatgtatcct ggtaccagca gctcccagga
      241 acagctccca aactcctctt ttattataat gatcaacgag cctcaggtgt ctctgaccga
      301 ttctcttgct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gatgataacc tgagcggcta catcttcggt
      421 gctgggacgc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCWK01006208             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:25281:18907
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006208
VERSION     KCWK01006208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:25281:18907"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71946.1"
                     /translation="DYYCQVWDISSDHHVLF"
     J_segment       391..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          137 c          142 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgtggcc tcctatgatc tgactcagcc
      121 tccctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagggaa gttgtgagct ggtaccagca gaagccaccg caggcccctg tgctggtcat
      241 gtatgctgat agcgaacggc cctcagggat ccctgagcga atctctggct cgaaatcagg
      301 gaacacggcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattagta gtgatcatca tgtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01006209             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1115:18608:11465
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006209
VERSION     KCWK01006209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:18608:11465"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71947.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       413..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          162 c          122 g          110 t
ORIGIN      
        1 acatggaggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01006210             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:14356:7055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006210
VERSION     KCWK01006210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14356:7055"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71948.1"
                     /translation="VYYCAIGHSSGLYIF"
     J_segment       399..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           87 a          157 c          119 g          111 t
ORIGIN      
        1 acatgggggg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc ctccctctca
      121 gcatctcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat caatgttgct
      181 gtctaccacg tacactggta ccagcagaag ccagggagtc ccccccggta tcttctgagg
      241 tacaaatcag actcagataa gggccagggc tctggggtcc ccagccgctt ctctggatcc
      301 agtaatgctt cagcgaacac agggatttta cgcatttctg ggctccagtc tgaggatgag
      361 gctgtctatt actgtgccat tgggcacagc agcggtcttt acatcttcgg tgctgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCWK01006211             298 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:15680:3726
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006211
VERSION     KCWK01006211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15680:3726"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..260
                     /note="immunoglobulin light chain variable region"
     V_region        8..260
     V_segment       8..224
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>232
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71949.1"
                     /translation="YYYCSSYAGSHTYIF"
     J_segment       225..260
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>298
                     /gene="IGLC"
BASE COUNT           56 a           99 c           71 g           72 t
ORIGIN      
        1 acatgggagt gacatcggtg gttataacta tgtctcctgg ttccagcagc accccggcaa
       61 agcccccaaa ctcatgattt atgatgtcac tcagcggccc tcaggggtct ctgatcgctt
      121 ctctggctcc aaatctggct acacggcctc cctgaccatc tctgggctcc aggctgcgga
      181 tgaggcttat tattactgca gctcatatgc gggcagccac acttacatct tcggtactgg
      241 gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCWK01006212             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:18144:14190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006212
VERSION     KCWK01006212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18144:14190"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71950.1"
                     /translation="DYYCQVWDSSTRYAVF"
     J_segment       395..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          146 c          136 g           93 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctt actgcacagg ctctgcgacc tcctatgagc tgactcagcc
      121 accctcattg ccagcggcct caggacagac ggccaggatc gcctgtgggg gagacagcat
      181 tggaagtgaa aatgtgttct ggtaccagca gaagccacgg caggcccctg tcctggtcat
      241 ctatggtgat acgaaacggc cctcagggat ccctgagcga ttctctggct ccatctctgg
      301 gaacaccgcc accctgacca tcaacagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta ctagatacgc ggttttcggc ggagggaccc ggctaaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006213             384 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:10982:10083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006213
VERSION     KCWK01006213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 384)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 384)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10982:10083"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    22..346
                     /note="immunoglobulin light chain variable region"
     V_region        22..346
     V_segment       22..309
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <271..>318
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71951.1"
                     /translation="DYHCQVWDLNSHHLLF"
     J_segment       311..346
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        347..>384
                     /gene="IGLC"
BASE COUNT           77 a          114 c          114 g           79 t
ORIGIN      
        1 acatgggcag gctctgcggc ctcctatgat ctgactcagc caccctcgat ttcagtgtcc
       61 ccaggacaga cggccagggt cacctgtggg ggagacaaca ttgggagtga agttgtgaac
      121 tggtaccagc agaagccacc gcaggcccct gtgttggtca tctatgctga tagcgagcgg
      181 ccctcaggga tccctgaacg attctctggc tccaaatcag ggaacacggc caccctgacc
      241 atcagcgggg tcgaggccgg ggatgaggct gactatcact gtcaggtgtg ggaccttaat
      301 agtcatcatt tgttattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct
      361 gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01006214             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:21133:6501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006214
VERSION     KCWK01006214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21133:6501"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..446
                     /note="immunoglobulin light chain variable region"
     V_region        101..446
     V_segment       101..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71952.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       409..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           86 a          163 c          123 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagcagtga
      181 cctcagtgtt ggtagtaaaa acatgtactg gtaccagcag aagccaggga gcgctcccag
      241 gttattcctg tactactact ccgactcaga caagcagctg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt atttctgcca ggtgtttgac agtagtgttg tgttcttcgg
      421 aggagggacc cgactgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCWK01006215             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:18749:11278
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006215
VERSION     KCWK01006215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18749:11278"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71953.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       396..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           94 a          150 c          116 g          109 t
ORIGIN      
        1 acatggggtg gagccaggga tcccttccaa tatcagcacc atggcctgga ctctgctcct
       61 cctccagttc ctcctcactt gctgcccagg gtccaattct caggctgtag tgactcagga
      121 gccctcaatg actgtgtccc caggagggac agtcactctc acctgtgctt ccagcactgg
      181 agcagtcacc agtggtcact ctccacactg gttccagcag aaacctggac aagcccccaa
      241 gacactgatt tataatacaa actacagaca ctcctggact cctgcccggt tctcaggctc
      301 cctccttggg ggtaaagctg ccctgacact gtcaggtgcg cagcctgagg atgaggctga
      361 gtattattgt ttactgtact atagtggtgc tcagctgtta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006216             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:21536:15691
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006216
VERSION     KCWK01006216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21536:15691"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..396
                     /gene="IGLV4-105"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71954.1"
                     /translation="EYYCQTWDIGIWVF"
     J_segment       397..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           86 a          162 c          120 g          103 t
ORIGIN      
        1 acatggggag cagagccctg aggagtctgc accatggcct ggaccccaat cctcctcctc
       61 ctcctcactc tcctccttca ctgcacaggg tctctctccc agcctgtgct gactcagtcg
      121 ccctctgcct ctgcctccct gggagcctcg gtcaagctca cctgcactct gagcagtggg
      181 cactacagct ataccatcgc atggcatcaa caatatcaag ggaaggcccc tcggttcttg
      241 atgtggctta aaagtgatgg cagccacacc aagggggacg ggatccctga tcgcttctca
      301 ggctccagct ccggggctga gcgctacctc tccatctcca acctccagtc tgaggatgag
      361 gctgagtatt actgtcagac ctgggacatt ggcatttggg tattcggcgg agggacccgg
      421 ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01006217             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1105:19623:6434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006217
VERSION     KCWK01006217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19623:6434"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..446
                     /note="immunoglobulin light chain variable region"
     V_region        98..446
     V_segment       98..409
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71955.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          162 c          120 g          113 t
ORIGIN      
        1 acatgggggc cccactgtgg ggaaagaggc tgtgtccacc atggcctgga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctccaag cctatgctga ctcagccggc
      121 ctccctctca gcatctcctg gagcatcagc cagtctcaca tgcaccttca gcggtggcat
      181 caatgttgct gtctaccacg tacactggta ccagcagaag ccagggagtc ccccccggtt
      241 tcttctgagg tacaaatcag actcagataa gggccagggc tctggagtcc ccagccgctt
      301 ctctggatcc agtaatgttt cagcgaacac agggatttta cgcatttctg ggctccagtc
      361 tgaggatgag gctgactatt actgtgccat tgggcacagc agcggtcctt acatcttcgg
      421 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCWK01006218             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:18648:18756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006218
VERSION     KCWK01006218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18648:18756"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71956.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       391..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          142 c          133 g           93 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcattg acggtgcctc agccatggcc tggacccttc
       61 tcctcctcgg cctcctcgct tactgcacag gctctgcgac ctcctatgaa ctgactcagt
      121 caccctcagt gtcagcggcc tcaggacagc cggccaggat cacctgtggg ggagacaaca
      181 ttggaattaa aactgtacac tggtaccagc agaagccacc gcagggccct gtattggtca
      241 tctttgctga tagtaagcgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcaggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg ggggacccgg ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01006219             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:22573:18017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006219
VERSION     KCWK01006219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22573:18017"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..444
                     /note="immunoglobulin light chain variable region"
     V_region        96..444
     V_segment       96..407
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71957.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          162 c          117 g          111 t
ORIGIN      
        1 acatggggcc cactgtgggg aaagaggctg tgtccaccat ggcctggact cctctcctcc
       61 tcctgctcct ctctcactgc acaggttccc tctccaagcc tatgctgact cagccggcct
      121 ccctctcagc atctcctgga gcatcagcca gtctcacatg caccttcagc ggtggcatca
      181 atgttggtgt ctaccacata cactggtacc aactgaagcc agggagtccc ccccggtatc
      241 ttctgaggta caaatcagac tcagataagg gccagggctc tggagtcccc agccgcttct
      301 ctggatccag taatgcttca gcgaacacag ggattttacg catctctggg ctccagtctg
      361 aggatgaggc tgactattac tgtgccattg gacacagcag cggtccttac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01006220             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1117:25638:13742
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006220
VERSION     KCWK01006220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:25638:13742"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71958.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       404..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          152 c          117 g          116 t
ORIGIN      
        1 acatggggac tgtagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcttc tcctggagca tcagccagac tcacctgcac cttgagcagt ggcatcagtg
      181 ttggtactta caggatattc tggtaccagc agaggccagg gagtcctccc cggtatcttc
      241 tgaaccacca cacagactca gataaacatc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttgctcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttatgtgtta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006221             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:12879:2672
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006221
VERSION     KCWK01006221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12879:2672"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71959.1"
                     /translation="DYFCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           97 a          159 c          111 g          109 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcaactcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ttgcctacca catacactgg taccagcaga agccagggag tcccccccgg tatcttctga
      241 gttacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaaaatgg ttcaacaaac acaggcattt tacacatctc tgggctccag tctgaggatg
      361 aggctgacta tttctgtgcc attggacaca gcagcggtcc ttacatcttc ggtactggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01006222             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:13516:19308
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006222
VERSION     KCWK01006222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13516:19308"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..434
                     /note="immunoglobulin light chain variable region"
     V_region        87..434
     V_segment       87..394
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71960.1"
                     /translation="DYYCAIGHSSGNYIF"
     J_segment       401..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          155 c          116 g          111 t
ORIGIN      
        1 acatgggggg aaagaggctg tgtccaccat ggcctggact cctctcctcc tcctgctcct
       61 ctctcactgc acaggttccc tctcccagcc tatgctgact cagccggcct ccttctcagc
      121 atctcctgga gcttcagcca gtctcacatg caccttcagc ggtggcatca atgttgctgg
      181 ctaccacata cactggtacc agcagaagcc agggagtcct ccccggtttc ttctgagata
      241 caagtcagac tcagataagg gccagggctc tggagtcccc agccgcttct ctggatccaa
      301 ggatgcttca gcgaacacag gaattttacg catctctggg ctccagtctg aggatgaggc
      361 tgactattac tgtgccattg ggcacagcag cggtaattat atcttcggtg ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01006223             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:23087:21695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006223
VERSION     KCWK01006223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:23087:21695"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71961.1"
                     /translation="DYYCAIWHSSASYFF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          164 c          109 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac ctttagcagt ggcatcaatg
      181 ttggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tctactacta ctcagactca agtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggcc ttttcctgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacttc ttcggtactg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01006224             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2103:21578:4781
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006224
VERSION     KCWK01006224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21578:4781"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71962.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          157 c          115 g          112 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaagctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtcttata atgctgtgtc ctggtaccaa cagcatccag gcaaagcccc
      241 ccaactcata atttttgagg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgctgctcat atgtaggcag caacacttac atcttcgata ttgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCWK01006225             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:15832:17479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006225
VERSION     KCWK01006225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15832:17479"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71963.1"
                     /translation="DYYCMIWHNNAYVLF"
     J_segment       404..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          153 c          118 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcttc tcctggagca tcagccagac tcacctgcac cttgagcagt ggcatcagtg
      181 ttggtagtta caggatattc tggtaccagc agaggccagg gagtcctccc cggtatcttc
      241 tgaaccacca cacagactca gataaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttgctcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttatgtgtta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006226             350 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:16191:10155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006226
VERSION     KCWK01006226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 350)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..350
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16191:10155"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..312
                     /note="immunoglobulin light chain variable region"
     V_region        8..312
     V_segment       8..275
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <243..>284
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71964.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       276..312
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        313..>350
                     /gene="IGLC"
BASE COUNT           76 a          104 c           93 g           77 t
ORIGIN      
        1 acatgggggg agcatcggcc agactcccct gcaccctgag cagtgacctc agtgttggta
       61 ataaaaacat gtactggtac caacagaagc cagggagcgc tcccaggtta ttcctgtact
      121 actactccga ctcagacaag cagctgggac ctggggtccc caatcgagtc tctggctcca
      181 aggagacctc aactaacaca gcgtttttgc tcatctctgg gctccagcct gaggacgagg
      241 ccgattatta ctgtcaggtg tttgacagta gtgctgtgtt attcggagga gggacccgac
      301 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCWK01006227             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2108:6243:14603
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006227
VERSION     KCWK01006227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:6243:14603"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71965.1"
                     /translation="DYYCQVWDISSEHVLF"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          141 c          135 g          100 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca gcctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcggtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaggtg cagttgtgaa ttggtaccac cagaagccac cgcaggcccc tgtactggtc
      241 atctatgctg atagcgatcg gccctcaggg atccctgagc gattctctgg cttcaaatca
      301 gaaaacacgg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacattag tagtgaacat gtattattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006228             451 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:16434:8502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006228
VERSION     KCWK01006228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 451)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16434:8502"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..413
                     /note="immunoglobulin light chain variable region"
     V_region        113..413
     V_segment       113..376
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71966.1"
                     /translation="DYYCHVYDSSANVLF"
     J_segment       377..413
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>451
                     /gene="IGLC"
BASE COUNT           84 a          146 c          114 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctcccctgc actctgagca gtgacctcag tgttggtggt aaaagcatgt actggtacca
      181 gcagaagcca gggagcgctc ccaggttatt cctgttctac tactccgact cagacaagca
      241 gttgggacct ggggtcccca atcgagtctc tggctccaag gagacctcaa gtaacacagc
      301 gtttttgctc atctctgggc tccagcctga ggacgaggcc gattattact gtcacgtata
      361 tgacagtagt gctaatgtgt tattcggagg agggacccga ctgaccgtcc taggtcagcc
      421 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01006229             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:18215:4571
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006229
VERSION     KCWK01006229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18215:4571"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71967.1"
                     /translation="DYYCAAWDDSLSGPVF"
     J_segment       217..251
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           55 a           89 c           80 g           65 t
ORIGIN      
        1 acatggggga agtaatagtg tttcctggta ccagcagctc ccagaaacgg ctcccaaact
       61 cctcatcttt tataatgatc ggcgagcctc aggtgtctct gaccgattct ctggctccaa
      121 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      181 ttactgcgca gcatgggatg atagcctgag cggtccggta ttcggcggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006230             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:19792:22201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006230
VERSION     KCWK01006230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19792:22201"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..441
                     /note="immunoglobulin light chain variable region"
     V_region        108..441
     V_segment       108..401
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71968.1"
                     /translation="DYYCSSYAGSNTHWLF"
     J_segment       411..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           88 a          160 c          122 g          109 t
ORIGIN      
        1 acatgggggg ctggggtctc aggaggcagc gctctcagga cgtctccacc atggtctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccctga
      121 ctcagcctcc ctctgtgtct gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga catcggtggt tataactatg tctcctggta ccagctacac ccaggcaaag
      241 cccccaaact catgatttat gatgtcaata agcggccctc aggggtctct gatcgcttct
      301 ctggctccaa atctgacaac acggcctccc tgaccatctc tgggctccag gctgaggatg
      361 agactgatta ttactgcagc tcatatgcag gcagcaacac tcattggctt ttcggcggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006231             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:19995:16851
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006231
VERSION     KCWK01006231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19995:16851"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..251
                     /note="immunoglobulin light chain variable region"
     V_region        14..251
     V_segment       14..205
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71969.1"
                     /translation="DYYCQSYDSLSAVLF"
     J_segment       214..251
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           56 a           87 c           78 g           68 t
ORIGIN      
        1 acatgggggg gcgggttatt atgtgcagtg gtaccagcag cttccaggaa cggcccccaa
       61 actcctcatc tatgaaaatg ataagcgacc ctcaggggtt tctgatcgat tctctggctc
      121 caagtctggt acctcagcct ccctgaccat cactggactc cagtctgagg atgaggctga
      181 ttattactgc cagtcctatg acagcctgag cgctgtgtta ttcgggggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006232             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:24794:15369
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006232
VERSION     KCWK01006232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24794:15369"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71970.1"
                     /translation="DYYCQVYDDSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          121 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg caataaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtcata cagcgttttt gctcatttct ggactccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacga tagtgctgtg ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006233             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:13219:14480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006233
VERSION     KCWK01006233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13219:14480"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..422
                     /note="immunoglobulin light chain variable region"
     V_region        105..422
     V_segment       105..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71971.1"
                     /translation="DYYCYSSDSNSKWLF"
     J_segment       394..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>464
                     /gene="IGLC"
BASE COUNT           98 a          142 c          125 g           99 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccata gcctggattc
       61 ctctcctact ccccatcctc actttctgca caggctctgc agcctcctat gagatgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaaa aaaatatgct tattggttcc cgcagaaggc aggccagccc cctatggtga
      241 tcatctatga ggacaccaaa cggccctctg ggatccctga gagattctct ggctccagct
      301 cagggacagt ggccaccttg actctcagtg gggcccaggt ggaggatgaa ggtgactact
      361 actgttactc atcagacagc aatagtaaat ggctattcga cggagggacc cggctgaccg
      421 tcgtaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01006234             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:20764:7685
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006234
VERSION     KCWK01006234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20764:7685"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..414
                     /note="immunoglobulin light chain variable region"
     V_region        101..414
     V_segment       101..372
                     /gene="IGLV5-104"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71972.1"
                     /translation="DHHCKIRHDSINGYDVF"
     J_segment       377..414
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           97 a          124 c          113 g          118 t
ORIGIN      
        1 acatggggga ctggcatgtc aactgtgccc accatggcgt ggacatcttc tctttgtgct
       61 tctcttccac tgcacagatg agccagtttt cctggaccta gggagcatca gccagcctca
      121 cctgcaccct gagtagtgac atcattgtca ctgtgaaaag tttatgttgg taccagcagg
      181 ggccagggaa tcatttccgg tatctcctaa cctactactc agactcagtt aactaccagg
      241 gctatggggt ccccggccgc ttctctggat ccaaagatgt ctcaagttac tcagggattc
      301 tgcgcatctc tgggctgcag cctgaggacg aggctgatca tcattgtaag ataaggcatg
      361 acagcattaa tggttatgat gtgttcggaa gtggcaccaa gttgaccatc ctcggtcagc
      421 ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCWK01006235             455 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:21768:9466
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006235
VERSION     KCWK01006235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 455)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21768:9466"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..417
                     /note="immunoglobulin light chain variable region"
     V_region        93..417
     V_segment       93..368
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <342..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71973.1"
                     /translation="DYSCQVWDSETDHYIF"
     J_segment       380..417
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>455
                     /gene="IGLC"
BASE COUNT           89 a          145 c          129 g           92 t
ORIGIN      
        1 acatgggggg aggcagcatt gacggtgcct cagccatggc ctggaccctt ctcctcctcg
       61 gcctcctcgc tcactgcaca ggctctgcga cctcctttga gctgactcag ccaccctcgg
      121 tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac attggaatta
      181 aatttgtcca ctggtaccag cagaagccag cgcaggcccc tgtgaaggtc atctatgctg
      241 atgacaaacg gccctcaggg atccctgaga gattctctgg ctccaattca gggaacaccg
      301 ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattcc tgtcaggtgt
      361 gggacagtga gactgatcat tacatcttcg gtgctgggac ccggctcacc gtcctaggtc
      421 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCWK01006236             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:18489:15689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006236
VERSION     KCWK01006236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18489:15689"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71974.1"
                     /translation="DYYCQVWDTSIDHGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           94 a          146 c          128 g           96 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatggcc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggc ctcctatgat ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtgag ggagacaaca
      181 ttggaagtca aagtgtgcac tggtaccagc acaaaccacc gcaggcccct atactggtca
      241 tcttttatta taccgaacgg ccctcaggaa tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacacaagt attgatcacg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01006237             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:25823:10008
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006237
VERSION     KCWK01006237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:25823:10008"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71975.1"
                     /translation="DYYCHSYDSSLSGVLF"
     J_segment       414..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          154 c          127 g          114 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt cacgatctcc
      181 tgcagtggga gcaactccaa cattggatat tattatgtgc agtggtacca gcagcttcca
      241 ggaacggccc ccaaactcct catctatgaa aataataagc gaccctctgg ggtttctgat
      301 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccactcc tatgacagca gtttgagtgg tgtcttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01006238             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:16020:11142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006238
VERSION     KCWK01006238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:16020:11142"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..379
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71976.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       380..416
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           87 a          144 c          127 g           96 t
ORIGIN      
        1 acatggggga ggcagcattg acggtgcctc agccatggcc tggacttttc tcctcctcgg
       61 cctccttgct tactgcacag gctctgcggc ctccgatgat ctgactcagc caccctcggt
      121 gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca ttggaagtaa
      181 gagtgtgcac tggtaccagc acaagccacc gcaggcccct atcctggtca tctattatta
      241 taccgaacgg ccctcggcga tccctgagcg attctctggc tccaaatcag ggaacaccgc
      301 caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact gtcaggtgtg
      361 ggacactact attgatcatg gctttttcgg aggagggacc cggctgaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01006239             308 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:5776:18175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006239
VERSION     KCWK01006239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 308)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 308)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:5776:18175"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..270
                     /note="immunoglobulin light chain variable region"
     V_region        8..270
     V_segment       8..233
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <195..>242
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71977.1"
                     /translation="DYYCQSADRSPNHVFF"
     J_segment       234..270
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        271..>308
                     /gene="IGLC"
BASE COUNT           80 a           83 c           82 g           63 t
ORIGIN      
        1 acatgggctg ctctggagaa atactggcaa aaaaatatac tcagtggttc cagcagaagt
       61 caggccaggg ccctagactg gtgatatata aagacagtga gaggccctca gggatccctg
      121 agcgattctc tagctccagt tcagggacaa cagtcacctt gaccatcagc ggggcccaga
      181 cagaagatga ggctgactat tactgtcaat cagcagacag aagtcctaat catgtgtttt
      241 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      301 tcttcccg
//
LOCUS       KCWK01006240             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:17550:5186
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006240
VERSION     KCWK01006240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17550:5186"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71978.1"
                     /translation="DYYCQVWDNSNKYAIF"
     J_segment       399..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          146 c          137 g           95 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgc ggcctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccgggac agacggccag gatcacctgt gggggagaca
      181 agattggaag taaaagtgta cactggtacc agcagaggcc accgcaggcc cctgtactgg
      241 tcatctatgt tgatggcgac cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgcggc cggggatgag gctgactatt
      361 attgtcaggt gtgggataac agtaataaat acgcgatctt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01006241             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:12452:19270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006241
VERSION     KCWK01006241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12452:19270"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71979.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       407..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           90 a          161 c          120 g          108 t
ORIGIN      
        1 acatgggggc tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcaactgcac cttgagcagt ggcgtcaatg
      181 tgggtagtta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtactacca gtcagactca aggaagcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcagcc aatgcagggc tgttactgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccctatggc acagcagcgc ttcttgcatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCWK01006242             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:25013:13186
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006242
VERSION     KCWK01006242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:25013:13186"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71980.1"
                     /translation="DYYCSSYAGRNNFLF"
     J_segment       404..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          153 c          122 g          114 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggttcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcagtggaac
      181 cagcagtgat actgggtatt ataacgctgt gtcttggtac caacagcgtc catccaaagc
      241 ccccaaactc ataatttttg acgtcattaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccggg ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagaaataat tttttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006243             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:17051:8367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006243
VERSION     KCWK01006243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17051:8367"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71981.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       411..447
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           95 a          157 c          125 g          108 t
ORIGIN      
        1 acatgggggc gcagcttcag ctgtgggtac agaaggcagg actcaggaca atctccagca
       61 tggcctggtt ccctctcgtc ctcaccctcc tcactcactg tgcagggtcc tgggcccagt
      121 ctgtgctgac tcagcctccc tcagcgtctg aggccgccag gaagagtgtc accatctcct
      181 gttctggaag cagctccaac atcggaagta ataatgtgtc ctggtaccag cacctcccag
      241 gaacagctcc caaactcctc atctattata atgatcaacg aggctcaggt gtctctgacc
      301 gattctctgg ctccaagtct ggcacgtcag cctccctggc catcagtggg ctccagaccg
      361 aggatgaggc tgattattac tgcgcagcgt gggatgatag gctgagcagt tacatcttcg
      421 ctgctgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt
      481 tcccg
//
LOCUS       KCWK01006244             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1116:18846:4514
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006244
VERSION     KCWK01006244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18846:4514"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71982.1"
                     /translation="DYYCAAWDDRLSSYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          155 c          124 g          108 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcag ctccaacatc ggaagtaata atgtgtcctg gtaccagcac ctcccaggaa
      241 cagctcccaa actcctcatc tattataatg atcaacgagg ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcgtggg atgataggct gagcagttac atcttcgctg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCWK01006245             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:14649:20979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006245
VERSION     KCWK01006245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14649:20979"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71983.1"
                     /translation="DYYCFSTDTSGNRVF"
     J_segment       388..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           97 a          143 c          122 g           99 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc catcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagaagaat
      181 tgccaaaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtccagatca
      241 tctatgagga cagtaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcactgggg cccaggtgga ggatgaagct gactactact
      361 gtttctcaac agacaccagt ggtaatcggg tattcggcgg agggacccgt ctaaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01006246             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:20971:3813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006246
VERSION     KCWK01006246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20971:3813"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71984.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgt cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006247             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2102:27010:13992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006247
VERSION     KCWK01006247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:27010:13992"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..405
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71985.1"
                     /translation="DYYCALWHSSASCIF"
     J_segment       408..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           89 a          161 c          121 g          109 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcccagcctg tgctgaccca gccaacctcc
      121 ctctcagcat ctccgggagc atcagccaga ctcagctgca ccttgagcag tggcgtcaat
      181 gtgggttatt acagcatatt ctggtaccag cagaagccag ggagtcctcc ccggtacctt
      241 ctgtactacc agtcagactc aaggaagcac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc caatgcaggg ctgttactga tctctgggct ccagtctgag
      361 gatgaggctg actattactg tgccctatgg cacagcagcg cttcttgcat cttcggtggt
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01006248             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2116:10742:15261
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006248
VERSION     KCWK01006248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10742:15261"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    67..405
                     /note="immunoglobulin light chain variable region"
     V_region        67..405
     V_segment       67..366
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71986.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       368..405
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>443
                     /gene="IGLC"
BASE COUNT           82 a          144 c          117 g          100 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc
      121 cctgcaccct gagcagtgac ctcagtgttg gtagtaaaaa catgtactgg taccagcaga
      181 agccagggag cgctcccagg ttattcctgt actactactc cgactcagac aagcagctgg
      241 gacctggggt ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgtttt
      301 tgctcatctc tgggctccag cctgaggacg aggccgatta tttctgccag gtgtttgaca
      361 gtagtgttgt gttcttcgga ggagggaccc gactgaccgt cctaggtcag cccaaggctg
      421 ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006249             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:7474:12790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006249
VERSION     KCWK01006249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7474:12790"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..442
                     /note="immunoglobulin light chain variable region"
     V_region        94..442
     V_segment       94..402
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71987.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          156 c          120 g          110 t
ORIGIN      
        1 acatggggga ctgtggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tccaagccta tgctgactca gccggcctcc
      121 ctctcagcat ctcctggaac atcagccagt ctcacatgca ccttcagcgg tggcatcaat
      181 gttgttggct accacataca ctggtaccag cagaagccag ggagtcctcc ccggtatctt
      241 ctgagataca aatcggactc agataagggc cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcagc gaacgcaggg attttacgca tctctggact ccagtctgag
      361 gatgaggctg actattactg tgccattggg cacagcagcg gtgattacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCWK01006250             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1101:27276:11538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006250
VERSION     KCWK01006250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:27276:11538"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..358
                     /note="immunoglobulin light chain variable region"
     V_region        28..358
     V_segment       28..323
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <286..>330
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71988.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       324..358
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        359..>396
                     /gene="IGLC"
BASE COUNT           79 a          125 c          103 g           89 t
ORIGIN      
        1 acatgggagg gcacaggatc ctgggctcag gctgccccga ctcagactcc ctctgtggcc
       61 gggtctcctg gacagtcggt caccatctcc tgcactggaa ccagcagtga tattgggtat
      121 tatcatgctg tgtcttggta ccaacatcat ccaggcaaag cccccaaact catgatttat
      181 gaggtcaata aacggcccgc aggggtctct gatcgcttct ctggctccaa gtccggcaac
      241 acggcctccc tgaccatctc tgggctccag actgaggatg aggctgatta ttactgcagc
      301 tcatatgcag gcagcaacac tttgttcttc ggaggaggga cccggctgac cgtcctaggt
      361 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01006251             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:19649:8202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006251
VERSION     KCWK01006251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19649:8202"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71989.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          157 c          119 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca cgaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tccggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatgcagg cagcaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006252             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:19039:9702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006252
VERSION     KCWK01006252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19039:9702"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71990.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       402..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           91 a          158 c          112 g          113 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcccag cctgtgctga cccagccaac ctccctctca
      121 gcatctccgg gagcatcagt cagactcagc tgcaccttga gcagtggcat caatgttggt
      181 tcttacacca tattctggta ccagcagaag ccagggagtc ctccccggtt ccttctgtac
      241 tactactcag actcaaataa tcaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cagccaatgc agggctttta ctgatctctg ggctccagtc tgaagatgag
      361 gctgactatt actgtgccat gtggcacagc agcgcttatg ccttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01006253             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1107:25766:5999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006253
VERSION     KCWK01006253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:25766:5999"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71991.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          161 c          123 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg tcagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006254             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2114:10385:8303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006254
VERSION     KCWK01006254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10385:8303"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71992.1"
                     /translation="DYYCQVYDSSANVVF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          161 c          126 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaag atgtactggt accagcagaa ggcagggagc gctcccaggt
      241 tatacctcta ctacgactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagccttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat gtggtattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01006255             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2105:5171:20592
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006255
VERSION     KCWK01006255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5171:20592"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71993.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       395..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          150 c          137 g           94 t
ORIGIN      
        1 acatgggggt ctgggtctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc gacctcctat gagctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcccctgt gggggagaca
      181 acattggaac taaatatgtg cactggtacc agcagaagcc agcgcaggcc cctgtgttgg
      241 tcatctatgc tgataccaga cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cgggtatgag gctgactatt
      361 tctgtcaggt gtgggacgat agtagtgatc atccggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCWK01006256             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:11389:2887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006256
VERSION     KCWK01006256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11389:2887"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    62..386
                     /note="immunoglobulin light chain variable region"
     V_region        62..386
     V_segment       62..349
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <311..>358
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71994.1"
                     /translation="DYYCQVWDNIYKYAVF"
     J_segment       352..386
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        387..>424
                     /gene="IGLC"
BASE COUNT           80 a          129 c          122 g           93 t
ORIGIN      
        1 acatggggcc gggacccttc tcctcctcgg cctccttgct cactttacag gctctgtggc
       61 ctcctatgag ttgcctcagc cacgctcagt gtccgtgtcc ccaggacaga cggccaggat
      121 cacctgtggg ggagacaaca ttggaagtaa tagtgtgcat tggtaccagc agaagccacc
      181 gcgggcccct gtattggtca tctctgttga tagcgaacgg ccctcaggga tccctgagcg
      241 attctctggt tccagatcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      301 ggatgaggct gactattact gtcaggtgtg ggataatatt tataaatacg cggtattcgg
      361 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      421 cccg
//
LOCUS       KCWK01006257             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1104:19853:4676
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006257
VERSION     KCWK01006257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19853:4676"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71995.1"
                     /translation="DYYCQVFDSSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg taataaaaac atgtactggt accaacagaa gccagggagc gctctcaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtttgacag tagtgctgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006258             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:16730:9906
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006258
VERSION     KCWK01006258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16730:9906"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..391
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71996.1"
                     /translation="DYYCCSYVGSNTYIF"
     J_segment       398..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          156 c          114 g          116 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaagct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac catctcctgc actggatcca
      181 tcagtgatat tgggtcttat aatgctgtgt cttggtacca acagcatcca ggcaaagccc
      241 cccaactcat aatttttgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tgacaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgctgctca tatgtaggca gcaacactta catcttcgat gttgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCWK01006259             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:10852:16032
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006259
VERSION     KCWK01006259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10852:16032"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71997.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       391..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          150 c          136 g           91 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctatgagc tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaactaag tatgtgcact ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat accagacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg tatgaggctg actatttctg
      361 tcaggtgtgg gacgatagca gtgatcatcc ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006260             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2118:13693:10924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006260
VERSION     KCWK01006260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13693:10924"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71998.1"
                     /translation="DYYCSSYGGRNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          153 c          122 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac cagcatcatc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 ggctgattat tactgcagct catatggagg cagaaacact ttattcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006261             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:6043:10785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006261
VERSION     KCWK01006261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6043:10785"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..418
                     /note="immunoglobulin light chain variable region"
     V_region        100..418
     V_segment       100..386
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>390
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV71999.1"
                     /translation="DYYCDSWDSRGTQF"
     J_segment       387..418
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>456
                     /gene="IGLC"
BASE COUNT           94 a          138 c          125 g           99 t
ORIGIN      
        1 acatgggggg gctcagaagc agagctctgg ggtgtctcca ccatggcctg gactcctctc
       61 tggctcaccc tcctcagtct ttgcacaggt tctgtggttt cttctgagct gactcaggac
      121 cctgcagtgt ctgtggcctt gggacagaca gtcaggatca cctgccaagg agacagcctc
      181 agaagttatt atgcaagttg gtaccagcag aagccaggcc aggcccctat actgatcgtc
      241 tatggtaaca attaccggcc ctcagggatc ccagagcgat tctctggctc cagtacacga
      301 aacacagctt ccttgaccat cactggggct caggtggaag atgaggctga ctattactgt
      361 gactcctggg acagccgcgg aacccaattc ggaggaggga cccggctgac cgtcctaggt
      421 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01006262             329 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2119:15953:9780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006262
VERSION     KCWK01006262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 329)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15953:9780"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..291
                     /note="immunoglobulin light chain variable region"
     V_region        8..291
     V_segment       8..254
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72000.1"
                     /translation="DYYCQVWDTTIDHGFF"
     J_segment       255..291
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>329
                     /gene="IGLC"
BASE COUNT           71 a           98 c           95 g           65 t
ORIGIN      
        1 acatgggagg acagacggcc aggatcacct gtgggggaga caacattgga agtaagagtg
       61 tgcactggta ccagcacaag ccaccgcagg cccctatcct ggtcatctat tattataccg
      121 aacggccctc ggcgatccct gagcgattct ctggctccaa atcagggaac accgccaccc
      181 tgaccatcag cggggtcgag gccggggatg aggctgacta ttactgtcag gtgtgggaca
      241 ctactattga tcatggcttt ttcggaggag ggacccggct gaccgtccta ggtcagccca
      301 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006263             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:10239:6827
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006263
VERSION     KCWK01006263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10239:6827"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72001.1"
                     /translation="DYYCQVWDTSFDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          147 c          126 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgagg gcgacaacat
      181 tggaagtcaa agtgtgcact ggtaccaaca caaaccaccg caggccccta tactggtcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaagtt ttgatcacgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006264             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1112:11027:14592
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006264
VERSION     KCWK01006264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:11027:14592"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..411
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72002.1"
                     /translation="DYYCHVYDSSTNVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          163 c          121 g          112 t
ORIGIN      
        1 acatggggtg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtggtaaaaa catgtactgg taccagcaga agccagggcg cgctcccagg
      241 tttttcctgt actacaactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcac gtatatgaca gtagtactaa tgtgttattc
      421 ggaggaggga cccgtctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01006265             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:11910:17422
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006265
VERSION     KCWK01006265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11910:17422"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..436
                     /note="immunoglobulin light chain variable region"
     V_region        88..436
     V_segment       88..397
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72003.1"
                     /translation="DYYCMIWHNNAYWVF"
     J_segment       399..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           95 a          153 c          110 g          116 t
ORIGIN      
        1 acatggggag ggaaagaggc tgtgtccacc atggcctgga ctcctctcct cctcctgctc
       61 ctctctcact gcacaggttc cctctcgcag cctgtgctga ctcagccaac ctccctctca
      121 gcttctcctg gagcatcagc cagactcacc tgcaccttga acagtggcat cagtgttgct
      181 aattacagga tattctggta ccaccagaag ccagggagtc ctccccggta tcttctgaac
      241 taccacacag actcagatat tcaccagggc tctggagtcc ccagccgctt ctctggatcc
      301 aaagatgctt cggccaatgc agggatttta ctcatctctg gactccagtc tgaggatgag
      361 gctgactatt actgtatgat ttggcacaac aatgcttatt gggttttcgg cggagggacc
      421 cggctaaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCWK01006266             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2117:19916:18633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006266
VERSION     KCWK01006266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19916:18633"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..456
                     /note="immunoglobulin light chain variable region"
     V_region        111..456
     V_segment       111..419
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <384..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72004.1"
                     /translation="DYYCATWHSSASYIF"
     J_segment       420..456
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT          100 a          166 c          115 g          113 t
ORIGIN      
        1 acatgggcaa cgcagagtac atggggactg cagggaaaga ggctgtgtcc accatggcct
       61 ggactcctct cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc
      121 tgacccagcc aacctccctc tcagcatctc cgggaacatc agccagactc agctgcacct
      181 tgagcagtgg caatgttggt agttacagca tattctggta ccagcagaag ccagggagtc
      241 ctccccggta ccttctttac tactactcag actcaagtaa ccaccaggac tctggagtcc
      301 ccagccgctt ctctggatcg aaagatgctt cagccaatgc agggctttta ctgatctctg
      361 ggctccagtc tgaagatgag gctgactatt actgtgccac atggcacagc agcgcttctt
      421 acatcttcgg tcctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg
      481 tcactctgtt cccg
//
LOCUS       KCWK01006267             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1106:5086:17523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006267
VERSION     KCWK01006267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:5086:17523"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72005.1"
                     /translation="DYYCAAWDDSLRSPLF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          153 c          121 g          102 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgagctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctcct gctctggaag cagctccaat
      181 attggaagta attctgtata ctggtaccag cagttcccag gaacggcccc caaactcctc
      241 atctattata gtaatcagcg accctcaggg gtccctgacc gggtctctgg ctctaagtcg
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgacag cctgagaagt ccgctattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006268             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2112:4996:19277
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006268
VERSION     KCWK01006268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:4996:19277"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..448
                     /note="immunoglobulin light chain variable region"
     V_region        100..448
     V_segment       100..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72006.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       414..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          164 c          123 g          108 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcct
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcactgac
      181 ctcagtgttg gtggtaaaaa catgtactgg taccagcaga agccaggaag cgctcccagg
      241 ttattgctgt attaccactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg agaccgatta ttactgtcag gtgtatgaca gtagtgccaa cacgttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCWK01006269             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:22639:15284
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006269
VERSION     KCWK01006269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22639:15284"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..430
                     /note="immunoglobulin light chain variable region"
     V_region        101..430
     V_segment       101..394
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72007.1"
                     /translation="DYYCAAWDNSLTSPVF"
     J_segment       399..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>469
                     /gene="IGLC"
BASE COUNT           94 a          156 c          114 g          105 t
ORIGIN      
        1 acatggggag aaggcaggac tcaggataat ctccagcatg gcctggttcc ctctcgtcct
       61 caccctcctc actcactgtg cagttccagg gtcctgggcc cagtctgtgc tgactcagcc
      121 accctcagcg tctgggactc ccgggcagag tgtcaccatc tcgtgctctg gaagcagctc
      181 caacattgga actaattatg tatactggta ccaacacctc ccaggaacgg cccccaaact
      241 cctcatctat tatagtaatc agcgaccctc aggggtccct gaccgattct ctggctctaa
      301 gtctggcacc tcagcctccc tggccatcac tggtctccga tctgaggatg aggctgatta
      361 ttactgtgca gcatgggata acagcctgac cagtccggta ttcggaggag ggacccggct
      421 gaccgtccta agtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCWK01006270             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:12934:9048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006270
VERSION     KCWK01006270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12934:9048"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..387
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72008.1"
                     /translation="DYFCQVWDDSSDHPVF"
     J_segment       396..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           87 a          149 c          136 g           96 t
ORIGIN      
        1 acatggggtg tctgggtctc aggaggcagc attgacggtg cctcagccat ggcctggacc
       61 cttctcctcc tcggcctcct cgctcactgc acaggctctg cgacctccta tgagctgact
      121 cagccaccct cggtgtcagc ggcctcagga cagacggcca ggatcacctg tgggggagac
      181 aacattggaa ctaaatatgt gcactggtac cagcagaagc cagcgcaggc ccctgtgttg
      241 gtcatctatg ctgataccag acggccctca gggatccctg agcgattctc tggctccaac
      301 tcagggaaca ccgccaccct gaccatcagc ggtgtcgagg ccgggtatga ggctgactat
      361 ttctgtcagg tgtgggacga tagtagtgat catccggtat tcggcggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01006271             453 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1109:11971:14373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006271
VERSION     KCWK01006271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 453)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:11971:14373"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..415
                     /note="immunoglobulin light chain variable region"
     V_region        85..415
     V_segment       85..380
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <343..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72009.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       381..415
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>453
                     /gene="IGLC"
BASE COUNT           85 a          151 c          112 g          105 t
ORIGIN      
        1 acatggggct ctcaggactt ctccaccatg gtctgggctc tgctcctcct caccctcctc
       61 actcagggca caggatcctg ggctcaggct gccccgactc agactccctc tgtggccggg
      121 tctcctggac agtcggtcac catctcctgc actggaacca gcagtgatat tgggtattat
      181 catgctgtgt cttggtacca acatcatcca ggcaaagccc ccaaactcat gatttatgag
      241 gtcaataaac ggcccgcagg ggtctctgat cgcttctctg gctccaagtc cggcaacacg
      301 gcctccctga ccatctctgg gctccagact gaggatgagg ctgattatta ctgcagctca
      361 tatgcaggca gcaacacttt gttcttcgga ggagggaccc ggctgaccgt cctaggtcag
      421 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006272             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1119:14583:20270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006272
VERSION     KCWK01006272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14583:20270"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..392
                     /gene="IGLV7-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72010.1"
                     /translation="EYYCWLYSSDGHGLF"
     J_segment       400..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          155 c          121 g          103 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat accagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcactga ctgtgtcccc aggagggaca gtcactctca cctgtggttc cagtactgga
      181 gcggtcacca gtggtcacta tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt atgatacaac caacaaactc tcctggaccc ctgcccggtt ctcaggctcc
      301 cttgctgggg gtaaagctgc cctgacactt tcgggtgcgc agcccgagga cgaggctgaa
      361 tattactgct ggctgtattc cagtgatggt catggcttgt tcggcggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01006273             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:16941:16671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006273
VERSION     KCWK01006273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:16941:16671"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72011.1"
                     /translation="DYYCSSYAGSNTLFF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          155 c          120 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagactccc tctgtgtccg ggtctcctgg acagtcggtc accatctcct gcagtggaac
      181 cagcagtgat attgggtatt atcatgctgt gtcttggtac caacatcgtc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa acggcccgca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccaga ctgaggatga
      361 agctgattat tactgcagct catatgcagg cagcaacact ttattcttcg gacgagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCWK01006274             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1111:13874:7018
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006274
VERSION     KCWK01006274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13874:7018"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72012.1"
                     /translation="EYYCLLYYSGAQLLF"
     J_segment       395..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          150 c          117 g          107 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat atcagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtgcttc cagcactgga
      181 gcagtcacca gtggtcactc tccacactgg ttccagcaga aacctggaca agcccccaag
      241 acactgattt ataatacaaa ctacagacac tcctggactc ctgcccggtt ctcaggctcc
      301 ctccgtgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaggctgag
      361 tattattgtt tactgtacta tagtggtgct cagctgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01006275             451 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2109:23107:13119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006275
VERSION     KCWK01006275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 451)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:23107:13119"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..413
                     /note="immunoglobulin light chain variable region"
     V_region        89..413
     V_segment       89..375
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <338..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72013.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       377..413
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>451
                     /gene="IGLC"
BASE COUNT           90 a          144 c          122 g           95 t
ORIGIN      
        1 acatgggggc agcattgacg gtgcctcagc catggcctgg acttttctcc tcctcggcct
       61 ccttgcttac tgcacaggct ctgcggcctc ctatgatctg actcagccac cctcggtgtc
      121 agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaacattg gaagtcaaag
      181 tgtgcactgg taccagcaca agccaccgca ggcccctata ctggtcatct tttattatac
      241 cgaacggccc tcaggaatcc ctgagcgatt ctctggctcc aaatcaggga acaccgccac
      301 cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc aggtgtggga
      361 cacaactatt gatcacggct tattcggagg agggacccgg ctgaccgtcc taggtcagcc
      421 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01006276             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2106:17166:8770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006276
VERSION     KCWK01006276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17166:8770"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..399
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72014.1"
                     /translation="DYYCAMWHSSAYALF"
     J_segment       404..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           91 a          160 c          113 g          112 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctccc agcctgtgct gacccagcca acctccctct
      121 cagcatctcc gggagcatca gtcagactca gctgcacctt gagcagtggc atcaatgttg
      181 gttcttacac catattctgg taccagcaga agccagggag tcctccccgg ttccttctgt
      241 actactactc agactcaaat aatcaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagccaat gcagggcttt tactgatctc tgggctccag cctgaagatg
      361 aggctgacta ttactgtgcc atgtggcaca gcagcgctta tgccttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01006277             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1113:10596:4219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006277
VERSION     KCWK01006277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:10596:4219"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..409
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72015.1"
                     /translation="DYYCQVYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          164 c          122 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcactgacc
      181 tcagtgttgg tggtaaaaac atgtactggt accagcagaa gccaggaagc gctcccaggt
      241 tattgctgta ttaccactcc gactcagaca agcatctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgccaac acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCWK01006278             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:17565:12512
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006278
VERSION     KCWK01006278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17565:12512"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72016.1"
                     /translation="DYYCQVWDLNSHHLSF"
     J_segment       394..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           85 a          144 c          137 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcgatt tcagtgtccc caggacagac ggccagggtc acctgggggg gagacaacat
      181 cggaggtgaa gttgtgaatt ggtaccagca gaagccaccg caggcccctg tgttggtcat
      241 ctatgctgat agcgagcggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 cgacgcggcc accctgacca tcagcggggt cgaggccgga gatgaggctg actattactg
      361 tcaggtgtgg gaccttaata gtcatcatct ctcattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006279             451 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1103:15568:10541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006279
VERSION     KCWK01006279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 451)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:15568:10541"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..413
                     /note="immunoglobulin light chain variable region"
     V_region        83..413
     V_segment       83..374
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72017.1"
                     /translation="DYYCSSWESSLNWVF"
     J_segment       376..413
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>451
                     /gene="IGLC"
BASE COUNT           82 a          145 c          117 g          107 t
ORIGIN      
        1 acatggggca ctcaggacag tctccagcat ggcctggtct ctccttctca ctctgctggt
       61 tcactgcaca gggtcctggg cccagtctgt gctgacgcag ccgccctcag catctggggc
      121 ccccgggcag agggtcacca tctcctgctc tgggagcagc tccaacatcg gggcgggttt
      181 ttatgtttcc tggtaccagc agttcccagg aacagccccc aaactcctca tctttgaaaa
      241 taataagcga ccctcagggg tttctgaccg attctctggc tccaagtctg gttcctcagc
      301 ctccctgacc atcactggac tccaatctga ggatgaggct gattattatt gttcatcatg
      361 ggaaagcagc ctgaattggg tattcggcgg agggacccgg ctgaccgtcc taggtcagcc
      421 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCWK01006280             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:10184:7919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006280
VERSION     KCWK01006280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10184:7919"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..227
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72018.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       231..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           68 a           84 c           90 g           59 t
ORIGIN      
        1 acatgggggg ggagacaaca ttggaattaa aactgtacac tggtaccagc agaagccacc
       61 gcagggccct gtattggtca tctttgctga tagtaagcgg cccacaggga tccctgagcg
      121 attctctggc tccaactcag ggaacaccgc caccctgacc atcagcaggg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggacagtagt agtaaatgga tattcggcgg
      241 ggggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCWK01006281             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:23352:15727
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006281
VERSION     KCWK01006281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23352:15727"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72019.1"
                     /translation="DYYCQSTDGNYNRLF"
     J_segment       400..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          156 c          127 g          101 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcgtctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttctgt tcacgcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgtaccc gcagcagagg
      181 caacattgac aatagttatg tgcagtggta ccagcagcgc ccgggcagtg ccccgaccac
      241 agtgatttac agagataacc aaagagcctc tggggtccct gatcggttct ctggctccat
      301 cgacagctcc tccaactctg cctccctcac catctctggg ctgaagtctg aggacgaggc
      361 tgactactac tgtcagtcta ctgatggcaa ctacaatcgg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01006282             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2115:11236:10270
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006282
VERSION     KCWK01006282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11236:10270"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72020.1"
                     /translation="DYYCAIGHSSGPYIF"
     J_segment       402..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          159 c          114 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatact gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctaactacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attgggcaca gcagcggtcc ttacatcttc ggtcctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCWK01006283             391 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1114:16331:19003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006283
VERSION     KCWK01006283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 391)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16331:19003"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..353
                     /note="immunoglobulin light chain variable region"
     V_region        23..353
     V_segment       23..316
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <278..>325
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72021.1"
                     /translation="DYYCAAWDNSLSSYIF"
     J_segment       317..353
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        354..>391
                     /gene="IGLC"
BASE COUNT           79 a          125 c          100 g           87 t
ORIGIN      
        1 acatggggca gggtcctggg cccagtctgt gctgactcag cctccctcag cgtctgaggc
       61 cgccaggaag agtgtcacca tctcctgttc tggaagcagc tccaacatcg gaagtaataa
      121 tgtgtcctgg taccagcacc tcccaggaac agctcccaaa ctcctcatct attataatga
      181 tcagcgagac tcaggtgtct ctgaccgatt ctctggctcc aagtctggca cgtcagcctc
      241 cctggccatc agtgggctcc agaccgagga tgaggctgat tattactgcg cagcgtggga
      301 taatagcctg agcagttaca tcttcgctgc tgggacccgg ctcaccgtcc taggtcagcc
      361 caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCWK01006284             403 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2107:14008:8420
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006284
VERSION     KCWK01006284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 403)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14008:8420"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..365
                     /note="immunoglobulin light chain variable region"
     V_region        20..365
     V_segment       20..328
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <296..>337
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72022.1"
                     /translation="DYYCQVYDSSAVLF"
     J_segment       332..365
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        366..>403
                     /gene="IGLC"
BASE COUNT           81 a          129 c          104 g           89 t
ORIGIN      
        1 acatgggggt tccctctccc agcctgtgct gactcagcca ccctccctgt ctgcatcccc
       61 gggagcatcg gccagactcc cctgcaccct gagcagtgac ctcagtgttg gtagtaaaaa
      121 catgtactgg taccagcaga agccagggag cgctcccagg ttattcctgt actactactc
      181 cgactcagac aagcagctgg gacctggggt ccccaatcga gtctctggct ccaaggagac
      241 ctcaaataac acagcgtttt tgctcatctc tgggctccag cctgaggacg aggccgatta
      301 ttactgtcag gtgtatgaca gtagtgctgt attattcgga ggagggaccc ggctgaccgt
      361 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006285             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1108:14880:15347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006285
VERSION     KCWK01006285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14880:15347"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72023.1"
                     /translation="DYYCQSVDSSGNLPLF"
     J_segment       394..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          106 a          137 c          122 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatactc agtggttcca gcagcagcca ggccaggccc ctttcctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gtagacagca gtggaaatct tccgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCWK01006286             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1102:13280:11012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006286
VERSION     KCWK01006286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13280:11012"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72024.1"
                     /translation="DYFCQVFDSSVVFF"
     J_segment       407..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          122 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc actcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgccagg tgtttgacag tagtgttgtg ttcttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCWK01006287             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:6423:12789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006287
VERSION     KCWK01006287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6423:12789"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72025.1"
                     /translation="DYYCQVWDTTIDHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          147 c          128 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatggcct ggacttttct
       61 cttcctcggc ctccttgctt actgcacagg ctctgcggcc tcctatgatc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtcaa agtgtacact ggtaccagca caagccaccg caggcccctg ttctgctcat
      241 cttttattat accgaacggc cctcaggaat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacacaacta ttgatcacgg cttgttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCWK01006288             311 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2113:20880:13506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006288
VERSION     KCWK01006288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 311)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 311)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..311
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20880:13506"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..273
                     /note="immunoglobulin light chain variable region"
     V_region        7..273
     V_segment       7..237
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <201..>245
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72026.1"
                     /translation="DYYCQVWDSSSKWIF"
     J_segment       241..273
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        274..>311
                     /gene="IGLC"
BASE COUNT           69 a           88 c           92 g           62 t
ORIGIN      
        1 acatggggat cacctgtggg ggagacaaca ttggaactaa aactgtgcac tggtaccagc
       61 agaagccacc gcagggccct gtattggtca tctttgctga tagtaaacgg ccctcaggga
      121 tccctgagcg attctctggc tccaactcag ggaacaccgc caccctgacc atcagcaggg
      181 tcgaggccgg ggatgaggct gactattact gtcaggtgtg ggacagtagt agtaaatgga
      241 tattcggcgg ggggacccgg ctaaccgtcc taggtcagcc caaggctgcc ccctcggtca
      301 ctctcttccc g
//
LOCUS       KCWK01006289             342 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2110:11807:10474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006289
VERSION     KCWK01006289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 342)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11807:10474"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..304
                     /note="immunoglobulin light chain variable region"
     V_region        7..304
     V_segment       7..267
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <229..>276
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72027.1"
                     /translation="DYYCAAWDNSLTSPLL"
     J_segment       270..304
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        305..>342
                     /gene="IGLC"
BASE COUNT           70 a          109 c           85 g           78 t
ORIGIN      
        1 acatgggggg ctcccgggca gagtgtcacc atctcttgct ctggaagcag ctccaacatt
       61 ggaactaatt atgtatactg gtaccagcag ctcccaggaa cggcccccaa agtcctcatc
      121 tattatagta atcagcgacc ctcaggggtc cctgaccgat tctctgcctc taagtctggc
      181 acctcagcct ccctggccat cactggtctc cgatctgagg atgaggctga ttattactgt
      241 gcagcgtggg ataacagcct aactagtccg ttactcggag gagggacccg gctgaccgtc
      301 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCWK01006290             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:1118:19003:3853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006290
VERSION     KCWK01006290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:19003:3853"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72028.1"
                     /translation="DYYCQVWDIYTDHPVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          143 c          136 g          101 t
ORIGIN      
        1 acatgggggg gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtg aagttgtcaa ctggtaccaa cagaagccac cgcaggcccc tgtggtggtc
      241 atctatgctg attatgaacg gccctcaggg atccctgacc gattctctgg ctccaaatca
      301 gggaacacgg ccaccctgac catcagcgga gtcgcggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacattta tactgatcat ccggtgttgt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCWK01006291             496 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RTh16 RLN 28:1:2104:9811:18595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCWK01006291
VERSION     KCWK01006291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872182
            Sequence Read Archive: SRR8582682, SRR8582727
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 496)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9811:18595"
                     /isolate="RTh16 RLN"
                     /db_xref="taxon:9544"
                     /sex="male"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..458
                     /note="immunoglobulin light chain variable region"
     V_region        110..458
     V_segment       110..421
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>430
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72029.1"
                     /translation="DYYCQVYDSSANVLF"
     J_segment       422..458
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        459..>496
                     /gene="IGLC"
BASE COUNT           94 a          169 c          123 g          110 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      181 gagcagtgac ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag
      241 cgctcccagg tcattcctgt actactactc cgactcagac aagcagctgg gacctggggt
      301 ccccaatcga gtctctggct ccaaggagac ctcaactaac acagcgtttt tgctcatctc
      361 tggactccag cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtagtgctaa
      421 tgtgttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      481 ggtcactctc ttcccg
//
